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Xi Zhang, Nicole Rowan, Bethann Mangel Pflugeisen, Sanjin Alajbegovic
BACKGROUND: Antibiotics are overprescribed for abnormal urine tests including asymptomatic bacteriuria (AB), contributing to rising antimicrobial resistance rates. Pharmacists reviewed urine cultures daily from emergency department (ED) encounters to assess antibiotic appropriateness. We studied antibiotic prescribing practices and assessed compliance to national guidelines, correlations with urine analysis (UA) components, and opportunities for antimicrobial stewardship in the ED. METHODS: This quality improvement project (QIP) was a prospective cohort study at a community hospital ED, with data collected from finalized urine cultures resulting October 30, 2014 through January 5, 2015...
December 16, 2016: American Journal of Emergency Medicine
Krishnan Sriram, Suela Sulo, Gretchen VanDerBosch, Jamie Partridge, Josh Feldstein, Refaat A Hegazi, Wm Thomas Summerfelt
BACKGROUND: Although screening patients for malnutrition risk on hospital admission is standard of care, nutrition shortfalls are undertreated. Nutrition interventions can improve outcomes. We tested effects of a nutrition-focused quality improvement program (QIP) on hospital readmission and length of stay (LOS). MATERIALS AND METHODS: QIP included malnutrition risk screening at admission, prompt initiation of oral nutrition supplements (ONS) for at-risk patients, and nutrition support...
December 6, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
(no author information available yet)
This rule updates and makes revisions to the End-Stage Renal Disease (ESRD) Prospective Payment System (PPS) for calendar year 2017. It also finalizes policies for coverage and payment for renal dialysis services furnished by an ESRD facility to individuals with acute kidney injury. This rule also sets forth requirements for the ESRD Quality Incentive Program, including the inclusion of new quality measures beginning with payment year (PY) 2020 and provides updates to programmatic policies for the PY 2018 and PY 2019 ESRD QIP...
November 4, 2016: Federal Register
Dana A Telem, Saniea F Majid, Kinga Powers, Eric DeMaria, John Morton, Daniel B Jones
BACKGROUND: The American Society for Metabolic and Bariatric Surgery (ASMBS) Quality Improvement and Patient Safety (QIPS) Committee hypothesized that collecting and sharing clinical pathways could provide a valuable resource to new and existing bariatric programs. OBJECTIVE: To shed light on the variability in practice patterns across the country by analyzing pathways. SETTING: United States Centers of Excellence METHODS: From June 2014 to April 2015, clinical pathways pertaining to preoperative, intraoperative, and postoperative management of bariatric patients were solicited from the ASMBS executive council (EC), QIPS committee members, and state chapter presidents...
August 3, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Chung-Jui Yu, Michael J Graham, Joseph M Zadrozny, Jens Niklas, Matthew D Krzyaniak, Michael R Wasielewski, Oleg G Poluektov, Danna E Freedman
Quantum information processing (QIP) offers the potential to create new frontiers in fields ranging from quantum biology to cryptography. Two key figures of merit for electronic spin qubits, the smallest units of QIP, are the coherence time (T2), the lifetime of the qubit, and the spin-lattice relaxation time (T1), the thermally defined upper limit of T2. To achieve QIP, processable qubits with long coherence times are required. Recent studies on (Ph4P-d20)2[V(C8S8)3], a vanadium-based qubit, demonstrate that millisecond T2 times are achievable in transition metal complexes with nuclear spin-free environments...
November 9, 2016: Journal of the American Chemical Society
Erin L Seifert, Aniko Gál, Michelle G Acoba, Qipei Li, Lauren Anderson-Pullinger, Tunde Golenár, Cynthia Moffat, Neal Sondheimer, Steven M Claypool, György Hajnóczky
The relevance of mitochondrial phosphate carrier (PiC), encoded by SLC25A3, in bioenergetics is well accepted. However, little is known about the mechanisms mediating the cellular impairments induced by pathological SLC25A3 variants. To this end, we investigated the pathogenicity of a novel compound heterozygous mutation in SLC25A3 First, each variant was modeled in yeast, revealing that substituting GSSAS for QIP within the fifth matrix loop is incompatible with survival on non-fermentable substrate, whereas the L200W variant is functionally neutral...
December 9, 2016: Journal of Biological Chemistry
Mehdi Ammi, Christine Peyron
Despite increasing popularity, quality improvement programs (QIP) have had modest and variable impacts on enhancing the quality of physician practice. We investigate the heterogeneity of physicians' preferences as a potential explanation of these mixed results in France, where the national voluntary QIP - the CAPI - has been cancelled due to its unpopularity. We rely on a discrete choice experiment to elicit heterogeneity in physicians' preferences for the financial and non-financial components of QIP. Using mixed and latent class logit models, results show that the two models should be used in concert to shed light on different aspects of the heterogeneity in preferences...
December 2016: Health Economics Review
Darren Fernandes, Udayaraj Umasankar
Ischaemic stroke can result in approximately 2 million brain neurones being damaged for each minute that it is left untreated. Various trials and studies such as the National Institute of Neurologic Disorders (NINDS) trial, the European Cooperative Acute Stroke Study (ECASS), ECASS II, and the Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke (ATLANTIS) study have clearly demonstrated the beneficial effects of intravenous tissue plasminogen activator (tPA) for treatment of acute stroke...
2016: BMJ Quality Improvement Reports
Wen-Xue Cui, Shi Hu, Hong-Fu Wang, Ai-Dong Zhu, Shou Zhang
We propose a specific method for converting a four-photon Greenberger-Horne-Zeilinger (GHZ) state to a W state in a deterministic way by using linear optical elements, cross-Kerr nonlinearities, and homodyne measurement. We consider the effects of the quadrature homodyne measurements on the fidelity of the W state and the experimental feasibility of the proposed scheme. This might provide great prospects for converting multipartite entangled states into each other for future optical quantum information processing (QIP)...
July 11, 2016: Optics Express
C C M Marres, A W H van de Ven, P C M Verbeek, S van Dieren, W A Bemelman, C J Buskens
PURPOSE: The aim of this study was to evaluate whether implementation of a comprehensive quality improvement program was associated with improved outcomes in patients undergoing oncological colorectal surgery in a non-academic, non-referral community hospital. METHODS: The quality improvement program (QIP) was introduced in January 2011 and consisted of the following interventions: (1) avoidance of postoperative nonsteriodal anti-inflammatory drugs; (2) normovolemia was pursued pre- and postoperatively; (3) non-resectional surgery if possible, in patients over 80 with ASA 3 or 4 classification; and (4) a standardized, postoperative surveillance protocol was introduced, with CRP determination day 2 and 4, and if necessary subsequent abdominal CT with rectal contrast to reduce delay in diagnosis of complications...
September 2016: International Journal of Colorectal Disease
Daniel Cooper
It is well established that patient feedback is key to service development and improvement in the modern NHS. Certain patient groups can be particularly difficult to get feedback from, including those with dementia. The Later Life Mental Health Liaison Team at the Bristol Royal Infirmary were consistently receiving very low levels of patient feedback, such that it was insufficient to properly contribute to future service development and improvement. This QIP aimed to increase this level of feedback to a target of 15% from an existing average of 3%...
2016: BMJ Quality Improvement Reports
Joseph M Zadrozny, Jens Niklas, Oleg G Poluektov, Danna E Freedman
Quantum information processing (QIP) could revolutionize areas ranging from chemical modeling to cryptography. One key figure of merit for the smallest unit for QIP, the qubit, is the coherence time (T 2), which establishes the lifetime for the qubit. Transition metal complexes offer tremendous potential as tunable qubits, yet their development is hampered by the absence of synthetic design principles to achieve a long T 2. We harnessed molecular design to create a series of qubits, (Ph4P)2[V(C8S8)3] (1), (Ph4P)2[V(β-C3S5)3] (2), (Ph4P)2[V(α-C3S5)3] (3), and (Ph4P)2[V(C3S4O)3] (4), with T 2s of 1-4 μs at 80 K in protiated and deuterated environments...
December 23, 2015: ACS Central Science
Mei Ling Denney, Sharon Wiener-Ogilvie
There is limited evidence on the effectiveness of educational initiatives designed to support and encourage training doctors to undertake quality improvement projects (QIP) at their workplace. The purpose of this study was to examine the feasibility of the RCGP proposal to implement a QIP in the final year of training. An educational intervention was designed and delivered to a group of GP trainees six months before the end of their training. This comprised facilitated small group work, web resources and guiding paperwork to structure meetings between the trainee and trainer to monitor and support the development of the project...
March 2016: Education for Primary Care
Marianna Feretzaki, R Blake Billmyre, Shelly Applen Clancey, Xuying Wang, Joseph Heitman
RNAi is a ubiquitous pathway that serves central functions throughout eukaryotes, including maintenance of genome stability and repression of transposon expression and movement. However, a number of organisms have lost their RNAi pathways, including the model yeast Saccharomyces cerevisiae, the maize pathogen Ustilago maydis, the human pathogen Cryptococcus deuterogattii, and some human parasite pathogens, suggesting there may be adaptive benefits associated with both retention and loss of RNAi. By comparing the RNAi-deficient genome of the Pacific Northwest Outbreak C...
March 2016: PLoS Genetics
Vanessa Rameh, Antoine Kossaify
BACKGROUND: Appropriate use criteria (AUC) in echocardiography are essential tools for aligning the indications of echocardiography with the best clinical standards, improving clinical outcome, restraining abuse, and preserving health-care resources. OBJECTIVES: The aim of this study was to ascertain the AUC for transthoracic echocardiography in a university hospital and create a quality improvement project (QIP). METHODS: The assessment of 501 inpatients who received transthoracic cardiac echo was conducted according to the 2011 AUC report...
2016: Clinical Medicine Insights. Cardiology
Tong Liu, Xiao-Zhi Cao, Qi-Ping Su, Shao-Jie Xiong, Chui-Ping Yang
Cavity-based large scale quantum information processing (QIP) may involve multiple cavities and require performing various quantum logic operations on qubits distributed in different cavities. Geometric-phase-based quantum computing has drawn much attention recently, which offers advantages against inaccuracies and local fluctuations. In addition, multiqubit gates are particularly appealing and play important roles in QIP. We here present a simple and efficient scheme for realizing a multi-target-qubit unconventional geometric phase gate in a multi-cavity system...
2016: Scientific Reports
Wei Geng, Mathieu Manceau, Nancy Rahbany, Vincent Sallet, Massimo De Vittorio, Luigi Carbone, Quentin Glorieux, Alberto Bramati, Christophe Couteau
Nowadays, integrated photonics is a key technology in quantum information processing (QIP) but achieving all-optical buses for quantum networks with efficient integration of single photon emitters remains a challenge. Photonic crystals and cavities are good candidates but do not tackle how to effectively address a nanoscale emitter. Using a nanowire nanowaveguide, we realise an hybrid nanodevice which locally excites a single photon source (SPS). The nanowire acts as a passive or active sub-wavelength waveguide to excite the quantum emitter...
2016: Scientific Reports
Mailea R Miller-Pierce, Neil A Rhoads
In Maui, Hawai'i, wastewater reclamation facilities (WWRFs) dispose of partially treated effluent into injection wells connected to the nearshore environment. Hawai'i State Department of Health data from 2004-2015 were assessed for qualitative trends in nutrient, turbidity, and Chlorophyll a water quality (WQ) impairments for fourteen marine sites on Maui Island. We introduce a novel method, the Qualitative Impact Percentage (QIP), to facilitate a qualitative comparison of disparate factors contributing to WQ impairment...
February 15, 2016: Marine Pollution Bulletin
Antonio Fernandez, Jesus Ferrando-Soria, Eufemio Moreno Pineda, Floriana Tuna, Iñigo J Vitorica-Yrezabal, Christiane Knappke, Jakub Ujma, Christopher A Muryn, Grigore A Timco, Perdita E Barran, Arzhang Ardavan, Richard E P Winpenny
Quantum information processing (QIP) would require that the individual units involved--qubits--communicate to other qubits while retaining their identity. In many ways this resembles the way supramolecular chemistry brings together individual molecules into interlocked structures, where the assembly has one identity but where the individual components are still recognizable. Here a fully modular supramolecular strategy has been to link hybrid organic-inorganic [2]- and [3]-rotaxanes into still larger [4]-, [5]- and [7]-rotaxanes...
2016: Nature Communications
C J Ballance, V M Schäfer, J P Home, D J Szwer, S C Webster, D T C Allcock, N M Linke, T P Harty, D P L Aude Craik, D N Stacey, A M Steane, D M Lucas
Entanglement is one of the most fundamental properties of quantum mechanics, and is the key resource for quantum information processing (QIP). Bipartite entangled states of identical particles have been generated and studied in several experiments, and post-selected or heralded entangled states involving pairs of photons, single photons and single atoms, or different nuclei in the solid state, have also been produced. Here we use a deterministic quantum logic gate to generate a 'hybrid' entangled state of two trapped-ion qubits held in different isotopes of calcium, perform full tomography of the state produced, and make a test of Bell's inequality with non-identical atoms...
December 17, 2015: Nature
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