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https://www.readbyqxmd.com/read/28636969/human-virus-derived-small-rnas-can-confer-antiviral-immunity-in-mammals
#1
Yang Qiu, Yanpeng Xu, Yao Zhang, Hui Zhou, Yong-Qiang Deng, Xiao-Feng Li, Meng Miao, Qiang Zhang, Bo Zhong, Yuanyang Hu, Fu-Chun Zhang, Ligang Wu, Cheng-Feng Qin, Xi Zhou
RNA interference (RNAi) functions as a potent antiviral immunity in plants and invertebrates; however, whether RNAi plays antiviral roles in mammals remains unclear. Here, using human enterovirus 71 (HEV71) as a model, we showed HEV71 3A protein as an authentic viral suppressor of RNAi during viral infection. When the 3A-mediated RNAi suppression was impaired, the mutant HEV71 readily triggered the production of abundant HEV71-derived small RNAs with canonical siRNA properties in cells and mice. These virus-derived siRNAs were produced from viral dsRNA replicative intermediates in a Dicer-dependent manner and loaded into AGO, and they were fully active in degrading cognate viral RNAs...
June 20, 2017: Immunity
https://www.readbyqxmd.com/read/28636490/creating-inclusive-physical-activity-spaces-the-case-of-body-positive-yoga
#2
Andrew C Pickett, George B Cunningham
PURPOSE: Within the modern cultural climate, those in larger bodies face high levels of weight stigma, particularly in sport and physical activity spaces, which serves as a strong barrier to their participation. However, given the strong link between physical activity and general health and well-being for participants, it is important to explore strategies that encourage participation of these individuals. Thus, the current research examined strategies that physical activity instructors use to develop inclusive exercise spaces for all body sizes...
June 21, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/28633584/variation-of-alkaloid-contents-and-antimicrobial-activities-of-papaver-rhoeas-l-growing-in-turkey-and-northern-cyprus
#3
İlkcan Çoban, Gizem Gülsoy Toplan, Berna Özbek, Çağlayan Unsal Gürer, Günay Sarıyar
CONTEXT: Papaver rhoeas L. (Papaveraceae) corn poppy, widely distributed in Turkey, is used to make a cough syrup for children, as a tea for disturbed sleep, for pain relief and as a sedative in folk medicine. OBJECTIVE: Samples of P. rhoeas collected from eight different locations in Turkey and three from northern Cyprus were investigated for their alkaloid content and screened for their antimicrobial activities. MATERIALS AND METHODS: From the aerial parts of P...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28632171/a-new-privacy-preserving-handover-authentication-scheme-for-wireless-networks
#4
Changji Wang, Yuan Yuan, Jiayuan Wu
Handover authentication is a critical issue in wireless networks, which is being used to ensure mobile nodes wander over multiple access points securely and seamlessly. A variety of handover authentication schemes for wireless networks have been proposed in the literature. Unfortunately, existing handover authentication schemes are vulnerable to a few security attacks, or incur high communication and computation costs. Recently, He et al. proposed a handover authentication scheme PairHand and claimed it can resist various attacks without rigorous security proofs...
June 20, 2017: Sensors
https://www.readbyqxmd.com/read/28631817/application-of-high-resolution-melting-analysis-for-authenticity-testing-of-valuable-dendrobium-commercial-products
#5
Xiaoman Dong, Chao Jiang, Yuan Yuan, Daiyin Peng, Yuqin Luo, Yuyang Zhao, Luqi Huang
BACKGROUND: The accurate identification of botanical origin in commercial products is important to ensure food authenticity and safety for consumers. The Dendrobium species have long been commercialized as functional food supplements and herbal medicines in Asia. Three valuable Dendrobium species, namely Dendrobium officinale, D. huoshanense and D. moniliforme, are often mutually adulterated in trade products in pursuit of higher profit. RESULTS: In this paper, a rapid and reliable semi-quantitative method for identifying the botanical origin of Dendrobium products in terminal markets was developed using HRM (High-Resolution Melting) analysis with specific primer pairs to target the trnL-F region...
June 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28631071/oxidation-of-c18-hydroxy-polyunsaturated-fatty-acids-to-epoxide-or-ketone-by-catalase-related-hemoproteins-activated-with-iodosylbenzene
#6
Tarvi Teder, William E Boeglin, Alan R Brash
Small catalase-related hemoproteins with a facility to react with fatty acid hydroperoxides were examined for their potential mono-oxygenase activity when activated using iodosylbenzene. The proteins tested were a Fusarium graminearum 41 kD catalase hemoprotein (Fg-cat, gene FGSG_02217), a Pseudomonas fluorescens Pfl01 catalase (37.5 kD, accession number WP_011333788.1), and a Mycobacterium avium ssp. paratuberculosis 33 kD catalase (gene MAP-2744c). 13-Hydroxy-octadecenoic acids (which are normally unreactive) were selected as substrates because these enzymes react specifically with the corresponding 13S-hydroperoxides (Pakhomova et al...
June 19, 2017: Lipids
https://www.readbyqxmd.com/read/28630442/ir-sensitivity-enhancement-of-cmos-image-sensor-with-diffractive-light-trapping-pixels
#7
Sozo Yokogawa, Itaru Oshiyama, Harumi Ikeda, Yoshiki Ebiko, Tomoyuki Hirano, Suguru Saito, Takashi Oinoue, Yoshiya Hagimoto, Hayato Iwamoto
We report on the IR sensitivity enhancement of back-illuminated CMOS Image Sensor (BI-CIS) with 2-dimensional diffractive inverted pyramid array structure (IPA) on crystalline silicon (c-Si) and deep trench isolation (DTI). FDTD simulations of semi-infinite thick c-Si having 2D IPAs on its surface whose pitches over 400 nm shows more than 30% improvement of light absorption at λ = 850 nm and the maximum enhancement of 43% with the 540 nm pitch at the wavelength is confirmed. A prototype BI-CIS sample with pixel size of 1...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28629531/survey-of-traditional-dai-medicine-reveals-species-confusion-and-potential-safety-concerns-a-case-study-on-radix-clerodendri-japonicum
#8
Bao-Zhong Duan, Hai-Lan Fang, Xi-Wen Li, Lin-Fang Huang, Wang Ping, Shi-Lin Chen
The adulteration of herbal products is a threat to consumer safety. In the present study, we surveyed the species composition of commercial Radix Clerodendri Japonicum products using DNA barcoding as a supervisory method. A reference database for plant-material DNA-barcode was successfully constructed with 48 voucher samples from 12 Clerodendrum species. The database was used to identify 27 Radix Clerodendri Japonicum decoction piece samples purchased from drug stores and hospitals. The DNA sequencing results revealed that only 1 decoction piece (3...
June 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28623855/authentic-feminist-authenticity-and-feminist-identity-in-teenage-feminists-talk
#9
Octavia Calder-Dawe, Nicola Gavey
This article explores how young people's feminist identities take shape in conjunction with a contemporary ideal of personal authenticity: to know and to express the 'real me'. Drawing from interviews with 18 teenagers living in Auckland, New Zealand, we examine a novel convergence of authenticity and feminism in participants' identity talk. For social psychologists interested in identity and politics, this convergence is intriguing: individualizing values such as authenticity are generally associated with disengagement with structural critique and with a repudiation of politicized and activist identities...
June 17, 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/28623791/exposure-profile-of-volatile-organic-compounds-receptor-associated-with-paints-consumption
#10
Di Wang, Lei Nie, Xia Shao, Hongbing Yu
Epidemiologic studies regarding solvent-based paints (SBPs) containing VOCs have demonstrated a strong correlation between chronic and acute adverse health effects and the SBPs. Therefore, new environmentally friendly paints as substitutes containing less or none VOCs have been rapidly developed in research for future sustainable use. However, a few studies focusing on penetration and exposure condition of the substitute have been reported duo to the complexity and inaccessibility of painting industry. Surveys specifically looking at the present status of exposure condition were conducted to ascertain the popularization of water-based paints (WBPs) which concluded that markers of SBPs were detected in all 134 samples indicating bad industrial penetration...
June 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28622035/being-authentic-on-facebook-has-same-health-benefits-as-in-person-authentic-behavior
#11
Brenda K Wiederhold
No abstract text is available yet for this article.
June 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28621556/exposure-to-sexual-stimuli-induces-greater-discounting-leading-to-increased-involvement-in-cyber-delinquency-among-men
#12
Wen Cheng, Wen-Bin Chiou
People frequently encounter sexual stimuli during Internet use. Research has shown that stimuli inducing sexual motivation can lead to greater impulsivity in men, as manifested in greater temporal discounting (i.e., a tendency to prefer smaller, immediate gains to larger, future ones). Extant findings in crime research suggest that delinquents tend to focus on short-term gains while failing to adequately think through the longer-term consequences of delinquent behavior. We experimentally tested the possibility that exposure to sexual stimuli is associated with the tendency to engage in cyber delinquency among men, as a result of their overly discounting remote consequences...
June 16, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28621398/ab-initio-prediction-of-stable-confomeric-polymorphs-of-benzocaine-molecule-a-local-anaesthatic-molecule
#13
Pallipurath Nidhin, David Stephen, Selvaraj Arun Paul
An ab initio methodology to predict the crystal structures of thermodynamically stable polymorphs of benzocaine within the least energy region of energy landscape by analyzing the local minima from the initial gas phase optimization initiated through the flexible torsion using MP2/6-31G(d,p) method. The global search for the hypothetical dense packing for the structures within the energy penalty region of the local minima have revealed the possible stable conformers under a repulsion alone potential field. The generated hypothetical dense packings from the global search were selected for lattice minimization using the repulsion - dispersion potential field to authenticate the stability...
June 2017: Acta Chimica Slovenica
https://www.readbyqxmd.com/read/28620966/the-embodied-nurse-interdisciplinary-knowledge-exchange-between-compassionate-nursing-and-recent-developments-in-embodied-leadership-studies
#14
Kushwanth Koya, Jane Anderson, Petia Sice
AIM: To report a potential knowledge exchange between nursing studies and the results obtained from a study conducted into the attributes of embodied leadership. BACKGROUND: Leadership theories have been applied to evaluate, improve and train nursing practitioners in several previous studies. However, leadership research has entered a new phase where the focus is to produce sustainable leaders through authenticity and compassion, the same two characteristics identified as being of most success in emergent nursing practice...
June 16, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28620585/identification-of-a-large-family-of-slam-dependent-surface-lipoproteins-in-gram-negative-bacteria
#15
Yogesh Hooda, Christine C L Lai, Trevor F Moraes
The surfaces of many Gram-negative bacteria are decorated with soluble proteins anchored to the outer membrane via an acylated N-terminus; these proteins are referred to as surface lipoproteins or SLPs. In Neisseria meningitidis, SLPs such as transferrin-binding protein B (TbpB) and factor-H binding protein (fHbp) are essential for host colonization and infection because of their essential roles in iron acquisition and immune evasion, respectively. Recently, we identified a family of outer membrane proteins called Slam (Surface lipoprotein assembly modulator) that are essential for surface display of neisserial SLPs...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28620408/quality-control-of-the-traditional-patent-medicine-yimu-wan-based-on-smrt-sequencing-and-dna-barcoding
#16
Jing Jia, Zhichao Xu, Tianyi Xin, Linchun Shi, Jingyuan Song
Substandard traditional patent medicines may lead to global safety-related issues. Protecting consumers from the health risks associated with the integrity and authenticity of herbal preparations is of great concern. Of particular concern is quality control for traditional patent medicines. Here, we establish an effective approach for verifying the biological composition of traditional patent medicines based on single-molecule real-time (SMRT) sequencing and DNA barcoding. Yimu Wan (YMW), a classical herbal prescription recorded in the Chinese Pharmacopoeia, was chosen to test the method...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28619700/integrated-detection-and-prediction-of-influenza-activity-for-real-time-surveillance-algorithm-design
#17
Armin Spreco, Olle Eriksson, Örjan Dahlström, Benjamin John Cowling, Toomas Timpka
BACKGROUND: Influenza is a viral respiratory disease capable of causing epidemics that represent a threat to communities worldwide. The rapidly growing availability of electronic "big data" from diagnostic and prediagnostic sources in health care and public health settings permits advance of a new generation of methods for local detection and prediction of winter influenza seasons and influenza pandemics. OBJECTIVE: The aim of this study was to present a method for integrated detection and prediction of influenza virus activity in local settings using electronically available surveillance data and to evaluate its performance by retrospective application on authentic data from a Swedish county...
June 15, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28618131/pharmacognosy-phytochemistry-and-pharmacological-properties-of-achillea-millefolium-l-a-review
#18
REVIEW
Sofi Imtiyaz Ali, B Gopalakrishnan, V Venkatesalu
Achillea millefoilum L. (Yarrow) is an important species of Asteraceae family with common utilization in traditional medicine of several cultures from Europe to Asia for the treatment of spasmodic gastrointestinal disorders, hepatobiliary, gynecological disorders, against inflammation and for wound healing. An extensive review of literature was made on A. millefoilum L. using ethno botanical text books, published articles in peer-reviewed journals, unpublished materials and scientific databases. The Plant List, International Plant Name Index and Kew Botanical Garden databases were used to authenticate the scientific names...
June 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28618087/telephone-nursing-in-sweden-a-narrative-literature-review
#19
REVIEW
Elenor Kaminsky, Marta Röing, Annica Björkman, Inger K Holmström
Telephone nursing services are expanding globally. Swedish Healthcare Direct is the largest healthcare provider in Sweden. This paper provides a comprehensive understanding of telephone nursing, as reflected by research on Swedish national telephone nursing, and discusses the findings in relation to international literature. A descriptive, mixed-studies literature review was conducted. Twenty-four articles from January 2003 to April 2015 were identified from PubMed, Scopus, and CINAHL, and included. The issues explored in this study are how telephone nursing is perceived by callers, telephone nurses, and managers, and what characterizes such calls...
June 15, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28617288/fate-of-selected-pharmaceutically-active-compounds-in-the-integrated-fixed-film-activated-sludge-process
#20
K J Murray, W J Parker, L M Bragg, M R Servos
The potential for integrated fixed film activated sludge (IFAS) processes to achieve enhanced transformation of pharmaceuticals relative to conventional activated sludge (CAS) processes was assessed. Previous studies have focused on direct comparisons of parallel reactors with and without fixed film carriers and little information is available on the impacts of how varying operating parameters impact the differences in observed pharmaceutical compound (PC) transformation capabilities between CAS reactors and those equipped with both an activated sludge (AS) and fixed film carriers...
June 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
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