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Ester Bonmati, Yipeng Hu, Eli Gibson, Laura Uribarri, Geri Keane, Kurinchi Gurusami, Brian Davidson, Stephen P Pereira, Matthew J Clarkson, Dean C Barratt
PURPOSE: Navigation of endoscopic ultrasound (EUS)-guided procedures of the upper gastrointestinal (GI) system can be technically challenging due to the small fields-of-view of ultrasound and optical devices, as well as the anatomical variability and limited number of orienting landmarks during navigation. Co-registration of an EUS device and a pre-procedure 3D image can enhance the ability to navigate. However, the fidelity of this contextual information depends on the accuracy of registration...
April 16, 2018: International Journal of Computer Assisted Radiology and Surgery
Antoine Néel, Anaïs Wahbi, Benoit Tessoulin, Julien Boileau, Dorothée Carpentier, Olivier Decaux, Laurence Fardet, Guillaume Geri, Pascal Godmer, Cécile Goujard, Hervé Maisonneuve, Arnaud Mari, Jacques Pouchot, Jean-Marc Ziza, Cédric Bretonnière, Mohamed Hamidou
BACKGROUND: Adult-onset Still disease (AOSD) is a rare systemic inflammatory disorder. A few patients develop organ complications that can be life-threatening. Our objectives were to describe the disease course and phenotype of life-threatening AOSD, including response to therapy and long-term outcome. METHODS: A multicenter case series of intensive care medicine (ICU) patients with life-threatening AOSD and a systematic literature review. RESULTS: Twenty patients were included...
April 11, 2018: Critical Care: the Official Journal of the Critical Care Forum
Omri Gillath, Gery Karantzas
Attachment security priming has been used to shed light on the cognitive processes related to attachment internal working models as well as the cognitive substrates of people's attachment-related affect and behavior. Security primes activate a sense of attachment security by making mental representations in one's memory more accessible and salient. In the current paper, we report on a qualitative synthesis of 20 studies published in the last two years to determine the effects of security priming. We found that supraliminally administered security priming (especially via guided imagery or visualization) is associated with beneficial effects across a diverse set of domains...
March 15, 2018: Current Opinion in Psychology
Nabiha Faisal, Marc Bilodeau, Bandar Aljudaibi, Geri Hirch, Eric M Yoshida, Trana Hussaini, Maged P Ghali, Stephen E Congly, Mang M Ma, Leslie B Lilly
OBJECTIVES: We assessed the impact of sofosbuvir-based regimens on renal function in liver transplant recipients with recurrent hepatitis C virus and the role of renal function on the efficacy and safety of these regimens. MATERIALS AND METHODS: In an expanded pan-Canadian cohort, 180 liver transplant recipients were treated with sofosbuvir-based regimens for hepatitis C virus recurrence from January 2014 to May 2015. Mean age was 58 ± 6.85 years, and 50% had F3/4 fibrosis...
April 4, 2018: Experimental and Clinical Transplantation
A M P B Seneviratne, Geri Kreitzer
No abstract text is available yet for this article.
March 30, 2018: Aging
Tzeyu L Michaud, Mohammad Siahpush, Robert J Schwab, Leslie A Eiland, Mary DeVany, Geri Hansen, Tammy S Slachetka, Eugene Boilesen, Hyo Jung Tak, Fernando A Wilson, Hongmei Wang, José A Pagán, Dejun Su
The objective of this study was to evaluate changes in clinical outcomes for patients with type 2 diabetes (T2D) after a 3-month remote patient monitoring (RPM) program, and examine the relationship between hemoglobin A1c (HbA1c) outcomes and participant characteristics. The study sample included 955 patients with T2D who were admitted to an urban Midwestern medical center for any reason from 2014 to 2017, and used RPM for 3 months after discharge. Clinical outcomes included HbA1c, weight, body mass index (BMI), and patient activation scores...
March 27, 2018: Population Health Management
Erika M Manczak, Geri R Donenberg, Erin Emerson
The current study sought to test whether higher quality mother-daughter communication would buffer associations between maternal depressive symptoms and girls' internalizing and externalizing psychopathology symptoms among urban African American girls across a 12-month period. One hundred ninety-four treatment-seeking urban African American adolescent girls, ages 12-16, and their mothers participated in the study. Every 6 months (for up to 3 assessments), daughters reported on their internalizing and externalizing symptoms, mothers reported on their depressive symptoms, and both mothers and daughters reported on the quality of their dyadic communication...
March 26, 2018: Journal of Clinical Child and Adolescent Psychology
Xu Shan Sun, Cécile Michel, Emmanuel Babin, Dominique De Raucourt, Adeline Péchery, Elisabeta Gherga, Bernard Géry, Carmen Florescu, Jean Bourhis, Juliette Thariat
Median survival for recurrent/metastatic head and neck squamous cell cancer (HNSCC) patients is about 10 months after first-line best systemic treatment. We aimed to assess current approaches of oligometastatic HNSCC patients by the analysis of current concept and published data (1995-2017) in this population. Five-year survival rates are over 20% in selected patients who undergo metastasis-directed therapy by either surgery or stereotactic irradiation. Human papillomavirus(+) HNSCC patients have more disseminated metastases but respond more favorably and also benefit from ablative treatments...
March 26, 2018: Future Oncology
Victor Waldmann, Wulfran Bougouin, Nicole Karam, Florence Dumas, Ardalan Sharifzadehgan, Estelle Gandjbakhch, Vincent Algalarrondo, Kumar Narayanan, Alexandre Zhao, Denis Amet, Daniel Jost, Guillaume Geri, Lionel Lamhaut, Frankie Beganton, Bertrand Ludes, Patrick Bruneval, Isabelle Plu, Françoise Hidden-Lucet, Juliette Albuisson, Thomas Lavergne, Olivier Piot, Christine Alonso, Antoine Leenhardt, Nicolas Lellouche, Fabrice Extramiana, Alain Cariou, Xavier Jouven, Eloi Marijon
Aims: Recent studies have shown that in more than half of apparently unexplained sudden cardiac arrests (SCA), a specific aetiology can be unmasked by a careful evaluation. The characteristics and the extent to which such cases undergo a systematic thorough investigation in real-life practice are unknown. Methods and results: Data were analysed from an ongoing study, collecting all cases of out-of-hospital cardiac arrest in Paris area. Investigations performed during the index hospitalization or planned after discharge were gathered to evaluate the completeness of assessment of unexplained SCA...
March 16, 2018: European Heart Journal
Marine Paul, Wulfran Bougouin, Florence Dumas, Guillaume Geri, Benoit Champigneulle, Lucie Guillemet, Omar Ben Hadj Salem, Stéphane Legriel, Jean-Daniel Chiche, Julien Charpentier, Jean-Paul Mira, Claudio Sandroni, Alain Cariou
PURPOSE: Although guidelines on post-resuscitation care recommend the use of short-acting agents for sedation during targeted temperature management (TTM) after cardiac arrest (CA), the potential advantages of this strategy have not been clinically demonstrated. METHODS: We compared two sedation regimens (propofol-remifentanil, period P2, vs midazolam-fentanyl, period P1) among comatose TTM-treated CA survivors. Management protocol, apart from sedation and neuromuscular blockers use, did not change between the two periods...
March 16, 2018: Resuscitation
Dawn M Holman, Helen Ding, Gery P Guy, Meg Watson, Anne M Hartman, Frank M Perna
Importance: Monitoring sun protection and sunburn over time at the population level can provide valuable information about progress toward skin cancer prevention goals and inform future intervention efforts. Objective: To examine the prevalence of sun protection use (shade, sunscreen, and clothing) and sunburn and the association between sunburn and individual characteristics and health behaviors in the US population. Design, Setting, and Participants: In this cross-sectional study using a nationally representative sample of 31 162 US adults from the 2015 National Health Interview Survey-Cancer Control Supplement, household interviews of civilian, noninstitutionalized US adults were conducted throughout 2015 in person and completed on the telephone when necessary...
March 14, 2018: JAMA Dermatology
Richard J Wood, Carlos A Reck-Burneo, Daniel Dajusta, Christina Ching, Rama Jayanthi, D Gregory Bates, Molly E Fuchs, Katherine McCracken, Geri Hewitt, Marc A Levitt
No abstract text is available yet for this article.
March 2018: Journal of Pediatric Surgery
Gery C Karantzas, Daniel Romano, Juwon Lee
Attachment theory is an important framework from which to examine familial aged care. Despite this, the role of attachment in later-life caregiving remains unclear. The current study presents a systematic review of papers within the last five years on attachment and various outcomes related to familial aged care. For the caregiver, attachment anxiety was associated with poorer mental health, and attachment insecurity with a more controlling manner of caregiving. The few studies conducted with care recipients found that attachment insecurity was associated with greater self-appraisals of dementia symptoms and a lower sense of security...
March 6, 2018: Current Opinion in Psychology
Christopher W Baugh, Carol L Clark, Jason W Wilson, Ian G Stiell, Abraham G Kocheril, Krista K Luck, Troy D Myers, Charles V Pollack, Steven K Roumpf, Gery F Tomassoni, James M Williams, Brian B Patel, Fred Wu, Jesse M Pines
Atrial fibrillation and flutter (AF) is a common condition among emergency department (ED) patients in the United States (US). Traditionally, ED care for primary complaints related to AF focus on rate control, and patients are often admitted to an inpatient setting for further care. Inpatient care may include further telemetry monitoring and diagnostic testing, rhythm control, a search for identification of AF etiology, and stroke prophylaxis. However, many patients are eligible for safe and effective outpatient management pathways...
March 10, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Omri Gillath, Gery C Karantzas, Juwon Lee
The current review covers two lines of research linking attachment and social networks. One focuses on attachment networks (the people who fulfill one's attachment needs), examining composition and age-related differences pertaining to these networks. The other line integrates attachment with social network analysis to investigate how individual differences in adult attachment are associated with the management and characteristics (e.g., density, multiplexity, and centrality) of people's social networks. We show that most people's attachment networks are small and hierarchical, with one figure being the primary attachment figure (often a mother or romantic partner, depending on age)...
February 21, 2018: Current Opinion in Psychology
Jess C Hohenstein, Eric Ps Baumer, Lindsay Reynolds, Elizabeth L Murnane, Dakota O'Dell, Seoho Lee, Shion Guha, Yu Qi, Erin Rieger, Geri Gay
BACKGROUND: Technological advances in personal informatics allow people to track their own health in a variety of ways, representing a dramatic change in individuals' control of their own wellness. However, research regarding patient interpretation of traditional medical tests highlights the risks in making complex medical data available to a general audience. OBJECTIVE: This study aimed to explore how people interpret medical test results, examined in the context of a mobile blood testing system developed to enable self-care and health management...
February 28, 2018: JMIR Human Factors
Antoine Géry, Christelle Dubreule, Véronique André, Jean-Philippe Rioult, Valérie Bouchart, Natacha Heutte, Philippe Eldin de Pécoulas, Tetyana Krivomaz, David Garon
BACKGROUND: Inonotus obliquus, also known as Chaga, is a parasitic fungus growing on birches and used in traditional medicine (especially by Khanty people) to treat various health problems. In this study, we aimed to quantify the 3 metabolites frequently cited in literature, that is, betulin, betulinic acid, and inotodiol in the Chaga recently discovered in forests located in Normandy (France), and to compare their concentrations with Ukrainian and Canadian Chaga. This study also explores the cytotoxicity of the French Chaga against cancer-derived cells and transformed cells...
February 1, 2018: Integrative Cancer Therapies
Faith E Fletcher, Celia Fisher, Meredith K Buchberg, Brenikki Floyd, Anna Hotton, Angelica Ehioba, Geri Donenberg
Despite the demonstrated effectiveness of preexposure prophylaxis (PrEP) to reduce incident HIV infections, PrEP's potential as an HIV prevention strategy for adolescent populations is unknown. This study assessed perceptions of adolescent PrEP use and clinical trial participation among African American women and their adolescent daughters. We conducted focus group discussions with 15 African American mother/daughter pairs ( N = 30). Findings suggest a general lack of PrEP awareness, favorable attitudes toward adolescent PrEP use, altruistic attitudes regarding research participation among daughters, and less favorable attitudes toward adolescent clinical trial participation among mothers...
February 1, 2018: Journal of Empirical Research on Human Research Ethics: JERHRE
L F Mendes, H Katagiri, W L Tam, Y C Chai, L Geris, S J Roberts, F P Luyten
BACKGROUND: Chondrogenic mesenchymal stem cells (MSCs) have not yet been used to address the clinical demands of large osteochondral joint surface defects. In this study, self-assembling tissue intermediates (TIs) derived from human periosteum-derived stem/progenitor cells (hPDCs) were generated and validated for stable cartilage formation in vivo using two different animal models. METHODS: hPDCs were aggregated and cultured in the presence of a novel growth factor (GF) cocktail comprising of transforming growth factor (TGF)-β1, bone morphogenetic protein (BMP)2, growth differentiation factor (GDF)5, BMP6, and fibroblast growth factor (FGF)2...
February 21, 2018: Stem Cell Research & Therapy
Amy J Davidoff, Gery P Guy, Xin Hu, Felisa Gonzales, Xuesong Han, Zhiyuan Zheng, Helen Parsons, Donatus U Ekwueme, Ahmedin Jemal
BACKGROUND: The Affordable Care Act (ACA) improved health care coverage accessibility by expanding Medicaid eligibility, creating insurance Marketplaces, and subsidizing premiums. We examine coverage changes associated with ACA implementation, comparing adults with and without a cancer history. METHODS: We included nonelderly adults from the 2012 to 2015 National Health Interview Survey. Using information on state Medicaid policies (2013), expansion decisions (2015), family structure, income, insurance offers, and current coverage, we assigned adults in all 4 years to mutually exclusive eligibility categories including: Medicaid-eligible pre-ACA; expansion eligible for Medicaid; and Marketplace premium subsidy eligible...
March 2018: Medical Care
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