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https://www.readbyqxmd.com/read/28534169/-capacity-to-consent-to-treatment-in-dementia-patients-interdisciplinary-perspectives
#1
REVIEW
Julia Haberstroh, Tanja Müller
BACKGROUND: Currently, there are no concrete, evidence-based default procedures to adequately assess the capacity to consent to medical treatment. This explains why different raters use individual heuristics, differing both within and between disciplines. The lack of a procedure that is standardized, validated, and equally accepted across disciplines to assess the capacity to consent to treatment has led to an uncertainty in legal and medical practice regarding appropriate action and decision making...
May 22, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28472938/exploring-generative-mechanisms-of-the-antiretroviral-adherence-club-intervention-using-the-realist-approach-a-scoping-review-of-research-based-antiretroviral-treatment-adherence-theories
#2
Ferdinand C Mukumbang, Sara Van Belle, Bruno Marchal, Brian van Wyk
BACKGROUND: Poor retention in care and non-adherence to antiretroviral therapy (ART) continue to undermine the success of HIV treatment and care programmes across the world. There is a growing recognition that multifaceted interventions - application of two or more adherence-enhancing strategies - may be useful to improve ART adherence and retention in care among people living with HIV/AIDS. Empirical evidence shows that multifaceted interventions produce better results than interventions based on a singular perspective...
May 4, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28438724/toward-a-more-usable-home-based-video-telemedicine-system-a-heuristic-evaluation-of-the-clinician-user-interfaces-of-home-based-video-telemedicine-systems
#3
Sruthy Agnisarman, Shraddhaa Narasimha, Kapil Chalil Madathil, Brandon Welch, Fnu Brinda, Aparna Ashok, James McElligott
BACKGROUND: Telemedicine is the use of technology to provide and support health care when distance separates the clinical service and the patient. Home-based telemedicine systems involve the use of such technology for medical support and care connecting the patient from the comfort of their homes with the clinician. In order for such a system to be used extensively, it is necessary to understand not only the issues faced by the patients in using them but also the clinician. OBJECTIVES: The aim of this study was to conduct a heuristic evaluation of 4 telemedicine software platforms-Doxy...
April 24, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28413365/integrating-the-principles-of-evidence-based-medicine-and-evidence-based-public-health-impact-on-the-quality-of-patient-care-and-hospital-readmission-rates-in-jordan
#4
Mohammad S Alyahya, Heba H Hijazi, Hussam A Alshraideh, Mohammad Aser Alsharman, Rabah Al Abdi, Heather Lea Harvey
INTRODUCTION: Hospital readmissions impose not only an extra burden on health care systems but impact patient health outcomes. Identifying modifiable behavioural risk factors that are possible causes of potentially avoidable readmissions can lower readmission rates and healthcare costs. METHODS: Using the core principles of evidence based medicine and public health, the purpose of this study was to develop a heuristic guide that could identify what behavioural risk factors influence hospital readmissions through adopting various methods of analysis including regression models, t-tests, data mining, and logistic regression...
August 31, 2016: International Journal of Integrated Care
https://www.readbyqxmd.com/read/28394995/video-analysis-of-factors-associated-with-response-time-to-physiologic-monitor-alarms-in-a-children-s-hospital
#5
Christopher P Bonafide, A Russell Localio, John H Holmes, Vinay M Nadkarni, Shannon Stemler, Matthew MacMurchy, Miriam Zander, Kathryn E Roberts, Richard Lin, Ron Keren
Importance: Bedside monitor alarms alert nurses to life-threatening physiologic changes among patients, but the response times of nurses are slow. Objective: To identify factors associated with physiologic monitor alarm response time. Design, Setting, and Participants: This prospective cohort study used 551 hours of video-recorded care administered by 38 nurses to 100 children in a children's hospital medical unit between July 22, 2014, and November 11, 2015...
April 10, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28368826/sparse-pathway-induced-dynamic-network-biomarker-discovery-for-early-warning-signal-detection-in-complex-diseases
#6
Abolfazl Doostparast Torshizi, Linda Petzold
In many complex diseases, the transition process from healthy stage to catastrophic stage does not occur gradually. Recent studies indicate that the initiation and progression of such diseases are comprised of three steps including healthy stage, pre-disease stage, and disease stage. It has been demonstrated that a certain set of trajectories can be observed in the genetic signatures at the molecular level, which might be used to detect the pre-disease stage and to take necessary medical interventions. In this paper, we propose two optimization-based algorithms for extracting the dynamic network biomarkers responsible for catastrophic transition into the disease stage, and to open new horizons to reverse the disease progression at an early stage through pinpointing molecular signatures provided by high-throughput microarray data...
March 27, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28329465/youtube-as-a-source-of-health-information-analysis-of-sun-protection-and-skin-cancer-prevention-related-issues
#7
Linda Ruppert, Brian Køster, Anna Maria Siegert, Christian Cop, Lindsay Boyers, Chante Karimkhani, Helena Winston, Jessica Mounessa, Robert P Dellavalle, Daphne Reinau, Thomas Diepgen, Christian Surber
Although social media ubiquitously supplementstraditional information sources such as newspapers,magazines, radio, and television, investigation of onlinehealth information related to sun protection and skincancer prevention has been scarce and largely limitedto English language sources. Using the search terms"sun protection," "sunscreen," "skin cancer prevention,"tanning bed" and "vitamin D," we investigated 281YouTube videos presented in 6 languages: English,German, French, Spanish, Swedish, and Danish. Foreach video, we used a four-sectioned checklist toassess general information, popularity, expert drivenmeasures, and heuristic driven measures...
January 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328885/introducing-therioepistemology-the-study-of-how-knowledge-is-gained-from-animal-research
#8
REVIEW
Joseph P Garner, Brianna N Gaskill, Elin M Weber, Jamie Ahloy-Dallaire, Kathleen R Pritchett-Corning
This focus issue of Lab Animal coincides with a tipping point in biomedical research. For the first time, the scale of the reproducibility and translatability crisis is widely understood beyond the small cadre of researchers who have been studying it and the pharmaceutical and biotech companies who have been living it. Here we argue that an emerging literature, including the papers in this focus issue, has begun to congeal around a set of recurring themes, which themselves represent a paradigm shift. This paradigm shift can be characterized at the micro level as a shift from asking "what have we controlled for in this model?" to asking "what have we chosen to ignore in this model, and at what cost?" At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study...
March 22, 2017: Lab Animal
https://www.readbyqxmd.com/read/28269240/automated-abo-rh-d-blood-type-detection-using-smartphone-imaging-for-point-of-care-medical-diagnostics
#9
Neha Srivathsa, Dhananjaya Dendukuri
We present a novel methodology for automated ABO Rh-D blood typing using simple morphological image processing algorithms to be used in conjunction with a fabric strip based rapid diagnostic test. Images of the fabric strip post testing are acquired using low cost mobile phones and the proposed algorithm proceeds to automatically identify the blood type by processing the images using steps comprising of noise reduction, range filtering and empirically derived heuristics. The ultimate goal is to provide a simple mobile phone application to enable automated, rapid and accessible blood type detection at the point-of-care...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269081/an-adapted-double-threshold-protocol-for-spastic-muscles
#10
Pedro M Vieira, Joao F Ferreira, Pedro R Gomes, Carlos S Lima
The onset of muscle contraction has been an important element in the understanding of human motor control system as well as in the development of medical devices. This task is problematic in the study of spasticity using surface Electromyography (sEMG). In fact, spasticity is characterized by involuntary muscle contractions that can be seen as both, a non-stationary background if they are weak or a severe non-stationary EMG signal if they are strong. In other hand, these sEMG signals present a very low signal to noise ratio, beyond the added noise that contaminates this signal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227474/automated-abo-rh-d-blood-type-detection-using-smartphone-imaging-for-point-of-care-medical-diagnostics
#11
Neha Srivathsa, Dhananjaya Dendukuri, Neha Srivathsa, Dhananjaya Dendukuri, Neha Srivathsa, Dhananjaya Dendukuri
We present a novel methodology for automated ABO Rh-D blood typing using simple morphological image processing algorithms to be used in conjunction with a fabric strip based rapid diagnostic test. Images of the fabric strip post testing are acquired using low cost mobile phones and the proposed algorithm proceeds to automatically identify the blood type by processing the images using steps comprising of noise reduction, range filtering and empirically derived heuristics. The ultimate goal is to provide a simple mobile phone application to enable automated, rapid and accessible blood type detection at the point-of-care...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227301/an-adapted-double-threshold-protocol-for-spastic-muscles
#12
Pedro M Vieira, Joao F Ferreira, Pedro R Gomes, Carlos S Lima, Pedro M Vieira, Joao F Ferreira, Pedro R Gomes, Carlos S Lima, Pedro M Vieira, Joao F Ferreira, Pedro R Gomes, Carlos S Lima
The onset of muscle contraction has been an important element in the understanding of human motor control system as well as in the development of medical devices. This task is problematic in the study of spasticity using surface Electromyography (sEMG). In fact, spasticity is characterized by involuntary muscle contractions that can be seen as both, a non-stationary background if they are weak or a severe non-stationary EMG signal if they are strong. In other hand, these sEMG signals present a very low signal to noise ratio, beyond the added noise that contaminates this signal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28105927/candidate-snp-markers-of-aggressiveness-related-complications-and-comorbidities-of-genetic-diseases-are-predicted-by-a-significant-change-in-the-affinity-of-tata-binding-protein-for-human-gene-promoters
#13
Irina V Chadaeva, Mikhail P Ponomarenko, Dmitry A Rasskazov, Ekaterina B Sharypova, Elena V Kashina, Marina Yu Matveeva, Tatjana V Arshinova, Petr M Ponomarenko, Olga V Arkova, Natalia P Bondar, Ludmila K Savinkova, Nikolay A Kolchanov
BACKGROUND: Aggressiveness in humans is a hereditary behavioral trait that mobilizes all systems of the body-first of all, the nervous and endocrine systems, and then the respiratory, vascular, muscular, and others-e.g., for the defense of oneself, children, family, shelter, territory, and other possessions as well as personal interests. The level of aggressiveness of a person determines many other characteristics of quality of life and lifespan, acting as a stress factor. Aggressive behavior depends on many parameters such as age, gender, diseases and treatment, diet, and environmental conditions...
December 28, 2016: BMC Genomics
https://www.readbyqxmd.com/read/28089814/prospects-and-problems-for-standardizing-model-validation-in-systems-biology
#14
REVIEW
Fridolin Gross, Miles MacLeod
There are currently no widely shared criteria by which to assess the validity of computational models in systems biology. Here we discuss the feasibility and desirability of implementing validation standards for modeling. Having such a standard would facilitate journal review, interdisciplinary collaboration, model exchange, and be especially relevant for applications close to medical practice. However, even though the production of predictively valid models is considered a central goal, in practice modeling in systems biology employs a variety of model structures and model-building practices...
January 12, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28088527/navigation-in-the-electronic-health-record-a-review-of-the-safety-and-usability-literature
#15
REVIEW
Lisette C Roman, Jessica S Ancker, Stephen B Johnson, Yalini Senathirajah
OBJECTIVE: Inefficient navigation in electronic health records has been shown to increase users' cognitive load, which may increase potential for errors, reduce efficiency, and increase fatigue. However, navigation has received insufficient recognition and attention in the electronic health record (EHR) literature as an independent construct and contributor to overall usability. Our aims in this literature review were to (1) assess the prevalence of navigation-related topics within the EHR usability and safety research literature, (2) categorize types of navigation actions within the EHR, (3) capture relationships between these navigation actions and usability principles, and (4) collect terms and concepts related to EHR navigation...
January 11, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28048700/tu-d-bra-00-treatment-planning-system-commissioning-and-qa
#16
Greg Salomons
INTRODUCTION: Treatment planning systems (TPS) are a cornerstone of modern radiation therapy. Errors in their commissioning or use can have a devastating impact on many patients. To support safe and high quality care, medical physicists must conduct efficient and proper commissioning, good clinical integration, and ongoing quality assurance (QA) of the TPS. AAPM Task Group 53 and related publications have served as seminal benchmarks for TPS commissioning and QA over the past two decades...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048038/tu-d-bra-01-tps-commissioning-and-qa-planning-and-monitoring
#17
G Salomons
INTRODUCTION: Treatment planning systems (TPS) are a cornerstone of modern radiation therapy. Errors in their commissioning or use can have a devastating impact on many patients. To support safe and high quality care, medical physicists must conduct efficient and proper commissioning, good clinical integration, and ongoing quality assurance (QA) of the TPS. AAPM Task Group 53 and related publications have served as seminal benchmarks for TPS commissioning and QA over the past two decades...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047536/mo-ab-bra-01-a-global-level-set-based-formulation-for-volumetric-modulated-arc-therapy
#18
D Nguyen, Q Lyu, D Ruan, D O'Connor, D Low, K Sheng
PURPOSE: The current clinical Volumetric Modulated Arc Therapy (VMAT) optimization is formulated as a non-convex problem and various greedy heuristics have been employed for an empirical solution, jeopardizing plan consistency and quality. We introduce a novel global direct aperture optimization method for VMAT to overcome these limitations. METHODS: The global VMAT (gVMAT) planning was formulated as an optimization problem with an L2-norm fidelity term and an anisotropic total variation term...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047503/th-ef-brb-05-4pi-non-coplanar-imrt-beam-angle-selection-by-convex-optimization-with-group-sparsity-penalty
#19
D O'Connor, Y Voronenko, D Nguyen, W Yin, K Sheng
PURPOSE: Integrated beam orientation and fluence map optimization is expected to be the foundation of robust automated planning but existing heuristic methods do not promise global optimality. We aim to develop a new method for beam angle selection in 4π non-coplanar IMRT systems based on solving (globally) a single convex optimization problem, and to demonstrate the effectiveness of the method by comparison with a state of the art column generation method for 4π beam angle selection...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047373/tu-d-bra-02-recommendations-of-mppg-5-and-practical-implementation-strategies
#20
J Smilowitz
INTRODUCTION: Treatment planning systems (TPS) are a cornerstone of modern radiation therapy. Errors in their commissioning or use can have a devastating impact on many patients. To support safe and high quality care, medical physicists must conduct efficient and proper commissioning, good clinical integration, and ongoing quality assurance (QA) of the TPS. AAPM Task Group 53 and related publications have served as seminal benchmarks for TPS commissioning and QA over the past two decades...
June 2016: Medical Physics
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