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https://www.readbyqxmd.com/read/28721025/antibacterial-effect-of-silver-nanoparticles-in-pseudomonas-aeruginosa
#1
R Salomoni, P Léo, A F Montemor, B G Rinaldi, Mfa Rodrigues
Pseudomonas aeruginosa has great intrinsic antimicrobial resistance limiting the number of effective antibiotics. Thus, other antimicrobial agents such as silver nanoparticles (AgNPs) are considered potential agents to help manage and prevent infections. AgNPs can be used in several applications against bacteria resistant to common antibiotics or even multi-resistant bacteria such as P. aeruginosa. This study assessed the antimicrobial activity of commercial 10 nm AgNPs on two hospital strains of P. aeruginosa resistant to a large number of antibiotics and a reference strain from a culture collection...
2017: Nanotechnology, Science and Applications
https://www.readbyqxmd.com/read/28652733/in-vitro-studies-of-nanosilver-doped-titanium-implants-for-oral-and-maxillofacial-surgery
#2
Rafał Pokrowiecki, Tomasz Zaręba, Barbara Szaraniec, Krzysztof Pałka, Agnieszka Mielczarek, Elżbieta Menaszek, Stefan Tyski
The addition of an antibacterial agent to dental implants may provide the opportunity to decrease the percentage of implant failures due to peri-implantitis. For this purpose, in this study, the potential efficacy of nanosilver-doped titanium biomaterials was determined. Titanium disks were incorporated with silver nanoparticles over different time periods by Tollens reaction, which is considered to be an eco-friendly, cheap, and easy-to-perform method. The surface roughness, wettability, and silver release profile of each disc were measured...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28650591/the-silver-lining-towards-the-responsible-and-limited-usage-of-silver
#3
REVIEW
Kshipra Naik, Meenal Kowshik
Silver has attracted a lot of attention as a powerful, broad spectrum and natural antimicrobial agent since the ancient times because of its non-toxic nature to the human body at low concentrations. It has been used in treatment of various infections and ulcers, storage of water, and prevention of bacterial growth on the surfaces and within materials. However there are numerous medical and health benefits of colloidal or nano silver apart from its microbicidal ability which as yet have not been fully embraced by the medical community...
June 26, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28646569/nanosilver-particles-increase-follicular-atresia-correlation-with-oxidative-stress-and-aromatization
#4
Masumeh Mirzaei, Mazdak Razi, Rajabali Sadrkhanlou
Present study was performed in order to update the possible mechanism(s), involving in nanosilver particles (NSPs)-induced detrimental impacts in ovarian tissue. For this purpose, 24 mature female rats were divided into control and 0.5, 1, 5 mg/kg NSPs-received groups (intraperitoneally, for 35 days). Follicular growth and atresia, ovarian total antioxidant capacity (TAC), malondialdehyde (MDA), superoxide dismutase (SOD) contents, serum estrogen (E2 ) level and macrophages infiltration were investigated. Moreover, ovarian angiogenesis, cellular mRNA damage and cytochrome aromatase CYP19 expression were analyzed...
June 24, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28643002/genotoxicity-testing-of-different-surface-functionalized-sio2-zro2-and-silver-nanomaterials-in-3d-human-bronchial-models
#5
Andrea Haase, Nils Dommershausen, Markus Schulz, Robert Landsiedel, Philipp Reichardt, Benjamin-Christoph Krause, Jutta Tentschert, Andreas Luch
Inhalation is considered a critical uptake route for NMs, demanding for sound toxicity testing using relevant test systems. This study investigates cytotoxicity and genotoxicity in EpiAirway™ 3D human bronchial models using 16 well-characterized NMs, including surface-functionalized 15 nm SiO2 (4 variants), 10 nm ZrO2 (4), and nanosilver (3), ZnO NM-110, TiO2 NM-105, BaSO4 NM-220, and two AlOOH NMs. Cytotoxicity was assessed by LDH and ATP assays and genotoxicity by the alkaline comet assay. For 9 NMs, uptake was investigated using inductively coupled plasma-mass spectrometry (ICP-MS)...
June 22, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28627324/preparation-characterization-and-in-vitro-cytotoxicity-of-chitosan-hydrogels-containing-silver-nanoparticles
#6
Bożena Tyliszczak, Anna Drabczyk, Sonia Kudłacik-Kramarczyk, Agnieszka Sobczak-Kupiec
Hydrogels, chitosan as well as silver nanoparticles become in recent years materials characterized by a great interest. In present paper hydrogel based on chitosan and containing mention type of nano-sized particles have been synthesized by means of photopolymerization. Sorption capacity in selected liquids as well as behavior in simulated body fluid (such as Ringer's liquid) have been determined. Particularly attention was paid to the studies on toxicity of the hydrogels in relation to the epidermal cells as well as on their impact on growth of selected strain of bacteria (Escherichia coli)...
June 17, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28623661/graphene-nanolayers-as-a-new-method-for-bacterial-biofilm-prevention-preliminary-results
#7
Łucja Dybowska-Sarapuk, Andrzej Kotela, Jakub Krzemiński, Marta Wróblewska, Halina Marchel, Magdalena Romaniec, Paweł Łęgosz, Małgorzata Jakubowska
Biofilms are microbial communities of surface-attached cells embedded in a self-produced extracellular matrix. They have been found to play a role in a wide variety of infections, including catheter-related urinary tract and bloodstream infections, and, therefore remain a significant source of morbidity and mortality among the world's population. Recently, much attention has been devoted to the prevention of biofilm formation on implant surfaces. Nanomaterials such as graphene, characterized by antibacterial activity and low toxicity to human cells, are promising candidates for biomedical applications...
June 16, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28596004/synthesis-of-dextrin-stabilized-colloidal-silver-nanoparticles-and-their-application-as-modifiers-of-cement-mortar
#8
Emilia Konował, Marta Sybis, Anna Modrzejewska-Sikorska, Grzegorz Milczarek
Various commercial dextrins were used as reducing and stabilizing agents for a novel one-step synthesis of silver nanoparticles from ammonia complexes of silver ions. As a result, stable colloids of silver were formed during the reaction with the particle size being the function of the dextrin type. The obtained colloids were characterized by UV-vis spectrophotometry, size distribution (using Non-Invasive Backscatter optics) and transmission electron microscopy (TEM). The achieved results clearly indicate the possibility of low-cost production of large quantities of colloidal silver nanoparticles using materials derived from renewable sources...
June 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28589745/green-synthesis-of-tea-ag-nanocomposite-hydrogels-via-mint-leaf-extraction-for-effective-antibacterial-activity
#9
Tippabattini Jayaramudu, Kokkarachedu Varaprasad, Gownolla Malegowd Raghavendra, E R Sadiku, Konduru Mohana Raju
In this report, we investigated the swelling behavior and antibacterial property of nanosilver composite hydrogels made from tea with polyacrylamide via a free-radical polymerization and green process technique. This is probably for the first time; tea-based nano silver composite hydrogels were developed. The composite hydrogels comprise of embedded nano silver particles in the tea hydrogel matrix via a green process with mint leaf extract. The size of the nano silver particles in the hydrogel matrix was found to be < 10 nm...
June 7, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28568508/cytotoxicity-and-genotoxicity-of-nanosilver-in-stable-gadd45%C3%AE-promoter-driven-luciferase-reporter-hepg2-and-a549-cells
#10
Bizhong Che, Qiulin Luo, Bingzhong Zhai, Guoqiang Fan, Zhiyong Liu, Kaiming Cheng, Lili Xin
OBJECTIVES: The intense commercial application of silver nanoparticles (AgNPs) has been raising concerns about their potential adverse health effects to human. This study aimed to explore the potency of AgNPs to induce GADD45α gene, an important stress sensor, and its relationships with the cytotoxicity and genotoxicity elicited by AgNPs. METHODS: Two established HepG2 and A549 cell lines containing the GADD45α promoter-driven luciferase reporter were treated with increasing concentrations of AgNPs for 48 hours...
June 1, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28537069/life-cycle-assessment-and-release-studies-for-15-nanosilver-enabled-consumer-products-investigating-hotspots-and-patterns-of-contribution
#11
Leila Pourzahedi, Marina Vance, Matthew J Eckelman
Increasing use of silver nanoparticles (AgNPs) in consumer products as antimicrobial agents has prompted extensive research toward the evaluation of their potential release to the environment and subsequent ecotoxicity to aquatic organisms. It has also been shown that AgNPs can pose significant burdens to the environment from life cycle emissions associated with their production, but these impacts must be considered in the context of actual products that contain nanosilver. Here, a cradle-to-gate life cycle assessment for the production of 15 different AgNP-enabled consumer products was performed, coupled with release studies of those same products, thus providing a consistent analytical platform for investigation of potential nanosilver impacts across a range of product types and concentrations...
June 9, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28533681/synergistic-bactericidal-activity-of-chlorhexidine-loaded-silver-decorated-mesoporous-silica-nanoparticles
#12
Meng-Meng Lu, Qiu-Jing Wang, Zhi-Min Chang, Zheng Wang, Xiao Zheng, Dan Shao, Wen-Fei Dong, Yan-Min Zhou
Combination of chlorhexidine (CHX) and silver ions could engender synergistic bactericidal effect and improve the bactericidal efficacy. It is highly desired to develop an efficient carrier for the antiseptics codelivery targeting infection foci with acidic microenvironment. In this work, monodisperse mesoporous silica nanoparticle (MSN) nanospheres were successfully developed as an ideal carrier for CHX and nanosilver codelivery through a facile and environmentally friendly method. The CHX-loaded, silver-decorated mesoporous silica nanoparticles (Ag-MSNs@CHX) exhibited a pH-responsive release manner of CHX and silver ions simultaneously, leading to synergistically antibacterial effect against both gram-positive Staphylococcus aureus and gram-negative Escherichia coli...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28531948/an-alternative-approach-to-risk-rank-chemicals-on-the-threat-they-pose-to-the-aquatic-environment
#13
Andrew C Johnson, Rachel L Donnachie, John P Sumpter, Monika D Jürgens, Claudia Moeckel, M Gloria Pereira
This work presents a new and unbiased method of risk ranking chemicals based on the threat they pose to the aquatic environment. The study ranked 12 metals, 23 pesticides, 11 other persistent organic pollutants (POPs), 13 pharmaceuticals, 10 surfactants and similar compounds and 2 nanoparticles (total of 71) of concern against one another by comparing their median UK river water and median ecotoxicity effect concentrations. To complement this, by giving an assessment on potential wildlife impacts, risk ranking was also carried out by comparing the lowest 10th percentile of the effects data with the highest 90th percentile of the exposure data...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28530183/effects-of-heat-treatment-on-sound-absorption-coefficients-in-nanosilver-impregnated-and-normal-solid-woods
#14
Ayoub Esmailpour, Hamid Reza Taghiyari, Habib Zolfaghari
Effects of impregnation with silver nano-suspension as well as heat-treatment on sound absorption coefficients (AC) were studied in tangential direction of five different solid woods based on their importance. AC was measured at two frequencies of 250 and 500 Hz. A 400 ppm nanosuspension was used for the impregnation; silver nanoparticles had a size range of 30-80 nm. Based on the obtained results, the species reacted significantly different in absorbing sound at the two frequencies. Impregnation with nano-suspension substantially decreased AC at the lower frequency of 250 Hz; it did not show any particular trend when AC was measured at the frequency of 500 Hz...
June 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28512478/subcutaneous-reaction-of-rat-tissues-to-nanosilver-coated-gutta-percha
#15
Mohammad Ali Mozayeni, Omid Dianat, Shahin Tahvildari, Maryam Mozayani, Payam Paymanpour
INTRODUCTION: Gutta-percha (GP), is a neutral and non-toxic material. The aim of this animal study was to compare the biocompatibility of nanosilver coated GP (NS-GP) with conventional GP in subcutaneous tissues in a rat model. METHODS AND MATERIALS: Conventional GP and NS-GP were subcutaneously implanted in the backs of 20 male Wistar rats (n=10). A control animal was assigned for each trial period. Ten animals were sacrificed after 7 and 30 days and light microscopic evaluation of tissue reaction to NS-GP (n=20) and conventional GP (n=20) was accomplished...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28473893/effects-of-silver-nanoparticles-on-staphylococcus-aureus-contaminated-open-wounds-healing-in-mice-an-experimental-study
#16
Masood Adibhesami, Malahat Ahmadi, Amir Abbas Farshid, Farshid Sarrafzadeh-Rezaei, Bahram Dalir-Naghadeh
The microorganisms have been noted as the main cause of delayed wound healing. The most common pathogen causing the wound infections is Staphylococcus aureus. Silver nanoparticles (AgNPs) show ample antibacterial activities. In the present study, the effect of AgNPs on mouse wounds inoculated with S. aureus was investigated. Sixty male mice (20 to 30 g) were anesthetized, full-thickness skin wounds were made on their back and then the bacterial suspension was added to each wound bed. Treatments were administered on wound bed topically including gentamicin (8 mg kg(-1)), AgNPs (0...
2017: Veterinary Research Forum
https://www.readbyqxmd.com/read/28470622/green-synthesis-and-characterization-of-ag-nanoparticles-from-mangifera-indica-leaves-for-dental-restoration-and-antibacterial-applications
#17
Dola Sundeep, T Vijaya Kumar, P S Subba Rao, R V S S N Ravikumar, A Gopala Krishna
Green synthesis has gained a wide recognition as clean synthesis technique in the recent years. In the present investigation, silver nanoparticles were prepared by a novel green synthesis technique using Mangifera indica (Mango leaves) and found to be successfully used in dental applications. The prepared samples were spectroscopically characterized by XRD, PSA, SEM with EDS, and UV-Vis spectroscopy. The crystalline size and lattice strain were analyzed from the XRD data which were counter-verified by W-H plots and particle size analyzer...
May 2017: Progress in biomaterials
https://www.readbyqxmd.com/read/28458540/surface-ligand-controls-silver-ion-release-of-nanosilver-and-its-antibacterial-activity-against-escherichia-coli
#18
Yan-Min Long, Li-Gang Hu, Xue-Ting Yan, Xing-Chen Zhao, Qun-Fang Zhou, Yong Cai, Gui-Bin Jiang
Understanding the mechanism of nanosilver-dependent antibacterial activity against microorganisms helps optimize the design and usage of the related nanomaterials. In this study, we prepared four kinds of 10 nm-sized silver nanoparticles (AgNPs) with dictated surface chemistry by capping different ligands, including citrate, mercaptopropionic acid, mercaptohexanoic acid, and mercaptopropionic sulfonic acid. Their surface-dependent chemistry and antibacterial activities were investigated. Owing to the weak bond to surface Ag, short carbon chain, and low silver ion attraction, citrate-coated AgNPs caused the highest silver ion release and the strongest antibacterial activity against Escherichia coli, when compared to the other tested AgNPs...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28458539/in-situ-green-synthesis-of-antimicrobial-carboxymethyl-chitosan-nanosilver-hybrids-with-controlled-silver-release
#19
Siqi Huang, Zhiming Yu, Yang Zhang, Chusheng Qi, Shifeng Zhang
In order to fabricate antimicrobial carboxymethyl chitosan-nanosilver (CMC-Ag) hybrids with controlled silver release, this study demonstrated comparable formation via three synthetic protocols: 1) carboxymethyl chitosan (CMC) and glucose (adding glucose after AgNO3), 2) CMC and glucose (adding glucose before AgNO3), and 3) CMC only. Under principles of green chemistry, the synthesis was conducted in an aqueous medium exposed to microwave irradiation for 10 minutes with nontoxic chemicals. The structure and formation mechanisms of the three CMC-Ag hybrids were explored using X-ray diffraction, ultraviolet-visible spectroscopy, transmission electron microscopy, and Fourier-transform infrared analyses...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28419542/effect-of-nanosilver-on-metabolism-in-rainbow-trout-oncorhynchus-mykiss-an-investigation-using-different-respirometric-approaches
#20
Laura Murray, Michael D Rennie, Jon C Svendsen, Eva C Enders
Nanosilver (nAg) has been incorporated into many consumer products, including clothing and washing machines, because of its antimicrobial properties. Consequently, the potential for its release into aquatic environments is of significant concern. Documented toxic effects on fish include altered gene expression, gill damage, and impaired gas exchange, as well as mortality at high nAg concentrations. The present study reports the effects of nAg on the metabolism of rainbow trout (Oncorhynchus mykiss). Fish were exposed to environmentally relevant concentrations (0...
April 17, 2017: Environmental Toxicology and Chemistry
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