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https://www.readbyqxmd.com/read/28914931/high-speed-2d-raman-imaging-at-elevated-pressures
#1
Naibo Jiang, Paul S Hsu, Jason G Mance, Yue Wu, Mark Gragston, Zhili Zhang, Joseph D Miller, James R Gord, Sukesh Roy
Two-dimensional (2D) Raman scattering at 10 kHz in non-reacting flow mixtures is demonstrated by employing a burst-mode laser with a long-duration pulse of about 70 ns and pulse energy of about 750 mJ at 532 nm. To avoid optical breakdown, the pulse width of the laser was varied in the range of 10-1000 ns. The effects of pulse shape, pulse energy, and harmonic conversion on 2D measurements are also studied. The applications of high-speed, single-shot, 2D imaging of CH4 and H2 jets in N2 at elevated pressures are demonstrated...
September 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28882881/respiratory-manifestations-of-gastro-oesophageal-reflux-in-children
#2
REVIEW
Fernando Maria de Benedictis, Andrew Bush
Gastro-oesophageal reflux disease (GORD) is a complex problem in children. Suspected respiratory manifestations of GORD, such as asthma, chronic cough and laryngitis, are commonly encountered in the paediatric practice, but continue to be entities with more questions than answers. The accuracy of diagnostic tests (ie, pH or pH-impedance monitoring, laryngoscopy, endoscopy) for patients with suspected extraoesophageal manifestations of GORD is suboptimal and therefore whether there is a causal relationship between these conditions remains largely undetermined...
September 7, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28881908/does-physical-activity-protect-against-the-development-of-gastroesophageal-reflux-disease-barrett-s-esophagus-and-esophageal-adenocarcinoma-a-review-of-the-literature-with-a-meta-analysis
#3
S Lam, A R Hart
Physical activity affects the functioning of the gastrointestinal system through both local and systemic effects and may play an important role in reducing the risk of esophageal adenocarcinoma. This review assesses the biological mechanisms and epidemiological evidence for the relationship between physical activity and the development of esophageal adenocarcinoma and its precursor diseases: gastroesophageal reflux disease (GORD) and Barrett's esophagus. A search of PubMed, Medline, Embase, and CINAHL was conducted from their inceptions to 25th March 2017 for analytical studies that examined associations between recreational and/or occupational levels of physical activity and the risk of GORD, Barrett's esophagus, and esophageal adenocarcinoma...
November 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28877531/towards-individualized-tracheobronchial-stents-technical-practical-and-legal-considerations
#4
Lutz Freitag, Martin Gördes, Paul Zarogoulidis, Kaid Darwiche, Daniel Franzen, Faustina Funke, Wolfgang Hohenforst-Schmidt, Hervé Dutau
Stent placement has been established as a standard procedure for treating airway obstructions. Other indications are localized malacias and fistulas. Though many different stents with various diameters and lengths are available, the shapes are hardly ever ideal because of the distorted anatomy in patients with diseased airways. There are technical and legal limitations for customizing purchased airway stents. Individually tailored stents would be preferable. New techniques of additive manufacturing such as 3D printing make it possible to produce optimized stents for a particular patient...
September 7, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28839865/transnasal-endoscopy-no-gagging-no-panic
#5
Clare Parker, Estratios Alexandridis, John Plevris, James O'Hara, Simon Panter
BACKGROUND: Transnasal endoscopy (TNE) is performed with an ultrathin scope via the nasal passages and is increasingly used. This review covers the technical characteristics, tolerability, safety and acceptability of TNE and also diagnostic accuracy, use as a screening tool and therapeutic applications. It includes practical advice from an ear, nose, throat (ENT) specialist to optimise TNE practice, identify ENT pathology and manage complications. METHODS: A Medline search was performed using the terms "transnasal", "ultrathin", "small calibre", "endoscopy", "EGD" to identify relevant literature...
October 2016: Frontline Gastroenterology
https://www.readbyqxmd.com/read/28821410/laparoscopic-redo-anti-reflux-surgery-case-series-of-different-presentations-varied-management-and-their-outcomes
#6
Hari Nageswaran, Ali Haque, Mohammed Zia, Ahmed Hassn
BACKGROUND: A minority of patients undergoing surgery for refractory gastroesophageal reflux disease (GORD) will require revision antireflux surgery ("redo-ARS") for persistent symptoms or complications. Although a repeat minimally invasive procedure for revision may be technically challenging due to post-operative changes, studies are beginning to show favourable data for the laparoscopic approach. METHOD: From a single institution 41 consecutive cases of laparoscopic redo-ARS performed by the same surgeon were classified by mode of presentation to analyse their intra-operative findings, management and post-operative outcomes...
August 15, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28776330/multidimensional-assessment-of-severe-asthma-a-systematic-review-and-meta-analysis
#7
REVIEW
Vanessa L Clark, Peter G Gibson, Grayson Genn, Sarah A Hiles, Ian D Pavord, Vanessa M McDonald
The management of severe asthma is complex. Multidimensional assessment (MDA) of specific traits has been proposed as an effective strategy to manage severe asthma, although it is supported by few prospective studies. We aimed to systematically review the literature published on MDA in severe asthma, to identify the traits included in MDA and to determine the effect of MDA on asthma-related outcomes. We identified 26 studies and classified these based on study type (cohort/cross-sectional studies; experimental/outcome studies; and severe asthma disease registries)...
October 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28761563/the-emerging-role-of-the-eosinophil-and-its-measurement-in-chronic-cough
#8
REVIEW
Mahboobeh H Sadeghi, Alyn H Morice
Although the aetiology of chronic cough in guidelines is clearly stated as asthma and related syndromes, gastro-oesophageal reflux disease (GORD), and upper airways disease, the inflammatory mechanisms underlying these conditions differ. Recent studies on asthma have increasingly focused on its molecular phenotypes instead of clinical characteristics. Here, we proposed the hypothesis that divides cough into two groups; the eosinophilic and neutrophilic. This division will enhance our ability to recognise the type of airway inflammation which, as a consequence will lead us to more targeted and personalized treatment approaches...
2017: Open Respiratory Medicine Journal
https://www.readbyqxmd.com/read/28751897/comparative-agronomic-performance-and-reaction-to-fusarium-wilt-of-lens-culinaris-%C3%A3-l-orientalis-and-l-culinaris-%C3%A3-l-ervoides-derivatives
#9
Mohar Singh, Jai C Rana, Badal Singh, Sandeep Kumar, Deep R Saxena, Ashok Saxena, Aqeel H Rizvi, Ashutosh Sarker
The development of transgressive phenotype in the segregating populations has been speculated to contribute to niche divergence of hybrid lineages, which occurs most frequently at larger genetic distances. Wild Lens species are considered to be more resistant against major biotic and abiotic stresses than that of the cultivated species. In the present study, we assessed the comparative agronomic performance of lentil (Lens culinaris subsp. culinaris) inter-sub-specific (L. culinaris subsp. orientalis) and interspecific (L...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28733768/estimates-of-health-utility-scores-in-chronic-kidney-disease
#10
Nigar Sekercioglu, Bryan Curtis, Sean Murphy, Gord Blackhouse, Brendan Barrett
INTRODUCTION: Coverage decisions in publicly funded healthcare systems require a formal, systematic and transparent assessment process for policies related to distribution of resources. The process is complex and employs multiple types of information, such as clinical effectiveness, costs and health utility scores which are used to produce quality-adjusted life years. The purpose of this study was to create health utility scores for CKD patients within the Canadian population. METHODS: This is a cross-sectional study of CKD patients...
July 21, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28708180/4d-spatiotemporal-evolution-of-combustion-intermediates-in-turbulent-flames-using-burst-mode-volumetric-laser-induced-fluorescence
#11
Benjamin R Halls, Naibo Jiang, Terrence R Meyer, Sukesh Roy, Mikhail N Slipchenko, James R Gord
High-speed (20 kHz rate), volumetric laser-induced-fluorescence imaging of combustion intermediates such as a formaldehyde (CH<sub>2</sub>O) and polycyclic aromatic hydrocarbon (PAH) species is demonstrated for tracking the four-dimensional (4D) evolution of turbulent flames. The third-harmonic, 355 nm output of a burst-mode Nd:YAG laser with a 130 mJ/pulse is expanded to 30 mm diameter for volume illumination of the base region of a methane-hydrogen jet diffusion flame. Eight simultaneous images from different viewing angles are used to collect the resulting fluorescence signal for reconstruction of 200 time-sequential three-dimensional volumes over 10 ms duration...
July 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28702854/gastroesophageal-reflux-disease-and-pulmonary-diseases-associated-with-aspergillosis-is-there-a-connection
#12
Maria N Gamaletsou, David W Denning
INTRODUCTION: We studied the relationship between GORD and allergic bronchopulmonary aspergillosis (ABPA), chronic pulmonary aspergillosis (CPA), or Aspergillus bronchitis. BACKGROUND: Gastroesophageal reflux disease (GORD) is well known to initiate or exacerbate pulmonary inflammatory conditions, inducing bronchial asthma and chronic obstructive lung disease. METHODS: We reviewed four patients referred with elevated Aspergillus serology markers and marked pulmonary symptoms for ABPA, CPA, and Aspergillus bronchitis, and discussed the underlying pathophysiological relationship with GORD...
July 12, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28701952/a-systematic-review-of-the-immune-regulating-and-anticancer-activities-of-pseudolaric-acid-b
#13
REVIEW
Mei-Lun Liu, Dan Sun, Tan Li, Hong Chen
Cortex pseudolaricis, the root bark of Pseudolarix kaempferi Gord, has been used to treat tinea and other skin diseases for the antimicrobial activities in Traditional Chinese Medicine (TCM). Pseudolaric acid B (PAB) has been identified as the major component responsible for the action of C. pseudolaricis. Recently, PAB has been demonstrated to be used as novel treatments for cancer, immune disorders, inflammatory diseases, and immunosuppression. However, the mechanisms through which PAB exerts its properties are not understood well, and little attention in the literature has been given to review its pharmacological activities before...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28689187/acupuncture-for-the-treatment-of-gastro-oesophageal-reflux-disease-a-systematic-review-and-meta-analysis
#14
Jiajie Zhu, Yu Guo, Shan Liu, Xiaolan Su, Yijie Li, Yang Yang, Liwei Hou, Guishu Wang, Jiaxin Zhang, Jiande Jd Chen, Qingguo Wang, Ruhan Wei, Wei Wei
BACKGROUND: Gastro-oesophageal reflux disease (GORD) is one of the most common diseases presenting to gastroenterology clinics. Acupuncture is widely used as a complementary and alternative treatment for patients with GORD. OBJECTIVE: To explore the effectiveness of acupuncture for the treatment of GORD. METHODS: Four English and four Chinese databases were searched through June 2016. Randomised controlled trials investigating the effectiveness of manual acupuncture or electroacupuncture (MA/EA) for GORD versus or as an adjunct to Western medicine (WM) were selected...
July 8, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/28676124/evaluation-of-rational-nonsteroidal-anti-inflammatory-drugs-and-gastro-protective-agents-use-association-rule-data-mining-using-outpatient-prescription-patterns
#15
Oraluck Pattanaprateep, Mark McEvoy, John Attia, Ammarin Thakkinstian
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) and gastro-protective agents should be co-prescribed following a standard clinical practice guideline; however, adherence to this guideline in routine practice is unknown. This study applied an association rule model (ARM) to estimate rational NSAIDs and gastro-protective agents use in an outpatient prescriptions dataset. METHODS: A database of hospital outpatients from October 1st, 2013 to September 30th, 2015 was searched for any of following drugs: oral antacids (A02A), peptic ulcer and gastro-oesophageal reflux disease drugs (GORD, A02B), and anti-inflammatory and anti-rheumatic products, non-steroids or NSAIDs (M01A)...
July 4, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28653691/corrigendum-a-viral-strategy-for-targeting-and-manipulating-interneurons-across-vertebrate-species
#16
Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi, Lihua Guo, Qing Xu, Runpeng Liu, Congyi Lu, Jianhua Chu, Michael C Avery, Mohammad S Rashid, Myungin Baek, Amanda L Jacob, Gordon B Smith, Daniel E Wilson, Georg Kosche, Illya Kruglikov, Tomasz Rusielewicz, Vibhakar C Kotak, Todd M Mowery, Stewart A Anderson, Edward M Callaway, Jeremy S Dasen, David Fitzpatrick, Valentina Fossati, Michael A Long, Scott Noggle, John H Reynolds, Dan H Sanes, Bernardo Rudy, Guoping Feng, Gord Fishell
No abstract text is available yet for this article.
June 27, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28653689/addendum-a-viral-strategy-for-targeting-and-manipulating-interneurons-across-vertebrate-species
#17
Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi, Lihua Guo, Qing Xu, Runpeng Liu, Congyi Lu, Jianhua Chu, Michael C Avery, Mohammad S Rashid, Myungin Baek, Amanda L Jacob, Gordon B Smith, Daniel E Wilson, Georg Kosche, Illya Kruglikov, Tomasz Rusielewicz, Vibhakar C Kotak, Todd M Mowery, Stewart A Anderson, Edward M Callaway, Jeremy S Dasen, David Fitzpatrick, Valentina Fossati, Michael A Long, Scott Noggle, John H Reynolds, Dan H Sanes, Bernardo Rudy, Guoping Feng, Gord Fishell
No abstract text is available yet for this article.
June 27, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28600380/cohort-profile-the-nordic-antireflux-surgery-cohort-nordasco
#18
John Maret-Ouda, Karl Wahlin, Miia Artama, Nele Brusselaers, Martti Färkkilä, Elsebeth Lynge, Fredrik Mattsson, Eero Pukkala, Pål Romundstad, Laufey Tryggvadóttir, My von Euler-Chelpin, Jesper Lagergren
PURPOSE: To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. PARTICIPANTS: Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964-2014 (with various start and end years in different countries)...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28516204/a-novel-dynamic-statistical-model-for-predicting-patient-satisfaction-with-fundoplication-based-on-pre-operative-symptom-patterns
#19
B L Woodham, R Meng, R H Roberts
BACKGROUND: Fundoplication provides excellent control of gastro-oesophageal reflux disease (GORD), but there remain a number of unsatisfied patients who have proven difficult to identify pre-operatively. We hypothesised that pre-operative symptom patterns can predict of the risk of post-operative dissatisfaction. METHODS: Pre-operative symptoms and post-operative satisfaction were measured using standardised questionnaires along with routine investigations. These data were used to calculate our novel pre-operative risk of dissatisfaction (PROD) score...
May 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28506663/cough-associated-with-gastro-oesophageal-reflux-disease-gord-japanese-experience
#20
REVIEW
Akio Niimi
Differences in the aetiology as well as patient background of chronic cough have been recognised among US, UK, and Japan. One of the marked differences has been the prevalence of gastro-oesophageal reflux disease (GORD), which has been one of the top three causes in Western countries. It was indeed uncommon or rare in Japan, but, with the increasing prevalence of GOR itself, chronic cough associated with GORD seems to have become more common. In this article, cough associated with GORD will be reviewed based on literature and our Japanese experience...
May 12, 2017: Pulmonary Pharmacology & Therapeutics
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