Read by QxMD icon Read

Contact lenses

Frank L Schwartz, Cynthia R Marling, Razvan C Bunescu
Development of truly useful wearable physiologic monitoring devices for use in diabetes management is still in its infancy. From wearable activity monitors such as fitness trackers and smart watches to contact lenses measuring glucose levels in tears, we are just at the threshold of their coming use in medicine. Ultimately, such devices could help to improve the performance of sense-and-respond insulin pumps, illuminate the impact of physical activity on blood glucose levels, and improve patient safety. This is a summary of our experience attempting to use such devices to enhance continuous glucose monitoring-augmented insulin pump therapy...
March 1, 2018: Journal of Diabetes Science and Technology
Muhammed Veli, Aydogan Ozcan
We present a cost-effective and portable platform based on contact lenses for non-invasively detecting Staphylococcus aureus, which is part of the human ocular microbiome and resides on the cornea and conjunctiva. Using Staphylococcus aureus-specific antibodies and a surface chemistry protocol that is compatible with human tear, contact lenses are designed to specifically capture Staphylococcus aureus. After the bacteria capture on the lens, and right before its imaging, the captured bacteria are tagged with surface-functionalized polystyrene microparticles...
March 9, 2018: ACS Nano
Nan Jiang, Yunuen Montelongo, Haider Butt, Ali K Yetisen
Contact lens is a ubiquitous technology used for vision correction and cosmetics. Sensing in contact lenses has emerged as a potential platform for minimally invasive point-of-care diagnostics. Here, a microlithography method is developed to fabricate microconcavities and microchannels in a hydrogel-based contact lens via a combination of laser patterning and embedded templating. Optical microlithography parameters influencing the formation of microconcavities including ablation power (4.3 W) and beam speed (50 mm s-1 ) are optimized to control the microconcavity depth (100 µm) and diameter (1...
March 9, 2018: Small
Yana Fu, Wuying Zhou, Wei Li, Xiaolei Lin, Qi Dai
RATIONALE: The incidence of cornea disorders after laser peripheral iridotomy (LPI) is extremely low. However, cornea Descemet membrane detachment (DMD) combined with corneal decompensation after LPI could still occur. PATIENT CONCERNS: A 69-year-old Chinese woman presented with persistent widespread corneal edema and inferior bullous lesions in her right eye for half a year. She had undergone LPI in both eyes 10 years ago for a prophylactic treatment. The patient received a detailed examination of vivo corneal confocal microscopy and sept-source optical coherence tomography (SS-OCT)...
March 2018: Medicine (Baltimore)
Cristina Nicula, Izabela Szabo, Ozana Ivan
The article presents the modern treatment with stem cells in the reconstruction of ocular surface. The turnover of the stem cells, the location in the limbus areas, the importance of limbal stem cells presence, the clinical appearance of stem cell deficiency, investigations method for this illness and the management of stem cell deficiency (artificial lacrimal tear drops, mini scleral contact lenses and the surgical treatment with allografts and autografts of stem cells) were taken into account.
October 2017: Romanian Journal of Ophthalmology
AnnMarie Hipsley, Brad Hall, Karolinne M Rocha
Presbyopia corrections traditionally have been approached with attempts to exchange power, either at the cornea or the lens planes, inducing multifocality, or altering asphericity to impact the optical system. Treatments that affect the visual axis, such as spectacle and contact lens correction, refractive surgeries, corneal onlays and inlays, and intraocular lenses are typically unable to restore true accommodation to the presbyopic eye. Their aim is instead to enhance 'pseudoaccommodation' by facilitating an extended depth-of-focus for which vision is sufficient...
2018: Eye and Vision (London, England)
Motohiro Itoi, Motozumi Itoi, Nathan Efron, Philip Morgan, Craig Woods
PURPOSE: To review contact lens prescribing trends in Japan between 2003 and 2016. METHODS: An annual survey of contact lens prescribing trends was conducted each year between 2003 and 2016. Japanese ophthalmologists were asked to provide information relating to ten consecutive contact lens fittings between January and March every year. RESULTS: Over the 14 years of the annual survey, data from a total of 64,122 contact lens fits were returned by ophthalmologists...
February 26, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Daddi Fadel
PURPOSE: To summarize the research findings on the ocular surface profile, to provide a definition and a classification of the corneoscleral shape, and to offer guidelines in selecting scleral lens design. METHODS: The definition of rotational symmetry and rotational asymmetry was inquired and PubMed searches were conducted. RESULTS: The better understanding of the scleral contact lens comportment on the eye and the introduction of new diagnostic instruments to measure the anterior ocular surface have led to improve comprehension of corneoscleral contour formulating new scleral lens designs...
February 26, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Pauline Kang
Recent increases in global myopia prevalence rates have raised significant concerns as myopia increases the lifelong risk of various sight-threatening ocular conditions. This growing public health burden has generated significant research interests into understanding both its aetiology and developing effective methods to slow down or stop its development, methods collectively termed 'myopia control'. The growing body of research has demonstrated benefits of various optical and pharmacological treatments resulting in myopia control management increasingly becoming a part of main stream clinical practice...
February 28, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Dan-Na Shi, Hang Song, Tong Ding, Wei-Qiang Qiu, Wei Wang
AIM: To evaluate the safety of therapeutic bandage contact lens for post-cataract surgery patients and to illustrate its efficacy on post-operative comfort and tear-film stability. METHODS: A total of 40 participants were recruited and randomly divided into two groups. Group one was instructed to wear bandage contact lenses for a week and use antibiotic eye drops for a month since the first day after surgery. Group two received sub-conjunctival injection of tobramycin and was asked to wear eye pads on the first day after surgery and then were instructed to use antibiotic eye drops as the first group did...
2018: International Journal of Ophthalmology
Rafał Brygoła, Sławomir Sęk, Maciej Sokołowski, Marek Kowalczyk-Hernández, Jacek Pniewski
In the paper the results of AFM surface profile measurements of seven new long-wear contact lenses (CL) available in Poland are presented. Calculated statistical roughness parameters are shown, namely standard deviation (RMS), mean roughness, maximum difference between peak and valley, skewness, and kurtosis. It is demonstrated that CLs manufactured using recent methods, such as two-stage polimerisation or extending silicon chains exhibit small RMS, less than 10 nm, in comparison with older generation CLs which maintains RMS on the level of tens of nanometers...
February 15, 2018: Colloids and Surfaces. B, Biointerfaces
Waleed Ali Abou Samra, Amani E Badawi, Hanem Kishk, Ayman Abd El Ghafar, Mohamed M Elwan, Hossam Youssef Abouelkheir
Objectives: To study the fitting and the visual rehabilitation obtained with a corneoscleral contact lens, namely, Rose K2 XL in patients with irregular cornea. Methods: This prospective study included 36 eyes of 36 patients with irregular cornea fitted with Rose K2 XL. Refractive and visual outcomes and mesopic and aberrometric parameters of fitted eyes were assessed at 2 weeks, 3 months, and 6 months after the initial lens use. Objective and subjective parameters of patient satisfaction and lens comfort were noted...
2018: Journal of Ophthalmology
Leonid L Doskolovich, Evgeni A Bezus, Andrey A Morozov, Vladimir Osipov, James S Wolffsohn, Boris Chichkov
We propose a method for designing multifocal diffractive lenses generating prescribed sets of foci with fixed positions at several different wavelengths. The method is based on minimizing the difference between the complex amplitudes of the beams generated by the lens microrelief at the design wavelengths, and the functions of the complex transmission of multifocal lenses calculated for these wavelengths. As an example, a zone plate generating three fixed foci at three different wavelengths was designed, fabricated, and experimentally investigated...
February 19, 2018: Optics Express
Erika Orosz, Nóra Szentmáry, Huba J Kiss, Ágnes Farkas, István Kucsera, Zoltán Zsolt Nagy
Acanthamoeba has a worldwide distribution in the environment and it is capable of causing a painful sight-threatening disease of the cornea designated as Acanthamoeba keratitis (AK). Nowadays, the cases of AK have surged all over the world along with its disease burden due to increasing use of contact lenses used not only for optical correction but also for cosmetic purposes. In our present work, epithelial abrasion of a 27-year-old female soft contact lens wearer with keratitis was examined. Genotype identification was carried out with a real-time fluorescence resonance energy transfer polymerase chain reaction (PCR) assay based on sequence analysis of the 18S rRNA gene...
February 23, 2018: Acta Microbiologica et Immunologica Hungarica
Varshini Varadaraj, Malik Y Kahook, Pradeep Y Ramulu, Ian F Pitha
PURPOSE: To assess patient acceptance of different methods for delivering sustained-release, intraocular pressure (IOP) lowering medications METHODS:: Electronic surveys were administered to 150 patients at two glaucoma clinics. Participants were questioned on their willingness to accept: (1) drug-eluting contact lenses, (2) ring inserts (3) punctal plugs, and (4) sub-conjunctival injections as alternatives to IOP-lowering eye drops based on various success levels. Multivariable logistic regression models determined the association between device type and treatment acceptance adjusting for age, gender, study site, cost burden of drops, and previous contact lens use...
February 16, 2018: Journal of Glaucoma
Ana Topete, Andreia S Oliveira, A Fernandes, T G Nunes, A P Serro, B Saramago
Although the possibility of using drug-loaded ophthalmic lens to promote sustained drug release has been thoroughly pursued, there are still problems to be solved associated to the different alternatives. In this work, we went back to the traditional method of drug loading by soaking in the drug solution and tried to optimize the release profiles by changing the temperature and the time of loading. Two materials commercially available under the names of CI26Y and Definitive 50 were chosen. CI26Y is used for intraocular lenses (IOLs) and Definitive 50 for soft contact lenses (SCLs)...
February 14, 2018: European Journal of Pharmaceutical Sciences
Ameen Hadi Mohammed, Mansor B Ahmad, Nor Azowa Ibrahim, Norhazlin Zainuddin
BACKGROUND: The incorporation of two different monomers, having different properties, in the same polymer molecule leads to the formation of new materials with great scientific and commercial importance. The basic requirements for polymeric materials in some areas of biomedical applications are that they are hydrophilic, having good mechanical and thermal properties, soft, and oxygen-permeable. RESULTS: A series of 3-(trimethoxysilyl) propyl methacrylate/N-vinyl pyrrolidone (TMSPM/NVP) xerogels containing different concentration of ethylene glycol dimethacrylate (EGDMA) as crosslinking agent were prepared by bulk polymerization to high conversion using BPO as initiator...
February 13, 2018: Chemistry Central Journal
Mehrdad Mohammadpour, Zahra Heidari, Hassan Hashemi, Soheila Asgari
OBJECTIVES: To compare the lotrafilcon B and comfilcon A silicone hydrogel bandage contact lenses after photorefractive keratectomy (PRK). METHODS: One hundred twenty eyes of 60 patients who underwent PRK were included in this randomized clinical trial study. In the end of the surgery, the lotrafilcon B (Air Optix; Ciba Vision, Duluth, GA) was used in one eye and the comfilcon A (Biofinity; Coopervision, Fairport, NY) was used in the fellow eye randomly. Pain and discomfort were assessed on the first and third day after surgery by visual analogue scale...
February 12, 2018: Eye & Contact Lens
Alicia Ruiz-Pomeda, Belén Pérez-Sánchez, Francisco L Prieto-Garrido, Ramón Gutiérrez-Ortega, César Villa-Collar
OBJECTIVES: To assess the relative clinical success of MiSight contact lenses (CLs) (study group) and distance single-vision (SV) spectacles (control group) in children in terms of adverse events (AEs), discontinuations, and tear film osmolarity over a 2-year period. METHODS: Seventy-four subjects aged 8 to 12 with myopia of -0.75 to -4.00 D and astigmatism less than 1.00 D were randomly assigned to MiSight CLs or SV groups. Subjects were monitored at 6-month intervals over the course of 24 months and advised to report to the clinic immediately should AEs occur...
February 12, 2018: Eye & Contact Lens
Orapan Manajit, Siwaporn Longyant, Paisarn Sithigorngul, Parin Chaivisuthangkura
Pseudomonas aeruginosa (P. aeruginosa) is an important opportunistic pathogen that causes serious infections in humans, including keratitis in contact lens wearers. Therefore, establishing a rapid, specific and sensitive method for the identification of P. aeruginosa is imperative. In the present study, the uracil-DNA-glycosylase-supplemented loop-mediated isothermal amplification combined with nanogold labeled hybridization probe (UDG-LAMP-AuNP) was developed for the detection of P. aeruginosa. UDG-LAMP was performed to prevent carry over contamination and the LAMP reactions can be readily observed using the nanogold probe...
February 2, 2018: Molecular Medicine Reports
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"