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https://www.readbyqxmd.com/read/29774894/value-of-diffusion-weighted-imaging-for-monitoring-tissue-change-during-magnetic-resonance-guided-high-intensity-focused-ultrasound-therapy-in-bone-applications-an-ex-vivo-study
#1
Sharon L Giles, Jessica M Winfield, David J Collins, Ian Rivens, John Civale, Gail R Ter Haar, Nandita M deSouza
Background: Magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU) can palliate metastatic bone pain by periosteal neurolysis. We investigated the value of diffusion-weighted imaging (DWI) for monitoring soft tissue changes adjacent to bone during MR-guided HIFU. We evaluated the repeatability of the apparent diffusion coefficient (ADC) measurement, the temporal evolution of ADC change after sonication, and its relationship with thermal parameters. Methods: Ex-vivo experiments in lamb legs ( n = 8) were performed on a Sonalleve MR-guided HIFU system...
2018: European radiology experimental
https://www.readbyqxmd.com/read/29773338/taking-stock-a-systematic-review-of-archaeological-evidence-of-cancers-in-human-and-early-hominin-remains
#2
Kathryn J Hunt, Charlotte Roberts, Casey Kirkpatrick
This study summarizes data from 154 paleopathological studies documenting 272 archaeologically recovered individuals exhibiting skeletal or soft tissue evidence of cancer (malignant neoplastic disease) between 1.8 million years ago and 1900 CE. The paper reviews and summarizes the temporal, spatial and demographic distribution of the evidence and the methods used to provide the cancer diagnoses. Metastasis to bone is the most widely reported evidence (n = 161), followed by multiple myeloma (n = 55)...
May 14, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29771884/-exophthalmometry-with-computed-tomography
#3
M B Gushchina, D S Afanasyeva, S A Borzenok
Bone abnormalities of orbit seen in patients with trauma or radiolesion are accompanied by enophthalmos or exophthalmos. Conventional measurements of eyeball protrusion with Hertel's exophthalmometer or with computed tomography do not provide accurate and reliable data, especially in patients with asymmetry of lateral orbital rims. PURPOSE: To develop a method of computed exophthalmometry that provides accurate and reliable measurements in patients with various orbital conditions. MATERIAL AND METHODS: Medical records and computerized axial tomography scans of 25 patients' orbits without false enophthalmos or exophthalmos were analyzed posthoc...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29771830/the-effect-of-transtemperal-approach-and-placement-of-intracranial-pressure-sensor-into-temporal-horn-of-lateral-ventricle-in-management-of-spontaneous-supratentorial-intracerebral-hemorrhage-broken-into-ventricles
#4
Fei Wang, Tao Yang, Chaoshi Niu
To investigate the effect of transtemperal approach and placement of intracranial pressure sensor into temporal horn of lateral ventricle in management of spontaneous supratentorial intracerebral hemorrhage broken into ventricles, a total of 37 patients with spontaneous supratentorial intracerebral hemorrhage broken into ventricles treated by operation from January 2016 to December 20l6 were analyzed retrospectively, of which 25 patients in simple transtemporal approach group and 12 patients in transtemperal approach and placement of intracranial pressure sensor into temporal horn of lateral ventricle group...
May 15, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29770252/utility-of-magnetic-resonance-cisternography-with-intrathecal-gadolinium-in-detection-of-cerebrospinal-fluid-fistula-associated-with-mondini-dysplasia-in-a-patient-with-recurrent-meningitis-case-report-and-literature-review
#5
Enrique Caro-Osorio, Alba Espino-Ojeda, Lino Guevara-Maldonado, José C Herrea-Castro
Background: The intrathecal contrast-enhanced magnetic resonance cisternography (MRC) is a diagnostic method that has been proven effective in selected patients with various disorders of the cerebrospinal system, including the detection of cerebrospinal fluid (CSF) leaks. The Mondini dysplasia is a malformation of the inner ear characterized by an incomplete cochlear development. The cerebrospinal fistula associated with Mondini dysplasia usually occurs in the first 5-10 years. Case Description: The case of a 34-year-old woman with CSF rhinorrhea and recurrent meningitis associated with CSF fistula into the right inner ear, which was detected by MRC with intrathecal gadolinium, is presented...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29764792/otitis-media-with-effusion-revealing-underlying-meningioma
#6
Diane Evrard, Mary Daval, Denis Ayache
Otitis media with effusion (OME) is a very common condition in the current clinical practice. Usually idiopathic, it may sometimes be the consequence of primary diseases. Extracranial meningioma is rare, and even more when involving the ear and temporal bone. We report a case of temporal meningioma spreading to the middle ear and mastoid presenting as an OME. The diagnosis relies on a thorough imaging evaluation with computed tomography and magnetic resonance imaging. This short report aims to warn the otolaryngologist of this rare situation to prevent any delay in diagnosing and managing such a condition...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29764791/giant-cell-tumor-of-the-temporal-bone-and-skull-base-a-case-report
#7
İsa Kaya, Murat Benzer, Göksel Turhal, Gode Sercan, Cem Bilgen, Tayfun Kirazlı
Giant cell tumor (GCT) is a benign tumor that originates from undifferentiated mesenchymal cells of the bone marrow. The cranium as well as temporal bone is a rare location for GCTs. Despite its benign nature, GCT may be locally aggressive and has the potential to recur locally. Furthermore, GCT may give rise to pulmonary metastases (~1%) in addition to causing local bone destruction. Surgical excision is the treatment of choice for patients with GCT. We describe the case of a 56-year-old female who presented with headache and hearing loss with extensive GCT, which originated in the squamous part of the temporal bone and extended into the left mandibular fossa and middle ear...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29764198/temporal-bone-contrast-enhanced-high-resolution-ct-evaluation-of-pulsatile-tinnitus-after-sigmoid-sinus-wall-reconstruction
#8
Heyu Ding, Pengfei Zhao, Han Lv, Xuehuan Liu, Rong Zeng, Guopeng Wang, Shusheng Gong, Zhenchang Wang
Background Sigmoid sinus wall reconstruction (SSWR) is a proven effective treatment for pulsatile tinnitus (PT) caused by sigmoid sinus wall dehiscence (SSWD) with or without sigmoid sinus diverticulum (SSD); however, comprehensive analysis of the postoperative imaging manifestations has not yet been reported. Purpose To analyze temporal bone computed tomography (CT) imaging features following SSWR in patients with PT. Material and Methods Following SSWR, temporal bone contrast-enhanced high-resolution CT (HRCT) images from 33 PT cases were retrospectively analyzed...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29759935/applied-anatomy-of-round-window-and-adjacent-structures-of-tympanum-related-to-cochlear-implantation
#9
Shraddha Jain, Sagar Gaurkar, Prasad T Deshmukh, Mohnish Khatri, Sanika Kalambe, Pooja Lakhotia, Deepshikha Chandravanshi, Ashish Disawal
INTRODUCTION: Various aspects of the round window anatomy and anatomy of posterior tympanum have relevant implications for designing cochlear implant electrodes and visualizing the round window through facial recess. Preoperative information about possible anatomical variations of the round window and its relationships to the adjacent neurovascular structures can help reduce complications in cochlear implant surgery. OBJECTIVE: The present study was undertaken to assess the common variations in round window anatomy and the relationships to structures of the tympanum that may be relevant for cochlear implant surgery...
April 19, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29756238/otopathologic-evaluation-of-temporalis-fascia-grafts-following-successful-tympanoplasty-in-humans
#10
Danielle R Trakimas, Reuven Ishai, Iman Ghanad, Nicole L Black, Elliott D Kozin, Jeffrey Tao Cheng, Aaron K Remenschneider
OBJECTIVE: Temporalis fascia is a commonly used graft material in tympanoplasty; however, little is known about how the histological structure of fascia remodels postimplantation. Herein, we aim to quantify the pre- and postoperative microstructure of temporalis fascia and compare histological findings to the native tympanic membrane (TM). METHODS: Temporal bone specimens having undergone successful subtotal or total drum replacement using temporalis fascia were identified (n = 3)...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29754138/lateral-semicircular-canal-osteoma-presenting-as-chronic-postaural-fistula
#11
Charn Gill, Jameel Muzaffar, Raghu Sampath Kumar, Richard Irving
Temporal bone osteoma is an unusual pathology which can occur by birth or can be acquired and mostly involves the tympanomastoid segment of the temporal bone. Osteomas arising from the otic capsule are extremely rare, and there has been only one other report of a lateral semicircular canal osteoma in the literature. We report a similar case of an acquired lateral canal osteoma which presented as a chronic postaural fistula in an ear previously operated for paediatric cholesteatoma.
May 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29747060/acoustic-stimulation-on-the-round-window-for-active-middle-ear-implants
#12
Kiwoong Seong, Kyuyup Lee, Sunil Puria, Jin-Ho Cho
Many clinical reports have discussed the effectiveness of stimulating the ear's round window (RW) with a tool to mitigate conductive and mixed hearing loss. The RW is one of the two openings from the middle ear into the inner ear. Various methods have been proposed to construct a highly efficient, easily implanted, and reliable RW transducer. Devices, however, such as floating mass transducers, have difficulty establishing proper contact without some degree of bone incision around the RW. Additionally, vibration energy may not be fully transmitted to the cochlea, but instead will be spread through the soft tissue around the transducer...
May 2, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29745809/immunoelectron-microscopic-localization-of-collagen-type-xv-during-human-mesenchymal-stem-cells-mineralization
#13
Cristina Manferdini, Nicoletta Zini, Elena Gabusi, Francesca Paolella, Elisabetta Lambertini, Letizia Penolazzi, Roberta Piva, Gina Lisignoli
Purpose/Aim of the study. Collagen type XV (ColXV) was identified, in our previews studies, as a novel component of bone extracellular matrix. The present study aims to investigate ColXV localization during mineralization of osteodifferentiated human mesenchymal stem cells (hMSCs). MATERIAL AND METHODS: hMSCs cultured in osteogenic medium have been analyzed at day 14 and 28 for mineral matrix deposition by alizarin red S staining, ultrastructural analysis and ColXV localization by immunogold electron microscopy...
December 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29745808/the-er-ca-2-sensor-stim1-can-activate-osteoblast-and-odontoblast-differentiation-in-mineralized-tissues
#14
Yinghua Chen, Amsaveni Ramachandran, Youbin Zhang, Rahul Koshy, Anne George
Bone and dentin development requires temporal and spatial deposition of calcium phosphate mineral. A host of proteins works in concert to contribute to this tightly regulated process while malfunction in this scheme often leads to pathological defects. We have reported earlier that DMP1 stimulation of preosteoblasts leads to calcium release from internal Ca2+ stores and this store depletion is sensed by the ER Ca2+ sensor STIM1 (stromal interaction molecule 1). In this study, we first assessed the temporal and spatial localization of STIM1 protein during the development of bone and dentin by immunohistochemical methods...
December 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29738386/prevalence-of-extracochlear-electrodes-computerized-tomography-scans-cochlear-implant-maps-and-operative-reports
#15
Jourdan T Holder, David M Kessler, Jack H Noble, René H Gifford, Robert F Labadie
OBJECTIVE: To quantify and compare the number of cochlear implant (CI) electrodes found to be extracochlear on postoperative computerized tomography (CT) scans, the number of basal electrodes deactivated during standard CI mapping (without knowledge of the postoperative CT scan), and the extent of electrode insertion noted by the surgeon. STUDY DESIGN: Retrospective. SETTING: Academic Medical Center. METHODS: Two hundred sixty-two patients underwent standard cochlear implantation and postoperative temporal bone CT scanning...
June 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29733278/design-and-characterization-of-an-acoustically-and-structurally-matched-3-d-printed-model-for-transcranial-ultrasound-imaging
#16
Chen Bai, Meiling Ji, Ayache Bouakaz, Yujin Zong, Mingxi Wan
For investigating human transcranial ultrasound imaging (TUI) through the temporal bone, an intact human skull is needed. Since it is complex and expensive to obtain one, it requires that experiments are performed without excision or abrasion of the skull. Besides, to mimic blood circulation for the vessel target, cellulose tubes generally fit the vessel simulation with straight linear features. These issues, which limit experimental studies, can be overcome by designing a 3-D-printed skull model with acoustic and dimensional properties that match a real skull and a vessel model with curve and bifurcation...
May 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29730490/increased-double-limb-support-times-during-walking-in-right-limb-dominant-healthy-older-adults-with-low-bone-density
#17
Paul S Sung
BACKGROUND: Older adults with low bone mineral density (BMD) may exhibit early markers for physical frailty; however, there is a lack of understanding of the dominant limb support patterns during walking. RESEARCH QUESTION: The purpose of this study was to investigate limb support times during walking in healthy older adults with low BMD. METHODS: Seventy-seven right limb dominant older adults (48 female subjects, 29 male subjects) participated in the study...
April 25, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29728409/subchondral-drilling-for-articular-cartilage-repair-a-systematic-review-of-translational-research
#18
Liang Gao, Lars K H Goebel, Patrick Orth, Magali Cucchiarini, Henning Madry
Articular cartilage defects may initiate osteoarthritis. Subchondral drilling, a widely applied clinical technique to treat small cartilage defects, does not yield cartilage regeneration. Various translational studies aiming to improve the outcome of drilling have been performed, however, a robust systematic analysis of its translational evidence has been still lacking. Here, we performed a systematic review of the outcome of subchondral drilling for knee cartilage repair in translational animal models. A total of 12 relevant publications studying 198 animals were identified, detailed study characteristics were extracted, and methodological quality and risk of bias were analyzed...
May 3, 2018: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/29728172/hearing-loss-in-pediatric-temporal-bone-fractures-evaluating-two-radiographic-classification-systems-as-prognosticators
#19
A Bhindi, L Carpineta, B Al Qassabi, S Waissbluth, R Ywakim, J J Manoukian, L H P Nguyen
INTRODUCTION: Temporal bone fractures (TBF) are traditionally classified by their angle of fracture relative to the petrous ridge, and more recently by whether or not they violate the otic-capsule. This study compared rates of hearing loss (HL) and signs of otologic dysfunction among fracture types of both classification systems, within the pediatric population. METHODS: Pediatric patients were retrospectively characterized from a previously identified cohort of TBF patients, diagnosed from 2000 to 2014...
June 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29728168/external-auditory-canal-inferior-posterior-inferior-and-anterior-canal-wall-overhangs
#20
Kavita Dedhia, Robert F Yellon, Barton F Branstetter, Mark Best
OBJECTIVES: To characterize anatomic variants of the external ear canal (EAC), specifically canal wall overhangs. EAC overhangs are problematic since they obstruct the view of the tympanic membrane (TM) and middle ear, possibly creating diagnostic and surgical difficulties. METHODS: We reviewed pre-operative temporal bone CTs from children with cholesteatoma, and no history of EAC erosion or surgery. We measured the anterior canal wall overhang (ACOH), inferior (ICOH), and posterior-inferior (PICOH)...
June 2018: International Journal of Pediatric Otorhinolaryngology
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