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https://www.readbyqxmd.com/read/29778386/ovarian-stimulation-in-infertile-women-treated-with-the-use-of-intrauterine-insemination-a-cohort-study-from-china
#1
Shuo Huang, Rui Wang, Rong Li, Haiyan Wang, Jie Qiao, Ben Willem J Mol
OBJECTIVE: To study the effectiveness of different ovarian stimulation protocols compared with natural cycle treatment in an intrauterine insemination (IUI) program. DESIGN: Retrospective cohort study. SETTING: Large reproductive medicine center. PATIENT(S): Couples with unexplained or mild male-factor infertility. INTERVENTION(S): Couples were treated with the use of natural-cycle IUI, or IUI after ovarian stimulation with the use of clomiphene citrate (CC), letrozole, or gonadotropins...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29778384/association-of-birth-defects-with-the-mode-of-assisted-reproductive-technology-in-a-chinese-data-linkage-cohort
#2
Hui-Ting Yu, Qing Yang, Xiao-Xi Sun, Guo-Wu Chen, Nai-Si Qian, Ren-Zhi Cai, Han-Bing Guo, Chun-Fang Wang
OBJECTIVE: To evaluate the impact of assisted reproductive technology (ART) on the offspring of Chinese population. DESIGN: Retrospective, data-linkage cohort. SETTING: Not applicable. PATIENT(S): Live births resulting from ART or natural conception. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Birth defects coded according to ICD-10. RESULT(S): Births after ART were more likely to be female and multiple births, especially after intracytoplasmic sperm injection (ICSI)...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29775803/assisted-reproductive-technologies-and-imprinting-disorders-results-of-a-study-from-a-french-congenital-malformations-registry
#3
Audrey Uk, Sophie Collardeau-Frachon, Quentin Scanvion, Lucas Michon, Emmanuelle Amar
INTRODUCTION: Assisted Reproductive Technologies (ART) is increasingly used to help infertile couples to have children around the world. A number of studies have been published reporting an increased risk of major malformations in children born following ART, especially an increased incidence of epigenetic diseases (ED). This study aimed to assess the incidence of epigenetic diseases with affected imprinting genes in infants or children from pregnancies obtained through IVF/ICSI compared to infants or children from pregnancies obtained spontaneously...
May 15, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29773523/-consumption-of-free-sugars-and-excess-weight-in-infants-a-longitudinal-study
#4
Cristina Jardí, Núria Aranda, Cristina Bedmar, Blanca Ribot, Irene Elias, Estefania Aparicio, Victoria Arija
INTRODUCTION: The consumption of free sugars has been related to excess weight, with the WHO recommending an intake of <10% of total energy. The aim of this study is to assess the association between the consumption of free sugars at 12 months and the risk of excess weight at 30 months in healthy children. MATERIAL AND METHODS: A longitudinal study was conducted on 81 children followed-up from birth to 30 months. A record was made of the clinical history and anthropometry, at birth, and at 12 and 30 months...
May 14, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29767673/modeling-the-impact-of-folic-acid-fortification-and-supplementation-on-red-blood-cell-folate-concentrations-and-predicted-neural-tube-defect-risk-in-the-united-states-have-we-reached-optimal-prevention
#5
Krista S Crider, Yan Ping Qi, Owen Devine, Sarah C Tinker, Robert J Berry
Background: The US CDC and the Institute of Medicine recommend that women capable of becoming pregnant consume ≥400 µg synthetic folic acid/d to prevent neural tube defects (NTDs). The United States has 3 sources of folic acid: fortified enriched cereal grain products (ECGPs), fortified ready-to-eat (RTE) cereals, and dietary supplements. Objective: Our objectives were as follows: 1) to estimate the usual daily folic acid intake and distributions of red blood cell (RBC) folate concentrations among women consuming folic acid from different sources; 2) to assess the usual daily total folic acid intake associated with optimal RBC folate concentrations for NTD prevention; 3) to predict NTD prevalence; and 4) to estimate the number of preventable folate-sensitive NTDs...
May 14, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29765785/spondylocostal-dysostosis-a-literature-review-and-case-report-with-long-term-follow-up-of-a-conservatively-managed-patient
#6
Brendan R Southam, Adam P Schumaier, Alvin H Crawford
Introduction: Patients with spondylocostal dysostosis (SCD) have congenital spine and rib deformities associated with frequently severe thoracic insufficiency and respiratory compromise. The literature is largely composed of case reports and small cohorts, and there is little information regarding adults with this condition. In this report, we describe the natural history of a conservatively treated patient and include quality-of-life issues such as childbearing, athletic participation, and occupational selection...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29761855/presence-of-scf-cxcl12-double-positive-large-blast-like-cells-at-the-site-of-cutaneous-extramedullary-hematopoiesis
#7
Toshiaki Kogame, Masahiro Hirata, Tatsuki R Kataoka, Judith A Seidel, Chiyuki Ueshima, Miho Matsui, Takashi Nomura, Kenji Kabashima
Extramedullary hematopoiesis (EMH) is observed in the fetal liver and the spleen under physiological conditions, but can rarely occur as pathologic condition after birth. EMH is observed in various anatomical sites in patients with hypoxia-inducing conditions, such as idiopathic myelofibrosis. The nature of the microenvironment for the maintenance of hematopoietic stem cells (HSCs) in EMH is unclear. Recent studies showed that mesenchymal stem/stromal cell (MSC)-derived cells, that can differentiate into various types of cells, play critical roles in the formation of hematopoietic niches...
May 15, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29753950/structure-of-the-lps-o-chain-from-fusobacterium-nucleatum-strain-mjr-7757-b
#8
Evgeny Vinogradov, Frank St Michael, Andrew D Cox
Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis. It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and still births. Cell surface structures of the bacterium could be implicated in pathogenesis. Here we report the following structure of the lipopolysaccharide O-chain of F. nucleatum strain MJR 7757 B:where Lac is (R)-1-carboxyethyl (lactic acid residue); all monosaccharides are in the pyranose form...
April 25, 2018: Carbohydrate Research
https://www.readbyqxmd.com/read/29753684/first-time-mothers-birth-beliefs-preferences-and-actual-birth-a-longitudinal-observational-study
#9
Heidi Preis, Michal Eisner, Rony Chen, Yael Benyamini
PROBLEM: Birth preferences, such as mode and place of birth and other birth options, have important individual and societal implications, yet few studies have investigated the mechanism which predicts a wide range of childbirth options simultaneously. BACKGROUND: Basic beliefs about birth as a natural and as a medical process are both predictive factors for childbirth preferences. Studies investigating birth beliefs, preferences, and actual birth are rare. AIM: To test a predictive model of how these beliefs translate into birth preferences and into actual birth related-options...
May 9, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29752588/a-lateral-to-mesial-organization-of-human-ventral-visual-cortex-at-birth
#10
P Barttfeld, S Abboud, H Lagercrantz, U Adén, N Padilla, A D Edwards, L Cohen, M Sigman, S Dehaene, G Dehaene-Lambertz
In human adults, ventral extra-striate visual cortex contains a mosaic of functionally specialized areas, some responding preferentially to natural visual categories such as faces (fusiform face area) or places (parahippocampal place area) and others to cultural inventions such as written words and numbers (visual word form and number form areas). It has been hypothesized that this mosaic arises from innate biases in cortico-cortical connectivity. We tested this hypothesis by examining functional resting-state correlation at birth using fMRI data from full-term human newborns...
May 11, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29749290/neither-medicine-nor-health-care-staff-members-are-violent-by-nature-obstetric-violence-from-an-interactionist-perspective
#11
Ximena Briceño Morales, Laura Victoria Enciso Chaves, Carlos Enrique Yepes Delgado
This study sought to understand the meaning that women place on the health care practices carried out during labor. We used techniques from Grounded Theory such as coding, categorization, and constant comparison. A total of 18 interviews were conducted with 16 women who had given birth at least once in Colombia. Based on our results, we argue that obstetric violence is an expression of violence during the provision of health care, which occurs in a social environment favoring the development of power relationships between patients and health care staff...
May 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29747156/maternal-areola-ph-a-chemical-basis-for-mother-infant-recognition
#12
Vincenzo Zanardo, Francesca Volpe, Matteo Parotto, Lara Giliberti, Alphonse Simbi, Lorenzo Severino, Gianluca Straface
BACKGROUND: The human female's areolar region is the point of arrival of a natural progression from birth to breastfeeding continuum, supported by numerous functional features. AIMS: The aim of this study was to look more closely into the areola' skin chemical signals that are uniquely important for mother-infant chemoemission, chemoreception, and breastfeeding continuum. STUDY DESIGN: A dermatological study of the areolae and corresponding breast quadrants was undertaken on 71 healthy, at-term women...
May 7, 2018: Early Human Development
https://www.readbyqxmd.com/read/29740943/vanishing-white-matter-a-leukodystrophy-due-to-astrocytic-dysfunction
#13
Marianna Bugiani, Caroline Vuong, Marjolein Breur, Marjo S van der Knaap
VWM is one of the most prevalent leukodystrophies with unique clinical, pathological and molecular features. It mostly affects children, but may develop at all ages, from birth to senescence. It is dominated by cerebellar ataxia and susceptible to stresses that act as factors provoking disease onset or episodes of rapid neurological deterioration possibly leading to death. VWM is caused by mutations in any of the genes encoding the five subunits of the eukaryotic translation initiation factor 2B (eIF2B). Although eIF2B is ubiquitously expressed, VWM primarily manifests as a leukodystrophy with increasing white matter rarefaction and cystic degeneration, meager astrogliosis with no glial scarring and dysmorphic immature astrocytes and increased numbers of oligodendrocyte progenitor cells that are restrained from maturing into myelin-forming cells...
May 2018: Brain Pathology
https://www.readbyqxmd.com/read/29735984/vegetation-diversity-protects-against-childhood-asthma-results-from-a-large-new-zealand-birth-cohort
#14
Geoffrey H Donovan, Demetrios Gatziolis, Ian Longley, Jeroen Douwes
We assessed the association between the natural environment and asthma in 49,956 New Zealand children born in 1998 and followed up until 2016 using routinely collected data. Children who lived in greener areas, as measured by the normalized difference vegetation index, were less likely to be asthmatic: a 1 s.d. increase in normalized difference vegetation index was associated with a 6.0% (95% CI 1.9-9.9%) lower risk of asthma. Vegetation diversity was also protective: a 1 s.d. increase in the number of natural land-cover types in a child's residential meshblock was associated with a 6...
May 7, 2018: Nature Plants
https://www.readbyqxmd.com/read/29735202/zorro-z-omphaloplasty-repair-for-omphalocele
#15
Michel Jean-Luc, Kassir Rani, Harper Luke, Gavage Laurent, Frade Fernanda, Clermidi Pauline, Sauvat Frederique, Ramful Duksha
PURPOSE: To suggest a novel technique for omphalocele closure which uses the circular base of the umbilical cord, thus allowing for a more physiological healing process and natural-looking scar. METHODS: Among 16 neonates operated for omphalocele between 2011 and 2016, 12 were closed with a one-stage procedure using a Z omphaloplasty (ZORRO). Median gestational age was 36.5 weeks; median birth weight was 3210 g. The umbilical arteries were divided and ligated outside the peritoneal cavity above the parietal musculocutaneous plane...
April 6, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29733843/modulation-of-nuclear-factor-%C3%AE%C2%BAb-signaling-and-reduction-of-neural-tube-defects-by-quercetin-3-glucoside-in-embryos-of-diabetic-mice
#16
Chengyu Tan, Fantong Meng, E Albert Reece, Zhiyong Zhao
BACKGROUND: Diabetes mellitus in early pregnancy increases the risk of birth defects in infants. Maternal hyperglycemia stimulates the expression of nitric oxide (NO) synthase 2 (NOS2), which can be regulated by transcription factors of the nuclear factor-κB (NF-κB) family. Increases in reactive nitrogen species (RNS) generate intracellular stress conditions, including nitrosative, oxidative, and endoplasmic reticulum (ER) stresses, and trigger programmed cell death (or apoptosis) in the neural folds, resulting in neural tube defects (NTDs) in the embryo...
May 4, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29731383/-trying-to-give-birth-naturally-was-out-of-the-question-accounting-for-intervention-in-childbirth
#17
Lindsay Cole, Amanda LeCouteur, Rebecca Feo, Hannah Dahlen
PROBLEM: Studies of women's childbirth preferences repeatedly show that natural birth remains highly valued, yet the majority of births involve some form of medical intervention. Reasons for this lack of correspondence have typically been investigated through interviews and focus-groups with women. Relatively little research explores the ways in which women describe their experiences of childbirth outside of such research settings. BACKGROUND: Most maternity services promote woman-centred care, whereby women are encouraged to take active roles in deciding how to give birth...
May 3, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29730962/geographical-origin-delayed-implantation-and-induced-ovulation-explain-reproductive-seasonality-in-the-carnivora
#18
Sandra A Heldstab, Dennis W H Müller, Sereina M Graber, Laurie Bingaman Lackey, Eberhard Rensch, Jean-Michel Hatt, Philipp Zerbe, Marcus Clauss
Patterns of reproductive seasonality in the Carnivora are difficult to study comparatively, due to limited numbers of species for which information is available. Long-term databases of captive populations could overcome this difficulty. We apply a categorical description and a quantitative high-resolution measure (birth peak breadth, the number of days in which 80% of all births occur) based on daily observations in captivity to characterize the degree of reproductive seasonality in the Carnivora for 114 species with on average 1357 births per species...
May 1, 2018: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29729176/-comparative-characteristic-of-functional-gastrocerebral-disorders-in-donors-and-premature-infants
#19
Luydmila V Ignatko, Andriiana O Yankovska, Gabriela G Kavulya, Olena V Debretseni, Kristian O Debretseni, Nataliia M Hema-Bahyna, Agneta V Lenchenko
OBJECTIVE: Introduction: Functional gastrocerebral disorders (FGCD) occupy one of the leading places in the structure of diseases of digestive organs in young children. Functional gastrointestinal disorders are accompanied by various combinations of persistent or recurrent gastrointestinal symptoms without structural or biochemical disorders. They can accompany the normal development of the child and depend on organ's disorders on the background of autonomic dysfunction, psycho-emotional and humoral factors...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29720288/prenatal-malnutrition-and-adult-cognitive-impairment-a-natural-experiment-from-the-1959-1961-chinese-famine
#20
Ping He, Li Liu, J M Ian Salas, Chao Guo, Yunfei Cheng, Gong Chen, Xiaoying Zheng
The current measures of cognitive functioning in adulthood do not indicate a long-term association with prenatal exposure to the Dutch famine. However, whether such association emerges in China is poorly understood. We aimed to investigate the potential effect of prenatal exposure to the 1959-1961 Chinese famine on adult cognitive impairment. We obtained data from the Second National Sample Survey on Disability implemented in thirty-one provinces in 2006, and restricted our analysis to 387 093 individuals born in 1956-1965...
May 3, 2018: British Journal of Nutrition
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