keyword
https://read.qxmd.com/read/38498000/mass-spectrometry-based-method-to-measure-aflatoxin-b-1-dna-adducts-in-formalin-fixed-paraffin-embedded-tissues
#1
JOURNAL ARTICLE
Medjda Bellamri, Lihua Yao, Rachana Tomar, Vladimir Vartanian, Carmelo J Rizzo, Michael P Stone, John D Groopman, R Stephen Lloyd, Robert J Turesky
Aflatoxin B1 (AFB1 ) is a potent human liver carcinogen produced by certain molds, particularly Aspergillus flavus and Aspergillus parasiticus , which contaminate peanuts, corn, rice, cottonseed, and ground and tree nuts, principally in warm and humid climates. AFB1 undergoes bioactivation in the liver to produce AFB1 - exo -8,9-epoxide, which forms the covalently bound cationic AFB1 - N 7-guanine (AFB1 -N 7-Gua) DNA adduct. This adduct is unstable and undergoes base-catalyzed opening of the guanine imidazolium ring to form two ring-opened diastereomeric 8,9-dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)-9-hydroxy-aflatoxin B1 (AFB1 -FapyGua) adducts...
March 18, 2024: Chemical Research in Toxicology
https://read.qxmd.com/read/38497778/weaknesses-in-the-continuity-of-care-for-preterm-infants-discharged-from-the-neonatal-unit
#2
JOURNAL ARTICLE
Mariana Camargo Tanaka, Fabiane Blanco Silva Bernardino, Patrícia Pinto Braga, Lidiane Cristina da Silva Alencastro, Maria Aparecida Munhoz Gaíva, Cláudia Silveira Viera
OBJECTIVE: To identify weaknesses in the continuity of care for preterm infants discharged from a neonatal unit, based on the perspective of professionals in the family health strategy. METHOD: Qualitative research, carried out with 16 professionals from four health regions in a capital city in the center-west of Brazil. Data collection took place from October to December 2020, through semi-structured, individual, and in-person interviews. Data underwent content analysis, supported by the concept of continuity of care...
2024: Revista da Escola de Enfermagem da U S P
https://read.qxmd.com/read/38497181/intraventricular-hemorrhage-and-related-hydrocephalus-patients-demographics-in-a-university-hospital-nicu-single-center-data
#3
JOURNAL ARTICLE
Gulden Demirci Otluoglu, Semra Isik, Berkay Paker, Orkun Koban, Teyyub Hasanov, Akin Akakin, Zafer Orkun Toktas, Baran Yilmaz, Ali Haydar Turhan
AIM: To analyze the demographic and clinical data of preterm or low birth weight newborns with periventricular hemorrhage. MATERIAL AND METHODS: This retrospective study analyzed patients admitted to the neonatal intensive care unit of a Bahcesehir University School of Medicine-Affiliated Hospital due to preterm birth or low birth weight between June 1, 2012, and April 30, 2021. Categorical values were evaluated by Pearson chi-square or Fisher's exact test. The Mann-Whitney U test compared continuous values between the groups...
2024: Turkish Neurosurgery
https://read.qxmd.com/read/38497079/impact-of-oil-massage-on-newborn-behavioural-responses-in-rural-india
#4
JOURNAL ARTICLE
B Mahalakshmi, Patel Urvi Sureshbhai, Amita Shilpa Gottlieb, N Sivasubramanian, Gnanadesigan Ekambaram, Ravi Kant
The initial weeks of a newborn's life are marked by rapid physiological and behavioural adjustments as the infant adapts to the external environment. This critical period necessitates attentive care, prompting exploration into traditional practices such as oil massage, which holds cultural significance and is believed to enhance neonatal well-being. Despite its prevalence, empirical evidence supporting the efficacy of oil massage remains limited. This study, conducted in a rural setting, aims to bridge traditional practices with evidence-based care, exploring the impact of oil massage on newborn behavioural responses...
2024: Bioinformation
https://read.qxmd.com/read/38496374/too-much-salt-to-my-taste-an-entity-to-think-about-in-neonatal-hypernatremia-a-case-report-and-review-of-the-literature
#5
Marwa El Masri, Lidiya Samotiy-Hanna, Ramy Ghabril, Yolla Nassif, Dany Al Hamod
In exclusively breastfed newborns, hypernatremic dehydration is associated with a free water deficit secondary to insufficient fluid intake. Failure of newborns to regain their birth weight by the 10th day of life should be investigated urgently. In this report, we present a case of a 2 -week-old girl who presented to our institution for 30% weight loss and was found to have severe hypernatremic dehydration associated with acute renal failure (creatinine 4 mg/dL). Upon further investigation, the breast milk sodium content was found to be extremely elevated (90 mEq/L)...
2024: Case Reports in Pediatrics
https://read.qxmd.com/read/38496210/biliary-atresia-in-preterm-infants-a-single-center-experience-and-review-of-literature
#6
JOURNAL ARTICLE
Federico Beati, Antonella Mosca, Andrea Pietrobattista, Daniela Liccardo, Sara Ronci, Lidia Monti, Paola Francalanci, Marco Spada, Giuseppe Maggiore, Pietro Bagolan, Fabio Fusaro
INTRODUCTION: The diagnosis of biliary atresia (BA) remains challenging, and there is still uncertainty regarding the optimal time to perform a Kasai portoenterostomy (KPE). Little is known about the difficulties in the diagnosis and outcomes of BA in preterm infants (PBA). This study, which represents the first Italian report of preterm infants with BA, aims to describe a single-center experience of BA in preterm newborns. METHODS: We retrospectively reviewed all infants consecutively diagnosed with BA who underwent a Kasai procedure at the Bambino Gesù Children's Hospital between January 1998 and December 2021...
2024: Frontiers in Surgery
https://read.qxmd.com/read/38496125/effects-of-the-covid-19-pandemic-on-breastfeeding-initiation-and-duration-a-retrospective-cohort-study
#7
JOURNAL ARTICLE
Mariana M Meneses, Catarina Freitas, Joana Machado Morais, Maria S Dias, Cláudia Ferraz, Sara Peixoto
INTRODUCTION AND OBJECTIVES: Several studies support the health benefits of breastfeeding for both the mother and the newborn. However, a significant number of mothers discontinue breastfeeding within the first six months of childbirth, with several factors influencing breastfeeding adherence. The purpose of this study is to assess the impact of the COVID-19 pandemic on the prevention of mother-to-newborn infection transmission, breastfeeding patterns and duration, and the incidence of other infections during the first year of life...
February 2024: Curēus
https://read.qxmd.com/read/38496090/efficacy-and-safety-of-oral-euphorbia-prostrata-tablet-and-topical-cream-in-the-management-of-hemorrhoids-during-pregnancy-results-from-a-prospective-multicenter-study
#8
JOURNAL ARTICLE
Ashwin Porwal, Paresh Gandhi, Nameeta Mokashi-Bhalerao, Nilesh Borkar, Kunal Khobragade
This is a non-randomized, open-label, prospective single-arm interventional multicentric study conducted between 2021 and 2022 at three different centers situated in Pune, India. It was conducted to evaluate the efficacy and safety of the Sitcom® tablet ( Euphorbia prostrata 100 mg) once daily and Sitcom® cream ( Euphorbia prostrata 1%w/w) for 14 days in hemorrhoids during pregnancy. The endpoints were to assess hemorrhoidal symptoms relief during the follow-up periods (one, two, four, and eight weeks and 30 days postpartum), relapse of symptoms, improvement in the disease condition at week two and 30 days postpartum, and adverse events...
February 2024: Curēus
https://read.qxmd.com/read/38496087/megacystis-microcolon-intestinal-hypoperistalsis-syndrome-a-case-report-of-an-uncommon-condition
#9
Marcia Mejia, Mónica Royero Arias, Jonathan Pimiento Figueroa, Walter Romero Espitia
The megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS), also known as Berdon syndrome, is a rare congenital condition that falls within the spectrum of visceral myopathies. It is characterized by the presence of megacystis, microcolon, and hypoperistalsis, which are secondary to gastrointestinal and urinary system dysmotility. It is frequently associated with other alterations in the gastrointestinal and genitourinary tracts. Although it is possible to make the diagnosis in the prenatal period, most cases are diagnosed after birth through genetic and imaging studies...
February 2024: Curēus
https://read.qxmd.com/read/38496078/perinatal-outcomes-of-newborns-of-covid-19-infected-pregnant-women-an-updated-systematic-review-and-meta-analysis
#10
REVIEW
Khaled El-Atawi, Muzafar Gani Abdul Wahab, Yasser Elsayed, Maysa Saleh
In this systematic review and meta-analysis, we aimed to review the characteristics and outcomes of the newborns of Coronavirus disease 2019 (COVID-19) infected pregnant women. We conducted an online bibliographic search using the following electronic databases: MEDLINE via PubMed, Scopus, Web of Science, and Cochrane Central. Studies were deemed eligible if they recruited newborns from mothers with confirmed COVID-19 and reported the perinatal outcomes of neonatal COVID-19 cases. A total of 20 studies were included...
February 2024: Curēus
https://read.qxmd.com/read/38496015/newborn-screening-for-g6pd-deficiency-in-hefei-fuyang-and-anqing-china-prevalence-cut-off-value-variant-spectrum
#11
JOURNAL ARTICLE
Hui Li, Yah Ch'ih, Meiling Li, Yulei Luo, Hao Liu, Junyang Xu, Wangsheng Song, Qingqing Ma, Ziyu Shao
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive Mendelian genetic disorder characterized by neonatal jaundice and hemolytic anemia, affecting more than 400 million people worldwide. The purpose of this research was to investigate prevalence rates of G6PD deficiency and to evaluate and establish specific cut-off values in early prediction of G6PD deficiency by regions (HeFei, FuYang, AnQing) on different seasons, as well as to investigate the frequencies of G6PD gene mutations among three regions mentioned above...
January 25, 2024: Journal of Medical Biochemistry
https://read.qxmd.com/read/38495518/accuracy-of-prenatal-and-postnatal-biomarkers-for-estimating-gestational-age-a-systematic-review-and-meta-analysis
#12
JOURNAL ARTICLE
Elizabeth Bradburn, Agustin Conde-Agudelo, Nia W Roberts, Jose Villar, Aris T Papageorghiou
BACKGROUND: Knowledge of gestational age (GA) is key in clinical management of individual obstetric patients, and critical to be able to calculate rates of preterm birth and small for GA at a population level. Currently, the gold standard for pregnancy dating is measurement of the fetal crown rump length at 11-14 weeks of gestation. However, this is not possible for women first presenting in later pregnancy, or in settings where routine ultrasound is not available. A reliable, cheap and easy to measure GA-dependent biomarker would provide an important breakthrough in estimating the age of pregnancy...
April 2024: EClinicalMedicine
https://read.qxmd.com/read/38495224/integration-of-a-respiratory-function-monitor-into-newborn-positive-pressure-ventilation-training-development-of-a-standardised-training-intervention
#13
JOURNAL ARTICLE
C M Ni Chathasaigh, L Smiles, E O'Currain, A E Curley
OBJECTIVE: One in twenty newborns require resuscitation with positive pressure ventilation (PPV) at birth. Newborn face mask ventilation is often poorly performed. To address this, the potential role of respiratory function monitors (RFM) in newborn resuscitation training has been highlighted. The objective of this study was to develop a standardised training intervention on newborn PPV using an RFM with a simple visual display to identify and correct suboptimal ventilations. METHODS: We adapted the framework from a simulation development guideline to create a hands-on intervention on newborn PPV using an RFM with simple visual feedback (Monivent NeoTraining)...
June 2024: Resuscitation plus
https://read.qxmd.com/read/38494246/role-of-gene-interactions-in-the-pathophysiology-of-skeletal-dysplasias-a-case-report-in-colombia
#14
JOURNAL ARTICLE
Nathalie Yepes Madrid, Lina Johanna Moreno Giraldo
BACKGROUND: Genome association studies have shown that gene-gene interactions or epistasis play a crucial role in identifying the etiology, prognosis, and treatment response of many complex diseases beyond their main effects. Skeletal dysplasias are a heterogeneous group of congenital bone and cartilage disorders with a genetic and gen-gen interaction etiology. The current classification of skeletal dysplasias distinguishes 461 diseases in 42 groups, and the incidence of all skeletal dysplasias is more than 1 in every 5000 newborns...
March 2024: Journal, Genetic Engineering & Biotechnology
https://read.qxmd.com/read/38494069/posttraumatic-stress-disorder-2-months-after-cesarean-delivery-a-multicenter-prospective-study
#15
JOURNAL ARTICLE
Alizée Froeliger, Catherine Deneux-Tharaux, Lola Loussert, Hugo Madar, Loïc Sentilhes
BACKGROUND: The prevalence and risk factors of posttraumatic stress disorder (PTSD) after cesarean delivery, outside high-risk contexts, remain unclear OBJECTIVE: To assess posttraumatic stress disorder prevalence and risk factors at 2 months postpartum among a general population of women with cesarean delivery. STUDY DESIGN: Prospective ancillary cohort study of the Tranexamic Acid for Preventing Postpartum Hemorrhage after Cesarean Delivery (TRAAP2) trial, conducted in 27 French hospitals in 2018-2020 and enrolling women expected to undergo cesarean delivery before or during labor at 34 or more weeks of gestation...
March 15, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38493709/enterovirus-and-parechovirus-meningoencephalitis-in-infants-a-ten-year-prospective-observational-study-in-a-neonatal-intensive-care-unit
#16
JOURNAL ARTICLE
Carlo Pietrasanta, Andrea Ronchi, Laura Bassi, Agnese De Carli, Luca Caschera, Francesco Maria Lo Russo, Beatrice Letizia Crippa, Silvia Pisoni, Riccardo Crimi, Giacomo Artieri, Laura Pellegrinelli, Robertino Dilena, Giorgio Conte, Fabio Mosca, Monica Fumagalli, Lorenza Pugni
BACKGROUND: Non-polio enteroviruses (EV) and human parechoviruses (HPeV) are known etiological agents of meningoencephalitis in neonates. However, reports of neuroradiological findings and neurodevelopmental outcomes in this population are scarce. OBJECTIVES: to describe clinical characteristics, neuroradiological findings and, in a subset of patients, neurodevelopmental outcomes in a cohort of infants with EV or HPeV meningoencephalitis within 60 days of life. STUDY DESIGN: clinical/laboratory data, neuroradiological findings (cranial ultrasound, cUS, brain magnetic resonance imaging, MRI), and neurodevelopmental outcomes assessed by Ages and Stages Questionnaires - third edition were prospectively collected...
March 5, 2024: Journal of Clinical Virology
https://read.qxmd.com/read/38493431/evaluation-of-the-protective-and-therapeutic-effects-of-extra-virgin-olive-oil-rich-in-phenol-in-experimental-model-of-neonatal-necrotizing-enterocolitis-by-clinical-disease-score-%C3%A4-nflammation-apoptosis-and-oxidative-stress-markers
#17
JOURNAL ARTICLE
Mustafa Tuşat, Recep Eroz, Ferhan Bölükbaş, Erkan Özkan, Hüseyin Erdal
BACKGROUND AND AIM: Necrotizing Enterocolitis (NEC) is an inflammation-associated ischemic necrosis of the intestine. To investigate the effects of extra virgin olive oil (EVOO) on inflammation, oxidative stress, apoptosis, and histological changes in NEC-induced newborn rats. MATERIALS AND METHODS: 24 rats were randomly divided into three groups: control, NEC and NEC + EVOO. NEC induction was performed using hypoxia-hyperoxia, formula feeding, and cold stress...
March 17, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38493255/effects-of-postnatal-corticosteroids-on-lung-development-in-newborn-animals-a-systematic-review
#18
Irene M Lok, Kimberley E Wever, Roos J S Vliegenthart, Wes Onland, Anton H van Kaam, Minke van Tuyl
BACKGROUND: Postnatal systemic corticosteroids reduce the risk of bronchopulmonary dysplasia but the effect depends on timing, dosing, and type of corticosteroids. Animal studies may provide valuable information on these variable effects. This systematic review summarizes the effects of postnatal systemic corticosteroids on lung development in newborn animals. METHODS: A systematic search was performed in PubMed and Embase in December 2022. The protocol was published on PROSPERO (CRD42021177701)...
March 16, 2024: Pediatric Research
https://read.qxmd.com/read/38493094/awareness-and-healthcare-seeking-behavior-of-neonatal-danger-signs-and-predictor-variables-among-mothers-caregivers-in-four-developing-regional-state-of-ethiopia
#19
JOURNAL ARTICLE
Nagasa Dida, Lonsako Abute, Tariku Dejene, Tolasa Yadate, Temesgen Geleta, Rachana Sharma, Hnin Su Mon, Tesfaye Simireta, Hailemariam Addisu
INTRODUCTION: Mothers/caregivers should be aware of a newborn's danger signs and promptly seek medical attention. Hence, this study assessed mothers'/caregivers' awareness, healthcare seeking behaviors for neonatal danger signs and their determinants in the developing regional state of Ethiopia. METHODS: A community-based cross-sectional study was employed among mothers/caregivers of neonates in the developing regional state of Ethiopia. The sample was determined in collaboration with the Central Statistics Agency of Ethiopia...
March 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38493088/postnatal-care-and-acceptability-of-emollient-therapy-in-very-low-birthweight-infants-in-harare-zimbabwe-a-qualitative-analysis
#20
JOURNAL ARTICLE
Alexa Hui, Gwendoline Chimhini, Margaret Saungweme, Dorah Kaisi, Elisabeth Munetsi, Hilda A Mujuru, Gary L Darmstadt
BACKGROUND: Preterm birth (birth before 37 completed weeks of pregnancy) is the leading cause of neonatal and child under-five mortality globally, both of which are highest regionally in sub-Saharan Africa. The skin barrier plays a critical role in neonatal health and increasing evidence supports the use of topical emollient therapy to promote postnatal growth and reduce hospital-acquired infections in preterm infants. The World Health Organization (WHO) currently recommends emollient therapy in preterm or low birthweight infants globally but calls for further research on impacts of emollient use, especially in Africa...
March 16, 2024: BMC Pediatrics
keyword
keyword
2465
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.