keyword
https://read.qxmd.com/read/38585855/solicited-cough-sound-analysis-for-tuberculosis-triage-testing-the-coda-tb-dream-challenge-dataset
#21
Sophie Huddart, Vijay Yadav, Solveig K Sieberts, Larson Omberg, Mihaja Raberahona, Rivo Rakotoarivelo, Issa N Lyimo, Omar Lweno, Devasahayam J Christopher, Nguyen Viet Nhung, Grant Theron, William Worodria, Charles Y Yu, Christine M Bachman, Stephen Burkot, Puneet Dewan, Sourabh Kulhare, Peter M Small, Adithya Cattamanchi, Devan Jaganath, Simon Grandjean Lapierre
Cough is a common and commonly ignored symptom of lung disease. Cough is often perceived as difficult to quantify, frequently self-limiting, and non-specific. However, cough has a central role in the clinical detection of many lung diseases including tuberculosis (TB), which remains the leading infectious disease killer worldwide. TB screening currently relies on self-reported cough which fails to meet the World Health Organization (WHO) accuracy targets for a TB triage test. Artificial intelligence (AI) models based on cough sound have been developed for several respiratory conditions, with limited work being done in TB...
March 28, 2024: medRxiv
https://read.qxmd.com/read/38583345/how-nursing-students-perceptions-of-people-with-psychiatric-disabilities-change-when-using-the-strengths-model-during-practicums-a-qualitative-research-study
#22
JOURNAL ARTICLE
Miho Katayama, Ritsuko Aijo, Kazuyo Kitaoka, Megumi Kawaguchi
BACKGROUND: The Strengths Model, a framework grounded in the belief that everyone has an inherent capability to cope with challenges, is designed to support the hopes and aspirations of people with psychiatric disabilities, guiding them toward their desired self-image. The model originally gained attention in the field of social welfare and has since become popular in the field of community mental health. There is an increasing demand for nurses to understand and implement this model in the support they provide...
April 3, 2024: Nurse Education Today
https://read.qxmd.com/read/38578827/neural-assemblies-coordinated-by-cortical-waves-are-associated-with-waking-and-hallucinatory-brain-states
#23
JOURNAL ARTICLE
Adeeti Aggarwal, Jennifer Luo, Helen Chung, Diego Contreras, Max B Kelz, Alex Proekt
The relationship between sensory stimuli and perceptions is brain-state dependent: in wakefulness, suprathreshold stimuli evoke perceptions; under anesthesia, perceptions are abolished; and during dreaming and in dissociated states, percepts are internally generated. Here, we exploit this state dependence to identify brain activity associated with internally generated or stimulus-evoked perceptions. In awake mice, visual stimuli phase reset spontaneous cortical waves to elicit 3-6 Hz feedback traveling waves...
April 3, 2024: Cell Reports
https://read.qxmd.com/read/38578260/ontological-psychoanalysis-in-clinical-practice
#24
JOURNAL ARTICLE
Thomas H Ogden
The author describes and then clinically illustrates what he terms the ontological dimension of psychoanalysis (having to do with coming into being) and the epistemological dimension of psychoanalysis (having to do with coming to know and understand). Neither of these dimensions of psychoanalysis exists in pure form; they are inextricably intertwined. Epistemological psychoanalysis, for which Freud and Klein are the principal architects, involves the work of arriving at understandings of play, dreams, and associations; while ontological psychoanalysis, for which Winnicott and Bion are the principal architects, involves creating conditions in which the patient might become more fully alive and real to him- or herself...
2024: Psychoanalytic Quarterly
https://read.qxmd.com/read/38574727/the-neuroscience-of-lucid-dreaming-past-present-future
#25
JOURNAL ARTICLE
Paul Zerr, Nico Adelhöfer, Martin Dresler
Lucid dreaming allows conscious awareness and control of vivid dream states; however, its rarity and instability make neuroscientific experimentation challenging. Recent advances in wearable neurotechnology, large-scale collaborations, citizen neuroscience, and artificial intelligence increasingly facilitate the decoding of this intriguing phenomenon.
April 3, 2024: Neuron
https://read.qxmd.com/read/38570779/how-men-influence-young-women-taking-prep-perspectives-from-young-women-male-partners-and-male-peers-in-siaya-county-western-kenya
#26
JOURNAL ARTICLE
Kawango Agot, Jacob Onyango, Brian Perry, Nneka Molokwu, Jamilah Taylor, Duncan Ngoje, Amy Corneli
BACKGROUND: Daily oral pre-exposure prophylaxis (PrEP) is an effective HIV prevention option for those who are most vulnerable to HIV infection, especially young women (YW). Objection by or lack of support from male sexual partners has been shown to impact YW's ability to take PrEP consistently. We explored the views of YW, and male partners and male peers of YW in Siaya County, Western Kenya, to illustrate how men influence, and can support, YW in using PrEP. METHODS: We used Photovoice to capture the views of YW ages 18-24 who were currently or previously enrolled in the DREAMS program and with current or previous experience taking PrEP...
April 3, 2024: BMC Women's Health
https://read.qxmd.com/read/38570626/the-high-fkbp1a-expression-in-wbcs-as-a-potential-screening-biomarker-for-pancreatic-cancer
#27
JOURNAL ARTICLE
Papitchaya Watcharanurak, Apiwat Mutirangura, Vitavat Aksornkitti, Narumol Bhummaphan, Charoenchai Puttipanyalears
Given the limitation of current routine approaches for pancreatic cancer screening and detection, the mortality rate of pancreatic cancer cases is still critical. The development of blood-based molecular biomarkers for pancreatic cancer screening and early detection which provide less-invasive, high-sensitivity, and cost-effective, is urgently needed. The goal of this study is to identify and validate the potential molecular biomarkers in white blood cells (WBCs) of pancreatic cancer patients. Gene expression profiles of pancreatic cancer patients from NCBI GEO database were analyzed by CU-DREAM...
April 3, 2024: Scientific Reports
https://read.qxmd.com/read/38568049/the-dream-of-a-diagnosis
#28
JOURNAL ARTICLE
Golda Grinberg
No abstract text is available yet for this article.
April 3, 2024: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://read.qxmd.com/read/38564922/sleep-related-adverse-events-of-smoking-cessation-drugs-a-network-meta-analysis-of-randomized-controlled-trials
#29
REVIEW
Yubin Song, Yoon-A Park, Da Hoon Lee, Jeong Yee, Hye Sun Gwak
Smoking cessation medications have the potential to affect the functioning of the nervous system, leading to sleep disturbances. Our study aimed to compare the sleep-related side effects (such as insomnia, abnormal dreams, nightmares, and somnolence) induced by different smoking cessation medications in non-psychiatric smokers. We conducted a thorough search of five electronic databases (Cochrane, EMBASE, PubMed, PsycInfo, and Web of Science) for randomized controlled trials. This study was registered with the PROSPERO (registration number CRD42022347976)...
March 29, 2024: Psychiatry Research
https://read.qxmd.com/read/38564857/aphantasia-and-involuntary-imagery
#30
REVIEW
Raquel Krempel, Merlin Monzel
Aphantasia is a condition that is often characterized as the impaired ability to create voluntary mental images. Aphantasia is assumed to selectively affect voluntary imagery mainly because even though aphantasics report being unable to visualize something at will, many report having visual dreams. We argue that this common characterization of aphantasia is incorrect. Studies on aphantasia are often not clear about whether they are assessing voluntary or involuntary imagery, but some studies show that several forms of involuntary imagery are also affected in aphantasia (including imagery in dreams)...
April 1, 2024: Consciousness and Cognition
https://read.qxmd.com/read/38561607/potential-serotonin-5-ht2a-receptor-agonist-of-psychoactive-components-of-silene-undulata-aiton-lc-ms-ms-admet-and-molecular-docking-studies
#31
JOURNAL ARTICLE
Maram B Alhawarri, Suleiman Olimat
BACKGROUND: Silene undulata is historically used for inducing vivid and prophetic lucid dreams, but limited information exists on its phytochemical composition and potential pharmacological properties. OBJECTIVE: This study aimed to investigate the phytochemical composition of S. undulata through LC-MS/MS analysis and explore its potential serotonergic activity, which could support and confirm the traditional use of S. undulata as a dream-inducing plant. METHODS: LC-MS/MS analysis was conducted on S...
March 29, 2024: Current Pharmaceutical Biotechnology
https://read.qxmd.com/read/38558050/synthesizing-avian-dreams
#32
JOURNAL ARTICLE
Juan F Döppler, Melina Atencio, Ana Amador, Gabriel B Mindlin
During sleep, sporadically, it is possible to find neural patterns of activity in areas of the avian brain that are activated during the generation of the song. It has recently been found that in the vocal muscles of a sleeping bird, it is possible to detect activity patterns during these silent replays. In this work, we employ a dynamical systems model for song production in suboscine birds in order to translate the vocal muscles activity during sleep into synthetic songs. Besides allowing us to translate muscle activity into behavior, we argue that this approach poses the biomechanics as a unique window into the avian brain, with biophysical models as its probe...
April 1, 2024: Chaos
https://read.qxmd.com/read/38553503/orbital-reef-and-commercial-low-earth-orbit-destinations-upcoming-space-research-opportunities
#33
REVIEW
Luis Zea, Liz Warren, Tara Ruttley, Todd Mosher, Laura Kelsey, Erika Wagner
As the International Space Station comes to the end of a transformative era of in-space research, NASA's Commercial Low Earth Orbit (LEO) Destinations (CLD) Program aims to catalyze a new generation of platforms with co-investment from the private sector, preventing a potential gap in research performed in LEO, while building a robust LEO economy. In this paper, we provide insight into the CLD Program focusing on Orbital Reef, describing its operational and technical characteristics as well as new opportunities it may enable...
March 29, 2024: NPJ Microgravity
https://read.qxmd.com/read/38551661/was-it-just-a-dream-aging-and-dreaming-the-psychoanalytic-process
#34
JOURNAL ARTICLE
Anneli Larmo
By revisiting the last years of a long psychoanalytic treatment of a female patient, a psychoanalyst reflects on her own development as a clinician and on the changes in her experience of psychoanalytic generativity. An increasing ability to understand patient's shifts between creativity and destructiveness brings about a different understanding of the process of mourning, while the shared aging of the analytic dyad highlights the difficulty of ending an analysis that has become a way of life.
March 2024: Psychoanalytic Review
https://read.qxmd.com/read/38551276/after-a-wealth-of-welfare-experience-i-landed-my-dream-job-at-the-donkey-sanctuary
#35
JOURNAL ARTICLE
Jo Hockenhull
From an early age Jo Hockenhull was acutely aware of the plight of equids and how animals' behaviour reveals a huge amount about their wellbeing, leading to a distinguished career in animal welfare research.
March 2024: Veterinary Record
https://read.qxmd.com/read/38548974/how-a-spreadsheet-helped-me-to-land-my-dream-job
#36
Silvia Sanasi
No abstract text is available yet for this article.
March 28, 2024: Nature
https://read.qxmd.com/read/38548492/aphantasia-and-hyperphantasia-exploring-imagery-vividness-extremes
#37
REVIEW
Adam Zeman
The vividness of imagery varies between individuals. However, the existence of people in whom conscious, wakeful imagery is markedly reduced, or absent entirely, was neglected by psychology until the recent coinage of 'aphantasia' to describe this phenomenon. 'Hyperphantasia' denotes the converse - imagery whose vividness rivals perceptual experience. Around 1% and 3% of the population experience extreme aphantasia and hyperphantasia, respectively. Aphantasia runs in families, often affects imagery across several sense modalities, and is variably associated with reduced autobiographical memory, face recognition difficulty, and autism...
March 9, 2024: Trends in Cognitive Sciences
https://read.qxmd.com/read/38548360/how-can-we-improve-comprehensive-geriatric-assessment-for-older-people-living-with-frailty-in-primary-care-and-community-settings-a-qualitative-study
#38
JOURNAL ARTICLE
Aseel Mahmoud, Victoria A Goodwin, Naomi Morley, Julie Whitney, Sarah E Lamb, Helen Lyndon, Siobhan Creanor, Julia Frost
OBJECTIVE: With advancing age comes the increasing prevalence of frailty and increased risk of adverse outcomes (eg, hospitalisation). Evidence for comprehensive geriatric assessment (CGA), a multidimensional holistic model of care, is mixed in community settings. Uncertainties remain, such as the key components of CGA, who delivers it, and the use of technology. This study aimed to understand the perspectives, beliefs and experiences, of both older people and health professionals, to improve the current CGA and explore factors that may impact on CGA delivery in community settings...
March 28, 2024: BMJ Open
https://read.qxmd.com/read/38547282/the-dream-machine
#39
Adrian Cho
An accelerator known as a muon collider could revolutionize particle physics-if it can be built.
March 29, 2024: Science
https://read.qxmd.com/read/38546944/a-phase-1-study-of-intravenous-egfr-erbituxedvsmit-in-children-with-solid-or-cns-tumours-expressing-epidermal-growth-factor-receptor
#40
JOURNAL ARTICLE
Louise Evans, Rick Walker, Jennifer MacDiarmid, Himanshu Brahmbhatt, Antoinette Anazodo, Geoffrey McCowage, Andrew J Gifford, Maria Kavallaris, Toby Trahair, David S Ziegler
BACKGROUND: Recurrent or refractory solid and central nervous system (CNS) tumours in paediatric patients have limited treatment options and carry a poor prognosis. The EnGeneIC Dream Vector (EDV) is a novel nanocell designed to deliver cytotoxic medication directly to the tumour. The epidermal growth factor receptor is expressed in several CNS and solid tumours and is the target for bispecific antibodies attached to the EDV. OBJECTIVE: To assess the safety and tolerability of EGFR-Erbitux receptor EnGeneIC Dream Vector with mitoxantrone (E EDVsMit ) in children with recurrent / refractory solid or CNS tumours expressing EGFR...
March 28, 2024: Targeted Oncology
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