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Neurorehabilitation

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https://www.readbyqxmd.com/read/29145345/the-role-of-sativex-in-robotic-rehabilitation-in-individuals-with-multiple-sclerosis-rationale-study-design-and-methodology
#1
Margherita Russo, Vincenzo Dattola, Anna Lisa Logiudice, Rosella Ciurleo, Edoardo Sessa, Rosaria De Luca, Placido Bramanti, Alessia Bramanti, Antonino Naro, Rocco Salvatore Calabrò
INTRODUCTION: Currently, none of the available multiple sclerosis (MS) disease-modifying medications has been shown to stop or reverse gait disability. Recently, the nabiximols has been tested for the treatment of spasticity and walking impairment in MS. Nabiximols (trade name Sativex) is an oromucosal spray formulation containing 1:1 fixed ratio of delta-9-tetrahydrocannabinol and cannabidiol derived from cloned Cannabis sativa L. plant. METHOD AND ANALYSIS: A single-center, prospective, parallel design, single-blind trial will be conducted at the IRCCS Neurolesi "Bonino-Pulejo" (Italy) involving MS patients affected by spasticity and undergoing a Robotic Rehabilitation training...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29130382/less-affected-hand-function-in-children-with-hemiparetic-unilateral-cerebral-palsy-a-comparison-study-with-typically-developing-peers
#2
Tonya L Rich, Jeremiah S Menk, Kyle D Rudser, Timothy Feyma, Bernadette T Gillick
BACKGROUND: Neurorehabilitation interventions in children with unilateral cerebral palsy (UCP) target motor abilities in daily life yet deficits in hand skills persist. Limitations in the less-affected hand may affect overall bimanual hand skills. OBJECTIVE: To compare hand function, by timed motor performance on the Jebsen-Taylor Test of Hand Function (JTTHF) and grip strength of children with UCP to children with typical development (CTD), aged 8 to 18 years old...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29123403/effects-of-short-term-piano-training-on-measures-of-finger-tapping-somatosensory-perception-and-motor-related-brain-activity-in-patients-with-cerebral-palsy
#3
Ana Alves-Pinto, Stefan Ehrlich, Gordon Cheng, Varvara Turova, Tobias Blumenstein, Renée Lampe
Playing a musical instrument demands the integration of sensory and perceptual information with motor processes in order to produce a harmonic musical piece. The diversity of brain mechanisms involved and the joyful character of playing an instrument make musical instrument training a potential vehicle for neurorehabilitation of motor skills in patients with cerebral palsy (CP). This clinical condition is characterized by motor impairments that can affect, among others, manual function, and limit severely the execution of basic daily activities...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29120935/neuropathic-pain-experiences-of-spinal-cord-injury-patients
#4
Chin-Ching Li, Hung-Ru Lin, Ming-Dar Tsai, Shiow-Luan Tsay
BACKGROUND: Neuropathic pain (NP) is a common, severe problem that affects spinal cord injury (SCI) patients. Only SCI patients truly understand the impact and extent of this type of pain. PURPOSE: The aim of this study was to understand the NP experienced by SCI patients and the influence of this type of pain on their daily life. METHOD: A qualitative design was used. An interview guide including a semistructured questionnaire and in-depth interviews was conducted with SCI patients with NP in a neurorehabilitation department at a medical center in northern Taiwan...
November 9, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29115915/neuromodulation-in-multiple-sclerosis
#5
Hesham Abboud, Eddie Hill, Junaid Siddiqui, Alessandro Serra, Benjamin Walter
Neuromodulation, or the utilization of advanced technology for targeted electrical or chemical neuronal stimulation or inhibition, has been expanding in several neurological subspecialties. In the past decades, immune-modulating therapy has been the main focus of multiple sclerosis (MS) research with little attention to neuromodulation. However, with the recent advances in disease-modifying therapies, it is time to shift the focus of MS research to neuromodulation and restoration of function as with other neurological subspecialties...
November 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29115485/effect-of-willed-movement-training-on-neurorehabilitation-after-focal-cerebral-ischemia-and-on-the-neural-plasticity-associated-signaling-pathway
#6
Zhi-Wen Zhou, Qi-Dong Yang, Qing-Ping Tang, Jie Yang, Rong-Jing Guo, Wen Jiang
Neurorehabilitation training is a therapeutic intervention for the loss of neural function induced by focal cerebral ischemia, however, the effect varies depending on the neurorehabilitation exercises. Willed movement (WM) training is defined as task‑oriented training, which increases enthusiasm of patients to accomplish a specific task. The current study was performed to the evaluate effect of WM training on neurorehabilitation following focal cerebral ischemia, and further investigate the influence on neural plasticity‑associated signaling pathway...
November 3, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29114923/histamine-modulates-spinal-motoneurons-and-locomotor-circuits
#7
Tamara Coslovich, Michele R Brumley, Giuseppe D'Angelo, Alberto Della Mora, Hillary E Swann, Fulvia Ortolani, Giuliano Taccola
Spinal motoneurons and locomotor networks are regulated by monoamines, among which, the contribution of histamine has yet to be fully addressed. The present study investigates histaminergic regulation of spinal activity, combining intra- and extracellular electrophysiological recordings from neonatal rat spinal cord in vitro preparations. Histamine dose-dependently and reversibly generated motoneuron depolarization and action potential firing. Histamine (20 µM) halved the area of dorsal root reflexes and always depolarized motoneurons...
November 8, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29105605/the-feasibility-of-an-acute-high-intensity-exercise-bout-to-promote-locomotor-learning-after-stroke
#8
Charalambos C Charalambous, Erin E Helm, Kristin A Lau, Susanne M Morton, Darcy S Reisman
BACKGROUND: People post-stroke can learn a novel locomotor task but require more practice to do so. Implementing an approach that can enhance locomotor learning may therefore improve post-stroke locomotor recovery. In healthy adults, an acute high-intensity exercise bout before or after a motor task may improve motor learning and has thus been suggested as a method that could be used to improve motor learning in neurorehabilitation. However, it is unclear whether an acute high-intensity exercise bout, which stroke survivors can feasibly complete in neurorehabilitation session, would generate comparable results...
November 5, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29102670/and-yet-it-moves-recovery-of-volitional-control-after-spinal-cord-injury
#9
REVIEW
G Taccola, D Sayenko, P Gad, Y Gerasimenko, V R Edgerton
Preclinical and clinical neurophysiological and neurorehabilitation research has generated rather surprising levels of recovery of volitional sensory-motor function in persons with chronic motor paralysis following a spinal cord injury. The key factor in this recovery is largely activity-dependent plasticity of spinal and supraspinal networks. This key factor can be triggered by neuromodulation of these networks with electrical and pharmacological interventions. This review addresses some of the systems-level physiological mechanisms that might explain the effects of electrical modulation and how repetitive training facilitates the recovery of volitional motor control...
November 2, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/29072042/active-exergames-to-improve-cognitive-functioning-in-neurological-disabilities-a-systematic-review-and-meta-analysis
#10
Gioia Mura, Mauro G Carta, Federica Sancassiani, Sergio Machado, Luca Prosperini
INTRODUCTION: Exergames represent a way to perform physical activity through active video games, serving as potentially useful tool in the field of neurorehabilitation. However, little is known regarding the possible role of exergames in improving cognitive functions in persons suffering from neurological disabilities. EVIDENCE ACQUISITION: A search for relevant articles was carried out on PubMed/Medline, Scopus, PEDro, and Google Scholar. Only randomized controlled studies and non-randomized but controlled studies were retained...
October 25, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29064733/a-novel-tool-for-naturalistic-assessment-of-behavioural-dysregulation-after-traumatic-brain-injury-a-pilot-study
#11
Ashlee McKeon, Lauren Terhorst, Elizabeth Skidmore, Dan Ding, Rory Cooper, Michael McCue
OBJECTIVE: This study aimed to develop a novel tool for measuring behavioural dysregulation in adults with traumatic brain injury (TBI) using objective data sources and real-world application and provide preliminary evidence for its psychometric properties. RESEARCH DESIGN: Fourteen adults with TBI receiving services at a local brain injury rehabilitation programme completed multiple assessments of behaviour and followed by a series of challenging problem-solving tasks while being video recorded...
October 24, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29060078/motor-imagery-enhancement-paradigm-using-moving-rubber-hand-illusion-system
#12
Minsu Song, Jonghyun Kim
Motor imagery (MI) has been widely used in neurorehabilitation and brain computer interface. The size of event-related desynchronization (ERD) is a key parameter for successful motor imaginary rehabilitation and BCI adaptation. Many studies have used visual guidance for enhancement/ amplification of motor imagery ERD amplitude, but their enhancements were not significant. We propose a novel ERD enhancing paradigm using body-ownership illusion, or also known as rubber hand illusion (RHI). The system was made by motorized, moving rubber hand which can simulate wrist extension...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29058553/effects-of-body-weight-support-treadmill-training-on-postural-sway-and-gait-independence-in-patients-with-chronic-spinal-cord-injury
#13
Felipe Covarrubias-Escudero, Gonzalo Rivera-Lillo, Rodrigo Torres-Castro, Gonzalo Varas-Díaz
OBJECTIVE: To examine the effects of a six-week body weight-support treadmill training (BWSTT) program on center-of-mass control and gait independence in chronic, incomplete spinal cord injury (iSCI) patients. DESIGN: Descriptive. SETTING: Clinica Los Coihues. Neurorehabilitation center in Santiago, Chile. PARTICIPANTS: 17 chronic iSCI patients and 17 healthy subjects. OUTCOME MEASURES: An instrumented sway (ISway) test was performed before and after the implementation of a six-week BWSTT program...
October 23, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29055718/online-detection-of-amplitude-modulation-of-motor-related-eeg-desynchronization-using-a-lock-in-amplifier-comparison-with-a-fast-fourier-transform-a-continuous-wavelet-transform-and-an-autoregressive-algorithm
#14
Kenji Kato, Kensho Takahashi, Nobuaki Mizuguchi, Junichi Ushiba
BACKGROUND: Neurofeedback of event-related desynchronization (ERD) in electroencephalograms (EEG) of the sensorimotor cortex (SM1) using a brain-computer interface (BCI) paradigm is a powerful tool to promote motor recovery from post-stroke hemiplegia. However, the feedback delay attenuates the degree of motor learning and neural plasticity. NEW METHOD: The present study aimed to shorten the delay time to estimate amplitude modulation of the motor-imagery-related alpha and beta SM1-ERD using a lock-in amplifier (LIA) algorithm...
October 20, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29036840/efficacy-of-memory-aids-after-traumatic-brain-injury-a-single-case-series
#15
Hannah R Bos, Duncan R Babbage, Janet M Leathem
BACKGROUND: Individuals living with traumatic brain injury commonly have difficulties with prospective memory-the ability to remember a planned action at the intended time. Traditionally a memory notebook has been recommended as a compensatory memory aid. Electronic devices have the advantage of providing a cue at the appropriate time to remind participants to refer to the memory aid and complete tasks. Research suggests these have potential benefit in neurorehabilitation. OBJECTIVE: This study aimed to investigate the efficacy of a memory notebook and specifically a smartphone as a compensatory memory aid...
2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/29036838/neurosexuality-a-transdisciplinary-approach-to-sexuality-in-neurorehabilitation
#16
Alexander Moreno, Caron Gan, Nathan D Zasler
No abstract text is available yet for this article.
2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/29020968/robot-assisted-assessment-of-muscle-strength
#17
REVIEW
Marco Toigo, Martin Flück, Robert Riener, Verena Klamroth-Marganska
Impairment of neuromuscular function in neurological disorders leads to reductions in muscle force, which may lower quality of life. Rehabilitation robots that are equipped with sensors are able to quantify the extent of muscle force impairment and to monitor a patient during the process of neurorehabilitation with sensitive and objective assessment methods. In this article, we provide an overview of fundamental aspects of muscle function and how the corresponding variables can be quantified by means of meaningful robotic assessments that are primarily oriented towards upper limb neurorehabilitation...
October 11, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29020472/effect-of-transcranial-direct-current-stimulation-combined-with-cognitive-training-on-cognitive-functioning-in-older-adults-with-hiv-a-pilot-study
#18
Pariya L Fazeli, Adam J Woods, Caitlin N Pope, David E Vance, Karlene K Ball
The objective of this study was to examine combination speed of processing (SOP) cognitive remediation therapy (CRT) and transcranial direct stimulation (tDCS) as neurorehabilitation in older HIV+ adults. Thirty-three HIV+ adults aged 50+ completed neurocognitive testing and were randomized to either active (n = 17) or sham (n = 16) tDCS. Both conditions received 10 1-hour sessions of SOP CRT, with either active or sham tDCS for the first 20 minutes. Participants then completed a posttest assessment...
October 11, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/29018503/parameters-influencing-tracheostomy-decannulation-in-patients-undergoing-rehabilitation-after-severe-acquired-brain-injury-sabi
#19
Cecilia Perin, Roberto Meroni, Vincenzo Rega, Giacomo Braghetto, Cesare Giuseppe Cerri
Introduction  Tracheostomy weaning in patients who suffered a severe acquired brain injury is often a challenge and decannulation failures are not uncommon. Objective  Our study objective is to describe the decannulation failure rate in patients undergoing rehabilitation following a severe acquired brain injury (sABI); to describe the factors associated with a successful tube weaning. Methods  We conduct a retrospective analysis of charts, consecutively retrieved considering a 3-year window. Variables analyzed were: age, sex, body mass index (BMI), Glasgow Coma Scale (GCS), cause of hospitalization (stroke, trauma, cardiac arrest), date of the pathological event, gap between the index event and the first day of hospitalization, duration of Neurorehabilitation Ward hospitalization, comorbidities, chest morphological alteration, kind of tracheostomy tube used (overall dimension, cap, fenestration), SpO2, presentation and quantification of pulmonary secretion, maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP), respiratory frequency and pattern, cardiac frequency, presence of spontaneous cough, cough strength, and blood gas analysis...
October 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28986411/virtual-reality-improves-embodiment-and-neuropathic-pain-caused-by-spinal-cord-injury
#20
RANDOMIZED CONTROLLED TRIAL
Polona Pozeg, Estelle Palluel, Roberta Ronchi, Marco Solcà, Abdul-Wahab Al-Khodairy, Xavier Jordan, Ammar Kassouha, Olaf Blanke
OBJECTIVE: To investigate changes in body ownership and chronic neuropathic pain in patients with spinal cord injury (SCI) using multisensory own body illusions and virtual reality (VR). METHODS: Twenty patients with SCI with paraplegia and 20 healthy control participants (HC) participated in 2 factorial, randomized, repeated-measures design studies. In the virtual leg illusion (VLI), we applied asynchronous or synchronous visuotactile stimulation to the participant's back (either immediately above the lesion level or at the shoulder) and to the virtual legs as seen on a VR head-mounted display...
October 31, 2017: Neurology
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