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https://www.readbyqxmd.com/read/28749619/healthy-plant-foods-intake-could-protect-against-prostate-cancer-risk-a-case-control-study
#1
Yahya Jalilpiran, Erfan Hezaveh, Salmeh Bahmanpour, Shiva Faghih
Background: Several studies have investigated the association between healthy plant foods intake and prostate cancer risk with inconsistent results. So this study was conducted to examine the existence of any possible association between healthy plant foods and prostate cancer risk. Materials and Methods: Sixty newly diagnosed prostate cancer cases and 60 controls engaged in a hospital-based case-control study. A validated 16o-items semi-quantitative FFQ was used to assess usual dietary intakes. Energy-adjusted amounts of healthy plant foods intake were calculated using the residual method...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749616/joint-effects-of-low-body-mass-index-and-alcohol-consumption-on-developing-esophageal-squamous-cell-cancer-a-korean-nationwide-population-based-cohort-study
#2
Yoon Jin Choi, Dong Ho Lee, Kyung Do Han, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim
Objective: In Korea, 95% of esophageal cancer (EC) was the squamous cell-type. We sought to determine the combined risk of alcohol consumption on developing esophageal squamous cell carcinoma (ESCC) in pre-diagnostic underweight subjects using Korean national data. Methods: We analyzed the clinical data from a total of 264,084 individuals aged 40 years or older, who received healthcare checkups arranged by the national insurance program, between 2003 and 2008 in Korea. Cox proportional hazards regression was used after adjusting confounding factors...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749548/c-myc-positive-relapsed-and-refractory-diffuse-large-b-cell-lymphoma-impact-of-additional-hits-and-outcomes-with-subsequent-therapy
#3
Narendranath Epperla, Kami J Maddocks, Mohammed Salhab, Julio C Chavez, Nishitha Reddy, Reem Karmali, Elvira Umyarova, Veronika Bachanova, Cristiana Costa, Martha Glenn, Oscar Calzada, Ana C Xavier, Zheng Zhou, Nasheed M Hossain, Francisco J Hernandez-Ilizaliturri, Zeina Al-Mansour, Stefan K Barta, Saurabh Chhabra, Frederick Lansigan, Amitkumar Mehta, Michael V Jaglal, Andrew Evans, Christopher R Flowers, Jonathon B Cohen, Timothy S Fenske, Mehdi Hamadani, Luciano J Costa
BACKGROUND: The impact of MYC proto-oncogene, basic helix-loop-helix (MYC) translocations (with or without additional rearrangements involving the B-cell lymphoma 2 [BCL2] or BCL6 genes) on the response to salvage therapy and survival in patients with diffuse large B-cell lymphoma (DLBCL) who experience primary treatment failure is not well defined. METHODS: This was a multicenter, retrospective study of the impact of MYC, BCL2, and BCL6 rearrangements in patients with DLBCL who failed to achieve complete remission or relapsed within 6 months after they completed upfront chemoimmunotherapy...
July 27, 2017: Cancer
https://www.readbyqxmd.com/read/28749488/trends-in-provider-initiated-versus-spontaneous-preterm-deliveries-2004-2013
#4
M L Ada, M R Hacker, T H Golen, M J Haviland, S A Shainker, H H Burris
OBJECTIVE: The objectives of this study were as follows: (i) to estimate the proportion of preterm deliveries at a tertiary perinatal center that were provider-initiated versus spontaneous before and after a 2009 policy to reduce elective early-term deliveries, and (ii)to evaluate whether shifts in type of preterm delivery varied by race/ethnicity. METHOD: We performed a retrospective cohort study of preterm deliveries over a 10-year period, 2004 to 2013, including detailed review of 929 of 5566 preterm deliveries, to designate each delivery as provider-initiated or spontaneous...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28749485/thoracic-fluid-content-by-electric-bioimpedance-correlates-with-respiratory-distress-in-newborns
#5
G Paviotti, A De Cunto, V Moressa, C Bettiol, S Demarini
OBJECTIVE: The objective of the study was to compare thoracic fluid content (TFC) between newborn infants with and without respiratory distress. We tested the hypothesis that TFC would be higher in infants with respiratory distress. STUDY DESIGN: A total of 96 newborn infants, gestational age 37.9 (2.6) weeks, were enrolled at birth. TFC by electrical bioimpedance was recorded within 3 h after birth (TFC1) and at 24 h of life (TFC2). RESULTS: TFC1 was higher in infants with respiratory distress at birth (76...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28749483/surgical-site-infections-in-neonates-are-independently-associated-with-longer-hospitalizations
#6
E A Gilje, M J Hossain, C D Vinocur, L Berman
OBJECTIVE: There is limited data characterizing the risk and impact of surgical site infection (SSI) in neonates; this makes it difficult to identify factors that increase neonatal SSI risk and to determine how SSI affects outcomes in this special population. STUDY DESIGN: The American College of Surgeons National Surgical Improvement Program Pediatric (NSQIP-P) collected data on children undergoing surgery at children's hospitals from 2012 to 2014. Neonates undergoing general surgical procedures were characterized with regard to demographic characteristics and comorbidities...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28749482/-the-obesity-paradox-a-reconsideration-of-obesity-and-the-risk-of-preterm-birth
#7
A Tsur, J A Mayo, R J Wong, G M Shaw, D K Stevenson, J B Gould
OBJECTIVE: The association between obesity and spontaneous preterm births (sPTBs) has been shown to be influenced by obesity-attendant comorbidities. Our objective was to better understand the complex relationship of obesity and its attendant comorbidities with sPTBs. STUDY DESIGN: A retrospective analysis utilizing maternally linked hospital and birth certificate records of 2 049 196 singleton California deliveries from 2007 to 2011. Adjusted relative risks (aRRs) for sPTBs were estimated using multivariate Poisson regression modeling...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28749415/association-between-toenail-magnesium-and-type-2-diabetes-in-chinese-adults
#8
Jiguo Zhang, Huijun Wang, Zhihong Wang, Ji Zhang, Bing Zhang
Previous studies have showed an inverse association between magnesium level and type 2 diabetes, but the results are inconsistent, and the evidence relates only to dietary and serum magnesium. Moreover, it is not certain how these findings are applicable to Asian people. This study was designed to examine the association between toenail magnesium and type 2 diabetes in Chinese adults. The sample was 5683 adults aged 18 years or older from the 2009 China Health and Nutrition Survey. We used hemoglobin A1c equal to or greater than 6...
July 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28749410/awareness-of-the-risk-of-exposure-to-infectious-material-and-the-behaviors-of-polish-paramedics-with-respect-to-the-hazards-from-blood-borne-pathogens-a-nationwide-study
#9
Anna Garus-Pakowska, Mariusz Górajski, Franciszek Szatko
(1) Background: To determine paramedics' frequency of contact with blood and other body fluids, as well as the analysis of knowledge of paramedics about blood-borne infections, their attitudes to patients infected with blood-borne viruses, and the post-exposure procedures implemented by paramedics; (2) Methods: An anonymous questionnaire among 190 paramedics working in various health care facilities in Poland (adjusted response rate, 76.3%); (3) Results: 78% of paramedics had contact with potentially infectious material at least several times a week...
July 27, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28749400/a-novel-approach-for-characterizing-variations-in-serum-peptides-in-rheumatic-heart-disease
#10
Xiaochen Wu, Qin Yue, Weikun Jia, Jinbao Zhang, Hui Ouyang, Dong Xin, Yingbin Xiao
BACKGROUND & OBJECTIVES: Acute rheumatic fever and rheumatic heart disease (RHD) are important public health problems in developing countries. In this study, peptidomic analyses on RHD patients and healthy individuals were performed to characterize variations in serum peptide levels using label-free quantitation approaches. METHODS: Blood samples were obtained from 160 healthy controls and 160 RHD patients. Of the 448 identified peptides, 272 were analyzed by two label-free mass spectrometry methods, the spectral count and spectral index...
March 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28749369/race-ethnicity-socioeconomic-status-residential-segregation-and-spatial-variation-in-noise-exposure-in-the-contiguous-united-states
#11
Joan A Casey, Rachel Morello-Frosch, Daniel J Mennitt, Kurt Fristrup, Elizabeth L Ogburn, Peter James
BACKGROUND: Prior research has reported disparities in environmental exposures in the United States, but, to our knowledge, no nationwide studies have assessed inequality in noise pollution. OBJECTIVES: We aimed to a) assess racial/ethnic and socioeconomic inequalities in noise pollution in the contiguous United States; and b) consider the modifying role of metropolitan level racial residential segregation. METHODS: We used a geospatial sound model to estimate census block group-level median () nighttime and daytime noise exposure and 90th percentile () daytime noise exposure...
July 25, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28749279/effects-of-tramadol-on-the-minimum-anesthetic-concentration-of-isoflurane-in-white-eyed-parakeets-psittacara-leucophthalmus
#12
André Escobar, Rozana Wendler da Rocha, Monica Midon, Ricardo Miyasaka de Almeida, Darcio Zangirolami Filho, Karin Werther
The aim of this study was to determine the minimum anesthetic concentration (MAC) of isoflurane, and to investigate if tramadol changes the isoflurane MAC in white-eyed parakeets (Psittacara leucophthalmus). Ten adult birds weighing 157 ± 9 g were anesthetized with isoflurane in oxygen under mechanical ventilation. Isoflurane concentration for the first bird was adjusted to 2.2%, and after 15 min an electrical stimulus was applied in the thigh area to observe the response (movement or nonmovement). Isoflurane concentration for the subsequent bird was increased by 10% if the previous bird moved, or decreased by 10% if the previous bird did not move...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749259/management-of-pododermatitis-with-an-orthotic-boot-in-a-southern-isabela-giant-tortoise-chelonoidis-vicina
#13
Lynnette Waugh, Jennifer D'Agostino, Gretchen A Cole, Alicia Hahn, Jonathan D Day
A 62-yr-old male Southern Isabela giant tortoise (Chelonoidis vicina) had a 1-yr history of chronic, reoccurring pododermatitis on the palmar surface of the left forelimb. Aggressive wound management was instituted and included surgical debridement, vacuum-assisted closure, and orthotic boot support during healing. A custom fabricated, carbon fiber clamshell Charcot Restraint Orthotic Walker walking boot was utilized to reduce focal pressure over the wound during weight bearing and promote a more normal gait...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749255/pharmacokinetics-of-orally-administered-voriconazole-in-african-penguins-spheniscus-demersus-after-single-and-multiple-doses
#14
Michael W Hyatt, Nathan P Wiederhold, William W Hope, Katharine E Stott
Aspergillosis is a common respiratory fungal disease in African penguins ( Spheniscus demersus ) under managed care, and treatment failures with itraconazole due to drug resistance are increasingly common, leading to recent use of voriconazole. Empirical dosing with voriconazole based on other avian studies has resulted in adverse clinical drug effects in penguins. The objective of this study was to determine oral voriconazole pharmacokinetics (PK) in African penguins (n = 18). Single and once daily multiple oral doses of 5 mg/kg voriconazole were evaluated with a 4-mo washout period between trials...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749163/development-of-a-paediatric-head-voxel-model-database-for-dosimetric-applications
#15
Andreas Stratis, Nathan Touyz, Guozhi Zhang, Reinhilde Jacobs, Ria Bogaerts, Hilde Bosmans
OBJECTIVES: To develop a database of paediatric head voxel models intended for Monte Carlo (MC) dosimetric applications. METHODS: Seventeen head and neck CT image datasets were retrieved from the Picture Archiving and Communicating System (PACS) of our hospital and were reformed into voxel models. Twenty two organs were segmented at each dataset. The segmented organ masses were compared to the respective age and gender specific ICRP reference mass value. Adjustments were made such that segmented and reference mass values coincide within a tolerance of 10%...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749108/snp-and-haplotype-analysis-of-vascular-endothelial-growth-factor-vegf-gene-in-lung-cancer-patients-of-kashmir
#16
Niyaz A Naikoo, Dil Afroze, Roohi Rasool, Sonaullah Shah, A G Ahangar, Imtiyaz A Bhat, Iqbal Qasim, Mushtaq A Siddiqi, Zafar A Shah
Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving tumor growth and metastasis. In this large case-control study, we investigated whether functional polymorphisms (+405C>G, +936C>T) in the VEGF gene are associated with the risk of lung cancer. The study investigates the association between variants of VEGF gene and lung cancer. We performed single nucleotide polymorphism (SNP), haplotype and linkage disequilibrium studies on 100 patients and 128 healthy controls with 2 SNPs in the VEGF gene...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749103/decreased-mean-platelet-volume-is-associated-with-cervical-cancer-development
#17
Wen-Jie Shen, Shuang Fu, Na Li, Lu-Lu Li, Zhi-Gang Cao, Chuanfu Li, Tiemin Liu, Rui-Tao Wang
Background: Cervical cancer is the most common gynecological malignant disorder worldwide. Activated platelets play a key role in cancer development and progression. Mean platelet volume (MPV) is an early indicator of platelet activation. The aim of the present study was to evaluate MPV levels in patients with cervical cancer. Materials and methods: A total of 181 patients with cervical cancer and 181 controls between January 2015 and June 2015 were included in the study. Patient characteristics and hematologic test data at initial diagnosis were collected and odds ratios (ORs) and 95% confidence intervals (CIs) for risk of cervical cancer were calculated using multivariate logistic regression analyses across MPV quartiles...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749058/conservationism-and-bioethic
#18
EDITORIAL
Gregory E Kaebnick
The lead article in this issue of the Hastings Center Report (July-August 2017) explores the ideas underpinning the Precision Medicine Initiative, the effort announced by President Obama in 2015 to promote the development of treatments adjusted to genetic and other variations. Authors Maya Sabatello and Paul Appelbaum hold that the effort works by appealing to a sense of collective identity and shared commitment-an understanding that they call the "PMI nation." But what are the moral implications of this idea? Sabatello and Appelbaum's question about the impact of an imagined community is an unusual way of exploring a set of values questions...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28749019/the-association-of-non-alcoholic-fatty-liver-disease-with-lung-function-a-survey-design-analysis-using-propensity-score
#19
Min-Sun Kwak, Eunyoung Kim, Eun Jin Jang, Chang-Hoon Lee
BACKGROUND AND OBJECTIVE: Although both non-alcoholic fatty liver disease (NAFLD) and lung function are known to be associated with metabolic syndromes, few studies have evaluated the relationship between NAFLD and lung function. Our population-based study was conducted to investigate whether NAFLD, diagnosed by elevation of liver enzymes without other chronic liver disease or heavy alcohol drinking, is associated with lung function. METHODS: A survey design analysis was performed using national representative data of health and nutritional status of civilians in Korea (Korean National Health and Nutrition Examination Survey, KNHANES) between 2010 and 2012...
July 27, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28749017/large-institutional-variations-in-androgen-deprivation-therapy-utilization-with-definitive-radiotherapy-in-a-population-based-cohort-of-men-with-intermediate-and-high-risk-prostate-cancer
#20
Wee Loon Ong, Farshad Foroudi, Sue Evans, Jeremy Millar
OBJECTIVE: To evaluate the pattern of androgen deprivation therapy (ADT) utilization with definitive radiotherapy (RT) in men with prostate cancer (CaP) in a population-based study in Australia PATIENTS AND METHODS: This is a prospective cohort of men with intermediate and high-risk CaP captured in the population-based Prostate Cancer Outcome Registry Victoria (PCOR-Vic) treated with definitive prostate RT between January 2010 and December 2015. The primary outcome of interest is ADT utilization...
July 27, 2017: BJU International
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