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Patient reported outcomes breast surgery

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https://www.readbyqxmd.com/read/29784600/breast-reconstruction-after-mastectomy-a-survey-of-surgeons-and-patients-perceptions
#1
Ariffuddin Ishak, Maya Mazuwin Yahya, Ahmad Sukari Halim
BACKGROUND: Breast reconstruction after mastectomy is important in breast cancer care. MATERIALS AND METHODS: A cross-sectional study was designed to assess surgeons' and patients' perceptions toward breast reconstruction. Questionnaires were distributed to general and breast surgeons in East Coast Malaysian hospitals and Hospital Kuala Lumpur and to postmastectomy patients with and without breast reconstruction at the Hospital Universiti Sains Malaysia and Hospital Raja Perempuan Zainab II...
April 28, 2018: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29770313/management-of-the-axilla-in-metaplastic-breast-carcinoma
#2
Brittany L Murphy, Robert T Fazzio, Tanya L Hoskin, Katrina N Glazebrook, Michael G Keeney, Elizabeth B Habermann, Tina J Hieken
Background: Metaplastic breast cancer (MBC), characterized by admixed epithelial, squamous or mesenchymal elements, constitutes <1% of breast cancers and has a poor prognosis but a paradoxically low reported rate of axillary lymph node (LN) involvement. Due to its rarity, data on appropriate axillary management is lacking, prompting this investigation of LN status and outcomes. Methods: We identified 41 MBC patients treated at our institution 2001-2011 who were followed for a median of 66 months...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29768500/clinically-relevant-inflammatory-breast-cancer-patient-derived-xenograft-derived-ex-vivo-model-for-evaluation-of-tumor-specific-therapies
#3
Bedrich L Eckhardt, Maria Gagliardi, LaKesla Iles, Kurt Evans, Cristina Ivan, Xiuping Liu, Chang-Gong Liu, Glauco Souza, Arvind Rao, Funda Meric-Bernstam, Naoto T Ueno, Geoffrey A Bartholomeusz
Inflammatory breast cancer (IBC) is a rare and aggressive presentation of invasive breast cancer with a 62% to 68% 5-year survival rate. It is the most lethal form of breast cancer, and early recognition and treatment is important for patient survival. Like non-inflammatory breast cancer, IBC comprises multiple subtypes, with the triple-negative subtype being overrepresented. Although the current multimodality treatment regime of anthracycline- and taxane-based neoadjuvant therapy, surgery, and radiotherapy has improved the outcome of patients with triple-negative IBC, overall survival continues to be worse than in patients with non-inflammatory locally advanced breast cancer...
2018: PloS One
https://www.readbyqxmd.com/read/29750758/quality-of-surgical-outcomes-reporting-in-plastic-surgery-a-15-year-analysis-of-complication-data
#4
Rajiv P Parikh, Ketan Sharma, Ali A Qureshi, Michael J Franco, Terence M Myckatyn
BACKGROUND: Postoperative complication data are integral to assessing patient outcomes and identifying areas to improve quality in surgical care. Accurate appraisal of surgical techniques requires consistency and reliability in complication data reporting. The purpose of this study was to analyze the quality of complication reporting in plastic surgery. METHODS: The authors critically reviewed the literature from January 1st, 2000 to December 31st, 2014 to identify articles reporting surgical outcomes after 3 index procedures (autologous breast reconstruction, prosthetic breast reconstruction and reduction mammaplasty)...
March 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29741462/complications-risk-factors-and-patients-reported-outcomes-after-skin-sparing-mastectomy-followed-by-breast-reconstruction-in-women-with-brca-mutations
#5
Ingvild O Moberg, Inger Schou Bredal, Michael R Schneider, Kim A Tønseth, Ellen Schlichting
BACKGROUND: Women with a BRCA mutation have the option of undergoing prophylactic mastectomy and immediate breast reconstruction; however, the potential negative effects of reconstruction on women's physical and psychological well-being are unclear. This study aimed to investigate complications, patient-reported pain, health-related quality-of-life (HRQoL) and satisfaction following reconstructive surgery at Oslo University Hospital between 2006 and 2013. METHODS: Data were collected retrospectively from the records of 238 patients...
May 9, 2018: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/29734255/patient-information-needs-and-breast-reconstruction-after-mastectomy-a-qualitative-meta-synthesis
#6
Tracey L Carr, Gary Groot, David Cochran, Lorraine Holtslander
BACKGROUND: Although many women benefit from breast reconstruction after mastectomy, several studies report women's dissatisfaction with the level of information they were provided with before reconstruction. OBJECTIVE: The present meta-synthesis examines the qualitative literature that explores women's experiences of breast reconstruction after mastectomy and highlights women's healthcare information needs. METHODS: After a comprehensive search of 6 electronic databases (CINAHL, Cochrane Library, EMBASE, MEDLINE, PsycINFO, and Scopus), we followed the methodology for synthesizing qualitative research...
April 27, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29734046/impact-of-neoadjuvant-chemotherapy-and-pathological-complete-response-on-eligibility-for-breast-conserving-surgery-in-patients-with-early-breast-cancer-a-meta-analysis
#7
Carmen Criscitiello, Mehra Golshan, William T Barry, Giulia Viale, Stephanie Wong, Michele Santangelo, Giuseppe Curigliano
PURPOSE: We conducted a meta-analysis of randomised trials evaluating pathological complete response (pCR) and surgical outcomes after neoadjuvant systemic therapy (NST) in patients with early breast cancer (EBC). PATIENTS AND METHODS: The primary outcome was breast-conserving surgery (BCT) rate. Secondary outcomes were pCR rate and association to BCT. Meta-analyses were performed using random effects models that use inverse-variance weighting for each treatment arm based on evaluable patients...
May 4, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29721214/distinct-molecular-subtypes-of-gastric-cancer-from-laur%C3%A3-n-to-molecular-pathology
#8
REVIEW
Magdalena Cisło, Agata Anna Filip, George Johan Arnold Offerhaus, Bogumiła Ciseł, Karol Rawicz-Pruszyński, Małgorzata Skierucha, Wojciech Piotr Polkowski
In Western countries the majority of gastric cancers (GC) are usually diagnosed in advanced stages reporting a 5-year survival rate of only 26%. The Laurén classification of GC was most widely used in clinical practice since it reflects GC morphology, epidemiology, tumor biology, clinical management and outcome. Despite the initial promise of individualizing antitumor treatment, the management of GC still remains relatively broad and general. Apart from clinical staging, molecular profiling enables targeting of the identified underlying alterations, rather than histology...
April 10, 2018: Oncotarget
https://www.readbyqxmd.com/read/29720750/newer-regional-analgesia-interventions-fascial-plane-blocks-for-breast-surgeries-review-of-literature
#9
REVIEW
Rakesh Garg, Swati Bhan, Saurabh Vig
Surgical resection of the primary tumour with axillary dissection is one of the main modalities of breast cancer treatment. Regional blocks have been considered as one of the modalities for effective perioperative pain control. With the advent of ultrasound, newer interventions such as fascial plane blocks have been reported for perioperative analgesia in breast surgeries. Our aim is to review the literature for fascial plane blocks for analgesia in breast surgeries. The research question for initiating the review was 'What are the reported newer regional anaesthesia techniques (fascial plane blocks) for female patients undergoing breast surgery and their analgesic efficacy?...
April 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29707442/the-functional-impact-of-breast-reconstruction-an-overview-and-update
#10
Jonas A Nelson, Iris T Lee, Joseph J Disa
As rates of bilateral mastectomy and immediate reconstruction rise, the aesthetic and psychosocial benefits of breast reconstruction are increasingly well understood. However, an understanding of functional outcome and its optimization is still lacking. This endpoint is critical to maximizing postoperative quality of life. All reconstructive modalities have possible functional consequences. Studies demonstrate that implant-based reconstruction impacts subjective movement, but patients' day-to-day function may not be objectively hindered despite self-reported disability...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29695917/four-cycles-of-adriamycin-and-cyclophosphamide-followed-by-four-cycles-of-docetaxel-nsabp-b27-with-concomitant-trastuzumab-as-neoadjuvant-therapy-for-high-risk-early-stage-her2-positive-breast-cancer-patients
#11
Hikmat Abdel-Razeq, Salwa S Saadeh, Mahmoud Abu-Nasser, Hazem Abdulelah, Lina Marie, Murad Salam, Basel Al-Haj Ali, Mohammad Ibrahim, Dalia Rimawi
Background: The majority of breast cancer patients in Jordan are diagnosed at a young age and present with metastatic or locally advanced disease. The National Surgical Adjuvant Breast and Bowel Project Protocol B27 (NSABP-B27) (four cycles of adriamycin and cyclophosphamide [AC] followed by four cycles of docetaxel) is a standard neoadjuvant regimen in our institution. In this study, we report the efficacy of adding trastuzumab to docetaxel in this regimen for high-risk human epidermal growth factor receptor 2 (HER2)-positive early-stage disease...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29695577/clinical-significance-of-the-neutrophil-to-lymphocyte-ratio-in-endocrine-therapy-for-stage-iv-breast-cancer
#12
Nozomi Iimori, Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Koji Takada, Katsuyuki Takahashi, Takaharu Hatano, Tsutomu Takashima, Shuhei Tomita, Hisashi Motomura, Kosei Hirakawa, Masaichi Ohira
BACKGROUND: Studies have found that patients with cancer exhibit abnormal leukocyte fractions, such as elevated neutrophil count and diminished lymphocyte count, and that the neutrophil-to-lymphocyte ratio (NLR) provides a surrogate marker for prognosis and response to treatment of patients after radical surgery for several different types of cancer. However, few reports have addressed the association between the NLR and response to endocrine therapy. In this study, we carried out a clinical investigation to confirm whether or not the NLR predicted the response to endocrine therapy of stage IV breast cancer...
May 2018: In Vivo
https://www.readbyqxmd.com/read/29693230/impact-of-port-site-scar-on-perception-of-patients-with-breast-cancer-patient-reported-outcomes
#13
Amy Voci, David Lee, Emily Ho, Rebecca Crane-Okada, Maggie DiNome
PURPOSE: As the number of survivors continues to increase with improvements in breast cancer treatment, greater emphasis has been placed on the aesthetic outcome following breast surgery. Effort is made to minimize scarring on the breast, yet patients who require a port for treatment inevitably have a scar on the upper chest from the port itself. We hypothesized that patients with breast cancer are conscious of their port scars, and if given a choice would prefer placement of the port in the arm rather than the chest...
April 24, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29685086/preoperative-localization-of-recurrence-in-the-thyroidectomy-bed-using-a-radioactive-iodine-125-seed
#14
Hillary W Garner, Ricardo Paz-Fumagalli, Geoffrey D Young
Intraoperative localization of nonpalpable recurrent thyroid cancer has been reported using needle localization, intraoperative ultrasound (US), dye injection, and radio-guided surgery. We describe the alternative technique of radioactive seed localization (RSL) in 3 patients with residual or recurrent papillary thyroid cancer. This technique has been used for many years in the setting of nonpalpable breast cancer, where it has been shown to be safe and has been associated with greater surgeon satisfaction as well as improved patient tolerability, cosmesis, and outcomes compared to needle localization...
April 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29678302/patient-reported-outcome-measures-in-breast-cancer-patients
#15
M Lagendijk, L S E van Egdom, C Richel, N van Leeuwen, C Verhoef, H F Lingsma, L B Koppert
INTRODUCTION: In the International Consortium for Health Outcome Measures (ICHOM) breast cancer outcome set Patient Reported Outcome Measurements (PROMs) form an important but rather innovative part. Few data exist on scores per type of breast surgery and how to use scores in surgical practice. We evaluated PROM scores as well as satisfaction with and expectations of the use of PROMs in breast cancer patients using the national and local patient advocate society. METHODS: Through an online survey patients were asked to report age, type of breast cancer surgery (whether Breast Conserving Therapy (BCT), mastectomy, autologous or implant breast reconstruction) and time since surgery...
March 21, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29671140/profiling-surgeon-performance-for-breast-cancer-lumpectomy-by-composite-measurement-of-reoperations-cosmetic-outcomes-and-patient-preferences
#16
Annie L Dunham, Luis D Ramirez, Choua A Vang, Jared H Linebarger, Jeffrey Landercasper
BACKGROUND: Patients want information to search for destination of care for breast-conserving surgery (BCS). To inform patients wanting a lumpectomy, we aimed to develop a pilot project that communicated composite quality measure (QM) results using a '4-star' rating system. Two patient-centered QMs were included in the model-reoperation rate (ROR) and cosmetic outcome (COSM). METHODS: A prospective database was reviewed for stage 0-3 patients undergoing initial lumpectomy by three surgeons from 2010 to 2015...
April 18, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29666911/dual-coverage-of-the-inferior-pole-with-conjoined-fascial-flap-and-acellular-dermal-matrix-for-immediate-one-stage-breast-reconstruction-with-a-prosthetic-implant
#17
Seo H Lee, Yong S Chun, Heung K Park, Yang W Kim, Young W Cheon
BACKGROUND: Elevation of a conjoined fascial flap composed of the pectoralis major, serratus anterior, and external oblique fascia is a type of surgical technique using autologous tissue to cover the lower pole after immediate one-stage direct-to-implant (DTI) breast reconstruction. However, volumetric breast implants hinder use of this technique alone. For better structural stability and more aesthetically favorable breast contour in large breasts, we have devised a technique involving dual coverage of the lower pole by a conjoined fascial flap and acellular dermal matrix (ADM)...
April 17, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29664825/outcomes-analysis-of-chief-cosmetic-clinic-over-13-years
#18
Nicholas J Walker, John C Crantford, Megan A Rudolph, Lisa R David
BACKGROUND: Adequate resident training in aesthetic surgery has become increasingly important with rising demand. Chief resident aesthetic clinics allow hands on experience with an appropriate amount of autonomy. The purpose of this study was to compare resident cosmetic clinic outcomes to those reported in the literature. Furthermore, we sought to assess how effective these clinics can be in preparing residents in performing common aesthetic surgery procedures. METHOD: A retrospective chart review of 326 patients and 714 aesthetic procedures in our chief cosmetic clinic over a 13-year period was performed, and complication and revision rates were recorded...
April 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29662532/cosmesis-after-early-stage-breast-cancer-treatment-with-surgery-and-radiation-therapy-experience-of-patients-treated-in-a-chilean-radiotherapy-centre
#19
Lorena Vargas, Sebastián Solé, Claudio Vicente Solé
Aim: To analyse the overall cosmetic outcome according to patient self-assessment in relation to the fractionation received. Materials and methods: A questionnaire, drawn up on the basis of subjective rating scales of cosmesis and of acute and late toxicity RTOG/EORTC, EORTC QLQ-C30 (v3) and LENT SOMA, was applied to patients with early-stage breast cancer who received radiotherapy with tangential fields between June 2014 and July 2015. Self-perception of cosmesis, changes in the treated breast, pain and fractionation used (hypofractionation (HF) 42...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29661153/improved-analgesia-and-reduced-post-operative-nausea-and-vomiting-after-implementation-of-an-enhanced-recovery-after-surgery-eras-pathway-for-total-mastectomy
#20
Catherine Chiu, Pedram Aleshi, Laura J Esserman, Christina Inglis-Arkell, Edward Yap, Elizabeth L Whitlock, Monica W Harbell
BACKGROUND: Enhanced Recovery After Surgery (ERAS) pathways have been shown in multiple surgical disciplines to improve outcomes, including reduced opioid consumption, length of stay, and post-operative nausea and vomiting (PONV). However, very few studies describe the application of ERAS to breast surgery and even fewer describe ERAS for outpatient surgery. We describe the implementation and efficacy of an Enhanced Recovery After Surgery (ERAS) pathway for total skin-sparing mastectomy with immediate reconstruction in an outpatient setting...
April 16, 2018: BMC Anesthesiology
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