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https://www.readbyqxmd.com/read/29475170/a-case-report-of-anterior-cruciate-ligament-and-posterolateral-corner-reconstruction-using-tendon-graft-preserved-in-situ
#1
Bosco Mpatswenumugabo, Emmanuel Bukara, Muhammed Semakula, Albert Nzayisenga, Rene Mukezamfura, Lambert Dusingizimana, Basile Habumugisha, Salvador Kamarampaka, Leon Mutesa, Alex Butera
INTRODUCTION: Combined anterior cruciate ligament (ACL) and posterolateral corner (PLC) reconstruction are a rare clinical entity in orthopedic literature, whose management requires different types of tendon grafts. Missed PLC injury leads to the failure of ACL repair due to the joint instability. PRESENTATION OF CASE: We are presenting a case of posttraumatic right ACL, PLC and lateral meniscus injury. The patient was taken to theatre for arthroscopic meniscectomy, ACL and PLC reconstruction...
February 17, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29474267/perspectives-on-integrated-hiv-and-hcv-testing-among-persons-entering-a-northern-california-jail-a-pilot-study
#2
Wilson Ly, Jennifer Cocohoba, Alexander Chyorny, Jodi Halpern, Colette Auerswald, Janet Myers
BACKGROUND: Providing HIV and HCV testing on an 'opt-out' basis is often considered the 'gold standard' because it contributes to higher testing rates when compared to 'opt-in' strategies. While rates are crucial, an individual's testing preferences are also important, especially in correctional settings where legal and social factors influence a person's capacity to freely decide whether or not to test. Our study explored factors influencing HIV and HCV testing decisions and individuals' preferences and concerns regarding opt-in versus opt-out testing at the time of jail entry...
February 22, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29474238/management-of-early-cervical-stromal-invasion-figo-stage-1a1-when-margins-are-involved-with-cervical-intraepithelial-neoplasia
#3
Rachel C Nicholson, Jeremy Twigg, Alison Roberts, Georgios Angelopoulos, Derek Cruickshank
OBJECTIVE: Women with International Federation of Gynecology and Obstetrics stage 1A1 cervical carcinoma were evaluated to determine whether repeat excision for large loop excision transformation zone margins positive with cervical intraepithelial neoplasia (CIN) had been undertaken according to the National Health Service Cervical Screening Programme guidelines and if deviations from guidelines adversely affected patient outcome. MATERIALS AND METHODS: We retrospectively studied patients with 1A1 cervical carcinoma treated in our service between May 2010 and July 2015 to determine whether NHSCSP guidelines (May 2010) were followed...
February 23, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474098/comparing-four-radiotherapy-techniques-for-treating-the-chest-wall-plus-levels-iii-iv-draining-nodes-after-breast-reconstruction
#4
Valentina Lancellotta, Martina Iacco, Elisabetta Perrucci, Lorenzo Falcinelli, Claudio Zucchetti, Berardino de Bari, Simonetta Saldi, Cynthia Aristei
OBJECTIVE: To compare the dosimetric outcomes of four radiotherapy (RT) techniques for treating the chest wall plus draining nodes after mastectomy and breast reconstruction. METHODS: Three-dimensional conformal radiotherapy (3DCRT), linac-based intensity modulated radiotherapy, helical tomotherapy (HT) and direct tomotherapy (DT) treatments were planned for 40 breast cancer patients. Dose prescription was 50 Gy. Plans were compared in terms of doses to the planning target volume, organs at risk (OARs) and the homogeneity index (HI)...
February 23, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29473156/new-evidence-on-employment-effects-of-informal-care-provision-in-europe
#5
Ingo W K Kolodziej, Arndt R Reichert, Hendrik Schmitz
OBJECTIVE: To estimate how labor force participation is affected when adult children provide informal care to their parents. DATA SOURCE: Survey of Health, Ageing and Retirement in Europe from 2004 to 2013. STUDY DESIGN: To offset the problem of endogeneity, we exploit the availability of other potential caregivers within the family as predictors of the probability to provide care for a dependent parent. Contrary to most previous studies, the dataset covers the whole working-age population in the majority of European countries...
February 22, 2018: Health Services Research
https://www.readbyqxmd.com/read/29472177/implementation-of-the-enhanced-moderated-online-social-therapy-most-model-within-a-national-youth-e-mental-health-service-eheadspace-protocol-for-a-single-group-pilot-study-for-help-seeking-young-people
#6
Simon Rice, John Gleeson, Steven Leicester, Sarah Bendall, Simon D'Alfonso, Tamsyn Gilbertson, Eoin Killackey, Alexandra Parker, Reeva Lederman, Greg Wadley, Olga Santesteban-Echarri, Ingrid Pryor, Daveena Mawren, Aswin Ratheesh, Mario Alvarez-Jimenez
BACKGROUND: There is a substantial need for youth electronic mental health (e-mental health) services. In addressing this need, our team has developed a novel moderated online social therapy intervention called enhanced moderated online social therapy (MOST+). MOST+ integrates real-time, clinician-delivered Web chat counseling, interactive user-directed online therapy, expert and peer moderation, and private and secure peer-to-peer social networking. MOST+ has been designed to give young people immediate, 24-hour access to anonymous, evidence-based, and short-term mental health care...
February 22, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29470950/not-seeking-yet-trying-long-acting-reversible-contraception-a-24-month-randomized-trial-on-continuation-unintended-pregnancy-and-satisfaction
#7
David Hubacher, Hannah Spector, Charles Monteith, Pai-Lien Chen
OBJECTIVES: To measure the 24-month impact on continuation, unintended pregnancy, and satisfaction of trying long-acting reversible contraception (LARC) in a population seeking short-acting reversible contraception (SARC). STUDY DESIGN: We enrolled 916 women aged 18-29 who were seeking pills or injectables in a partially randomized patient preference trial. Women with strong preferences for pills or injectables, started on those products, while others opted for randomization to LARC or SARC and received their methods gratis...
February 19, 2018: Contraception
https://www.readbyqxmd.com/read/29470863/the-evolution-of-mollusc-shells
#8
REVIEW
Carmel McDougall, Bernard M Degnan
Molluscan shells are externally fabricated by specialized epithelial cells on the dorsal mantle. Although a conserved set of regulatory genes appears to underlie specification of mantle progenitor cells, the genes that contribute to the formation of the mature shell are incredibly diverse. Recent comparative analyses of mantle transcriptomes and shell proteomes of gastropods and bivalves are consistent with shell diversity being underpinned by a rapidly evolving mantle secretome (suite of genes expressed in the mantle that encode secreted proteins) that is the product of (a) high rates of gene co-option into and loss from the mantle gene regulatory network, and (b) the rapid evolution of coding sequences, particular those encoding repetitive low complexity domains...
February 22, 2018: Wiley Interdisciplinary Reviews. Developmental Biology
https://www.readbyqxmd.com/read/29469885/sixth-order-wave-aberration-theory-of-ultrawide-angle-optical-systems-erratum
#9
Lijun Lu, Yiqing Cao
In this erratum, two errors in our recently published paper [Appl. Opt.56, 8570 (2017)APOPAI0003-693510.1364/AO.56.008570] are corrected.
February 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29468325/correction-to-role-of-membrane-glycerolipids-in-photosynthesis-thylakoid-biogenesis-and-chloroplast-development
#10
Koichi Kobayashi
The article "Role of membrane glycerolipids in photosynthesis, thylakoid biogenesis and chloroplast development", written by "Koichi Kobayashi", was originally published Online First without open access. After publication in volume 129, issue 4, page 565-580 the Botanical Society of Japan decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to
February 21, 2018: Journal of Plant Research
https://www.readbyqxmd.com/read/29468322/correction-to-plant-actin-depolymerizing-factor-actin-microfilament-disassembly-and-more
#11
Noriko Inada
The article "Plant actin depolymerizing factor: actin microfilament disassembly and more", written by "Noriko Inada", was originally published Online First without open access. After publication in volume 130, issue 2, page 227-238 the Botanical Society of Japan decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to
February 21, 2018: Journal of Plant Research
https://www.readbyqxmd.com/read/29468321/correction-to-metabolism-of-l-arabinose-in-plants
#12
Toshihisa Kotake, Yukiko Yamanashi, Chiemi Imaizumi, Yoichi Tsumuraya
The article "Metabolism of L-arabinose in plants", written by "Toshihisa Kotake, Yukiko Yamanashi, Chiemi Imaizumi, Yoichi Tsumuraya", was originally published Online First without open access. After publication in volume129, issue 5, page 781-792 the Botanical Society of Japan decided to opt for Open Choice and to make the article an open access publication.
February 21, 2018: Journal of Plant Research
https://www.readbyqxmd.com/read/29468056/implementation-of-universal-rapid-human-immunodeficiency-virus-screening-on-labor-and-delivery
#13
Stacia Crochet, Chun-Chih Huang, Melissa Fries, Rachel K Scott
Background: A case of mother to child transmission (MTCT) of HIV at a medical center in Washington, DC, resulted in the implementation of universal opt-out rapid testing of patients admitted for delivery. This article evaluates the policy's efficacy and implementation. Methods: We evaluated the implementation using the Reach, Efficacy, Adoption, Implementation, and Maintenance (RE-AIM) framework. Results: We could not evaluate decrease in MTCT rate secondary to low sample size ( n  = 3324) and no true-positive results...
March 2018: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/29467976/improving-resident-use-of-mental-health-resources-it-s-time-for-an-opt-out-strategy-to-address-physician-burnout-and-depression-commentary
#14
Maneesh Batra, Heather McPhillips, Richard Shugerman
No abstract text is available yet for this article.
February 2018: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/29467975/implementing-a-universal-well-being-assessment-to-mitigate-barriers-to-resident-utilization-of-mental-health-resources
#15
Sarah Sofka, Carl Grey, Nathan Lerfald, Laura Davisson, Janie Howsare
Background : Physician utilization of well-being resources remains low despite efforts to promote use of these resources. Objective : We implemented a well-being assessment for internal medicine residents to improve access and use of mental health services. Methods : We scheduled all postgraduate year 1 (PGY-1) and PGY-2 residents at West Virginia University for the assessment at our faculty and staff assistance program (FSAP). While the assessment was intended to be universal (all residents), we allowed residents to "opt out...
February 2018: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/29467316/the-formation-of-rna-granule-derived-capsid-assembly-intermediates-appears-to-be-conserved-between-hiv-1-and-the-non-primate-lentivirus-fiv
#16
Jonathan C Reed, Nick Westergreen, Brook C Barajas, Dylan T B Ressler, Daryl J Phuong, John V Swain, Vishwanath R Lingappa, Jaisri R Lingappa
During immature capsid assembly in cells, HIV-1 Gag co-opts a host RNA granule, forming a pathway of intracellular assembly intermediates containing host components, including two cellular facilitators of assembly, ABCE1 and DDX6. A similar assembly pathway has been observed for other primate lentiviruses. Here we asked whether feline immunodeficiency virus (FIV), a non-primate lentivirus, also forms RNA-granule-derived capsid assembly intermediates. First, we showed that the released FIV immature capsid and a large FIV-Gag-containing intracellular complex are unstable during analysis, unlike for HIV-1...
February 21, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29466324/sequences-enriched-in-alu-repeats-drive-nuclear-localization-of-long-rnas-in-human-cells
#17
Yoav Lubelsky, Igor Ulitsky
Long noncoding RNAs (lncRNAs) are emerging as key players in multiple cellular pathways1 , but their modes of action and how those are dictated by sequence remain unclear. lncRNAs tend to be enriched in the nuclear fraction, whereas most mRNAs are overtly cytoplasmic2 , although several studies have found that hundreds of mRNAs in various cell types are retained in the nucleus3,4 . It is thus conceivable that some mechanisms that promote nuclear enrichment are shared between lncRNAs and mRNAs. In order to identify elements that can force nuclear localization in lncRNAs and mRNAs we screened libraries of short fragments tiled across nuclear RNAs, which were cloned into the untranslated regions of an efficiently exported mRNA...
January 24, 2018: Nature
https://www.readbyqxmd.com/read/29465706/creating-innovative-sti-testing-options-for-university-students-the-impact-of-an-sti-self-testing-program
#18
Melissa A Habel, Kathryn A Brookmeyer, Robin Oliver-Veronesi, Shelley Haffner
BACKGROUND: National-level data suggest that STI testing rates among young adults are low. The purpose of this study was to evaluate the acceptability of an STI self-testing program at a university health center. Few evaluations have been conducted on the acceptability of collegiate self-testing programs and their effect on testing uptake. METHODS: To assess acceptability and uptake of self-testing (urine and SCVS), we conducted a brief self-administered survey of students accessing a large US-based university health center from January - December 2015...
October 4, 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29464148/immediate-breast-reconstruction-among-patients-with-medicare-and-private-insurance-a-matched-cohort-analysis
#19
Parisa Kamali, Joseph A Ricci, Daniel A Curiel, Justin B Cohen, Anmol Chattha, Hinne A Rakhorst, Bernard T Lee, Samuel J Lin
Background: By eliminating economic hurdles, the Women's Health and Cancer Rights Act of 1998 represented a paradigm shift in the availability of breast reconstruction. Yet, studies report disparities among Medicare-insured women. These studies do not account for the inherent differences in age and comorbidities between a younger privately insured and an older Medicare population. We examined immediate breast reconstruction (IBR) utilization between a matched pre- and post-Medicare population...
January 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29464017/regulation-of-e-cadherin-localization-by-microtubule-targeting-agents-rapid-promotion-of-cortical-e-cadherin-through-p130cas-src-inhibition-by-eribulin
#20
Nicholas F Dybdal-Hargreaves, April L Risinger, Susan L Mooberry
Microtubule targeting agents (MTAs) are some of the most effective anticancer drugs used to treat a wide variety of adult and pediatric cancers. Building evidence suggests that these drugs inhibit interphase signaling events and that this contributes to their anticancer actions. The effects of diverse MTAs were evaluated following a 2 hour incubation with clinically relevant concentrations to test the hypothesis that these drugs rapidly and differentially disrupt epithelial-to-mesenchymal transition (EMT)-related signaling...
January 19, 2018: Oncotarget
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