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https://www.readbyqxmd.com/read/28526046/balloon-versus-stenting-in-severe-ischaemia-of-the-leg-3-basil-3-study-protocol-for-a-randomised-controlled-trial
#1
Benjamin D Hunt, Matthew A Popplewell, Huw Davies, Lewis Meecham, Hugh Jarrett, Gareth Bate, Margaret Grant, Smitaa Patel, Catherine Hewitt, Lazaros Andronis, Jonathan J Deeks, Andrew Bradbury
BACKGROUND: Severe limb ischaemia (SLI) is defined as the presence of rest pain and/or tissue loss secondary to lower extremity atherosclerotic peripheral arterial disease. The superficial femoral and popliteal arteries are the most commonly diseased vessels in such patients and are being increasingly treated using endovascular revascularisation techniques. However, it is currently unknown whether drug-eluting stents and drug-coated balloons confer additional clinical benefits over more established techniques using plain balloons and bare metal stents, or whether they represent a cost-effective use of NHS resources...
May 19, 2017: Trials
https://www.readbyqxmd.com/read/28520106/prophylactic-sustained-inflation-is-just-one-step-to-preventing-bronchopulmonary-dysplasia
#2
G Lista, I Bresesti
I am glad to see that the Sustained Lung Inflation (SLI) trial (1) still draws a great deal of attention and I would like to clarify some aspects of the trial, in response to the comments by Gupta and Argarwal (2) in Acta Paediatrica. A meta-analysis carried out in 2016 demonstrated that starting non-invasive respiratory support from birth could reduce the incidence of bronchopulmonary dysplasia and death. However, about 50% of very low birth weight infants who are initially on nasal continuous positive airway pressure need subsequent intubation and mechanical ventilation...
May 18, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28510615/the-role-of-frequency-in-learning-morphophonological-alternations-implications-for-children-with-specific-language-impairment
#3
Ekaterina Tomas, Katherine Demuth, Peter Petocz
Purpose: The aim of this article was to explore how the type of allomorph (e.g., past tense buzz[d] vs. nod[əd]) influences the ability to perceive and produce grammatical morphemes in children with typical development and with specific language impairment (SLI). Method: The participants were monolingual Australian English-speaking children. The SLI group included 13 participants (mean age = 5;7 [years;months]); the control group included 19 children with typical development (mean age = 5;4)...
May 16, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28504353/cmip-haploinsufficiency-in-two-patients-with-autism-spectrum-disorder-and-co-occurring-gastrointestinal-issues
#4
Minjie Luo, Jinbo Fan, Tara L Wenger, Margaret H Harr, Melissa Racobaldo, Surabhi Mulchandani, Holly Dubbs, Elaine H Zackai, Nancy B Spinner, Laura K Conlin
Autism spectrum disorder (ASD) is a genetically heterogeneous group of disorders characterized by impairments in social communication and restricted interests. Though some patients with ASD have an identifiable genetic cause, the cause of most ASD remains elusive. Many ASD susceptibility loci have been identified through clinical studies. We report two patients with syndromic ASD and persistent gastrointestinal issues who carry de novo deletions involving the CMIP gene detected by genome-wide SNP microarray and fluorescence in situ hybridization (FISH) analysis...
May 15, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28486941/neuroprotective-effect-of-salvianolate-lyophilized-injection-against-cerebral-ischemia-in-type-1-diabetic-rats
#5
Fujiang Wang, Qiansong He, Jinxin Wang, Qing Yuan, Hong Guo, Lijuan Chai, Shaoxia Wang, Limin Hu, Yue Zhang
BACKGROUND: Salvianolate lyophilized injection (SLI) has been clinically used in China for the treatment of acutely cerebral infarction. Clinical and experimental studies have shown that Diabetes mellitus (DM) not only increases the risk of ischemic stroke recurrence but also leads to poor outcomes and increases fatality rates after stroke. Our previous study has proved that SLI can reduce the infarct volume after stroke in type 1 diabetic rats. The aim of the study is to explore the mechanism of SLI on stroke outcome in type 1 diabetic (T1DM) rats...
May 10, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28486125/can-you-spell-dyslexia-without-sli-comparing-the-cognitive-profiles-of-dyslexia-and-specific-language-impairment-and-their-roles-in-learning
#6
Tracy Packiam Alloway, Furtuna Tewolde, Dakota Skipper, David Hijar
The aim of the present study is to explore whether those with Specific Language Impairment (SLI) and dyslexia display distinct or overlapping cognitive profiles with respect to learning outcomes. In particular, we were interested in two key cognitive skills associated with academic performance - working memory and IQ. We recruited three groups of children - those with SLI, those with dyslexia, and a control group. All children were given standardized tests of working memory, IQ (vocabulary and matrix), spelling, and math...
May 6, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28486046/grammatical-case-marking-in-japanese-children-with-sli
#7
Aimi Murao, Tomohiko Ito, Suzy E Fukuda, Shinji Fukuda
The purpose of this study was to investigate whether or not Japanese children with specific language impairment (henceforth; SLI) would in fact experience difficulty with grammatical case-marking. The participants were 10 Japanese children with SLI, aged 7;7 to 11;4, and 25 Japanese children with typical language development (henceforth; TLD), aged 8;11 to 9;11. In this study, a sentence completion task was used, which involved both active and passive sentences with canonical and scrambled word order. The children with SLI were significantly less accurate than those with TLD with the use of grammatical case-markers...
May 9, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28483302/preoperative-chemoradiotherapy-for-rectal-cancer-and-impact-on-outcomes-a-population-based-study
#8
Linn M Åsli, Tom B Johannesen, Tor Å Myklebust, Bjørn Møller, Morten Tandberg Eriksen, Marianne Grønlie Guren
BACKGROUND AND PURPOSE: Preoperative (chemo)radiotherapy ((C)RT) for rectal cancer is, in Norway, restricted to patients with cT4-stage or threatened circumferential resection margin. This nationwide population-based study assessed the use of preoperative (C)RT in Norway and its impact on treatment outcomes. PATIENTS AND METHODS: Data from The Norwegian Colorectal Cancer Registry were used to identify all stage I-III rectal cancers treated with major resection (1997-2011: n=9193)...
May 5, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28481668/the-development-of-writing-skills-in-4-year-old-children-with-and-without-specific-language-impairment
#9
Stacey L Pavelko, R Jane Lieberman, Jamie Schwartz, Debbie Hahs-Vaughn, Chad Nye
Research shows that many preschool children with specific language impairment (SLI) have difficulty acquiring literacy skills including phonological awareness, print concepts, and alphabet knowledge. Limited research suggests that preschool children with SLI also have difficulty with emergent writing tasks such as name writing and word writing. In typically developing children, research indicates that emergent writing skills are acquired in a developmental sequence: (1) linearity, (2) segmentation, (3) simple characters, (4) left-right orientation, (5) complex characters, (6) random letters, and (7) invented spelling...
May 8, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28474204/screening-for-specific-language-impairment-in-preschool-children-evaluating-a-screening-procedure-including-the-token-test
#10
Ulrike Willinger, Michaela Schmoeger, Matthias Deckert, Brigitte Eisenwort, Benjamin Loader, Annemarie Hofmair, Eduard Auff
Specific language impairment (SLI) comprises impairments in receptive and/or expressive language. Aim of this study was to evaluate a screening for SLI. 61 children with SLI (SLI-children, age-range 4-6 years) and 61 matched typically developing controls were tested for receptive language ability (Token Test-TT) and for intelligence (Wechsler Preschool-and-Primary-Scale-of-Intelligence-WPPSI). Group differences were analyzed using t tests, as well as direct and stepwise discriminant analyses. The predictive value of the WPPSI with respect to TT performance was analyzed using regression analyses...
May 4, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/28470886/theory-of-mind-in-sli-revisited-links-with-syntax-comparisons-with-asd
#11
Stephanie Durrleman, Morgane Burnel, Anne Reboul
BACKGROUND: According to the linguistic determinism approach, knowledge of sentential complements such as: John says that the earth is flat plays a crucial role in theory of mind (ToM) development by providing a means to represent explicitly people's mental attitudes and beliefs. This approach predicts that mastery of complements determines successful belief reasoning across explicit ToM tasks, even low-verbal ones, and across populations. AIMS: (1) To investigate the link between a low-verbal ToM-task and complements in Specific Language Impairment (SLI), (2) To determine whether this population shows similar ToM performance to that of children with Autism Spectrum Disorder (ASD) or those with Typical Development (TD) once these groups are matched on competency for complements, (3) To explore whether complements conveying a falsehood without jeopardizing the veracity of the entire sentence, such as complements of verbs of communication, are more crucial for belief attribution than complements which do not have this property, namely complements of verbs of perception, (?John sees that the earth is flat)...
May 4, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28464253/statistical-word-learning-in-children-with-autism-spectrum-disorder-and-specific-language-impairment
#12
Eileen Haebig, Jenny R Saffran, Susan Ellis Weismer
BACKGROUND: Word learning is an important component of language development that influences child outcomes across multiple domains. Despite the importance of word knowledge, word-learning mechanisms are poorly understood in children with specific language impairment (SLI) and children with autism spectrum disorder (ASD). This study examined underlying mechanisms of word learning, specifically, statistical learning and fast-mapping, in school-aged children with typical and atypical development...
May 2, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28441074/assessing-lebanese-bilingual-children-the-use-of-cross-linguistic-lexical-tasks-in-lebanese-arabic
#13
Christel Khoury Aouad Saliby, Christophe Dos Santos, Edith Kouba Hreich, Camille Messarra
Since norms for vocabulary acquisition in Lebanese bilingual children (L1: Lebanese, L2: French and/or English) do not yet exist, clinical assessment based on normative data and using appropriate tools remains difficult for speech and language therapists. The current study focuses on exploring and comparing lexical performances of typically developing Lebanese bilingual children (32 Bi-TD, aged 5;7 to 6;9) and those with specific language impairment (10 Bi-SLI, aged 5;9 to 7;10), using cross-linguistic lexical tasks (LITMUS-CLT, COST Action IS0804, 2011) in Lebanese Arabic language (CLT-LB), specific to the Lebanese context...
April 25, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28425302/probing-morphological-syntactic-and-pragmatic-knowledge-through-answers-to-wh-questions-in-children-with-sli
#14
Kelly Rombough, Rosalind Thornton
PURPOSE: This study investigated aspects of morphology, syntax and pragmatics in children with Specific Language Impairment (SLI). These areas of language were investigated by evaluating children's answers to wh-questions. METHOD: Elicited production methodology was used to evoke answers to three types of wh-questions. There were 54 participants: 18 children with SLI (mean age = 5;3); 18 language-matched children matched on mean length of utterance (mean age = 3;4) and 18 age-matched children (mean age = 5;3)...
February 14, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28421645/grammaticality-differences-between-spanish-speaking-children-with-specific-language-impairment-and-their-typically-developing-peers
#15
Donna Jackson-Maldonado, Ricardo Maldonado
BACKGROUND: A limited number of studies have analyzed grammaticality in monolingual Spanish-speaking children with specific language impairment (SLI). Most of the available data are based on bilingual speakers. AIMS: To extend previous studies by doing a more detailed analysis of grammatical types in monolingual Spanish-speakers with and without SLI. METHODS & PROCEDURES: Forty-nine Spanish-speaking children (18 with SLI, 17 age-matched typically developing controls, 14 language-matched controls) were recruited from schools in Mexico and observed in a spontaneous narrative task...
April 18, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28419188/interactive-book-reading-to-accelerate-word-learning-by-kindergarten-children-with-specific-language-impairment-identifying-adequate-progress-and-successful-learning-patterns
#16
Holly L Storkel, Rouzana Komesidou, Kandace K Fleming, Rebecca Swinburne Romine
Purpose: The goal of this study was to provide guidance to clinicians on early benchmarks of successful word learning in an interactive book reading treatment and to examine how encoding and memory evolution during treatment contribute to word learning outcomes by kindergarten children with specific language impairment (SLI). Method: Twenty-seven kindergarten children with SLI participated in a preliminary clinical trial using interactive book reading to teach 30 new words...
April 20, 2017: Language, Speech, and Hearing Services in Schools
https://www.readbyqxmd.com/read/28400738/grammar-is-differentially-impaired-in-subgroups-of-autism-spectrum-disorders-evidence-from-an-investigation-of-tense-marking-and-morphosyntax
#17
Nadezhda Modyanova, Alexandra Perovic, Ken Wexler
Deficits in the production of verbal inflection (tense marking, or finiteness) are part of the Optional Infinitive (OI) stage of typical grammatical development. They are also a hallmark of language impairment: they have been used as biomarkers in guiding genetic studies of Specific Language Impairment (SLI), and have also been observed in autism spectrum disorders (ASD). To determine the detailed nature of finiteness abilities in subgroups of ASD [autism with impaired language (ALI) vs. autism with normal language (ALN)], we compared tense marking abilities in 46 children with ALI and 37 children with ALN with that of two groups of nonverbal mental age (MA) and verbal MA-matched typically developing (TD) controls, the first such study described in the literature...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28390599/medial-olivocochlear-function-in-children-with-poor-speech-in-noise-performance-and-language-disorder
#18
Caroline Nunes Rocha-Muniz, Renata Mota Mamede Carvallo, Eliane Schochat
OBJECTIVES: Contralateral masking of transient-evoked otoacoustic emissions is a phenomenon that suggests an inhibitory effect of the olivocochlear efferent auditory pathway. Many studies have been inconclusive in demonstrating a clear connection between this system and a behavioral speech-in-noise listening skill. The purpose of this study was to investigate the activation of a medial olivocochlear (MOC) efferent in children with poor speech-in-noise (PSIN) performance and children with language impairment and PSIN (SLI + PSIN)...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28380200/alliteration-and-rhyme-skills-in-children-with-specific-language-impairment
#19
Paula Renata Pedott, Ana Manhani Cáceres-Assenço, Debora Maria Befi-Lopes
Purpose: this study investigated and compared the performance of school-aged children with specific language impairment (SLI) and their peers typically developing language in alliteration and rhyme tests. The study also aimed to evaluate the influence of semantic and phonological distractors on both tests. Methods: twelve school-aged children with SLI (study group - SG) and 48 peers typically developing language (control group - CG) aged 7 to 9 years. All of them were on 2nd or 3rd grade and presented hearing thresholds within normal limits and appropriate nonverbal intellectual performance...
March 30, 2017: CoDAS
https://www.readbyqxmd.com/read/28375697/iteration-of-partially-specified-target-matrices-application-to-the-bi-factor-case
#20
Francisco J Abad, Eduardo Garcia-Garzon, Luis E Garrido, Juan R Barrada
The current study proposes a new bi-factor rotation method, Schmid-Leiman with iterative target rotation (SLi), based on the iteration of partially specified target matrices and an initial target constructed from a Schmid-Leiman (SL) orthogonalization. SLi was expected to ameliorate some of the limitations of the previously presented SL bi-factor rotations, SL and SL with target rotation (SLt), when the factor structure either includes cross-loadings, near-zero loadings, or both. A Monte Carlo simulation was carried out to test the performance of SLi, SL, SLt, and the two analytic bi-factor rotations, bi-quartimin and bi-geomin...
April 4, 2017: Multivariate Behavioral Research
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