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https://www.readbyqxmd.com/read/28218002/biofilm-formation-of-achromobacter-xylosoxidans-on-contact-lens
#1
Neda Konstantinović, Ivana Ćirković, Slobodanka Đukić, Vesna Marić, Dragana D Božić
Achromobacter spp. may contaminate lenses, lens cases, and contact lens solutions and cause ocular infections. The aim of this study was to investigate the possibility of isolated strain of Achromobacter xylosoxidans to form biofilm on the surface of soft contact lenses (CL), to quantify the production of the formed biofilm, and compare it with the reference strains (Pseudomonas aeruginosa, Staphylococcus aureus, and Haemophilus influenzae). Bacterial strain isolated from one contact lens case was identified as A...
February 20, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28215499/near-binocular-visual-function-in-young-adult-orthokeratology-versus-soft-contact-lens-wearers
#2
Kate Gifford, Paul Gifford, Peter L Hendicott, Katrina L Schmid
PURPOSE: To compare near point binocular vision function of young adult myopes wearing orthokeratology (OK) lenses to matched single vision soft disposable contact lens (SCL) wearers. METHODS: A retrospective clinical record analysis of all OK wearers (18-30 years) presenting over an 18 month period was undertaken. Data was extracted for 17 OK wearers, with 17 SCL wearers matched for age, refractive error and duration of contact lens wear. Binocular vision data included horizontal phoria (phoria), horizontal base-in (BIFR) and base-out fusional reserves (BOFR) and accommodation accuracy (AA)...
February 15, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28212157/current-approaches-to-myopia-control
#3
Seo Wei Leo
PURPOSE OF REVIEW: Myopia is a global problem, being particularly prevalent in the urban areas of east and southeast Asia. In addition to the direct economic and social burdens, associated ocular complications may lead to substantial vision loss. With prevalence of myopia above 80% and high myopia over 20%, it is crucial to control myopia. The aim of this review to is provide an update on the interventions to slow the onset of myopia and retard its progression. RECENT FINDINGS: The epidemic of myopia is characterized by increasingly early onset, combined with high myopia progression rates...
February 15, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28208213/the-correction-of-static-and-dynamic-aniseikonia-with-spectacles-and-contact-lenses
#4
Suzanne McNeill, William R Bobier
No abstract text is available yet for this article.
February 16, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28199121/smart-contact-lenses-with-graphene-coating-for-electromagnetic-interference-shielding-and-dehydration-protection
#5
Sangkyu Lee, Insu Jo, Sangmin Kang, Bongchul Jang, Joonhee Moon, Jong Bo Park, Soochang Lee, Sichul Rho, Youngsoo Kim, Byung Hee Hong
Recently, smart contact lenses with electronic circuits have been proposed for various sensor and display applications where the use of flexible and biologically stable electrode materials is essential. Graphene is an atomically thin carbon material with a two-dimensional hexagonal lattice that shows outstanding electrical and mechanical properties as well as excellent biocompatibility. In addition, graphene is capable of protecting eyes from electromagnectic (EM) waves that may cause eye diseases such as cataracts...
February 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28198731/a-review-of-techniques-to-measure-protein-sorption-to-soft-contact-lenses
#6
Brad Hall, James A Forrest, Lyndon Jones
PURPOSE: To compare and critically evaluate a variety of techniques to measure the quantity and biological activity of protein sorption to contact lenses over short time periods. METHODS: A literature review was undertaken investigating the major techniques to measure protein sorption to soft contact lens materials, with specific reference to measuring protein directly on lenses using in situ, ex situ, protein structural, and biological activity techniques. RESULTS: The use of in situ techniques to measure protein quantity provides excellent sensitivity, but many are not directly applicable to contact lenses...
February 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28197998/laser-assisted-subepithelial-keratectomy-lasek-versus-laser-assisted-in-situ-keratomileusis-lasik-for-correcting-myopia
#7
REVIEW
Jocelyn Kuryan, Anjum Cheema, Roy S Chuck
BACKGROUND: Near-sightedness, or myopia, is a condition in which light rays entering the eye along the visual axis focus in front of the retina, resulting in blurred vision. Myopia can be treated with spectacles, contact lenses, or refractive surgery. Options for refractive surgery include laser-assisted subepithelial keratectomy (LASEK) and laser-assisted in-situ keratomileusis (LASIK). Both procedures utilize a laser to shape the corneal tissue (front of the eye) to correct refractive error, and both create flaps before laser treatment of corneal stromal tissue...
February 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28195489/composition-and-stability-of-plasma-polymer-films-exhibiting-vertical-chemical-gradients
#8
Patrick Rupper, Marianne Vandenbossche, Laetitia Bernard, Dirk Hegemann, Manfred Heuberger
Controlling the balance between stability and functional group density in grown plasma polymer films is the key to diverse applications such as drug release, tissue-engineered implants, filtration, contact lenses, microfluidics, electrodes, sensors, etc. Highly functional plasma polymer films typically show a limited stability in air or aqueous environments due to mechanisms like molecular reorganization, oxidation, and hydrolysis. Stabilization is achieved by enhancing cross-linking at the cost of the terminal functional groups such as -OH and -COOH, but also -NH2, etc...
February 21, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28194876/biocidal-efficacy-of-multipurpose-solutions-against-gram-negative-organisms-associated-with-corneal-infiltrative-events
#9
Denise Callahan, Christopher Kovacs, Shawn Lynch, Marjorie Rah
BACKGROUND: Because corneal infiltrative events (CIEs) may result from bacterial components on contact lenses, which can come from contaminated lens cases, we evaluated the biocidal efficacy of five multipurpose solutions against Gram-negative commonly isolated and CIE-associated organisms. METHODS: Of the multipurpose solutions tested, one contained polyhexamethylene biguanide (PHMB)/polyquaternium-1 (PQ-1; Bausch & Lomb Incorporated: Biotrue), one contained alexidine dihydrochloride (alexidine)/PQ-1 (AMO: RevitaLens OcuTec) and three contained PQ-1/myristamidopropyl dimethylamine (MAPD; Alcon: Opti-Free PureMoist, PQ-1/MAPD-1; Opti-Free RepleniSH, PQ-1/MAPD-2; Opti-Free Express, PQ-1/MAPD-3)...
February 14, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28190731/early-binocular-input-is-critical-for-development-of-audiovisual-but-not-visuotactile-simultaneity-perception
#10
Yi-Chuan Chen, Terri L Lewis, David I Shore, Daphne Maurer
Temporal simultaneity provides an essential cue for integrating multisensory signals into a unified perception. Early visual deprivation, in both animals and humans, leads to abnormal neural responses to audiovisual signals in subcortical and cortical areas [1-5]. Behavioral deficits in integrating complex audiovisual stimuli in humans are also observed [6, 7]. It remains unclear whether early visual deprivation affects visuotactile perception similarly to audiovisual perception and whether the consequences for either pairing differ after monocular versus binocular deprivation [8-11]...
February 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28188995/development-of-ciprofloxacin-loaded-contact-lenses-using-fluorous-chemistry
#11
Guoting Qin, Zhiling Zhu, Siheng Li, Alison M McDermott, Chengzhi Cai
In this work, we developed a simple method to load drugs into commercially available contact lenses utilizing fluorous chemistry. We demonstrated this method using model compounds including fluorous-tagged fluorescein and antibiotic ciprofloxacin. We showed that fluorous interactions facilitated the loading of model molecules into fluorocarbon-containing contact lenses, and that the release profiles exhibited sustained release. Contact lenses loaded with fluorous-tagged ciprofloxacin exhibited antimicrobial activity against Pseudomonas aeruginosa in vitro, while no cytotoxicity towards human corneal epithelial cells was observed...
January 31, 2017: Biomaterials
https://www.readbyqxmd.com/read/28181225/electrophysiological-evidence-of-altered-visual-processing-in-adults-who-experienced-visual-deprivation-during-infancy
#12
Sidney J Segalowitz, Avital Sternin, Terri L Lewis, Jane Dywan, Daphne Maurer
We examined the role of early visual input in visual system development by testing adults who had been born with dense bilateral cataracts that blocked all patterned visual input during infancy until the cataractous lenses were removed surgically and the eyes fitted with compensatory contact lenses. Patients viewed checkerboards and textures to explore early processing regions (V1, V2), Glass patterns to examine global form processing (V4), and moving stimuli to explore global motion processing (V5). Patients' ERPs differed from those of controls in that (1) the V1 component was much smaller for all but the simplest stimuli and (2) extrastriate components did not differentiate amongst texture stimuli, Glass patterns, or motion stimuli...
February 9, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/28179956/glucose-responsive-hydrogel-electrode-for-biocompatible-glucose-transistor
#13
Taira Kajisa, Toshiya Sakata
In this paper, we propose a highly sensitive and biocompatible glucose sensor using a semiconductor-based field effect transistor (FET) with a functionalized hydrogel. The principle of the FET device contributes to the easy detection of ionic charges with high sensitivity, and the hydrogel coated on the electrode enables the specific detection of glucose with biocompatibility. The copolymerized hydrogel on the Au gate electrode of the FET device is optimized by controlling the mixture ratio of biocompatible 2-hydroxyethylmethacrylate (HEMA) as the main monomer and vinylphenylboronic acid (VPBA) as a glucose-responsive monomer...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28178141/a-non-surgical-approach-to-the-management-of-exposure-keratitis-due-to-facial-palsy-by-using-mini-scleral-lenses
#14
Victor Zaki
RATIONALE: This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy. PATIENT CONCERNS: Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. If left untreated, it leads to permanent damage to the cornea and loss of good functional vision. Mini-scleral lens keep the cornea covered by saline solution all wearing hours...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28177597/zero-order-antibiotic-release-from-multilayer-contact-lenses-nonuniform-drug-and-diffusivity-distributions-produce-constant-rate-drug-delivery
#15
Gustavo Guzman, Siamak Shams Es-Haghi, Turgut Nugay, Mukerrem Cakmak
A novel approach to zero-order constant-rate drug delivery from contact lenses is presented. Quasi-Case II non-Fickian transport is achieved by nonuniform drug and diffusivity distributions within three-layer bimodal amphiphilic conetworks (β-APCNs). The center layer is a highly oxygen permeable β-APCN matrix, which contains the drug and exhibits a high drug diffusivity. The outer β-APCN layers contain no-drug and are loaded with vitamin E, which slows diffusion. In contrast to single-layer neat-polymer and vitamin E-loaded films that display first-order "burst" kinetics, it is demonstrated experimentally and by modeling that the combined effect of nonuniform distribution of drug loading and diffusion constants within the three-layer lens maintains low local drug concentration at the lens-fluid interface and yields zero-order drug delivery...
February 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28176379/care-solution-effects-on-contact-lens-in-vivo-wettability
#16
Raied Fagehi, E Ian Pearce, Katherine Oliver, Ali A Abusharha, Alan Tomlinson
BACKGROUND: The aim of the study was to evaluate the effect of care solutions on contact lens in vivo wettability using Doane's interferometric technique. METHODS: Thirteen subjects (aged 26.6 ± 6.3 years) participated for contact lens wettability evaluation after soaking in five care solutions namely Opti-Free EverMoist (now called puremoist), Opti-Free Express (Alcon), COMPLETE (AMO), ReNu and Biotrue (Bausch & Lomb). A new pair of lenses was soaked in the solutions for eight hours (prior to wear) or taken directly from pack solutions (as control) and worn by the subjects...
February 8, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28166436/interventions-to-reduce-myopia-progression-in-children
#17
Su Ann Tay, Sonal Farzavandi, Donald Tan
Efforts to reduce the progression of myopia in childhood are on the rise, due to an increasing incidence of myopia worldwide and its associated sight-threatening complications. Interventions are aimed at reducing myopia in childhood and include environmental considerations, spectacles, contact lenses, and pharmacological agents. We reviewed recent literature with interventions aimed at reducing myopia progression in children and found that a number of interventions were significant in reducing the progression of myopia...
February 6, 2017: Strabismus
https://www.readbyqxmd.com/read/28166430/effect-of-rigid-gas-permeable-contact-lenses-on-nystagmus-and-visual-function-in-hyperopic-patients-with-infantile-nystagmus-syndrome
#18
Abbas Bagheri, Hamed Abbasi, Mehdi Tavakoli, Abdolreza Sheibanizadeh, Bahareh Kheiri, Shahin Yazdani
PURPOSE: To determine the effect of rigid gas permeable contact lenses (RGPCL) on involuntary eye movements and visual function in hyperopic patients with infantile nystagmus syndrome. METHODS: This prospective interventional case series was conducted on 16 patients with infantile nystagmus and hyperopia equal or more than +0.5 D and astigmatism more than -1 D over a 2-year period. A complete ophthalmological examination including determination of best corrected visual acuity (BCVA), contrast sensitivity, and videonystagmography was performed for all patients before and after at least 3 months of RGPCL use, and the outcomes were compared...
February 6, 2017: Strabismus
https://www.readbyqxmd.com/read/28149785/objective-assessment-of-the-effect-of-pupil-size-upon-the-power-distribution-of-multifocal-contact-lenses
#19
Eleni Papadatou, Antonio J Del Águila-Carrasco, José J Esteve-Taboada, David Madrid-Costa, Alejandro Cerviño-Expósito
AIM: To analytically assess the effect of pupil size upon the refractive power distributions of different designs of multifocal contact lenses. METHODS: Two multifocal contact lenses of center-near design and one multifocal contact lens of center-distance design were used in this study. Their power profiles were measured using the NIMO TR1504 device (LAMBDA-X, Belgium). Based on their power profiles, the power distribution was assessed as a function of pupil size...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28140621/effects-of-lactoferrin-on-the-viability-and-the-encystment-of-acanthamoeba-trophozoites
#20
Shinichi Tomita, Chie Suzuki, Hitomi Wada, Miya Nomachi, Masaki Imayasu, Kaoru Araki-Sasaki
Lactoferrin (LF) is an iron-binding basic glycoprotein that has an antimicrobial effect against certain microbes. The purpose of this study is to evaluate the amoebicidal effect of bovine milk LF (bLF) against Acanthamoeba clinical-isolate trophozoites, which cause severe keratitis. Most of the risk factor for Acanthamoeba keratitis is from wearing soft contact lenses (SCLs). Acanthamoeba trophozoites were incubated in bovine LF (bLF) solution, and the ratios of viability and encystment were determined with microscopic analysis of cyst formation...
February 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
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