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Patient reported outcomes breast surgery

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https://www.readbyqxmd.com/read/28077134/endoscopy-assisted-surgery-for-the-management-of-benign-breast-tumors-technique-learning-curve-and-patient-reported-outcome-from-preliminary-323-procedures
#1
Hung-Wen Lai, Hui-Yu Lin, Shu-Ling Chen, Shou-Tung Chen, Dar-Ren Chen, Shou-Jen Kuo
BACKGROUND: Endoscopy-assisted breast surgery (EABS), a technique that optimizes cosmetic outcome because it is performed through small wounds hidden in inconspicuous areas, could be an alternative surgical technique for benign breast tumors. In this study, we report the preliminary results of 323 EABS procedures performed at our institution for the management of benign breast tumors. METHODS: The medical records of patients who underwent EABS for benign breast lesions during the periods August 2010 to December 2015 were collected from the Changhua Christian Hospital EABS database...
January 11, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28066801/cell-assisted-lipotransfer-in-breast-augmentation-and-reconstruction-a-systematic-review-of-safety-efficacy-use%C3%A2-of%C3%A2-patient-reported-outcomes-and-study-quality
#2
Zeeshaan Arshad, Lindsey Karmen, Rajan Choudhary, James A Smith, Olivier A Branford, David A Brindley, David Pettitt, Benjamin M Davies
BACKGROUND: Cell assisted lipotransfer serves as a novel technique for both breast reconstruction and breast augmentation. This systematic review assesses the efficacy, safety and use of patient reported outcome measures in studies involving cell assisted lipotransfer. We also carry out an objective assessment of study quality focussing on recruitment, follow-up and provide an up-to-date clinical trial landscaping analysis. METHODS: Key electronic databases were searched according to PRISMA guidelines and pre-defined inclusion and exclusion criteria...
December 2016: JPRAS Open
https://www.readbyqxmd.com/read/28044202/cosmetic-changes-following-surgery-and-accelerated-partial-breast-irradiation-using-hdr-interstitial-brachytherapy-evaluation-by-a%C3%A2-multidisciplinary-multigender-committee
#3
Tamer Soror, György Kovács, Nina Seibold, Corinna Melchert, Kristin Baumann, Eike Wenzel, Suzana Stojanovic-Rundic
BACKGROUND: Patients with early-stage breast cancer can benefit from adjuvant accelerated partial breast irradiation (APBI) following breast-conserving surgery (BCS). This work reports on cosmetic results following APBI using multicatheter high-dose-rate interstitial brachytherapy (HDR-IBT). PATIENTS AND METHODS: Between 2006 and 2014, 114 patients received adjuvant APBI using multicatheter HDR-IBT. For each patient, two photographs were analyzed: the first was taken after surgery (baseline image) and the second at the last follow-up visit...
January 2, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28040314/aesthetic-and-functional-outcome-after-breast-conserving-surgery-comparison-between-conventional-and-oncoplastic-resection
#4
K Ojala, T J Meretoja, M H K Leidenius
BACKGROUND: Recent studies implicate that oncoplastic breast cancer surgery provides better aesthetic outcome than conventional resection. Several factors have been associated with poor aesthetic outcome. This study aims to compare patient-reported aesthetic and functional outcome after conventional and oncoplastic resection and to evaluate prognostic factors for poor aesthetic outcome in a population-based setting. METHODS: 637 patients having breast conserving treatment (BCT) due to unilateral primary breast cancer at a single hospital district during 2010 were included...
December 18, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28036267/microrna-603-acts-as-a-tumor-suppressor-and-inhibits-triple-negative-breast-cancer-tumorigenesis-by-targeting-elongation-factor-2-kinase
#5
Recep Bayraktar, Martin Pichler, Pinar Kanlikilicer, Cristina Ivan, Emine Bayraktar, Nermin Kahraman, Burcu Aslan, Serpil Oguztuzun, Mustafa Ulasli, Ahmet Arslan, George Calin, Gabriel Lopez-Berestein, Bulent Ozpolat
Triple negative breast cancer (TNBC) is an aggressive type of breast cancer characterized by the absence of defined molecular targets, including estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and is associated with high rates of relapse and distant metastasis despite surgery and adjuvant chemotherapy. The lack of effective targeted therapies for TNBC represents an unmet therapeutic challenge. Eukaryotic elongation factor 2 kinase (eEF2K) is an atypical calcium/calmodulin-dependent serine/threonine kinase that promotes TNBC tumorigenesis, progression, and drug resistance, representing a potential novel molecular target...
December 27, 2016: Oncotarget
https://www.readbyqxmd.com/read/28032163/transition-from-round-to-shaped-implants-in-immediate-breast-reconstruction-our-preferred-approach-and-clinical-outcomes
#6
Thomas A Imahiyerobo, Kevin H Small, Robyn Sackeyfio, Hannah Hoffman, Mia Talmor
BACKGROUND: Smooth, round, silicone implants predominate device-based breast reconstruction in the USA; despite their prevalence, complications can include bottoming out, superior contour deformity, rippling, and/or lateral malposition. This complication profile increases the need for revision surgery and subsequent patient dissatisfaction. With the resurgence of shaped, textured, silicone implants in the USA, we report the senior author's success with these devices and outline a strategy to optimize outcomes in breast reconstruction surgery...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28032155/serratus-anterior-fascia-flap-versus-muscular-flap-for-expander-coverage-in-two-stage-breast-reconstruction-following-mastectomy-early-post-operative-outcomes
#7
Daniele Bordoni, Pierfrancesco Cadenelli, Nicola Rocco, Ariel Tessone, Giuseppe Falco, Cesare Magalotti
INTRODUCTION: The demand for reconstructive breast surgery after mastectomy is increasing among women and the two-stage option remains the most commonly performed technique. We conducted a self-controlled prospective clinical trial comparing the use of the serratus anterior fascia with the serratus anterior detached fibers to cover the inferolateral aspect of the expander in immediate two-stage breast reconstruction following conservative mastectomies as oncological or risk-reducing procedures...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28027256/evidence-based-medicine-autologous-breast-reconstruction
#8
Sheina A Macadam, Esta S Bovill, Edward W Buchel, Peter A Lennox
LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Gain an understanding of the different methods of autologous reconstruction available. 2. Understand the timing of autologous breast reconstruction and the impact of adjuvant and neoadjuvant treatments. 3 Understand the factors necessary for a comprehensive patient assessment. 4. Gain knowledge of patient factors that will affect autologous reconstruction and potential contraindications. 5. Summarize the patient-reported and clinical outcomes of autologous breast reconstruction...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28008267/oncological-outcomes-and-complications-after-volume-replacement-oncoplastic-breast-conservations-the-glasgow-experience
#9
Weiguang Ho, Sheila Stallard, Julie Doughty, Elizabeth Mallon, Laszlo Romics
INTRODUCTION: Oncoplastic breast conservation surgery (OBCS) combines the principles of surgical oncology and plastic surgery. OBCS has now become a growing option for the treatment of breast cancer and forms a part of breast-conserving therapy (BCT). We sought to investigate and report our experience in two breast units in Glasgow (Victoria Infirmary and Western Infirmary) on volume replacement OBCS. MATERIALS AND METHODS: Details of patients treated with volume replacement OBCS were identified from a prospectively recorded database from November 2010 to October 2015...
2016: Breast Cancer: Basic and Clinical Research
https://www.readbyqxmd.com/read/28007583/towards-a-privacy-preserving-cohort-discovery-framework-for-clinical-research-networks
#10
Jiawei Yuan, Bradley Malin, François Modave, Yi Guo, William R Hogan, Elizabeth Shenkman, Jiang Bian
BACKGROUND: The last few years have witnessed an increasing number of clinical research networks (CRNs) focused on building large collections of data from electronic health records (EHRs), claims, and patient-reported outcomes (PROs). Many of these CRNs provide a service for the discovery of research cohorts with various health conditions, which is especially useful for rare diseases. Supporting patient privacy can enhance the scalability and efficiency of such processes; however, current practice mainly relies on policy, such as guidelines defined in the Health Insurance Portability and Accountability Act (HIPAA), which are insufficient for CRNs (e...
December 19, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28006719/male-breast-cancer-modified-radical-mastectomy-or-breast-conservation-surgery-a-case-report-and-review-of-the-literature
#11
Gabriele Giunta, Matteo Rossi, Francesca Toia, Gaetana Rinaldi, Adriana Cordova
INTRODUCTION: Male breast cancer (MBC) is a rare disease that accounts for <1% of breast cancer cases. The most common treatment is modified radical mastectomy (MRM). Recently, breast conservative surgery (BCS) is getting popular for MBC treatment. We report a case and reviewed the literature to investigate whether emerging BCS can be considered as an alternative of a more radical surgery. PRESENTATION OF CASE: A 46 y.o. patient, presented with a painless left breast lump over a period of six months...
November 19, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28004220/recurrence-risk-perception-and-quality-of-life-following-treatment-of-breast-cancer
#12
Sarah T Hawley, Nancy K Janz, Kent A Griffith, Reshma Jagsi, Christopher R Friese, Allison W Kurian, Ann S Hamilton, Kevin C Ward, Monica Morrow, Lauren P Wallner, Steven J Katz
PURPOSE: Little is known about different ways of assessing risk of distant recurrence following cancer treatment (e.g., numeric or descriptive). We sought to evaluate the association between overestimation of risk of distant recurrence of breast cancer and key patient-reported outcomes, including quality of life and worry. METHODS: We surveyed a weighted random sample of newly diagnosed patients with early-stage breast cancer identified through SEER registries of Los Angeles County & Georgia (2013-14) ~2 months after surgery (N = 2578, RR = 71%)...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28003321/collaborative-care-intervention-for-the-perceived-care-needs-of-women-with-breast-cancer-undergoing-adjuvant-therapy-after-surgery-a-feasibility-study
#13
Kanae Momino, Miyashita Mitsunori, Hiroko Yamashita, Tatsuya Toyama, Hiroshi Sugiura, Nobuyasu Yoshimoto, Kei Hirai, Tatsuo Akechi
OBJECTIVE: This study aimed to investigate the feasibility of an intervention program for women with breast cancer undergoing adjuvant anticancer therapy, and determine its preliminary effectiveness in reducing their unmet needs and psychological distress. METHODS: The intervention was based on the collaborative care model, and compromised four domains: identification of unmet needs, problem-solving therapy and behavioral activation supervised by a psychiatrist, psychoeducation and referral to relevant departments...
December 20, 2016: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27996199/chronic-postsurgical-pain-outcomes-in-breast-reconstruction-patients-receiving-perioperative-transversus-abdominis-plane-catheters-at-the-donor-site-a-prospective-cohort-follow-up-study
#14
Justin Oh, Gabrielle M Pagé, Toni Zhong, Stuart McCluskey, Coimbatore Srinivas, Anne C O'Neill, James Kahn, Joel Katz, Stefan O P Hofer, Hance Clarke
BACKGROUND: Chronic postsurgical pain (CPSP) is a debilitating and costly condition. Risk factors for CPSP after autologous breast reconstruction have not been clearly established. Previously, we demonstrated that transversus abdominis plane (TAP) catheters delivering intermittent local anesthetic reduced postoperative morphine consumption. This prospective follow-up study aims to (1) compare the incidence of CPSP after autologous breast reconstruction between patients who received postoperative intermittent TAP catheters with bupivacaine or saline boluses and (2) assess the factors that contribute to the development and maintenance of CPSP in this study cohort...
December 20, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27993816/final-efficacy-and-updated-safety-results-of-the-randomized-phase-iii-beatrice-trial-evaluating-adjuvant-bevacizumab-containing-therapy-in-triple-negative-early-breast-cancer
#15
R Bell, J Brown, M Parmar, M Toi, T Suter, G G Steger, X Pivot, J Mackey, C Jackisch, R Dent, P Hall, N Xu, L Morales, L Provencher, R Hegg, L Vanlemmens, A Kirsch, A Schneeweiss, N Masuda, F Overkamp, D Cameron
PURPOSE: To assess the long-term impact of adding bevacizumab to adjuvant chemotherapy for early triple-negative breast cancer (TNBC). METHODS: Patients eligible for the open-label randomized phase III BEATRICE trial had centrally confirmed triple-negative operable primary invasive breast cancer (pT1a-pT3). Investigators selected anthracycline- and/or taxane-based chemotherapy for each patient. After definitive surgery, patients were randomized 1:1 to receive ≥4 cycles of chemotherapy alone or with 1 year of bevacizumab (5 mg/kg/week equivalent)...
December 19, 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/27991695/application-of-extended-bi-pedicle-anterolateral-thigh-free-flaps-for-reconstruction-of-large-defects-a-case-series
#16
Michele Maruccia, Georgios Orfaniotis, Pedro Ciudad, Fabio Nicoli, Emanuele Cigna, Giuseppe Giudice, Kidakorn Kiranantawat, Diego Ribuffo, Hung-Chi Chen
BACKGROUND: The anterolateral thigh flap is a workforce flap in reconstructive surgery, however, variations in it is vascular anatomy are not uncommon. These variations may affect flap design and survival, especially when large flaps are required. In some anatomical variants the anterolateral thigh flap is supplied by two separate dominant pedicles, and in these cases a bi-pedicle modification may be necessary to ensure complete flap viability. The aim of this report is to evaluate the outcomes, and present our approach in using bi-pedicle anterolateral thigh flaps as a method to reduce the risk of partial flap necrosis when reconstructing sizeable soft tissue defects...
December 19, 2016: Microsurgery
https://www.readbyqxmd.com/read/27987454/patient-reported-outcomes-in-ductal-carcinoma-in-situ-a-systematic-review
#17
REVIEW
Madeleine T King, Zoë E Winters, Ivo A Olivotto, Andrew J Spillane, Boon H Chua, Christobel Saunders, A Helen Westenberg, G Bruce Mann, Petrina Burnett, Phyllis Butow, Claudia Rutherford
Ductal carcinoma in situ (DCIS) is a pre-invasive breast cancer with excellent prognosis but with potential adverse impacts of diagnosis and treatment on quality of life and other patient-reported outcomes (PROs). We undertook a systematic review to synthesise current evidence about PROs following diagnosis and treatment for DCIS. We searched five electronic databases (from database inception to November 2015), cross-referenced and contacted experts to identify studies that reported PROs after DCIS treatment...
January 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/27965859/the-ibra-implant-breast-reconstruction-evaluation-study-protocol-for-a-prospective-multi-centre-cohort-study-to-inform-the-feasibility-design-and-conduct-of-a-pragmatic-randomised-clinical-trial-comparing-new-techniques-of-implant-based-breast-reconstruction
#18
Shelley Potter, Elizabeth J Conroy, Paula R Williamson, Steven Thrush, Lisa J Whisker, Joanna M Skillman, Nicola L P Barnes, Ramsey I Cutress, Elizabeth M Teasdale, Nicola Mills, Senthurun Mylvaganam, Olivier A Branford, Katherina McEvoy, Abhilash Jain, Matthew D Gardiner, Jane M Blazeby, Christopher Holcombe
BACKGROUND: Implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive procedure in the UK. The introduction of techniques to augment the subpectoral pocket has revolutionised the procedure, but there is a lack of high-quality outcome data to describe the safety or effectiveness of these techniques. Randomised controlled trials (RCTs) are the best way of comparing treatments, but surgical RCTs are challenging. The iBRA (implant breast reconstruction evaluation) study aims to determine the feasibility, design and conduct of a pragmatic RCT to examine the effectiveness of approaches to IBBR...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27943007/the-impact-of-doctor-patient-communication-on-patients-perceptions-of-their-risk-of-breast-cancer-recurrence
#19
Nancy K Janz, Yun Li, Brian J Zikmund-Fisher, Reshma Jagsi, Allison W Kurian, Lawrence C An, M Chandler McLeod, Kamaria L Lee, Steven J Katz, Sarah T Hawley
PURPOSE: Doctor-patient communication is the primary way for women diagnosed with breast cancer to learn about their risk of distant recurrence. Yet little is known about how doctors approach these discussions. METHODS: A weighted random sample of newly diagnosed early-stage breast cancer patients identified through SEER registries of Los Angeles and Georgia (2013-2015) was sent surveys about ~2 months after surgery (Phase 2, N = 3930, RR 68%). We assessed patient perceptions of doctor communication of risk of recurrence (i...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27940906/unraveling-factors-influencing-early-seroma-formation-in-breast-augmentation-surgery
#20
Marcos Sforza, Rodwan Husein, Connor Atkinson, Renato Zaccheddu
BACKGROUND: It is often assumed that seroma formation trails closely behind with incidence rates reported at 1 to 2%. Seroma is highly problematic for both the surgeon and patient and results in both patient anxiety and discomfort, succeeded by frequent outpatient visits, follow-up treatment, increased costs, and potentially hampered aesthetic outcomes. Consequently, it is now more important than ever to study seroma and to assess its pathophysiology and mechanisms of prevention. OBJECTIVES: The aim of this study was to isolate and identify risk factors that may be associated with early seroma formation...
December 9, 2016: Aesthetic Surgery Journal
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