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Apraxia of speech

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https://www.readbyqxmd.com/read/27882295/neuroanatomical-correlates-of-childhood-apraxia-of-speech-a-connectomic-approach
#1
Simona Fiori, Andrea Guzzetta, Jhimli Mitra, Kerstin Pannek, Rosa Pasquariello, Paola Cipriani, Michela Tosetti, Giovanni Cioni, Stephen E Rose, Anna Chilosi
Childhood apraxia of speech (CAS) is a paediatric speech sound disorder in which precision and consistency of speech movements are impaired. Most children with idiopathic CAS have normal structural brain MRI. We hypothesize that children with CAS have altered structural connectivity in speech/language networks compared to controls and that these altered connections are related to functional speech/language measures. Whole brain probabilistic tractography, using constrained spherical deconvolution, was performed for connectome generation in 17 children with CAS and 10 age-matched controls...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27812326/a-foxp2-mutation-implicated-in-human-speech-deficits-alters-sequencing-of-ultrasonic-vocalizations-in-adult-male-mice
#2
Jonathan Chabout, Abhra Sarkar, Sheel R Patel, Taylor Radden, David B Dunson, Simon E Fisher, Erich D Jarvis
Development of proficient spoken language skills is disrupted by mutations of the FOXP2 transcription factor. A heterozygous missense mutation in the KE family causes speech apraxia, involving difficulty producing words with complex learned sequences of syllables. Manipulations in songbirds have helped to elucidate the role of this gene in vocal learning, but findings in non-human mammals have been limited or inconclusive. Here, we performed a systematic study of ultrasonic vocalizations (USVs) of adult male mice carrying the KE family mutation...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27790241/improved-necker-cube-drawing-based-assessment-battery-for-constructional-apraxia-the-mie-constructional-apraxia-scale-mcas
#3
Masayuki Satoh, Chika Mori, Kana Matsuda, Yukito Ueda, Ken-Ichi Tabei, Hirotaka Kida, Hidekazu Tomimoto
BACKGROUND/AIMS: Constructional apraxia (CA) is usually diagnosed by having patients draw figures; however, the reported assessments only evaluate the drawn figure. We designed a new assessment battery for CA (the Mie Constructional Apraxia Scale, MCAS) which includes both the shape and drawing process, and investigated its utility against other assessment methods. METHODS: We designed the MCAS, and evaluated inter- and intrarater reliability. We also investigated the sensitivity, specificity, and positive and negative predictive values in dementia patients, and compared MCAS assessment with other reported batteries in the same subjects...
September 2016: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/27790240/lack-of-frank-agrammatism-in-the-nonfluent-agrammatic-variant-of-primary-progressive-aphasia
#4
Naida L Graham, Carol Leonard, David F Tang-Wai, Sandra Black, Tiffany W Chow, Chris J M Scott, Alicia A McNeely, Mario Masellis, Elizabeth Rochon
BACKGROUND/AIMS: Frank agrammatism, defined as the omission and/or substitution of grammatical morphemes with associated grammatical errors, is variably reported in patients with nonfluent variant primary progressive aphasia (nfPPA). This study addressed whether frank agrammatism is typical in agrammatic nfPPA patients when this feature is not required for diagnosis. METHOD: We assessed grammatical production in 9 patients who satisfied current diagnostic criteria...
September 2016: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/27771043/tracking-the-development-of-agrammatic-aphasia-a-tensor-based-morphometry-study
#5
Jennifer L Whitwell, Joseph R Duffy, Mary M Machulda, Heather M Clark, Edythe A Strand, Matthew L Senjem, Jeffrey L Gunter, Anthony J Spychalla, Ronald C Petersen, Clifford R Jack, Keith A Josephs
Agrammatic aphasia can be observed in neurodegenerative disorders and has been traditionally linked with damage to Broca's area, although there have been disagreements concerning whether damage to Broca's area is necessary or sufficient for the development of agrammatism. We aimed to investigate the neuroanatomical correlates of the emergence of agrammatic aphasia utilizing a unique cohort of patients with primary progressive apraxia of speech (PPAOS) that did not have agrammatism at baseline but developed agrammatic aphasia over time...
September 30, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/27750297/articulatory-control-in-childhood-apraxia-of-speech-in-a-novel-word-learning-task
#6
Julie Case, Maria I Grigos
Purpose: Articulatory control and speech production accuracy were examined in children with childhood apraxia of speech (CAS) and typically developing (TD) controls within a novel word-learning task to better understand the influence of planning and programming deficits in the production of unfamiliar words. Method: Participants included 16 children between the ages of 5 and 6 years (8 CAS, 8 TD). Short- and long-term changes in lip and jaw movement, consonant and vowel accuracy, and token-to-token consistency were measured for 2 novel words that differed in articulatory complexity...
October 17, 2016: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/27707700/cognitive-linguistic-and-motor-abilities-in-a-multigenerational-family-with-childhood-apraxia-of-speech
#7
Bronwyn Carrigg, Louise Parry, Elise Baker, Lawrence D Shriberg, Kirrie J Ballard
OBJECTIVE: This study describes the phenotype in a large family with a strong, multigenerational history of severe speech sound disorder (SSD) persisting into adolescence and adulthood in approximately half the cases. Aims were to determine whether a core phenotype, broader than speech, separated persistent from resolved SSD cases; and to ascertain the uniqueness of the phenotype relative to published cases. METHOD: Eleven members of the PM family (9-55 years) were assessed across cognitive, language, literacy, speech, phonological processing, numeracy, and motor domains...
October 5, 2016: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/27625603/intensive-treatment-with-ultrasound-visual-feedback-for-speech-sound-errors-in-childhood-apraxia
#8
Jonathan L Preston, Megan C Leece, Edwin Maas
Ultrasound imaging is an adjunct to traditional speech therapy that has shown to be beneficial in the remediation of speech sound errors. Ultrasound biofeedback can be utilized during therapy to provide clients with additional knowledge about their tongue shapes when attempting to produce sounds that are erroneous. The additional feedback may assist children with childhood apraxia of speech (CAS) in stabilizing motor patterns, thereby facilitating more consistent and accurate productions of sounds and syllables...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27591108/post-stroke-pure-apraxia-of-speech-a-rare-experience
#9
Katarzyna Ewa Polanowska, Iwona Pietrzyk-Krawczyk
Apraxia of speech (AOS) is a motor speech disorder, most typically caused by stroke, which in its "pure" form (without other speech-language deficits) is very rare in clinical practice. Because some observable characteristics of AOS overlap with more common verbal communication neurologic syndromes (i.e. aphasia, dysarthria) distinguishing them may be difficult. The present study describes AOS in a 49-year-old right-handed male after left-hemispheric stroke. Analysis of his articulatory and prosodic abnormalities in the context of intact communicative abilities as well as description of symptoms dynamics over time provides valuable information for clinical diagnosis of this specific disorder and prognosis for its recovery...
August 23, 2016: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/27555813/mild-developmental-foreign-accent-syndrome-and-psychiatric-comorbidity-altered-white-matter-integrity-in-speech-and-emotion-regulation-networks
#10
Marcelo L Berthier, Núria Roé-Vellvé, Ignacio Moreno-Torres, Carles Falcon, Karl Thurnhofer-Hemsi, José Paredes-Pacheco, María J Torres-Prioris, Irene De-Torres, Francisco Alfaro, Antonio L Gutiérrez-Cardo, Miquel Baquero, Rafael Ruiz-Cruces, Guadalupe Dávila
Foreign accent syndrome (FAS) is a speech disorder that is defined by the emergence of a peculiar manner of articulation and intonation which is perceived as foreign. In most cases of acquired FAS (AFAS) the new accent is secondary to small focal lesions involving components of the bilaterally distributed neural network for speech production. In the past few years FAS has also been described in different psychiatric conditions (conversion disorder, bipolar disorder, and schizophrenia) as well as in developmental disorders (specific language impairment, apraxia of speech)...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27553583/visual-signs-and-symptoms-of-corticobasal-degeneration
#11
REVIEW
Richard A Armstrong
Corticobasal degeneration is a rare, progressive neurodegenerative disease and a member of the 'parkinsonian' group of disorders, which also includes Parkinson's disease, progressive supranuclear palsy, dementia with Lewy bodies and multiple system atrophy. The most common initial symptom is limb clumsiness, usually affecting one side of the body, with or without accompanying rigidity or tremor. Subsequently, the disease affects gait and there is a slow progression to influence ipsilateral arms and legs. Apraxia and dementia are the most common cortical signs...
November 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27538892/aphasia-rehabilitation-during-adolescence-a-case-report
#12
Jacqueline Laures-Gore, Tiffany McCusker, Leila L Hartley
PURPOSE: Descriptions of speech-language interventions addressing the unique aspects of aphasia in adolescence appear to be nonexistent. The current paper presents the case of a male adolescent who experienced a stroke with resultant aphasia and the speech and language therapy he received. Furthermore, we discuss the issues that are unique to an adolescent with aphasia and how they were addressed with this particular patient. METHODS: Traditional language and apraxia therapy was provided to this patient with inclusion of technology and academic topics...
August 18, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27524196/-profiles-of-cognitive-and-language-impairment-of-logopenic-and-non-fluent-variant-of-primary-progressive-aphasia
#13
D Li, L N Zhao, H M Jin, M Zhang, D M Guo, Y Y Yu, L Y Wu, Y Tang, F Y Li, A H Zhou, Y Han, J P Jia
OBJECTIVE: To decipher the cognitive and linguistic feature of logopenic variant primary progressive aphasia (lv-PPA) and nonfluent variant primary progressive aphasia (nfv-PPA) and to explore the extent to which cognitive and language impairment contribute to the dysfunction of activity of daily living(ADL). METHODS: Seven lv-PPA and five nfv-PPA were enrolled in memory clinic of Xuanwu Hospital, Capital Medical University from January 2015 to January 2016 accordig to the international consensus criteria for PPA and its three subtypes...
August 2, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27492818/bridging-the-gap-between-speech-and-language-using-multimodal-treatment-in-a-child-with-apraxia
#14
Cheryl D Tierney, Kathleen Pitterle, Marie Kurtz, Mark Nakhla, Carlyn Todorow
Childhood apraxia of speech is a neurologic speech sound disorder in which children have difficulty constructing words and sounds due to poor motor planning and coordination of the articulators required for speech sound production. We report the case of a 3-year-old boy strongly suspected to have childhood apraxia of speech at 18 months of age who used multimodal communication to facilitate language development throughout his work with a speech language pathologist. In 18 months of an intensive structured program, he exhibited atypical rapid improvement, progressing from having no intelligible speech to achieving age-appropriate articulation...
September 2016: Pediatrics
https://www.readbyqxmd.com/read/27264534/brain-damage-associated-with-apraxia-of-speech-evidence-from-case-studies
#15
Dana Moser, Alexandra Basilakos, Paul Fillmore, Julius Fridriksson
The site of crucial damage that causes acquired apraxia of speech (AOS) has been debated in the literature. This study presents five in-depth cases that offer insight into the role of brain areas involved in AOS. Four of the examined participants had a primary impairment of AOS either with (n = 2) or without concomitant mild aphasia (n = 2). The fifth participant presented with a lesion relatively isolated to the left anterior insula (AIns-L), damage that is rarely reported in the literature, but without AOS...
August 2016: Neurocase
https://www.readbyqxmd.com/read/27258125/structural-and-functional-integration-between-dorsal-and-ventral-language-streams-as-revealed-by-blunt-dissection-and-direct-electrical-stimulation
#16
Silvio Sarubbo, Alessandro De Benedictis, Stefano Merler, Emmanuel Mandonnet, Mattia Barbareschi, Monica Dallabona, Franco Chioffi, Hugues Duffau
The most accepted framework of language processing includes a dorsal phonological and a ventral semantic pathway, connecting a wide network of distributed cortical hubs. However, the cortico-subcortical connectivity and the reciprocal anatomical relationships of this dual-stream system are not completely clarified. We performed an original blunt microdissection of 10 hemispheres with the exposition of locoregional short fibers and six long-range fascicles involved in language elaboration. Special attention was addressed to the analysis of termination sites and anatomical relationships between long- and short-range fascicles...
June 3, 2016: Human Brain Mapping
https://www.readbyqxmd.com/read/27251676/utility-of-testing-for-apraxia-and-associated-features-in-dementia
#17
Samrah Ahmed, Ian Baker, Sian Thompson, Masud Husain, Christopher R Butler
INTRODUCTION: Existing literature suggests that the presence or absence of apraxia and associated parietal deficits may be clinically relevant in differential diagnosis of dementia syndromes. AIM: This study investigated the profile of these features in Alzheimer's disease (AD) and frontotemporal dementia (FTD) spectrum disorders, at first presentation. METHODS: Retrospective case note analysis was undertaken in 111 patients who presented to the Oxford Cognitive Disorders Clinic, Oxford, UK, including 29 amnestic AD, 12 posterior cortical atrophy (PCA), 12 logopenic primary progressive aphasia (lvPPA), 20 behavioural variant FTD (bvFTD), 7 non-fluent variant PPA (nfvPPA), 6 semantic variant PPA (svPPA) and 25 patients with subjective cognitive impairment (SCI)...
November 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27241138/childhood-apraxia-of-speech-a-survey-of-praxis-and-typical-speech-characteristics
#18
Ann Malmenholt, Anette Lohmander, Anita McAllister
PURPOSE: The purpose of this study was to investigate current knowledge of the diagnosis childhood apraxia of speech (CAS) in Sweden and compare speech characteristics and symptoms to those of earlier survey findings in mainly English-speakers. METHOD: In a web-based questionnaire 178 Swedish speech-language pathologists (SLPs) anonymously answered questions about their perception of typical speech characteristics for CAS. They graded own assessment skills and estimated clinical occurrence...
May 31, 2016: Logopedics, Phoniatrics, Vocology
https://www.readbyqxmd.com/read/27166164/progressive-apraxia-of-speech-in-a-patient-with-a-c9orf72-mutation
#19
Francesca Di Stefano, Monica Melis, Antonino Cannas, Giuseppe Borghero, Maria R Murru, Daniela Corongiu, Stefania Cuccu, Stefania Tranquilli, Maria G Marrosu, Francesco Marrosu, Gianluca Floris
No abstract text is available yet for this article.
May 11, 2016: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/27161038/telehealth-delivery-of-rapid-syllable-transitions-rest-treatment-for-childhood-apraxia-of-speech
#20
Donna C Thomas, Patricia McCabe, Kirrie J Ballard, Michelle Lincoln
BACKGROUND: Rapid Syllable Transitions (ReST) treatment uses pseudo-word targets with varying lexical stress to target simultaneously articulation, prosodic accuracy and coarticulatory transitions in childhood apraxia of speech (CAS). The treatment is efficacious for the acquisition of imitated pseudo-words, and generalization of skill to untreated pseudo-words and real words. Despite the growing popularity of telehealth as a method of service delivery, there is no research into the efficacy of telehealth treatments for CAS...
May 10, 2016: International Journal of Language & Communication Disorders
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