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General internal medicine

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https://www.readbyqxmd.com/read/29236097/a-randomized-cohort-controlled-trial-to-compare-intern-sign-out-training-interventions
#1
Soo-Hoon Lee, Christopher Terndrup, Phillip H Phan, Sandra E Zaeh, Kwame Atsina, Nicole Minkove, Alexander Billioux, Souvik Chatterjee, Idoreyin Montague, Bennett Clark, Andrew Hughes, Sanjay V Desai
BACKGROUND: Although previous studies have investigated the efficacy of specific sign-out protocols (such as the illness severity, patient summary, action list, situation awareness and contingency planning, and synthesis by reviewer [I-PASS] bundle), the implementation of a bundle can be time consuming and costly. We compared 4 sign-out training pedagogies on sign-out quality. OBJECTIVE: To evaluate training interventions that best enhance multidimensional sign-out quality measured by information exchange, task accountability, and personal responsibility...
December 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29228989/physicians-lack-of-knowledge-a-possible-reason-for-red-blood-cell-transfusion-overuse
#2
Roni Rahav Koren, Celia Suriu, Orly Yakir, Luiza Akria, Masad Barhoum, Andrei Braester
BACKGROUND: A significant percentage of red blood cell transfusions are inappropriately overused. This study investigated physicians from the western Galilee in terms of their knowledge of transfusion medicine as a potential reason for red blood cell overuse, and assessed the influence of personal background characteristics on their knowledge. METHODS: Data were collected via anonymous questionnaires. The questionnaires included a personal background section and a professional section...
December 12, 2017: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/29228410/clinical-course-of-eosinophilic-cellulitis
#3
Hideki Ozawa, Kousuke Kuwano, Saki Manabe, Toru Ishihara, Masamichi Komatsu, Takako Kobayashi, Hidetaka Yanagi, Masayuki Oki, Atsushi Takagi
The patient was a previously healthy 23-year-old woman who made an outpatient visit to our hospital's Department of General Internal Medicine after developing pain and edema of the lower legs a week earlier. The patient was diagnosed with eosinophilic cellulitis (EC) based on an increased eosinophil count of 5,418/mm3 and the results of a skin biopsy of the lower leg that showed eosinophilic infiltration of the dermal tissue. Her condition improved after oral prednisone therapy. EC presents clinically as edema and eosinophilia...
December 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/29222988/medically-unexplained-physical-symptoms-in-patients-attending-a-medical-outpatient-clinic-in-a-tertiary-hospital-in-north-india
#4
Mohit Sharma, Shubh Mohan Singh, Ajit Avasthi, Subhash C Varma, Aman Sharma, Vikas Suri
OBJECTIVE: Medically unexplained physical symptoms (MUPS) are commonly seen across health care settings. Earlier studies have focussed on prevalence, cost-utilization and burden. Data from India is scarce. Patients with persistent MUPS have more impairment and psychological distress. This study was designed to assess psychological morbidity, health anxiety (HA), somatic symptom load, disability, quality of life (QOL) in patients with persistent MUPS presenting to a general medical outpatient service and compare it with patients with medically explained physical symptoms (MEPS)...
December 2, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29222179/hpv-vaccination-rate-in-french-adolescent-girls-an-example-of-vaccine-distrust
#5
Hervé Lefèvre, Cécile Schrimpf, Marie Rose Moro, Jonathan Lachal
OBJECTIVES: To explore the clinical issues of human papillomavirus (HPV) vaccination to develop explanatory hypotheses for the low level of vaccination among adolescent girls in France where the full course coverage is low (<15%). DESIGN: We used semistructured interviews. Our qualitative and phenomenological procedure applied interpretative phenomenological analysis. PARTICIPANTS: 16 physicians regularly faced with the prescription of HPV vaccine, represented several medical specialties (paediatrics, general practice, internal medicine, gynaecology), with hospitalist or private practices...
December 8, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29218803/community-pharmacist-led-clinical-services-physician-s-understanding-perceptions-and-readiness-to-collaborate-in-a-midwestern-state-in-the-united-states
#6
Cameron Gordon, Elizabeth Unni, Jaime Montuoro, Diane B Ogborn
OBJECTIVES: Many pharmacists are actively enhancing their role in the delivery of health care by offering a variety of pharmacist-led clinical services. The delivery of these services within community pharmacies can contribute to overcoming the cost and accessibility challenges currently facing U.S. health care, especially when pharmacist-physician collaborative efforts are utilized. The study purpose was to identify general and family practice physicians' awareness of pharmacists' delivery of clinical services, uncover their perceived barriers to collaboration with community pharmacists, and collect their input on how to overcome such barriers in order to better understand how pharmacist-led clinical services can be integrated, improved and more widely utilized as a healthcare delivery mechanism...
December 7, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29214389/using-real-world-data-in-health-technology-assessment-hta-practice-a-comparative-study-of-five-hta-agencies
#7
Amr Makady, Ard van Veelen, Páll Jonsson, Owen Moseley, Anne D'Andon, Anthonius de Boer, Hans Hillege, Olaf Klungel, Wim Goettsch
BACKGROUND: Reimbursement decisions are conventionally based on evidence from randomised controlled trials (RCTs), which often have high internal validity but low external validity. Real-world data (RWD) may provide complimentary evidence for relative effectiveness assessments (REAs) and cost-effectiveness assessments (CEAs). This study examines whether RWD is incorporated in health technology assessment (HTA) of melanoma drugs by European HTA agencies, as well as differences in RWD use between agencies and across time...
December 6, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29212336/-new-directions-in-bariatric-and-metabolic-surgery
#8
Martin Fried
Czech Republic may be counted among the leading European Countries in regards of the level of delivered high quality multidisciplinary care in treatment of obesity and obesity related metabolic diseases. The 1st Faculty of Medicine (Charles University) and the Faculty General Hospital in Prague played the most important role in the development of bariatric and metabolic surgery in the Czech Republic. pCzech bariatric surgery achieves great successes both on national and international levels. Just to mention some of them: M...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29209722/association-between-treatment-by-locum-tenens-internal-medicine-physicians-and-30-day-mortality-among-hospitalized-medicare-beneficiaries
#9
Daniel M Blumenthal, Andrew R Olenski, Yusuke Tsugawa, Anupam B Jena
Importance: Use of locum tenens physicians has increased in the United States, but information about their quality and costs of care is lacking. Objective: To evaluate quality and costs of care among hospitalized Medicare beneficiaries treated by locum tenens vs non-locum tenens physicians. Design, Setting, and Participants: A random sample of Medicare fee-for-service beneficiaries hospitalized during 2009-2014 was used to compare quality and costs of hospital care delivered by locum tenens and non-locum tenens internal medicine physicians...
December 5, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29209663/electronic-medical-record-alert-improves-hcv-testing-for-baby-boomers-in-primary-care-setting-adults-born-during-1945-1965
#10
Eyad Al-Hihi, Caylin Shankweiler, David Stricklen, Cheryl Gibson, Winston Dunn
Method: This project aims to implement the HCV birth cohort screening guidelines over a 9-month period in the primary care setting at the University of Kansas Health System General Internal Medicine Division. The project team measured the number of patients in the baby boomer population who received a one-time screen for HCV. An electronic medical record (EMR) intervention was implemented to identify baby boomers who did not have an HCV screening or diagnosis. Additionally, education was provided to all primary care providers in the clinic to increase awareness of the HCV birth cohort screening...
2017: BMJ Open Quality
https://www.readbyqxmd.com/read/29207433/-from-the-history-of-the-german-society-of-internal-medicine-dgim-part-1-the-dgim-in-the-nazi-era
#11
Ralf Forsbach, Hans-Georg Hofer
51 years after its founding in 1882, the "Congress for Internal Medicine", 1920 renamed "German Society for Internal Medicine (DGIM)", fell into heavy water. While during the Kaiserreich and the Weimar Republic the medical care for the individual patient had never been seriously questioned, the proclaimed "Third Reich" brought fundamental changes. The 1164 male and 13 female physicians, who had been organized in the DGIM 1933, had to position themselves in the Nazi dictatorship. The same applied for the society as a whole...
December 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29202742/milestones-based-direct-observation-tools-in-internal-medicine-resident-continuity-clinic
#12
Jonathan P B Berz, Teresa Cheng, Lisa M Quintiliani
BACKGROUND: With milestones-based assessment, there is an increased need for tools to facilitate direct observation of clinical trainees. This study was designed to compare a Mini-CEX tool to new direct observation tools (DOTs) linked to internal medicine milestones. METHODS: A web based survey was used to examine satisfaction and usefulness of DOTs compared to the Mini-CEX. Residents and preceptors were surveyed three times over 6 months with half serving as control (using mini-CEX) compared to those using the DOTs...
December 4, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29201110/presentation-of-a-novel-model-for-evaluation-of-commercialization-of-research-and-development-case-study-of-the-pharmaceutical-biotechnology-industry
#13
Hassan Emami, Reza Radfar
The current situation in Iran suggests an appropriate basis for developing biotechnology industries, because the patents for the majority of hi-tech medicines registered in developed countries are ending. Biosimilar and technology-oriented companies which do not have patents will have the opportunity to enter the biosimilar market and move toward innovative initiatives. The present research proposed a model by which one can evaluate commercialization of achievements obtained from research with a focus on the pharmaceutical biotechnology industry...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29200723/mice-behavioral-phenotype-changes-after-administration-of-anani-symphonia-globulifera-clusiaceae-an-alternative-latin-american-and-african-medicine
#14
Ivana Barbosa Suffredini, Mateus Luís Barradas Paciencia, Ingrit E C Díaz, Sergio Alexandre Frana, Maria Martha Bernardi
Background: Anani, (Symphonia globulifera, Clusiaceae), known as chewstick, is a traditional plant occurring in Africa and in Central and South Americas that is used against parasites and microorganisms. Although its use is popular in some of these countries, there is a lack of information related to its influence over behavioral phenotype (BP). Objective: The objective of this study is to evaluate the influence of the administration of the extract obtained from the aerial organs of Anani (EB1257) to male Balb-c mice over BP...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29197533/cervical-cancer-screening-uptake-among-hiv-positive-women-in-ontario-canada-a-population-based-retrospective-cohort-study
#15
Ann N Burchell, Claire E Kendall, Stephanie Y Cheng, Aisha Lofters, Michelle Cotterchio, Ahmed M Bayoumi, Richard H Glazier, Tony Antoniou, Janet Raboud, Mark H Yudin, Mona Loutfy
Cervical cancer caused by oncogenic types of the human papillomavirus (HPV) is of concern among HIV-positive women due to impairment of immune responses required to control HPV infection. Our objectives were to describe patterns of cervical cancer screening using Pap cytology testing among HIV-positive women in Ontario, Canada from 2008 to 2013 and to identify factors associated with adequate screening. We conducted a retrospective, population-based cohort study among screen-eligible HIV-positive women using provincial administrative health data...
November 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29196484/effect-of-herbal-extract-granules-combined-with-otilonium-bromide-on-irritable-bowel-syndrome-with-diarrhoea-a-study-protocol-for-a-randomised-controlled-trial
#16
Joong Il Kim, Pumsoo Kim, Jin-Hyun Lee, Yoo-Jin Kim, Na-Rae Yang, Myong Ki Baeg, Ja Sung Choi, Hye-Jung Kim, Jayoung Kim, Yun-Young Sunwoo, Jung-Han Lee, Hyekyung Ha, Tae-Yong Park
INTRODUCTION: Irritable bowel syndrome (IBS), known as a functional and organic gastrointestinal disorder, is a collection of symptoms that occur together and generally include pain or discomfort in the abdomen and changes in bowel movement patterns. Due to the limitations of conventional treatments, alternative IBS treatments are used by many patients worldwide. Samryungbaekchulsan (SRS), a herbal formula, has long been used for alleviating diarrhoea-predominant IBS (D-IBS) in traditional Korean medicine...
December 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/29196348/the-value-of-the-physical-examination-in-clinical-practice-an-international-survey
#17
Andrew T Elder, I Chris McManus, Alan Patrick, Kichu Nair, Louella Vaughan, Jane Dacre
A structured online survey was used to establish the views of 2,684 practising clinicians of all ages in multiple countries about the value of the physical examination in the contemporary practice of internal medicine. 70% felt that physical examination was 'almost always valuable' in acute general medical referrals. 66% of trainees felt that they were never observed by a consultant when undertaking physical examination and 31% that consultants never demonstrated their use of the physical examination to them...
December 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29193287/sensitivity-enhancement-for-detection-of-hyperpolarized-13-c-mri-probes-with-1-h-spin-coupling-introduced-by-enzymatic-transformation-in-vivo
#18
Cornelius von Morze, James Tropp, Albert P Chen, Irene Marco-Rius, Mark Van Criekinge, Timothy W Skloss, Daniele Mammoli, John Kurhanewicz, Daniel B Vigneron, Michael A Ohliger, Matthew E Merritt
PURPOSE: Although 1 H spin coupling is generally avoided in probes for hyperpolarized (HP) 13 C MRI, enzymatic transformations of biological interest can introduce large 13 C-1 H couplings in vivo. The purpose of this study was to develop and investigate the application of 1 H decoupling for enhancing the sensitivity for detection of affected HP 13 C metabolic products. METHODS: A standalone 1 H decoupler system and custom concentric 13 C/1 H paddle coil setup were integrated with a clinical 3T MRI scanner for in vivo 13 C MR studies using HP [2-13 C]dihydroxyacetone, a novel sensor of hepatic energy status...
November 28, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29192424/interventions-for-old-world-cutaneous-leishmaniasis
#19
REVIEW
Julio Heras-Mosteiro, Begoña Monge-Maillo, Mariona Pinart, Patricia Lopez Pereira, Ludovic Reveiz, Emely Garcia-Carrasco, Pedro Campuzano Cuadrado, Ana Royuela, Irene Mendez Roman, Rogelio López-Vélez
BACKGROUND: Cutaneous leishmaniasis, caused by a parasitic infection, is considered one of the most serious skin diseases in many low- and middle-income countries. Old World cutaneous leishmaniasis (OWCL) is caused by species found in Africa, Asia, the Middle East, the Mediterranean, and India. The most commonly prescribed treatments are antimonials, but other drugs have been used with varying success. As OWCL tends to heal spontaneously, it is necessary to justify the use of systemic and topical treatments...
December 1, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29191266/assessment-of-uv-spectrophotometry-for-determination-of-plasmid-dna-concentration-in-vector-preparations-for-human-gene-therapy-products
#20
X Chenivesse, B Anliker, A Daas, S Ferro, R Meier, M Renner, A Costanzo
The European Pharmacopoeia (Ph. Eur.) general chapter 5.14. Gene transfer medicinal products for human use suggests the use of absorbance measurements at 260 nm to determine the DNA concentration of plasmid vectors used for the preparation of gene therapy products for human use. An international collaborative study was organised by the European Directorate for the Quality of Medicines & HealthCare (EDQM) to confirm the suitability of UV spectrophotometry for the quantification of plasmid vectors used in gene therapy (GT)...
2017: Pharmeuropa Bio & Scientific Notes
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