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https://www.readbyqxmd.com/read/29770954/the-relationship-between-physical-impairments-quality-of-life-and-disability-of-the-neck-and-upper-limb-in-patients-following-neck-dissection
#1
Elise M Gane, Steven M McPhail, Anna L Hatton, Benedict J Panizza, Shaun P O'Leary
PURPOSE: The purpose of this study was to examine the relationship between physical impairments, quality of life and disability in patients following neck dissection, with consideration of patient and clinical characteristics. METHODS: Cross-sectional study of patients < 5 years after neck dissection for head and neck cancer. Quality of life and self-reported disability were measured with the Neck Dissection Impairment Index, Quick Disabilities of the Arm, Shoulder and Hand, and Neck Disability Index...
May 16, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29766628/health-professional-student-education-related-to-the-prevention-of-falls-in-older-people-a-survey-of-universities-in-australia-and-new-zealand
#2
Esther Vance, Melanie K Farlie, Bridget Kool, Anne Tiedemann, Anna L Hatton, Catherine Sherrington, Daina L Sturnieks
OBJECTIVE: To determine the amount and nature of health professional education related to fall prevention for older adults in Australian and New Zealand universities. METHODS: Universities offering medicine, nursing and allied health courses were invited to complete an online survey enquiring about fall prevention course-related information: topics; delivery mode; and time dedicated. RESULTS: One hundred and five respondents, 11 disciplines and 43 universities completed the survey...
May 15, 2018: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29758890/the-extent-of-tebuconazole-leaching-from-unpainted-and-painted-softwood
#3
Klara Kukowski, Joshua Hatton, Evguenii I Kozliak, Alena Kubátová
Exposure to water and high air humidity may affect the preservation of wood products as many preservatives are water-soluble and thus likely to leach. In this study, depletion of a common fungicide, tebuconazole (TAZ), from treated wood was investigated using a 14 C-labeled tracer. The wood species and treatment technique were chosen to be representative of products such as windows and doors; specifically, ponderosa pine was dip treated with a solvent-based, metal-free formulation. The impact of different aqueous settings including high air humidity, and either simulated continuous or intermittent rain was evaluated over a period of two months...
August 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29756848/strong-isospin-breaking-correction-to-the-muon-anomalous-magnetic-moment-from-lattice-qcd-at-the-physical-point
#4
B Chakraborty, C T H Davies, C DeTar, A X El-Khadra, E Gámiz, Steven Gottlieb, D Hatton, J Koponen, A S Kronfeld, J Laiho, G P Lepage, Yuzhi Liu, P B Mackenzie, C McNeile, E T Neil, J N Simone, R Sugar, D Toussaint, R S Van de Water, A Vaquero
All lattice-QCD calculations of the hadronic-vacuum-polarization contribution to the muon's anomalous magnetic moment to date have been performed with degenerate up- and down-quark masses. Here we calculate directly the strong-isospin-breaking correction to a_{μ}^{HVP} for the first time with physical values of m_{u} and m_{d} and dynamical u, d, s, and c quarks, thereby removing this important source of systematic uncertainty. We obtain a relative shift to be applied to lattice-QCD results obtained with degenerate light-quark masses of δa_{μ}^{HVP,m_{u}≠m_{d}}=+1...
April 13, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29754783/therapeutic-spaces-of-care-farming-transformative-or-ameliorating
#5
Alexandra Kaley, Chris Hatton, Christine Milligan
Since Wil Gesler's earliest articulation (Gesler, 1992; Gesler, 1996) key thinkers in the field of therapeutic landscapes have sought to emphasise the embodied, contextual and wholly relational nature of the relationship that exists between people and place. However, the extant research has tended to focus on the relational healing experience as this occurs 'in the moment' and with reference to a specific location or site of healing, with less attention being paid to what happens to people when they return to their ordinary or everyday places...
May 4, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29719605/-in-vivo-safety-and-efficacy-testing-of-a-thermally-triggered-injectable-hydrogel-scaffold-for-bone-regeneration-and-augmentation-in-a-rat-model
#6
Abbey A Thorpe, Christine Freeman, Paula Farthing, Jill Callaghan, Paul V Hatton, Ian M Brook, Chris Sammon, Christine Lyn Le Maitre
Bone loss resulting from degenerative diseases and trauma is a significant clinical burden which is likely to grow exponentially with the aging population. In a number of conditions where pre-formed materials are clinically inappropriate an injectable bone forming hydrogel could be beneficial. The development of an injectable hydrogel to stimulate bone repair and regeneration would have broad clinical impact and economic benefit in a variety of orthopedic clinical applications. We have previously reported the development of a Laponite® crosslinked pNIPAM-co-DMAc (L-pNIPAM-co-DMAc) hydrogel delivery system, loaded with hydroxyapatite nanoparticles (HAPna), which was capable of inducing osteogenic differentiation of mesenchymal stem cells (MSCs) without the need for additional growth factors in vitro ...
April 6, 2018: Oncotarget
https://www.readbyqxmd.com/read/29713086/carboplatin-in-brca1-2-mutated-and-triple-negative-breast-cancer-brcaness-subgroups-the-tnt-trial
#7
Andrew Tutt, Holly Tovey, Maggie Chon U Cheang, Sarah Kernaghan, Lucy Kilburn, Patrycja Gazinska, Julie Owen, Jacinta Abraham, Sophie Barrett, Peter Barrett-Lee, Robert Brown, Stephen Chan, Mitchell Dowsett, James M Flanagan, Lisa Fox, Anita Grigoriadis, Alexander Gutin, Catherine Harper-Wynne, Matthew Q Hatton, Katherine A Hoadley, Jyoti Parikh, Peter Parker, Charles M Perou, Rebecca Roylance, Vandna Shah, Adam Shaw, Ian E Smith, Kirsten M Timms, Andrew M Wardley, Gregory Wilson, Cheryl Gillett, Jerry S Lanchbury, Alan Ashworth, Nazneen Rahman, Mark Harries, Paul Ellis, Sarah E Pinder, Judith M Bliss
Germline mutations in BRCA1/2 predispose individuals to breast cancer (termed germline-mutated BRCA1/2 breast cancer, gBRCA-BC) by impairing homologous recombination (HR) and causing genomic instability. HR also repairs DNA lesions caused by platinum agents and PARP inhibitors. Triple-negative breast cancers (TNBCs) harbor subpopulations with BRCA1/2 mutations, hypothesized to be especially platinum-sensitive. Cancers in putative 'BRCAness' subgroups-tumors with BRCA1 methylation; low levels of BRCA1 mRNA (BRCA1 mRNA-low); or mutational signatures for HR deficiency and those with basal phenotypes-may also be sensitive to platinum...
April 30, 2018: Nature Medicine
https://www.readbyqxmd.com/read/29697781/ascending-aortic-aneurysm-repair-44-years-after-starr-edwards-caged-ball-aortic-valve-replacement
#8
Gabrielle E Hatton, Akiko Tanaka, Anthony L Estrera
We report a case of ascending aortic aneurysm repair and redo aortic valve replacement with a bioprosthesis 44 years after aortic valve replacement with a Starr-Edwards metal caged-ball prosthesis. The patient presented with a moderately stenotic caged-ball valve and a 50-mm ascending aortic aneurysm on a routine follow-up transthoracic echocardiography. We replaced the valve with a bioprosthesis at the time of aortic repair as the patient wished to stop anticoagulation therapy. Intraoperatively, we found that the cloth covering of the cage was nearly completely destroyed...
April 25, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29672423/student-evaluations-of-teachers-and-courses-time-to-wake-up-and-shake-up
#9
Kathleen M Turner, Debi Hatton, Theresa M Terry Valiga
No abstract text is available yet for this article.
May 2018: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29622942/pharmacological-agents-utilized-in-patients-with-type-2-diabetes-beyond-lowering-a1c
#10
Joanna W Chung, Melody L Hartzler, Ashley Smith, Jessica Hatton, Kristi Kelley
Staying up to date with evolving pharmacotherapies is important to providing optimal therapies to patients. The authors present available evidence to support the role of novel and existing agents in treating type-2 diabetes.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29621072/a-comprehensive-onboarding-and-orientation-plan-for-neurocritical-care-advanced-practice-providers
#11
Tamra M Langley, Jeremy Dority, Justin F Fraser, Kevin W Hatton
BACKGROUND: As the role of advanced practice providers (APPs) expands to include increasingly complex patient care within the intensive care unit, the educational needs of these providers must also be expanded. An onboarding process was designed for APPs in the neurocritical care service line. METHODS: Onboarding for new APPs revolved around 5 specific areas: candidate selection, proctor assignment, 3-phased orientation process, remediation, and mentorship. To ensure effective training for APPs, using the most time-conscious approach, the backbone of the process is a structured curriculum...
April 4, 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/29619866/enteral-guanfacine-to-treat-severe-anxiety-and-agitation-complicating-critical-care-after-cardiac-surgery
#12
Habib Srour, Komal Pandya, Alex Flannery, Kevin Hatton
This article is the first reported case describing the off-label use of enteral immediate-release guanfacine, a long-acting α-2 adrenergic agonist most commonly used in the treatment of attention-deficit hyperactivity disorder, for sedation in a patient with severe anxiety and agitation limiting mechanical ventilation weaning several days after cardiac surgery. In this case, after several days of unsuccessful attempts to control his agitation and anxiety with conventional therapies, guanfacine therapy was initiated, and the patient was rapidly weaned from all other sedatives and mechanical ventilation shortly thereafter...
April 1, 2018: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29619469/electrically-controlled-mass-transport-into-microfluidic-droplets-from-nanodroplet-carriers-with-application-in-controlled-nanoparticle-flow-synthesis
#13
Tonghan Gu, Cao Zheng, Fan He, Yunfei Zhang, Saif A Khan, T Alan Hatton
Microfluidic droplets have been applied extensively as reaction vessels in a wide variety of chemical and biological applications. Typically, once the droplets are formed in a flow channel, it is a challenge to add new chemicals to the droplets for subsequent reactions in applications involving multiple processing steps. Here, we present a novel and versatile method that employs a high strength alternating electrical field to tunably transfer chemicals into microfluidic droplets using nanodroplets as chemical carriers...
April 5, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29609076/negative-fateful-life-events-in-midlife-and-advanced-predicted-brain-aging
#14
Sean N Hatton, Carol E Franz, Jeremy A Elman, Matthew S Panizzon, Donald J Hagler, Christine Fennema-Notestine, Lisa T Eyler, Linda K McEvoy, Michael J Lyons, Anders M Dale, William S Kremen
Negative fateful life events (FLEs) such as interpersonal conflict, death in the family, financial hardship, and serious medical emergencies can act as allostatic stressors that accelerate biological aging. However, the relationship between FLEs and neuroanatomical aging is not well understood. We examined 359 men (mean age 62 years) participating in the Vietnam Era twin study of aging (VETSA) to determine whether negative midlife FLEs are associated with advanced brain aging after controlling for physical, psychological, and lifestyle factors...
March 8, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29587712/the-association-between-employment-status-and-health-among-british-adults-with-and-without-intellectual-impairments-cross-sectional-analyses-of-a-cohort-study
#15
Eric Emerson, Chris Hatton, Susannah Baines, Janet Robertson
BACKGROUND: There exists a well established link between employment status and health, with unemployment being associated with poorer health. Much less is known about the association between economic inactivity and health, especially among people with disabilities. Our aim is to determine whether the association between employment status and health is similar for adults with and adults without intellectual impairment. METHODS: Using nationally representative data from the 1970 British Cohort Study, we undertook a series of cross sectional analyses of the association between employment status and health (self-reported general health, mental health) among British adults with and without intellectual impairments at ages 26, 30, 34, 38 and 42...
March 27, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29575043/preventing-family-transmission-of-anxiety-feasibility-rct-of-a-brief-intervention-for-parents
#16
Sam Cartwright-Hatton, Donna Ewing, Suzanne Dash, Zoe Hughes, Ellen J Thompson, Cassie M Hazell, Andy P Field, Helen Startup
OBJECTIVES: Children of anxious parents are at high risk of anxiety disorders themselves. The evidence suggests that this is due to environmental rather than genetic factors. However, we currently do little to reduce this risk of transmission. There is evidence that supporting parenting in those with mental health difficulties can ameliorate this risk. Therefore, the objective of this study was to test the feasibility of a new one-session, group-based, preventive parenting intervention for parents with anxiety disorders...
March 25, 2018: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29571052/non-eluting-surface-bound-enzymes-disrupt-surface-attachment-of-bacteria-by-continuous-biofilm-polysaccharide-degradation
#17
Dalal Asker, Tarek S Awad, Perrin Baker, P Lynne Howell, Benjamin D Hatton
Bacterial colonization and biofilm formation on surfaces are typically mediated by the deposition of exopolysaccharides and conditioning protein layers. Pseudomonas aeruginosa is a nosocomial opportunistic pathogen that utilizes strain-specific exopolysaccharides such as Psl, Pel or alginate for both initial surface attachment and biofilm formation. To generate surfaces that resist P. aeruginosa colonization, we covalently bound a Psl-specific glycoside hydrolase (PslGh ) to several, chemically-distinct surfaces using amine functionalization (APTMS) and glutaraldehyde (GDA) linking...
March 14, 2018: Biomaterials
https://www.readbyqxmd.com/read/29551205/visual-fixation-and-scan-patterns-of-dentists-viewing-dental-periapical-radiographs-an-eye-tracking-pilot-study
#18
Brian P Hermanson, Grant C Burgdorf, John F Hatton, Darrin M Speegle, Karl F Woodmansey
INTRODUCTION: The visual search patterns of dentists and the areas that attract their attention when interpreting dental periapical radiographs are currently unknown. This research identifies areas and patterns of visual fixation when observing dental periapical radiographs. METHODS: In an observational study using eye tracking technology and a convenience sample of 44 observers, the interpretations of 4 dental periapical radiographs were recorded using Camtasia Software (TechSmith, Okemos, MI) with a gaze tracking "bubble" denoting where within the radiograph the observers' eyes gazed...
May 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29517988/electrospun-f18-bioactive-glass-pcl-poly-%C3%AE%C2%B5-caprolactone-membrane-for-guided-tissue-regeneration
#19
Lucas Hidalgo Pitaluga, Marina Trevelin Souza, Edgar Dutra Zanotto, Martin Eduardo Santocildes Romero, Paul V Hatton
Barrier membranes that are used for guided tissue regeneration (GTR) therapy usually lack bioactivity and the capability to promote new bone tissue formation. However, the incorporation of an osteogenic agent into polymeric membranes seems to be the most assertive strategy to enhance their regenerative potential. Here, the manufacturing of composite electrospun membranes made of poly (ε-caprolactone) (PCL) and particles of a novel bioactive glass composition (F18) is described. The membranes were mechanically and biologically tested with tensile strength tests and tissue culture with MG-63 osteoblast-like cell line, respectively...
March 8, 2018: Materials
https://www.readbyqxmd.com/read/29504207/advancing-diabetes-management-in-adolescents-comparative-effectiveness-of-mobile-self-monitoring-blood-glucose-technology-and-family-centered-goal-setting
#20
Tamara S Hannon, Lisa G Yazel-Smith, Amy S Hatton, Jennifer L Stanton, Elizabeth A S Moser, Xiaochun Li, Aaron E Carroll
BACKGROUND: As adolescents gain autonomy, it remains important for parents to be involved with diabetes management to avoid deterioration in glycemic control. Technologies for self-monitoring of blood glucose (SMBG) allow for remote monitoring in real-time by parents. This research compared 3 strategies for improving SMBG and diabetes self-care in the short-term. These strategies were: (1) health information technology (HIT)-enhanced blood glucose meter that shared blood glucose data among patients, their parent, and care providers, and allowed for text messaging; (2) family-centered goal setting; and (3) a combination of (1) and (2)...
June 2018: Pediatric Diabetes
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