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https://www.readbyqxmd.com/read/29128996/e-derma-a-novel-wireless-dermatoscopy-system
#1
Bogdan Dugonik, A Dugonik, D Horvat, B Žalik, D Špelič
Cutaneous Melanoma (CM) is a malignant tumour, and is one of the most rapidly growing cancers. Discovering a melanoma in the early stages of the disease is extremely difficult and, as such, only an invasive disease stage can be identified easily with the naked eye. Dermatoscopy is a diagnostic method intended to maximise early detection of CM performed by the dermatoscopy system. To address the limitations of existing systems a novel, wireless digital dermatoscopy system is presented for providing high-resolution images...
November 11, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29125645/advanced-plasmonic-materials-for-dynamic-color-display
#2
REVIEW
Lei Shao, Xiaolu Zhuo, Jianfang Wang
Plasmonic structures exhibit promising applications in high-resolution and durable color generation. Research on advanced hybrid plasmonic materials that allow dynamically reconfigurable color control has developed rapidly in recent years. Some of these results may give rise to practically applicable reflective displays in living colors with high performance and low power consumption. They will attract broad interest from display markets, compared with static plasmonic color printing, for example, in applications such as digital signage, full-color electronic paper, and electronic device screens...
November 10, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29108815/non-invasive-blood-pressure-monitoring-in-the-critically-ill-time-to-abandon-the-intra-arterial-catheter
#3
REVIEW
Karim Lakhal, Stephan Ehrmann, Thierry Boulain
Although its reliability is often questioned, non-invasive blood pressure (NIBP) monitoring with an oscillometric arm cuff is widely used, even in shocked critically ill patients. When correctly implemented, modern arm NIBP devices actually can provide accurate and precise measurements of mean blood pressure as well as clinically meaningful information such as identification of hypo- and hypertensive patients and monitoring of response to therapy. Even in specific circumstances such as arrhythmia, hypotension, vasopressor infusion and possibly in obese patients, arm NIBP could be useful, contrary to widespread belief...
November 3, 2017: Chest
https://www.readbyqxmd.com/read/29093045/children-s-privacy-in-the-big-data-era-research-opportunities
#4
REVIEW
Kathryn C Montgomery, Jeff Chester, Tijana Milosevic
This article focuses on the privacy implications of advertising on social media, mobile apps, and games directed at children. Academic research on children's privacy has primarily focused on the safety risks involved in sharing personal information on the Internet, leaving market forces (such as commercial data collection) as a less discussed aspect of children's privacy. Yet, children's privacy in the digital era cannot be fully understood without examining marketing practices, especially in the context of "big data...
November 2017: Pediatrics
https://www.readbyqxmd.com/read/29093042/digital-media-and-risks-for-adolescent-substance-abuse-and-problematic-gambling
#5
REVIEW
Dan Romer, Megan Moreno
Digital media provide increased opportunities for both marketing and social transmission of risky products and behavior. We briefly review what is known about adolescent exposure to favorable presentations of addictive substances, such as alcohol, tobacco, and marijuana, as well as behaviors such as gambling, on social and other online media. Our understanding of these influences and whether they require greater regulation is still developing, and recommendations for future research to address these gaps in our understanding are described...
November 2017: Pediatrics
https://www.readbyqxmd.com/read/29093041/screen-media-exposure-and-obesity-in-children-and-adolescents
#6
REVIEW
Thomas N Robinson, Jorge A Banda, Lauren Hale, Amy Shirong Lu, Frances Fleming-Milici, Sandra L Calvert, Ellen Wartella
Obesity is one of the best-documented outcomes of screen media exposure. Many observational studies find relationships between screen media exposure and increased risks of obesity. Randomized controlled trials of reducing screen time in community settings have reduced weight gain in children, demonstrating a cause and effect relationship. Current evidence suggests that screen media exposure leads to obesity in children and adolescents through increased eating while viewing; exposure to high-calorie, low-nutrient food and beverage marketing that influences children's preferences, purchase requests, consumption habits; and reduced sleep duration...
November 2017: Pediatrics
https://www.readbyqxmd.com/read/29044670/the-effect-of-blue-light-blocking-spectacle-lenses-on-visual-performance-macular-health-and-the-sleep-wake-cycle-a%C3%A2-systematic-review-of-the-literature
#7
REVIEW
John G Lawrenson, Christopher C Hull, Laura E Downie
PURPOSE: Blue-blocking (BB) spectacle lenses, which attenuate short-wavelength light, are being marketed to alleviate eyestrain and discomfort when using digital devices, improve sleep quality and potentially confer protection from retinal phototoxicity. The aim of this review was to investigate the relative benefits and potential harms of these lenses. METHODS: We included randomised controlled trials (RCTs), recruiting adults from the general population, which investigated the effect of BB spectacle lenses on visual performance, symptoms of eyestrain or eye fatigue, changes to macular integrity and subjective sleep quality...
November 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28982136/augmentation-of-vamp-catalytic-activity-of-botulinum-neurotoxin-serotype-b-does-not-result-in-increased-potency-in-physiological-systems
#8
Mark Elliott, Jacquie Maignel, Sai Man Liu, Christine Favre-Guilmard, Imran Mir, Paul Farrow, Fraser Hornby, Sandra Marlin, Shilpa Palan, Matthew Beard, Johannes Krupp
Botulinum neurotoxins (BoNTs) are used extensively as therapeutic agents. Serotypes A and B are available as marketed products. Higher doses of BoNT/B are required to reach an efficacy similar to that of products containing BoNT/A. Advances in our understanding of BoNT/B mechanism of action have afforded the opportunity to make rational modifications to the toxin aimed at increasing its activity. Recently, a mutation in the light chain of BoNT/B (S201P) was described that increases the catalytic activity of the isolated BoNT/B light chain in biochemical assays...
2017: PloS One
https://www.readbyqxmd.com/read/28981454/hybrid-sequencing-of-full-length-cdna-transcripts-of-stems-and-leaves-in-dendrobium-officinale
#9
Liu He, Shuhua Fu, Zhichao Xu, Jun Yan, Jiang Xu, Hong Zhou, Jianguo Zhou, Xinlian Chen, Ying Li, Kin Fai Au, Hui Yao
Dendrobium officinale is an extremely valuable orchid used in traditional Chinese medicine, so sought after that it has a higher market value than gold. Although the expression profiles of some genes involved in the polysaccharide synthesis have previously been investigated, little research has been carried out on their alternatively spliced isoforms in D. officinale. In addition, information regarding the translocation of sugars from leaves to stems in D. officinale also remains limited. We analyzed the polysaccharide content of D...
October 5, 2017: Genes
https://www.readbyqxmd.com/read/28980020/-digital-electroencephalography-in-brain-death-diagnostics-technical-requirements-and-results-of-a%C3%A2-survey-on-the-compatibility-with-medical-guidelines-of-digital-eeg-systems-from-providers-in-germany
#10
U Walter, S Noachtar, H Hinrichs
BACKGROUND: The guidelines of the German Medical Association and the German Society for Clinical Neurophysiology and Functional Imaging (DGKN) require a high procedural and technical standard for electroencephalography (EEG) as an ancillary method for diagnosing the irreversible cessation of brain function (brain death). Nowadays, digital EEG systems are increasingly being applied in hospitals. So far it is unclear to what extent the digital EEG systems currently marketed in Germany meet the guidelines for diagnosing brain death...
October 4, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28972409/endoscope-i-an-innovation-in-mobile-endoscopic-technology-transforming-the-delivery-of-patient-care-in-otolaryngology
#11
N Mistry, C Coulson, A George
Digital and mobile device technology in healthcare is a growing market. The introduction of the endoscope-i, the world's first endoscopic mobile imaging system, allows the acquisition of high definition images of the ear, nose and throat (ENT). The system combines the e-i Pro camera app with a bespoke engineered endoscope-i adaptor which fits securely onto the iPhone or iPod touch. Endoscopic examination forms a salient aspect of the ENT work-up. The endoscope-i therefore provides a mobile and compact alternative to the existing bulky endoscopic systems currently in use which often restrict the clinician to the clinic setting...
October 17, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28969277/effect-of-different-composite-restorations-on-the-cuspal-deflection-of-premolars-restored-with-different-insertion-techniques-an-in-vitro-study
#12
Sakshi Singhal, Anuraag Gurtu, Anurag Singhal, Rashmi Bansal, Sumit Mohan
INTRODUCTION: This study was conducted to assess the effect of different composite materials on the cuspal deflection of premolars restored with bulk placement of resin composite in comparison to horizontal incremental placement and modified tangential incremental placement. AIM: The aim of this study was to evaluate the cuspal deflection caused by different composite materials when different insertion techniques were used. MATERIALS AND METHODS: Two different composite materials were used that is Tetric N Ceram (Ivoclar Vivadent marketing, India) and SonicFill(TM) (Kerr Sybron Dental)...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28963826/-italian-health-centers-and-web-marketing-strategy-necessary-improvements-even-in-nephrology
#13
Maria Rinaldi Miliani, Antonio Barracca, Giuseppe Quintaliani
The complete digitalization of the health system is an objective that Italy, from 2014, is pursuing with great difficulty, spurred by the many European initiatives dedicated to it. Despite the social and cultural background seems to be clearly ready for an application of the renewal strategies, e-Health and m-Health are struggling to get off the ground throughout the territory. The main difficulties are find at local level and don't spare any medical discipline, nephrology included. The characteristics of the official websites belonging to the local health centers demonstrate it...
September 28, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28944579/morphological-criteria-of-feminine-upper-eyelashes-quantified-by-a-new-semi-automatized-image-analysis-application-to-the-objective-assessment-of-mascaras
#14
A Shaiek, F Flament, G François, M Vicic, S Cointereau-Chardron, E Curval, S Canevet-Zaida, O Coubard, Y Idelcaid
BACKGROUND: The wide diversity of feminine eyelashes in shape, length, and curvature makes it a complex domain that remains to be quantified in vivo, together with their changes brought by application of mascaras that are visually assessed by women themselves or make-up experts. METHODS: A dedicated software was developed to semi-automatically extract and quantify, from digital images (frontal and lateral pictures), the major parameters of feminine eyelashes of Mexican and Caucasian women and to record the changes brought by the applications of various mascaras and their brushes, being self or professionally applied...
September 24, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28895231/software-related-recalls-of-health-information-technology-and-other-medical-devices-implications-for-fda-regulation-of-digital-health
#15
Jay G Ronquillo, Diana M Zuckerman
Policy Points: Medical software has become an increasingly critical component of health care, yet the regulation of these devices is inconsistent and controversial. No studies of medical devices and software assess the impact on patient safety of the FDA's current regulatory safeguards and new legislative changes to those standards. Our analysis quantifies the impact of software problems in regulated medical devices and indicates that current regulations are necessary but not sufficient for ensuring patient safety by identifying and eliminating dangerous defects in software currently on the market...
September 2017: Milbank Quarterly
https://www.readbyqxmd.com/read/28830112/infectious-disease-surveillance-in-the-big-data-era-towards-faster-and-locally-relevant-systems
#16
REVIEW
Lone Simonsen, Julia R Gog, Don Olson, Cécile Viboud
While big data have proven immensely useful in fields such as marketing and earth sciences, public health is still relying on more traditional surveillance systems and awaiting the fruits of a big data revolution. A new generation of big data surveillance systems is needed to achieve rapid, flexible, and local tracking of infectious diseases, especially for emerging pathogens. In this opinion piece, we reflect on the long and distinguished history of disease surveillance and discuss recent developments related to use of big data...
December 1, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28819142/development-and-inter-laboratory-assessment-of-droplet-digital-pcr-assays-for-multiplex-quantification-of-15-genetically-modified-soybean-lines
#17
Alexandra Bogožalec Košir, Bjørn Spilsberg, Arne Holst-Jensen, Jana Žel, David Dobnik
Quantification of genetically modified organisms (GMOs) in food and feed products is often required for their labelling or for tolerance thresholds. Standard-curve-based simplex quantitative polymerase chain reaction (qPCR) is the prevailing technology, which is often combined with screening analysis. With the rapidly growing number of GMOs on the world market, qPCR analysis becomes laborious and expensive. Innovative cost-effective approaches are therefore urgently needed. Here, we report the development and inter-laboratory assessment of multiplex assays to quantify GMO soybean using droplet digital PCR (ddPCR)...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28812471/effectiveness-and-tolerability-of-parenteral-testosterone-undecanoate-a-post-marketing-surveillance-study
#18
Jan Wolf, Dieter Keipert, Heiko Motazedi, Michael Ernst, Joanne Nettleship, Louis Gooren
This observational post-marketing study of parenteral testosterone undecanoate (TU) in a non-selected population aimed to: examine the effectiveness of TU as treatment of hypogonadism; record adverse drug reactions (ADR) quantitatively particularly regarding polycythemia, prostate safety and cardiovascular-related metabolic risk factors; and verify whether recommended injection intervals apply to routine clinical practice. Eight hundred and seventy subjects from 259 outpatient units scheduled to visit the clinic six times were included...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28773208/preparation-and-characterization-of-soybean-oil-based-polyurethanes-for-digital-doming-applications
#19
Vincenzo Pantone, Amelita Grazia Laurenza, Cosimo Annese, Roberto Comparelli, Francesco Fracassi, Paola Fini, Angelo Nacci, Antonella Russo, Caterina Fusco, Lucia D'Accolti
Polyurethane-resin doming is currently one of the fastest growing markets in the field of industrial graphics and product identification. Semi-rigid bio-based polyurethanes were prepared deriving from soybean oil as a valuable alternative to fossil materials for digital doming and applied to digital mosaic technology. Bio-resins produced can favorably compete with the analogous fossil polymers, giving high-quality surface coatings (ascertained by SEM analyses). In addition, polyurethane synthesis was accomplished by using a mercury- and tin-free catalyst (the commercially available zinc derivative K22) bringing significant benefits in terms of cost efficiency and eco-sustainability...
July 25, 2017: Materials
https://www.readbyqxmd.com/read/28756767/beyond-pilotitis-taking-digital-health-interventions-to-the-national-level-in-china-and-uganda
#20
REVIEW
Fei Huang, Sean Blaschke, Henry Lucas
BACKGROUND: Innovation theory has focused on the adoption of new products or services by individuals and their market-driven diffusion to the population at large. However, major health sector innovations typically emerge from negotiations between diverse stakeholders who compete to impose or at least prioritise their preferred version of that innovation. Thus, while many digital health interventions have succeeded in terms of adoption by a substantial number of providers and patients, they have generally failed to gain the level of acceptance required for their integration into national health systems that would promote sustainability and population-wide application...
July 31, 2017: Globalization and Health
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