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https://www.readbyqxmd.com/read/28439978/simulation-of-commercial-vs-theoretically-optimised-contact-lenses-for-presbyopia
#1
Richard Legras, David Rio
PURPOSE: To compare theoretically optimised bifocal contact lens optical designs to commercially available optical designs for presbyopia. METHODS: Retinal images were simulated, using a numerical eye model, from -6 (i.e., near vision) to +2 D for each 0.25 D. Ten optical profiles were simulated. Four of them corresponded to commercial contact lenses (i.e., Acuvue Oasys for Presbyopia®, Air Optix Aqua Multifocal®, Purevision Multifocal® and Distance Biofinity Multifocal®)...
May 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28426715/acute-hypoxia-influences-collagen-and-matrix-metalloproteinase-expression-by-human-keratoconus-cells-in-vitro
#2
Tina B McKay, Jesper Hjortdal, Shrestha Priyadarsini, Dimitrios Karamichos
Keratoconus (KC) is a progressive corneal ectasia linked to thinning of the central cornea. Hard contact lenses, rigid gas permeable lenses, and scleral lenses are the primary treatment modalities for early to mid- stages of KC to correct refractive error and astigmatism that develops as a result of an irregular corneal structure. These treatments are associated with significant drawbacks, including reduced availability of the tear film and oxygen to the corneal epithelium and stroma. However, it remains unknown whether hypoxia affects corneal integrity in the KC pathobiology...
2017: PloS One
https://www.readbyqxmd.com/read/28421562/prevention-of-bacterial-biofilm-formation-on-soft-contact-lenses-using-natural-compounds
#3
Amira M El-Ganiny, Ghada H Shaker, Abeer A Aboelazm, Heba A El-Dash
PURPOSE: In eye care field, contact lenses (CL) have a great impact on improving vision, but their use can be limited by ocular infection. CL- associated infections can be reduced by good attention to CL storage case practice. CL-care solutions should be able to control microbial growth on CL. The aim of the study was to evaluate and compare the efficacy of CL-care solutions (found in Egyptian market) with some natural compounds in removal and inhibition of bacterial biofilm formed on soft CL...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28419129/factors-related-to-axial-length-elongation-and-myopia-progression-in-orthokeratology-practice
#4
Bingjie Wang, Rajeev K Naidu, Xiaomei Qu
PURPOSE: To investigate which baseline factors are predictive for axial length growth over an average period of 2.5 years in a group of children wearing orthokeratology (OK) contact lenses. METHODS: In this retrospective study, the clinical records of 249 new OK wearers between January 2012 and December 2013 from the contact lens clinic at the Eye and ENT Hospital of Fudan University were reviewed. The primary outcome measure was axial length change from baseline to the time of review (July-August 2015)...
2017: PloS One
https://www.readbyqxmd.com/read/28415418/uv-assisted-treatment-on-hydrophobic-acrylic-iols-anterior-surface-with-methacryloyloxyethyl-phosphorylcholine-reducing-inflammation-and-maintaining-low-posterior-capsular-opacification-properties
#5
Xiaodan Huang, Chenqi Luo, Lin Lin, Li Zhang, Heyi Li, Ke Yao, Zhikang Xu
In order to enhance the surface biocompatibility of hydrophobic acrylic intraocular lenses (IOLs), the anterior surface was modified through graft polymerization with methacryloyloxyethyl phosphorylcholine (MPC) initiated by ultraviolet radiation. Chemical changes on the IOL surface were characterised by X-ray photoelectron spectroscopy (XPS) to confirm the covalent binding of MPC. Field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) analysis were used to characterise the morphological changes to the IOL surface...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28412796/-multiple-issues-in-multifocal-intraocular-lens
#6
Z H Li, Z Ye, Y Huang
The occurrence of multifocal intraocular lens (MIOL) is known as an important period in the development of cataract surgery, which can provide a simultaneous vision without the use of spectacles or contact lenses. However, in the current stage, MIOL implantation may also lead to decreased visual acuity and increased risk of photic phenomena, thus in some instance a second procedure to exchange the MIOL is necessary. Optimizing visual outcomes of MIOL implantation and controlling adverse effects has become the focus for ophthalmologists...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28412447/improved-release-of-triamcinolone-acetonide-from-medicated-soft-contact-lenses-loaded-with-drug-nanosuspensions
#7
Eva García-Millán, Mónica Quintáns-Carballo, Francisco Javier Otero-Espinar
Drug nanosuspensions (NSs) show a significant potential to improve loading and release properties of the poorly water soluble drug triamcinolone acetonide (TA) from poly(hydroxyethyl methacrylate) (pHEMA) soft contact lenses. In this work, TA NSs were developed by a controlled precipitation method using a fractional factorial Plackett-Burmann design. Poloxamer 407 (PL) and polyvinyl alcohol (PVA) as stabilizing agents were selected. NSs were characterized in terms of their drug content, particle size and morphology...
April 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28410356/water-exposure-is-a-common-risk-behavior-among-soft-and-gas-permeable-contact-lens-wearers
#8
Aaron B Zimmerman, Kathryn Richdale, Gladys Lynn Mitchell, Beth T Kinoshita, Dawn Y Lam, Heidi Wagner, Luigina Sorbara, Robin L Chalmers, Sarah A Collier, Jennifer R Cope, Maya M Rao, Michael J Beach, Jonathan S Yoder
PURPOSE: To understand soft contact lens (SCL) and gas-permeable (GP) lens wearers' behaviors and knowledge regarding exposure of lenses to water. METHODS: The Contact Lens Risk Survey (CLRS) and health behavior questions were completed online by a convenience sample of 1056 SCL and 85 GP lens wearers aged 20 to 76 years. Participants were asked about exposing their lenses to water and their understanding of risks associated with these behaviors. Chi-square analyses examined relationships between patient behaviors and perceptions...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28410281/evaluated-conjunctival-blood-flow-velocity-in-daily-contact-lens-wearers
#9
Yingying Shi, Liang Hu, Wan Chen, Dongyi Qu, Hong Jiang, Jianhua Wang
OBJECTIVE: This study examined conjunctival microvasculature development in long-term habitual contact lens (HCL) wearers after a night of sleep. METHODS: Twenty HCL wearers (15 women and 5 men, aged 28.6±6.9 years, mean age±standard deviation) who had worn contact lenses on a daily basis for at least 3 years and 40 noncontact lens (NCL) wearers (23 women and 17 men, aged 36.5±6.6 years, mean age±standard deviation) participated in the study. A functional slitlamp biomicroscopy imaging system was used to image the temporal bulbar conjunctiva...
April 13, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28410280/long-term-impacts-of-orthokeratology-treatment-on-sub-basal-nerve-plexus-and-corneal-sensitivity-responses-and-their-reversibility
#10
María Nombela-Palomo, Gema Felipe-Marquez, Miguel Angel Teus, Jose Luis Hernandez-Verdejo, Amelia Nieto-Bona
PURPOSE: To examine the effects of one year of overnight orthokeratology (OK) treatment on the sub-basal nerve plexus (SBNP) and corneal sensitivity and to assess the reversibility of these effects one month after treatment interruption. METHODS: Thirty-two subjects with low-moderate myopia underwent OK treatment for one year. Fifteen non-contact lens wearers served as controls. At the time points baseline, one year of treatment, and one month after removing the OK lenses, two tests were conducted: corneal sensitivity (Cochet-Bonnet esthesiometer) and SBNP imaging by in vivo confocal microscopy...
April 13, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28404522/observations-on-the-relationship-between-anisometropia-amblyopia-and-strabismus
#11
Earl L Smith, Li-Fang Hung, Baskar Arumugam, Janice M Wensveen, Yuzo M Chino, Ronald S Harwerth
We investigated the potential causal relationships between anisometropia, amblyopia and strabismus, specifically to determine whether either amblyopia or strabismus interfered with emmetropization. We analyzed data from non-human primates that were relevant to the co-existence of anisometropia, amblyopia and strabismus in children. We relied on interocular comparisons of spatial vision and refractive development in animals reared with 1) monocular form deprivation; 2) anisometropia optically imposed by either contact lenses or spectacle lenses; 3) organic amblyopia produced by laser ablation of the fovea; and 4) strabismus that was either optically imposed with prisms or produced by either surgical or pharmacological manipulation of the extraocular muscles...
April 18, 2017: Vision Research
https://www.readbyqxmd.com/read/28397809/second-harmonic-generation-imaging-of-corneal-stroma-after-infection-by-pseudomonas-aeruginosa
#12
Danielle M Robertson, Nathan A Rogers, W Matthew Petroll, Meifang Zhu
Pseudomonas aeruginosa is a pathogenic gram-negative organism that has the ability to cause blinding corneal infections following trauma and during contact lens wear. In this study, we investigated the directional movement and orientation of an invasive corneal isolate of P. aeruginosa in the corneal stroma during infection of ex vivo and in vivo rabbit corneas using multiphoton fluorescence and second harmonic generation (SHG) imaging. Ex vivo, rabbit corneas were subject to three partial thickness wounds prior to inoculation...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28380096/visual-rehabilitation-using-mini-scleral-contact-lenses-after-penetrating-keratoplasty
#13
Guilherme Andrade do Nascimento Rocha, Patrícia Oliveira Braga Miziara, Ana Clara Vieira de Castro, Arthur Andrade do Nascimento Rocha
Purpose: To report the visual rehabilitation outcomes and complications of patients fitted with mini-scleral rigid gas-permeable (RGP) contact lenses (mini-SCLs) after penetrating keratoplasty. Methods: We retrospectively reviewed 27 eyes (21 patients) that were fitted with mini-SCLs between October 2013 and December 2014. We analyzed demographic data, previous corneal disorders, visual outcomes, interval from keratoplasty to contact lens fitting, topographic and specular microscope data, fitted contact lens parameters, and complications...
January 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28370795/a-pair-of-glasses-and-beyond-impact-of-refractive-error-on-people-s-well-being
#14
Himal Kandel, Jyoti Khadka, Michael Goggin, Konrad Pesudovs
IMPORTANCE: This study qualitative explores the impact of refractive error on adults, particularly after correction. BACKGROUND: The study aimed to explore the impact of refractive error on people's quality of life. DESIGN: Cross sectional; In-depth telephone and face-to-face semi-structured interviews; Qualitative study with inductive and deductive processes PARTICIPANTS: 48 adults with refractive error (including presbyopia) were recruited from the Flinders Vision, the Ashford Advanced Eye Care and among Flinders University staff and students, in South Australia...
March 31, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28368993/penetrating-keratoplasty-at-a-tertiary-referral-center-in-ethiopia-indications-and-outcomes
#15
Menen Ayalew, Yonas Tilahun, Doug Holsclaw, Maanasa Indaram, Nicole E Stoller, Jeremy D Keenan, Jennifer Rose-Nussbaumer
PURPOSE: To describe the indications, visual acuity outcomes, and graft survival after penetrating keratoplasty (PKP) in Addis Ababa, Ethiopia. METHODS: The medical records of patients who underwent PKP at Menelik II Hospital between September 2000 and September 2013 were retrospectively reviewed. The prespecified outcomes were graft survival, visual acuity, and complication rates. RESULTS: A total of 321 patients underwent PKP during the study period and were included in the analysis...
March 31, 2017: Cornea
https://www.readbyqxmd.com/read/28366804/effect-of-surfactant-chain-length-on-drug-release-kinetics-from-microemulsion-laden-contact-lenses
#16
Furqan A Maulvi, Ankita R Desai, Harsh H Choksi, Rahul J Patil, Ketan M Ranch, Bhavin A Vyas, Dinesh O Shah
The effect of surfactant chain lengths [sodium caprylate (C8), Tween 20 (C12), Tween 80 (C18)] and the molecular weight of block copolymers [Pluronic F68 and Pluronic F 127] were studied to determine the stability of the microemulsion and its effect on release kinetics from cyclosporine-loaded microemulsion-laden hydrogel contact lenses in this work. Globule size and dilution tests (transmittance) suggested that the stability of the microemulsion increases with increase in the carbon chain lengths of surfactants and the molecular weight of pluronics...
March 31, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28366683/multifocal-intraocular-lenses-an-overview
#17
REVIEW
Jorge Alio, Ana B Plaza-Puche, Roberto Férnandez-Buenaga, Joseph Pikkel, Miguel Maldonado
Multifocal intraocular lenses (MfIOLs) are increasingly used in the management of pseudophakic presbyopia. After MfIOL implantation, most patients do not need spectacles or contact lenses and are pleased with the result. Complications, however, may affect the patient's quality of life and level of satisfaction. Common problems with multifocal lenses are blurred vision and photic phenomena associated with residual ammetropia, posterior capsule opacification, large pupil size, wavefront anomalies, dry eye, and lens decentration...
March 30, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28365053/-contact-lens-care-and-maintenance
#18
REVIEW
L Bloise
All contact lenses with replacement schedules longer than daily must be maintained. At each step of their use, the lenses may be contaminated. Contact lens solutions perform the essential functions of cleaning, decontaminating and preserving the lenses to prevent infectious problems and improve wearing comfort. Contact lens contamination essentially comes from hands, cleaning solutions, cases, water and the environment. The pathogenic microorganisms are mainly Gram-negative bacteria, fungi and amoebae. Contact lens deposits may or may not have an organic origin...
April 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28358216/evaluation-of-the-safety-and-tolerability-of-conjunctival-ring-for-posterior-segment-of-the-eye
#19
Satoshi Kinoshita, Takeshi Ohguchi, Kousuke Noda, Miyuki Murata, Shin-Ichi Yasueda, Haruka Obata, Toru Matsunaga, Tsutomu Fukushima, Atsuhiro Kanda, Susumu Ishida
PURPOSE: To evaluate the safety and tolerability of conjunctival rings (CRs), a novel device for drug delivery to the posterior segment of the eye. METHODS: In animal studies, CRs containing 5% dexamethasone sodium phosphate (DSP) or vehicle solution were placed on the right and left eyes of C57BL/6J mice, respectively. Contact lenses (CLs) containing vehicle solution were used as a control. Twenty-four hours after placement of the CRs, corneal fluorescein staining was graded based on the McDonald-Shadduck scoring system, ranging from 0 to 4...
March 30, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28350622/keratitis-due-to-achromobacter-xylosoxidans-in-a-contact-lens-user
#20
Cristina Almenara Michelena, María Ángeles Del Buey, Francisco Javier Ascaso, Jose Ángel Cristóbal
OBJECTIVES: Ocular infections due to Achromobacter xylosoxidans are extremely uncommon; their diagnosis is a challenge and the optimal treatment remains controversial. We present a case of A. xylosoxidans in a contact lens user and a review of the literature to facilitate diagnostic suspicion and empirical therapeutic management. METHODS: Review of the literature in PubMed and MEDLINE. We also document a case diagnosed in our department in January 2016. SETTING: Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain...
March 27, 2017: Eye & Contact Lens
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