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https://www.readbyqxmd.com/read/28342508/gender-smoking-body-size-and-aneurysm-geometry-influence-the-biomechanical-rupture-risk-of-abdominal-aortic-aneurysms-as-estimated-by-finite-element-analysis
#1
Moritz Lindquist Liljeqvist, Rebecka Hultgren, Antti Siika, T Christian Gasser, Joy Roy
OBJECTIVE: Finite element analysis (FEA) has been suggested to be superior to maximal diameter measurements in predicting rupture of abdominal aortic aneurysms (AAAs). Our objective was to investigate to what extent previously described rupture risk factors were associated with FEA-estimated rupture risk. METHODS: One hundred forty-six patients with an asymptomatic AAA of a 40- to 60-mm diameter were retrospectively identified and consecutively included. The patients' computed tomography angiograms were analyzed by FEA without (neutral) and with (specific) input of patient-specific mean arterial pressure (MAP), gender, family history, and age...
April 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28341899/cortical-microstructure-compensates-for-smaller-bone-size-in-young-caribbean-hispanic-versus-non-hispanic-white-men
#2
M D Walker, A Kepley, K Nishiyama, B Zhou, E Guo, T L Nickolas
Hispanic men have smaller bone size but thicker and denser cortices compared to white men, leading to similar mechanical competence. INTRODUCTION: The purpose of this study was to assess differences in vBMD and microarchitecture in young Caribbean Hispanic (n = 30) and non-Hispanic Caucasian (n = 30) men. METHODS: We measured areal bone mineral density (aBMD) at the spine, total hip (TH), femoral neck (FN), and forearm by dual-energy X-ray absorptiometry (DXA) and bone geometry, mass, microarchitecture, and mechanical competence by high-resolution peripheral quantitative computed tomography (HRpQCT), individual trabecula segmentation (ITS), and finite element analysis (FEA)...
March 24, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28333370/influence-of-nickel-titanium-rotary-systems-with-varying-tapers-on-the-biomechanical-behaviour-of-maxillary-first-premolars-under-occlusal-forces-a-finite-element-analysis-study
#3
S Askerbeyli Ors, A Serper
AIM: To evaluate the effect of three nickel-titanium (Ni-Ti) rotary systems with varying tapers on stress distribution and to analyse potential fracture patterns as well as the volume of fracture-susceptible regions in two-rooted maxillary premolars. METHODOLOGY: The root canals of three single-rooted premolars were prepared with either HeroShaper (Micro-Mega, Besançon, France) to (size 30, .04 taper), Revo-S (Micro-Mega) to AS30 (size 30, .06 taper) or ProTaper Universal (Dentsply Maillefer, Ballaigeus, Switzerland) to F3 (size 30, ...
March 23, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28332735/non-hodgkin-lymphoma-in-south-east-asia-an-analysis-of-the-histopathology-clinical-features-and-survival-from-thailand
#4
Tanin Intragumtornchai, Udomsak Bunworasate, Kitsada Wudhikarn, Arnuparp Lekhakula, Jakrawadi Julamanee, Kanchana Chansung, Chittima Sirijerachai, Lalita Norasetthada, Weerasak Nawarawong, Archrob Khuhapinant, Noppadol Siritanaratanakul, Tontanai Numbenjapon, Kannadit Prayongratana, Suporn Chuncharunee, Pimjai Niparuck, Tawatchai Suwanban, Nongluk Kanitsap, Somchai Wongkhantee, Rutchanid Pornvipavee, Peerapon Wong, Nisa Makruasi, Pongsak Wannakrairot, Thamathorn Assanasen, Sanya Sukpanichnant, Paisarn Boonsakan, Wasana Kanoksil, Charin Ya-In, Kanita Kayasut, Winyu Mitranun, Naree Warnnissorn
Systemic reports on the descriptive epidemiology of non-Hodgkin lymphoma (NHL) from Southeast Asia are scarce. A nationwide multi-institutional registry was conducted to compare the histopathology, clinical features, and survival of Thai adult patients with NHL using large registries, especially those from Far East Asia (FEA). Using a web-based registry system, 13 major medical centers from the 4 geographic regions of Thailand prospectively collected, from 2007 to 2014, the diagnostic pathology, according to the World Health Organization classification, 2008, clinical features and survival of 4056 patients who were newly diagnosed with NHL...
March 23, 2017: Hematological Oncology
https://www.readbyqxmd.com/read/28324958/ultrafast-oscillatory-flow-pcr-for-amplication-of-urine-short-tandem-repeats
#5
Haoyu Tang, Tao Dong
The short tandem repeats (STRs) in human urine which is the most sensitive body fluid can be serviced as biomarkers for the individual identification. PCR microchips are automated, sensitive and rapid. In this report, COMSOL with Finite Element Analysis (FEA) is employed to study the temperature distribution of the base layer to optimize the structure of the microfluidic chip. Meanwhile, the oscillatory PCR microdevice is preliminary tested by DNA samples extracted from urine with the FTA papers and CSF1PO, TPOX, TH01 Multiplex kits...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28303730/biomechanical-properties-of-the-pelvic-floor-muscles-of-continent-and-incontinent-women-using-an-inverse-finite-element-analysis
#6
M E T Silva, S Brandão, M P L Parente, T Mascarenhas, R M Natal Jorge
Pelvic disorders can be associated with changes in the biomechanical properties in the muscle, ligaments and/or connective tissue form fascia and ligaments. In this sense, the study of their mechanical behavior is important to understand the structure and function of these biological soft tissues. The aim of this study was to establish the biomechanical properties of the pelvic floor muscles of continent and incontinent women, using an inverse finite element analysis (FEA). The numerical models, including the pubovisceral muscle and pelvic bones were built from magnetic resonance (MR) images acquired at rest...
March 17, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28289315/wrinkling-of-tympanic-membrane-under-unbalanced-pressure
#7
Bo Wang, Pravarsha Ghanta, Sandra Vinnikova, Siyuan Bao, Junfeng Liang, Hongbing Lu, Shuodao Wang
Mechanics of tympanic membrane (TM) is crucial for investigating the acoustic transmission through the ear. In this study, we studied the wrinkling behavior of tympanic membrane when it is exposed to mismatched air pressure between the ambient and the middle ear. The Rayleigh-Ritz method is adopted to analyze the critical wrinkling pressure and the fundamental eigenmode. An approximate analytical solution is obtained and validated by finite element analysis (FEA). The model will be useful in future investigations on how the wrinkling deformation of the TM alters the acoustic transmission function of the ear...
April 2017: Journal of Applied Mechanics
https://www.readbyqxmd.com/read/28285881/finite-element-analysis-of-the-amputated-lower-limb-a-systematic-review-and-recommendations
#8
REVIEW
A S Dickinson, J W Steer, P R Worsley
The care and rehabilitation of individuals after lower limb amputation presents a substantial and growing socioeconomic challenge. Clinical outcome is closely linked to successful functional rehabilitation with a prosthetic limb, which depends upon comfortable prosthetic limb - residual limb load transfer. Despite early interest in the 1980s, the amputated limb has received considerably less attention in computational biomechanical analysis than other subjects, such as arthroplasty. This systematic literature review investigates the state of the art in residual limb finite element analysis published since 2000...
March 9, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28283828/risk-factors-and-peripartum-outcomes-of-failed-epidural-a-prospective-cohort-study
#9
Carmen Bucstain, Gali Garmi, Noah Zafran, Sivan Zuarez-Easton, Julia Carmeli, Raed Salim
PURPOSE: Awareness to rate, risk factors, and the associated peripartum outcomes of failed epidural analgesia (FEA) may improve expectations and labor management. We aimed to identify risk factors for FEA and to examine peripartum outcomes associated with failure. METHODS: A prospective cohort study conducted between March 2015 and August 2015, at a single university medical center. Laboring women at ≥34 weeks, receiving epidural analgesia, were eligible. Pain was evaluated using a 0-10 cm visual analogue scale (VAS)...
March 10, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28282590/correlation-between-transversal-and-orthogonal-maximal-diameters-of-abdominal-aortic-aneurysms-and-alternative-rupture-risk-predictors
#10
Kamil Novak, Stanislav Polzer, Tomas Krivka, Robert Vlachovsky, Robert Staffa, Lubos Kubicek, Lukas Lambert, Jiri Bursa
PURPOSE: There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment...
March 6, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28279427/finite-element-analysis-of-the-three-different-posterior-malleolus-fixation-strategies-in-relation-to-different-fracture-sizes
#11
Adeel Anwar, Decheng Lv, Zhi Zhao, Zhen Zhang, Ming Lu, Muhammad Umar Nazir, Wasim Qasim
PURPOSE: Appropriate fixation method for the posterior malleolar fractures (PMF) according to the fracture size is still not clear. Aim of this study was to evaluate the outcomes of the different fixation methods used for fixation of PMF by finite element analysis (FEA) and to compare the effect of fixation constructs on the size of the fracture computationally. MATERIALS AND METHODS: Three dimensional model of the tibia was reconstructed from computed tomography (CT) images...
February 20, 2017: Injury
https://www.readbyqxmd.com/read/28269415/evaluating-the-deflection-of-dexterous-continuum-manipulators-with-unevenly-distributed-compliant-joints
#12
Anzhu Gao, Ryan J Murphy, Hao Liu, Iulian Iordachita, Mehran Armand
Dexterous continuum manipulators (DCMs) offer great potential for increasing instrument reach in minimally-invasive surgical procedures. We previously designed and fabricated a tendon driven DCM with a large instrument channel and evenly distributed compliant joints for minimally-invasive skull base surgery and the treatment of osteolysis during hip revision surgery. The evenly distributed compliant joints, in some cases, may limit the reach of the DCM during lesion removal. In this paper, we propose a finite element analysis (FEA) method for optimizing the distribution of the compliant joints based on treatment space requirements determined preoperatively...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269305/biologically-inspired-multi-layered-synthetic-skin-for-tactile-feedback-in-prosthetic-limbs
#13
Luke Osborn, Harrison Nguyen, Joseph Betthauser, Rahul Kaliki, Nitish Thakor
The human body offers a template for many state-of-the-art prosthetic devices and sensors. In this work, we present a novel, sensorized synthetic skin that mimics the natural multi-layered nature of mechanoreceptors found in healthy glabrous skin to provide tactile information. The multi-layered sensor is made up of flexible piezoresistive textiles that act as force sensitive resistors (FSRs) to convey tactile information, which are embedded within a silicone rubber to resemble the compliant nature of human skin...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268867/fea-modeling-and-fluid-flow-simulation-of-human-rectum-with-inserted-bowel-catheters
#14
Yong Zhang, Tina VanRiper, Brian Rague, Drew Weidman
In this project, fluid flow and fluid-structure interaction are studied for the human lower gastrointestinal (GI) region. The study consists of two steps. First, we apply meshing methods to discretize both the human lower GI model and the catheter model at sufficient resolution suitable for importing into a Finite Element Analysis (FEA) tool. For model discretization, 3D models of the colon reconstructed from human MRI slices are used to obtain the valid inlet and outlet boundary surfaces. To resolve the viscous boundary layer in flow studies, a special structure of the near-wall volumetric mesh is built by triangular prisms that construct quasi-structured, multiple near-boundary sub-layers...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268767/stability-of-the-permanently-bent-plates-used-in-mandibular-reconstructive-surgery
#15
Si-Myung Park, Deukhee Lee, Jung-Woo Lee, Youngjun Kim, Laehyun Kim, Gunwoo Noh
In mandibular reconstructive surgery, straight surgical plates are predominantly used for osteotomy. In this process, a straight plate is bent to fit to the shape of the patient's defect. This potentially compromises the stability of the plate because of changes in mechanical properties resulting from plastic deformation; however, the effect of plastic deformation on stability has yet been investigated. In this study, we assess the stability of three types of commonly used bent plates for two types of mandible defect cases, using three-dimensional finite element analysis (FEA)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268766/an-investigation-of-animal-and-human-bones-for-predicting-probable-location-of-fractures
#16
Irfan Manarvi
Predicting location of fracture in animal and human bones has been a keen area of research for the past few decades. It has been established that it is various types of stress that results into bone failure. Past studies were mostly based on experimental testing of variety of bones with limited accuracy equipment leading to experimental errors. An effort has been made in present research to use latest experimental testing equipment in parallel with some modern techniques and tools such as 3D scanners for creating computer models and Finite Element Analysis (FEA) to conduct structural analysis that could allow unlimited changes in boundary conditions expected to be faced by a bone...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28259612/the-effect-of-boundary-constraints-on-finite-element-modelling-of-the-human-pelvis
#17
Peter J Watson, Ali Dostanpor, Michael J Fagan, Catherine A Dobson
The use of finite element analysis (FEA) to investigate the biomechanics of anatomical systems critically relies on the specification of physiologically representative boundary conditions. The biomechanics of the pelvis has been the specific focus of a number of FEA studies previously, but it is also a key aspect in other investigations of, for example, the hip joint or new design of hip prostheses. In those studies, the pelvis has been modelled in a number of ways with a variety of boundary conditions, ranging from a model of the whole pelvic girdle including soft tissue attachments to a model of an isolated hemi-pelvis...
March 1, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28244433/establishment-of-new-design-criteria-for-glidcop-%C3%A2-x-ray-absorbers
#18
Jeff T Collins, Jeremy Nudell, Gary Navrotski, Zunping Liu, Patric Den Hartog
An engineering research program has been conducted at the Advanced Photon Source (APS) in order to determine the thermomechanical conditions that lead to crack formation in GlidCop(®), a material commonly used to fabricate X-ray absorbers at X-ray synchrotron facilities. This dispersion-strengthened copper alloy is a proprietary material and detailed technical data of interest to the synchrotron community is limited. The results from the research program have allowed new design criteria to be established for GlidCop(®) X-ray absorbers based upon the thermomechanically induced fatigue behavior of the material...
March 1, 2017: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/28239606/influence-of-additive-manufactured-scaffold-architecture-on-the-distribution-of-surface-strains-and-fluid-flow-shear-stresses-and-expected-osteochondral-cell-differentiation
#19
Wim J Hendrikson, Anthony J Deegan, Ying Yang, Clemens A van Blitterswijk, Nico Verdonschot, Lorenzo Moroni, Jeroen Rouwkema
Scaffolds for regenerative medicine applications should instruct cells with the appropriate signals, including biophysical stimuli such as stress and strain, to form the desired tissue. Apart from that, scaffolds, especially for load-bearing applications, should be capable of providing mechanical stability. Since both scaffold strength and stress-strain distributions throughout the scaffold depend on the scaffold's internal architecture, it is important to understand how changes in architecture influence these parameters...
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/28227658/evaluating-the-deflection-of-dexterous-continuum-manipulators-with-unevenly-distributed-compliant-joints
#20
Anzhu Gao, Ryan J Murphy, Hao Liu, Iulian Iordachita, Mehran Armand, Anzhu Gao, Ryan J Murphy, Hao Liu, Iulian Iordachita, Mehran Armand, Hao Liu, Anzhu Gao, Iulian Iordachita, Mehran Armand, Ryan J Murphy
Dexterous continuum manipulators (DCMs) offer great potential for increasing instrument reach in minimally-invasive surgical procedures. We previously designed and fabricated a tendon driven DCM with a large instrument channel and evenly distributed compliant joints for minimally-invasive skull base surgery and the treatment of osteolysis during hip revision surgery. The evenly distributed compliant joints, in some cases, may limit the reach of the DCM during lesion removal. In this paper, we propose a finite element analysis (FEA) method for optimizing the distribution of the compliant joints based on treatment space requirements determined preoperatively...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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