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https://www.readbyqxmd.com/read/28095705/what-s-the-story-a-computational-analysis-of-narrative-competence-in-autism
#1
Michelle Lee, Gary E Martin, Abigail Hogan, Deanna Hano, Peter C Gordon, Molly Losh
Individuals with autism spectrum disorder demonstrate narrative (i.e. storytelling) difficulties which can significantly impact their ability to form and maintain social relationships. However, existing research has not comprehensively documented these impairments in more open-ended, emotionally evocative situations common to daily interactions. Computational linguistic measures offer a promising complement to traditional hand-coding methods of narrative analysis and in this study were applied together with hand coding of narratives elicited with emotionally salient scenes from the Thematic Apperception Test...
January 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28081585/drug-eluting-stent-placement-versus-coronary-artery-bypass-surgery-for-unprotected-left-main-coronary-artery-disease-a-meta-analysis-of-randomized-controlled-trials
#2
Sunil Upadhaya, Ramkaji Baniya, Seetharamprasad Madala, Suresh Kumar Subedi, Jahangir Khan, Ravi Kanth Velagapudi, Ghassan Bachuwa
BACKGROUND: Coronary artery bypass grafting (CABG) is the standard of care for treating left main coronary lesions. However, recently published randomized controlled trials (RCT) have shown conflicting results. We sought to compare clinical outcomes of percutaneous coronary intervention (PCI) with drug-eluting stent placement to CABG using a meta-analysis of randomized controlled trials. METHODS: A systemic search of Pubmed, Scopus, Cochrane library, and Clinicaltrials...
January 12, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28078554/syntax-response-space-biases-for-hands-not-feet
#3
Timothy W Boiteau, Cameron Smith, Amit Almor
A number of studies have shown a relationship between comprehending transitive sentences and spatial processing (e.g., Chatterjee, Trends in Cognitive Sciences, 5(2), 55-61, 2001), in which there is an advantage for responding to images that depict the agent of an action to the left of the patient. Boiteau and Almor (Cognitive Science, 2016) demonstrated that a similar effect is found for pure linguistic information, such that after reading a sentence, identifying a word that had appeared earlier as the agent is faster on the left than on the right, but only for left-hand responses...
January 11, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28063244/single-sided-deafness-affects-language-and-auditory-development-a-case-control-study
#4
Anouk Sangen, Liesbeth Royackers, Christian Desloovere, Jan Wouters, Astrid van Wieringen
OBJECTIVES: To examine auditory, linguistic and cognitive outcomes of children with single sided deafness (SSD). An increasing body of research suggests that children with SSD lag behind with respect to their normal hearing (NH) peers. In the present study we tap into certain developmental skills. DESIGN: Case-control study. PARTICIPANTS: 21 children with SSD between 5 and 15 years of age participated. Per child with SSD two NH control children were matched on age and gender...
January 7, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28056847/impact-of-diabetes-and-hypertension-on-cardiovascular-outcomes-in-patients-with-coronary-artery-disease-receiving-percutaneous-coronary-intervention
#5
Mao-Jen Lin, Chun-Yu Chen, Hau-De Lin, Han-Ping Wu
BACKGROUND: Percutaneous coronary intervention (PCI) is a necessary procedure commonly performed for patients with coronary artery disease (CAD). However, the impact of diabetes and hypertension on long-term outcomes of patients after receiving PCI has not yet been determined. METHODS: The data of 1234 patients who received PCI were collected prospectively, and patients were divided into four groups, including patients with and without DM and those with either DM or hypertension alone...
January 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28053117/gb3-0-a-platform-for-plant-bio-design-that-connects-functional-dna-elements-with-associated-biological-data
#6
Marta Vazquez-Vilar, Alfredo Quijano-Rubio, Asun Fernandez-Del-Carmen, Alejandro Sarrion-Perdigones, Rocio Ochoa-Fernandez, Peio Ziarsolo, José Blanca, Antonio Granell, Diego Orzaez
Modular DNA assembly simplifies multigene engineering in Plant Synthetic Biology. Furthermore, the recent adoption of a common syntax to facilitate the exchange of plant DNA parts (phytobricks) is a promising strategy to speed up genetic engineering. Following this lead, here, we present a platform for plant biodesign that incorporates functional descriptions of phytobricks obtained under pre-defined experimental conditions, and systematically registers the resulting information as metadata for documentation...
January 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28045102/peripheral-blood-circular-rna-hsa_circ_0124644-can-be-used-as-a-diagnostic-biomarker-of-coronary-artery-disease
#7
Zhenzhou Zhao, Xuejie Li, Chuanyu Gao, Dongdong Jian, Peiyuan Hao, Lixin Rao, Muwei Li
The aim of the present study was to investigate the expression of circular RNAs (circRNAs) in the peripheral blood of coronary artery disease (CAD) patients and the potential use of circRNAs as diagnostic biomarkers of CAD. We first analysed peripheral blood circRNAs of 12 CAD patients and 12 control individuals by RNA microarray and found that 22 circRNAs were differentially expressed between these two groups: 12 were upregulated, and 10 were downregulated. Then, we selected 5 circRNAs as candidate biomarkers under stricter screening criteria and verified them in another group of subjects consisting of 30 control individuals and 30 CAD patients with different SYNTAX scores...
January 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28041714/comparison-of-prognostic-risk-scores-after-successful-primary-percutaneous-coronary-intervention
#8
Andreas Synetos, George Georgiopoulos, Voula Pylarinou, Konstantinos Toutouzas, Katerina Maniou, Maria Drakopoulou, Panagiotis Tolis, Antonios Karanasos, Aggelos Papanikolaou, George Latsios, Eleftherios Tsiamis, Dimitrios Tousoulis
BACKGROUND: The aim of this study was to compare the predictive ability of clinical risk scores (ACEF, EuroSCORE and EuroSCORE II) to angiographic (SYNTAX score) and combined risk scores (Global Risk Score and Clinical SXscore) towards cardiovascular death and/or major adverse cardiac events (MACE) in patients with ST-segment elevation acute myocardial infarction (STEMI) managed with primary percutaneous coronary intervention (pPCI). METHODS: A total of 685 patients successfully treated with pPCI were evaluated and the risk scores were calculated...
December 24, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28038806/bioresorbable-coronary-stent-for-the-treatment-of-complex-coronary-lesions-data-from-an-all-comer-registry
#9
Andrea Cuculo, Antonio Ruggiero, Antonio Centola, Giulio Campanale, Tommaso Passero, Antonio Gaglione, Matteo Di Biase, Natale Daniele Brunetti
BACKGROUND: The study aimed to report the results from an all-comers registry of patients undergoing coronary angioplasty and treated with bioresorbable vascular scaffold (BVS). METHODS: Fifty-five consecutive patients with type B/C coronary lesions according to the AHA classification and treated with BVS were enrolled in the study. The clinical and procedural characteristics of enrolled patients were recorded. Fifty-five consecutive subjects with coronary lesions type B/C treated with everolimus eluting stent (EES) were used as control group...
December 19, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28029362/impact-of-multivessel-coronary-artery-disease-with-versus-without-left-main-coronary-artery-disease-on-long-term-mortality-after-coronary-bypass-grafting-versus-drug-eluting-stent-implantation
#10
Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W Serruys, Seung-Jung Park
Limited data are available on the impact of concomitant left main coronary artery disease (CAD) on mortality after revascularization of multivessel coronary artery disease (MVD) alone or multivessel plus left main coronary artery disease (MVLMD). This study compared long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) with drug-eluting stents in 2,887 patients with MVD or MVLMD. Data were pooled from the BEST, PRECOMBAT, and SYNTAX trials. The primary outcome was death due to any cause...
October 8, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28028450/syntax-score-in-patients-with-high-computed-tomography-coronary-calcium-score
#11
Madhav Hegde, Ravindran Rajendran
OBJECTIVES: To study the conventional coronary angiogram ( CA) findings in patients with high coronary calcium on multidetector computed tomogram. MATERIALS AND METHODS: Fifty patients with coronary calcium high enough in its extent and location to interfere with the interpretation of a contrast-filled coronary artery for a significant lesion were studied with conventional CA. Framingham risk score (FRS), computed tomography (CT) coronary calcium score (CCS), and SYNTAX score (SS) from the CA were calculated by separate investigators who were blinded to other scores...
2016: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28007880/residual-syntax-score-following-coronary-artery-bypass-grafting%C3%A2
#12
Giovanni Melina, Emiliano Angeloni, Simone Refice, Cristian Benegiamo, Andrea Lechiancole, Maria Matteucci, Antonino Roscitano, Roberto Bianchini, Fabio Capuano, Cosimo Comito, Pietro Spitaleri, Euclide Tonelli, Giulio Speciale, Christian Pristipino, Francesco Monti, Roberto Serdoz, Francesco Paneni, Riccardo Sinatra
OBJECTIVES: To quantify residual coronary artery disease measured using the SYNTAX score (SS) and its relation to outcomes after coronary artery bypass grafting (CABG). METHODS: We conducted a retrospective analysis on a consecutive series of 1608 patients [mean age 68 years, standard deviation (SD): 7, F:M, 242:1366] undergoing first-time isolated CABG from 2004 to 2015. The baseline SS was retrospectively determined from preoperative angiograms, and the residual SS (rSS) was measured during assessment of the actual operative report for each patient after CABG...
December 22, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28007494/built-environmental-factors-and-adults-travel-behaviors-role-of-street-layout-and-local-destinations
#13
Mohammad Javad Koohsari, Neville Owen, Rachel Cole, Suzanne Mavoa, Koichiro Oka, Tomoya Hanibuchi, Takemi Sugiyama
Street layout is consistently associated with adults' travel behaviors, however factors influencing this association are unclear. We examined associations of street layout with travel behaviors: walking for transport (WT) and car use; and, the extent to which these relationships may be accounted for by availability of local destinations. A 24-h travel diary was completed in 2009 by 16,345 adult participants of the South-East Queensland Household Travel Survey, Australia. Three travel-behavior outcomes were derived: any home-based WT; over 30min of home-based WT; and, over 60min of car use...
December 19, 2016: Preventive Medicine
https://www.readbyqxmd.com/read/28007201/incidence-characteristics-predictors-and%C3%A2-outcomes-of-repeat-revascularization-after-percutaneous-coronary-intervention-and-coronary-artery-bypass-grafting-the-syntax-trial-at-5-years
#14
Catalina A Parasca, Stuart J Head, Milan Milojevic, Michael J Mack, Patrick W Serruys, Marie-Claude Morice, Friedrich W Mohr, Ted E Feldman, Antonio Colombo, Keith D Dawkins, David R Holmes, Pieter A Kappetein
OBJECTIVES: The study sought to determine the incidence, predictors, characteristics, and outcomes of repeat revascularization during 5-year follow-up of the SYNTAX (Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery) trial. BACKGROUND: Limited in-depth long-term data on repeat revascularization are available from randomized trials comparing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). METHODS: Incidence and timing of repeat revascularization and its relation to the long-term composite safety endpoint of death, stroke, and myocardial infarction were analyzed in the SYNTAX trial (n = 1,800) using Kaplan-Meier analysis...
December 26, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28007199/coronary-artery-bypass-surgery-versus%C3%A2-drug-eluting-stent-implantation-for%C3%A2-left%C3%A2-main-or-multivessel-coronary-artery%C3%A2-disease-a-meta-analysis-of-individual-patient-data
#15
Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Pannipa Suwannasom, Erhan Tenekecioglu, Sung-Cheol Yun, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W Serruys, Seung-Jung Park
OBJECTIVES: The authors undertook a patient-level meta-analysis to compare long-term outcomes after coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in 3,280 patients with left main or multivessel coronary artery disease (CAD). BACKGROUND: The relative efficacy and safety of CABG versus PCI with DES for left main or multivessel CAD remain controversial. METHODS: Data were pooled from the BEST (Randomized Comparison of Coronary Artery Bypass Surgery and Everolimus Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease), PRECOMBAT (Premier of Randomized Comparison of Bypass Surgery vs...
December 26, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27995343/pre-procedural-renal-resistive-index-accurately-predicts-contrast-induced-acute-kidney-injury-in-patients-with-preserved-renal-function-submitted-to-coronary-angiography
#16
Maciej T Wybraniec, Maria Bożentowicz-Wikarek, Jerzy Chudek, Katarzyna Mizia-Stec
The study aimed to evaluate the clinical utility of ultrasonographic intra-renal blood flow parameters, together with the wide range of different risk factors, for the prediction of contrast-induced acute kidney injury (CI-AKI) in patients with preserved renal function, referred for coronary angiography or percutaneous coronary interventions (CA/PCI). This prospective study covered 95 consecutive patients (69.5% men; median age 65 years) subject to elective or urgent CA/PCI. Data regarding 128 peri-procedural variables were collected...
December 19, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27981855/individual-differences-in-language-and-working-memory-affect-children-s-speech-recognition-in-noise
#17
Ryan W McCreery, Meredith Spratford, Benjamin Kirby, Marc Brennan
OBJECTIVE: We examined how cognitive and linguistic skills affect speech recognition in noise for children with normal hearing. Children with better working memory and language abilities were expected to have better speech recognition in noise than peers with poorer skills in these domains. DESIGN: As part of a prospective, cross-sectional study, children with normal hearing completed speech recognition in noise for three types of stimuli: (1) monosyllabic words, (2) syntactically correct but semantically anomalous sentences and (3) semantically and syntactically anomalous word sequences...
December 16, 2016: International Journal of Audiology
https://www.readbyqxmd.com/read/27974670/the-syntax-score-does-not-predict-risk-of-adverse-events-in-patients-with-non-st-elevation-acute-coronary-syndrome-who-undergo-coronary-artery-bypass-graft-surgery
#18
Björn Redfors, Chun-Hui He, Tullio Palmerini, Adriano Caixeta, Gennaro Giustino, Girma Minalu Ayele, Ajay J Kirtane, Roxana Mehran, Gregg W Stone, Philippe Généreux
OBJECTIVES: We tested the ability of the SYNTAX score (SS) to predict 1-year adverse outcomes for patients with non-ST segment elevation acute coronary syndromes (NSTE-ACS) who undergo coronary artery bypass graft (CABG) surgery. BACKGROUND: The SS effectively risk stratifies patients who undergo percutaneous coronary intervention, but not patients with stable coronary disease who undergo CABG. METHODS: We calculated the SS for 457 patients with NSTE-ACS in the angiographic substudy of the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) trial who underwent CABG...
December 15, 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27973643/syntactic-versus-memory-accounts-of-the-sentence-comprehension-deficits-of-specific-language-impairment-looking-back-looking-ahead
#19
James W Montgomery, Ronald B Gillam, Julia L Evans
Purpose: Compared with same-age typically developing peers, school-age children with specific language impairment (SLI) exhibit significant deficits in spoken sentence comprehension. They also demonstrate a range of memory limitations. Whether these 2 deficit areas are related is unclear. The present review article aims to (a) review 2 main theoretical accounts of SLI sentence comprehension and various studies supporting each and (b) offer a new, broader, more integrated memory-based framework to guide future SLI research, as we believe the available evidence favors a memory-based perspective of SLI comprehension limitations...
December 1, 2016: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/27973335/non-invasive-heart-team-assessment-of-multivessel-coronary-disease-with-coronary-computed-tomography-angiography-based-on-syntax-score-ii-treatment-recommendations-design-and-rationale-of-the-randomized-syntax-iii-revolution-trial
#20
Rafael Cavalcante, Yoshinobu Onuma, Yohei Sotomi, Carlos Collet, Brian Thomsen, Campbell Rogers, Yaping Zeng, Erhan Tenekecioglu, Taku Asano, Yosuke Miyasaki, Mohammad Abdelghani, Marie-Angèle Morel, Patrick W Serruys
AIMS: To investigate whether a heart-team decision-making process regarding the choice of revascularization strategy based on non-invasive coronary multislice computed tomography angiography (MSCT) assessment of coronary artery disease (CAD) is equivalent to the standard-of-care invasive angiography based assessment in patients with multivessel CAD. METHODS AND RESULTS: The SYNTAX III Revolution trial is a prospective, multicenter, all-comers randomized trial that will randomize two Heart-Teams to select between surgical or percutaneous treatment according to either an invasive conventional angiography or a non-invasive MSCT angiography assessment in patients with multivessel CAD...
December 15, 2016: EuroIntervention
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