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https://www.readbyqxmd.com/read/29132434/an-acetabular-preserving-procedure-for-pelvic-giant-cell-tumor-involving-partial-acetabulum
#1
Cong Xiao, Yong Zhou, Wenli Zhang, Yi Luo, Chongqi Tu
BACKGROUND: The management of pelvic giant cell tumors (GCTs) involving the acetabulum remains a challenge for surgeons on how to balance the relative benefits of minimizing recurrence and maintaining postoperative hip function. The present study was to present and evaluate the clinical indications, operative technique, and outcomes of pelvic GCTs involving partial acetabulum treated with multiplanar osteotomy and reconstruction of autogenous femoral head bone grafts combined with cementless total hip arthroplasty (THA)...
November 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29132347/knee-arthrodesis-versus-above-the-knee-amputation-after-septic-failure-of-revision-total-knee-arthroplasty-comparison-of-functional-outcome-and-complication-rates
#2
Sven Hungerer, Martin Kiechle, Christian von Rüden, Matthias Militz, Knut Beitzel, Mario Morgenstern
BACKGROUND: After septic failure of total knee arthroplasty (TKA) and multiple revision operations resulting in impaired function, bone and/or soft-tissue damage a reconstruction with a revision arthroplasty might be impossible. Salvage procedures to regain mobility and quality of life are an above-the-knee amputation or knee arthrodesis. The decision process for the patient and surgeon is difficult and data comparing arthrodesis versus amputation in terms of function and quality of life are scarce...
November 13, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29111313/prevalence-and-confounders-of-chronic-endometritis-in-premenopausal-women-with-abnormal-bleeding-or-reproductive-failure
#3
Dongmei Song, Xiangdong Feng, Qian Zhang, Enlan Xia, Yu Xiao, Wei Xie, Tin Chiu Li
In this retrospective cohort study, a consecutive series of 1551 premenopausal women underwent hysteroscopy and endometrial biopsy. Chronic endometritis was diagnosed when plasma cell in endometrial tissue was detected by immunohistochemistry using CD138 epitope. The overall prevalence of chronic endometritis in the population studied was 24.4% The prevalence was significantly increased in the following conditions: recurrent implantation failure (40.8%; P < 0.001), abnormal uterine bleeding (40.7 %; P < 0...
October 6, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29093507/identifying-stably-expressed-housekeeping-genes-in-the-endometrium-of-fertile-women-women-with-recurrent-implantation-failure-and-recurrent-miscarriages
#4
Linden Stocker, Felino Cagampang, Ying Cheong
Housekeeping genes (HKG) are presumed to be constitutively expressed throughout tissue types but recent studies have shown they vary with pathophysiology. Often, validation of appropriate HKG is not made. There is no consensus on which HKGs are most stably expressed in endometrial tissue so this study aimed to identify the most stable HKG in the endometrium of women with recurrent implantation failure (RIF) and recurrent miscarriages (RM). Inclusion criteria were women between 25-45 years (n = 45) suffering recurrent miscarriage (RM), recurrent implantation failure (RIF) or fertile controls...
November 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29073227/the-methylenetetrahydrofolate-reductase-c-c-677-c-t-and-c-c-1298-a-c-polymorphisms-in-reproductive-failures-experience-from-an-rsa-and-rif-study-on-a-polish-population
#5
Izabela Nowak, Aleksandra Bylińska, Karolina Wilczyńska, Andrzej Wiśniewski, Andrzej Malinowski, Jacek R Wilczyński, Paweł Radwan, Michał Radwan, Ewa Barcz, Rafał Płoski, Hanna Motak-Pochrzęst, Małgorzata Banasik, Maciej Sobczyński, Piotr Kuśnierczyk
Almost 1600 individuals from the Polish population were recruited to this study. Among them 319 were fertile couples, 289 were recurrent spontaneous abortion (RSA) couples, and 131 were in the group of recurrent implantation failure (RIF) following in vitro fertilization. The aim of this study was to evaluate the MTHFR c.c.677 C>T and c.c.1298 A>C polymorphisms' association with RSA and RIF. We used PCR-RFLP with HinfI (677 C>T) and MboII (1298 A>C) digestion. We observed a protective effect of the female AC genotype (OR = 0...
2017: PloS One
https://www.readbyqxmd.com/read/29072989/persistence-of-icd-indication-at-the-time-of-replacement-in-patients-with-initial-implant-for-primary-prevention-indication-effect-on-subsequent-icd-therapies
#6
Gabriele Dell'Era, Anna Degiovanni, Eraldo Occhetta, Andrea Magnani, Miriam Bortnik, Gabriella Francalacci, Laura Plebani, Eleonora Prenna, Sergio Valsecchi, Paolo Marino
BACKGROUND: Indication to implantable cardioverter defibrillator (ICD) for primary prevention of sudden death relies on left ventricular ejection fraction (LVEF). We measured the proportion of patients in whom indication to ICD persisted at the time of generator replacement (GR) and searched for predictors of appropriate therapies after GR. METHODS: We identified all consecutive patients who had received an ICD at our hospital, for LVEF ≤35% and no previous arrhythmias or unexplained syncope...
March 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29068537/anti-fibrotic-function-of-cu-bearing-stainless-steel-for-reducing-recurrence-of-urethral-stricture-after-stent-implantation
#7
Jing Zhao, Ling Ren, Meixia Liu, Tong Xi, Bingchun Zhang, Ke Yang
Recurrent stenosis is the main reason inducing the failure of urethral stricture treatment. Our previous study has found that the 316L type Cu bearing stainless steel (316L-Cu SS) showed antimicrobial activity and anti-encrustation performance when it was used for relieving urethral obstructer. However, whether it can reduce the occurrence of fibrosis or not, we need further investigation to compare the cellular and molecular responses of human urethral scar fibroblast cells (USFCs) on 316L-Cu SS and medical grade 316L stainless (316L SS, as a control)...
October 25, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29064176/calciphylaxis-after-parathyroidectomy
#8
Sathish Karmegam, Anupkumar Shetty
A 60-year-old African American man with end stage renal disease on hemodialysis (HD) for the past 2.5 years developed severe hyperparathyroidism. Other past medical history included atrial fibrillation, type II diabetes mellitus, hypertension, gout, pericardial effusion needing pericardial window, deep vein thrombosis, mitral insufficiency, and cardiomyopathy with implantable cardioversion device placement. His parathyroid hormone (PTH) level peaked at 4,191 pg/mL despite being on cinacalcet, sevelamer, and paricalcitol...
October 2017: Hemodialysis International
https://www.readbyqxmd.com/read/29063503/are-blastocyst-aneuploidy-rates-different-between-fertile-and-infertile-populations
#9
Jonathan D Kort, Rajiv C McCoy, Zach Demko, Ruth B Lathi
PURPOSE: This study aimed to determine if patients with infertility or recurrent pregnancy loss have higher rates of embryo aneuploidy than fertile controls. METHODS: This was a retrospective review of all pre-implantation genetic screening (PGS) cases processed by a single reference lab prior to March 2014 after a blastocyst biopsy. Cases were excluded if no indication for PGS was designated or patients were translocation carriers. The fertile control group consisted of patients undergoing IVF with PGS for sex selection only...
October 23, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29062792/elevated-levels-of-serum-vascular-endothelial-growth-factor-a-are-not-related-to-nk-cell-parameters-in-recurrent-ivf-failure
#10
Rhea Bansal, Brian Ford, Shree Bhaskaran, Meenyau Thum, Amolak Bansal
BACKGROUND: Vascular Endothelial Growth Factor and NK cells have an interrelated role in angiogenesis that is critical for placentation and success of in vitro fertilization. An attempt was made to assess a possible relationship between the two in this study. METHODS: A case control study was performed comparing the serum levels of VEGF-A and its receptor VEGF-R1 with levels of NK cells, activated NK cells and NK cytotoxicity in 62 women with Repeated Implantation Failure (RIF)...
July 2017: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/29049508/outcomes-in-women-and-minorities-compared-with-white-men-1-year-after-everolimus-eluting-stent-implantation-insights-and-results-from-the-platinum-diversity-and-promus-element-plus-post-approval-study-pooled-analysis
#11
Wayne Batchelor, David E Kandzari, Scott Davis, Luis Tami, John C Wang, Islam Othman, Osvaldo S Gigliotti, Amir Haghighat, Sarabjeet Singh, Mario Lopez, Gregory Giugliano, Phillip A Horwitz, Jaya Chandrasekhar, Paul Underwood, Craig A Thompson, Roxana Mehran
Importance: There exist limited outcomes data for women and minorities after contemporary percutaneous coronary intervention (PCI). Objective: To examine 1-year outcomes in women and minorities vs white men after PCI with everolimus-eluting stents. Design, Settings, and Participants: The PLATINUM Diversity study was a single-arm study enrolling women and minorities. Patient-level pooling with the PROMUS Element Plus Post-Approval Study was prespecified...
October 18, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29048692/effects-of-electrical-stimulation-in-the-treatment-of-osteonecrosis-of-the-femoral-head
#12
Salvador Fornell, Juan Ribera, Mario Mella, Andrés Carranza, David Serrano-Toledano, Gabriel Domecq
INTRODUCTION: The aim of this study was to examine whether the use of an internal electrostimulator could improve the results obtained with core decompression alone in the treatment of osteonecrosis of the femoral head. METHODS: We performed a retrospective study of 41 patients (55 hips) treated for osteonecrosis of the femoral head between 2005 and 2014. Mean follow-up time was 56 (12-108) months. We recorded 3 parameters: time to recurrence of pain, time to conversion to arthroplasty and time to radiographic failure...
October 16, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29043704/accuracy-of-two-dimensional-transvaginal-sonography-and-office-hysteroscopy-for-detection-of-uterine-abnormalities-in-patients-with-repeated-implantation-failures-or-recurrent-pregnancy-loss
#13
Marzieh Shiva, Firouzeh Ahmadi, Arezoo Arabipoor, Mansoureh Oromiehchi, Mohammad Chehrazi
Background: We sought to compare diagnostic values of two-dimensional transvaginal sonography (2D TVS) and office hysteroscopy (OH) for evaluation of endometrial pathologies in cases with repeated implantation failure (RIF) or recurrent pregnancy loss (RPL). MATERIALS AND METHODS: This prospective study was performed at Royan Institute from December 2013 to January 2015. TVS was performed before hysteroscopy as part of the routine diagnostic work-up in 789 patients with RIF or RPL...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29030806/palliative-care-in-the-management-of-patients-with-advanced-heart-failure
#14
Susan E Lowey
Globally, there are 18-million individuals living with heart failure, a disease that is responsible for 12-15 million office visits and 6.5 million inpatient hospitalizations each year. As HF becomes advanced or end-stage, patients often live in a cycle of frequent transitions between care settings, and with unmet needs, including distress from inadequately managed symptoms. Prognostication in patients with heart failure can be challenging due to the unpredictable exacerbating-remitting illness trajectory that is associated with this progressive disease...
October 14, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29029888/reirradiation-using-permanent-interstitial-brachytherapy-a-potentially-durable-technique-for-salvaging-recurrent-pelvic-malignancies
#15
Jonathan Feddock, Dennis Cheek, Cole Steber, Jason Edwards, Stacey Slone, Wei Luo, Marcus Randall
PURPOSE: To present a time-to-failure (TTF) analysis for all patients treated with permanent interstitial brachytherapy (PIB) at our institution, with additional analyses to correlate successful reirradiation and to identify the frequency of severe grade 3 to 4 toxicity. METHODS AND MATERIALS: Forty-two previously irradiated patients received curative or palliative intent PIB for a recurrent pelvic malignancy between January 2009 and August 2016. Minimum follow-up was 6 months after the PIB procedure...
August 26, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29018572/enhanced-hoxa10-sumoylation-inhibits-embryo-implantation-in-women-with-recurrent-implantation-failure
#16
Ruiwei Jiang, Lijun Ding, Jianjun Zhou, Chenyang Huang, Qun Zhang, Yue Jiang, Jingyu Liu, Qiang Yan, Xin Zhen, Jianxin Sun, Guijun Yan, Haixiang Sun
HOXA10 has emerged as an important molecular marker of endometrial receptivity. Recurrent implantation failure (RIF) after in vitro fertilization-embryo transplantation (IVF-ET) treatment is associated with impaired endometrial receptivity, but the exact underlying mechanism of this phenomenon remains elusive. Here we found that HOXA10 was modified by small ubiquitin like-modifier 1 (SUMO1) at the evolutionarily conserved lysine 164 residue. Sumoylation inhibited HOXA10 protein stability and transcriptional activity without affecting its subcellular localization...
2017: Cell Death Discovery
https://www.readbyqxmd.com/read/29018520/prophylactic-catheter-ablation-for-ventricular-tachycardia-are-we-there-yet
#17
Rahul K Mukherjee, Louisa O'Neill, Mark D O'Neill
Ventricular tachycardia (VT), often degenerating into ventricular fibrillation, is the leading cause of sudden cardiac death. Catheter ablation of VT is associated with relatively low, long-term success rates, while the optimal timing of ablation in patients with ischaemic and non-ischaemic cardiomyopathy remains unclear. Contemporary practice in most centres is to consider ablation late in the disease process following the failure of anti-arrhythmic medications and/or following recurrent implantable cardioverter-defibrillator shocks...
August 2017: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29016771/predictors-of-long-term-survival-free-from-relapses-after-extraction-of-infected-cied
#18
Igor Diemberger, Mauro Biffi, Stefano Lorenzetti, Cristian Martignani, Elena Raffaelli, Matteo Ziacchi, Claudio Rapezzi, Davide Pacini, Giuseppe Boriani
Aims: We explored the possible predictors of long-term prognosis after transvenous lead extraction (TLE) for a cardiac implantable device related infection (CIEDI), including the modified Duke score result. Methods and results: We performed a single centre prospective observational study in a population of consecutive patients referred for TLE to a teaching hospital to treat a CIEDI without associated valve-endocarditis. 121 patients were enrolled between January 2012 and March 2016...
August 9, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28993889/recurrent-primary-osseous-hemangiopericytoma-in-the-thoracic-spine-a-case-report-and-literature-review
#19
Takahiro Onoki, Haruo Kanno, Toshimi Aizawa, Ko Hashimoto, Eiji Itoi, Hiroshi Ozawa
PURPOSE: Primary osseous hemangiopericytoma (HPC) of the spine is exceedingly rare. HPC has malignant potential and has the capacity for metastasis and local recurrence. We herein present the first case of recurrent primary osseous HPC in the thoracic spine that was successfully treated by total spondylectomy at three vertebral levels and spinal reconstruction. METHODS: We performed a two-stage operation for recurrent HPC using anterior and posterior approaches at the T5-T7 vertebrae...
October 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28993083/acetabular-revision-arthroplasty-using-an-uncemented-deep-profile-jumbo-component-a-ten-to-sixteen-year-follow-up-study
#20
Jeffrey R McLaughlin, Kyla R Lee
BACKGROUND: The purpose of this study is to evaluate the outcome of revision total hip arthroplasty using an uncemented deep profile jumbo acetabular component in patients who had been followed for a minimum of 10 years postoperatively. METHODS: Between 1997 and 2001, 61 revision total hip arthroplasties were performed in 58 patients, with use of the +5 Deep Profile acetabular shell. The outcome with regard to retention vs re-revision of the acetabular component was determined for every hip...
September 14, 2017: Journal of Arthroplasty
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