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https://www.readbyqxmd.com/read/29217924/types-of-cancers-diagnosed-and-the-preference-of-families-of-adult-patients-with-cancer-about-disclosing-diagnosis-to-the-patients
#1
Engida Abebe, Hana Abebe
Background: Cancer has become one of the top causes of death in developing nations killing more people than the common infectious diseases do. For several reasons, disclosing cancer diagnosis to the patient is a challenging job for physicians and family members. Materials and Methods: A cross-sectional study was done to determine the common cancer diagnosis and the preference about disclosing cancer diagnosis to the patients among attendants of adult cancer patients seen at the regular surgical OPD of St...
May 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29217733/sex-as-a-biological-variable-in-preclinical-imaging-research-initial-observations-with-18f-fluorothymidine
#2
Szeman Ruby Chan, Kelley Salem, Justin Jeffery, Ginny L Powers, Yongjun Yan, Kooresh I Shoghi, Aparna M Mahajan, Amy M Fowler
The study objective was to investigate whether sex influences 3'-deoxy-3'-[18F]fluorothymidine (18F-FLT) uptake and tissue distribution in mouse models of cancer. Methods:18F-FLT biodistribution was measured in three strains of male and female mice (129S6/SvEv, athymic nude, and BALB/c). 18F-Fluoro-2-deoxy-2-D-glucose (18F-FDG) biodistribution was performed for comparison. 18F-FLT uptake was also measured in female 129S6/SvEv mice bearing estrogen-dependent SSM3 mouse mammary tumors, male athymic nude mice bearing androgen-dependent CWR22 prostate cancer xenografts, and male and female athymic nude mice bearing estrogen-independent MDA-MB-231 human breast cancer xenografts...
December 7, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29217211/mediating-effects-of-cancer-risk-factors-on-the-association-between-race-and-cancer-incidence-analysis-of-the-nih-aarp-diet-and-health-study
#3
Tomi Akinyemiju, Justin Xavier Moore, Maria Pisu
PURPOSE: Racial disparities exist in the prevalence of cancer-related risk factors and incidence of cancer. The objective of this study is to determine if cancer-related risk factors mediate the association between race and cancer incidence. METHODS: We performed prospective analysis of data from the National Institutes of Health-American Association of Retired Persons Diet and Health Study, years 1995 through 2011. We compared differences in baseline characteristics between black and white participants using χ2 tests and Wilcoxon tests, as appropriate...
November 23, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29204896/a-comparison-of-tumour-size-measurements-with-palpation-ultrasound-and-mammography-in-male-breast-cancer-first-results-of-the-prospective-register-study
#4
Martin Streng, Atanas Ignatov, Mattea Reinisch, Serban-Dan Costa, Holm Eggemann
PURPOSE: Precise presurgical diagnosis of tumour size is essential for adequate treatment of male breast cancer (MBC). This study is aimed to compare the accuracy of clinical measurement (CE), ultrasound (US) and mammography (MG) for preoperative estimation of tumour size. METHODS: This study was conducted as a prospective, multicentre register study. One hundred and twenty-nine male patients with invasive breast cancer were included. CE, US and MG were performed in 107, 110 and 75 patients, respectively, and the estimated tumour size was compared with the histopathological (HP) tumour size...
December 4, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29204340/evaluation-of-coexistence-of-cancer-and-active-tuberculosis-16-case-series
#5
Beyhan Çakar, Aydın Çiledağ
Introduction: Tuberculosis is an important risk factor for cancer. Pulmonary TB and lung cancer(LC) may mimic each other especially in the aspect of the clinical and radiological features. The aim of the study was to evaluate the features and risk factors of cases with coexistence cancer and active TB. Methodology: We retrospectively reviewed the medical records of patients with coexisting TB and cancer a period from 2009 to 2014. We evaluated demographic data, the ways diagnosis of TB cases, the location of TB and cancer, TB treatment results of the cases...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29203614/copy-number-profiling-of-oncogenes-in-ductal-carcinoma-in-situ-of-the-male-breast
#6
Marijn Annette Vermeulen, Shusma Doebar, Carolien van Deurzen, John Martens, Paul J van Diest, Cathy B Moelans
Characterizing male breast cancer (BC) and unraveling male breast carcinogenesis is challenging because of the rarity of this disease. We investigated copy number status of 22 BC related genes in 18 cases of pure ductal carcinoma in situ (DCIS) and in 49 cases of invasive carcinoma (IC) with adjacent DCIS (DCIS-AIC) in males using multiplex ligation-dependent probe amplification (MLPA). Results were compared to female BC and correlated with survival. Overall, copy number ratio and aberration frequency including all 22 genes showed no significant difference between the 3 groups...
December 4, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/29202657/a-case-of-gastric-cancer-metastasis-to-the-breast-in-a-female-with-brca2-germline-mutation-and-literature-review
#7
Audrius Dulskas, Mahdi Al Bandar, Yoon Young Choi, Su-Jin Shin, Seung-Hoon Beom, Taeil Son, Hyung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Sung Hoon Noh
INTRODUCTION: Gastric cancer is a deadly disease. Common sites of distant metastasis of gastric cancer are the peritoneum, liver, lymph nodes, and lung. The breast is a rare site of metastasis in gastric cancer which occurs in males dominantly. PATIENTS AND METHODS: Here, we report the first case of metastatic gastric cancer to the breast in a patient with the breast cancer 2 (BRCA2) germline mutation. A 34-year-old female was admitted to the hospital with dyspepsia and a palpable mass in the left breast...
December 5, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29192217/decreased-mirna-expression-in-klinefelter-syndrome
#8
Laura Cimino, Michele Salemi, Rossella Cannarella, Rosita A Condorelli, Giorgio Giurato, Giovanna Marchese, Sandro La Vignera, Aldo E Calogero
The widelyvariable phenotypic spectrum and the different severity of symptoms in men with Klinefelter syndrome (KS) suggest a role for epigenetic mediators. Therefore, the aim of this study is to evaluate the possible involvement of miRNAs in the clinical manifestations of KS. To accomplish this, we performed a transcriptome analysis in peripheral blood mononuclear cells (PBMCs) of 10 non-mosaic KS patients, 10 aged-matched healthy men and 10 aged-matched healthy female controls with normal karyotype. After RNA extraction from PBMC and the preparation of RNA libraries, the samples were sequenced using next generation high-throughput sequencing technology...
November 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29190774/activation-of-the-cholinergic-anti-inflammatory-pathway-by-gts-21-attenuates-cisplatin-induced-acute-kidney-injury-in-mice
#9
Prodyot K Chatterjee, Michael M Yeboah, Malvika H Solanki, Gopal Kumar, Xiangying Xue, Valentin A Pavlov, Yousef Al-Abed, Christine N Metz
Acute kidney injury (AKI) is the most common side effect of cisplatin, a widely used chemotherapy drug. Although AKI occurs in up to one third of cancer patients receiving cisplatin, effective renal protective strategies are lacking. Cisplatin targets renal proximal tubular epithelial cells leading to inflammation, reactive oxygen species, tubular cell injury, and eventually cell death. The cholinergic anti-inflammatory pathway is a vagus nerve-mediated reflex that suppresses inflammation via α7 nicotinic acetylcholine receptors (α7nAChRs)...
2017: PloS One
https://www.readbyqxmd.com/read/29189374/metastatic-male-breast-cancer-with-increased-uptake-on-18f-fluciclovine-pet-ct-scan
#10
Harkanwar S Gill, Funmilayo Tade, David Theodore Greenwald, Paul M Yonover, Bital Savir-Baruch
Prostate imaging with F-labeled 1-amino-3-fluorocyclobutane-1-carboxylic acid (FACBC, F-fluciclovine) PET/CT scan (Axumin) was recently approved by the US Food and Drug Administration for men with suspected prostate cancer recurrence based on elevated blood prostate-specific antigen levels following prior treatment. We present a rare case of a 77-year-old man with suspected recurrent prostate cancer with an incidental finding of advanced-stage breast cancer showing different degrees of F-fluciclovine uptake...
November 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29185295/complications-and-survival-of-megaprostheses-after-resection-of-bone-metastases
#11
M De Gori, A D’Arienzo, L Andreani, G Beltrami, D A Campanacci, P De Biase, F Frenos, S Giannotti, F Sacchetti, F Totti, P Parchi, R Capanna
Treatment of bone metastases is often palliative, aiming at pain control and stabilization or prevention of pathological fractures. However, a complete resection with healing purposes can be performed in selected cases. The aim of our work was to evaluate the survival of megaprostheses used for reconstruction after bone metastases. Between January 2001 and March 2015, we implanted 169 Megasystem-C® (Waldemar LINK® GmbH & Co. KG, Hamburg, Germany) after bone metastasis resection. Patients, 95 females and 74 males, were operated at an average age of 61 (12-87) years for proximal femoral resection in 135 (79...
October 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29180879/male-occult-triple-negative-breast-cancer-with-dermatomyositis-a-case-report-and-review-of-the-literature
#12
Le Zhang, Chenghua Zhang, Zhaoying Yang, Miao He, Lijuan Zhang, Shereen Ezzat, Xi Liang
Occult breast cancer is defined by the presence of axillary metastases without an identifiable primary breast tumor. Here, we report a rare case of a male occult breast cancer with dermatomyositis. We performed a modified radical mastectomy consisting of whole breast mastectomy and axillary lymph node dissection. Immunohistochemistry and fluorescent in situ hybridization analyses demonstrated an adenocarcinoma likely of breast origin, which was an occult triple-negative breast cancer. Interestingly, the patient's previously noted periorbital dermatomyositis resolved promptly following surgical excision...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29176636/genetic-and-clinical-characteristics-in-japanese-hereditary-breast-and-ovarian-cancer-first-report-after-establishment-of-hboc-registration-system-in-japan
#13
Masami Arai, Shiro Yokoyama, Chie Watanabe, Reiko Yoshida, Mizuho Kita, Megumi Okawa, Akihiro Sakurai, Masayuki Sekine, Junko Yotsumoto, Hiroyuki Nomura, Yoshinori Akama, Mayuko Inuzuka, Tadashi Nomizu, Takayuki Enomoto, Seigo Nakamura
The hereditary breast and ovarian cancer (HBOC) registration system of Japan was established by the Japanese HBOC Consortium. The first trial was registered in 2015 in four institutions to which some registration committee members belonged. We analyzed the information of 830 Japanese pedigrees, who underwent BRCA1/2 genetic testing, including mutation carriers with BRCA1 (N = 127) and BRCA2 (N = 115), and their families. The mutation-positive rate was 19.7%. Variants of uncertain significance were found in 6...
November 8, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/29174212/women-s-behaviors-toward-mammogram-and-pap-test-opportunities-to-increase-cervical-cancer-screening-participation-rates-among-older-women
#14
Simon M Tavasoli, Eli Kane, Anna M Chiarelli, Rachel Kupets
OBJECTIVES: Screening rates for cervical cancer remain moderate among women over 50 years of age. Because cervical and breast screening interventions can be linked, evaluating screening factors relating to both is important. This study evaluates factors associated with breast and cervical screening participation in women aged 52 to 69. METHODS: A cross-sectional study was used to describe characteristics associated with screening behaviors of 1,173,456 eligible women in Ontario, Canada...
November 23, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/29172261/knowledge-of-evidence-based-cancer-risk-factors-remains-low-among-new-zealand-adults-findings-from-two-cross-sectional-studies-2001-and-2015
#15
Rosalina Richards, Bronwen McNoe, Ella Iosua, Anthony I Reeder, Richard Egan, Louise Marsh, Lindsay Robertson, Brett Maclennan, Anna TF Latu, Robin Quigg, Anne-Cathrine Petersen
Objective: Cancer risk reduction messages are a part of cancer control efforts around the world. The complex reality is that risk factors differ for different types of cancer, making clear communication of desired behavioural changes more difficult. This study aims to describe awareness of risk factors for breast, bowel, cervical, prostate and lung cancer and cutaneous melanoma among New Zealanders in 2014/15 and identify changes in awareness since 2001. Methods: Two national telephone surveys, the first (CAANZ01) conducted in 2001, included 438 adults (231 females and 207 males, 64% response rate)...
November 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29170864/risk-of-malignancy-in-a-nationwide-cohort-of-elderly-inflammatory-bowel-disease-patients
#16
Nabeel Khan, Carlos Vallarino, Trevor Lissoos, Umar Darr, Michelle Luo
BACKGROUND: Management of elderly inflammatory bowel disease (IBD) patients (≥ 65 years of age) is complicated due to many factors, including a higher risk of cancer, which may impact therapeutic decisions. OBJECTIVE: The aim of this study was to determine the risk of cancer among elderly IBD patients compared with younger IBD patients. Additionally, the absolute risk of malignancy and factors contributing to it were evaluated, and therapeutic patterns among the elderly were assessed...
November 23, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/29165550/male-breast-cancer-pink-ribbon-blues
#17
P A Francis
No abstract text is available yet for this article.
November 20, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29156903/gender-differences-in-pain-and-patient-reported-outcomes-a-secondary-analysis-of-the-ncic-ctg-sc-23-randomized-trial
#18
Selina Chow, Keyue Ding, Bo Angela Wan, Michael Brundage, Ralph M Meyer, Abdenour Nabid, Pierre Chabot, Genevievev Coulombe, Shahida Ahmed, Joda Kuk, A Rashid Dar, Aamer Mahmud, Alysa Fairchild, Carolyn F Wilson, Jackson S Y Wu, Kristopher Dennis, Carlo DeAngelis, Rebecca K S Wong, Liting Zhu, Edward Chow
BACKGROUND: Gender differences may contribute to variations in disease presentations and health outcomes. To explore the gender difference in pain and patient reported outcomes in cancer patients with bone metastases undergoing palliative radiotherapy on the National Cancer Institute of Canada (NCIC) SC.23 randomized trial. METHODS: Patients completed the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life (QOL) bone metastases module (QLQ-BM22) and EORTC QOL Core-15-Palliative (QLQ-C15-PAL) before treatment and at days 10 and 42 after a single 8 Gy radiation treatment...
August 29, 2017: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/29151311/how-to-manage-pseudoangiomatous-stromal-hyperplasia-our-clinical-experience
#19
Emine Kurt, Sevim Turanlı, Fatma Markoç, Uğur Berberoğlu
Background/aim: Pseudoangiomatous stromal hyperplasia (PASH) is a rare and benign mesenchymal proliferative breast lesion. Our aim is to review the clinical and radiological features of PASH and define a standard approach for its diagnosis and management. Materials and methods: Clinical records of 35 consecutive patients with PASH were retrospectively reviewed between 2009 and 2015. Patients with clinically or radiologically detected mass and patients who underwent biopsy for other indications and were diagnosed incidentally were included in the study...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29150142/association-between-non-alcoholic-fatty-liver-disease-and-cancer-incidence-rate
#20
Gi-Ae Kim, Han Chu Lee, Jaewon Choe, Min-Ju Kim, Min Jung Lee, Hye-Sook Chang, In Young Bae, Hong-Kyu Kim, Jihyun An, Ju Hyun Shim, Kang Mo Kim, Young-Suk Lim
BACKGROUND & AIMS: Little is known about the association between non-alcoholic fatty liver disease (NAFLD) and cancer development. This study investigated the cancer incidence rates in NAFLD and analysed the association between NAFLD and cancer development. METHODS: This historical cohort study included subjects who were followed up for >1 year after having a heath checkup at a tertiary hospital in Korea from September 1, 2004 to December 31, 2005. NAFLD was diagnosed by ultrasonographic detection of hepatic steatosis in the absence of other known liver disease, including alcoholic or viral hepatitis...
November 2, 2017: Journal of Hepatology
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