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Trigeminal nerve

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https://www.readbyqxmd.com/read/28812959/periocular-manifestations-of-trigeminal-trophic-syndrome-a-case-series-and-literature-review
#1
Katherine A McVeigh, Morag Adams, Richard Harrad, Rebecca Ford
Trigeminal trophic syndrome (TTS) is a condition whereby persistent facial ulceration presents consequent to central or peripheral insult to the trigeminal nerve. Lesions are created by repetitive self-inflicted manipulation and trauma of dysaesthetic skin within the trigeminal dermatome. We discuss four cases with aetiologies varied from presumed microvascular compromise to resection of cerebral meningioma, cerebrovascular accident, and herpes zoster ophthalmicus. We discuss the management of the under-recognised associated periocular skin ulcerations that result from physical manipulation of dysesthic skin and prove to be persistent and challenging to treat...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28807787/trigeminal-nerve-stimulation-induces-fos-immunoreactivity-in-selected-brain-regions-increases-hippocampal-cell-proliferation-and-reduces-seizure-severity-in-rats
#2
Beniamina Mercante, Paolo Enrico, Gabriele Floris, Marina Quartu, Marianna Boi, Maria Pina Serra, Paolo Follesa, Franca Deriu
Sites and mechanisms by which trigeminal nerve stimulation (TNS) exerts beneficial effects on symptoms of drug-resistant epilepsy and depression are still unknown. Effects of short-term TNS on brain regions involved in the physiopathology of these disorders were investigated in this study. Forty male rats were assigned to 3 groups: TNS (undergoing electrical stimulation of the left infraorbitary nerve via surgically implanted cuff electrodes); Sham (undergoing surgical procedure but without a stimulation); Naïve rats...
August 11, 2017: Neuroscience
https://www.readbyqxmd.com/read/28801514/bilateral-painful-tic-convulsif
#3
Valentina Fenech, Julian Cassar, Ludvic Zrinzo, Malcolm Vella
'Painful tic convulsif' (PTC) describes the coexistence of hemifacial spasm and trigeminal neuralgia. In this report, we describe a unique presentation of bilateral PTC in a man with bilateral hemifacial spasm and trigeminal neuralgia secondary to neurovascular conflict of all four cranial nerves. Following failed medical and radiofrequency therapy, microvascular decompression of three of the four involved nerves was performed, where the offending vessels were mobilised and Teflon used to prevent conflict recurrence...
August 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28799873/-birdlime-technique-using-tachosil-tissue-sealing-sheet-soaked-with-fibrin-glue-for-sutureless-vessel-transposition-in-microvascular-decompression-operative-technique-and-nuances
#4
Naoki Otani, Terushige Toyooka, Kazuya Fujii, Kosuke Kumagai, Satoru Takeuchi, Arata Tomiyama, Yasuaki Nakao, Takuji Yamamoto, Kojiro Wada, Kentaro Mori
OBJECTIVE Microvascular decompression (MVD) is effective for the treatment of trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia. The transposition technique is the standard procedure to avoid adhesions and granuloma around the decompression site but is more complex and difficult to perform than the interposition technique. The authors describe a simple and safe MVD transposition procedure they call the "birdlime" technique, which uses a tissue glue-coated collagen sponge soaked with fibrin glue, and the results of this technique...
August 11, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28798669/receptor-mechanisms-mediating-the-pro-nociceptive-action-of-hydrogen-sulfide-in-rat-trigeminal-neurons-and-meningeal-afferents
#5
Kseniya Koroleva, Alsu Mustafina, Aleksey Yakovlev, Anton Hermann, Rashid Giniatullin, Guzel Sitdikova
Hydrogen sulfide (H2S), a well-established member of the gasotransmitter family, is involved in a variety of physiological functions, including pro-nociceptive action in the sensory system. Although several reports have shown that H2S activates sensory neurons, the molecular targets of H2S action in trigeminal (TG) nociception, implicated in migraine, remains controversial. In this study, using suction electrode recordings, we investigate the effect of the H2S donor, sodium hydrosulfide (NaHS), on nociceptive firing in rat meningeal TG nerve fibers...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28777228/the-disputed-discovery-of-facial-and-trigeminal-nerve-function-revisiting-the-contributions-of-herbert-mayo-and-charles-bell
#6
Matthew L Carlson, James Bradley, Jamie J Van Gompel, R Shane Tubbs
BACKGROUND: The first description of the voluntary motor function of the facial nerve and separate sensory-motor contributions of the trigeminal nerve is most commonly attributed to Charles Bell. However, a review of the original scientific accounts and subsequent historical publications question the validity of this credit. The objective of the present historical analysis is to clarify the contributions of Herbert Mayo toward discovering the functions of the fifth and seventh cranial nerves and to raise awareness of this historical controversy within the medical literature...
August 2, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28776670/archosauriform-endocranial-morphology-and-osteological-evidence-for-semiaquatic-sensory-adaptations-in-phytosaurs
#7
Emily J Lessner, Michelle R Stocker
The examination of endocranial data of archosauriforms has led to advances on the evolution of body size, nerve pathways, and sensory abilities. However, much of that research has focused on bird-line archosaurs, resulting in a skewed view of Archosauria. Phytosauria, a hypothesized sister taxon to or early-branching member of Archosauria, provides a potential outgroup condition. Most previous phytosaur endocranial studies were executed without the use of modern technology and focused on derived members of Phytosauria...
August 4, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28772087/selective-percutaneous-controlled-radiofrequency-thermocoagulation-of-the-gasserian-ganglion-to-control-facial-pain-due-to-medication-related-osteonecrosis-of-the-jaw
#8
Ayano Taniguchi, Keita Fukazawa, Toyoshi Hosokawa
BACKGROUND: Medication-related osteonecrosis of the jaw (MRONJ) is an important complication in patients treated with antiresorptive agents such as bisphosphonates and the receptor activator of nuclear factor κB ligand inhibitor (denosumab). Treatment of MRONJ is extremely difficult, which makes it a distressing long-term complication. OBJECTIVES: We report a case of intractable facial pain due to MRONJ that was successfully controlled with selective percutaneous controlled radiofrequency thermocoagulation of the Gasserian ganglion...
August 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28765118/effects-of-electroacupuncture-to-the-trigeminal-nerve-area-on-the-autonomic-nervous-system-and-cerebral-blood-flow-in-the-prefrontal-cortex
#9
Hideaki Waki, Takuya Suzuki, Yuki Tanaka, Hideaki Tamai, Yoichi Minakawa, Shogo Miyazaki, Naruto Yoshida, Kazuo Uebaba, Kenji Imai, Tatsuya Hisajima
BACKGROUND: The autonomic nervous system and trigeminal nerve are involved in adjusting flow through diverging cerebral arteries in the prefrontal cortex. The purpose of this study was to examine the effect of 100 Hz electroacupuncture (EA) to the trigeminal nerve area on cerebral blood flow and autonomic nervous system function. METHOD: This was a randomised crossover study of 16 healthy volunteers who were assigned to an EA or control group. Stimulation (in the EA group) was performed five times, each after 1 min of rest...
August 1, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/28761141/effects-of-pulpotomy-using-mineral-trioxide-aggregate-on-prostaglandin-transporter-and-receptors-in-rat-molars
#10
Naoto Ohkura, Naoki Edanami, Ryosuke Takeuchi, Aiko Tohma, Mariko Ohkura, Nagako Yoshiba, Kunihiko Yoshiba, Hiroko Ida-Yonemochi, Hayato Ohshima, Takashi Okiji, Yuichiro Noiri
Mineral trioxide aggregate (MTA) is a commonly used dental pulp-capping material with known effects in promoting reparative dentinogenesis. However, the mechanism by which MTA induces dentine repair remains unclear. The aim of the present study was to investigate the role of prostaglandin E2 (PGE2) in dentine repair by examining the localisation and mRNA expression levels of its transporter (Pgt) and two of its receptors (Ep2 and Ep4) in a rat model of pulpotomy with MTA capping. Ep2 expression was detected in odontoblasts, endothelial cells, and nerve fibres in normal and pulpotomised tissues, whereas Pgt and Ep4 were immunolocalised only in the odontoblasts...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28758278/clinical-and-imaging-findings-treatments-and-outcomes-in-27-dogs-with-imaging-diagnosed-trigeminal-nerve-sheath-tumors-a-multi-center-study
#11
Katie E Swift, Stephanie McGrath, Michael W Nolan, Martin Young, Michael Reese, Sangeeta Rao, Elissa Randall, Del Leary, Susan LaRue
The clinical behavior of canine trigeminal nerve sheath tumors and benefits of previously reported treatments are incompletely defined. Aims of this retrospective, multicenter, observational study were to describe clinical signs, tumor localization characteristics, treatments, and clinical outcomes in a group of dogs with this neoplasm. Databases at four hospitals were reviewed for dogs with a trigeminal nerve sheath tumor diagnosis, magnetic resonance imaging (MRI) studies, and presentation between 2004 and 2014...
July 31, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28757255/enhancement-of-nose-to-brain-delivery-of-hydrophilic-macromolecules-with-stearate-or-polyethylene-glycol-modified-arginine-rich-peptide
#12
Takanori Kanazawa, Mami Kaneko, Takaki Niide, Fuminari Akiyama, Shino Kakizaki, Hisako Ibaraki, Shunsuke Shiraishi, Yuuki Takashima, Toyofumi Suzuki, Yasuo Seta
Recently, nose-to-brain delivery is a highly versatile route, which, in combination with novel drugs being developed for treating intractable CNS diseases, is a promising approach for the treatment of disorders. Furthermore, nano-sized drug carriers may improve nose-to-brain drug delivery by their capability to increase the transmucosal penetration of the drugs across nasal mucosal tissue barrier. However, there is still not enough information regarding mechanism of absorption pathway from nasal cavity to brain using nanocarriers...
July 27, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28754973/neuroprotective-effects-of-trigeminal-nerve-stimulation-in-severe-traumatic-brain-injury
#13
Amrit Chiluwal, Raj K Narayan, Wayne Chaung, Neal Mehan, Ping Wang, Chad E Bouton, Eugene V Golanov, Chunyan Li
Following traumatic brain injury (TBI), ischemia and hypoxia play a major role in further worsening of the damage, a process referred to as 'secondary injury'. Protecting neurons from causative factors of secondary injury has been the guiding principle of modern TBI management. Stimulation of trigeminal nerve induces pressor response and improves cerebral blood flow (CBF) by activating the rostral ventrolateral medulla. Moreover, it causes cerebrovasodilation through the trigemino-cerebrovascular system and trigemino-parasympathetic reflex...
July 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28751945/injured-anterior-superior-alveolar-nerve-endoscopically-resected-within-maxillary-sinus
#14
Amir H Dorafshar, A Lee Dellon, Eric Lee Wan, Sashank Reddy, Victor W Wong
Posttraumatic facial pain is due to an injured nerve, most often a branch of the trigeminal nerve. While surgical approaches to injuries of the supraorbital, supratrochlear, infraorbital, and inferior alveolar nerves have been reported, an injury to the anterior superior alveolar nerve (ASAN) has not been reported. An algorithm is proposed for the diagnosis of injury to the ASAN versus the infraorbital nerve itself. A case is reported in which pain relief was achieved by dividing the ASAN within the maxillary sinus, leaving the proximal end exposed within the sinus at the level of the orbital floor...
September 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28748271/the-emerging-role-of-gamma-knife-radiosurgery-in-the-management-of-glossopharyngeal-neuralgia
#15
REVIEW
Alfio Spina, Nicola Boari, Filippo Gagliardi, Michele Bailo, Carlotta Morselli, Sandro Iannaccone, Pietro Mortini
Glossopharyngeal neuralgia (GPN) represents a rare craniofacial disorder accounting for about 1% of all craniofacial pain syndromes. GPN shares several pathophysiologic and clinical features with the more common trigeminal neuralgia. Medical therapy and microvascular decompression, in case of vascular nerve compression, represented the mainstay of GPN management. Other ablative therapies have been reported to date; however, few data are available because of the rarity of this pain syndrome. Among the ablative procedures, gamma knife radiosurgery (GKRS) has been recently introduced in the management of GPN with good pain control and low complication rates...
July 26, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28745006/nevus-of-ota-oculodermal-melanocytosis-in-a-dog
#16
Pedro Malho, Anita Shea, David Donaldson
A 5-year-old, female, spayed Rhodesian Ridgeback presented with ocular melanocytosis and skin hyperpigmentation involving the distribution of the first and second divisions of the trigeminal nerve on the right side of the face. The dermatomal pattern of the hyperpigmentation was similar to nevus of Ota or oculodermal melanocytosis reported in humans. This condition has been associated with increased risk of developing secondary glaucoma and melanoma transformation in skin, ocular, orbital tissues, and the central nervous system...
July 25, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28739568/posterior-meningeal-artery-dmso-injection-resulting-in-reproducible-asystole-prior-to-onyx-therapy-of-a-dural-arteriovenous-fistula-a-previously-undescribed-variant-of-the-trigeminocardiac-reflex-or-a-new-phenomenon
#17
Matthew Thomas Crockett, Anthony Ernest Robinson, Harmeet Aneja, Timothy John Phillips
We describe a case of reproducible asystole during endovascular treatment of a posterior fossa dural arteriovenous fistula. Catheterisation of the posterior meningeal artery, a branch of the vertebral artery in this patient, followed by dimethyl sulfoxide injection prior to Onyx administration resulted in two episodes of asystole.To the best of our knowledge, this is the first reported case of asystole occurring during endovascular intervention in the posterior meningeal artery. This may represent a previously undescribed variant of the trigemino-cardiac reflex (TGCR) caused by chemical stimulation of small areas of trigeminally innervated posterior fossa dura...
July 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28739515/the-trigeminocardiac-reflex-during-the-anterior-transpetrosal-approach
#18
Shunsuke Shibao, Karam Kenawy, Hamid Borghei-Razavi, Kazunari Yoshida
OBJECTIVE: The anterior transpetrosal approach (ATPA), during which the trigeminal nerve (TN) is manipulated, has a risk of eliciting the trigeminocardiac reflex (TCR). The aim of this study was to assess the risk of TCR during ATPA. METHODS: Surgical records of 92 patients who had surgical treatment via ATPA at the Keio University Hospital between December 2005 and June 2015 were retrospectively analyzed. Patients were divided into 2 groups on the basis of the occurrence of TCR during surgery, and clinical and tumor characteristics were compared...
July 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28736339/tfos-dews-ii-pain-and-sensation-report
#19
REVIEW
Carlos Belmonte, Jason J Nichols, Stephanie M Cox, James A Brock, Carolyn G Begley, David A Bereiter, Darlene A Dartt, Anat Galor, Pedram Hamrah, Jason J Ivanusic, Deborah S Jacobs, Nancy A McNamara, Mark I Rosenblatt, Fiona Stapleton, James S Wolffsohn
Pain associated to mechanical and chemical irritation of the eye surface is mediated by trigeminal ganglia mechano- and polymodal nociceptor neurons while cold thermoreceptors detect wetness and reflexly maintain basal tear production and blinking rate. These neurons project into two regions of the trigeminal brain stem nuclear complex: ViVc, activated by changes in the moisture of the ocular surface and VcC1, mediating sensory-discriminative aspects of ocular pain and reflex blinking. ViVc ocular neurons project to brain regions that control lacrimation and spontaneous blinking and to the sensory thalamus...
May 4, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28736325/traumatic-neuropathy-of-the-trigeminal-nerve-in-a-college-trumpet-player-a-case-report
#20
Jeremy Lee Stanek, Kevin Donserm Komes
A 20-year-old college trumpet player presented with a 3-month history of upper lip numbness and worsening playing ability after a marching band performance. Examination demonstrated anesthesia of the upper lip that followed the borders of the trumpet mouthpiece. While playing, the patient had poor range and an airy tone quality. A prescription of complete embouchure rest for 6 weeks and a tailored return to play regimen resulted in resolution of upper lip numbness and improved trumpet playing. Neuropathy of the lip in a brass player is uncommon but highlights the uniqueness of injuries that may be sustained by performing artists...
July 20, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
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