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Burn Injury

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https://www.readbyqxmd.com/read/29222629/postinflammatory-hyperpigmentation-epidemiology-clinical-presentation-pathogenesis-and-treatment
#1
REVIEW
Bridget P Kaufman, Taulun Aman, Andrew F Alexis
Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis that develops following cutaneous inflammation. Common causes of PIH include intrinsic skin conditions (e.g., acne and eczema) as well as external insults to the skin, such as burn injuries and dermatologic procedures. PIH more commonly occurs in individuals with darker skin, for whom it is often a source of significant psychological distress. Several therapeutic modalities are available for the treatment of PIH, including topical agents, chemical peels, and energy-based devices...
December 8, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/29222584/-preservation-of-the-outer-ear-in-a%C3%A2-complex-burn-injury
#2
Fabian Medved, Hans-Eberhard Schaller, Jens Martin Rothenberger, Manuel Held, Kevin Beutler, Cedric E Boesch
Saving the outer ear in burn injuries is a challenging task for the treating surgeon that should not be underestimated. Burns which are initially evaluated as superficial, particularly in this region, often have a tendency to undergo progressive tissue destruction whereby conservative treatment is often no longer sufficient to preserve the skin of the auricle with the underlying cartilage. Various possibilities for saving the ear and for ear reconstruction are described, but in the case of severely burned patients it is often necessary to carry out a quick and relatively simple treatment...
December 8, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29218280/the-effect-of-lithospermum-officinale-silver-sulfadiazine-and-alpha-ointments-in-healing-of-burn-wound-injuries-in-rat
#3
Zahra Mohtasham Amiri, Nader Tanideh, Anahita Seddighi, Maral Mokhtari, Masood Amini, Alborz Shakouri Partovi, Amir Manafi, Seyedeh Sara Hashemi, Davood Mehrabani
BACKGROUND: Burn is the most devastating condition in emergency medicine leading to chronic disabilities. This study aimed to compare the effect of Lithospermum officinale, silver sulfadiazine and alpha ointments on healing of burn wounds in rat. METHODS: Ninety-five rats were divided into 5 groups. Group 1 just underwent burn injury, and groups 2-5 received alpha ointment, silver sulfadiazine (SSD), gel base and L. officinale extract, respectively. A hot plate was used for induction of a standard 3rd degree burn wound...
September 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/29218277/effect-of-multimedia-self-care-education-on-quality-of-life-in-burn-patients
#4
Fatemeh Mohaddes Ardebili, Tahereh Najafi Ghezeljeh, Mehri Bozorgnejad, Mohammadreza Zarei, Hooman Ghorbani, Farzad Manafi
BACKGROUND: Burn injuries can have adverse effects on quality of life of patients and can disturb their physiological, psychological, social and spiritual well-being. This study aimed to investigate the effect of multimedia self-care program on quality of life in burn patients. METHODS: This Randomized controlled clinical trial was conducted from November 2015 to December 2016. The samples were hospitalized burn patients with 10% to 45% of 1st, 2nd and 3rd degree burns of total body surface area (TBSA)...
September 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/29215833/-effect-of-conditioned-medium-from-mesenchymal-stem-cells-on-regeneration-of-endothelium-at-hcl-induced-damage-trachea-in-rats
#5
A A Temnov, A G Volkova, A V Melerzanov, V I Novoselov
The purpose. Respiratory epithelium regeneration is studied in rats with tracheal damage induced by inhaling hydrochloric acid vapor. Method. Regeneration process after the chemical burn was activated by intratracheal administration of preparations obtained from the same-species mesenchymal stem cells (MSC). Results. Tracheal epithelium is shown to recover almost completely on day 3-7 after applying MSC compositions (MSCs). Closed structures containing ciliated cells similar to ciliated cells of the respiratory epithelium lining the trachea are formed in the submucosal epithelium during regeneration...
April 2017: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
https://www.readbyqxmd.com/read/29214853/psychometric-properties-of-the-satisfaction-with-life-scale-in-people-with-traumatic-brain-spinal-cord-or-burn-injury-a-national-institute-on-disability-independent-living-and-rehabilitation-research-model-system-study
#6
Dagmar Amtmann, Fraser D Bocell, Alyssa Bamer, Allen W Heinemann, Jeanne M Hoffman, Shannon B Juengst, Marta Rosenberg, Jeffery C Schneider, Shelley Wiechman, Kara McMullen
This study evaluated the measurement properties of the Satisfaction With Life Scale (SWLS) in a sample of 17,897 people with spinal cord injury (48%, n = 8,566), traumatic brain injury (44%, n = 7,941), and burn injury (8%, n = 1,390), 1 year following injury. We examined measurement invariance across the groups, unidimensionality, local independence, reliability from a classical test and item response theory (IRT) framework, and fit to a unidimensional IRT model. The results support unidimensionality and local independence of the SWLS...
February 1, 2017: Assessment
https://www.readbyqxmd.com/read/29209994/the-role-of-trypsin-chymotrypsin-in-tissue-repair
#7
REVIEW
Dilip Shah, Kushal Mital
Tissue damage of all types, such as surgical or accidental injuries, fractures, and burns, stimulates a well-orchestrated, physiological process of healing, which ultimately leads to structural and functional restoration of the damaged tissues. The tissue repair process can be broadly divided into four continuous and overlapping phases-hemostasis and coagulation, inflammation, proliferation, and remodeling. If the process is interrupted or halted during any stage, it leads to impaired healing and formation of a chronic wound...
December 5, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29207887/burn-care-and-rehabilitation-in-australia-health-professionals-perspectives
#8
Rachel Kornhaber, Greg Rickard, Loyola McLean, Rick Wiechula, Violeta Lopez, Michelle Cleary
OBJECTIVE: To understand health professionals' perspectives of burn care and rehabilitation. DESIGN: Qualitative and semi-structured interviews. SETTING: Australian burn and rehabilitation units. PARTICIPANTS: Twenty-two clinicians working in burns units across disciplines and healthcare settings. RESULTS: The data portrayed the health professionals' perspectives of burn care and rehabilitation in Australia...
December 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29207058/protective-effect-of-baicalin-against-severe-burn%C3%A2-induced-remote-acute-lung-injury-in-rats
#9
Chongfeng Bai, Tao Li, Qing Sun, Qun Xin, Tongyi Xu, Jinjian Yu, Yun Wang, Li Wei
Baicalin exhibits antibacterial, anti‑viral, anti‑oxidative, antipyretic, analgesic, anti‑inflammatory and anti‑tumor properties. The chemical scavenges oxygen free radicals, protects the cardiovascular system and neurons, protects the liver, and has been used for the prevention and treatment of diabetes‑associated complications. The present study investigated the effect of baicalin on severe burn‑induced remote acute lung injury (ALI). The present study demonstrated that baicalin significantly decreased the lung wet‑to‑dry weight ratio, improved pulmonary histological alterations and reduced the expression of high mobility group protein B1 in the rat model of ALI...
November 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29206739/the-quest-to-preserve-muscle-mass-lessons-from-pediatric-burn-injury
#10
Nilesh M Mehta
No abstract text is available yet for this article.
December 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29203713/therapeutic-potential-of-heat-shock-protein-induction-for-muscular-dystrophy-and-other-muscle-wasting-conditions
#11
REVIEW
Savant S Thakur, Kristy Swiderski, James G Ryall, Gordon S Lynch
Duchenne muscular dystrophy is the most common and severe of the muscular dystrophies, a group of inherited myopathies caused by different genetic mutations leading to aberrant expression or complete absence of cytoskeletal proteins. Dystrophic muscles are prone to injury, and regenerate poorly after damage. Remorseless cycles of muscle fibre breakdown and incomplete repair lead to progressive and severe muscle wasting, weakness and premature death. Many other conditions are similarly characterized by muscle wasting, including sarcopenia, cancer cachexia, sepsis, denervation, burns, and chronic obstructive pulmonary disease...
January 19, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29194526/bacterial-infections-after-burn-injuries-impact-of-multidrug-resistance
#12
Anne M Lachiewicz, Christopher G Hauck, David J Weber, Bruce A Cairns, David van Duin
Patients who are admitted to the hospital after sustaining a large burn injury are at high risk for developing hospital-associated infections. If patients survive the initial 72 hours after a burn injury, infections are the most common cause of death. Ventilator-associated pneumonia is the most important infection in this patient population. The risk of infections caused by multidrug-resistant bacterial pathogens increases with hospital length of stay in burn patients. In the first days of the postburn hospitalization, more susceptible, Gram-positive organisms predominate, whereas later more resistant Gram-negative organisms are found...
November 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29193531/high-voltage-electrical-injury-modified-surgical-technique-for-optimal-defect-closuring-of-extra-large-cranial-defect
#13
S S Prodanov, E G Benkova, A A Chokoeva
Electrical burns are group of traumatic injuries with a mortality rate of 3-15%. High-voltage induced extensive electric burns are rarely seen in the cranial area, compared to upper and lower limbs, but extremely difficult for treatment, due to the limited flexibility in this area. The spectrum of therapeutic interventions in electrical burns in general, evolving initial necrectomy, decompression, and aggressive debridement with early skin coverage is usually not enough in cases of extensive cranial defects...
November 28, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/29190735/subgroup-analysis-of-continuous-renal-replacement-therapy-in-severely-burned-patients
#14
Jaechul Yoon, Youngmin Kim, Dohern Kym, Jun Hur, Haejun Yim, Yong-Suk Cho, Wook Chun
Continuous renal replacement therapy (CRRT) is administered to critically ill patients with renal injuries as renal replacement or renal support. We aimed to identify predictors of mortality among burn patients receiving CRRT, and to investigate clinical differences according to acute kidney injury (AKI) status. This retrospective observational study evaluated 216 Korean burn patients who received CRRT at a burn intensive care unit. Patients were categorized by AKI status. Data were collected regarding arterial pH, laboratory results, ratio of arterial oxygen partial pressure to fractional inspired oxygen (PF ratio), and urine production...
2017: PloS One
https://www.readbyqxmd.com/read/29188163/notalgia-paresthetica-a-novel-approach-to-treatment-with-cryolipolysis
#15
REVIEW
Philip R Cohen
Notalgia paresthetica, a neurosensory syndrome that typically occurs on the upper back, has multiple clinical symptoms with variable degrees of expression in each individual afflicted with the condition. The involved site is usually hyperpigmented and is associated with burning, coldness, hypoesthesia, increased pain, pruritus and/or tingling. In the affected area, the number of nerve fibers may be increased and the cutaneous sensory nerves are altered secondary to localized impingement, central injury, or both...
September 28, 2017: Curēus
https://www.readbyqxmd.com/read/29187917/multi-antibiotic-resistant-extended-spectrum-beta-lactamase-producing-bacteria-pose-a-challenge-to-the-effective-treatment-of-wound-and-skin-infections
#16
Angus Nnamdi Oli, Dennis Emeka Eze, Thaddeus Harrison Gugu, Ifeanyi Ezeobi, Ukamaka Nwakaku Maduagwu, Chibueze Peter Ihekwereme
Introduction: The increasing incidence of antibiotic resistant bacteria is a concern both to the clinicians and the patients due to obvious consequences such as treatment failures, prolonged patients' stay in hospital and nosocomial infections. The choice of the first antibiotic therapy in emergency wards in hospitals is usually not based on patient-specific microbial culture and susceptibility test result.This study is aimed at profiling extended-spectrum beta-lactamase (ESBL) producing bacteria associated with wound injuries and highlighting their multi-antibiotic resistance character...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29187346/influence-of-early-childhood-burns-on-school-performance-an-australian-population-study
#17
Nadin Azzam, Ju-Lee Oei, Susan Adams, Barbara Bajuk, Lisa Hilder, Abdel-Latif Mohamed, Ian M R Wright, Andrew J A Holland
OBJECTIVES: To determine the influence of burn injuries on childhood performance in national standardised curriculum-based school tests. DESIGN: Birth and health records of 977 children who were hospitalised with a burn injury between 2000 and 2006 in the state of New South Wales, Australia, were linked to performance scores in the National Assessment Program: Literacy and Numeracy test, a compulsory nationwide curriculum-based test (CBT) and compared with children who were not hospitalised for burns and who were matched for birth year, gender, gestation and socioeconomic status...
November 29, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29183751/the-impact-of-work-related-burn-injury-on-social-reintegration-outcomes-a-life-impact-burn-recovery-evaluation-libre-study
#18
Jeffrey C Schneider, Vivian L Shie, Leda Espinoza, Gabriel D Shapiro, Austin Lee, Amy Acton, Molly Marino, Alan Jette, Lewis E Kazis, Colleen M Ryan
OBJECTIVE: To examine differences in long-term social reintegration outcomes for burn survivors with and without work-related injuries. DESIGN: Cross-sectional survey. SETTING: Community-dwelling burn survivors. PARTICIPANTS: Burn survivors (N = 601) aged ≥18 years with injuries ≥5% total body surface area or burns to critical areas (hands, feet, face, or genitals). INTERVENTIONS: Not applicable...
November 25, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29178943/high-volume-hemofiltration-in-adult-burn-patients-with-septic-shock-and-acute-kidney-injury-a-multicenter-randomized-controlled-trial
#19
Kevin K Chung, Elsa C Coates, David J Smith, Rachel A Karlnoski, William L Hickerson, Angela L Arnold-Ross, Michael J Mosier, Marcia Halerz, Amy M Sprague, Robert F Mullins, Daniel M Caruso, Marlene Albrecht, Brett D Arnoldo, Agnes M Burris, Sandra L Taylor, Steven E Wolf
BACKGROUND: Sepsis and septic shock occur commonly in severe burns. Acute kidney injury (AKI) is also common and often results as a consequence of sepsis. Mortality is unacceptably high in burn patients who develop AKI requiring renal replacement therapy and is presumed to be even higher when combined with septic shock. We hypothesized that high-volume hemofiltration (HVHF) as a blood purification technique would be beneficial in this population. METHODS: We conducted a multicenter, prospective, randomized, controlled clinical trial to evaluate the impact of HVHF on the hemodynamic profile of burn patients with septic shock and AKI involving seven burn centers in the United States...
November 25, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29178479/face-allotransplantation-for-various-types-of-facial-disfigurements-a-series-of-five-cases
#20
Ömer Özkan, Özlenen Özkan, Mehmetcan Ubur, Necmiye Hadimioğlu, Melike Cengiz, İsmail Afşar
BACKGROUND: The aim of this report is to present our long-term experiences with a series of 5 face-transplanted patients in terms of surgical aspects and postoperative outcomes, and to describe possible salvage strategies in case of difficulties. METHODS: Five patients, 4 receiving full-face transplantation and 1 undergoing partial transplantation at our institution were included. The patients were aged between 19 and 54 years. Two had extensive burn scars to the face, and 3 had suffered gunshot injuries...
November 27, 2017: Microsurgery
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