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https://www.readbyqxmd.com/read/28266889/lung-injury-pathways-adenosine-receptor-2b-signaling-limits-development-of-ischemic-bronchiolitis-obliterans-organizing-pneumonia
#1
John C Densmore, Terry R Schaid, Paul M Jeziorczak, Meetha Medhora, Said Audi, Shraddha Nayak, John Auchampach, Melinda R Dwinell, Aron M Geurts, Elizabeth R Jacobs
Purpose/Aim of the Study: Adenosine signaling was studied in bronchiolitis obliterans organizing pneumonia (BOOP) resulting from unilateral lung ischemia. MATERIALS AND METHODS: Ischemia was achieved by either left main pulmonary artery or complete hilar ligation. Sprague-Dawley (SD) rats, Dahl salt sensitive (SS) rats and SS mutant rat strains containing a mutation in the A2B adenosine receptor gene (Adora2b) were studied. Adenosine concentrations were measured in bronchoalveolar lavage (BAL) by HPLC...
March 7, 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/28106480/radio-pathological-correlation-of-organizing-pneumonia-op-a-pictorial-review
#2
Mohammad Zare Mehrjardi, Shahram Kahkouee, Mihan Pourabdollah
Since the description of cryptogenic organizing pneumonia in 1983 by Davison et al and the subsequent report on bronchiolitis obliterans organizing pneumonia by Epler et al, some reports have been published regarding the imaging features of organizing pneumonia (OP). In this pictorial review, we aimed to describe and illustrate different manifestations of OP on high-resolution CT (HRCT) accompanied by their histopathological correlations for a better comprehension of pathomechanism of the radiological findings...
February 17, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28096986/extracorporeal-membrane-oxygenation-rescue-in-adolescent-with-bronchiolitis-obliterans-organizing-pneumonia-like-wegener-s-granulomatosis
#3
Lars Falk, Lars Mikael Broman
We report a 17-year-old woman with bronchiolitis obliterans-organizing pneumonia (BOOP)-like granulomatosis with polyangiitis developing severe airway obliterations. Pending age, phase and grade of autoimmune treatment, and offering ECMO treatment may be crucial for survival but occasionally preface futility. ECMO-treated patient with BOOP-like GPA has never been described before.
January 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28059677/hydrocephalus-in-a-patient-with-an-unruptured-pial-arteriovenous-fistula-hydrodynamic-considerations-endovascular-treatment-and-clinical-course
#4
Jesús A Morales-Gómez, Vicente V Garza-Oyervides, José A Arenas-Ruiz, Mariana Mercado-Flores, C Guillermo Elizondo-Riojas, Frederick A Boop, Ángel Martínez-Ponce de León
Intracranial pial arteriovenous fistulas, also known as nongalenic fistulas, are rare vascular malformations affecting predominantly the pediatric population. Hydrocephalus is an unusual presentation in which the exact pathophysiology is not fully understood. The aim of treatment in these cases is occlusion of the fistula prior to considering ventricular shunting. Here, the authors describe the hydrodynamic considerations of the paravascular pathway and the resolution of hydrocephalus with endovascular treatment of the fistula...
March 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28043704/comparative-analysis-of-selected-semi-persistent-and-emerging-pollutants-in-wild-caught-fish-and-aquaculture-associated-fish-using-bogue-boops-boops-as-sentinel-species
#5
Luis Alberto Henríquez-Hernández, Daniel Montero, María Camacho, Rafael Ginés, Luis D Boada, Besay Ramírez Bordón, Pilar F Valerón, Maira Almeida-González, Manuel Zumbado, Ricardo Haroun, Octavio P Luzardo
The marine environment acts as a sink for diverse anthropogenic pollutants, although the environmental contamination may be non-uniformly distributed. In recent decades, the aquaculture sector has experienced a steady growth postulating as a good alternative for seafood production. However, a social debate exits about the differential level of pollutants in wild and farmed species. This study was designed to evaluate the level of pollutants in a sentinel species: Bogue (Boops boops) associated and non-associated to fish-farm cages...
December 30, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/28040529/primary-seeding-of-myxopapillary-ependymoma-different-disease-in-adult-population-case-report-and-review-of-literature
#6
Nickalus R Khan, Matthew VanLandingham, Thomas O'Brien, Frederick A Boop, Kenan Arnautović
Myxopapillary ependymoma (MPE) is a slow-growing tumor, occurring most often in adults. It originates from the filum terminale in the area of the conus medullaris and cauda equina and is considered a benign lesion. Despite this classification, however, recurrence after both partial and gross total resection is well known. In the pediatric population, primary MPE seeding and generally more aggressive clinical course is well documented and treated through gross total resection, if possible, followed by irradiation...
March 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27888588/lps-responsive-beige-like-anchor-gene-mutation-associated-with-possible-bronchiolitis-obliterans-organizing-pneumonia-associated-with-hypogammaglobulinemia-and-normal-igm-phenotype-and-low-number-of-b-cells
#7
Sima Shokri, Mohammad Nabavi, Tatjana Hirschmugl, Asghar Aghamohammadi, Saba Arshi, Mohamad Hassan Bemanian, Morteza Fallahpour, Rasool Molatefi, Mahsa Rekabi, Narges Eslami, Javad Ahmadian, Kian Darabi, Gholam Reza Sedighi, Maryam Monajemzadeh, Mohammadreza Modaresi, Nima Parvaneh, Kaan Boztug, Nima Rezaei
LPS-Responsive Beige-like Anchor (LRBA) deficiency is a disease which has recently been described in a group of patients with common variable immunodeficiency (CVID) in association with autoimmunity and/or inflammatory bowel disease (IBD)-like phenotype. We here describe a 10-year-old boy who experienced recurrent infections, mainly in the respiratory system, associated with thrombocytopenia and anemia. Immunological workup showed low numbers of B cells and low IgG, but normal IgM levels. In spite of therapeutic doses of antibiotics, antivirals, and antifungal agents, in addition to immunoglobulin replacement therapy, he developed disseminated involvement of both lungs with peripheral nodules; transbronchial lung biopsy revealed possible bronchiolitis obliterans organizing pneumonia (BOOP)...
October 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27798855/retreatment-of-a-choroidal-vein-of-galen-malformation-with-embolization-42%C3%A2-years-after-open-surgical-treatment-in-the-neonatal-period
#8
Lucas Elijovich, Asim F Choudhri, Adam S Arthur, Paul Klimo, Frederick A Boop, Alejandro Berenstein
In 1976 an infant boy initially presented with a choroidal vein of Galen malformation (cVOGM). Craniotomy and clipping of the anterior cerebral artery and posterior choroidal arteries was performed, which was reported in the literature 40 years ago. The patient remained asymptomatic until age 42 when he re-presented with an isolated intraventricular hemorrhage. Angiography demonstrated cVOGM with venous sinus occlusive disease leading to venous hypertension and subsequent intraventricular hemorrhage. The angiogram also demonstrated a 'pseudo-nidus' composed of multiple arterial-to-arterial anastomoses that had developed as a result of the original surgical treatment...
October 8, 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27773422/clinical-characteristics-and-long-term-outcomes-of-movement-disorders-in-childhood-thalamic-tumors
#9
Zsila S Sadighi, Jennifer Zabrowski, Frederick A Boop, Alberto Broniscer, Amar Gajjar, Raja B Khan
BACKGROUND: We studied the outcomes of movement disorders that were associated with childhood thalamic tumors. METHODS: We retrospectively reviewed 83 children with thalamic tumors treated at our institution from 1996 to 2013 to document the incidence and outcome of movement disorders. Magnetic resonance imaging was used to analyze the involvement of thalamic nuclei, and three instruments were used to rate the severity of the disorders. RESULTS: Nine (11%) patients had one or more of the following movement disorders: postural tremor, resting tremor, ballism, dystonia, myoclonus, and athetosis...
December 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/27705947/mirna203-suppresses-the-expression-of-protumorigenic-stat1-in-glioblastoma-to-inhibit-tumorigenesis
#10
Chuan He Yang, Yinan Wang, Michelle Sims, Chun Cai, Ping He, Junming Yue, Jinjun Cheng, Frederick A Boop, Susan R Pfeffer, Lawrence M Pfeffer
MicroRNAs (miRNAs) play critical roles in regulating cancer cell proliferation, migration, survival and sensitivity to chemotherapy. The potential application of using miRNAs for cancer prognosis holds great promise but miRNAs with predictive value remain to be identified and underlying mechanisms of how they promote or suppress tumorigenesis are not completely understood. Here, we show a strong correlation between miR203 expression and brain cancer patient survival. Low miR203 expression is found in subsets of brain cancer patients, especially glioblastoma...
December 20, 2016: Oncotarget
https://www.readbyqxmd.com/read/27702926/retreatment-of-a-choroidal-vein-of-galen-malformation-with-embolization-42%C3%A2-years-after-open-surgical-treatment-in-the-neonatal-period
#11
Lucas Elijovich, Asim F Choudhri, Adam S Arthur, Paul Klimo, Frederick A Boop, Alejandro Berenstein
In 1976 an infant boy initially presented with a choroidal vein of Galen malformation (cVOGM). Craniotomy and clipping of the anterior cerebral artery and posterior choroidal arteries was performed, which was reported in the literature 40 years ago. The patient remained asymptomatic until age 42 when he re-presented with an isolated intraventricular hemorrhage. Angiography demonstrated cVOGM with venous sinus occlusive disease leading to venous hypertension and subsequent intraventricular hemorrhage. The angiogram also demonstrated a 'pseudo-nidus' composed of multiple arterial-to-arterial anastomoses that had developed as a result of the original surgical treatment...
October 4, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27659834/epilepsy-surgery-for-pediatric-low-grade-gliomas-of-the-cerebral-hemispheres-neurosurgical-considerations-and-outcomes
#12
REVIEW
Matthew T Brown, Frederick A Boop
INTRODUCTION: Pediatric low-grade tumors are found in roughly 1-3 % of patients with childhood epilepsy; seizures associated with these tumors are often medically refractory and often present a significant morbidity, greater than the presence of the tumor itself. DISCUSSION: The unique morbidity of the seizures often requires an epilepsy surgical approach over a standard oncologic resection to achieve a reduction in morbidity for the child. Multiple quality-of-life studies have shown that unless a patient is seizure-free, they remain disabled throughout their life; the best way to achieve this in our patient population is with a multidisciplinary team approach with treatment goals focusing primarily on the epilepsy...
October 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27595482/melanotic-neuroectodermal-tumor-of-infancy-with-involvement-of-the-superior-sagittal-sinus
#13
Kimberly A Foster, Asim Choudhri, Ryan Lingo, Frederick Boop
Melanotic neuroectodermal tumor of infancy (MNTI) is a rare lesion that typically manifests in the first year of life, most commonly involving the facial bones. We present 2 infants with MNTI involving the posterior skull with associated compression of the superior sagittal sinus (SSS). A review of the anatomical locations of MNTI is offered, and the implications of SSS involvement are described. This represents the first known description of MNTI with involvement of the posterior SSS.
2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27451594/haemoptysis-as-a-primary-manifestation-of-cryptogenic-organizing-pneumonia-cop
#14
Fotini Chatzivasiloglou, Stamatis Katsenos, Konstantinos Psathakis, Konstantinos Tsintiris
Cryptogenic organizing pneumonia (COP), previously called bronchiolitis obliterans organizing pneumonia (BOOP) is a clinicopathological disorder of unknown aetiology but increasingly reported. It usually presents with symptoms of dyspnea, cough, fever, weight loss accompanied by the presence of alveolar opacities on chest radiograph. Haemoptysis, described as blood streaking has only rarely been reported as primary presentation of COP. Herein, we report a case of COP in which submassive haemoptysis was the main clinical manifestation...
October 2015: Pneumologia: Revista Societății Române de Pneumologie
https://www.readbyqxmd.com/read/27412744/-bronchitis-obliterans-associated-with-bronchiolitis-obliterans-with-organizing-pneumonia-in-a-child-and-literature-review
#15
REVIEW
Q Han, Y Shi, H X Li, W W Tang, H X Liu, D Y Zhao
OBJECTIVE: To investigate the clinical-radiologic-pathologic features of bronchitis obliterans that complicated with bronchiolitis obliterans with organizing pneumonia (BOOP). METHOD: The clinical manifestations, characteristic imaging and pathology of a case with pediatric Mycoplasma pneumoniae pneumonia (MPP) complicated with bronchitis obliterans and BOOP were summarized and relative articles were reviewed. RESULT: A 10-year-old girl complained of recurrent paroxysmal cough and episodes of wheezing with exercise, productive of yellowish sputum, irregular fever for 1 month presented with lower breath sounds of left lower lobe and localized tubular breath sounds...
July 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27408784/bronchiolitis-obliterans-organizing-pneumonia-associated-with-achalasia-a-case-report
#16
Farhad Malek, Hossein Nobakhat, Hamidreza Hemmati
There is little mention in the literature about achalasia as an etiologic factor of Bronchiolitis obliterans organizing pneumonia (BOOP). In this study, a case of BOOP, which appeared to be secondary to achalasia is reported. A 35 years old man present with nonproductive cough, chills and fever from two month ago. Due to permanent consolidation in mid zone of right lung and unresponsive to antibiotics, transthoracic needle biopsy was done that showed BOOP. Due to esophageal dilatation in chest computerized tomography (CT) scan, endoscopy and esophagogram was done that showed achalasia...
2016: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27402215/abusive-head-trauma-an-epidemiological-and-cost-analysis
#17
Scott Boop, Mary Axente, Blakely Weatherford, Paul Klimo
OBJECTIVE Research on pediatric abusive head trauma (AHT) has largely focused on clinical presentation and management. The authors sought to review a single-institution experience from a public health perspective to gain a better understanding of the local population affected, determine overall incidence and seasonal trends, and provide details on the initial hospitalization, including extent of injuries, neurosurgical interventions, and hospital charges. METHODS All cases of AHT involving patients who presented to Le Bonheur Children's Hospital (LBCH) from 2009 through 2014 were identified...
November 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27200095/bronchiolitis-obliterans-organizing-pneumonia-as-an-initial-presentation-of-systemic-lupus-erythematosus-a-rare-case-report-and-literature-review
#18
Hung-Ping Wang, Chun-Ming Chen, Yih-Yuan Chen, Wei Chen
The etiology of bronchiolitis obliterans organizing pneumonia (BOOP) remains controversial. While it has been reportedly associated with several connective tissue disorders, there are only rare reports of BOOP associated with systemic lupus erythematosus (SLE). Herein, we report a 56-year-old female patient who presented with dyspnea on exertion, cough, fever, and joint pain of her left wrist and fingers as initial symptoms. Laboratory tests revealed positivity for anti-nuclear antibody, anti-Ro, and anti-double strand DNA antibody...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27131810/high-levels-of-microplastic-ingestion-by-the-semipelagic-fish-bogue-boops-boops-l-around-the-balearic-islands
#19
M A Nadal, C Alomar, S Deudero
For the first time this study reports on the presence of microplastics (1 nm to <5 mm) in the gastrointestinal tracts of small semipelagic fish (Boops boops) in the Balearic Islands (Mediterranean Sea) from March to May 2014. The results show microplastic ingestion in 68% of full stomach samples with an average of 3.75 items per fish. Only filament type microplastics were observed in B. boops full gastrointestinal tracts. The frequency of occurrence of microplastics was high, with values ranging from 42% to 80%, in comparison to the other ingested items...
July 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27117266/quantitative-imaging-analysis-of-posterior-fossa-ependymoma-location-in-children
#20
Noah D Sabin, Thomas E Merchant, Xingyu Li, Yimei Li, Paul Klimo, Frederick A Boop, David W Ellison, Robert J Ogg
PURPOSE: Imaging descriptions of posterior fossa ependymoma in children have focused on magnetic resonance imaging (MRI) signal and local anatomic relationships with imaging location only recently used to classify these neoplasms. We developed a quantitative method for analyzing the location of ependymoma in the posterior fossa, tested its effectiveness in distinguishing groups of tumors, and examined potential associations of distinct tumor groups with treatment and prognostic factors...
August 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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