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https://www.readbyqxmd.com/read/29774540/conservative-thickness-layers-in-mohs-micrographic-surgery
#1
Stanislav N Tolkachjov, Jonathan A Cappel, Elizabeth A Bryant, Christopher B Harmon
BACKGROUND: Mohs micrographic surgery (MMS) is used to treat cutaneous malignancies in locations to maximize tissue sparing. The authors' aim is to demonstrate the utility of conservative thickness layers (CTL) in MMS and review patient and tumor characteristics and the potential anatomic locations where this technique may be most useful. METHODS: We performed a retrospective chart review of patients with tumors treated with CTL in MMS of 339 tumors, recording patient demographics, tumor characteristics, MMS stages for clearance, repairs, complications, and follow-up...
May 17, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29770463/a-first-for-dermatopathology-and-pathology-in-general-appropriate-use-criteria-in-dermatopathology-from-the-american-society-of-dermatopathology
#2
Adam I Rubin, Michael Hitchcock
In this issue of the Journal of Cutaneous Pathology(1), the ASDP Appropriate Use Criteria (AUC) Task Force releases a landmark series of recommendations on AUC from the American Society of Dermatopathology. This is the first set of AUC in dermatopathology and, indeed, in pathology overall. These recommendations were developed as part of the work of the ASDP AUC Task Force, created in 2015. This publication provides strong, evidence-based recommendations that will improve the delivery and utilization of care for our patients, just as AUC for Mohs surgery have elevated the discourse on that procedure for the benefit of patients and society as a whole(2)...
May 17, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29770284/solitary-palmar-keratoacanthoma-case-report
#3
Raghavendra L Girijala, Young Kwak, David Wright, Leonard H Goldberg
Keratoacanthoma (KA) is a squamous neoplasm exhibiting a triphasic growth pattern involving rapid growth, stabilization, and eventual spontaneous resolution. Historically, keratoacanthomas were thought to originate on hair-bearing skin or sun-exposed surfaces. However, recent reports demonstrate that they can occur on the mucous membranes, subungual regions, and palms and soles. We report a 74-year-old man who developed a KA on the left palmar surface after minor trauma, for which he underwent Mohs' micrographic surgery...
March 15, 2018: Curēus
https://www.readbyqxmd.com/read/29765274/review-of-eyelid-reconstruction-techniques-after-mohs-surgery
#4
REVIEW
Sagar Yatin Patel, Kamel Itani
Mohs micrographic surgery achieves high cure rates while preserving healthy tissue making it the optimal treatment for skin cancer. The goals of eyelid reconstruction after Mohs surgery include restoring eyelid structure and function while attaining acceptable aesthetic results. Given the variety of eyelid defects encountered after Mohs surgery, a thorough understanding of the complex eyelid anatomy as well as an in-depth knowledge of the numerous reconstructive techniques available are required to accomplish these reconstructive goals...
May 2018: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/29765270/simplifying-lip-reconstruction-an-algorithmic-approach
#5
REVIEW
Kyle J Sanniec, Jourdan A Carboy, James F Thornton
The authors provide an overview of lip reconstruction after Mohs surgery based on the senior author's practice. Lip reconstruction offers unique challenges to preserve not only lip function but also aesthetics. Lip reconstruction must take into consideration the three anatomical layers that comprise the lip and defects that involve the mucosa, the muscle, the skin or more than one layer will help determine the modality of repair. The authors offer an algorithm based on defect location, tissue involvement, and severity of defect to simplify an often complex decision-making process...
May 2018: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/29765269/mohs-micrographic-surgery-development-technique-and-applications-in-cutaneous-malignancies
#6
REVIEW
Eillen Luisa A Chen, Divya Srivastava, Rajiv I Nijhawan
Mohs micrographic surgery (MMS) is a specialized technique for treating skin malignancies that offers the highest cure rate by allowing histological evaluation of the entire peripheral and deep margins. MMS also maximally preserves as much uninvolved, normal adjacent tissue as possible, allowing for the best cosmetic and functional outcomes. When used for appropriate indications, this technique is also more cost-effective than other treatment modalities. In this article, the authors will discuss the development of MMS, the steps involved in this procedure, and the indications for this technique...
May 2018: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/29763492/perianal-extramammary-paget-disease-treated-with-topical-imiquimod-and-oral-cimetidine
#7
Jayla Gray, Arielle Gray, James Swan, Joshua Eberhardt, Kumaran Mudaliar, Rebecca Tung
Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma. The current mainstay of treatment is wide local excision. We present the case of a 56-year-old woman with perianal EMPD that recurred 4 years after initial treatment with wide local excision with Mohs micrographic surgery tissue processing of marginal tissue. Upon recurrence with anal canal involvement, the patient was treated with a 16-week combination course of topical imiquimod and oral cimetidine. There is growing evidence to support both the use of topical imiquimod for the treatment of EMPD as well as the antioncogenic effects of oral cimetidine...
April 2018: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29763491/penile-squamous-cell-carcinoma-with-urethral-extension-treated-with-mohs-micrographic-surgery
#8
Ardeshir E Nadimi, Ali Hendi
Penile squamous cell carcinoma (SCC) with considerable urethral extension is uncommon and difficult to manage. It often is resistant to less invasive and nonsurgical treatments and frequently results in partial or total penectomy, which can lead to cosmetic disfigurement, functional issues, and psychological distress. We report a case of penile SCC in situ with considerable urethral extension with a focus of cells suspicious for moderately well-differentiated and invasive SCC that was treated with Mohs micrographic surgery (MMS)...
April 2018: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29746431/impact-of-mohs-micrographic-surgery-on-tumor-staging-of-cutaneous-squamous-cell-carcinoma-a-comparison-of-the-7th-and-8th-editions-of-the-american-joint-committee-on-cancer-guidelines
#9
Michael A Montuno, Brandon Brown, Sailesh Konda, Kiran Motaparthi
BACKGROUND: Based on current AJCC-7 guidelines for staging cutaneous squamous cell carcinoma (cSCC), patients with T2 tumor staging represent a prognostically heterogeneous group. The new AJCC-8 guidelines seek to provide improved stratification by inclusion of independent risk factors in the T3 category. These features may be identified in tissue stages during Mohs micrographic surgery (MMS). Thus, low-risk cSCC may be upstaged after MMS, impacting prognosis, additional evaluation, and adjuvant nonsurgical treatment...
May 4, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29742183/facial-basal-cell-carcinoma-in-patients-younger-than-40
#10
Ardeshir Edward Nadimi, Yizhao Zhou, Jaeil Ahn, Ali Hendi
INTRODUCTION: The incidence of basal cell carcinoma in the population younger than 40 years is rising, and a majority of basal cell carcinomas occur on the head and neck. Our objective was to determine whether basal cell carcinomas in the population younger than 40 years occur more frequently at the forehead and its subunits (forehead proper, temple, suprabrow, and glabella). METHODS: We performed a retrospective case review of 4,337 basal cell carcinomas in 3,223 patients treated with Mohs micrographic surgery...
May 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29742181/a-retrospective-analysis-of-complication-rates-in-mohs-micrographic-surgery-patients-with-clinically-large-tumors-and-tumors-with-aggressive-subclinical-extension
#11
Natasha Cowan, Alina Goldenberg, Pallavi Basu, Robert Eilers, Jennifer Hau, Shang I Brian Jiang
BACKGROUND: Clinically large cutaneous tumors and those with aggressive subclinical extension (ASE) often require wider margins and increased operative time during Mohs micrographic surgery (MMS). Our goal is to improve dermatologic surgeons' counseling information on complication risks for aggressive tumors. OBJECTIVE: To examine the incidence of postoperative complications in MMS patients, with a focus on differences between aggressive and non-aggressive tumors...
May 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29742179/demographic-and-tumor-characteristics-of-patients-younger-than-50-years-with-nonmelanoma-skin-cancer-referred-for-mohs-micrographic-surgery
#12
Nicola A Quatrano, Euphemia W Mu, David E Orbuch, Adele Haimovic, Roy G Geronemus, Jeremy A Brauer
BACKGROUND: An increase in nonmelanoma skin cancer (NMSC) in younger patients has been reported. Many are treated with Mohs micrographic surgery (MMS). OBJECTIVE: Investigate patient and tumor characteristics in patients less than 50 years undergoing MMS for NMSC at a large, referral-based practice. METHODS & MATERIALS: Retrospective chart review of 1,332 tumors occurring in 1,018 consecutive patients over a five-year period. RESULTS: 81...
May 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29728289/bilateral-interdigitated-pacman-flap-for-round-and-oval-facial-defects
#13
Sang-Ha Oh, Hyeokjae Kwon, Sun Je Kim, Hyunwoo Kyung, Young Joon Seo, Dae Hyun Lew, Seung Han Song
BACKGROUND: Skin texture and color are important considerations during the reconstruction of facial defects, and anatomical borders should be preserved. Therefore, a local flap is a better option. In these cases, the authors repaired facial defects using a bilateral interdigitated VY flap. OBJECTIVE: We aim to present a modified bilateral Pacman flap technique for the reconstruction of round and oval facial defects. MATERIALS AND METHODS: We performed a retrospective chart review of 25 patients (26 cases) who underwent bilateral interdigitated Pacman flap repair of round and oval facial defects after Mohs surgery for skin cancer from January 2012 to December 2017...
April 12, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29727201/appropriate-use-criteria-for-basal-cell-carcinoma-mohs-surgery-at-a-single-center-in-the-face-of-high-burden-skin-cancer-a-retrospective-cohort-study
#14
Bruno de Carvalho Fantini, Roberto Bueno Filho, Fernando Chahud, Cacilda da Silva Souza
BACKGROUND: Mohs micrographic surgery (MMS) promotes high cure rates, but accessibility to MMS is limited in distinctive realities and countries. OBJECTIVE: We sought to verify applicable criteria for MMS indication and prioritization regarding basal cell carcinoma (BCC) in the face of various limitations. METHODS: We analyzed MMS-excised BBC, without patient exclusion, through a retrospective cohort study at a single university center. RESULTS: MMS was performed in 101 BCCs, average size = 5...
May 4, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29726112/simple-3-criteria-based-ex-vivo-confocal-diagnosis-of-basal-cell-carcinoma
#15
Daniela Hartmann, Sebastian Krammer, Mario Raphael Bachmann, Leonie Mathemeier, Thomas Ruzicka, Tanja von Braunmühl
BACKGROUND: Fast and simple microscopic evaluation of basal cell carcinoma (BCC) together with its subtype determination would accelerate diagnostic and therapeutic procedures in dermatology including Mohs surgery. OBJECTIVES: Assessing whether simplified 3-criteria-based ex-vivo confocal microscopic (CM) examination can reliably predict BCC diagnosis and subtype. Analyzing interobserver agreement between expert and novice examiner. METHODS: CM images of 235 skin samples from 150 patients were prospectively evaluated by two blinded examiners for the presence of 3 predefined BCC criteria namely presence of tumor mass, peripheral palisading and clefting...
May 3, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29725859/surgical-treatment-for-extramammary-paget-s-disease
#16
REVIEW
Uwe Wollina, Alberto Goldman, Andrzej Bieneck, Mohamed Badawy Abdel-Naser, Sven Petersen
Extramammary Paget's disease (EMPD) is a rare, slow growing non-melanoma skin cancer.Diagnosis is often significantly delayed, since clinical presentation may resemble common benign dermatoses. Treatment is characterized by high recurrence rates. This is in part due to ill-defined margins and by frequent development of satellites. Improvement of outcome needs a better preoperative planning with fluorescence diagnostics or scouting biopsies. Mohs micrographic surgery has some advantages for patients, such as reduced relapse rates and prolonged relapse-free survival...
May 3, 2018: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29706031/mohs-micrographic-surgery-for-nail-unit-tumors-an-update-and-a-critical-review-of-the-literature
#17
REVIEW
M Lambertini, B M Piraccini, P A Fanti, E Dika
Mohs micrographic surgery (MMS) is a good treatment option for epithelial neoplasms, especially when localized in areas where tissue conservation is crucial, such as the nail unit (NU). MMS is a method of radical excision offering high cure rates due to the margin control and functional preservation. Our aim is to provide a review on the use of MMS for the treatment of the most common nail tumors. We revised the current literature on the use of MMS to treat malignant neoplasms (Bowen's disease, squamous cell carcinoma, melanoma, basal cell carcinoma, keratoacanthoma, carcinoma cuniculatum) and benign neoplasms (onychomatricoma and glomus tumor)...
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29701617/commentary-on-bupivacaine-as-an-adjunct-to-lidocaine-in-mohs-micrographic-surgery
#18
M Laurin Council, George J Hruza
No abstract text is available yet for this article.
May 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29696467/ocular-sebaceous-gland-carcinoma-an-update-of-the-literature
#19
REVIEW
Maria Vittoria Cicinelli, Swathi Kaliki
PURPOSE: To review and summarize the newest update on ocular sebaceous gland carcinoma (SGC) focusing on diagnosis and treatment. METHODS: A PubMed search was carried out using the terms "Sebaceous Carcinoma", "Meibomian Gland Carcinoma", "Sebaceous Cell Carcinoma", and "Sebaceous Gland Carcinoma". All studies published in English up to October 2017 were included in this review. RESULTS: Globally, the overall incidence of SGC is increasing making it the third most common eyelid malignancy after basal cell carcinoma (BCC) and squamous cell carcinoma...
April 25, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29687064/facial-pilomatrix-carcinomas-treated-with-mohs-micrographic-surgery
#20
Lin Xing, Sean A Marzolf, Travis Vandergriff, Rajiv I Nijhawan
No abstract text is available yet for this article.
April 2018: JAAD Case Reports
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