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https://www.readbyqxmd.com/read/29162075/the-antibiofilm-efficacy-of-nitric-oxide-on-soft-contact-lenses
#1
Dong Ju Kim, Joo-Hee Park, Marth Kim, Choul Yong Park
BACKGROUND: To investigate the antibiofilm efficacy of nitric oxide (NO) on soft contact lenses. METHODS: Nitrite (NO precursor) release from various concentrations (0-1000 μM) of sodium nitrite (NaNO2, NO donor) was measured by Griess Assay. Cell viability assay was performed using human corneal epithelial cell under various concentration (0-1000 μM) of NaNO2. Biofilm formation on soft contact lenses was achieved by adding Staphylococcus aureus or Pseudomonas aeruginosa to the culture media...
November 21, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29161310/vision-in-high-level-football-officials
#2
António Manuel Gonçalves Baptista, Pedro M Serra, Colm McAlinden, Brendan T Barrett
Officiating in football depends, at least to some extent, upon adequate visual function. However, there is no vision standard for football officiating and the nature of the relationship between officiating performance and level of vision is unknown. As a first step in characterising this relationship, we report on the clinically-measured vision and on the perceived level of vision in elite-level, Portuguese football officials. Seventy-one referees (R) and assistant referees (AR) participated in the study, representing 92% of the total population of elite level football officials in Portugal in the 2013/2014 season...
2017: PloS One
https://www.readbyqxmd.com/read/29160536/use-of-the-ishikawa-diagram-in-a-case-control-analysis-to-assess-the-causes-of-a-diffuse-lamellar-keratitis-outbreak
#3
Luis Henrique Lira, Flávio E Hirai, Marivaldo Oliveira, Waldir Portellinha, Eliane Mayumi Nakano
PURPOSE: To identify the causes of a diffuse lamellar keratitis (DLK) outbreak using a systematic search tool in a case-control analysis. METHODS: An Ishikawa diagram was used to guide physicians to determine the potential risk factors involved in this outbreak. Coherence between the occurrences and each possible cause listed in the diagram was verified, and the total number of eyes at risk was used to calculate the proportion of affected eyes. Multivariate analysis was performed using logistic regression to determine the independent effect of the risk factors, after controlling for confounders and test interactions...
September 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29152910/treating-amblyopia-in-adults-with-prosthetic-occluding-contact-lenses
#4
Esperanza Garcia-Romo, Consuelo Perez-Rico, Isabel Roldán-Díaz, Juan Arévalo-Serrano, Román Blanco
PURPOSE: To investigate the feasibility, effectiveness and acceptability of using prosthetic occluding contact lenses (OCLs) to treat moderate amblyopia in adults and of the role of the multifocal visual evoked potential (mfVEP) as a predictor of postamblyopic therapy. METHODS: A comparative, prospective, interventional, case series pilot study with amblyopic adults (mean age: 40 years, range 20-50 years) allocated into two intervention groups: eye patching and OCL...
November 20, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29152742/presbyopia-monovision-correction-and-cortical-adaptation
#5
Andreia Martins Rosa
The article "Immediate cortical adaption in visual and non-visual areas functions induced by monovision" approaches adaptation to monovision with contact lenses, one way of compensating the loss of near vision that affects all humans with ageing. This article is protected by copyright. All rights reserved.
November 19, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29150218/keratitis-secondary-to-fusarium-spp-in-spain-2012-2014
#6
M A Mosquera Gordillo, N Barón Cano, A Garralda Luquin, C López Gutiérrez, E Mengual Verdú, G Trujillo Cabrera, J M Garrido Fierro, J Lamarca Mateu, J C Sánchez España, P Marticorena Álvarez, R Feijoó Lera, S Martín Nalda, T Marti Huguet, V Gacía Conca
OBJECTIVE: To describe the clinical-epidemiological characteristics of a case series of fungal keratitis associated with Fusarium spp.., in Spain during the years 2012 to 2014. METHODS: A retrospective study of a case series was conducted on a systematic random sample of 10% of patients identified in Health Centres of provincial capitals (n=250). The centres were asked whether they had been presented with cases of Fusarium spp. keratitis characterised by microbiological methods...
November 14, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29133630/non-contact-lens-related-acanthamoeba-keratitis
#7
REVIEW
Prashant Garg, Paavan Kalra, Joveeta Joseph
The purpose of the study is to describe epidemiology, clinical features, diagnosis, and treatment of Acanthamoeba keratitis (AK) with special focus on the disease in nonusers of contact lenses (CLs). This study was a perspective based on authors' experience and review of published literature. AK accounts for 2% of microbiology-proven cases of keratitis. Trauma and exposure to contaminated water are the main predisposing factors for the disease. Association with CLs is seen only in small fraction of cases. Contrary to classical description experience in India suggests that out of proportion pain, ring infiltrate, and radial keratoneuritis are seen in less than a third of cases...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29132114/drug-eluting-silicone-hydrogel-for-therapeutic-contact-lenses-impact-of-sterilization-methods-on-the-system-performance
#8
Raquel Galante, Andreia S Oliveira, Ana Topete, Daniela Ghisleni, Marina Braga, Terezinha J A Pinto, Rogério Colaço, Ana Paula Serro
Although contact lenses are promising platforms for ocular drug delivery and have been extensively studied for that purpose, the influence of sterilization methods on these systems remains barely investigated. In this work, a silicone-based hydrogel was produced and loaded with different ophthalmic drugs: levofloxacin, chlorhexidine, diclofenac and timolol. The drug release profiles, along with several material properties, were evaluated before and after sterilization by three different methods steam heat, γ-irradiation and ozone gas...
November 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29129479/an-analysis-of-anterior-scleral-shape-and-its-role-in-the-design-and-fitting-of-scleral-contact-lenses
#9
Markus Ritzmann, Patrick J Caroline, Rainer Börret, Emily Korszen
PURPOSE: The purpose of this study was to evaluate the shape of the anterior sclera by measuring the sagittal height and corneoscleral transition angles in the four cardinal and four oblique segments of the eye. MATERIALS AND METHODS: In this study, 78 normal eyes of 39 subjects were evaluated. The sagittal height, corneoscleral angle and scleral angle were measured at three chord lengths (10.0mm, 12.8mm and 15.0mm) in all eight segments of the anterior eye using optical coherence tomography (Zeiss Visante AS-OCT)...
November 9, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29124780/refractive-error-and-vision-correction-in-a-general-sports-playing-population
#10
Fabrizio Zeri, Sabrina Pitzalis, Assunta Di Vizio, Tiziana Ruffinatto, Fabrizio Egizi, Francesco Di Russo, Richard Armstrong, Shehzad A Naroo
PURPOSE: To evaluate, in an amateur sports-playing population, the prevalence of refractive error, the type of vision correction used during sport and attitudes toward different kinds of vision correction used in various types of sports. METHOD: A questionnaire was used for people engaging in sport and data was collected from sport centres, gyms and universities that focused on the motor sciences. RESULTS: One thousand, five hundred and seventy-three questionnaires were collected (mean age 26...
November 9, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29116965/mechanical-properties-of-contact-lens-materials
#11
Eon Kim, Mou Saha, Klaus Ehrmann
OBJECTIVES: To evaluate the mechanical properties of commonly available soft contact lens materials and compare results using custom-built MicroTensometer. METHODS: The Young modulus, parameters for stress relaxation, and toughness of 18 types of single vision soft contact lenses were measured using custom-built MicroTensometer. Five lenses of each type were soaked in standard phosphate buffered saline and measured at a temperature of 35°C. Each lens was flattened and sliced into a rectangular strip sample using two parallel blades...
November 7, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29107055/native-and-synthetic-scaffolds-for-limbal-epithelial-stem-cell-transplantation
#12
REVIEW
Kim N Nguyen, Samantha Bobba, Alexander Richardson, Mijeong Park, Stephanie L Watson, Denis Wakefield, Nick Di Girolamo
Limbal stem cell deficiency (LSCD) is a complex blinding disease of the cornea, which cannot be treated with conventional corneal transplants. Instead, a stem cell (SC) graft is required to replenish the limbal epithelial stem cell (LESC) reservoir, which is ultimately responsible for regenerating the corneal epithelium. Current therapies utilize limbal tissue biopsies that harbor LESCs as well as tissue culture expanded cells. Typically, this tissue is placed on a scaffold that supports the formation of corneal epithelial cell sheets, which are then transferred to diseased eyes...
November 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29091618/surface-defect-analysis-on-formed-chalcogenide-glass-ge22se58as20-lenses-after-the-molding-process
#13
Tianfeng Zhou, Qin Zhou, Jiaqing Xie, Xiaohua Liu, Xibin Wang, Haihui Ruan
Chalcogenide glass (ChG) is increasingly used in infrared optical systems owing to its excellent infrared optical properties and scalable production using precision glass molding (PGM). However, surface scratches affected by the molding temperature and microdimples on the lens surface caused by gas release seriously impair the quality of the formed lens. To reduce these surface defects when molding Ge22Se58As20 ChG, the temperature effect must be studied, and the gas generation must be minimized, while the gas escape must be maximized...
October 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/29082635/changing-the-size-of-a-mirror-reflected-hand-does-not-affect-pain-perception-a-repeated-measures-study-on-healthy-human-participants
#14
P G Wittkopf, D M Lloyd, M I Johnson
BACKGROUND: Studies suggest that observing magnified and minified body parts using mirrors, lenses and virtual reality may affect pain perception. However, the direction of effect varies between studies. The aim of the present study was to evaluate the effect of observing a normal-sized, magnified and minified reflection of a hand on perceptual embodiment and contact-heat stimuli. METHODS: Participants (n = 46) observed a normal-sized, magnified and minified reflection of the hand and a no-reflection condition while performing synchronized finger movements for 3 min (adaptive phase)...
October 30, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29082121/bilateral-posterior-crystalline-lens-dislocations-in-an-otherwise-healthy-child
#15
Omar A AlShehri, Hashem Almarzouki, Badr A Alharbi, Mohammed Alqahtani, Khaled Allam
Introduction: Ectopia lentis is defined as a crystalline lens displacement, either partially or completely, due to zonular abnormalities. It can be a result of trauma, hereditary ocular disease, or part of systemic diseases, like Marfan syndrome and homocystinuria. Case description: We report a case of a medically free 16-year-old girl, who was referred to our hospital complaining of poor vision and a squint in both eyes since childhood. Her history included a traffic accident when she was one-year-old. She was previously diagnosed with alternating esotropia, which was treated with glasses, alternating patching, and bilateral Botox injections...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/29079419/epalrestat-loaded-silicone-hydrogels-as-contact-lenses-to-address-diabetic-eye-complications
#16
Fernando Alvarez-Rivera, Angel Concheiro, Carmen Alvarez-Lorenzo
Most treatments for diabetic eye conditions rely on systemic (oral) or intravitreal administration, and there is still a demand of efficient and comfortable ocular dosage forms. Our purpose was to design contact lenses (CLs) suitable for local prophylaxis/treatment of diabetes-related ocular pathologies, by means of the incorporation of bioinspired functional groups that can reversibly interact with epalrestat, an aldose reductase inhibitor. Several sets of silicone hydrogels were synthesized varying the contents in 2-hydroxyethyl methacrylate (HEMA), monomethacryloxypropyl-sym-polydimethylsiloxane hydroxypropyl terminated (MCS-MC12), and aminopropyl methacrylamide (APMA)...
October 24, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29077584/comfort-ocular-dryness-and-equilibrium-water-content-changes-of-daily-disposable-contact-lenses
#17
Eduardo Insua Pereira, Madalena Lira
OBJECTIVES: The objective of this investigation was to evaluate the level of comfort and ocular dryness during wear with six daily disposable contact lenses (DDCL) and also determine the changes in contact lens equilibrium water content (EWC) resulting from their wear. METHODS: In this contralateral open trial, 27 subjects were randomly fitted with six DDCL (stenfilcon A, delefilcon A, nelfilcon A, narafilcon A, nesofilcon A, and omafilcon A). The evaluation of comfort and ocular dryness sensation was recorded by the participants at two moments of the day (11 AM and 5 PM) over a period of 10 days of contact lens wear...
October 26, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29074266/effective-diffusion-coefficients-of-dnapl-waste-components-in-saturated-low-permeability-soil-materials
#18
Derya Ayral-Cinar, Avery H Demond
Diffusion is regarded as the dominant transport mechanism into and out of low permeable subsurface lenses and layers in the subsurface. But, some reports of mass storage in such zones are higher than what might be attributable to diffusion, based on estimated diffusion coefficients. Despite the importance of diffusion to efforts to estimate the quantity of residual contamination in the subsurface, relatively few studies present measured diffusion coefficients of organic solutes in saturated low permeability soils...
September 23, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/29071723/immediate-cortical-adaptation-in-visual-and-non-visual-areas-functions-induced-by-monovision
#19
Fabrizio Zeri, Marika Berchicci, Shehzad A Naroo, Sabrina Pitzalis, Francesco Di Russo
KEY POINTS: Monovision is an optical correction for presbyopes that consists of correcting one eye for far distance and the other for near distance, creating a superimposition of an in-focus with a blurred image. Brain adaptation to monovision was studied in unexperienced observers by measuring visual evoked potentials from 64-channels. The first clear effect of monovision on visual evoked potentials was the C1 amplitude reduction, indicating that the unilateral blurring induced by monovision reduces feed-forward activity in primary visual area...
October 25, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29067921/photokeratitis-induced-by-ultraviolet-radiation-in-travelers-a-major-health-problem
#20
REVIEW
M Izadi, N Jonaidi-Jafari, M Pourazizi, M H Alemzadeh-Ansari, M J Hoseinpourfard
Ultraviolet (UV) irradiation is one of the several environmental hazards that may cause inflammatory reactions in ocular tissues, especially the cornea. One of the important factors that affect how much ultraviolet radiation (UVR) humans are exposed to is travel. Hence, traveling is considered to include a more acute UVR effect, and ophthalmologists frequently evaluate and manage the ocular manifestations of UV irradiation, including UV-induced keratitis. The purpose of this paper is to provide an evidence-based analysis of the clinical effect of UVR in ocular tissues...
October 23, 2017: Journal of Postgraduate Medicine
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