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Pain, musculoskeletal

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https://www.readbyqxmd.com/read/28315581/morphological-and-physiological-differences-in-the-upper-trapezius-muscle-in-patients-with-work-related-trapezius-myalgia-compared-to-healthy-controls-a-systematic-review
#1
REVIEW
Kayleigh De Meulemeester, Patrick Calders, Robby De Pauw, Ine Grymonpon, Anke Govaerts, Barbara Cagnie
BACKGROUND: Trapezius myalgia is a common musculoskeletal complaint, characterized by pain, stiffness and tightness of the upper trapezius muscle. It is often work-related and caused by prolonged static and repetitive work tasks. It is hypothesized that this leads to various morphological and physiological alterations in muscle tissue but the pathophysiology is poorly understood. These alterations can be investigated by analysing muscle biopsies in order to reveal the underlying cellular mechanisms...
March 6, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28315479/biopsychosocial-influence-on-shoulder-pain-rationale-and-protocol-for-a-pre-clinical-trial
#2
Steven Z George, Roland Staud, Paul A Borsa, Samuel S Wu, Margaret R Wallace, Warren H Greenfield, Lauren N Mackie, Roger B Fillingim
BACKGROUND: Chronic musculoskeletal pain conditions are a prevalent and disabling problem. Preventing chronic musculoskeletal pain requires multifactorial treatment approaches that address its complex etiology. Prior cohort studies identified a high risk subgroup comprised of variation in COMT genotype and pain catastrophizing. This subgroup had increased chance of heightened pain responses (in a pre-clinical model) and higher 12month post-operatives pain intensity ratings (in a clinical model)...
March 14, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28303458/calcitonin-gene-related-peptide-and-pain-a-systematic-review
#3
REVIEW
Wendy Sophie Schou, Sait Ashina, Faisal Mohammad Amin, Peter J Goadsby, Messoud Ashina
BACKGROUND: Calcitonin gene-related peptide (CGRP) is widely distributed in nociceptive pathways in human peripheral and central nervous system and its receptors are also expressed in pain pathways. CGRP is involved in migraine pathophysiology but its role in non-headache pain has not been clarified. METHODS: We performed a systematic literature search on PubMed, Embase and ClinicalTrials.gov for articles on CGRP and non-headache pain covering human studies including experimental studies and randomized clinical trials...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28302054/the-feasibility-of-matching-on-a-propensity-score-for-acupuncture-in-a-prospective-cohort-study-of-patients-with-chronic-pain
#4
Eric S Johnson, John F Dickerson, William M Vollmer, Alee M Rowley, Cheryl Ritenbaugh, Richard A Deyo, Lynn DeBar
BACKGROUND: Propensity scores are typically applied in retrospective cohort studies. We describe the feasibility of matching on a propensity score derived from a retrospective cohort and subsequently applied in a prospective cohort study of patients with chronic musculoskeletal pain before the start of acupuncture or usual care treatment and enrollment in a comparative effectiveness study that required patient reported pain outcomes. METHODS: We assembled a retrospective cohort study using data from 2010 to develop a propensity score for acupuncture versus usual care based on electronic healthcare record and administrative data (e...
March 16, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28299312/genetic-screening-of-mutations-associated-with-fabry-disease-in-a-nationwide-cohort-of-juvenile-idiopathic-arthritis-patients
#5
Maria J Gonçalves, Ana F Mourão, António Martinho, Olívia Simões, José Melo-Gomes, Manuel Salgado, Paula Estanqueiro, Célia Ribeiro, Iva Brito, João E Fonseca, Helena Canhão
Fabry's disease (FD) is a lysosomal storage disorder associated with an alpha-galactosidase A deficiency. The prevalence of FD among juvenile idiopathic arthritis (JIA) patients with established diagnosis is unknown, but as musculoskeletal pain may be an important complaint at presentation, misdiagnosed cases are anticipated. With this study, we aim to calculate the frequency of FD-associated mutations in a cohort of JIA patients. Children with JIA from a national cohort were selected. Clinical and laboratorial information was recorded in the Portuguese rheumatic diseases register (http://Reuma...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28299231/chronic-osteoporotic-pain-in-mice-cutaneous-and-deep-musculoskeletal-pain-are-partially-independent-of-bone-resorption-and-differentially-sensitive-to-pharmacological-interventions
#6
Miyako Suzuki, Magali Millecamps, Lina Naso, Seiji Ohtori, Chisato Mori, Laura S Stone
Although the pathological changes in osteoporotic bones are well established, the characterization of the osteoporotic pain and its appropriate treatment are not fully elucidated. We investigated the behavioral signs of cutaneous and deep musculoskeletal pain and physical function; time-dependent changes in bone mineral density (BMD) and the emergence of the behavioral phenotype; and the effects of pharmacological interventions having different mechanisms of action (chronic intraperitoneal administration of pamidronate [0...
2017: Journal of Osteoporosis
https://www.readbyqxmd.com/read/28298416/trajectories-of-multisite-musculoskeletal-pain-and-implications-for-prevention
#7
EDITORIAL
David Coggon, Georgia Ntani
No abstract text is available yet for this article.
March 15, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28297577/surgical-excision-of-heterotopic-ossification-leads-to-re-emergence-of-mesenchymal-stem-cell-populations-responsible-for-recurrence
#8
Shailesh Agarwal, Shawn Loder, David Cholok, John Li, Chris Breuler, James Drake, Cameron Brownley, Joshua Peterson, Shuli Li, Benjamin Levi
Trauma-induced heterotopic ossification (HO) occurs after severe musculoskeletal injuries and burns, and presents a significant barrier to patient rehabilitation. Interestingly, the incidence of HO significantly increases with repeated operations and after resection of previous HO. Treatment of established heterotopic ossification is challenging because surgical excision is often incomplete, with evidence of persistent heterotopic bone. As a result, patients may continue to report the signs or symptoms of HO, including chronic pain, nonhealing wounds, and joint restriction...
March 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28296137/percutaneous-peripheral-nerve-stimulation-for-the-treatment-of-chronic-low-back-pain-two-clinical-case-reports-of-sustained-pain-relief
#9
Leonardo Kapural, Christopher A Gilmore, John Chae, Richard L Rauck, Steven P Cohen, Michael F Saulino, Amorn Wongsarnpigoon, Meredith J McGee, Joseph W Boggs
As the leading cause of disability among U.S. adults, chronic low back pain (LBP) is one sof the most prevalent and challenging musculoskeletal conditions. Neuromodulation provides an opportunity to reduce or eliminate the use of opioids to treat chronic LBP, but the cost and invasiveness of existing methods have limited its broad adoption, especially earlier in the treatment continuum. The present case report details the results of a novel method of short-term percutaneous peripheral nerve stimulation (PNS) in 2 subjects with chronic LBP...
March 14, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28291448/reliability-responsiveness-and-criterion-validity-of-the-kiio-sensor-a-new-tool-for-assessment-of-muscle-function
#10
Patrick Grabowski, Michelle Narveson, Stephen Siegle
Musculoskeletal injuries are a leading cause of disability in both the general population and military, and the ability to effectively quantify musculoskeletal function remains problematic. The aim of the current study is to investigate the reliability, responsiveness, and criterion validity of the kiio Sensor for measurement of muscle strength, a key aspect of comprehensive functional assessment. Forty-four (24 male, 20 female) physically active civilian adults (mean [SD] = 21.2 [1.5] years of age) with no history of upper extremity injuries in the last year and no current complaints of pain, weakness, or functional limitation completed two sessions of maximum shoulder external rotation contractions...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290947/widespread-use-of-prescription-nonsteroidal-anti-inflammatory-drugs-among-u-s-army-active-duty-soldiers
#11
Leila A Walker, Edward J Zambraski, Roger F Williams
INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain and inflammation by inhibiting prostaglandin synthesis. There is a high incidence of musculoskeletal injuries in the military, which would validate the widespread use of NSAIDs. This study determined the amount and specific types of NSAIDs being prescribed to U.S. Army active duty soldiers. METHODS AND MATERIALS: This study was a quantitative study which utilized an existing database of de-identified data; therefore, institutional review board approval was not required...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290757/hip-musculoskeletal-conditions-and-associated-factors-that-influence-squat-performance-a-systematic-review
#12
Scott W Cheatham, Kyle R Stull, Mike Fantigrassi, Ian Montel
CONTEXT: The squat is a fundamental movement for weight lifting and sports performance. Both unilateral and bilateral squats are also used to assess transitional and dynamic lower extremity control. Common lower extremity conditions can have an influence on squat performance. Of interest, are the effects of hip musculoskeletal conditions and associated factors such as hip muscle pain, fatigue, and tightness on squat performance. Currently, there has been no appraisal of the evidence regarding the association of these conditions and associated factors on squat performance...
March 14, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28289747/physiotherapy-treatments-in-musculoskeletal-pathologies-associated-with-haemophilia-a-literature-review
#13
Jesús Guodemar-Pérez, Montserrat Ruiz-López, Elena Rodríguez-López, Pablo García-Fernández, Juan Pablo Hervás-Pérez
The aim of this study is to offer physiotherapists a synthesis of the main therapeutic tools available for the treatment of musculoskeletal pathologies in patients with haemophilia, according to the scientific literature. Although bleeds are recognised as no longer being a cause of death for people with haemophilia, the accompanying musculoskeletal injuries now represent the main problem associated with this disorder. There is a lack of clear guidelines to date regarding the physiotherapy treatment of these disorders...
March 14, 2017: Hämostaseologie
https://www.readbyqxmd.com/read/28288602/is-being-a-regular-player-with-fewer-teammates-associated-with-musculoskeletal-pain-in-youth-team-sports-a-cross-sectional-study
#14
Takafumi Abe, Masamitsu Kamada, Jun Kitayuguchi, Shinpei Okada, Yoshiteru Mutoh, Yuji Uchio
BACKGROUND: Musculoskeletal pain (MSP) is a commonly reported symptom in youth sports players. Some sports-related risk factors have been reported, but previous studies on extrinsic risk factors did not focus on management of team members (e.g., regular or non-regular players, number of players) for reducing sports-related MSP. This study aimed to examine the association of playing status (regular or non-regular players) and team status (fewer or more teammates) with MSP in youth team sports...
March 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28287924/individual-and-work-related-risk-factors-for-musculoskeletal-pain-among-computer-workers-in-nigeria
#15
Ukachukwu Okoroafor Abaraogu, Paschal Nzubechukwu Okorie, Deborah Onyinyechukwu Duru, Elochukwu Fortune Ezenwankwo
We investigated the prevalence of musculoskeletal pain, MSP and the association of one month prevalence with individual and work-related factors among commercial typists in Enugu. Participants responded to a questionnaire about occurrences of MSP and 75.6% (242/320)response rate was achieved. Prevalence was summarized in frequencies and percentages while associations between MSPs and risk factors were explored using Chi-square. MSP was most common in the low back (58.3%), and low back pain limited 51.7% from activities between 1-30 days...
March 13, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/28287775/musculoskeletal-complaints-anxiety-depression-symptoms-and-neuroticism-a-study-of-middle-aged-twins
#16
Olav Vassend, Espen Røysamb, Christopher Sivert Nielsen, Nikolai Olavi Czajkowski
BACKGROUND: Musculoskeletal (MS) complaints are reported commonly, but the extent to which such complaints reflect the severity of site-specific pathology or a more generalized susceptibility to feel pain/discomfort is uncertain. Both site-specific and more widespread MS conditions have been shown to be linked to anxiety and depression, but the nature of this relationship is poorly understood. In the present study the role of neuroticism as a shared risk factor that may possibly explain the co-occurrence between anxiety-depression and MS complaints was investigated...
March 13, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28286331/stems-pilot-trial-a-pilot-cluster-randomised-controlled-trial-to-investigate-the-addition-of-patient-direct-access-to-physiotherapy-to-usual-gp-led-primary-care-for-adults-with-musculoskeletal-pain
#17
Annette Bishop, Reuben O Ogollah, Sue Jowett, Jesse Kigozi, Stephanie Tooth, Joanne Protheroe, Elaine M Hay, Chris Salisbury, Nadine E Foster
INTRODUCTION: Around 17% of general practitioner (GP) consultations are for musculoskeletal conditions, which will rise as the population ages. Patient direct access to physiotherapy provides one solution, yet adoption in the National Health Service (NHS) has been slow. SETTING: A pilot, pragmatic, non-inferiority, cluster randomised controlled trial (RCT) in general practice and physiotherapy services in the UK. OBJECTIVES: Investigate feasibility of a main RCT...
March 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28284771/prevalence-of-musculoskeletal-manifestations-and-related-disabilities-in-a-peruvian-urban-population-living-at-high-altitude-copcord-study-stage-i
#18
Oscar Vega-Hinojosa, Mario H Cardiel, Pilar Ochoa-Miranda
OBJECTIVE: Estimate the prevalence of musculoskeletal manifestations and related disabilities of an urban population living at high altitude in Juliaca, Puno, Peru, using the Community Oriented Program for Control of Rheumatic Diseases (COPCORD) questionnaire and Health Assessment Questionnaire (HAQ) disability index. METHODS: A cross-sectional study was performed in a sample of 1095 people. In each interview, the COPCORD methodology and the HAQ were applied. The city was divided into 8 sectors...
March 8, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28284228/interactive-wearable-systems-for-upper-body-rehabilitation-a-systematic-review
#19
REVIEW
Qi Wang, Panos Markopoulos, Bin Yu, Wei Chen, Annick Timmermans
BACKGROUND: The development of interactive rehabilitation technologies which rely on wearable-sensing for upper body rehabilitation is attracting increasing research interest. This paper reviews related research with the aim: 1) To inventory and classify interactive wearable systems for movement and posture monitoring during upper body rehabilitation, regarding the sensing technology, system measurements and feedback conditions; 2) To gauge the wearability of the wearable systems; 3) To inventory the availability of clinical evidence supporting the effectiveness of related technologies...
March 11, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28283340/a-prospective-randomized-double-dummy-trial-comparing-intravenous-push-dose-of-low-dose-ketamine-to-short-infusion-of-low-dose-ketamine-for-treatment-of-moderate-to-severe-pain-in-the-emergency-department
#20
Sergey Motov, Mo Mai, Illya Pushkar, Antonios Likourezos, Jefferson Drapkin, Matthew Yasavolian, Jason Brady, Peter Homel, Christian Fromm
STUDY OBJECTIVE: Compare adverse effects and analgesic efficacy of low-dose ketamine for acute pain in the ED administered either by single intravenous push (IVP) or short infusion (SI). METHODS: Patients 18-65, presenting to ED with acute abdominal, flank, or musculoskeletal pain with initial pain score≥5, were randomized to ketamine 0.3mg/kg by either IVP or SI with placebo double-dummy. Adverse effects were evaluated by Side Effects Rating Scale for Dissociative Anesthetics (SERSDA) and Richmond Agitation-Sedation Scale (RASS) at 5, 15, 30, 60, 90, and 120min post-administration; analgesic efficacy was evaluated by Numerical Rating Scale (NRS)...
March 3, 2017: American Journal of Emergency Medicine
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