Shahin Isha, Parthkumar H Satashia, Siva Naga S Yarrarapu, Austin B Govero, Michael F Harrison, Hassan Z Baig, Pramod Guru, Anirban Bhattacharyya, Colleen T Ball, Sean M Caples, Ami A Grek, Michael R Vizzini, Syed Anjum Khan, Katherine J Heise, Hiroshi Sekiguchi, Warren L Cantrell, Jeffrey D Smith, Sanjay Chaudhary, Karthik Gnanapandithan, Kristine M Thompson, Charles G Graham, Jed C Cowdell, Aleksandra Murawska Baptista, Claudia R Libertin, Pablo Moreno Franco, Devang K Sanghavi
BACKGROUND: The Surviving Sepsis Campaign suggested preferential resuscitation with balanced crystalloids, such as Lactated Ringer's (LR), although the level of recommendation was weak, and the quality of evidence was low. Past studies reported an association of unbalanced solutions, such as normal saline (NS), with increased AKI risks, metabolic acidosis, and prolonged ICU stay, although some of the findings are conflicting. We have compared the outcomes with the preferential use of normal saline vs...
2023: Frontiers in Medicine