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gynecomastia

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https://www.readbyqxmd.com/read/28926831/multiparameter-investigation-of-a-46-xx-46-xy-tetragametic-chimeric-phenotypical-male-patient-with-bilateral-scrotal-ovotestes-and-ovulatory-activity
#1
Yolande van Bever, Katja P Wolffenbuttel, Hennie T Brüggenwirth, Eric Blom, Annelies de Klein, Bert H J Eussen, Florijn van der Windt, Sabine E Hannema, Arianne B Dessens, Lambert C J Dorssers, Katharina Biermann, Remko Hersmus, Yolanda B de Rijke, Leendert H J Looijenga
We report on an adult male initially presenting with gynecomastia and a painless scrotal mass without additional genital anomalies. Hyperpigmentation of the skin following the Blaschko's lines was identified. He underwent gonadectomy because of suspected cancer. Histological analyses revealed an ovotestis with ovulatory activity confirmed by immunohistochemistry with multiple markers. Karyotyping of cultured peripheral blood lymphocytes and a buccal smear revealed a 46,XX/46,XY chimeric constitution with different percentages...
September 20, 2017: Sexual Development: Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
https://www.readbyqxmd.com/read/28899882/chromosome-15-structural-abnormalities-effect-on-igf1r-gene-expression-and-function
#2
Rossella Cannarella, Teresa Mattina, Rosita A Condorelli, Laura M Mongioì, Giuseppe Pandini, Sandro La Vignera, Aldo E Calogero
Insulin-like growth factor 1 receptor (IGF1R), mapping on the 15q26.3 chromosome, is required for normal embryonic and postnatal growth. The aim of the present study was to evaluate the IGF1R gene expression and function in three unrelated patients with chromosome 15 structural abnormalities. We report two male patients with the smallest 15q26.3 chromosome duplication described so far, and a female patient with ring chromosome 15 syndrome. Patient one, with a 568 kb pure duplication, had overgrowth, developmental delay, mental and psychomotor retardation, obesity, cryptorchidism, borderline low testis volume, severe oligoasthenoteratozoospermia and gynecomastia...
October 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28876553/the-circumareolar-approach-to-gynecomastia-and-transgender-surgery-modifications-to-provide-correct-nipple-areolar-complex-position-and-shape
#3
T Jay, K Segwapa
BACKGROUND: In surgery for gynaecomastia, excision with minimal scarring and correct position of the nipple areolar complex (NAC) are key to a successful outcome. We report on a pilot study on the use of a circumareolar excision and the use of mathematical vector calculation to position the NAC and execute surgery and report on the outcomes. METHOD: From 2014 to 2015, the authors operated on 9 gynecomastia or transgender patients. Based on research performed by Gertrude Beer, Beckenstein and Shulman we designed a mathematical modification of the technique described by Persichetti to provide correct NAC positioning as well as aesthetically pleasing NAC shape...
March 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876176/gynecomastia-histological-appearance-in-different-age-groups
#4
Alba Fricke, Gabriele M Lehner, G Björn Stark, Vincenzo Penna
OBJECTIVE: Gynecomastia is a common finding in the male population which is mostly idiopathic. The aim of our study was to analyze the histological differences in young and old patient groups and its association with recurrence rates. METHODS: Three hundred and five gynecomastia patients (555 breasts) undergoing surgical treatment from 1997 to 2015 were divided into four groups: Group 1: 13-17 years, Group 2: 18-30 years, Group 3: 31-49 years and Group 4: 50-83 years...
September 6, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28867562/long-term-anti-tumor-activity-and-safety-of-enzalutamide-monotherapy-in-hormone-na%C3%A3-ve-prostate-cancer-3-year-open-label-follow-up-results
#5
Bertrand Tombal, Michael Borre, Per Rathenborg, Patrick Werbrouck, Hendrik Van Poppel, Axel Heidenreich, Peter Iversen, Johan Braeckman, Jiri Heracek, Benoit Baron, Andrew Krivoshik, Mohammad Hirmand, Matthew R Smith
PURPOSE: A phase 2 study of enzalutamide monotherapy in patients with hormone-naïve prostate cancer demonstrated high prostate-specific antigen response rates at 25 weeks, 1 year and 2 years, with minimal effects on total body bone mineral density and favorable safety. This follow-up analysis evaluated enzalutamide's anti-tumor activity and safety at 3 years. MATERIALS AND METHODS: Sixty-seven patients with hormone-naïve prostate cancer and non-castrate testosterone (≥230 ng/dL) received enzalutamide 160 mg/day orally until disease progression or unacceptable toxicity in a single-arm analysis...
August 31, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28845839/management-of-adolescent-gynecomastia-an-update
#6
Ashraf T Soliman, Vincenzo De Sanctis, Mohamed Yassin
Gynecomastia refers to an enlargement of the male breast caused by benign proliferation of the glands ducts and stromal components including fat. It is the most common form of breast swelling seen in adolescent males. During pubertal development, gynecomastia can develop as a result of transient relative imbalances between androgens and estrogens. Pubertal gynecomastia is self-limited in 75 to 90% of adolescents and regresses over 1 to 3 years. However it may cause significant psychological stress and depression in adolescents...
August 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28842781/closed-suction-drains-after-subcutaneous-mastectomy-for-gynecomastia-do-they-reduce-complications
#7
Jerry W Chao, Janani A Raveendran, Connor Maly, Gary Rogers, Michael Boyajian, Albert K Oh
BACKGROUND: In cases of refractory gynecomastia, surgical excision of excess glandular breast tissue is often warranted. Closed-suction drain placement is commonplace; however, the effect of drains on preventing complications after male breast surgery has not been fully elucidated in the literature. OBJECTIVE: To investigate the effect of drains on reducing seroma and hematoma after subcutaneous mastectomy for gynecomastia. METHODS: Retrospective chart review of patients undergoing subcutaneous mastectomy for gynecomastia over a 10-year period...
August 25, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28828098/radiologic-presentation-of-a-myofibroblastoma-of-the-adult-male-breast
#8
Evan Rochlis, Pauline Germaine
We present the case of a 50-year-old male with bilateral gynecomastia who was incidentally found to have 0.8-cm subareolar mass on computed tomography. Mammographic and sonographic characteristics of the lesion are described as well as a brief historical review of myofibroblastoma, a rare mesenchymal tumor.
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28810998/delayed-diagnosis-of-acromegaly-in-the-context-of-post-traumatic-stress-disorder-due-to-symptoms-mimicking-known-psychotropic-medication-side-effects
#9
Ray-Bernard Portier, Afshin Afarin, Sara Pope
BACKGROUND: Acromegaly is caused by elevated secretion of human growth hormone, which is frequently because of intracranial tumors. This diagnosis is fairly uncommon with an incidence of 3 to 4 cases per million patients per year. We are presenting a case of acromegaly diagnosed in an active duty Chief Petty Officer. MATERIALS AND METHODS: A 38-year-old male Chief Petty Officer with no previous mental health diagnosis experienced post-traumatic stress disorder (PTSD)-like symptoms in early 2012 after deploying to Iraq and Afghanistan from 2010 to 2011...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28804590/feminizing-adrenocortical-carcinoma-without-gynecomastia
#10
Farida Chentli, Fadila Chabour, Djafer Bouchibane, Nouria Nouar
Malignant feminizing adrenocortical tumors are exceedingly rare. Their main presentation is gynecomastia. In these estrogen secreting tumors (with or without other adrenocortical hormones) lack of gynecomastia is exceptional as in our case. A 44-year-old man presented with abdominal pain. Radiological assessment revealed a tumor measuring 120 × 95 mm in the retroperitoneal area with numerous metastases. Pathological examination pleaded for an adrenal origin with a Weiss's score of 5. Six months later, the tumor relapsed, and he had a second surgery and was sent for hormone assessment...
July 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28795986/orange-peel-excision-of-gland-a-novel-surgical-technique-for-treatment-of-gynecomastia
#11
S S Shirol
No abstract text is available yet for this article.
September 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28795985/comment-to-orange-peel-excision-of-gland-a-novel-surgical-technique-for-treatment-of-gynecomastia
#12
Alessandro Innocenti, Francesco Ciancio, Domenico Parisi, Aurelio Portincasa, Dario Melita, Marco Innocenti
No abstract text is available yet for this article.
September 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28758536/gynecomastia-glandular-liposculpture-through-a-single-transaxillary-one-hole-incision
#13
Yung Ki Lee, Jun Hee Lee, Sang Yoon Kang
Gynecomastia is characterized by the benign proliferation of breast tissue in men. Herein, we present a new method for the treatment of gynecomastia, using ultrasound-assisted liposuction with both conventional and reverse-cutting edge tip cannulas in combination with a pull-through lipectomy technique with pituitary forceps through a single transaxillary incision. Thirty patients were treated with this technique at the author's institution from January 2010 to January 2015. Ten patients were treated with conventional surgical excision of the glandular/fibrous breast tissue combined with liposuction through a periareolar incision before January 2010...
July 30, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28742500/adverse-effects-of-androgen-deprivation-therapy-in-patients-with-prostate-cancer-focus-on-metabolic-complications
#14
REVIEW
Vasileios Tzortzis, Michael Samarinas, Ioannis Zachos, Athanasios Oeconomou, Louis L Pisters, Alexandra Bargiota
Prostate cancer is the most common cancer among men and androgen deprivation therapy (ADT) is the most effective treatment for this disease. The cornerstone of the treatment of prostate cancer is inhibition of testosterone production which interrupts testosterone-induced growth of the prostate tumor. The dramatic decrease in testosterone levels, however, has several undesirable effects on the metabolic profile and bone metabolism and can also lead to fatigue, loss of libido, gynecomastia, and anemia, provoke vasomotor flushing, and generally affect the quality of life...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28725962/optimal-positioning-of-the-nipple-areola-complex-in-men-using-the-mohrenheim-estimated-tangential-tracking-line-mett-line-an-intuitive-approach
#15
Tobias R Mett, Nicco Krezdorn, Rosalia Luketina, Maria K Boyce, Helga Henseler, Ramin Ipaktchi, Peter M Vogt
INTRODUCTION: The reconstruction of the body shape after post-bariatric surgery or high-grade gynecomastia involves, besides skin tightening, the repositioning of anatomical, apparent landmarks. The surgeon usually defines these during the preoperative planning. In particular, the positions of the nipple-areola complexes (NAC) should contribute to the gender-appropriate appearance. While in the female breast numerous methods have been developed to determine the optimal position of the NACs, there are only a few, metric and often impractical algorithms for positioning the nipples and areoles in the male...
July 19, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28716370/a-systematic-review-and-framework-for-the-use-of-hormone-therapy-with-salvage-radiation-therapy-for-recurrent-prostate-cancer
#16
REVIEW
Daniel E Spratt, Robert T Dess, Zachary S Zumsteg, Daniel W Lin, Phuoc T Tran, Todd M Morgan, Emmanuel S Antonarakis, Paul L Nguyen, Charles J Ryan, Howard M Sandler, Matthew R Cooperberg, Edwin Posadas, Felix Y Feng
CONTEXT: Salvage radiotherapy (SRT) is a standard of care for men who recur postprostatectomy, and recent randomized trials have assessed the benefit and toxicity of adding hormone therapy (HT) to SRT with differing results. OBJECTIVE: To perform a systematic review of randomized phase III trials of the use of SRT ± HT and generate a framework for the use of HT with SRT. EVIDENCE ACQUISITION: Systematic literature searches were conducted on February 15, 2017 in three databases (MEDLINE [via PubMed], EMBASE, and ClinicalTrials...
July 14, 2017: European Urology
https://www.readbyqxmd.com/read/28697008/reply-to-the-comment-on-management-of-gynecomastia-in-patients-with-different-body-types-considerations-on-312-consecutive-treated-cases
#17
Alessandro Innocenti, Dario Melita, Francesco Mori, Francesco Ciancio, Marco Innocenti
No abstract text is available yet for this article.
August 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28697007/management-of-gynecomastia-in-patients-with-different-body-types-considerations-on-312-consecutive-treated-cases
#18
Panxi Yu, Xiaonan Yang, Zuoliang Qi
No abstract text is available yet for this article.
August 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28682848/false-positive-uptake-in-bilateral-gynecomastia-on-68ga-psma-pet-ct-scan
#19
Arun Sasikumar, Ajith Joy, Bindu P Nair, M R A Pillai, Jayaprakash Madhavan
A 66-year-old man on hormonal therapy with prostate cancer was referred for Ga-PSMA PET/CT scan for biochemical recurrence. Ga-PSMA PET/CT scan detected moderate heterogeneous tracer concentration in bilateral breast parenchyma, in addition to the abnormal tracer concentration in enlarged prostate gland, right external iliac lymph node, and sclerotic lesion in L4 vertebra. On clinical examination, he was found to have bilateral gynecomastia. Abnormal concentration of Ga-PSMA in breast cancer is now well known, and in this context, it is important to know that tracer localization can occur in gynecomastia as well, as evidenced in this case...
September 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28680222/lymphomatous-involvement-of-male-breast-in-a-patient-with-bilateral-gynecomastia-demonstration-with-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#20
Punit Sharma
No abstract text is available yet for this article.
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
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