keyword
MENU ▼
Read by QxMD icon Read
search

Functional MRI

keyword
https://www.readbyqxmd.com/read/28343127/direct-immobilization-of-manganese-chelates-on-silica-nanospheres-for-mri-applications
#1
Marcell Pálmai, Adrienn Pethő, Lívia Naszályi Nagy, Szilvia Klébert, Zoltán May, Judith Mihály, András Wacha, Katalin Jemnitz, Zsuzsanna Veres, Ildikó Horváth, Krisztián Szigeti, Domokos Máthé, Zoltán Varga
The development of tissue specific magnetic resonance imaging (MRI) contrast agents (CAs) is very desirable to achieve high contrast ratio combined with excellent anatomical details. To this end, we introduce a highly effective manganese(II) containing silica material, with the aim to shorten the longitudinal (T1) relaxation time. The microporous silica nanospheres (MSNSs) with enlarged porosity and specific surface area were prepared by a surfactant assisted aqueous method. Subsequently, the surface silanol groups were amino-functionalized, reacted with diethylenetriaminepentaacetic (DTPA) dianhydride and finally deposited with Mn(2+)...
March 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28343018/cus-as-a-gatekeeper-of-mesoporous-upconversion-nanoparticles-based-drug-controlled-release-system-for-tumor-targeted-multimodal-imaging-and-synergetic-chemo-thermotherapy
#2
Xiangjie Su, Feifei Zhao, Yuhui Wang, Xiaosa Yan, Shaona Jia, Bin Du
In this work, a tumor-targeted multifunctional mesoporous upconversion nanoparticle-based drug controlled release system was developed for UCL/MRI/PAT guided synergetic chemo- thermotherapy. Herein, the core-shell mesoporous upconversion nanoparticles served as drug carrier exhibiting higher upconversion luminescence emission intensity, with CuS as a gatekeeper through a cleavable disulfide bond under the influence of glutathione. CuS could not only prevent drug from early release during the delivery but also improve the delivery system function with the ability of photothermal therapy and photoacoustic tomography...
March 22, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28342819/ankylosis-of-the-knee-after-septic-arthritis-following-anterior-cruciate-ligament-reconstruction-in-a-13-year-old-male
#3
Bastian Mester, Falk Ullerich, Tobias Ohmann, Martin Glombitza, Christian Schoepp
We present the case of an adolescent male developing anankylosis of the knee after septic arthritis following anterior cruciate ligamentreconstruction (ACLR).The patientwas shifted to our institutionwithpostoperative septic arthritis associated with a systemic septic condition. Before, repeated arthroscopic surgery had beenconductedwithoutany improvement. MRI showed a concomitant osteomyelitis. The infection (Gächter IV, S. aureus) was controlled by an open surgical approach and graft removal.An increasing joint stiffness wasdocumented...
March 22, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28342532/shear-scaling-based-approach-for-irreversible-energy-loss-estimation-in-stenotic-aortic-flow-an-in-vitro-study
#4
Utku Gülan, Christian Binter, Sebastian Kozerke, Markus Holzner
Today, the functional and risk assessment of stenosed arteries is mostly based on ultrasound Doppler blood flow velocity measurements or catheter pressure measurements, which rely on several assumptions. Alternatively, blood velocity including turbulent kinetic energy (TKE) may be measured using MRI. The aim of the present study is to validate a TKE-based approach that relies on the fact that turbulence production is dominated by the flow's shear to determine the total irreversible energy loss from MRI scans...
March 12, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28340447/fronto-limbic-disconnection-in-depressed-patients-with-suicidal-ideation-a-resting-state-functional-connectivity-study
#5
Lian Du, Jinkun Zeng, Huan Liu, Dejian Tang, Huaqing Meng, Yongmei Li, Yixiao Fu
BACKGROUND: Suicidal ideation (SI) is highly prevalent and a known symptom of Major Depressive Disorder (MDD), but its underlying biological mechanisms are relatively unknown. Several studies linked suicidal ideation to dysfunctional brain circuits, specifically fronto-limbic connections. The purpose of this work was to investigate fronto-limbic disconnection in MDD patients with or without SI. METHODS: MDD patients with SI (SI, n=28) or without SI (NSI, n=20), identified by the Scale for Suicide Ideation and healthy controls (HCs, n=30) underwent resting-state functional MRI scanning...
February 21, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28339663/cardiac-involvement-in-granulomatosis-with-polyangiitis-a-magnetic-resonance-imaging-study-of-31-consecutive-patients
#6
Grégory Pugnet, Hervé Gouya, Xavier Puéchal, Benjamin Terrier, André Kahan, Paul Legmann, Loïc Guillevin, Olivier Vignaux
Objectives.: Specific cardiac involvement in granulomatosis with polyangiitis (GPA) is probably underestimated since many of these conditions are subclinical. The objective of this study was to assess the prevalence and patterns of cardiac abnormalities detected by cardiac MRI (CMRI) in patients with GPA. Methods.: Thirty-one consecutive patients with newly diagnosed or relapsing GPA underwent CMRI to assess morphological, functional, perfusion at rest and delayed enhancement abnormalities...
February 16, 2017: Rheumatology
https://www.readbyqxmd.com/read/28339428/does-conservative-treatment-change-the-brain-in-patients-with-chronic-musculoskeletal-pain-a-systematic-review
#7
Jeroen Kregel, Iris Coppieters, Robby DePauw, Anneleen Malfliet, Lieven Danneels, Jo Nijs, Barbara Cagnie, Mira Meeus
BACKGROUND: Chronic musculoskeletal pain is characterized by maladaptive central neuroplastic changes. Many observational studies have demonstrated that chronic pain states are associated with brain alterations regarding structure and/or function. Rehabilitation of patients with chronic musculoskeletal pain may include cognitive, exercise, or multimodal therapies. OBJECTIVE: The current review aims to provide a constructive overview of the existing literature reporting neural correlates, based on brain magnetic resonance imaging (MRI) techniques, following conservative treatment in chronic musculoskeletal pain patients...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28339189/polymerization-induced-self-assembly-pisa-control-over-the-morphology-of-19f-containing-polymeric-nano-objects-for-cell-uptake-and-tracking
#8
Wei Zhao, Hang Thu Ta, Cheng Zhang, Andrew Keith Whittaker
Fluorine-containing polymeric materials are receiving increasing attention as imaging probes in fluorine-19 magnetic resonance imaging (19F MRI), for example to enable quantitative in vivo detection of cells. Here we describe the one-pot polymerization synthesis of 19F-containing functional poly(OEGA-co-TFEA)-b-poly(St-co-VBA) copolymers as a new class of fluorinated MRI agent. A range of nanoparticle morphologies, including spheres, worm-like particles and vesicles were formed as a consequence of polymerization-induced self-assembly (PISA)...
March 24, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28338783/empathy-and-moral-emotions-in-post-apartheid-south-africa-an-fmri-investigation
#9
Melike M Fourie, Dan J Stein, Mark Solms, Pumla Gobodo-Madikizela, Jean Decety
Moral emotions elicited in response to others' suffering are mediated by empathy and affect how we respond to their pain. South Africa provides a unique opportunity to study group processes given its racially divided past. The present study seeks insights into aspects of the moral brain by investigating behavioral and functional MRI responses of White and Black South Africans who lived through apartheid to in- and out-group physical and social pain. Whereas the physical pain task featured faces expressing dynamic suffering, the social pain task featured victims of apartheid violence from the South African Truth and Reconciliation Commission to elicit heartfelt emotion...
February 17, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28338417/a-3d-tissue-printing-approach-for-validation-of-diffusion-tensor-imaging-in-skeletal-muscle
#10
David B Berry, Shangting You, John Warner, Lawrence R Frank, Shaochen Chen, Samuel R Ward
The ability to noninvasively assess skeletal muscle microstructure, which predicts function and disease, would be of significant clinical value. One method that holds this promise is diffusion tensor magnetic resonance imaging (DT-MRI), which is sensitive to the microscopic diffusion of water within tissues and has become ubiquitous in neuroimaging as a way of assessing neuronal structure and damage. However, its application to the assessment of changes in muscle microstructure associated with injury, pathology, or age remains poorly defined, because it is difficult to precisely control muscle microstructural features in vivo...
March 24, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28337941/lesion-symptom-map-of-cognitive-postural-interference-in-multiple-sclerosis
#11
Serena Ruggieri, Fulvia Fanelli, Letizia Castelli, Nikolaos Petsas, Laura De Giglio, Luca Prosperini
OBJECTIVE: To investigate the disease-altered structure-function relationship underlying the cognitive-postural interference (CPI) phenomenon in multiple sclerosis (MS). METHODS: We measured postural sway of 96 patients and 48 sex-/age-matched healthy controls by force platform in quiet standing (single-task (ST)) while performing the Stroop test (dual-task (DT)) to estimate the dual-task cost (DTC) of balance. In patient group, binary T2 and T1 lesion masks and their corresponding lesion volumes were obtained from magnetic resonance imaging (MRI) of brain...
March 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28337782/three-dimensional-oxygen-enhanced-mri-of-the-human-lung-at-1-5t-with-ultra-fast-balanced-steady-state-free-precession
#12
Orso Pusterla, Grzegorz Bauman, Oliver Bieri
PURPOSE: To assess the feasibility of 3D oxygen-enhanced (OE) MRI of the lung at 1.5T using multi-volumetric ultra-fast balanced steady-state free precession (ufSSFP) acquisitions. METHODS: Isotropic imaging of the lung for OE-MRI was performed with an adapted 3D ufSSFP sequence using five breath-hold acquisitions ranging from functional residual capacity to tidal inspiration under both normoxic (room air) and hyperoxic (100% O2 ) gas conditions. For each O2 concentration, a sponge model (which captures the parenchymal signal intensity variation as a function of the lung volume) was fitted to the acquired multi-volumetric datasets after semiautomatic lung segmentation and deformable image registration...
March 24, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28337609/trans-eyebrow-supraorbital-approach-in-large-suprasellar-craniopharyngioma-surgery-in-adults-analysis-of-optic-nerve-length-and-extent-of-tumor-resection-original-article
#13
Ricardo Prat, Inma Galeano, Rocío Evangelista, Giovanni Pancucci, Juliana Guarín, Angel Ayuso, Mukesh Misra
BACKGROUND: One of the main drawbacks in the surgery of large craniopharyngiomas is the presence of a prefixed optic chiasm. Our main objective in this study is to compare the predictive value of the optic nerve length and optic chiasm location on large craniopharyngiomas' extent of resection. METHOD: We retrospectively studied 21 consecutive patients with large craniopharyngiomas who underwent tumor resection through the trans-eyebrow supraorbital approach. Clinical and radiological findings on preoperative MRI were recorded, including the optic chiasm location classified as prefixed, postfixed or normal...
March 23, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28337409/network-degeneration-and-dysfunction-in-presymptomatic-c9orf72-expansion-carriers
#14
Suzee E Lee, Ana C Sias, Maria Luisa Mandelli, Jesse A Brown, Alainna B Brown, Anna M Khazenzon, Anna A Vidovszky, Theodore P Zanto, Anna M Karydas, Mochtar Pribadi, Deepika Dokuru, Giovanni Coppola, Dan H Geschwind, Rosa Rademakers, Maria Luisa Gorno-Tempini, Howard J Rosen, Bruce L Miller, William W Seeley
Hexanucleotide repeat expansions in C9ORF72 are the most common known genetic cause of familial and sporadic frontotemporal dementia and amyotrophic lateral sclerosis. Previous work has shown that patients with behavioral variant frontotemporal dementia due to C9ORF72 show salience and sensorimotor network disruptions comparable to those seen in sporadic behavioral variant frontotemporal dementia, but it remains unknown how early in the lifespan these and other changes in brain structure and function arise...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28336868/eu-gd-codoped-yttria-nanoprobes-for-optical-and-t%C3%A2-weighted-magnetic-resonance-imaging
#15
Timur Sh Atabaev, Jong Ho Lee, Yong Cheol Shin, Dong-Wook Han, Ki Seok Choo, Ung Bae Jeon, Jae Yeon Hwang, Jeong A Yeom, Hyung-Kook Kim, Yoon-Hwae Hwang
Nanoprobes with multimodal functionality have attracted significant interest recently because of their potential applications in nanomedicine. This paper reports the successful development of lanthanide-doped Y₂O₃ nanoprobes for potential applications in optical and magnetic resonance (MR) imaging. The morphology, structural, and optical properties of these nanoprobes were characterized by transmission electron microscope (TEM), field emission scanning electron microscope (FESEM), X-ray diffraction (XRD), energy-dispersive X-ray (EDX), and photoluminescence (PL)...
February 10, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28336782/functional-imaging-signature-of-patients-presenting-with-polycythemia-paraganglioma-syndromes
#16
Ingo Janssen, Clara Chi Chen, Zhenping Zhuang, Corina M Millo, Katherine Wolf, Alexander Ling, Frank I Lin, Karen T Adams, Peter Herscovitch, Richard A Feelders, Antonio T Fojo, David Taieb, Electron Kebebew, Karel Pacak
Rationale: Pheochromocytoma/paraganglioma (PPGL) syndromes associated with polycythemia have previously been described in association with mutations in the von Hippel-Lindau (VHL) gene. Recently, mutations in the prolyl hydroxylase gene (PHD) 1 and 2 and in the hypoxia-inducible factor 2 alpha (HIF2A) were also found to be associated with multiple and recurrent PPGL. Such patients also presented with PPGL and polycythemia, and later on, some presented with duodenal somatostatinoma. In additional patients presenting with PPGL and polycythemia, no further mutations have been discovered...
March 23, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28336499/radical-resection-of-the-pancreas-should-not-always-be-necessary-in-the-surgical-management-of-pancreatic-solid-pseudopapillary-tumor-in-children
#17
Emre Divarcı, Zafer Dökümcü, Nazan Çetingül, Deniz Nart, Funda Yılmaz Barbet, Orkan Ergün, Ahmet Çelik
BACKGROUND/AIMS: Pancreatic solid pseudopapillary tumor (SPT) is a rare neoplasm in children. In this study, we aimed to present our surgical strategy based on minimal resection by enucleation or limited resection in localized pancreatic SPT. MATERIALS AND METHODS: We retrospectively analyzed the medical records of children who underwent surgical resection between October 2011 and September 2016. RESULTS: Five female patients with a median age of 15 years (range, 14-17 years) were operated...
March 23, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28335622/functional-connectivity-of-the-subcallosal-cingulate-cortex-and-differential-outcomes-to-treatment-with-cognitive-behavioral-therapy-or-antidepressant-medication-for-major-depressive-disorder
#18
Boadie W Dunlop, Justin K Rajendra, W Edward Craighead, Mary E Kelley, Callie L McGrath, Ki Sueng Choi, Becky Kinkead, Charles B Nemeroff, Helen S Mayberg
OBJECTIVE: The purpose of this article was to inform the first-line treatment choice between cognitive-behavioral therapy (CBT) or an antidepressant medication for treatment-naive adults with major depressive disorder by defining a neuroimaging biomarker that differentially identifies the outcomes of remission and treatment failure to these interventions. METHOD: Functional MRI resting-state functional connectivity analyses using a bilateral subcallosal cingulate cortex (SCC) seed was applied to 122 patients from the Prediction of Remission to Individual and Combined Treatments (PReDICT) study who completed 12 weeks of randomized treatment with CBT or antidepressant medication...
March 24, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28335193/facile-synthesis-of-gd-functionalized-gold-nanoclusters-as-potential-mri-ct-contrast-agents
#19
Wenjun Le, Shaobin Cui, Xin Chen, Huanhuan Zhu, Bingdi Chen, Zheng Cui
Multi-modal imaging plays a key role in the earlier detection of disease. In this work, a facile bioinspired method was developed to synthesize Gd-functionalized gold nanoclusters (Gd-Au NCs). The Gd-Au NCs exhibit a uniform size, with an average size of 5.6 nm in dynamic light scattering (DLS), which is a bit bigger than gold clusters (3.74 nm, DLS), while the fluorescent properties of Gd-Au NCs are almost the same as that of Au NCs. Moreover, the Gd-Au NCs exhibit a high longitudinal relaxivity value (r1) of 22...
April 9, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334998/spatiotemporal-mapping-of-epileptic-spikes-using-simultaneous-eeg-functional-mri
#20
Jennifer M Walz, Mangor Pedersen, Amir Omidvarnia, Mira Semmelroch, Graeme D Jackson
Epileptic spikes occur on the sub-second timescale and are known to involve not only epileptic foci but also large-scale distributed brain networks. There is likely to be a sequence of neural activity in multiple brain regions that occurs within the duration of a single spike, but standard electroencephalography-functional magnetic resonance imaging analyses, which use only the timing of the spikes to model the functional magnetic resonance imaging data, cannot determine the sequence of these activations. Our aim in this study is to temporally resolve these spatial activations to observe the spatiotemporal dynamics of the spike-related neural activity at a sub-second timescale...
February 20, 2017: Brain: a Journal of Neurology
keyword
keyword
2447
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"