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https://www.readbyqxmd.com/read/28228898/disseminated-coccidioidomycosis-with-multifocal-musculoskeletal-disease-involvement
#1
Michael F McConnell, Ann Shi, Todd M Lasco, Luke Yoon
We report a rare case of disseminated coccidioidomycosis with multifocal musculoskeletal involvement. The patient presented to the emergency department with left shoulder pain and swelling. Magnetic resonance imaging of the left shoulder revealed enhancing soft tissue masses, bony lesions, and fluid collections in and around the glenohumeral joint with involvement of the proximal humerus, glenoid, and rotator cuff musculature. Multiple additional areas of involvement were subsequently discovered. Fungal cultures confirmed coccidioidomycosis infection at all surgical sites with superimposed polymicrobial bacterial infection in the left shoulder...
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28228701/chiropractic-management-of-a-patient-with-thoracic-pain-and-a-stable-thoracic-aortic-aneurysm-a-case-report
#2
Shawn M Neff, Casey S Okamoto
OBJECTIVE: The purpose of this case report was to describe chiropractic management of thoracic pain in a patient with a stable thoracic aortic aneurysm. CLINICAL FEATURES: An 89-year-old man presented with axial mid- and upper back pain localized predominantly at the T8 and T1 spinal segmental levels. A review of available imaging revealed a stable aneurysmal dilatation of the ascending aorta, which measured 4.3 cm. INTERVENTION AND OUTCOME: Because the thoracic pain was musculoskeletal in nature and the thoracic aortic aneurysm was stable, mechanical manipulation was provided using the Impulse adjusting instrument...
March 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/28225991/prevalence-of-musculoskeletal-symptoms-in-obese-patients-candidates-for-bariatric-surgery-and-its-impact-on-health-related-quality-of-life
#3
Gabriela Calenzani, Fabiana Ferreira Dos Santos, Veronica Lourenço Wittmer, Grace Kelly Filgueiras Freitas, Flávia Marini Paro
Objective: This study was designed to identify the major musculoskeletal symptoms of individuals with obesity, to assess their health-related quality of life, and to evaluate the correlation between the musculoskeletal symptoms and the individuals' health-related quality of life. Materials and methods: Cross-sectional study. Instruments used: "Nordic Musculoskeletal Questionnaire" and "The Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36)"...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28224704/advanced-glycation-end-products-regulate-anabolic-and-catabolic-activities-via-nlrp3-inflammasome-activation-in-human-nucleus-pulposus-cells
#4
Yu Song, Yan Wang, Yukun Zhang, Wen Geng, Wei Liu, Yong Gao, Shuai Li, Kun Wang, Xinghuo Wu, Liang Kang, Cao Yang
Intervertebral disc degeneration is widely recognized as a cause of lower back pain, neurological dysfunction and other musculoskeletal disorders. The major inflammatory cytokine IL-1β is associated with intervertebral disc degeneration; however, the molecular mechanisms that drive IL-1β production in the intervertebral disc, especially in nucleus pulposus (NP) cells, are unknown. In some tissues, advanced glycation end products (AGEs), which accumulate in NP tissues and promote its degeneration, increase oxidative stress and IL-1β secretion, resulting in disorders, such as obesity, diabetes mellitus and ageing...
February 22, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28224415/effectiveness-of-workplace-interventions-in-return-to-work-for-musculoskeletal-pain-related-and-mental-health-conditions-an-update-of-the-evidence-and-messages-for-practitioners
#5
REVIEW
K L Cullen, E Irvin, A Collie, F Clay, U Gensby, P A Jennings, S Hogg-Johnson, V Kristman, M Laberge, D McKenzie, S Newnam, A Palagyi, R Ruseckaite, D M Sheppard, S Shourie, I Steenstra, D Van Eerd, B C Amick
Purpose The objective of this systematic review was to synthesize evidence on the effectiveness of workplace-based return-to-work (RTW) interventions and work disability management (DM) interventions that assist workers with musculoskeletal (MSK) and pain-related conditions and mental health (MH) conditions with RTW. Methods We followed a systematic review process developed by the Institute for Work & Health and an adapted best evidence synthesis that ranked evidence as strong, moderate, limited, or insufficient...
February 21, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28224414/does-the-length-of-disability-between-injury-and-functional-restoration-program-entry-affect-treatment-outcomes-for-patients-with-chronic-disabling-occupational-musculoskeletal-disorders
#6
Sali Asih, Randy Neblett, Tom G Mayer, Robert J Gatchel
Purpose Functional restoration programs (FRPs), for patients with chronic disabling occupational musculoskeletal disorders (CDOMDs), have consistently demonstrated positive socioeconomic treatment outcomes, including decreased psychosocial distress and increased work return. The pre-treatment length of disability (LOD), or time between injury and treatment admission, has been shown to influence FRP work outcomes. Some studies have found that shorter LOD is associated with better work outcomes. However, few studies have actually examined cohorts with LOD duration longer than 18 months...
February 21, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28222988/thirty-day-and-90-day-hospital-readmission-after-outpatient-upper-extremity-hemodialysis-access-creation
#7
Jeffrey J Siracuse, Nishant K Shah, Matthew R Peacock, Georges Tahhan, Jeffrey A Kalish, Denis Rybin, Mohammad H Eslami, Alik Farber
OBJECTIVE: Patients with end-stage renal disease have multiple comorbidities and are at increased risk for postoperative complications and resource utilization. Our goal was to determine the rate and causes of 30-day and 90-day hospital readmissions after the creation of outpatient hemodialysis access. METHODS: We retrospectively reviewed all outpatient upper extremity hemodialysis access creations performed at our medical center from 2008 to 2015. Readmission was defined as any inpatient status admission ≤30 and 90 days...
February 17, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28222918/receipt-of-pain-management-information-preoperatively-is-associated-with-improved-functional-gain-after-elective-total-joint-arthroplasty
#8
Celeste A Lemay, Courtland G Lewis, Jasvinder A Singh, Patricia D Franklin
BACKGROUND: Poorly controlled postoperative pain may adversely affect total joint arthroplasty (TJA) patients' outcomes and associated healthcare cost. Understanding effective pain management after surgery is important to patients, surgeons, and hospitals. We evaluated patient-reported receipt of preoperative pain management information in a national prospective cohort evaluating postoperative pain and function following elective TJA. METHODS: Preoperative and 2-week and 6-month postoperative survey data of 1609 TJA patients collected between June 2013 and December 2014 were analyzed...
January 26, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28222707/comparison-of-the-swedish-start-back-screening-tool-and-the-short-form-of-the-%C3%A3-rebro-musculoskeletal-pain-screening-questionnaire-in-patients-with-acute-or-subacute-back-and-neck-pain
#9
Malin Forsbrand, Birgitta Grahn, Jonathan C Hill, Ingemar F Petersson, Charlotte Post Sennehed, Kjerstin Stigmar
BACKGROUND: Patients with back and neck pain are often seen in primary care and it is important to provide them with tailored interventions based on risk stratification/triage. The STarT Back Screening Tool (SBT) is a widely used screening questionnaire which has not yet been validated for a population with back and/or neck pain with short duration. Our aim was to compare the concurrent validity of the SBT and the short form of the ÖMPSQ including psychometric properties and clinical utility in a primary care setting...
February 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28222382/corporeal-illusions-in-chronic-spinal-cord-injuries
#10
Michele Scandola, Salvatore Maria Aglioti, Renato Avesani, Gianettore Bertagnoni, Anna Marangoni, Valentina Moro
While several studies have investigated corporeal illusions in patients who have suffered from a stroke or undergone an amputation, only anecdotal or single case reports have explored this phenomenon after spinal cord injury. Here we examine various different types of bodily misperceptions in a comparatively large group of 49 people with spinal cord injury in the post-acute and chronic phases after the traumatic lesion onset. An extensive battery of questionnaires concerning a variety of body related feelings was administered and the results were correlated to the main clinical variables...
February 17, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28221316/a-66-year-old-man-with-neck-pain
#11
Dayna Jaynstein
Neck pain is a fairly common complaint among patients in the ED. The differential diagnosis is broad, from musculoskeletal causes to potentially life-threatening causes. Providers need to have a good understanding of when the complaint of neck pain requires more diagnostic investigation, even in a patient with chronic neck pain.
March 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28221285/genome-wide-methylation-analysis-of-a-large-population-sample-shows-neurological-pathways-involvement-in-chronic-widespread-musculoskeletal-pain-cwp
#12
Gregory Livshits, Ida Malkin, Maxim B Freidin, Yudong Xia, Fei Gao, Jun Wang, Timothy D Spector, Alex MacGregor, Jordana T Bell, Frances Mk Williams
Chronic widespread musculoskeletal pain (CWP), has a considerable heritable component, which remains to be explained. Epigenetic factors may contribute to and account for some of the heritability estimate. We analysed epigenome-wide methylation using MeDIPseq in whole blood DNA from 1708 monozygotic (MZ) and dizygotic (DZ) Caucasian twins having CWP prevalence of 19.9%. Longitudinally stable methylation bins (lsBINs), were established by testing repeated measurements conducted ≥3 years apart, n=292. DNA methylation variation at lsBINs was tested for association with CWP in a discovery set of 50 MZ twin pairs discordant for CWP, and in an independent dataset (n=1608 twins), and the results from the two samples were combined using Fisher's method...
February 15, 2017: Pain
https://www.readbyqxmd.com/read/28220911/national-survey-of-health-in-the-tattoo-industry-observational-study-of-448-french-tattooists
#13
Nicolas Kluger
OBJECTIVES: The data regarding the health of professional tattooists is inexistent. Tattooists are usually heavily tattooed and exposed daily to body fluids and skin-to-skin contacts with customers, tattoo inks, solvents, allergens, irritants, and work for hours often in inadequate positions using vibrating tattoo machines. We analyzed the health status of active French professional tattooists. MATERIAL AND METHODS: An observational self-reported Internet survey was performed among 448 tattooists who were members of the French Tattoo Union in November 2013...
February 21, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28220607/neurological-and-spinal-manifestations-of-the-ehlers-danlos-syndromes
#14
Fraser C Henderson, Claudiu Austin, Edward Benzel, Paolo Bolognese, Richard Ellenbogen, Clair A Francomano, Candace Ireton, Petra Klinge, Myles Koby, Donlin Long, Sunil Patel, Eric L Singman, Nicol C Voermans
The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders characterized by joint hypermobility, skin extensibility, and tissue fragility. This communication briefly reports upon the neurological manifestations that arise including the weakness of the ligaments of the craniocervical junction and spine, early disc degeneration, and the weakness of the epineurium and perineurium surrounding peripheral nerves. Entrapment, deformation, and biophysical deformative stresses exerted upon the nervous system may alter gene expression, neuronal function and phenotypic expression...
February 21, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28218239/treatment-free-remission-following-frontline-nilotinib-in-patients-with-chronic-myeloid-leukemia-in-chronic-phase-results-from-the-enestfreedom-study
#15
A Hochhaus, T Masszi, F J Giles, J P Radich, D M Ross, M T G Casares, A Hellmann, J Stentoft, E Conneally, V García-Gutiérrez, N Gattermann, W Wiktor-Jedrzejczak, P D le Coutre, B Martino, S Saussele, H D Menssen, W Deng, N Krunic, V Bedoucha, G Saglio
The single-arm, phase 2 ENESTfreedom trial (ClinicalTrials.gov, NCT01784068) assessed the potential for treatment-free remission (TFR; ie, the ability to maintain a molecular response after stopping therapy) following frontline nilotinib treatment. Patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase (CML-CP) with MR(4.5) (BCR-ABL1⩽0.0032% on the International Scale; BCR-ABL1(IS)) and ⩾2 years of frontline nilotinib therapy were enrolled. Patients with sustained deep molecular response during the 1-year nilotinib consolidation phase were eligible to stop treatment and enter the TFR phase...
February 20, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/28216207/musculoskeletal-pain-and-occupational-variables-in-teachers-with-voice-disorders-and-in-those-with-healthy-voices-a-pilot-study
#16
Jhonatan da Silva Vitor, Larissa Thaís Donalonso Siqueira, Vanessa Veis Ribeiro, Janine Santos Ramos, Alcione Ghedini Brasolotto, Kelly Cristina Alves Silverio
PURPOSE: This study aimed to compare musculoskeletal pain perception in teachers with voice disorders and in those with healthy voices, and to investigate the relationship between musculoskeletal pain and occupational variables (ie, work journey per week and working period). METHOD: Forty-three classroom teachers were divided into two groups: dysphonic group (DG), 32 classroom teachers with voice complaints and voice disorders; and non-DG, 11 classroom teachers without voice complaints and who are vocally healthy...
February 16, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28215603/a-new-concept-for-an-old-pain-carpalgia-pain-in-the-wrist
#17
L Maizo Alemán
OBJECTIVE: The idea of this article is to propose to the general use of a new term to semiologically describe musculoskeletal wrist pain. FINDINGS: The use of terms with Greco-Latin roots is common in the medical field. The result is expressed in the newly coined word (neologism) "carpalgia", defined as musculoskeletal pain in the region of the wrist. CONCLUSIONS: The use of other terms related to musculoskeletal pain of the shoulder (omalgia), knee (gonalgia), metatarsus (metatarsalgia), spine (cervicalgia, lumbalgia), or hip (coxalgia) terms have demonstrated their importance through their applicability in different medical journals in recent years...
February 15, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28214616/exploring-factors-influencing-low-back-pain-in-people-with-non-dysvascular-lower-limb-amputation-a-national-survey
#18
Hemakumar Devan, Paul Hendrick, Leigh Hale, Allan Carman, Michael P Dillon, Daniel Cury Ribeiro
BACKGROUND: Chronic low back pain (LBP) is a common musculoskeletal impairment in people with lower limb amputation. Given the multifactorial nature of LBP, exploring the factors influencing the presence and intensity of LBP is warranted. OBJECTIVE: To investigate which physical, personal, and amputee-specific factors predicted presence and intensity of low back pain (LBP) in persons with non-dysvascular transfemoral (TFA) and transtibial amputation (TTA). DESIGN: A retrospective cross-sectional survey SETTING: A national random sample of people with non-dysvascular TFA and TTA...
February 15, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28212666/classical-hodgkin-lymphoma-masquerading-as-chronic-recurrent-multifocal-osteomyelitis-a-case-report
#19
Michael Pham, Steven Ressler, Allison Rosenthal, Katalin Kelemen
BACKGROUND: Hodgkin lymphoma is a hematologic malignancy usually confined to lymphatic structures and commonly associated with constitutional symptoms. Bony involvement and musculoskeletal symptoms are uncommon and typically seen in advanced disease. In this case, we report an unusual presentation of classical Hodgkin lymphoma and highlight diagnostic challenges leading to the misdiagnosis and treatment as chronic recurrent multifocal osteomyelitis. CASE PRESENTATION: A 38-year-old white man presented with lower extremity musculoskeletal pain...
February 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28211842/assessment-of-upper-limb-musculoskeletal-pain-and-posture-in-workers-of-packaging-units-of-pharmaceutical-industries
#20
Yasser Labbafinejad, Hossein Danesh, Zahra Imanizade
BACKGROUND: Work-related musculoskeletal disorders are defined as the disabling or painful injury to the muscles, nerves or tendons that are caused by work or aggravated by it. Some studies confirm the association between working in packaging units in various industries and the pain in the upper limb, but also there are controversies about the possible risk factors among different working populations. OBJECTIVE: The present study aims to define the potential ergonomic risk factors for musculoskeletal pain in the upper limb...
February 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
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