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https://www.readbyqxmd.com/read/28716297/on-the-relative-merits-of-invasive-and-non-invasive-pre-surgical-brain-mapping-new-tools-in-ablative-epilepsy-surgery
#1
Andrew C Papanicolaou, Roozbeh Rezaie, Shalini Narayana, Asim F Choudhri, Abbas-Babajani-Feremi, Frederick A Boop, James W Wheless
Cortical Stimulation Mapping (CSM) and the Wada procedure have long been considered the gold standard for localizing motor and language-related cortical areas and for determining the language and memory-dominant hemisphere, respectively. In recent years, however, non-invasive methods such as magnetoencephalography (MEG), functional magnetic resonance imaging (fMRI), and transcranial magnetic stimulation (TMS) have emerged as promising alternatives to the aforementioned procedures, particularly in cases where the invasive localization of eloquent cortex has proven to be challenging...
July 3, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28708330/mortality-in-children-with-low-grade-glioma-or-glioneuronal-tumors-a-single-institution-study
#2
Santhosh A Upadhyaya, Yahya Ghazwani, Shengjie Wu, Alberto Broniscer, Fredrick A Boop, Amar Gajjar, Ibrahim Qaddoumi
BACKGROUND: While pediatric low-grade glioma/glioneuronal tumors (LGG/LGGNTs) are considered slow-growing, indolent tumors with excellent long-term prognosis, mortality due to the disease is not unknown. Few studies have addressed the cause of death in this population. METHODS: Retrospective review of clinicopathologic and radiologic data for children 21 years or younger with LGG/LGGNT who died at St. Jude Children's Research Hospital between April 1985 and June 2015...
July 14, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28686121/surgical-and-molecular-considerations-in-the-treatment-of-pediatric-thalamopeduncular-tumors
#3
Ryan P Lee, Kimberly A Foster, Jock C Lillard, Paul Klimo, David W Ellison, Brent Orr, Frederick A Boop
OBJECTIVE Thalamopeduncular tumors are a group of pediatric low-grade gliomas that arise at the interface of the thalamus and brainstem peduncle. They typically occur within the first 2 decades of life, presenting with progressive spastic hemiparesis. Treatment strategies, including surgical intervention, have varied significantly. The authors present their experience in the treatment of 13 children, ages 2-15 years, with non-neurofibromatosis-related pilocytic astrocytomas located in the thalamopeduncular region...
July 7, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28674731/tractography-guides-the-approach-for-resection-of-thalamopeduncular-tumors
#4
Ryan Foley, Frederick Boop
BACKGROUND: Thalamopeduncular tumors arise at the junction of the inferior thalamus and cerebral peduncle, and present with a common clinical syndrome of progressive spastic hemiparesis. METHOD: Formal preoperative magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) were performed. Postoperative MRI was obtained to evaluate the extent of tumor resection. A prospective analysis of clinical outcomes was then conducted by the senior author. CONCLUSIONS: Preoperative tractography is a useful adjunct to surgical planning in tumors that displace motor pathways...
July 3, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28596060/-medical-prevention-and-treatment-of-radiation-induced-pulmonary-complications
#5
A Vallard, C Rancoule, H Le Floch, J-B Guy, S Espenel, C Le Péchoux, É Deutsch, N Magné, C Chargari
Radiation-induced lung injuries mainly include the (acute or sub-acute) radiation pneumonitis, the lung fibrosis and the bronchiolitis obliterans organizing pneumonia (BOOP). The present review aims at describing the diagnostic process, the current physiopathological knowledge, and the available (non dosimetric) preventive and curative treatments. Radiation-induced lung injury is a diagnosis of exclusion, since clinical, radiological, or biological pathognomonic evidences do not exist. Investigations should necessarily include a thoracic high resolution CT-scan and lung function tests with a diffusing capacity of the lung for carbon monoxide...
June 5, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28574318/pediatric-abusive-head-trauma-and-stroke
#6
Nickalus R Khan, Brittany D Fraser, Vincent Nguyen, Kenneth Moore, Scott Boop, Brandy N Vaughn, Paul Klimo
OBJECTIVE Despite established risk factors, abusive head trauma (AHT) continues to plague our communities. Cerebrovascular accident (CVA), depicted as areas of hypodensity on CT scans or diffusion restriction on MR images, is a well-known consequence of AHT, but its etiology remains elusive. The authors hypothesize that a CVA, in isolation or in conjunction with other intracranial injuries, compounds the severity of a child's injury, which in turn leads to greater health care utilization, including surgical services, and an increased risk of death...
June 2, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28540667/neurocognitive-functioning-in-pediatric-craniopharyngioma-performance-before-treatment-with-proton-therapy
#7
Ashley S Fournier-Goodnight, Jason M Ashford, Thomas E Merchant, Frederick A Boop, Daniel J Indelicato, Lei Wang, Hui Zhang, Heather M Conklin
The goal of this study was to investigate the impact of patient-, disease-, and treatment-related variables upon neurocognitive outcomes in pediatric patients with craniopharyngioma prior to treatment with proton therapy or observation after radical resection. For all participants (N = 104), relevant clinical and demographic variables were attained and neurocognitive evaluations completed prior to irradiation or planned observation. One-sample t-tests were conducted to compare performance to published normative data...
May 24, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28532906/first-report-of-coexistence-of-two-ectopic-pituitary-tumors-rathke-cleft-cyst-and-silent-adrenocorticotropic-hormone-adenoma
#8
Mirza Pojskić, Blazej Zbytek, Neal S Beckford, Frederick A Boop, Kenan I Arnautović
BACKGROUND: Rathke cleft cysts (RCCs) and pituitary adenomas (PAs) are thought to have a common embryonic ancestry; however, PAs with a concomitant RCC inside the sella turcica are rarely observed. Ectopic pituitary tumors are also rare. CASE DESCRIPTION: We present the case of a 65-year-old woman with an ectopic RCC in the sphenoid sinus and outside the sella turcica concomitant with an adrenocorticotropic hormone (ACTH)-staining, clinically silent PA. The patient had headache but no endocrine or visual disturbances...
August 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28487419/membrane-depolarization-activates-bk-channels-through-rock-mediated-%C3%AE-1-subunit-surface-trafficking-to-limit-vasoconstriction
#9
M Dennis Leo, Xue Zhai, Padmapriya Muralidharan, Korah P Kuruvilla, Simon Bulley, Frederick A Boop, Jonathan H Jaggar
Membrane depolarization of smooth muscle cells (myocytes) in the small arteries that regulate regional organ blood flow leads to vasoconstriction. Membrane depolarization also activates large-conductance calcium (Ca(2+))-activated potassium (BK) channels, which limits Ca(2+) channel activity that promotes vasoconstriction, thus leading to vasodilation. We showed that in human and rat arterial myocytes, membrane depolarization rapidly increased the cell surface abundance of auxiliary BK β1 subunits but not that of the pore-forming BKα channels...
May 9, 2017: Science Signaling
https://www.readbyqxmd.com/read/28409726/the-suboccipital-ligament
#10
Kelsey Alabaster, M Fred Bugg, Bruno Splavski, Frederick A Boop, Kenan I Arnautovic
OBJECTIVE A fibrous structure located dorsal to the dura at the posterior craniocervical junction stretches horizontally between the bilateral occipital condyles and the upper borders of the C-1 laminae. Partially covered by the occipital bone, this structure is always encountered when the bone is removed from the foramen magnum rim during approaches to the posterior cranial fossa. Although known to surgeons, this structure has not been defined, studied, or named. The most appropriate name for this structure is "the suboccipital ligament," and a detailed rationale for this name is provided...
April 14, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28407022/gap-analysis-on-the-biology-of-mediterranean-marine-fishes
#11
Donna Dimarchopoulou, Konstantinos I Stergiou, Athanassios C Tsikliras
We estimated the current level of knowledge concerning several biological characteristics of the Mediterranean marine fishes by carrying out a gap analysis based on information extracted from the literature, aiming to identify research trends and future needs in the field of Mediterranean fish biology that can be used in stock assessments, ecosystem modeling and fisheries management. Based on the datasets that emerged from the literature review, there is no information on any biological characteristic for 43% (n = 310) of the Mediterranean fish species, whereas for an additional 15% (n = 109) of them there is information about just one characteristic...
2017: PloS One
https://www.readbyqxmd.com/read/28327927/pineoblastoma-the-experience-at-st-jude-children-s-research-hospital
#12
Kara A Parikh, Garrett T Venable, Brent A Orr, Asim F Choudhri, Frederick A Boop, Amar J Gajjar, Paul Klimo
BACKGROUND: Pineoblastomas are rare, supratentorial, primitive neuroectodermal tumors. OBJECTIVE: To document outcomes with multimodal therapy and evaluate the impact that the degree of surgical resection has on outcome. METHODS: A departmental brain tumor database was queried to identify all patients with pathologically proven pineoblastoma who were treated from January 1997 to June 2015 at St. Jude Children's Research Hospital. For each patient, we recorded demographic, pathological, radiological, surgical, and clinical follow-up data...
March 15, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28266889/lung-injury-pathways-adenosine-receptor-2b-signaling-limits-development-of-ischemic-bronchiolitis-obliterans-organizing-pneumonia
#13
John C Densmore, Terry R Schaid, Paul M Jeziorczak, Meetha Medhora, Said Audi, Shraddha Nayak, John Auchampach, Melinda R Dwinell, Aron M Geurts, Elizabeth R Jacobs
Purpose/Aim of the Study: Adenosine signaling was studied in bronchiolitis obliterans organizing pneumonia (BOOP) resulting from unilateral lung ischemia. MATERIALS AND METHODS: Ischemia was achieved by either left main pulmonary artery or complete hilar ligation. Sprague-Dawley (SD) rats, Dahl salt sensitive (SS) rats and SS mutant rat strains containing a mutation in the A2B adenosine receptor gene (Adora2b) were studied. Adenosine concentrations were measured in bronchoalveolar lavage (BAL) by HPLC...
February 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/28106480/radio-pathological-correlation-of-organizing-pneumonia-op-a-pictorial-review
#14
REVIEW
Mohammad Zare Mehrjardi, Shahram Kahkouee, Mihan Pourabdollah
Since the description of cryptogenic organizing pneumonia in 1983 by Davison et al and the subsequent report on bronchiolitis obliterans organizing pneumonia by Epler et al, some reports have been published regarding the imaging features of organizing pneumonia (OP). In this pictorial review, we aimed to describe and illustrate different manifestations of OP on high-resolution CT (HRCT) accompanied by their histopathological correlations for a better comprehension of pathomechanism of the radiological findings...
March 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28096986/extracorporeal-membrane-oxygenation-rescue-in-adolescent-with-bronchiolitis-obliterans-organizing-pneumonia-like-wegener-s-granulomatosis
#15
Lars Falk, Lars Mikael Broman
We report a 17-year-old woman with bronchiolitis obliterans-organizing pneumonia (BOOP)-like granulomatosis with polyangiitis developing severe airway obliterations. Pending age, phase and grade of autoimmune treatment, and offering ECMO treatment may be crucial for survival but occasionally preface futility. ECMO-treated patient with BOOP-like GPA has never been described before.
January 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28059677/hydrocephalus-in-a-patient-with-an-unruptured-pial-arteriovenous-fistula-hydrodynamic-considerations-endovascular-treatment-and-clinical-course
#16
Jesús A Morales-Gómez, Vicente V Garza-Oyervides, José A Arenas-Ruiz, Mariana Mercado-Flores, C Guillermo Elizondo-Riojas, Frederick A Boop, Ángel Martínez-Ponce de León
Intracranial pial arteriovenous fistulas, also known as nongalenic fistulas, are rare vascular malformations affecting predominantly the pediatric population. Hydrocephalus is an unusual presentation in which the exact pathophysiology is not fully understood. The aim of treatment in these cases is occlusion of the fistula prior to considering ventricular shunting. Here, the authors describe the hydrodynamic considerations of the paravascular pathway and the resolution of hydrocephalus with endovascular treatment of the fistula...
March 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28043704/comparative-analysis-of-selected-semi-persistent-and-emerging-pollutants-in-wild-caught-fish-and-aquaculture-associated-fish-using-bogue-boops-boops-as-sentinel-species
#17
Luis Alberto Henríquez-Hernández, Daniel Montero, María Camacho, Rafael Ginés, Luis D Boada, Besay Ramírez Bordón, Pilar F Valerón, Maira Almeida-González, Manuel Zumbado, Ricardo Haroun, Octavio P Luzardo
The marine environment acts as a sink for diverse anthropogenic pollutants, although the environmental contamination may be non-uniformly distributed. In recent decades, the aquaculture sector has experienced a steady growth postulating as a good alternative for seafood production. However, a social debate exits about the differential level of pollutants in wild and farmed species. This study was designed to evaluate the level of pollutants in a sentinel species: Bogue (Boops boops) associated and non-associated to fish-farm cages...
December 30, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/28040529/primary-seeding-of-myxopapillary-ependymoma-different-disease-in-adult-population-case-report-and-review-of-literature
#18
Nickalus R Khan, Matthew VanLandingham, Thomas O'Brien, Frederick A Boop, Kenan Arnautović
Myxopapillary ependymoma (MPE) is a slow-growing tumor, occurring most often in adults. It originates from the filum terminale in the area of the conus medullaris and cauda equina and is considered a benign lesion. Despite this classification, however, recurrence after both partial and gross total resection is well known. In the pediatric population, primary MPE seeding and generally more aggressive clinical course is well documented and treated through gross total resection, if possible, followed by irradiation...
March 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27888588/lps-responsive-beige-like-anchor-gene-mutation-associated-with-possible-bronchiolitis-obliterans-organizing-pneumonia-associated-with-hypogammaglobulinemia-and-normal-igm-phenotype-and-low-number-of-b-cells
#19
Sima Shokri, Mohammad Nabavi, Tatjana Hirschmugl, Asghar Aghamohammadi, Saba Arshi, Mohamad Hassan Bemanian, Morteza Fallahpour, Rasool Molatefi, Mahsa Rekabi, Narges Eslami, Javad Ahmadian, Kian Darabi, Gholam Reza Sedighi, Maryam Monajemzadeh, Mohammadreza Modaresi, Nima Parvaneh, Kaan Boztug, Nima Rezaei
LPS-Responsive Beige-like Anchor (LRBA) deficiency is a disease which has recently been described in a group of patients with common variable immunodeficiency (CVID) in association with autoimmunity and/or inflammatory bowel disease (IBD)-like phenotype. We here describe a 10-year-old boy who experienced recurrent infections, mainly in the respiratory system, associated with thrombocytopenia and anemia. Immunological workup showed low numbers of B cells and low IgG, but normal IgM levels. In spite of therapeutic doses of antibiotics, antivirals, and antifungal agents, in addition to immunoglobulin replacement therapy, he developed disseminated involvement of both lungs with peripheral nodules; transbronchial lung biopsy revealed possible bronchiolitis obliterans organizing pneumonia (BOOP)...
October 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27798855/retreatment-of-a-choroidal-vein-of-galen-malformation-with-embolization-42%C3%A2-years-after-open-surgical-treatment-in-the-neonatal-period
#20
Lucas Elijovich, Asim F Choudhri, Adam S Arthur, Paul Klimo, Frederick A Boop, Alejandro Berenstein
In 1976 an infant boy initially presented with a choroidal vein of Galen malformation (cVOGM). Craniotomy and clipping of the anterior cerebral artery and posterior choroidal arteries was performed, which was reported in the literature 40 years ago. The patient remained asymptomatic until age 42 when he re-presented with an isolated intraventricular hemorrhage. Angiography demonstrated cVOGM with venous sinus occlusive disease leading to venous hypertension and subsequent intraventricular hemorrhage. The angiogram also demonstrated a 'pseudo-nidus' composed of multiple arterial-to-arterial anastomoses that had developed as a result of the original surgical treatment...
May 2017: Journal of Neurointerventional Surgery
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