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https://www.readbyqxmd.com/read/28421908/extravasating-uterine-pseudoaneurysm-a-rare-cause-of-postpartum-haemorrhage
#1
Sang Wook Yi
Postpartum haemorrhage (PPH) remains one of the leading causes of maternal death worldwide and can be classified as either immediate (primary) or delayed (secondary) according to the onset time - before or after 24 hours postpartum. Uterine pseudoaneurysm is a rare cause of PPH that has been suggested to arise from abnormal vascular regression and a recurrent vascular healing state, such as a vascular stricture and relaxation with thrombin deposits after placental expulsion. With advances in multidetector computed tomography, 3D-computed tomography with angiography can aid in identifying the location and originating vessels of the pseudoaneurysm via fast and clear 3D images...
May 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28420498/intraoperative-aortic-balloon-occlusion-in-patients-with-placenta-previa-and-or-placenta-accreta-a-retrospective-study
#2
Fangyuan Luo, Lan Xie, Ping Xie, Siwei Liu, Yue Zhu
OBJECTIVE: To introduce the primary experience of using aortic balloon catheters during cesarean section for placenta previa and/or placenta accreta. MATERIALS AND METHODS: From January 2013 to May 2015, 43 patients who were preoperatively diagnosed with major placenta previa and/or placenta accreta and who underwent prophylactic aortic catheterization before caesarean section (CS) were included in the study. We analyzed the clinical data of the study population...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28420496/the-value-of-hysteroscopic-management-of-cesarean-scar-pregnancy-a-report-of-44-cases
#3
Ying Pan, Mu-Biao Liu
OBJECTIVE: With the incidence of cesarean scar pregnancy (CSP) rising, the reports of serious adverse outcomes of it have increased gradually. The management of CSP remains an inadequately explored clinical field, and there is no consensus on it presently. The present study was performed to investigate the efficacy and safety of operative hysteroscopy in the diagnosis and treatment of CSP. MATERIALS AND METHODS: Forty-four patients with CSP underwent operative hysteroscopy for removal of scar ectopic pregnancy in our institution...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28416375/automatic-and-manual-doppler-velocimetry-measurements-of-the-uterine-artery-in-pregnant-ewes
#4
Renato Travassos Beltrame, Lucas Buss Littig, Carolina Covre, Amanda de Barros Martins, Celia Raquel Quirino, R L D Costa
We aimed to compare measurements of speed and blood flow parameters obtained manually and automatically in the uterine arteries of pregnant ewes. Eighteen Santa Inês ewes, confirmed to be pregnant, were followed every 2 weeks until parturition. The systolic peak (PS), end diastolic velocity (ED), maximum and average speed in the cardiac cycle (TAMAX and TAMEAN, respectively), pulsatility index (PI), resistance index (RI) and the systole/diastole (S/D) ratio and body flow volume (BFV) was measured. We began the wave evaluation automatically, then the observer manually marked the beginning and end of the wave...
March 31, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28412995/development-and-validation-of-prediction-models-for-risks-of-complications-in-early-onset-pre-eclampsia-prep-a-prospective-cohort-study
#5
Shakila Thangaratinam, John Allotey, Nadine Marlin, Ben W Mol, Peter Von Dadelszen, Wessel Ganzevoort, Joost Akkermans, Asif Ahmed, Jane Daniels, Jon Deeks, Khaled Ismail, Ann Marie Barnard, Julie Dodds, Sally Kerry, Carl Moons, Richard D Riley, Khalid S Khan
BACKGROUND: The prognosis of early-onset pre-eclampsia (before 34 weeks' gestation) is variable. Accurate prediction of complications is required to plan appropriate management in high-risk women. OBJECTIVE: To develop and validate prediction models for outcomes in early-onset pre-eclampsia. DESIGN: Prospective cohort for model development, with validation in two external data sets. SETTING: Model development: 53 obstetric units in the UK...
April 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28412461/effects-of-low-dose-aspirin-on-maternal-blood-pressure-and-vascular-function-in-an-experimental-model-of-gestational-hypertension
#6
Oluwatobiloba Osikoya, Paresh A Jaini, An Nguyen, Melissa Valdes, Styliani Goulopoulou
Daily intake of low-dose aspirin after 12weeks of gestation is currently recommended as a preventative intervention in pregnancies in high risk of developing preeclampsia. This recommendation is based on epidemiological evidence, whereas experimental studies investigating the exact mechanisms of aspirin action during pregnancy are lacking. We previously showed that treating pregnant rats with a synthetic mimetic of unmethylated CpG DNA (bacterial DNA) caused preeclampsia-like characteristics such as maternal hypertension and increased cyclooxygenase (COX) expression and activity...
April 12, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28410263/volatile-sedation-in-reversible-cerebral-vasoconstriction-syndrome-a-case-report
#7
Michael Ramming, Joachim Bansbach, Christopher Beck, Johannes Kalbhenn
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by reversible multifocal narrowing of cerebral arteries heralded by sudden (thunderclap) headaches with or without neurological deficits, resolving within 3 months. It often occurs in the peripartum period. To date, the ideal treatment remains unclear.Here, we report the case of a 31-year-old primigravida who presented with intracranial hemorrhage and went on to develop RCVS and acute respiratory distress syndrome over the course of her illness...
April 13, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28409499/use-of-placental-vascularization-indices-and-uterine-artery-peak-systolic-velocity-in-early-detection-of-pregnancies-complicated-by-gestational-diabetes-chronic-or-gestational-hypertension-and-preeclampsia-at-risk
#8
Ábel T Altorjay, Andrea Surányi, Tibor Nyári, Gábor Németh
AIM: We aimed to investigate correlations between uterine artery peak systolic velocity (AUtPSV), and placental vascularization in groups of normal blood pressure (NBP) and hypertensive disorders of pregnancy (chronic hypertension (CHT), gestational hypertension (GHT) and preeclampsia (PE)) alone or in combination with gestational diabetes mellitus (GDM), and hypothesized that AUtPSV rises when GDM complicates pregnancy hypertension. METHODS: Placental 3-dimensional power Doppler indices, such as vascularization index (VI), flow index (FI), and vascularization-flow index (VFI), and uterine artery peak systolic velocity (AUtPSV) were measured in CHT (N=43), CHT+GDM (N=15), GHT (N=57), GHT+GDM (N=23) and PE (N=17) pregnancies, and compared to NBP (N=109)...
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28406930/eutopic-ectopic-endometrial-apoptosis-initiated-by-bilateral-uterine-artery-occlusion-a-new-therapeutic-mechanism-for-uterus-sparing-surgery-in-adenomyosis
#9
Li Chen, Caixia Li, Jing Guo, Ning Luo, Xiaoyan Qu, Le Kang, Mingmin Liu, Zhongping Cheng
The objective of the present study was to investigate differences in the expression of apoptosis-related factors in the eutopic and ectopic endometrium (EuE/EE) in women with adenomyosis before and after laparoscopic bilateral uterine artery occlusion (LUAO). Ten patients with uterine adenomyosis who received LUAO were selected as the research subjects, from whom EuE and EE tissues were obtained before and after LUAO and detected for the expression of apoptosis-related molecules in EuE and EE by PT-PCR and Western blot, and changes in the mitochondrial structure by electron microscopy...
2017: PloS One
https://www.readbyqxmd.com/read/28403929/-conservative-placenta-percreta-management-using-uterine-arterial-embolization-procedure-a-series-of-12-cases
#10
C Hennetier, M Daudruy Brasseur, S Patrier, E Clavier, M L Thibault, E Verspyck
We report a retrospective series of 12 placentas percreta with bladder invasion and for which an expected initially multidisciplinary conservative surgical treatment associated with uterine artery embolization was programmed. Conservative surgical treatment was only performed in 7 women. Radical surgical treatment was necessary during the caesarean section and complicated by massive hemorrhage in three women and secondary in two other women for infectious diseases. Radical surgical treatment was associated with partial cystectomy complicated with urinary disorder sequelae in three women...
March 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28398541/pregnancy-augments-vegf-stimulated-in-vitro-angiogenesis-and-vasodilator-no-and-h2s-production-in-human-uterine-artery-endothelial-cells
#11
Hong-Hai Zhang, Jennifer C Chen, Lili Sheibani, Thomas J Lechuga, Dong-Bao Chen
Context: Augmented uterine artery (UA) production of vasodilators including nitric oxide (NO) and hydrogen sulfide (H2S) has been implicated in pregnancy-associated and agonist-stimulated rise in uterine blood flow that is rate-limiting to pregnancy health. Objective: Developing a human UA endothelial cell (hUAEC) culture model from main UAs of nonpregnant (NP) and pregnant (P) women for testing a hypothesis that pregnancy augments endothelial NO and H2S production and endothelial reactivity to vascular endothelial growth factor (VEGF)...
April 7, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28397667/-uterine-artery-pseudoaneurysm-is-a-rare-delayed-complication-after-caesarean-section
#12
Julie Lyngsø, Janne Kainsbak, Marianne Østergård
Uterine artery pseudoaneurysm is a rare complication after caesarean section and may be the cause of acute and potentially life-threatening secondary post-partum haemorrhage. In this case report, we present the clinical presentation and management of a case of uterine artery pseudoaneurysm manifesting as delayed post-partum bleeding after caesarean section. The case report emphasizes the importance of performing Doppler-flow when diagnosing the existence of a uterine artery pseudoaneurysm ultrasonically.
January 30, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28397200/impact-of-pelvic-magnetic-resonance-imaging-findings-in-the-indication-of-uterine-artery-embolization-in-the-treatment-of-myoma
#13
Norma Maria Tenório Brito Pires, Emmanuelle Tenório Godoi, Dinaldo Cavalcanti Oliveira, Simone Cristina Soares Brandão, Carlos Coutinho Abath, Pedro Pires, Edward Araujo Júnior
OBJECTIVES: To assess the impact of pelvic magnetic resonance imaging (MRI) findings in the indication for uterine-artery embolization in women with fibroids, as well as the correlation between MRI and ultrasound (US) examinations for diagnosing adenomyosis. MATERIAL AND METHODS: A retrospective observational study was performed through the analysis of the medical records of 263 women referred for uterine-artery embolization as treatment for fibroids after undergoing US and MRI examinations...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28396535/pregnancy-reprograms-large-conductance-ca-2-activated-k-channel-in-uterine-arteries-roles-of-ten-eleven-translocation-methylcytosine-dioxygenase-1-mediated-active-demethylation
#14
Xiang-Qun Hu, Chiranjib Dasgupta, Man Chen, Daliao Xiao, Xiaohui Huang, Limin Han, Shumei Yang, Zhice Xu, Lubo Zhang
The large-conductance Ca(2+)-activated K(+) (BKCa) channel is of critical importance in pregnancy-mediated increase in uterine artery vasodilation and blood flow. The present study tested the hypothesis that active DNA demethylation plays a key role in pregnancy-induced reprogramming and upregulation of BKCa channel β1 subunit (BKβ1) in uterine arteries. Uterine arteries were isolated from nonpregnant and near-term pregnant sheep. Pregnancy significantly increased the expression of ten-eleven translocation methylcytosine dioxygenase 1 (TET1) in uterine arteries...
April 10, 2017: Hypertension
https://www.readbyqxmd.com/read/28396005/transradial-access-for-interventional-radiology-single-centre-procedural%C3%A2-and-clinical-outcome-analysis
#15
Avnesh S Thakor, Mohammed T Alshammari, David M Liu, John Chung, Stephen G F Ho, Gerald M Legiehn, Lindsay Machan, Aaron M Fischman, Rahul S Patel, Darren Klass
PURPOSE: The study sought to describe a single centre's technical approach to transradial intervention and report on clinical outcomes and safety. METHODS: A total of 749 transradial access (TRA) procedures were performed at a single hospital in 562 patients (174 women and 388 men). Procedures included 445 bland embolizations or chemoembolizations of the liver, 88 uterine artery embolizations, and 148 procedures for Selective Internal Radiation Therapy (Y90), which included mapping and administration...
April 7, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28395415/-clinical-features-and-outcome-of-cesarean-scar-pregnancy
#16
Y J Wang, Y Zhai, Z Y Zhang
Objective: To analysis the clinical features of cesarean scar pregnancy (CSP), to evaluate the therapeutic effect of various treatments, especially the feasibility and advantage of Methotrexate (MTX)-Uterine artery embolization (UAE)- Sonogrphy directed-In situs aspiration sequential therapy based on the pregnancy sac three-dimensional conformation analysis (3D-MESIA). Methods: From January 2007 to December 2014, 99 subjects who were diagnosed as CSP in Chaoyang Hospital of Capital Medical University were studied retrospectively...
April 4, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28395334/natural-killer-cell-deficiency-alters-placental-development-in-rats
#17
Stephen J Renaud, Regan L Scott, Damayanti Chakraborty, Mohammad A K Rumi, Michael J Soares
Natural killer (NK) cells are the most prevalent leukocyte population in the uterus during early pregnancy. Natural killer cells contribute to uterine vascular (spiral artery) remodeling in preparation for the increased demand on these vessels later in pregnancy. A second wave of spiral artery modification is directed by invasive trophoblast cells. The significance of the initial wave of NK-cell-mediated vascular remodeling in species exhibiting deep trophoblast invasion such as humans and rats is not known...
January 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28395328/cystic-endometrial-hyperplasia-pyometra-syndrome-in-bitches-identification-of-hemodynamic-inflammatory-and-cell-proliferation-changes%C3%A2
#18
Gisele Almeida Lima Veiga, Ricardo Henrique Miziara, Daniel Souza Ramos Angrimani, Paula Carvalho Papa, Bruno Cogliati, Camila Infantosi Vannucchi
Cystic endometrial hyperplasia (CEH)-pyometra syndrome is one of the most common diseases of noncastrated female dogs. However, determination of etiological mechanisms and differential diagnosis of CEH-pyometra syndrome are undefined. The aim of this study is to compare immunohistochemically the expression of cyclooxygenase-2 (COX-2) inflammatory mediator, Ki-67 antigen proliferation marker, vascular endothelial growth factor (VEGF-A) angiogenesis mediator and its FLT-1 and KDR receptors, and correlate with Doppler velocimetry of uterine artery and endometrial vascularization in bitches with CEH-pyometra syndrome...
January 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28376314/endogenous-lysophosphatidic-acid-participates-in-vascularisation-and-decidualisation-at-the-maternal-fetal-interface-in-the-rat
#19
Micaela S Sordelli, Jimena S Beltrame, Elsa Zotta, Natalia Gomez, Ganna Dmytrenko, María Elena Sales, Sandra M Blois, Carlos Davio, Silvina Perez Martinez, Ana M Franchi, María L Ribeiro
Lysophosphatidic acid (LPA) affects several female reproductive functions through G-protein-coupled receptors. LPA contributes to embryo implantation via the lysophospholipid LPA3 receptor. In the present study we investigated the participation of endogenous LPA signalling through the LPA3 receptor in vascularisation and decidualisation, two crucial events at the maternal-fetal interface. Pregnant rats were treated with diacylglycerol pyrophosphate (DGPP), a highly selective antagonist of LPA3 receptors, on Day 5 of gestation...
April 5, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28374437/re-impact-of-aspirin-on-trophoblastic-invasion-in-women-with-abnormal-uterine-artery-doppler-at-11-14-weeks-a-randomized-controlled-study-e-scazzocchio-d-oros-d-diaz-j-c-ramirez-m-ricart-e-meler-r-gonz%C3%A3-lez-de-ag%C3%A3-ero-e-gratacos-and-f-figueras-ultrasound-obstet
#20
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