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Patient reported outcomes breast surgery

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https://www.readbyqxmd.com/read/29145211/patient-reported-outcome-results-from-the-open-label-randomized-phase-iii-select-bc-trial-evaluating-first-line-s-1-therapy-for-metastatic-breast-cancer
#1
Takuya Kawahara, Kojiro Shimozuma, Takeru Shiroiwa, Yasuhiro Hagiwara, Yukari Uemura, Takanori Watanabe, Naruto Taira, Takashi Fukuda, Yasuo Ohashi, Hirofumi Mukai
OBJECTIVE: To evaluate the effects of S-1, an orally administered 5-FU agent, versus taxane on patient-reported outcomes (PROs) in the SELECT BC trial. METHODS: Patients with HER2-negative and endocrine treatment-resistant breast cancer with metastasis or recurrence after surgery were randomly assigned to receive first-line taxane or S-1. PROs (secondary endpoint) were assessed using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) and Patient Neurotoxicity Questionnaire (PNQ) at baseline and at 3, 6, and 12 months...
November 17, 2017: Oncology
https://www.readbyqxmd.com/read/29139613/nipple-sparing-mastectomy-as-treatment-for-patients-with-ductal-carcinoma-in%C3%A2-situ-a-10-year-follow-up-study
#2
Víctor Lago, Vincenzo Maisto, Julia Gimenez-Climent, Jose Vila, Carlos Vazquez, Rafael Estevan
The objective was to determine the 10-year oncological safety of nipple-sparing mastectomy (NSM) in patients diagnosed with ductal carcinoma in situ (DCIS). The use of NSM preserves the nipple-areola complex (NAC). As residual fibroglandular breast tissue can remain behind the spared NAC, its use for patient with breast cancer is controversial. The oncologic outcomes and complication rates after performing NSM compared to other techniques are still under debate and a concern when treating patients with breast cancer...
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29139592/single-dose-systemic-acetaminophen-to-improve-patient-reported-quality-of-recovery-after-ambulatory-segmental-mastectomy-a-prospective-randomized-double-blinded-placebo-controlled-clinical-trial
#3
Gildasio S De Oliveira, Meghan E Rodes, Jane Bialek, Mark C Kendall, Robert J McCarthy
Few systemic drug interventions are efficacious to improve patient reported quality of recovery after ambulatory surgery. We aimed to evaluate whether a single dose systemic acetaminophen improve quality of recovery in female patients undergoing ambulatory breast surgery. We hypothesized that patients receiving a single dose systemic acetaminophen at the end of the surgical procedure would have a better global quality of postsurgical recovery compared to the ones receiving saline. The study was a prospective randomized double blinded, placebo controlled, clinical trial...
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29132566/are-there-alternative-strategies-for-the-local-management-of-ductal-carcinoma-in-situ
#4
REVIEW
Kelly J Rosso, Anna Weiss, Alastair M Thompson
The management of ductal carcinoma in situ (DCIS) has traditionally followed the evidence base for invasive breast cancer using surgery, radiation therapy, and drug therapy to remove the DCIS from the breast and reduce the risk of recurrence for both DCIS and invasive breast cancer. Because of concerns regarding the overtreatment of DCIS, randomized controlled trials have been established to test the outcomes (invasive breast cancer outcomes and patient-reported outcome measures) of active surveillance compared with guideline-concordant care for low-risk (for progression) DCIS...
January 2018: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/29124379/use-of-the-breast-q%C3%A2-survey-in-the-prospective-evaluation-of-reduction-mammaplasty-outcomes
#5
Isaias Vieira Cabral, Edgard da Silva Garcia, Rebecca Neponucena Sobrinho, Natália Lana Larcher Pinto, Yara Juliano, Joel Veiga-Filho, Lydia Masako Ferreira, Daniela Francescato Veiga
INTRODUCTION: BREAST-Q™ is a patient-reported outcomes survey instrument with a specific module that evaluates breast reduction surgery. It allows assessment of patient's satisfaction with received treatment and evaluates the impact of surgery on different aspects of the patient's quality of life. This article aims to assess the satisfaction and quality of life of patients who underwent reduction mammaplasty. MATERIALS AND METHODS: Women aged between 18 and 60 years, with a body mass index ranging from 19 to 30 kg/m(2), who were already scheduled for reduction mammaplasty, were included in the study...
November 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29121898/clinicopathologic-and-prognostic-features-of-breast-cancer-in-young-women-a-series-from-north-of-morocco
#6
Joaira Bakkach, Mohamed Mansouri, Touria Derkaoui, Ali Loudiyi, Mohamed Fihri, Samia Hassani, Amina Barakat, Naima Ghailani Nourouti, Mohcine Bennani Mechita
BACKGROUND: Literature data reported a higher frequency of breast cancer in young women (BCYW) in developing countries. BCYW is associated with delayed diagnosis, aggressive biology and poor prognosis. However, our knowledge of biological profile, treatment received and outcome of young patients is still limited in Morocco. We propose to analyze clinicopathologic, therapeutic and prognostic features of BCYW among a series of patients native and/or inhabitant of North of Morocco. METHODS: We carried out a retro-prospective study of 331 infiltrating breast cancer cases registered between January 2010 and December 2015...
November 9, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29121845/improving-outcomes-for-lower-extremity-amputations-using-intraoperative-fluorescent-angiography-to-predict-flap-viability
#7
Andrew E Yang, Charles A Hartranft, Alisha Reiss, Charles R Holden
OBJECTIVES: Nearly 25% of vascular surgery patients operated on for peripheral vascular disease are readmitted within 30 days. Development of adjuncts to minimize wound complications remains an area of great interest. Here, we present our experience with intraoperative fluorescent angiography (IFA) as a tool to predict skin flap viability following lower extremity amputations (LEAs). METHODS: Experience with IFA using indocyanine green (ICG) dye was reviewed retrospectively at a single institution...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29116313/solitary-pancreatic-metastasis-from-breast-cancer-case-report-and-review-of-literature
#8
Márcio Apodaca-Rueda, Fábio Henrique Mendonça Chaim, Milena da Silva Garcia, Helena Paes de Almeida de Saito, Martinho Antonio Gestic, Murillo Pimentel Utrini, Francisco Callejas-Neto, Elinton Adami Chaim, Everton Cazzo
ABSTRACT: HASH(0x2f6fd90) CONTEXT: Pancreatic metastases from primary malignant tumors at other sites are rare, constituting about 2% of the neoplasms that affect the pancreas. Pancreatic metastasis from breast cancer is extremely rare and difficult to diagnose, because its clinical and radiological presentation is similar to that of a primary pancreatic tumor. CASE REPORT: A 64-year-old female developed a lesion in the pancreatic tail 24 months after neoadjuvant therapy, surgery and adjuvant radiation therapy for right-side breast cancer (ductal carcinoma)...
November 6, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29102440/patient-satisfaction-with-radioguided-occult-lesion-localisation-using-iodine-125-seeds-rollis-versus-conventional-hookwire-localisation
#9
Jeremy S L Ong, Joelin Teh, Christobel Saunders, Anita G Bourke, Catalina Lizama, Jade Newton, Michael Phillips, Donna B Taylor
BACKGROUND: Women with impalpable or poorly palpable breast cancer require radiologically guided localisation prior to breast conserving surgery. Radioguided Occult Lesion Localisation using Iodine-125 Seed (ROLLIS) is an emerging alternative to conventional Hookwire Localisation (HWL). We compared ROLLIS with conventional HWL with respect to patient reported stress and discomfort related to the localisation procedure. PATIENTS AND METHODS: From September 2013 to January 2016, women who were eligible for breast conserving surgery with impalpable or poorly palpable histologically confirmed invasive or in-situ carcinoma were recruited to the multi-centre ROLLIS randomised controlled trial and underwent either ROLLIS or HWL...
October 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29095832/multi-center-study-on-patient-selection-for-and-the-oncologic-safety-of-intraoperative-radiotherapy-iort-with-the-xoft-axxent%C3%A2-ebx%C3%A2-system-for-the-management-of-early-stage-breast-cancer-in-taiwan
#10
Hung-Wen Lai, Liang-Chih Liu, Fu Ouyang, Chung-Chin Yao, Hsiang-Chun Jan, Ya-Herng Chang, Chi-Wen Tu, Dar-Ren Chen, Tsui-Fen Cheng, Yen-Dun Tzeng, Huan-Ming Hsu, Ming-Hsin Yeh, Yao-Chung Wu, Po-Sheng Yang, Hung-Bun Lam, Ming-Feng Hou, Fang-Ming Chen
BACKGROUND: In this multi-center study, we report the patient selection criteria for and preliminary oncologic outcomes associated with intraoperative radiotherapy (IORT) delivered by the Xoft Axxent® eBx® system for early-stage breast cancer in Taiwan. METHODS: Patients with early breast cancer in Taiwan received breast conserving surgery and received IORT with Xoft Axxent® eBx® System during 2013-2015 was search from database of Taiwan IORT study cooperative group (T-IORTSCG)...
2017: PloS One
https://www.readbyqxmd.com/read/29081405/the-enigma-of-granulomatous-mastitis-a-series
#11
Muhammad Umair Bashir, Alexius Ramcharan, Sarah Alothman, Sabine Beaugris Pa-C, Sarosh Ahmad Khan, Mohammed A Sbeih, Ryan Engdahl
Granulomatous mastitis is a chronic inflammatory breast disease with an enigmatic clinical presentation that can delay diagnosis and perpetuate ineffective treatments. We report our experience with the diagnosis and management of eighteen cases of granulomatous mastitis in the setting of an urban public hospital. The patients were identified after a retrospective review of pathology and surgery databases. Demographic, clinical, radiographic, histopathological data and treatment responses were reviewed. Out of a total of 18 patients, 8 patients were noted to be from Mexico...
February 20, 2017: Breast Disease
https://www.readbyqxmd.com/read/29069879/the-surgical-impact-of-e-cigarettes-a-case-report-and-review-of-the-current-literature
#12
Megan Fracol, Robert Dorfman, Lindsay Janes, Swati Kulkarni, Kevin Bethke, Nora Hansen, John Kim
We report a case of a 51 year old female with a 25 pack year smoking history who underwent bilateral mastectomy and immediate tissue expander reconstruction for newly diagnosed right breast cancer. The patient reported herself as a non-smoker despite significant e-cigarette use, with resulting significant mastectomy skin flap necrosis and breast reconstruction failure. Little is known about the physiologic effect of e-cigarettes on wound healing and tissue perfusion. To this end, we provide an updated review of the impact of e-cigarettes on surgical outcomes...
October 26, 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29068922/breast-cleavage-remodeling-with-fat-grafting-a-safe-way-to-optimize-symmetry-and-to-reduce-intermammary-distance
#13
José Maria Serra-Mestre, Randolfo Fernandez Peñuela, Vanessa Foti, Francesco D'Andrea, José Maria Serra-Renom
BACKGROUND: In their descriptions of the ideal breast, most studies have focused primarily on the dimensions, shape, and proportions. The distance between the breasts has only very rarely been considered. The intermammary distance and the medial symmetry between the breasts are important parts of the outcome of surgery and have a strong bearing on patient satisfaction. However, the control surgeons have over these factors is only relative, and depends heavily on the underlying anatomical characteristics of the patients...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29064917/current-trends-in-postmastectomy-breast-reconstruction
#14
REVIEW
Hina Panchal, Evan Matros
Postmastectomy immediate breast reconstruction in the U.S. continues to experience an upward trend owing to heightened awareness, innovations in reconstructive technique, growing evidence of improved patient-reported outcomes, and shifts in mastectomy patterns. Women with unilateral breast cancer are increasingly electing to undergo contralateral prophylactic mastectomy, instead of unilateral mastectomy or opting for breast conservation. The ascent in prophylactic surgeries correlates temporally to a shift toward prosthetic methods of reconstruction as the most common technique...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29043480/body-mass-index-bmi-postoperative-appearance-satisfaction-and-sexual-function-in-breast-cancer-survivorship
#15
K E Rojas, N Matthews, C Raker, M A Clark, M Onstad, A Stuckey, J Gass
PURPOSE: We sought to explore the correlation between BMI and postoperative sexual function, body image, and breast-specific sensuality before and after breast cancer surgery. METHODS: A cross-sectional survey of patients at least 1 year from surgery employed the Female Sexual Function Index (FSFI) and investigator-generated questions. Patients who underwent lumpectomy (L), mastectomy (M), and mastectomy with reconstruction (MR) were compared across three BMI groups: normal weight, overweight, and obese...
October 17, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28984537/neurosurgical-transection-of-the-breast-an-unexpected-extracranial-complication-of-ventriculoperitoneal-shunt-insertion
#16
Molly Jakeman, Ranjeet Jeevan, Sasha C Burn, Sian Falder
Ventriculoperitoneal (VP) shunt placement is among the most common surgical procedures undertaken by neurosurgeons. Complications arising from the thoracic portion of the shunt are relatively rare in comparison with those of the intraventricular and peritoneal portions. Disruption of primary breast development following VP shunt placement has not previously been reported. The authors describe the case of a 15-year-old girl referred to the plastic surgery department with a significant right breast deformity and associated asymmetry following VP shunt placement performed during the neonatal period...
October 6, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28982914/surgical-resection-and-outcome-of-synchronous-and-metachronous-primary-lung-cancer-in-breast-cancer-patients
#17
Fumihiro Shoji, Nami Yamashita, Yuka Inoue, Yuka Kozuma, Gouji Toyokawa, Fumihiko Hirai, Kensaku Ito, Tetsuzo Tagawa, Tatsuro Okamoto, Yoshihiko Maehara
BACKGROUND/AIM: Women with breast cancer are at increased risk of subsequent primary malignancies, specifically lung cancer. The aim of this study was to report the frequency of lung cancer in patients with breast cancer, and patients' characteristics and surgical outcomes. PATIENTS AND METHODS: We investigated 1,066 consecutive female patients undergoing surgical resection for breast cancer and 666 undergoing surgical resection for lung cancer. RESULTS: Lung cancer with breast cancer was observed in 14 patients (1...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28982848/lipofilling-outcomes-mimicking-breast-cancer-recurrence-case-report-and-update-of-the-literature
#18
REVIEW
Silvia Gigli, Maria Ida Amabile, Francesca DI Pastena, Alessandro DE Luca, Caterina Gulia, Lucia Manganaro, Massimo Monti, Laura Ballesio
Breast lipofilling uses autologous fat grafting to correct breast defects after radical or conservative surgery. After early concerns regarding its application in reconstruction after breast cancer (BC), in 2009 the American Society of Plastic Surgeons formed a task force to assess the indications, safety and efficacy of autologous fat grafting. We report the case of a woman who came to our attention for a painful swelling of the left breast. She had undergone breast-conserving therapy for BC, followed by lipofilling...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28971987/healthcare-system-distrust-physician-trust-and-patient-discordance-with-adjuvant-breast-cancer-treatment-recommendations
#19
Lorraine T Dean, Shadiya L Moss, Anne Marie McCarthy, Katrina Armstrong
BACKGROUND: Adjuvant therapy after breast cancer surgery decreases recurrence and increases survival, yet not all women receive and complete it. Previous research has suggested that distrust in medical institutions plays a role in who initiates adjuvant treatment, but has not assessed treatment completion treatment, nor the potential mediating role of physician distrust. METHODS: Women listed in Pennsylvania and Florida cancer registries, who were under the age of 65 when diagnosed with localized invasive breast cancer between 2005 and 2007, were surveyed by mail in 2007-2009...
September 29, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28969622/a-study-protocol-of-the-effectiveness-of-pegasus-a-multi-centred-study-comparing-an-intervention-to-promote-shared-decision-making-about-breast-reconstruction-with-treatment-as-usual
#20
Diana Harcourt, Nicole Paraskeva, Paul White, Jane Powell, Alex Clarke
BACKGROUND: Increasingly, women elect breast reconstruction after mastectomy. However, their expectations of surgery are often not met, and dissatisfaction with outcome and ongoing psychosocial concerns and distress are common. We developed a patient-centered intervention, PEGASUS:(Patients' Expectations and Goals: Assisting Shared Understanding of Surgery) which supports shared decision making by helping women clarify their own, individual goals about reconstruction so that they can discuss these with their surgeon...
October 2, 2017: BMC Medical Informatics and Decision Making
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