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Fetal biometry

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https://www.readbyqxmd.com/read/27900852/association-of-ultrasound-based-measures-of-fetal-body-composition-with-newborn-adiposity
#1
S Ikenoue, F Waffarn, K Sumiyoshi, M Ohashi, C Ikenoue, C Buss, D L Gillen, H N Simhan, S Entringer, P D Wadhwa
BACKGROUND: Newborns exhibit substantial variation in gestational age-adjusted and sex-adjusted fat mass proportion. The antecedent characteristics of fetal body composition that are associated with newborn fat mass proportion are poorly understood. OBJECTIVE: The aim of this study was to determine whether a composite measure of fetal fat mass is prospectively associated with newborn adiposity. METHODS: In a longitudinal study of 109 low-risk pregnancies, fetal ultrasonography was performed at approximately 12, 20 and 30 weeks gestation...
November 29, 2016: Pediatric Obesity
https://www.readbyqxmd.com/read/27885428/normative-biometry-of-the-fetal-brain-using-magnetic-resonance-imaging
#2
Vanessa Kyriakopoulou, Deniz Vatansever, Alice Davidson, Prachi Patkee, Samia Elkommos, Andrew Chew, Miriam Martinez-Biarge, Bibbi Hagberg, Mellisa Damodaram, Joanna Allsop, Matt Fox, Joseph V Hajnal, Mary A Rutherford
The fetal brain shows accelerated growth in the latter half of gestation, and these changes can be captured by 2D and 3D biometry measurements. The aim of this study was to quantify brain growth in normal fetuses using Magnetic Resonance Imaging (MRI) and to produce reference biometry data and a freely available centile calculator ( https://www.developingbrain.co.uk/fetalcentiles/ ). A total of 127 MRI examinations (1.5 T) of fetuses with a normal brain appearance (21-38 gestational weeks) were included in this study...
November 24, 2016: Brain Structure & Function
https://www.readbyqxmd.com/read/27871201/first-trimester-reference-centiles-of-fetal-biometry-in-indian-population
#3
Manisha Kumar, Ravi Vajala, Karuna Sharma, Shalini Singh, Ritu Singh, Usha Gupta, J Bhattacharjee
AIMS AND OBJECTIVE: To create crown- rump length (CRL) based biometric chart for fetus in the first trimester among the Indian population. MATERIAL AND METHODS: Cross sectional data were obtained from 400 singleton pregnancies between 11 - 14 weeks gestation with a normal outcome. Linear regression models were constructed; the mean and standard deviation were derived as a function of CRL. RESULTS: There was a positive correlation of CRL with nuchal translucency (NT) (y = 0...
November 21, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27859800/change-in-maternal-cardiac-output-from-pre-conception-to-mid-pregnancy-is-associated-with-birth-weight-in-healthy-pregnancies
#4
Amita A Mahendru, Fung L Foo, Carmel M McEniery, Thomas R Everett, Ian B Wilkinson, Christoph C Lees
OBJECTIVE: Birth weight (BW) is thought to be determined by maternal health, and genetic, nutritional and placental factors; the latter being influenced by anatomical development and perfusion. Maternal cardiovascular changes contribute to uteroplacental perfusion, however they have not been investigated in relation to fetal growth/BW. Our aim was to explore the relationship between maternal cardiovascular adaptation, fetal growth and BW in healthy pregnancies. METHODS: This was a longitudinal prospective study of women planning to conceive a pregnancy...
November 18, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27858960/lower-accuracy-in-prediction-of-delivery-date-in-stockholm-county-following-introduction-of-new-guidelines
#5
Hans Wessel, Tommy Nyberg
INTRODUCTION: In the Stockholm County new guidelines for predicting the day of delivery was introduced in 2010. Recent clinical use has indicated that the predictive quality might be suboptimal. This study compares the accuracy of three equations applied during the first (crown-rump length (CRL) or bi-parietal diameter (BPD)) and second trimesters (BPD or BPD combined with femur length (FL)). MATERIAL AND METHODS: In 14,239 ultrasound exams the accuracy of estimated delivery date was compared using median deviations from actual birth date, proportion of postterms, births within +/- 7 days of estimated delivery date, accuracy variations depending on fetal size, alternative fetal measurements obtained at the same occasion, and menstrual age...
November 17, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27854395/prediction-of-stillbirth-from-placental-growth-factor-at-19-24-weeks
#6
J E Aupont, R Akolekar, A Illian, S Neonakis, K H Nicolaides
OBJECTIVES: To investigate whether the addition of maternal serum placental growth factor (PlGF) measured at 19-24 weeks' gestation improves the performance of screening for stillbirth that is achieved by a combination of maternal factors, fetal biometry and uterine artery pulsatility index (UtA-PI) and to evaluate the performance of screening with this model for all stillbirths and those due to impaired placentation and unexplained or other causes. METHODS: This was a prospective screening study of 70 003 singleton pregnancies including 268 stillbirths, carried out in two phases...
November 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27854387/prediction-of-stillbirth-from-maternal-factors-fetal-biometry-and-uterine-artery-doppler-at-19-24-weeks
#7
R Akolekar, M Tokunaka, N Ortega, A Syngelaki, K H Nicolaides
OBJECTIVES: To evaluate the performance of screening for all stillbirths and those due to impaired placentation and unexplained or other causes using a combination of maternal factors, fetal biometry and uterine artery pulsatility index (UtA-PI) at 19-24 weeks' gestation and to compare this performance with that of screening by UtA-PI alone. METHODS: This was a prospective screening study of 70 003 singleton pregnancies including 69 735 live births and 268 (0.38%) antepartum stillbirths; 159 (59%) were secondary to impaired placentation and 109 (41%) were due to other or unexplained causes...
November 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27854384/short-term-outcome-of-periviable-small-for-gestational-age-babies-is-our-counseling-up-to-date
#8
A R Lawin-O'Brien, A Dall'Asta, C Knight, S Sankaran, C Scala, A Khalil, A Bhide, S Heggarty, A Rakow, D Pasupathy, A T Papageorghiou, C C Lees
OBJECTIVE: There are limited data for counseling on and management of periviable small-for-gestational-age (SGA) fetuses. We therefore aimed to investigate the short-term outcome of periviable SGA fetuses in relation to the likely underlying cause. METHODS: This was a retrospective study of data from three London tertiary fetal medicine centers obtained between 2000 and 2015. We included viable singleton pregnancies with a severely small fetus, defined as those with an abdominal circumference ≤ 3(rd) percentile, identified between 22 + 0 and 25 + 6 weeks' gestation...
November 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27804212/international-estimated-fetal-weight-standards-of-the-intergrowth-21-st-project
#9
J Stirnemann, J Villar, L J Salomon, E Ohuma, P Ruyan, D G Altman, F Nosten, R Craik, S Munim, L Cheikh Ismail, F C Barros, A Lambert, S Norris, M Carvalho, Y A Jaffer, J A Noble, E Bertino, M G Gravett, M Purwar, C Victora, R Uauy, Z Bhutta, S Kennedy, A T Papageorghiou
BACKGROUND: Estimated fetal weight (EFW) and fetal biometry are complementary measures to screen for fetal growth disturbances. Our aim was to provide international EFW standards to complement the INTERGROWTH-21(st) Fetal Growth Standards that are available for use worldwide. METHODS: Women with an accurate gestational age assessment, who were enrolled in the prospective, international, multicentre, population-based, Fetal Growth Longitudinal Growth Study (FGLS) and INTERBIO-21(st) Fetal Study (FS), two of the components of the INTERGROWTH-21(st) Project, had ultrasound scans every 5 weeks from 9-14 weeks until 40 weeks' gestation...
November 2, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27802270/single-and-serial-fetal-biometry-to-detect-preterm-and-term-small-and-large-for-gestational-age-neonates-a-longitudinal-cohort-study
#10
Adi L Tarca, Edgar Hernandez-Andrade, Hyunyoung Ahn, Maynor Garcia, Zhonghui Xu, Steven J Korzeniewski, Homam Saker, Tinnakorn Chaiworapongsa, Sonia S Hassan, Lami Yeo, Roberto Romero
OBJECTIVES: To assess the value of single and serial fetal biometry for the prediction of small- (SGA) and large-for-gestational-age (LGA) neonates delivered preterm or at term. METHODS: A cohort study of 3,971 women with singleton pregnancies was conducted from the first trimester until delivery with 3,440 pregnancies (17,334 scans) meeting the following inclusion criteria: 1) delivery of a live neonate after 33 gestational weeks and 2) two or more ultrasound examinations with fetal biometry parameters obtained at ≤36 weeks...
2016: PloS One
https://www.readbyqxmd.com/read/27739590/n-acetylcysteine-a-glutathione-precursor-reverts-vascular-dysfunction-and-endothelial-epigenetic-programming-in-intrauterine-growth-restricted-guinea-pigs
#11
Emilio A Herrera, Francisca Cifuentes-Zúñiga, Esteban Figueroa, Cristian Villanueva, Cherie Hernández, René Alegría, Viviana Arroyo-Jousse, Estefania Peñaloza, Marcelo Farías, Ricardo Uauy, Paola Casanello, Bernardo J Krause
KEY POINTS: Intrauterine growth restriction (IUGR) is associated with vascular dysfunction, oxidative stress and signs of endothelial epigenetic programming of the umbilical vessels. There is no evidence that this epigenetic programming is occurring on systemic fetal arteries. In IUGR guinea pigs we studied the functional and epigenetic programming of endothelial nitric oxide synthase (eNOS) (Nos3 gene) in umbilical and systemic fetal arteries, addressing the role of oxidative stress in this process by maternal treatment with N-acetylcysteine (NAC) during the second half of gestation...
October 14, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27706864/maternal-cardiac-function-at-35-37-weeks-gestation-relation-with-birthweight
#12
Gavin P Guy, Hua Z Ling, Mirian Machuca, Liona C Poon, Kypros H Nicolaides
OBJECTIVE: To evaluate the relationship between maternal cardiovascular parameters and neonatal birthweight and examine the potential value of these parameters in improving the prediction of small for gestational age (SGA) and large for gestational age (LGA) neonates provided by maternal characteristics and medical history. METHODS: In 2,835 singleton pregnancies maternal characteristics and medical history were recorded and maternal cardiovascular parameters were measured...
October 5, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27706859/diffusion-magnetic-resonance-imaging-of-the-fetal-brain-in-intrauterine-growth-restriction
#13
Owen J Arthurs, A Rega, F Guimiot, N Belarbi, J Rosenblatt, V Biran, M Elmaleh, G Sebag, M Alison
OBJECTIVES: Diffusion weighted magnetic resonance imaging (DWI) is a sensitive method to assess brain maturation or detect brain lesions, providing Apparent Diffusion Coefficient (ADC) values as a measure of water diffusion. Abnormal ADC values are seen in ischemic brain lesions, such as acute or chronic hypoxia. The aim of this study was to assess whether ADC values in the fetal brain were different in a group of fetuses exposed to severe vascular intrauterine growth restriction, compared to normal controls...
October 5, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27696720/association-of-prenatal-lipid-based-nutritional-supplementation-with-fetal-growth-in-rural-gambia
#14
William Johnson, Momodou K Darboe, Fatou Sosseh, Patrick Nshe, Andrew M Prentice, Sophie E Moore
Prenatal supplementation with protein-energy (PE) and/or multiple-micronutrients (MMNs) may improve fetal growth, but trials of lipid-based nutritional supplements (LNSs) have reported inconsistent results. We conducted a post-hoc analysis of non-primary outcomes in a trial in Gambia, with the aim to test the associations of LNS with fetal growth and explore how efficacy varies depending on nutritional status. The sample comprised 620 pregnant women in an individually randomized, partially blinded trial with four arms: (a) iron and folic acid (FeFol) tablet (usual care, referent group), (b) MMN tablet, (c) PE LNS, and (d) PE + MMN LNS...
October 2, 2016: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/27646438/ep15-10-fetal-biometry-contribution-and-limitations-of-the-three-dimensional-approach
#15
G Ambroise Grandjean, M Chamagne, G Hossu, E Perdriolle-Galet, O Morel
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27627598/commentary-on-impact-of-replacing-chinese-ethnicity-specific-fetal-biometry-charts-by-the-intergrowth-21st-standard
#16
J Zhang
No abstract text is available yet for this article.
September 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27627597/impact-of-replacing-chinese-ethnicity-specific-fetal-biometry-charts-with-the-intergrowth-21-st-standard
#17
Yky Cheng, T Y Leung, Tth Lao, Y M Chan, D S Sahota
OBJECTIVE: To assess the impact of adopting the INTERGROWTH-21(st) biometry standards in a Chinese population. DESIGN: Retrospective cohort study. SETTING: A teaching hospital in Hong Kong. POPULATION: A total of 10 527 Chinese women with a singleton pregnancy having a second- or third-trimester fetal anomaly or growth scan between January 2009 and June 2014. METHODS: Z-scores were derived for fetal abdominal circumference (AC), head circumference (HC), and femur length (FL) using the INTERGROWTH-21(st) and Chinese biometry standards...
September 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27601282/prediction-of-stillbirth-from-maternal-factors-fetal-biometry-and-uterine-artery-doppler-at-19-24-weeks-gestation
#18
Ranjit Akolekar, Mayumi Tokunaka, Nelson Ortega, Argyro Syngelaki, Kypros H Nicolaides
OBJECTIVES: To evaluate the performance of screening for all stillbirths and those due to impaired placentation and unexplained or other causes by a combination of maternal factors, fetal biometry and uterine artery pulsatility index (UT-PI) at 19-24 weeks' gestation and compare this performance to that of screening by UT-PI alone. METHODS: This was a prospective screening study of 70,003 singleton pregnancies including 69,735 live births and 268 (0.38%) antepartum stillbirths; 159 (59%) were secondary to impaired placentation and 109 (41%) were due to other or unexplained causes...
September 7, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27588413/mid-pregnancy-fetal-growth-uteroplacental-doppler-indices-and-maternal-demographic-characteristics-role-in-prediction-of-stillbirth
#19
Alessandra Familiari, Carolina Scala, Maddalena Morlando, Amar Bhide, Asma Khalil, Basky Thilaganathan
INTRODUCTION: To evaluate the relative value of mid trimester fetal growth, uterine artery (UtA) Doppler indices and maternal demographics in prediction of stillbirth. MATERIAL AND METHODS: Retrospective cohort study; 23,894 singleton pregnancies routinely scanned between 19 and 24 weeks' gestation. Maternal characteristics included age, body mass index, ethnicity and medical history. Fetal biometry indices, birthweight and UtA pulsatility index (PI) values were converted to percentiles and multivariable logistic regression analysis was performed...
September 2, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27539237/prediction-of-stillbirth-by-placental-growth-factor-at-19-24-weeks-gestation
#20
Jean Edgard Aupont, Ranjit Akolekar, Aurora Illian, Stratos Neonakis, Kypros H Nicolaides
OBJECTIVES: To investigate whether measurement of maternal serum placental growth factor (PLGF) at 19-24 weeks' gestation improves the performance of screening for stillbirths that is achieved by a combination of maternal factors, fetal biometry and uterine artery pulsatility index (UT-PI) and evaluate the performance of screening of this model for all stillbirths and those due to impaired placentation and unexplained or other causes. METHODS: This was a prospective screening study of 70,003 singleton pregnancies including 268 stillbirths, carried out in two phases...
August 18, 2016: Ultrasound in Obstetrics & Gynecology
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