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Fetal biometry

Emilio A Herrera, Francisca Cifuentes-Zúñiga, Esteban Figueroa, Cristian Villanueva, Cherie Hernández, René Alegría, Viviana Arroyo, Estefania Peñaloza, Marcelo Farías, Ricardo Uauy, Paola Casanello, Bernardo J Krause
In humans, intrauterine growth restriction (IUGR) is associated with vascular dysfunction, oxidative stress and signs of endothelial programming in umbilical vessels. We aimed to determine the effects of maternal antioxidant treatment with N-acetyl cysteine (NAC) on fetal endothelial function and eNOS programming in IUGR guinea pigs. IUGR was induced by implanting ameroid constrictors on uterine arteries of pregnant guinea pigs at mid gestation, receiving half of the sows NAC in the drinking water (from day 34 until term)...
October 14, 2016: Journal of Physiology
Gavin P Guy, Hua Z Ling, Mirian Machuca, Liona C Poon, Kypros H Nicolaides
OBJECTIVE: To evaluate the relationship between maternal cardiovascular parameters and neonatal birthweight and examine the potential value of these parameters in improving the prediction of small for gestational age (SGA) and large for gestational age (LGA) neonates provided by maternal characteristics and medical history. METHODS: In 2,835 singleton pregnancies maternal characteristics and medical history were recorded and maternal cardiovascular parameters were measured...
October 5, 2016: Ultrasound in Obstetrics & Gynecology
Owen J Arthurs, A Rega, F Guimiot, N Belarbi, J Rosenblatt, V Biran, M Elmaleh, G Sebag, M Alison
OBJECTIVES: Diffusion weighted magnetic resonance imaging (DWI) is a sensitive method to assess brain maturation or detect brain lesions, providing Apparent Diffusion Coefficient (ADC) values as a measure of water diffusion. Abnormal ADC values are seen in ischemic brain lesions, such as acute or chronic hypoxia. The aim of this study was to assess whether ADC values in the fetal brain were different in a group of fetuses exposed to severe vascular intrauterine growth restriction, compared to normal controls...
October 5, 2016: Ultrasound in Obstetrics & Gynecology
William Johnson, Momodou K Darboe, Fatou Sosseh, Patrick Nshe, Andrew M Prentice, Sophie E Moore
Prenatal supplementation with protein-energy (PE) and/or multiple-micronutrients (MMNs) may improve fetal growth, but trials of lipid-based nutritional supplements (LNSs) have reported inconsistent results. We conducted a post-hoc analysis of non-primary outcomes in a trial in Gambia, with the aim to test the associations of LNS with fetal growth and explore how efficacy varies depending on nutritional status. The sample comprised 620 pregnant women in an individually randomized, partially blinded trial with four arms: (a) iron and folic acid (FeFol) tablet (usual care, referent group), (b) MMN tablet, (c) PE LNS, and (d) PE + MMN LNS...
October 2, 2016: Maternal & Child Nutrition
G Ambroise Grandjean, M Chamagne, G Hossu, E Perdriolle-Galet, O Morel
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
J Zhang
No abstract text is available yet for this article.
September 2016: BJOG: An International Journal of Obstetrics and Gynaecology
Yky Cheng, T Y Leung, Tth Lao, Y M Chan, D S Sahota
OBJECTIVE: To assess the impact of adopting the INTERGROWTH-21(st) biometry standards in a Chinese population. DESIGN: Retrospective cohort study. SETTING: A teaching hospital in Hong Kong. POPULATION: A total of 10 527 Chinese women with a singleton pregnancy having a second- or third-trimester fetal anomaly or growth scan between January 2009 and June 2014. METHODS: Z-scores were derived for fetal abdominal circumference (AC), head circumference (HC), and femur length (FL) using the INTERGROWTH-21(st) and Chinese biometry standards...
September 2016: BJOG: An International Journal of Obstetrics and Gynaecology
Ranjit Akolekar, Mayumi Tokunaka, Nelson Ortega, Argyro Syngelaki, Kypros H Nicolaides
OBJECTIVES: To evaluate the performance of screening for all stillbirths and those due to impaired placentation and unexplained or other causes by a combination of maternal factors, fetal biometry and uterine artery pulsatility index (UT-PI) at 19-24 weeks' gestation and compare this performance to that of screening by UT-PI alone. METHODS: This was a prospective screening study of 70,003 singleton pregnancies including 69,735 live births and 268 (0.38%) antepartum stillbirths; 159 (59%) were secondary to impaired placentation and 109 (41%) were due to other or unexplained causes...
September 7, 2016: Ultrasound in Obstetrics & Gynecology
Alessandra Familiari, Carolina Scala, Maddalena Morlando, Amar Bhide, Asma Khalil, Basky Thilaganathan
INTRODUCTION: To evaluate the relative value of mid trimester fetal growth, uterine artery (UtA) Doppler indices and maternal demographics in prediction of stillbirth. MATERIAL AND METHODS: Retrospective cohort study; 23,894 singleton pregnancies routinely scanned between 19 and 24 weeks' gestation. Maternal characteristics included age, body mass index, ethnicity and medical history. Fetal biometry indices, birthweight and UtA pulsatility index (PI) values were converted to percentiles and multivariable logistic regression analysis was performed...
September 2, 2016: Acta Obstetricia et Gynecologica Scandinavica
Jean Edgard Aupont, Ranjit Akolekar, Aurora Illian, Stratos Neonakis, Kypros H Nicolaides
OBJECTIVES: To investigate whether measurement of maternal serum placental growth factor (PLGF) at 19-24 weeks' gestation improves the performance of screening for stillbirths that is achieved by a combination of maternal factors, fetal biometry and uterine artery pulsatility index (UT-PI) and evaluate the performance of screening of this model for all stillbirths and those due to impaired placentation and unexplained or other causes. METHODS: This was a prospective screening study of 70,003 singleton pregnancies including 268 stillbirths, carried out in two phases...
August 18, 2016: Ultrasound in Obstetrics & Gynecology
J J Stirnemann, N Fries, R Bessis, M Fontanges, R Mangione, L J Salomon
OBJECTIVE: To assess potential differences in fetal size between the French population and the international population from the INTERGROWTH-21(st) (IG) project and to measure the impact of switching to the IG references for fetal size. DESIGN AND SETTING: Nationwide cross-sectional study of fetal ultrasound biometry. POPULATION: Low-risk pregnancies prospectively recruited within the network of the national French college of fetal ultrasound over a 6 week-period...
August 12, 2016: Ultrasound in Obstetrics & Gynecology
Lut Geerts, Elrike Van der Merwe, Anneke Theron, Kerry Rademan
OBJECTIVE: To determine the incidence of abnormal multi-vessel Doppler values among advanced pregnancies at risk of suboptimal placentation but with a normal umbilical artery resistance index (RI), and to assess whether clinical and ultrasonography findings can identify them. METHODS: In a prospective cross-sectional study at Tygerberg Hospital, South Africa, women with high-risk pregnancies but normal umbilical artery RI after 32weeks underwent ultrasonography (fetal biometry, liquor, and placenta maturation) and Doppler assessment (uterine, umbilical, and middle cerebral arteries) between February 11 and October 21, 2013...
October 2016: International Journal of Gynaecology and Obstetrics
Borna Poljak, Umber Agarwal, Richard Jackson, Zarko Alfirevic, Andrew Sharp
OBJECTIVE: To define the accuracy of fetal and newborn growth charts for the detection of small for gestational age (SGA) fetuses (<10(th) centile). METHODS: This study was a prospective cohort study performed within a UK specialist fetal growth clinic. 105 consecutive pregnant women referred with a fetus suspected of being SGA. All pregnancies were managed according to a standard protocol using estimated fetal weight (EFW) plotted on customised GROW charts. Last antenatal estimate of EFW (GROW, Mikolayczyk), abdominal circumference (AC Hadlock, Ig-21, AC Chitty) or change in AC over time (POP study) was compared to 4 birthweight charts (GROW, Ig-21, Mikolayczyk, WHO) and to APO...
August 3, 2016: Ultrasound in Obstetrics & Gynecology
Methodius G Tuuli, Kristen Kapalka, George A Macones, Alison G Cahill
OBJECTIVES: The purpose of this study was to test the hypothesis that a formula incorporating 3-dimensional (3D) fractional thigh volume would be superior to the conventional 2-dimensional (2D) formula of Hadlock et al (Am J Obstet Gynecol 1985; 151:333-337) for predicting birth weight and macrosomia. METHODS: We conducted a prospective cohort study of pregnancies complicated by pregestational or gestational diabetes and delivered after 38 weeks. Two-dimensional and 3D sonographic examinations were performed for fetal biometry and factional thigh volumes at 34 to 37 weeks...
September 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Sarah A Valentino, Anne Tarrade, Josiane Aioun, Eve Mourier, Christophe Richard, Michèle Dahirel, Delphine Rousseau-Ralliard, Natalie Fournier, Marie-Christine Aubrière, Marie-Sylvie Lallemand, Sylvaine Camous, Marine Guinot, Madia Charlier, Etienne Aujean, Hala Al Adhami, Paul H Fokkens, Lydiane Agier, John A Boere, Flemming R Cassee, Rémy Slama, Pascale Chavatte-Palmer
BACKGROUND: Airborne pollution is a rising concern in urban areas. Epidemiological studies in humans and animal experiments using rodent models indicate that gestational exposure to airborne pollution, in particular diesel engine exhaust (DE), reduces birth weight, but effects depend on exposure duration, gestational window and nanoparticle (NP) concentration. Our aim was to evaluate the effects of gestational exposure to diluted DE on feto-placental development in a rabbit model. Pregnant females were exposed to diluted (1 mg/m(3)), filtered DE (NP diameter ≈ 69 nm) or clean air (controls) for 2 h/day, 5 days/week by nose-only exposure (total exposure: 20 days in a 31-day gestation)...
2016: Particle and Fibre Toxicology
L Andreoli, G K Bertsias, N Agmon-Levin, S Brown, R Cervera, N Costedoat-Chalumeau, A Doria, R Fischer-Betz, F Forger, M F Moraes-Fontes, M Khamashta, J King, A Lojacono, F Marchiori, P L Meroni, M Mosca, M Motta, M Ostensen, C Pamfil, L Raio, M Schneider, E Svenungsson, M Tektonidou, S Yavuz, D Boumpas, A Tincani
OBJECTIVES: Develop recommendations for women's health issues and family planning in systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS). METHODS: Systematic review of evidence followed by modified Delphi method to compile questions, elicit expert opinions and reach consensus. RESULTS: Family planning should be discussed as early as possible after diagnosis. Most women can have successful pregnancies and measures can be taken to reduce the risks of adverse maternal or fetal outcomes...
July 25, 2016: Annals of the Rheumatic Diseases
M Procházka, P Velebil, T Binder, K Janoušková
UNLABELLED: Fetal macrosomia is associated with an increased risk of perinatal mortality and morbidity for both, mother and fetus. The frequency of these births is between 1.3 to 1.5%. Macrosomic fetuses are defined with a weight of 4500 g and more. Diagnosis and prediction of macrosomia or fetal birth weight is key to determine the tactics of delivery. It is based on the combination and assessment of medical history, clinical parameters and ultrasound biometry. The limit for elective caesarean section is considered the estimated fetal weight in healthy mothers of more than 5000 g...
April 2016: Ceská Gynekologie
Charlotte Oyston, Joanna L Stanley, Mark H Oliver, Frank H Bloomfield, Philip N Baker
Intrauterine growth restriction (IUGR) causes short- and long-term morbidity. Reduced placental perfusion is an important pathogenic component of IUGR; substances that enhance vasodilation in the uterine circulation, such as sildenafil citrate (sildenafil), may improve placental blood flow and fetal growth. This study aimed to examine the effects of sildenafil in the growth-restricted ovine fetus. Ewes carrying singleton pregnancies underwent insertion of vascular catheters, and then, they were randomized to receive uterine artery embolization (IUGR) or to a control group...
September 2016: Hypertension
Tomas Prior, Sailesh Kumar
OBJECTIVE: Maternal hyper-oxygenation has been reported to increase fetal oxygen saturation, and is frequently employed during intra-partum episodes of fetal compromise as a component of in-utero resuscitation. However, there has been little investigation of its influence on fetal haemodynamics, particularly in appropriately grown fetuses. METHODS: This cohort study was undertaken between July 2013 and November 2013. All participants underwent an ultrasound scan prior to active labour (<4cm dilated), during which fetal biometry, umbilical and middle cerebral artery Dopplers were recorded...
July 12, 2016: Journal of Maternal-fetal & Neonatal Medicine
Valérie Briand, Jessica Saal, Caline Ghafari, Bich-Tram Huynh, Nadine Fievet, Christentze Schmiegelow, Achille Massougbodji, Philippe Deloron, Jennifer Zeitlin, Michel Cot
BACKGROUND: Few studies have evaluated the effect of malaria on intrauterine growth restriction on the basis of the fetal growth rate, rather than just the small-for-gestational age z score. Here, we assessed the impact of malaria on IUGR, using data from a longitudinal, ultrasonography-based follow-up study of Beninese women. METHODS: A total of 1016 women were followed up from gestational week 17 to delivery. Malaria was detected every month. Women underwent ultrasonography 4 times for gestational age determination and fetal biometry...
August 1, 2016: Journal of Infectious Diseases
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