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https://www.readbyqxmd.com/read/29504954/utility-of-novel-autoantibodies-in-the-diagnosis-of-sj%C3%A3-gren-s-syndrome-among-patients-with-dry-eye
#1
Sezen Karakus, Alan N Baer, Devika Agrawal, Merve Gurakar, Robert W Massof, Esen K Akpek
PURPOSE: To investigate the value of 3 novel autoantibodies [salivary protein 1 (SP1), carbonic anhydrase 6 (CA6), and parotid secretory protein (PSP)] in differentiating Sjögren's syndrome (SS)-related dry eye from non-SS dry eye. METHODS: Forty-six dry eye patients with SS (SS dry eye), 14 dry eye patients without SS (non-SS dry eye), and 25 controls were included. The 2012 American College of Rheumatology classification criteria were used for the diagnosis of SS...
April 2018: Cornea
https://www.readbyqxmd.com/read/29485207/clinical-outcomes-of-low-vision-rehabilitation-delivered-by-a-mobile-clinic
#2
Micaela Gobeille, Alexis Malkin, Richard Jamara, Nicole C Ross
PURPOSE: This prospective cohort study examined clinical outcomes of low vision rehabilitation (LVR) delivered by a mobile clinic. METHODS: Participants were recruited from those scheduled for mobile clinic LVR and met the United States definition of legal blindness. Participants completed the Massof Activity Inventory (AI) before LVR, 3 months post-LVR, and 1 year post-LVR. Change scores and measures of clinical effect (i.e. Cohen's effect size and minimum clinically important difference, MCID) were calculated for each time point and compared...
March 2018: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29098289/estimates-of-incidence-and-prevalence-of-visual-impairment-low-vision-and-blindness-in-the-united-states
#3
Tiffany Chan, David S Friedman, Chris Bradley, Robert Massof
Importance: Updated estimates of the prevalence and incidence rates of low vision and blindness are needed to inform policy makers and develop plans to meet the future demands for low vision rehabilitation services. Objective: To provide updated estimates of the incidence and prevalence of low vision and blindness in the United States. Design, Setting, and Participants: Visual acuity measurements as a function of age from the 2007-2008 National Health and Nutrition Examination Survey, with representation of racial and ethnic groups, were used to estimate the prevalence and incidence of visual impairments...
January 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28573075/development-of-the-ultra-low-vision-visual-functioning-questionnaire-ulv-vfq
#4
Pamela E Jeter, Collin Rozanski, Robert Massof, Olukemi Adeyemo, Gislin Dagnelie
PURPOSE: To develop and psychometrically evaluate a visual functioning questionnaire (VFQ) in an ultra-low vision (ULV) population. METHODS: Questionnaire items, based on visual activities self-reported by a ULV population, were categorized by functional visual domain (e.g., mobility) and visual aspect (e.g., contrast) to ensure a representative distribution. In Round 1, an initial set of 149 items was generated and administered to 90 participants with ULV (visual acuity [VA] ≤ 20/500; mean [SD] age 61 [15] years), including six patients with a retinal implant...
May 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28573074/living-with-ultra-low-vision-an-inventory-of-self-reported-visually-guided-activities-by-individuals-with-profound-visual-impairment
#5
Olukemi Adeyemo, Pamela E Jeter, Collin Rozanski, Ellen Arnold, Lauren A Dalvin, Bonnielin Swenor, Gislin Dagnelie
PURPOSE: To understand how individuals with profound visual impairment (ultra-low vision, ULV) use their remaining vision. METHODS: Forty-six participants with ULV (visual acuity ≤ 200/500 in the better seeing eye) were divided into nine focus groups (4-6 individuals per group) and met either in person (n = 2) or over the phone (n = 7). Discussions were guided by the Massof Activity Inventory. Audio recordings were transcribed and analyzed for visual activities that were then classified along two visual categorizations - functional domains and visual aspects...
May 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28371261/visual-and-health-outcomes-measured-with-the-activity-inventory-and-the-eq-5d-in-visual-impairment
#6
MULTICENTER STUDY
Antonio Filipe Macedo, Pedro Lima Ramos, Laura Hernandez-Moreno, Joana Cima, António M G Baptista, Ana Patricia Marques, Robert Massof, Rui Santana
PURPOSE: Generic instruments to assess health utilities can be used to express the burden of health problems in widely used indexes. That is in contrast with what can be obtained with condition-specific instruments, outcomes are very specific and difficult to compare across conditions. The purpose of this study was to assess health and visual outcomes and its determinants in patients with visual impairment (VI) using the EQ-5D-3L and the Activity Inventory (AI). METHODS: Participants were recruited in different hospitals during the PCVIP-study...
December 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28273318/functional-outcomes-of-the-low-vision-depression-prevention-trial-in-age-related-macular-degeneration
#7
RANDOMIZED CONTROLLED TRIAL
Ashley D Deemer, Robert W Massof, Barry W Rovner, Robin J Casten, Catherine V Piersol
Purpose: To compare the efficacy of behavioral activation (BA) plus low vision rehabilitation with an occupational therapist (OT-LVR) with supportive therapy (ST) on visual function in patients with age-related macular degeneration (AMD). Methods: Single-masked, attention-controlled, randomized clinical trial with AMD patients with subsyndromal depressive symptoms (n = 188). All subjects had two outpatient low vision rehabilitation optometry visits, then were randomized to in-home BA + OT-LVR or ST...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28045563/multivariable-regression-model-of-the-euroqol-5-dimension-questionnaire-in-patients-seeking-outpatient-low-vision-rehabilitation
#8
Alexis G Malkin, Judith E Goldstein, Robert W Massof
PURPOSE: To understand the source of between-person variance in baseline health utilities estimated from EuroQol 5-dimension questionnaire (EQ-5D) responses of a representative sample of the US low vision outpatient population prior to rehabilitation. METHODS: A prospective, observational study of 779 new low vision patients at 28 clinic centers in the US. The EQ-5D, Activity Inventory (AI), Telephone Interview for Cognitive Status (TICS), Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) physical functioning component, and Geriatric Depression Scale (GDS) were administered by telephone interview prior to rehabilitation...
June 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27978569/outcomes-of-the-veterans-affairs-low-vision-intervention-trial-ii-lovit-ii-a-randomized-clinical-trial
#9
Joan A Stelmack, X Charlene Tang, Yongliang Wei, Denise Thomas Wilcox, Timothy Morand, Karen Brahm, Scott Sayers, Robert W Massof
Importance: Randomized clinical trials are needed to compare effectiveness and cost-effectiveness of different low-vision (LV) programs. Objective: To determine the value of adding LV rehabilitation with a therapist compared with LV services without intervention. Design, Setting, and Participants: A randomized clinical trial was conducted from September 27, 2010, to July 31, 2014, of 323 veterans with macular diseases and best-corrected distance visual acuity (BCDVAbetter-eye) of 20/50 to 20/200...
December 15, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/26163943/equating-visual-function-scales-to-facilitate-reporting-of-medicare-functional-g-code-severity-complexity-modifiers-for-low-vision-patients
#10
Tiffany L Chan, Monica S Perlmutter, Melva Andrews, Janet S Sunness, Judith E Goldstein, Robert W Massof
OBJECTIVE: To present a method of estimating and equating scales across functional assessment instruments that appropriately represents changes in a patient's functional ability and can be meaningfully mapped to changes in Medicare G-code severity modifiers. DESIGN: Previously published measures of patients' overall visual ability, estimated from low-vision patient responses to 7 different visual function rating scale questionnaires, are equated and mapped onto Medicare G-code severity modifiers...
October 2015: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/25856370/clinically-meaningful-rehabilitation-outcomes-of-low-vision-patients-served-by-outpatient-clinical-centers
#11
MULTICENTER STUDY
Judith E Goldstein, Mary Lou Jackson, Sandra M Fox, James T Deremeik, Robert W Massof
IMPORTANCE: To facilitate comparative clinical outcome research in low vision rehabilitation, we must use patient-centered measurements that reflect clinically meaningful changes in visual ability. OBJECTIVE: To quantify the effects of currently provided low vision rehabilitation (LVR) on patients who present for outpatient LVR services in the United States. DESIGN, SETTING, AND PARTICIPANTS: Prospective, observational study of new patients seeking outpatient LVR services...
July 2015: JAMA Ophthalmology
https://www.readbyqxmd.com/read/25813453/comparing-the-impact-of-refractive-and-nonrefractive-vision-loss-on-functioning-and-disability-the-salisbury-eye-evaluation
#12
COMPARATIVE STUDY
Nazlee Zebardast, Bonnielin K Swenor, Suzanne W van Landingham, Robert W Massof, Beatriz Munoz, Sheila K West, Pradeep Y Ramulu
PURPOSE: To compare the effects of uncorrected refractive error (URE) and nonrefractive visual impairment (VI) on performance and disability measures. DESIGN: Cross-sectional, population-based study. PARTICIPANTS: A total of 2469 individuals with binocular presenting visual acuity (PVA) of ≥ 20/80 who participated in the first round of the Salisbury Eye Evaluation study. METHODS: The URE was defined as binocular PVA of ≤ 20/30, improving to >20/30 with subjective refraction...
June 2015: Ophthalmology
https://www.readbyqxmd.com/read/25073745/visual-ability-of-patients-seeking-outpatient-low-vision-services-in-the-united-states
#13
MULTICENTER STUDY
Judith E Goldstein, Melissa W Chun, Donald C Fletcher, James T Deremeik, Robert W Massof
IMPORTANCE: Most patients with low vision are elderly and have functional limitations from other health problems that could add to the functional limitations caused by their visual impairments. OBJECTIVE: To identify factors that contribute to visual ability measures in patients who present for outpatient low vision rehabilitation (LVR) services. DESIGN, SETTING, AND PARTICIPANTS: As part of a prospective, observational study of new patients seeking outpatient LVR, 779 patients from 28 clinical centers in the United States were enrolled in the Low Vision Rehabilitation Outcomes Study (LVROS) from April 25, 2008, through May 2, 2011...
October 2014: JAMA Ophthalmology
https://www.readbyqxmd.com/read/25052992/reading-ability-and-reading-engagement-in-older-adults-with-glaucoma
#14
Angeline M Nguyen, Suzanne W van Landingham, Robert W Massof, Gary S Rubin, Pradeep Y Ramulu
PURPOSE: We evaluated the impact of glaucoma-related vision loss on reading ability and reading engagement in 10 reading activities. METHODS: A total of 63 glaucoma patients and 59 glaucoma suspect controls self-rated their level of reading difficulty for 10 reading items, and responses were analyzed using Rasch analysis to determine reading ability. Reading engagement was assessed by asking subjects to report the number of days per week they engaged in each reading activity...
August 2014: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/25016366/low-vision-depression-prevention-trial-in-age-related-macular-degeneration-a-randomized-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Barry W Rovner, Robin J Casten, Mark T Hegel, Robert W Massof, Benjamin E Leiby, Allen C Ho, William S Tasman
PURPOSE: To compare the efficacy of behavior activation (BA) + low vision rehabilitation (LVR) with supportive therapy (ST) + LVR to prevent depressive disorders in patients with age-related macular degeneration (AMD). DESIGN: Single-masked, attention-controlled, randomized, clinical trial with outcome assessment at 4 months. PARTICIPANTS: Patients with AMD and subsyndromal depressive symptoms attending retina practices (n = 188). INTERVENTIONS: Before randomization, all subjects had 2 outpatient LVR visits, and were then randomized to in-home BA+LVR or ST+LVR...
November 2014: Ophthalmology
https://www.readbyqxmd.com/read/24768243/characterizing-functional-complaints-in-patients-seeking-outpatient-low-vision-services-in-the-united-states
#16
Jamie C Brown, Judith E Goldstein, Tiffany L Chan, Robert Massof, Pradeep Ramulu
PURPOSE: To characterize functional complaints of new low-vision rehabilitation patients. DESIGN: Prospective observational study. PARTICIPANTS: The Low Vision Rehabilitation Outcomes Study recruited 819 patients between 2008 and 2011 from 28 clinical centers in the United States. METHODS: New patients referred for low-vision rehabilitation were asked, "What are your chief complaints about your vision?" before their appointment...
August 2014: Ophthalmology
https://www.readbyqxmd.com/read/24472499/fear-of-falling-in-age-related-macular-degeneration
#17
Suzanne W van Landingham, Robert W Massof, Emilie Chan, David S Friedman, Pradeep Y Ramulu
BACKGROUND: Prior studies have shown age-related macular degeneration (AMD) to be associated with falls. The purpose of this study is to determine if (AMD) and AMD-related vision loss are associated with fear of falling, an important and distinct outcome. METHODS: Sixty-five persons with AMD with evidence of vision loss in one or both eyes and 60 glaucoma suspects with normal vision completed the University of Illinois at Chicago Fear of Falling questionnaire. Responses were Rasch analyzed...
January 28, 2014: BMC Ophthalmology
https://www.readbyqxmd.com/read/23884309/measuring-the-patient-s-perspective
#18
EDITORIAL
Konrad Pesudovs, Julie Ratcliffe, Ecosse L Lamoureux, Mats Lundström, Robert W Massof, Gary S Rubin
No abstract text is available yet for this article.
August 2013: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/23873036/comparison-of-clinician-predicted-to-measured-low-vision-outcomes
#19
COMPARATIVE STUDY
Tiffany L Chan, Judith E Goldstein, Robert W Massof
PURPOSE: To compare low-vision rehabilitation (LVR) clinicians' predictions of the probability of success of LVR with patients' self-reported outcomes after provision of usual outpatient LVR services and to determine if patients' traits influence clinician ratings. METHODS: The Activity Inventory (AI), a self-report visual function questionnaire, was administered pre-and post-LVR to 316 low-vision patients served by 28 LVR centers that participated in a collaborative observational study...
August 2013: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/23873035/interpretation-of-low-vision-rehabilitation-outcome-measures
#20
Robert W Massof, Joan A Stelmack
PURPOSE: This article presents a theoretical interpretation of patient-reported outcomes of low-vision rehabilitation (LVR) using rating scale questionnaires and uses previously published results of LVR outcome studies to illustrate theoretical points and validate assumptions. THEORY: Patients' judgments of the difficulty they have performing tasks are interpreted as magnitude estimates of their functional reserve for each task, which is the difference between their visual ability and the visual ability demanded by the task...
August 2013: Optometry and Vision Science: Official Publication of the American Academy of Optometry
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