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Sandeep vijay

Benjamin Laliberte, Brent N Reed, Sandeep Devabhakthuni, Kristin Watson, Vijay Ivaturi, Tao Liu, Stephen S Gottlieb
BACKGROUND: Heart failure (HF) is associated with high 30-day readmission rates and places significant financial burden on the health care system. The aim of this study was to determine if the duration of observation on an oral loop diuretic before discharge is associated with a reduction in 30-day HF readmission in patients with acute decompensated HF (ADHF). METHODS AND RESULTS: This was a retrospective study of adult patients admitted for ADHF at a large academic medical center...
July 5, 2017: Journal of Cardiac Failure
Sandeep Chakane, Vijay Markad, Kisan Kodam, Leif Bülow
Hemoglobin (Hb) is a potent oxidant outside the erythrocyte. The tyrosines α140 and β145 play an important role in the structure and function of Hb by forming switch and hinge contacts. These carboxy-terminal residues of the alpha and beta chains, respectively, were replaced to phenylalanine and several different methods were used to characterize the obtained mutants including a comet and plasmid DNA cleavage assay. It was observed that the genotoxic effect was 40% higher for αY140F compared with the wildtype, the βY145F and the double (αY140/β145F) mutants as determined by the comet assay...
2017: Advances in Experimental Medicine and Biology
Santanu Guha, Rishi Sethi, Saumitra Ray, Vinay K Bahl, S Shanmugasundaram, Prafula Kerkar, Sivasubramanian Ramakrishnan, Rakesh Yadav, Gaurav Chaudhary, Aditya Kapoor, Ajay Mahajan, Ajay Kumar Sinha, Ajit Mullasari, Akshyaya Pradhan, Amal Kumar Banerjee, B P Singh, J Balachander, Brian Pinto, C N Manjunath, Chandrashekhar Makhale, Debabrata Roy, Dhiman Kahali, Geevar Zachariah, G S Wander, H C Kalita, H K Chopra, A Jabir, JagMohan Tharakan, Justin Paul, K Venogopal, K B Baksi, Kajal Ganguly, Kewal C Goswami, M Somasundaram, M K Chhetri, M S Hiremath, M S Ravi, Mrinal Kanti Das, N N Khanna, P B Jayagopal, P K Asokan, P K Deb, P P Mohanan, Praveen Chandra, Col R Girish, O Rabindra Nath, Rakesh Gupta, C Raghu, Sameer Dani, Sandeep Bansal, Sanjay Tyagi, Satyanarayan Routray, Satyendra Tewari, Sarat Chandra, Shishu Shankar Mishra, Sibananda Datta, S S Chaterjee, Soumitra Kumar, Soura Mookerjee, Suma M Victor, Sundeep Mishra, Thomas Alexander, Umesh Chandra Samal, Vijay Trehan
No abstract text is available yet for this article.
April 2017: Indian Heart Journal
Sandeep Singh Sidhu, Nirmaljeet Singh Malhi, Omesh Goyal, Rupinder Singh, Usha Dutta, Rajiv Grover, J S Sidhu, Vijay Nanda, Harmeet Saluja, Ajesh Bansal, Gursewak Singh, Alok Sehgal, Harsh Kishore, Simran Sidhu
BACKGROUND AND AIMS: Recently, Sofosbuvir was launched in India at affordable cost. We conducted a real-life study to determine the efficacy and safety of Sofosbuvir plus Ribavirin, with and without peginterferon-alfa 2a, in patients with chronic hepatitis C (CHC) genotype 3, the commonest genotype in South Asia. METHODS: This study included data of CHC patients from 11 sites in northern India between March 2015 and December 2015 (n = 1203). Patients with CHC genotype 3 (n = 931), who were treated with either Sofosbuvir 400 mg plus weight-based Ribavirin, daily ×24 weeks (n = 432) (dual therapy), or Peginterferon-α2a 180 mcg weekly, Sofosbuvir 400 mg plus weight-based Ribavirin, daily ×12 weeks (n = 499) (triple therapy) were included for analysis...
May 2017: Hepatology International
Vijay Kamath, Anthony L Rios, Nitin Mishra, Sandeep A Sathyanarayana, Kambhampaty V Krishnasastry, Eugene Rubach
Aneurysmal degeneration of the visceral branches of the abdominal aorta is a rare and potentially life-threatening disease entity. Visceral artery aneurysms (VAAs) are exceedingly rare and have a prevalence of 0.1 to 2%. The left gastric artery aneurysm (LGAA) is even more rare and accounts for less than 4% of all VAAs. There is scarce literature on treatment of LGAA by embolization; however, to date successful laparoscopic repair of an LGAA has not been described. We describe the successful treatment of an LGAA by laparoscopic ligation and resection in a 68-year-old male patient...
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
Kelika Prakash, Anshuman Singh, Sandeep Sharma, Vijay Kant Pandey
No abstract text is available yet for this article.
October 2016: Saudi Journal of Anaesthesia
Sheetu Singh, Bridget F Collins, Bharat B Sharma, Jyotsna M Joshi, Deepak Talwar, Sandeep Katiyar, Nishtha Singh, Lawrence Ho, Jai Kumar Samaria, Parthasarathi Bhattacharya, Rakesh Gupta, Sudhir Chaudhari, Tejraj Singh, Vijay Moond, Sudhakar Pipavath, Jitesh Ahuja, Ravindran Chetambath, Aloke G Ghoshal, Nirmal K Jain, H J Gayathri Devi, Surya Kant, Parvaiz Koul, Raja Dhar, Rajesh Swarnakar, Surendra K Sharma, Dhrubajyoti J Roy, Kripesh R Sarmah, Bhavin Jankharia, Rodney Schmidt, Santosh K Katiyar, Arpita Jindal, Daya K Mangal, Virendra Singh, Ganesh Raghu
RATIONALE: Interstitial lung disease (ILD) is a heterogeneous group of acute and chronic inflammatory and fibrotic lung diseases. Existing ILD registries have had variable findings. Little is known about the clinical profile of ILDs in India. OBJECTIVES: To characterize new-onset ILDs in India by creating a prospective ILD using multidisciplinary discussion (MDD) to validate diagnoses. METHODS: Adult patients of Indian origin living in India with new-onset ILD (27 centers, 19 Indian cities, March 2012-June 2015) without malignancy or infection were included...
March 15, 2017: American Journal of Respiratory and Critical Care Medicine
Gautam Sharma, R Anantha Krishnan, Vijay Bohra, Sivasubramanian Ramakrishnan, Nitish Naik, Sandeep Seth, Rajnish Juneja, M Kalaivani, Vinay Kumar Bahl
BACKGROUND: Patients with rheumatic mitral stenosis (MS) and atrial fibrillation (AF) are at risk for thromboembolism and restoration of sinus rhythm (SR) may be the preferred strategy. Percutaneous balloon mitral valvotomy (PBMV) improves hemodynamics, but may not be enough to restore SR. METHODS: Prospective randomized study aimed at evaluating efficacy of early direct current cardioversion (DCCV) following successful PBMV in patients with long-standing AF. Group 1 (n=20) had patients of rheumatic MS with AF who underwent successful PBMV...
July 2016: Indian Heart Journal
Christine E Shulenberger, Anthony Jiang, Sandeep Devabhakthuni, Vijay Ivaturi, Tao Liu, Brent N Reed
STUDY OBJECTIVE: To assess the efficacy and safety of intravenous (IV) chlorothiazide versus oral metolazone when added to loop diuretics in patients with acute decompensated heart failure (ADHF) and loop diuretic resistance. DESIGN: Retrospective cohort study. SETTING: Large urban academic medical center. PATIENTS: Adults admitted with ADHF between 2005 and 2015 who had loop diuretic resistance, defined as administration of IV furosemide at a dose of 160 mg/day or higher (or an equivalent dose of IV bumetanide), during hospitalization, and who then received at least one dose of IV chlorothiazide (88 patients) or oral metolazone (89 patients) to augment diuresis...
August 2016: Pharmacotherapy
Sandeep Grover, K Suchendra, Aseem Mehra, Vijay Parkash, Vikas Saini, Shiv Bagga
There is limited literature on the use of electroconvulsive therapy (ECT) in patients with recent myocardial infarction and in those with reduced cardiac output. In this report, we describe the safe use of ECT in a 70-year-male suffering from severe depressive episode with psychotic symptoms. He had a history of poor response to adequate pharmacotherapy and had suffered from myocardial infraction (MI), about 3 weeks prior to admission to the psychiatric unit. In view of severe depression associated with marked anxiety, agitation, psychotic symptoms, and poor food intake he was started on ECT after 5 weeks of MI when his cardiac output was only 30%...
July 2015: Industrial Psychiatry Journal
Roumina Hasan, Vidya Monappa, Sandeep Kumar, Vijay Kumar
Amongst the varied, diverse causes of intraabdominal masses in infancy and early childhood, gastric teratomas (GTs) account for a very small proportion. A worldwide literature search reveals only around one hundred cases of GT and also supports the fact that its preoperative diagnosis remains elusive. Here we report the case of a two-month-old male who presented to the pediatric surgery outpatient department of Kasturba Medical College and Hospital, Karnataka, India, with progressive distension of abdomen since birth...
May 2016: Oman Medical Journal
Neha Kawatra Madan, Karan Madan, Deepali Jain, Ritika Walia, Anant Mohan, Vijay Hadda, Sandeep Mathur, Venkateswaran K Iyer, Gopi C Khilnani, Randeep Guleria
BACKGROUND: Conventional transbronchial needle aspiration (c-TBNA) is an underutilized bronchoscopic modality. Endobronchial ultrasound (EBUS) guided-TBNA though efficacious is an expensive modality, facilities of which are available at only limited centers. c-TBNA is cost-effective and has potential for wide utilization especially in resource-limited settings. Rapid on-site evaluation (ROSE) improves the yield of c-TBNA. MATERIALS AND METHODS: A retrospective review of the bronchoscopy records (May 2012 to July 2014) was performed...
January 2016: Journal of Cytology
Rohit Bhatia, Vijay Kataria, Deepti Vibha, Aanchal Kakkar, Kameshwar Prasad, Sandeep Mathur, Ajay Garg, Sameer Bakhshi
No abstract text is available yet for this article.
February 23, 2016: Neurology
Valasingam Sandeep, Manikya Kumar, P Jyostna, Vijay Duggi
Effective pain control during local anesthetic injection is the cornerstone of behavior guidance in pediatric dentistry. The aim of this study was to evaluate the practical efficacy of a 2-stage injection technique in reducing injection pain in children. This was a split-mouth, randomized controlled crossover trial. One hundred cooperative children aged 7 to 13 years in need of bilateral local anesthetic injections (inferior alveolar nerve block, posterior superior alveolar nerve block, or maxillary and mandibular buccal infiltrations) for restorative, endodontic, and extraction treatments were recruited for the study...
2016: Anesthesia Progress
Sandeep Choudhary, Ashay Jain, Mohd Cairul Iqbal Mohd Amin, Vijay Mishra, Govind P Agrawal, Prashant Kesharwani
The study was intended to develop a new intra-gastric floating in situ microballoons system for controlled delivery of rabeprazole sodium and amoxicillin trihydrate for the treatment of peptic ulcer disease. Eudragit S-100 and hydroxypropyl methyl cellulose based low density microballoons systems were fabricated by employing varying concentrations of Eudragit S-100 and hydroxypropyl methyl cellulose, to which varying concentrations of drug was added, and formulated by stirring at various speed and time to optimize the process and formulation variable...
May 1, 2016: Colloids and Surfaces. B, Biointerfaces
Senthilnathan Palanisamy, Nikunj D Patel, Sandeep C Sabnis, Nalankilli Palanisamy, Anand Vijay, Palanivelu Chinnusamy
Persistent Mullerian duct syndrome (PMDS) is one of the three rare intersex disorders caused by defective anti-mullerian hormone or its receptor, characterized by undescended testes with presence of underdeveloped derivatives of mullerian duct in genetically male infant or adult with normal external genitals and virilization. This population will essentially have normal, 46(XY), phenotype. We hereby present a case of PMDS, presented with incarcerated left inguinal hernia associated with cryptorchidism and seminoma of right testes...
October 2015: Journal of Minimal Access Surgery
Kumud Saklani, Sandeep Singh, Vijay K Purohit, P Prasad, A R Nautiyal
The species Elaeocarpus sphaericus (Rudraksha) is a religious, medicinally important threatened tree of India. An efficient micropropagation protocol has been developed from nodal explants of this plant species collected from north-east India for large scale production of planting material at favourable sites within the country. Best shoot initiation occurred in MS medium supplemented with 2.2μM BA+2.2μM Kn in combination. Addition of Casein Hydrolysate (CH) (100mg/L) increased the shoot number. Microshoots excised and subcultured in 2...
October 2015: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
Vijay Soni, Sandeep Upadhayay, Priyanka Suryadevara, Ganesh Samla, Archana Singh, Perumal Yogeeswari, Dharmarajan Sriram, Vinay Kumar Nandicoori
M. tuberculosis N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmUMtb) is a bi-functional enzyme engaged in the synthesis of two metabolic intermediates N-acetylglucosamine-1-phosphate (GlcNAc-1-P) and UDP-GlcNAc, catalyzed by the C- and N-terminal domains respectively. UDP-GlcNAc is a key metabolite essential for the synthesis of peptidoglycan, disaccharide linker, arabinogalactan and mycothiols. While glmUMtb was predicted to be an essential gene, till date the role of GlmUMtb in modulating the in vitro growth of Mtb or its role in survival of pathogen ex vivo / in vivo have not been deciphered...
October 2015: PLoS Pathogens
Bharti Mehta, Vijay Kumar, Sumit Chawla, Sandeep Sachdeva, Debjyoti Mahopatra
BACKGROUND: Hypertensive disorders during pregnancy occur in women with preexisting primary or secondary chronic hypertension, and in women who develop new-onset hypertension in the second half of pregnancy. The present study was undertaken to study the prevalence and correlates of hypertension in pregnancy in a rural block of Haryana. MATERIALS AND METHODS: This cross-sectional study was carried out in the all 20 subcenters under Community Health Center (CHC) Chiri, Block Lakhanmajra...
October 2015: Indian Journal of Community Medicine
Senthilnathan Palanisamy, Nikunj Patel, Sandeep Sabnis, Nalankilli Palanisamy, Anand Vijay, Praveenraj Palanivelu, R Parthasarthi, Palanivelu Chinnusamy
BACKGROUND: Gall bladder cancer (GBC) is the most common and aggressive malignancy of the biliary tract with extremely poor prognosis. Radical resection remains the only potential curative treatment for operable lesions. Although laparoscopic approach is now considered as standard of care for many gastrointestinal malignancies, surgical community is still reluctant to use this approach for GBC probably because of fear of tumor dissemination, inadequate lymphadenectomy and overall nihilistic approach...
June 2016: Surgical Endoscopy
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