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https://www.readbyqxmd.com/read/30004358/maternal-near-miss-audit-in-the-metro-west-maternity-service-cape-town-south-africa-a-retrospective-observational-study
#1
I A Iwuh, S Fawcus, L Schoeman
BACKGROUND: A maternal near-miss is defined as a life-threatening pregnancy-related complication where the woman survives. The World Health Organization (WHO) has produced a tool for identifying near-misses according to criteria that include the occurrence of a severe maternal complication together with organ dysfunction and/or specified critical interventions. Maternal deaths have been audited in the public sector Metro West maternity service in Cape Town, South Africa, for many years, but there has been no monitoring of near-misses...
February 27, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/30004347/striking-increase-in-the-incidence-of-infective-endocarditis-associated-with-recreational-drug-abuse-in-urban-south-africa
#2
R Meel, M R Essop
BACKGROUND: We have recently noted a dramatic rise in the number of patients with infective endocarditis (IE) related to intravenous (IV) nyaope (a mixture of heroin, cocaine and antiretroviral drugs) presenting to Chris Hani Baragwanath Academic Hospital in Johannesburg, South Africa. OBJECTIVES: To document the clinical and echocardiographic characteristics of these patients. METHODS: Clinical and echocardiographic characteristics of all patients (N=68) with IE due to IV nyaope use were retrospectively extracted from hospital records (December 2014 - February 2017)...
June 26, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/30002931/magnesium-supplementation-and-blood-pressure-in-pregnancy-a-double-blind-randomized-multicenter-study
#3
Maria Bullarbo, Helena Mattson, Anna-Karin Broman, Natalia Ödman, Thorkild F Nielsen
Objective: To investigate the effect of magnesium (Mg) supplementation in healthy pregnant women for prevention of blood pressure increase. Secondary outcomes were comparison of biomarkers for hypertensive disorders and labour and fetal outcomes between the groups. Methods: Two hundred nulliparous healthy pregnant women were double-blind randomized to receive Mg daily or placebo. Results: There were no differences in blood pressure increase...
2018: Journal of Pregnancy
https://www.readbyqxmd.com/read/30002694/standardised-tomato-extract-as-an-alternative-to-acetylsalicylic-acid-in-patients-with-primary-hypertension-and-high-cardiovascular-risk-a-randomised-controlled-trial
#4
Beata Krasinska, Angelika Osińska, Maciej Osinski, Aleksandra Krasinska, Piotr Rzymski, Andrzej Tykarski, Zbigniew Krasiński
Introduction: Cardiovascular (CV) diseases remain a leading global cause of death. It has been proven that the use of acetylsalicylic acid (ASA) in secondary prevention reduces the CV risk, while the benefits of ASA in primary prevention have recently been debated. The aim of the study was to compare the antiplatelet effect of standardised tomato extract (STE) and ASA in hypertensive patients with high CV risk. Material and methods: The study involved high-risk patients with arterial hypertension (AH) randomly assigned to one of two groups: group 1 included 33 patients receiving ASA and group 2 included 32 patients receiving STE...
June 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/30002677/investigation-of-geriatric-patients-with-abdominal-pain-admitted-to-emergency-department
#5
Pınar Henden Çam, Ahmet Baydin, Savaş Yürüker, Ali Kemal Erenler, Erdinç Şengüldür
Introduction: The aim of this study is to detect the possible reasons of abdominal pain in the patients aged 65 and older admitted to emergency department (ED) with complaint of abdominal pain which is not related to trauma, to determine the length of hospitalization of old (65-75 age) and elderly (aged 75 and older) patients, and to define the hospitalization and mortality rates. Material and Methods: In the study, 336 patients were included. Groups were compared in respect to gender, internal or surgical prediagnoses, complaints accompanying abdominal pain, vital findings, comorbidities, requested consultations, hospitalizing service, waiting time in the ED and in the hospital, and treatment methods...
2018: Current Gerontology and Geriatrics Research
https://www.readbyqxmd.com/read/30002140/adapting-and-evaluating-a-health-system-intervention-from-kaiser-permanente-to-improve-hypertension-management-and-control-in-a-large-network-of-safety-net-clinics
#6
Valy Fontil, Reena Gupta, Nathalie Moise, Ellen Chen, David Guzman, Charles E McCulloch, Kirsten Bibbins-Domingo
BACKGROUND: Nearly half of Americans with diagnosed hypertension have uncontrolled blood pressure (BP) while some integrated healthcare systems, such as Kaiser Permanente Northern California, have achieved control rates upwards 90%. METHODS AND RESULTS: We adapted Kaiser Permanente's evidence-based treatment protocols in a racially and ethnically diverse population at 12 safety-net clinics in the San Francisco Health Network. The intervention consisted of 4 elements: a hypertension registry, a simplified treatment intensification protocol that included fixed-dose combination medications containing diuretics, standardized BP measurement protocol, and BP check visits led by registered nurse and pharmacist staff...
July 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/30001957/uhl-s-disease-a-rare-disease-with-an-uncommon-presentation
#7
Sílvia Aguiar Rosa, Ana Figueiredo Agapito, Marta António, Lídia de Sousa, José Alberto Oliveira, Sérgio Laranjo, Susana Martins, Nuno Jalles Tavares, Fátima F Pinto, Rui Cruz Ferreira
Uhl's anomaly is a rare disease secondary to the selective but uncontrolled apoptosis of right ventricular myocytes during the perinatal period, following complete cardiac development. This explains the absence of the right ventricular myocardium and the direct apposition of endocardium to epicardium without a myocardial layer in between, resulting in right ventricular failure. This paper describes a case of Uhl's disease with an uncommon presentation. A 28-year-old man was admitted with dyspnea and cyanosis...
July 9, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29998803/extracranial-to-intracranial-bypass-for-pressor-dependent-cerebrovascular-insufficiency-modified-classification-and-representative-case
#8
Daniel M Heiferman, John R Souter, Matthew R Reynolds, Douglas E Anderson, Joseph C Serrone
BACKGROUND: While some randomized clinical trials have reduced the indications for cerebral revascularization in the secondary prevention of ischemic stroke, a distinct subset of patients with blood pressure augmentation dependent cerebrovascular insufficiency due to large vessel occlusions remains unaddressed. With the recent paradigm shifts in acute ischemic stroke care, the role of extracranial to intracranial (EC-IC) bypass must be re-addressed when endovascular intervention is not a feasible option...
July 12, 2018: Current Neurovascular Research
https://www.readbyqxmd.com/read/29998426/intracerebral-hemorrhage-in-women-a-review-with-special-attention-to-pregnancy-and-the-post-partum-period
#9
REVIEW
Shahed Toossi, Asma M Moheet
Non-traumatic intracranial hemorrhage includes subarachnoid hemorrhage, subdural hemorrhage, and intracerebral hemorrhage (ICH), which can be classified as primary or secondary. Primary ICH is due to arterial hypertension or cerebral amyloid angiopathy, and secondary ICH is due to cerebral vascular malformations, coagulopathies, infectious complications, brain tumors, and illicit stimulant drug use. This review explores the epidemiology and management of non-traumatic ICH in women, with a focus on pregnancy and the post-partum period, defined as 6 weeks post-delivery...
July 11, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29997518/impaired-myofilament-contraction-drives-right-ventricular-failure-secondary-to-pressure-overload-model-simulations-experimental-validation-and-treatment-predictions
#10
Jennifer L Philip, Ryan J Pewowaruk, Claire S Chen, Diana M Tabima, Daniel A Beard, Anthony J Baker, Naomi C Chesler
Introduction: Pulmonary hypertension (PH) causes pressure overload leading to right ventricular failure (RVF). Myocardial structure and myocyte mechanics are altered in RVF but the direct impact of these cellular level factors on organ level function remain unclear. A computational model of the cardiovascular system that integrates cellular function into whole organ function has recently been developed. This model is a useful tool for investigating how changes in myocyte structure and mechanics contribute to organ function...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29995182/gastroesophageal-reflux-disease-might-induce-certain-supposedly-adaptive-changes-in-the-esophagus-a-hypothesis
#11
Laura Bognár, András Vereczkei, András Papp, Gábor Jancsó, Örs Péter Horváth
BACKGROUND: The increasing prevalence of GERD has become a major concern due to its major health and economic impacts. Beyond the typical unpleasant symptoms, reflux can also be the source of severe, potentially life-threatening complications, such as aspiration. AIM: Our aim was to support our hypothesis that the human body may in some cases develop various protective mechanisms to prevent these conditions. METHODS: Based on our experiences and review of the literature, we investigated the potential adaptive nature of seven reflux complications (hypertensive lower esophageal sphincter, achalasia, hypertensive upper esophageal sphincter, Zenker's diverticulum, Schatzki's ring, esophageal web, and Barrett's esophagus)...
July 11, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29991070/outcome-of-neonates-with-vein-of-galen-malformation-presenting-with-severe-heart-failure-a-case-series
#12
Gabriella De Rosa, Maria Pia De Carolis, Alessia Tempera, Alessandro Pedicelli, Massimo Rollo, Tony Christian Morena, Ersilia Luca, Daniele De Luca, Giorgio Conti, Marco Piastra
BACKGROUND:  Neonatal presentation of vein of Galen aneurysmal malformations (VGAMs) complicated by cardiac failure and pulmonary hypertension is frequently associated with a poor prognosis. Interventional neuroradiology with embolization can offer a chance for survival, although neurological damage can represent a limitation. OBJECTIVE:  This article determines if aggressive intensive care and drug management of cardiac failure before urgent embolization can influence morbidity and mortality...
July 10, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29990607/dynamic-changes-in-tlr4-in-human-perihematoma-tissue-after-intracerebral-hemorrhage
#13
Xiaokun Gang, Qing Han, Xue Zhao, Qun Liu, Yao Wang
BACKGROUND: With the increase in the aging population and unhealthy lifestyles, the prevalence of intracerebral hemorrhage (ICH) continues to rise. The secondary injury to brain tissue after ICH might play a significant role in the prognosis of the patient; however, the underlying mechanisms of this process are unclear. This study aimed to explore the function of the Toll-like receptor 4 (TLR4)-mediated myeloid differentiation primary response 88 (MyD88)-dependent pathway in inflammatory injury and apoptosis in the perihematoma tissues of patients with ICH...
July 7, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29985201/association-of-systolic-blood-pressure-with-cardiovascular-outcomes-in-elderly-patients-with-hypertension-in-northern-china
#14
Xiaobin Guo, Yesong Liu, Nan Yang, Ping Liu, Ying Zhu, Xiaoshuang Xia, Wenxia Yu, Chumin Zhao, Lin Wang, Shouling Wu, Xin Li
OBJECTIVE: The aim of this study was to investigate the association of systolic blood pressure (SBP) with cardiovascular disease and all-cause mortality among elderly hypertensive patients in northern China. PARTICIPANTS AND METHODS: In this prospective cohort study, 9655 elderly hypertensive patients from Kailuan study were followed up with the incidence of primary outcomes (composite outcomes including myocardial infarction, stroke, and all-cause death) and the incidence of secondary outcomes (stroke, myocardial infarction, and all-cause death)...
July 5, 2018: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29984004/a-rare-case-of-complete-heart-block-in-a-young-patient
#15
Zakaria Hindi, Yousef Hindi, Rami Batarseh
Introduction: Complete heart block (CHB) is considered as one of the dangerous rhythms since it can progress to lethal arrhythmias such as ventricular tachycardia. It can be congenital or acquired. Patients may present with frequent palpitations, presyncope, dyspnea, or chest pain but also may remain asymptomatic. Extensive work-up should be conducted to exclude secondary causes such as infections, cardiac ischemia or myopathies, autoimmune diseases, or endocrinological diseases. In our paper, we would like to present a case of CHB in the setting of aortic abdominal thrombus that nearly occluded both renal arteries...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29983820/effect-of-exposure-to-cement-dust-among-the-workers-an-evaluation-of-health-related-complications
#16
Arshad H Rahmani, Ahmad Almatroudi, Ali Yousif Babiker, Amjad A Khan, Mohammed A Alsahly
BACKGROUND: Cement contains various types of chemicals in addition to lime and silica, and such chemicals cause different health complications and pathogenesis in addition to respiratory disorders. The most important occupational hazards for cement workers are allergy and complication related to respiratory system. AIM: The current study was performed by analysing the questionnaire distributed among the workers and also by the sputum collected from them to study the general health conditions and other life activities...
June 20, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29983819/trend-and-causes-of-maternal-mortality-in-a-nigerian-tertiary-hospital-a-5-year-retrospective-study-2010-2014-at-the-university-of-calabar-teaching-hospital-calabar-nigeria
#17
Thomas U Agan, Emmanuel Monjok, Ubong B Akpan, Ogban E Omoronyia, John E Ekabua
BACKGROUND: Maternal mortality ratios (MMR) are still unacceptably high in many low-income countries especially in sub-Saharan Africa. MMR had been reported to have improved from an initial 3,026 per 100,000 live births in 1999 to 941 in 2009, at the University of Calabar Teaching Hospital (UCTH), Calabar, a tertiary health facility in Nigeria. Post-partum haemorrhage and hypertensive diseases of pregnancy have been the common causes of maternal deaths in the facility. AIM: This study was aimed at determining the trend in maternal mortality in the same facility, following institution of some facility-based intervention measures...
June 20, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29982610/vegetarian-diets-and-chronic-kidney-disease
#18
Philippe Chauveau, Laetitia Koppe, Christian Combe, Catherine Lasseur, Stanislas Trolonge, Michel Aparicio
While dietary restriction of protein intake has long been proposed as a possible kidney-protective treatment, the effects of changes in the quality of ingested proteins on the prevalence and risk of progression of chronic kidney disease (CKD) have been scarcely studied; these two aspects are reviewed in the present article. The prevalence of hypertension, type 2 diabetes and metabolic syndrome, which are the main causes of CKD in Western countries, is lower in vegetarian populations. Moreover, there is a negative relationship between several components of plant-based diets and numerous factors related to CKD progression such as uraemic toxins, inflammation, oxidative stress, metabolic acidosis, phosphate load and insulin resistance...
July 5, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29982477/severe-maternal-morbidity-in-women-with-high-bmi-in-ivf-and-unassisted-singleton-pregnancies
#19
N Dayan, D B Fell, Y Guo, H Wang, M P Velez, K Spitzer, C A Laskin
STUDY QUESTION: Is there a synergistic risk of severe maternal morbidity (SMM) in overweight/obese women who conceived by IVF compared to normal-weight women without IVF? SUMMARY ANSWER: SMM was more common in IVF pregnancies, and among overweight/obese women, but we did not detect a synergistic effect of both factors. WHAT IS KNOWN ALREADY: While much is known about the impact of overweight and obesity on success rates after IVF, there is less data on maternal health outcomes...
July 3, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29982243/cerebrovascular-accident-risk-in-a-population-with-periodic-limb-movements-of-sleep-a-preliminary-meta-analysis
#20
REVIEW
Tzu-Chao Lin, Bing-Yan Zeng, Yen-Wen Chen, Meng-Ni Wu, Tien-Yu Chen, Pao-Yen Lin, Ching-Kuan Wu, Ping-Tao Tseng, Chung-Yao Hsu
BACKGROUND AND PURPOSE: Periodic limb movements of sleep (PLMS) are usually comorbid with hypertension, tachycardia, and coronary arterial diseases, which are also risk factors for cerebrovascular accidents (CVA). However, evidence about the relationship between CVA and PLMS is still weak. The aim of this study was to investigate (1) the prevalence of CVA in patients with PLMS, and (2) the severity of PLMS in patients with or without CVA through a meta-analysis. METHODS: The electronic databases of PubMed, Embase, ScienceDirect, ClinicalKey, Cochrane Library, ProQuest, Web of Science, and ClinicalTrials...
July 6, 2018: Cerebrovascular Diseases
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