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https://www.readbyqxmd.com/read/27904612/a-systematic-review-on-diagnostic-procedures-for-specific-language-impairment-the-sensitivity-and-specificity-issues
#1
REVIEW
Toktam Maleki Shahmahmood, Shohreh Jalaie, Zahra Soleymani, Fatemeh Haresabadi, Parvin Nemati
BACKGROUND: Identification of children with specific language impairment (SLI) has been viewed as both necessity and challenge. Investigators and clinicians use different tests and measures for this purpose. Some of these tests/measures have good psychometric properties, but it is not sufficient for diagnostic purposes. A diagnostic procedure can be used for identification a specific population with confidence only when its sensitivity and specificity are acceptable. In this study, we searched for tests/measures with predefined sensitivity and specificity for identification of preschool children with SLI from their typically developing peers...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27884866/a-case-of-specific-language-impairment-in-a-deaf-signer-of-american-sign-language
#2
David Quinto-Pozos, Jenny L Singleton, Peter C Hauser
This article describes the case of a deaf native signer of American Sign Language (ASL) with a specific language impairment (SLI). School records documented normal cognitive development but atypical language development. Data include school records; interviews with the child, his mother, and school professionals; ASL and English evaluations; and a comprehensive neuropsychological and psychoeducational evaluation, and they span an approximate period of 7.5 years (11;10-19;6) including scores from school records (11;10-16;5) and a 3...
November 23, 2016: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/27867370/theory-of-mind-deficits-and-social-emotional-functioning-in-preschoolers-with-specific-language-impairment
#3
REVIEW
Constance Vissers, Sophieke Koolen
Children with Specific Language Impairment (SLI) often experience emotional and social difficulties. In general, problems in social emotional functioning can be cognitively explained in terms of Theory of Mind (ToM). In this mini-review, an overview is provided of studies on social-emotional functioning and ToM in preschoolers (average age from 2.3 to 6.2 years) with SLI. It is concluded that, similar to school-aged children with SLI, preschoolers with SLI have several social-emotional problems and that both cognitive and affective aspects of ToM are impaired in those children...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27851795/health-related-quality-of-life-for-children-and-adolescents-with-specific-language-impairment-a-cohort-study-by-a-learning-disabilities-reference-center
#4
Gaëlle Hubert-Dibon, Marie Bru, Christèle Gras Le Guen, Elise Launay, Arnaud Roy
OBJECTIVES: To assess the health-related quality of life (HRQOL) of children with specific language impairment (SLI). STUDY DESIGN: In a prospective sample at a Learning Disabilities Reference Center, proxy-rated HRQOL (KIDSCREEN-27) was assessed for children with SLI and unaffected children from January 1, 2014 to March 31, 2015. Quality of life predictors for children with SLI were evaluated by recording the length and number of speech therapy and psychotherapy sessions and the specific school organization that the children had participated in...
2016: PloS One
https://www.readbyqxmd.com/read/27827330/insulin-resistance-is-a-risk-factor-for-silent-lacunar-infarction
#5
Ji Eun Lee, Dong Wook Shin, Jae Moon Yun, Sang Hyuck Kim, You-Seon Nam, BeLong Cho, Jae-Sung Lim, Han-Yeong Jeong, Hyung-Min Kwon, Jin-Ho Park
BACKGROUND AND PURPOSE: This study aims to investigate the association between insulin resistance (IR) and silent lacunar infarction (SLI) in healthy adults. METHODS: We recruited 2326 healthy Korean adults who took health checkups, including a brain magnetic resonance imaging. SLI was defined as an infarction measuring 0.3 to 1.5 cm in diameter that was localized in the territory of perforating branches of cerebral arteries, as seen in the brain magnetic resonance imaging...
November 8, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27819251/reconstruction-of-high-resolution-mlc-leaf-positions-using-a-low-resolution-detector-for-accurate-3d-dose-reconstruction-in-imrt
#6
R Visser, J Godart, D J L Wauben, J A Langendijk, A A Van't Veld, E W Korevaar
In pre-treatment dose verification, low resolution detector systems are unable to identify shifts of individual leafs of high resolution multi leaf collimator (MLC) systems from detected changes in the dose deposition. The goal of this study was to introduce an alternative approach (the shutter technique) combined with a previous described iterative reconstruction method to accurately reconstruct high resolution MLC leaf positions based on low resolution measurements. For the shutter technique, two additional radiotherapy treatment plans (RT-plans) were generated in addition to the original RT-plan; one with even MLC leafs closed for reconstructing uneven leaf positions and one with uneven MLC leafs closed for reconstructing even leaf positions...
December 7, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27792257/scanning-plane-comparison-of-ultrasound-derived-morphological-characteristics-of-the-vastus-lateralis
#7
Alyssa N Varanoske, David H Fukuda, Carleigh H Boone, Kyle S Beyer, Jeffrey R Stout, Jay R Hoffman
Muscle morphological characteristics obtained via ultrasonography have been used to quantify the size, architecture, and quality of skeletal muscle. Previous research has utilized varying ultrasonographic techniques, however there is little information comparing these different techniques. Muscle morphological characteristics, including cross-sectional area (CSA), muscle thickness (MT), echo intensity (EI), and subcutaneous adipose tissue thickness (SubQ) were assessed in 24 males (20.2 ± 1.6 y) via three panoramic-images captured in the transverse plane (PTI) and three still-images captured in the longitudinal plane (SLI)...
October 28, 2016: Clinical Anatomy
https://www.readbyqxmd.com/read/27790102/the-calculation-of-language-lateralization-indices-in-post-stroke-aphasia-a-comparison-of-a-standard-and-a-lesion-adjusted-formula
#8
Aimee Dietz, Jennifer Vannest, Thomas Maloney, Mekibib Altaye, Jerzy P Szaflarski, Scott K Holland
Background: The language lateralization index (LI) is a valuable tool in functional magnetic resonance imaging (fMRI) research, especially in people with post-stroke aphasia. However, there is inconsistent consideration for the overlap of lesions with regions of interest (ROIs). The purpose of this study was to determine whether standard LI (SLI) and lesion-adjusted LI (LALI) formulae generate different LI values and language lateralization classification for people with post-stroke chronic aphasia. Methods: SLI and LALI were calculated for an event-related (overt) verb generation task in an anterior and a posterior language ROI...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27789385/nocebo-hyperalgesia-and-the-startle-response
#9
Per M Aslaksen, Ole Åsli, Morten Øvervoll, Espen Bjørkedal
BACKGROUND: The literature on the effects of nocebo on pain is sparse. The present experimental study investigated whether suggestions of nocebo hyperalgesia modified the startle response and whether increased startle contributed to the nocebo hyperalgesic effect. METHODS: A design with four groups was employed; the participants were randomized into either a placebo group, a natural history group, or into two nocebo groups. The participants in the placebo and nocebo groups received suggestions of pain decrease or pain increase, together with a placebo or nocebo cream applied to the lower arm, respectively...
December 17, 2016: Neuroscience
https://www.readbyqxmd.com/read/27788275/processing-binding-relations-in-specific-language-impairment
#10
Richard G Schwartz, Arild Hestvik, Liat Seiger-Gardner, Diana Almodovar
Purpose: This sentence processing experiment examined the abilities of children with specific language impairment (SLI) and children with typical language development (TD) to establish relations between pronouns or reflexives and their antecedents in real time. Method: Twenty-two children with SLI and 24 age-matched children with TD (7;3-10;11 [years;months]) participated in a cross-modal picture priming experiment to determine whether they selectively activated the correct referent at the pronoun or reflexive in sentences...
October 27, 2016: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/27784351/-establishment-of-mouse-model-with-humanized-chronic-myeloid-leukemia
#11
Yu-Jie Xu, Wen-Hua Jia, Cang-Chun Liu, Wan-Ru Chen, De-Peng Li, Yi-Hong Huang
OBJECTIVE: To establish a BALB/c nude mouse model with the huamanized chronic myeloid leukemia (CML) for the study of human CML. METHODS: The BALB/c nude mice aged 4 weeks pretreated by splenectomy, the cyclophosphamide intraperitoneal injection and sublethal irradiation (SLI) were transplanted intravenously with bone marrow mononuclear cells from CML patients. The SLI-pretreated nude mice were divided into 2 groups: group A, in which the nude mice were injected with 0...
October 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/27748867/effect-of-salvia-miltiorrhiza-and-ligustrazine-injection-on-myocardial-ischemia-reperfusion-and-hypoxia-reoxygenation-injury
#12
Wendong Huang, Yongfei Yang, Zhi Zeng, Meiling Su, Qi Gao, Banghao Zhu
Salvia miltiorrhiza and ligustrazine are traditional Chinese medicines that have been used in combination for treatment of cardiovascular disease, including coronary heart disease, cardiac angina and atherosclerosis in Asia, in particular, China. The present study aimed to determine the effect of S. miltiorrhiza and ligustrazine injection (SLI) on myocardial ischemia/reperfusion (I/R) and hypoxia/reoxygenation (H/R) injuries via the Akt serine/threonine kinase (Akt)‑endothelial nitric oxide synthase (eNOS) signaling pathway...
November 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27701707/children-with-specific-language-impairment-and-their-families-a-future-view-of-nature-plus-nurture-and-new-technologies-for-comprehensive-language-intervention-strategies
#13
Mabel L Rice
Future perspectives on children with language impairments are framed from what is known about children with specific language impairment (SLI). A summary of the current state of services is followed by discussion of how these children can be overlooked and misunderstood and consideration of why it is so hard for some children to acquire language when it is effortless for most children. Genetic influences are highlighted, with the suggestion that nature plus nurture should be considered in present as well as future intervention approaches...
November 2016: Seminars in Speech and Language
https://www.readbyqxmd.com/read/27701629/dose-schedule-and-enhanced-conversational-recast-treatment-for-children-with-specific-language-impairment
#14
Christina N Meyers-Denman, Elena Plante
Purpose: Dosage has been identified as an important element of treatment that may affect treatment efficacy. The purpose of this study was to examine the role of dose schedule for treatment of grammatical morphology deficits in children with specific language impairment (SLI). Method: Sixteen 4-to-5-year-old children with SLI participated in a 5-week intervention consisting of equivalent daily Enhanced Conversational Recast treatment (Plante et al., 2014) targeting grammatical morphology...
October 1, 2016: Language, Speech, and Hearing Services in Schools
https://www.readbyqxmd.com/read/27668401/benefits-of-augmentative-signs-in-word-learning-evidence-from-children-who-are-deaf-hard-of-hearing-and-children-with-specific-language-impairment
#15
Lian van Berkel-van Hoof, Daan Hermans, Harry Knoors, Ludo Verhoeven
BACKGROUND: Augmentative signs may facilitate word learning in children with vocabulary difficulties, for example, children who are Deaf/Hard of Hearing (DHH) and children with Specific Language Impairment (SLI). Despite the fact that augmentative signs may aid second language learning in populations with a typical language development, empirical evidence in favor of this claim is lacking. AIMS: We aim to investigate whether augmentative signs facilitate word learning for DHH children, children with SLI, and typically developing (TD) children...
September 23, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27668399/the-management-of-cohesion-in-written-narratives-in-students-with-specific-language-impairment-differences-between-childhood-and-adolescence
#16
Monik Favart, Anna Potocki, Lucie Broc, Pauline Quémart, Josie Bernicot, Thierry Olive
The goal of this study was to investigate the management of cohesion by children and adolescents with specific language impairment (SLI) when writing a narrative in a communicative situation. Twelve children with SLI (from 7 to 11 years old) and 12 adolescents with SLI (from 12 to 18 years old) were chronological age-matched with 24 typically developing (TD) children and 24 TD adolescents. All participants attended mainstream classes: children in elementary schools and adolescents in middle and high schools...
September 23, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27643509/first-order-and-higher-order-sequence-learning-in-specific-language-impairment
#17
Gillian M Clark, Jarrad A G Lum
Objective: A core claim of the procedural deficit hypothesis of specific language impairment (SLI) is that the disorder is associated with poor implicit sequence learning. This study investigated whether implicit sequence learning problems in SLI are present for first-order conditional (FOC) and higher order conditional (HOC) sequences. Method: Twenty-five children with SLI and 27 age-matched, nonlanguage-impaired children completed 2 serial reaction time tasks. On 1 version, the sequence to be implicitly learnt comprised a FOC sequence and on the other a HOC sequence...
September 19, 2016: Neuropsychology
https://www.readbyqxmd.com/read/27636190/on-line-processing-and-comprehension-of-direct-object-pronoun-sentences-in-spanish-speaking-children-with-specific-language-impairment
#18
Dolors Girbau
Eleven native Spanish-speaking children with Specific Language Impairment (SLI) (8;3-10;11) and 11 typically developing children (8;7-10;8) received a comprehensive psycholinguistic evaluation. Participants listened to either Direct Object (DO) pronoun sentences or filler sentences without any pronoun, and they decided whether a picture on the screen (depicting the antecedent, another noun in the sentence, or an unrelated object) was 'alive'. They answered comprehension questions about pronoun sentences. Children with SLI showed significantly poorer comprehension of DO pronoun sentences when answering comprehension questions than children with Typical Language Development (TLD)...
September 16, 2016: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/27618388/examining-the-language-phenotype-in-children-with-typical-development-specific-language-impairment-and-fragile-x-syndrome
#19
Eileen Haebig, Audra Sterling, Jill Hoover
Purpose: One aspect of morphosyntax, finiteness marking, was compared in children with fragile X syndrome (FXS), specific language impairment (SLI), and typical development matched on mean length of utterance (MLU). Method: Nineteen children with typical development (mean age = 3.3 years), 20 children with SLI (mean age = 4.9 years), and 17 boys with FXS (mean age = 11.9 years) completed the Test of Early Grammatical Impairment (TEGI; Rice & Wexler, 2001), and other cognitive and language assessments...
September 8, 2016: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/27615432/memory-consolidation-in-children-with-specific-language-impairment-delayed-gains-and-susceptibility-to-interference-in-implicit-sequence-learning
#20
Lise Desmottes, Christelle Maillart, Thierry Meulemans
In this study, the time course of the procedural learning of a visuomotor sequence skill was followed over a 24-hour and a 1-week time period in children with and without specific language impairment (SLI). Two aspects of memory consolidation in implicit sequence learning were examined: the evolution of post-training gains in sequence knowledge (Experiment 1) and the susceptibility to interference (Experiment 2). In the first experiment, 18 children with SLI and 17 control children matched for sex, age, and nonverbal intelligence completed a serial reaction-time (SRT) task and were tested 24 hours and 1 week after practicing...
September 10, 2016: Journal of Clinical and Experimental Neuropsychology
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