keyword
MENU ▼
Read by QxMD icon Read
search

Diagnostics

keyword
https://www.readbyqxmd.com/read/28655215/development-of-a-new-method-based-on-unmodified-gold-nanoparticles-and-peptide-nucleic-acids-for-detecting-bovine-viral-diarrhea-virus-rna
#1
Maryam Askaravi, Seyedeh Elham Rezatofighi, Saadat Rastegarzadeh, Masoud Reza Seifi Abad Shapouri
A simple colorimetric assay is presented for detecting bovine viral diarrhea virus (BVDV)-RNA based on aggregation of gold nanoparticles (AuNPs) in the presence of charge-neutral peptide nucleic acids (PNA). Free charge-neutral PNA oligomers tended to be adsorbed onto AuNPs and act as a coagulant, whereas hybridizing complementary RNA with PNA disrupted PNA-induced AuNP aggregation, and the NPs remained stable. However, non-complementary RNA did not have this effect, and PNA induced aggregation of the AuNPs that resulted in a color change of the reaction from red to blue...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28655144/up-regulation-of-carcinoembryonic-antigen-related-cell-adhesion-molecule-1-in-gastrointestinal-cancer-and-its-clinical-relevance
#2
Muqing Zhou, Zhiming Jin, Yiwen Liu, Yiqing He, Yan Du, Cuixia Yang, Yingzhi Wang, Jiajie Hu, Lian Cui, Feng Gao, Manlin Cao
Serum carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is dysregulated in various malignant tumors and has been associated with tumor progression. However, the expression and regulatory mechanisms of serum CEACAM1 in gastrointestinal cancer are still unclear. The expression ratio of the CEACAM1-L and CEACAM1-S isoforms has seldom been investigated in gastrointestinal cancer. In this study, we intended to explore the expression and diagnostic value of CEACAM1 in gastrointestinal cancer. Serum CEACAM1 levels were measured by enzyme-linked immunosorbent assay...
June 24, 2017: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/28655082/-impact-of-the-2016-new-definition-and-classification-system-of-pancreatic-fistula-on-the-evaluation-of-pancreatic-fistula-after-pancreatic-surgery
#3
X L Han, J Xu, W M Wu, M H Dai, T P Zhang, Q Liao, G Chen, J C Guo, W B Wang, L Cong, Y P Zhao
Objective: To discuss the impact of updated definition and classification system of pancreatic fistula published in 2016 on the postoperative classification of pancreatic fistula. Methods: Retrospective analysis was made on patients who underwent pancreatic surgery at ward 1 in Department of General Surgery, Peking Union Medical College Hospital from January 2015 to December 2016.A total of 408 patients were included in this retrospective study, male/female was 184/224, aged from 9 to 81 years with mean age of 51...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28654989/risk-of-primary-tumor-sidedness-as-a-criterion-for-screening-diagnostic-colonoscopy-and-surveillance-intervals-reply
#4
Gianluca Tomasello, Fausto Petrelli, Sandro Barni
No abstract text is available yet for this article.
June 22, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28654946/fricative-contrast-and-coarticulation-in-children-with-and-without-speech-sound-disorders
#5
Edwin Maas, Marja-Liisa Mailend
Purpose: The purpose of this study was, first, to expand our understanding of typical speech development regarding segmental contrast and anticipatory coarticulation, and second, to explore the potential diagnostic utility of acoustic measures of fricative contrast and anticipatory coarticulation in children with speech sound disorders (SSD). Method: In a cross-sectional design, 10 adults, 17 typically developing children, and 11 children with SSD repeated carrier phrases with novel words with fricatives (/s/, /ʃ/)...
June 22, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28654944/perceptually-salient-sound-distortions-and-apraxia-of-speech-a-performance-continuum
#6
Katarina L Haley, Adam Jacks, Jessica D Richardson, Julie L Wambaugh
Purpose: We sought to characterize articulatory distortions in apraxia of speech and aphasia with phonemic paraphasia and to evaluate the diagnostic validity of error frequency of distortion and distorted substitution in differentiating between these disorders. Method: Study participants were 66 people with speech sound production difficulties after left-hemisphere stroke or trauma. They were divided into 2 groups on the basis of word syllable duration, which served as an external criterion for speaking rate in multisyllabic words and an index of likely speech diagnosis...
June 22, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28654937/handheld-in-vivo-reflectance-confocal-microscopy-for-the-diagnosis-of-eyelid-margin-and-conjunctival-tumors
#7
Elisa Cinotti, Aurélie Singer, Bruno Labeille, Damien Grivet, Pietro Rubegni, Catherine Douchet, Frédéric Cambazard, Gilles Thuret, Philippe Gain, Jean Luc Perrot
Importance: The clinical diagnosis of conjunctival and eyelid margin tumors is challenging, and new noninvasive imaging techniques could be valuable in this field. Objective: To assess the diagnostic accuracy of handheld in vivo reflectance confocal microscopy (IVCM) for the diagnosis of eyelid margin and conjunctival tumors. Design: A prospective observational study was conducted at University Hospital of Saint-Etienne from January 2, 2011, to December 31, 2016 (inclusion of patients until December 31, 2015, and follow-up until December 31, 2016)...
June 22, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28654934/risk-of-primary-tumor-sidedness-as-a-criterion-for-screening-diagnostic-colonoscopy-and-surveillance-intervals
#8
Martin C S Wong, John C T Wong
No abstract text is available yet for this article.
June 22, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28654920/greater-real-life-diagnostic-efficacy-of-allergen-molecule-based-diagnosis-for-prescription-of-immunotherapy-in-an-area-with-multiple-pollen-exposure
#9
Ulbosin Saltabayeva, Viktoriya Garib, Marina Morenko, Rafail Rosenson, Zhanat Ispayeva, Madina Gatauova, Loreta Zulus, Aleksandr Karaulov, Felix Gastager, Rudolf Valenta
BACKGROUND: Allergen molecule-based diagnosis has been suggested to facilitate the identification of disease-causing allergen sources and the prescription of allergen-specific immunotherapy (AIT). The aim of the current study was to compare allergen molecule-based IgE serology with allergen extract-based skin testing for the identification of the disease-causing allergen sources. The study was conducted in an area where patients are exposed to pollen from multiple sources (trees, grasses, and weeds) at the same time to compare the diagnostic efficiency of the 2 forms of diagnosis...
June 28, 2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28654912/identification-of-dysregulated-long-non-coding-rnas-micrornas-mrnas-in-tnm-i-stage-lung-adenocarcinoma
#10
Ziqiang Tian, Shiwang Wen, Yuefeng Zhang, Xinqiang Shi, Yonggang Zhu, Yanzhao Xu, Huilai Lv, Guiying Wang
Lung adenocarcinoma (LUAD) is the primary subtype in lung cancer, which is the leading cause of cancer-related death worldwide. This study aimed to investigate the aberrant expression profiling of long non-coding RNA (lncRNA) in TNM I stage (stage I) LUAD. The lncRNA/mRNA/miRNA expression profiling of stage I LUAD and adjacent non-tumor tissues from 4 patients were measured by RNA-sequencing. Total of 175 differentially expressed lncRNAs (DELs), 1321 differentially expressed mRNAs (DEMs) and 94 differentially expressed microRNAs (DEMIs) were identified in stage I LUAD...
June 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28654886/bimetallic-pt-au-nanocatalysts-electrochemically-deposited-on-boron-doped-diamond-electrodes-for-nonenzymatic-glucose-detection
#11
Siriwan Nantaphol, Takeshi Watanabe, Naohiro Nomura, Weena Siangproh, Orawon Chailapakul, Yasuaki Einaga
The enormous demand for medical diagnostics has encouraged the fabrication of high- performance sensing platforms for the detection of glucose. Nonenzymatic glucose sensors are coming ever closer to being used in practical applications. Bimetallic catalysts have been shown to be superior to single metal catalysts in that they have greater activity and selectivity. Here, we demonstrate the preparation, characterization, and electrocatalytic characteristics of a new bimetallic Pt/Au nanocatalyst. This nanocatalyst can easily be synthesized by electrodeposition by sequentially depositing Au and Pt on the surface of a boron-doped diamond (BDD) electrode...
June 17, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28654884/specific-and-selective-probes-for-staphylococcus-aureus-from-phage-displayed-random-peptide-libraries
#12
Laura M De Plano, Santina Carnazza, Grazia M L Messina, Maria Giovanna Rizzo, Giovanni Marletta, Salvatore P P Guglielmino
Staphylococcus aureus is a major human pathogen causing health care-associated and community-associated infections. Early diagnosis is essential to prevent disease progression and to reduce complications that can be serious. In this study, we selected, from a 9-mer phage peptide library, a phage clone displaying peptide capable of specific binding to S. aureus cell surface, namely St.au9IVS5 (sequence peptide RVRSAPSSS).The ability of the isolated phage clone to interact specifically with S. aureus and the efficacy of its bacteria-binding properties were established by using enzyme linked immune-sorbent assay (ELISA)...
June 17, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28654820/the-potential-value-of-preoperative-mri-texture-and-shape-analysis-in-grading-meningiomas-a-preliminary-investigation
#13
Peng-Fei Yan, Ling Yan, Ting-Ting Hu, Dong-Dong Xiao, Zhen Zhang, Hong-Yang Zhao, Jun Feng
OBJECT: Preoperative knowledge of meningioma grade is essential for planning treatment and surgery. The purpose of this study was to investigate the diagnostic value of MRI texture and shape analysis in grading meningiomas. METHODS: A surgical database was reviewed to identify meningioma patients who had undergone tumor resection between January 2015 and December 2016. Preoperative MR images were retrieved and analyzed. Texture and shape analysis was conducted to quantitatively evaluate tumor heterogeneity and morphology...
June 24, 2017: Translational Oncology
https://www.readbyqxmd.com/read/28654795/low-expression-of-long-noncoding-rna-casc2-indicates-a-poor-prognosis-and-promotes-tumorigenesis-in-thyroid-carcinoma
#14
Xiangqing Xiong, Hua Zhu, Xiangjian Chen
Recently, long noncoding RNAs (lncRNAs) have been shown to be linked to regulate different biological processes, such as cell growth, differentiation and tumorigenesis. LncRNAs have been identified to be promising clinical biomarkers in various tumors. Long noncoding RNAs cancer susceptibility candidate 2 (CASC2) has recently been demonstrated to be correlated to tumorigenesis in renal cell carcinoma, lung carcinoma, glioma, and gastric carcinoma. Nevertheless, the research on the biological function and clinical significance of CASC2 in thyroid carcinoma are still unclear...
June 24, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28654774/fkbp5-moderation-of-the-relationship-between-childhood-trauma-and-maladaptive-emotion-regulation-strategies-in-adolescents
#15
Thorhildur Halldorsdottir, Ana Paula Soares de Matos, Yvonne Awaloff, Eiríkur Örn Arnarson, W Edward Craighead, Elisabeth B Binder
Maladaptive emotion regulation strategies, such as rumination and catastrophizing, are transdiagnostic risk factors for psychopathology. FK506-binding protein 51 (FKBP5) has been found to moderate the relationship between stressful life events and various psychiatric disorders. Given the cross-disorder moderation effect of FKBP5 at the diagnostic level, the aim of the current study was to examine whether the relationship between exposure to childhood trauma and transdiagnostic maladaptive emotion regulation processes would also be moderated by genetic FKBP5 variation in a community sample of adolescents...
June 17, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28654766/methotrexate-related-lymphoproliferative-disorder-in-patients-with-osteonecrosis-of-the-jaw-a-3-case-report-and-literature-review
#16
Ken Furudate, Anna Satake, Norihiko Narita, Wataru Kobayashi
Patients with immunodeficiency or immunosuppression are at risk of developing a lymphoproliferative disorder (LPD). Methotrexate (MTX) is an iatrogenic cause of LPD, which in up to 50% cases occurs in extranodal sites. The occurrence of MTX-related LPD with osteonecrosis of the jaw (ONJ) has rarely been reported. Moreover, there are no clear diagnostic criteria and treatment strategies for management of these lesions. In the present cases, discontinuing MTX and debridement of the necrotic bone were effective...
June 1, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28654741/intestinal-parasites-in-stool-samples-and-perianal-swabs-examined-by-the-voivodeship-sanitary-epidemiological-station-in-bydgoszcz-between-2000-2014
#17
Jerzy Kasprzak, Bożena Szaładzińska, Małgorzata Smoguła, Marcin Ziuziakowski
INTRODUCTION: Epidemiological conditions are changing due to the modifications in human behavior and environment. Parasitic diseases are most often caused by intestinal parasites. The frequency of Echinococcus multilocularis and tropical diseases increases in Poland. AIM OF STUDY: Analysis of intestinal parasites’ occurrence in stool samples and perianal swabs tested in Medical Diagnostics Department of The Voivodeship Sanitary-Epidemiological Station in Bydgoszcz between 2000-2014...
2017: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/28654730/promises-pitfalls-and-practicalities-of-prenatal-whole-exome-sequencing
#18
Sunayna Best, Karen Wou, Neeta Vora, Ignatia B Van den Veyver, Ronald Wapner, Lyn S Chitty
Prenatal genetic diagnosis provides information for pregnancy and perinatal decision-making and management. In several small series, prenatal whole exome sequencing (WES) approaches have identified genetic diagnoses when conventional tests (karyotype and microarray) were not diagnostic. Here, we review published prenatal WES studies and recent conference abstracts. Twenty-nine studies were identified, with diagnostic rates varying between 6.2% and 80%. Differences in inclusion criteria and trio versus singleton approaches to sequencing largely account for the wide range of diagnostic rates...
June 27, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28654682/low-intensity-cognitive-behaviour-therapy-interventions-for-obsessive-compulsive-disorder-compared-to-waiting-list-for-therapist-led-cognitive-behaviour-therapy-3-arm-randomised-controlled-trial-of-clinical-effectiveness
#19
Karina Lovell, Peter Bower, Judith Gellatly, Sarah Byford, Penny Bee, Dean McMillan, Catherine Arundel, Simon Gilbody, Lina Gega, Gillian Hardy, Shirley Reynolds, Michael Barkham, Patricia Mottram, Nicola Lidbetter, Rebecca Pedley, Jo Molle, Emily Peckham, Jasmin Knopp-Hoffer, Owen Price, Janice Connell, Margaret Heslin, Christopher Foley, Faye Plummer, Christopher Roberts
BACKGROUND: Obsessive-compulsive disorder (OCD) is prevalent and without adequate treatment usually follows a chronic course. "High-intensity" cognitive-behaviour therapy (CBT) from a specialist therapist is current "best practice." However, access is difficult because of limited numbers of therapists and because of the disabling effects of OCD symptoms. There is a potential role for "low-intensity" interventions as part of a stepped care model. Low-intensity interventions (written or web-based materials with limited therapist support) can be provided remotely, which has the potential to increase access...
June 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28654650/risk-factors-for-prevalent-hepatitis-c-virus-infection-among-inmates-in-a-state-prison-system-in-mexico
#20
Pablo F Belaunzarán-Zamudio, Juan L Mosqueda-Gomez, Alejando Macias-Hernandez, Juan G Sierra-Madero, Saifuddin Ahmed, Chris Beyrer
OBJECTIVES: To estimate the prevalence of HCV-infection and identify associated factors among inmates in the State Prison System of Guanajuato in Mexico (Sep-2011 to Feb-2012). METHODS: Cross-sectional, observational study in 10 prisons in the State of Guanajuato in Mexico (2011-2012). We offered HCV-testing and applied audio computer-assisted self-interviews to all adults imprisoned in the State Prison System. We used a complex survey analysis to estimate the distribution of variables and its corresponding 95% confidence intervals, taking into consideration the expected cluster effect by common characteristics within prisons...
2017: PloS One
keyword
keyword
2452
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"