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https://www.readbyqxmd.com/read/28239999/glioblastoma-multiforme-a-review-of-its-epidemiology-and-pathogenesis-through-clinical-presentation-and-treatment
#1
Farina Hanif, Kanza Muzaffar, Kahkashan Perveen, Saima M Malhi, Shabana U Simjee
Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system tumors. Despite advances in treatment modalities it remains largely incurable. The objective of our review is to provide a holistic picture of GBM epidemiology, etiology, pathogenesis, clinical findings and treatment. A literature search was conducted for GBM at PubMed and Google Scholar, with relevant key words like glioblastoma multiforme, pathogenesis, signs and symptoms, treatment etc., and papers published until 2015 were reviewed...
1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28239502/immunooncology-can-the-right-chimeric-antigen-receptors-t-cell-design-be-made-to-cure-all-types-of-cancers-and-will-it-be-covered
#2
REVIEW
Regina Au
Immunooncology (IO) is the buzz word today and it has everyone doing IO research. If we look back at the history of cancer treatment, the survival rate was measured in months which, according to oncologists, was a lot back then because the mortality rate in most cancers was 100%. However, most traditional chemotherapies were not well tolerated because they would kill both cancerous and healthy cells, which lead to major side effects such as loss of hair, nausea and vomiting, and risk of infection. Survival was better but not much better depending on the type of cancer and the patient's own genetic and physiological make-up...
2017: Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28239214/mental-imagery-based-training-to-modify-mood-and-cognitive-bias-in-adolescents-effects-of-valence-and-perspective
#3
S Burnett Heyes, A Pictet, H Mitchell, S M Raeder, J Y F Lau, E A Holmes, S E Blackwell
Mental imagery has a powerful impact on emotion and cognitive processing in adults, and is implicated in emotional disorders. Research suggests the perspective adopted in mental imagery modulates its emotional impact. However, little is known about the impact of mental imagery in adolescence, despite adolescence being the key time for the onset of emotional dysfunction. We administered computerised positive versus mixed valence picture-word mental imagery training to male adolescent participants (N = 60, aged 11-16 years) across separate field and observer perspective sessions...
2017: Cognitive Therapy and Research
https://www.readbyqxmd.com/read/28239208/exploring-the-dimensionality-of-morphological-knowledge-for-adolescent-readers
#4
Amanda P Goodwin, Yaacov Petscher, Joanne F Carlisle, Alison M Mitchell
This study examined the dimensionality of morphological knowledge. The performance of 371 seventh- and eighth-graders on seven morphological knowledge tasks was investigated using confirmatory factor analysis. Results suggested that morphological knowledge was best fit by a bifactor model with a general factor of morphological knowledge and seven specific factors, representing tasks that tap different facets of morphological knowledge. Next, structural equation modelling was used to explore links to literacy outcomes...
February 2017: Journal of Research in Reading
https://www.readbyqxmd.com/read/28236780/treating-conduct-disorder-an-effectiveness-and-natural-language-analysis-study-of-a-new-family-centred-intervention-program
#5
Kimberly A Stevens, Prof Kevin Ronan, Gene Davies
This paper reports on a new family-centred, feedback-informed intervention focused on evaluating therapeutic outcomes and language changes across treatment for conduct disorder (CD). The study included 26 youth and families from a larger randomised, controlled trial (Ronan et al., in preparation). Outcome measures reflected family functioning/youth compliance, delinquency, and family goal attainment. First- and last-treatment session audio files were transcribed into more than 286,000 words and evaluated through the Linguistic Inquiry and Word Count Analysis program (Pennebaker et al...
November 27, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28236762/relational-vs-attributive-interpretation-of-nominal-compounds-differentially-engages-angular-gyrus-and-anterior-temporal-lobe
#6
Christine Boylan, John C Trueswell, Sharon L Thompson-Schill
The angular gyrus (AG) and anterior temporal lobe (ATL) have been found to respond to a number of tasks involving combinatorial processing. In this study, we investigate the conceptual combination of nominal compounds, and ask whether ATL/AG activity is modulated by the type of combinatorial operation applied to a nominal compound. We compare relational and attributive interpretations of nominal compounds and find that ATL and AG both discriminate these two types, but in distinct ways. While right AG demonstrated greater positive task-responsive activity for relational compounds, there was a greater negative deflection in the BOLD response in left AG for relational compounds...
February 22, 2017: Brain and Language
https://www.readbyqxmd.com/read/28229064/abnormal-auditory-brainstem-response-abr-findings-in-a-near-normal-hearing-child-with-noonan-syndrome
#7
Bahram Jalaei, Mohd Normani Zakaria, Dinsuhaimi Sidek
INTRODUCTION: Noonan syndrome (NS) is a heterogeneous genetic disease that affects many parts of the body. It was named after Dr. Jacqueline Anne Noonan, a paediatric cardiologist. CASE REPORT: We report audiological tests and auditory brainstem response (ABR) findings in a 5-year old Malay boy with NS. Despite showing the marked signs of NS, the child could only produce a few meaningful words. Audiological tests found him to have bilateral mild conductive hearing loss at low frequencies...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28225381/information-seeking-behavior-and-information-needs-in-patients-with-amyotrophic-lateral-sclerosis-analyzing-an-online-patient-community
#8
Juyeon Oh, Jung A Kim
A few studies have examined the specific informational needs of the population with amyotrophic lateral sclerosis. The aims of this study were to describe the information-seeking behavior and information needs of patients with amyotrophic lateral sclerosis and their families in Korea by analyzing messages from an online patient community. A total of 1047 messages from the question and answer forum of the "Lou Gehrig's Disease Network" (http://cafe.daum.net/alsfree) from January 2010 to September 2015 were collected...
February 22, 2017: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/28225287/-predatory-journals-how-their-publishers-operate-and-how-to-avoid-them
#9
Jiří Kratochvíl, Lukáš Plch
Authors who publish in scientific or scholarly journals today face the risk of publishing in so-called predatory journals. These journals exploit the noble idea of the Open Access movement, whose goal is to make the latest scientific findings available for free. Predatory journals, unlike the reputable ones working on an Open Access basis, neglect the review process and publish low-quality submissions. The basic attributes of predatory journals are a very quick review process or even none at all, failure to be transparent about author fees for publishing an article, misleading potential authors by imitating the names of well-established journals, and false information on indexing in renowned databases or assigned impact factor...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28224689/acquisition-of-abstract-concepts-is-influenced-by-emotional-valence
#10
Marta Ponari, Courtenay Frazier Norbury, Gabriella Vigliocco
There is considerable lack of evidence concerning the linguistic and cognitive skills underpinning abstract vocabulary acquisition. The present study considers the role of emotional valence in providing an embodied learning experience in which to anchor abstract meanings. First, analyses of adult ratings of age-of-acquisition, concreteness and valence demonstrate that abstract words acquired early tend to be emotionally valenced. Second, auditory Lexical Decision accuracies of children aged 6-7, 8-9, and 10-11 years (n = 20 per group) complement these analyses, demonstrating that emotional valence facilitates processing of abstract words, but not concrete...
February 21, 2017: Developmental Science
https://www.readbyqxmd.com/read/28224687/children-remember-words-from-ignorant-speakers-but-do-not-attach-meaning-evidence-from-event-related-potentials
#11
Haykaz Mangardich, Mark A Sabbagh
Although we know much about the conditions under which children demonstrate selective social learning, we have a limited understanding of the cognitive mechanisms by which children's selectivity manifests. Here, we report findings from a brain electrophysiological (ERP) study designed to determine the extent to which words presented by ignorant speakers were later both familiar to children and associated with semantic meaning. Forty-eight children (mean age = 6.5 years) first experienced novel word training from either a knowledgeable or an ignorant speaker...
February 21, 2017: Developmental Science
https://www.readbyqxmd.com/read/28223951/speechreading-in-deaf-adults-with-cochlear-implants-evidence-for-perceptual-compensation
#12
Hannah Pimperton, Amelia Ralph-Lewis, Mairéad MacSweeney
Previous research has provided evidence for a speechreading advantage in congenitally deaf adults compared to hearing adults. A 'perceptual compensation' account of this finding proposes that prolonged early onset deafness leads to a greater reliance on visual, as opposed to auditory, information when perceiving speech which in turn results in superior visual speech perception skills in deaf adults. In the current study we tested whether previous demonstrations of a speechreading advantage for profoundly congenitally deaf adults with hearing aids, or no amplificiation, were also apparent in adults with the same deafness profile but who have experienced greater access to the auditory elements of speech via a cochlear implant (CI)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28222910/agents-of-the-father-s-law-in-a-society-of-brothers-a-philosophic-and-psychoanalytic-perspective-on-legitimate-use-of-violence
#13
Efrat Even-Tzur, Uri Hadar
This paper explores subjective processes of "Agents of Law" - individuals who the state grants the authority to use violence - and the dissonance stemming from the contradictory demands posed on them as legitimate users of violence despite the societal taboo against violence. A conceptual model will be offered based on two theoretical legs, Lacanian psychoanalysis and political theories of legitimacy. Specifically, psychoanalytic ideas would serve to examine unconscious processes, subject position and various identifications related to the question of "self-legitimacy" of Agents of Law...
February 17, 2017: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/28222790/the-bear-in-eurasian-plant-names-motivations-and-models
#14
REVIEW
Valeria Kolosova, Ingvar Svanberg, Raivo Kalle, Lisa Strecker, Ayşe Mine Gençler Özkan, Andrea Pieroni, Kevin Cianfaglione, Zsolt Molnár, Nora Papp, Łukasz Łuczaj, Dessislava Dimitrova, Daiva Šeškauskaitė, Jonathan Roper, Avni Hajdari, Renata Sõukand
Ethnolinguistic studies are important for understanding an ethnic group's ideas on the world, expressed in its language. Comparing corresponding aspects of such knowledge might help clarify problems of origin for certain concepts and words, e.g. whether they form common heritage, have an independent origin, are borrowings, or calques. The current study was conducted on the material in Slavonic, Baltic, Germanic, Romance, Finno-Ugrian, Turkic and Albanian languages. The bear was chosen as being a large, dangerous animal, important in traditional culture, whose name is widely reflected in folk plant names...
February 21, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28221087/fechner-s-law-in-metacognition-a-quantitative-model-of-visual-working-memory-confidence
#15
Ronald van den Berg, Aspen H Yoo, Wei Ji Ma
Although visual working memory (VWM) has been studied extensively, it is unknown how people form confidence judgments about their memories. Peirce (1878) speculated that Fechner's law-which states that sensation is proportional to the logarithm of stimulus intensity-might apply to confidence reports. Based on this idea, we hypothesize that humans map the precision of their VWM contents to a confidence rating through Fechner's law. We incorporate this hypothesis into the best available model of VWM encoding and fit it to data from a delayed-estimation experiment...
March 2017: Psychological Review
https://www.readbyqxmd.com/read/28219958/interpretation-and-use-of-evidence-in-state-policymaking-a-qualitative-analysis
#16
Dorie E Apollonio, Lisa A Bero
INTRODUCTION: Researchers advocating for evidence-informed policy have attempted to encourage policymakers to develop a greater understanding of research and researchers to develop a better understanding of the policymaking process. Our aim was to apply findings drawn from studies of the policymaking process, specifically the theory of policy windows, to identify strategies used to integrate evidence into policymaking and points in the policymaking process where evidence was more or less relevant...
February 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28219259/the-role-of-cognitive-load-in-intentional-forgetting-using-the-think-no-think-task
#17
Saima Noreen, Jan W de Fockert
We investigated the role of cognitive control in intentional forgetting by manipulating working memory load during the think/no-think task. In two experiments, participants learned a series of cue-target word pairs and were asked to recall the target words associated with some cues or to avoid thinking about the target associated with other cues. In addition to this, participants also performed a modified version of the n-back task which required them to respond to the identity of a single target letter present in the currently presented cue word (n = 0 condition, low working memory load), and in either the previous cue word (n = 1 condition, high working memory load, Experiment 1) or the cue word presented two trials previously (n = 2 condition, high working memory load, Experiment 2)...
January 2017: Experimental Psychology
https://www.readbyqxmd.com/read/28218161/directly-observed-iron-supplementation-for-control-of-iron-deficiency-anemia
#18
REVIEW
Mohan Bairwa, Farhad Ahamed, Smita Sinha, Kapil Yadav, Shashi Kant, Chandrakant S Pandav
Anemia is major public health problem affecting 1.6 billion people worldwide. The poor compliance of iron supplementation remains main contributor for high prevalence of anemia. The current paper reviewed the effectiveness of direct observation of oral iron supplementation on anemia. A systematic search was performed through electronic databases and local libraries. Search strategies used subject headings and key words "directly observed" and "iron supplementation." Searches were sought through April 2014. A total of 14 articles were included in the study...
January 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28216857/body-image-and-sexuality-in-women-survivors-of-breast-cancer-in-india-qualitative-findings
#19
Michelle S Barthakur, Mahendra P Sharma, Santosh K Chaturvedi, Suraj K Manjunath
OBJECTIVES: With increasing rates of breast cancer survivors, psychosocial issues surrounding cancer survivorship have been gaining prominence. The following article reports on body image and sexuality-related issues in aftermath of the diagnosis and its treatment in the Indian context. MATERIALS AND METHODS: Research design was mixed method, cross-sectional, and exploratory in nature. Quantitative sample consisted of fifty survivors while the qualitative sample size included 15 out of the 50 total breast cancer survivors who were recruited from hospitals, nongovernmental organization, and through word-of-mouth...
January 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28215877/my-friends-have-a-word-for-it-event-related-potentials-evidence-of-how-social-risk-inhibits-purchase-intention
#20
Qian Shang, Guanxiong Pei, Jia Jin
Social risk refers to the potential disapproval from significant others (especially family or friends), and it is crucial in dissuading consumers from making decisions to purchase. The current study explored the neural process underlying how social risk influenced people's purchase intention. Event-related potentials (ERPs) were employed to investigate the electrophysiological process when subjects evaluated their purchase intention for products with social risk factors. The behavioral data showed that the social risk condition inhibited people's purchase intention compared to the control condition...
February 12, 2017: Neuroscience Letters
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