keyword
MENU ▼
Read by QxMD icon Read
search

Duration of antibiotic therapy

keyword
https://www.readbyqxmd.com/read/28650745/longer-duration-antimicrobial-therapy-does-not-prevent-treatment-failure-in-high-risk-patients-with-complicated-intra-abdominal-infections
#1
Taryn E Hassinger, Christopher A Guidry, Ori D Rotstein, Therese M Duane, Heather L Evans, Charles H Cook, Patrick J O'neill, John E Mazuski, Reza Askari, Lena M Napolitano, Nicholas Namias, Preston R Miller, E Patchen Dellinger, Raul Coimbra, Christine S Cocanour, Kaysie L Banton, Joseph Cuschieri, Kimberley Popovsky, Robert G Sawyer
BACKGROUND: Recent studies have suggested the length of treatment of intra-abdominal infections (IAIs) can be shortened without detrimental effects on patient outcomes. However, data from high-risk patient populations are lacking. We hypothesized that patients at high risk for treatment failure will benefit from a longer course of antimicrobial therapy. METHODS: Patients enrolled in the Study to Optimize Peritoneal Infection Therapy (STOP-IT) trial were evaluated retrospectively to identify risk factors associated with treatment failure, which was defined as the composite outcome of recurrent IAI, surgical site infection, or death...
June 26, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28649083/report-prevalence-of-hospital-acquired-burkholderia-cepacia-infection-and-its-antimicrobial-susceptibility-in-a-chinese-hospital
#2
Jinju Duan, Jianbang Kang, Ting Han, Yuqin Ma, Qian Guo, Yan Song, Qiang Zhao, Yan Yang, Ruiqin Zhang
This study aimed to investigate antimicrobial susceptibility of hospital acquired Burkholderia cepacia infection in Shanxi (China) during August 2009 and December 2012. To characterize an emerging nocosomial infection. The medical records of 112 patients that were tested positive for B. cepacia were retrospectively analyzed. The K-B disk diffusion method was used to determine the drug susceptibility of the isolated strains. A hundred and fifty strains of B. cepacia were isolated from 112 patients. The sensitivity rates of B...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28647716/bilateral-recurrent-pyosalpinx-in-a-sexually-inactive-12-year-old-girl-secondary-to-rare-variant-of-mullerian-duct-anomaly
#3
Tareq Maraqa, Mohamed Mohamed, Daniel Coffey, Gul R Sachwani-Daswani, Crystal Alvarez, Leo Mercer
Pyosalpinx is a severe sequel of chronic pelvic inflammatory disease, whereby the fallopian tubes become filled with pus.(1 2) Pyosalpinx often affects sexually active women and rarely is seen in celibate adolescent girls.(3) We report a case of a 12-year-old girl with no prior sexual history who presented to our emergency department with complaints of severe right lower quadrant pain of 1-day duration. Ultrasonography and CT scan of the abdomen and pelvis revealed free fluid collections in the pelvis without visualisation of the appendix...
June 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28642109/neoaortic-xenoprosthetic-grafts-for-treatment-of-mycotic-aneurysms-and-infected-aortic-grafts
#4
C Anibueze, V Sankaran, U Sadat, K Tan, Y G Wilson, R E Brightwell, M S Delbridge, P W Stather
OBJECTIVE: There is no international consensus regarding the optimum management of infected aortae (mycotic aneurysms, infected aortic grafts). Neoaortoiliac reconstruction has advantages over extra anatomical bypass grafting; however use of autologous vein is associated with venous hypertension and compartment syndrome, alternatively cadaveric homografts are associated with high rates of perianastomotic haemorrhage, limb occlusion and pseudoaneurysm. Arterial repair using xenoprosthetic patches is associated with lower infection rates compared to the use of prosthetic material...
June 19, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28631985/effect-of-a-standardized-protocol-of-antibiotic-therapy-on-surgical-site-infection-after-laparoscopic-surgery-for-complicated-appendicitis
#5
Hyoung-Chul Park, Min Jeong Kim, Bong Hwa Lee
BACKGROUND: Although it is accepted that complicated appendicitis requires antibiotic therapy to prevent post-operative surgical infections, consensus protocols on the duration and regimens of treatment are not well established. This study aimed to compare the outcome of post-operative infectious complications in patients receiving old non-standardized and new standard antibiotic protocols, involving either 5 or 10 days of treatment, respectively. METHODS: We enrolled 1,343 patients who underwent laparoscopic surgery for complicated appendicitis between January 2009 and December 2014...
June 20, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28631307/interventions-for-the-prevention-of-recurrent-erysipelas-and-cellulitis
#6
REVIEW
Adam Dalal, Marina Eskin-Schwartz, Daniel Mimouni, Sujoy Ray, Walford Days, Emmilia Hodak, Leonard Leibovici, Mical Paul
BACKGROUND: Erysipelas and cellulitis (hereafter referred to as 'cellulitis') are common bacterial skin infections usually affecting the lower extremities. Despite their burden of morbidity, the evidence for different prevention strategies is unclear. OBJECTIVES: To assess the beneficial and adverse effects of antibiotic prophylaxis or other prophylactic interventions for the prevention of recurrent episodes of cellulitis in adults aged over 16. SEARCH METHODS: We searched the following databases up to June 2016: the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, and LILACS...
June 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28628930/-rational-use-of-antibiotics-data-form-a-survey-from-2014-within-the-mrdo-network-compared-to-nationwide-data-from-2009
#7
Luba Lendowski, Peter Walger, Christoph Hoeser, Martin Exner, Claudia Roesing, Steffen Engelhart
Introduction To combat multi-resistant gram-negative bacteria as the cause of life-threatening infections, antibiotic stewardship activities are of great importance. Objective To detect weaknesses when prescribing antibiotics in hospitals and compare the situation between 2009 and 2014. Methods In 2014, a questionnaire was sent to all 380 physicians employed in 7 hospitals. Primary, secondary and tertiary care hospitals were included. Investigated were: demographic data, position, certified specialization, presence of antibiotic prescription rules and behavior to follow them...
June 19, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28627430/changes-in-eosinophil-count-during-bacterial-infection-revisiting-an-old-marker-to-assess-the-efficacy-of-antimicrobial-therapy
#8
B Davido, S Makhloufi, M Matt, R Calin, O Senard, C Perronne, A Dinh, J Salomon
INTRODUCTION: Eosinopenia as a criterion of sepsis has been the subject of debate for decades. Different authors have proposed different cut-off values. METHODS: A prospective study was conducted from February to August 2016. Hospitalized adults suffering from a bacterial infection with eosinopenia, defined as an eosinophil count <100/mm(3), were included. Patients were divided into two groups according to the first day of effective antimicrobial therapy. They were observed for 5days in order to evaluate whether recovery from eosinopenia was predictive of an appropriate antibiotic regimen...
June 13, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28626858/antibiotics-for-acute-bronchitis
#9
REVIEW
Susan M Smith, Tom Fahey, John Smucny, Lorne A Becker
BACKGROUND: The benefits and risks of antibiotics for acute bronchitis remain unclear despite it being one of the most common illnesses seen in primary care. OBJECTIVES: To assess the effects of antibiotics in improving outcomes and to assess adverse effects of antibiotic therapy for people with a clinical diagnosis of acute bronchitis. SEARCH METHODS: We searched CENTRAL 2016, Issue 11 (accessed 13 January 2017), MEDLINE (1966 to January week 1, 2017), Embase (1974 to 13 January 2017), and LILACS (1982 to 13 January 2017)...
June 19, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28623538/clinically-promising-biomarkers-in-cystic-fibrosis-pulmonary-exacerbations
#10
REVIEW
L Keith Scott, Robert Toner
Cystic fibrosis is a complex genetic disease hallmarked by repetitive infectious exacerbations that leads to destruction of airway architecture, acute on chronic inflammatory changes, and deterioration in lung function. Predicting an exacerbation may help preempt some of these changes by the initiation of swift antibiotic and anti-inflammatory therapy. A search for biomarkers that could predict exacerbations or help guide duration of antibiotic therapy is being aggressively sought. In this review, we discuss the most recent and promising biomarkers that hopefully will assist in the future management of the CF patient...
June 16, 2017: Lung
https://www.readbyqxmd.com/read/28616060/early-recognition-of-methicillin-resistant-staphylococcus-aureus-surgical-site-infections-using-risk-and-protective-factors-identified-by-a-group-of-italian-surgeons-through-delphi-method
#11
G Sganga, C Tascini, E Sozio, S Colizza
BACKGROUND: Surgical site infections (SSIs) constitute a major clinical problem in terms of morbidity, mortality, duration of hospital stay, and overall costs. The bacterial pathogens implicated most frequently are Streptococcus pyogenes (S. pyogenes) and Staphylococcus aureus (S. aureus). The incidence of methicillin-resistant S. aureus (MRSA) SSIs is increasing significantly. Since these infections have a significant impact on hospital budgets and patients' health, their diagnosis must be anticipated and therapy improved...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28608525/antimicrobials-used-for-surgical-prophylaxis-by-equine-veterinary-practitioners-in-australia
#12
L Y Hardefeldt, G F Browning, K Thursky, J R Gilkerson, H Billman-Jacobe, M A Stevenson, K E Bailey
BACKGROUND: Antimicrobials are widely used in Australian veterinary practices, but no investigation into the classes of antimicrobials used or the appropriateness of use in horses has been conducted. OBJECTIVES: The aim of the study was to describe antimicrobial use for surgical prophylaxis in equine practice in Australia. STUDY DESIGN: Cross-sectional questionnaire survey. METHODS: An online questionnaire was used to document antimicrobial usage patterns...
June 13, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28607765/paediatric-bone-and-joint-infection
#13
REVIEW
Alexios D Iliadis, Manoj Ramachandran
Despite advances in understanding and management, paediatric osteoarticular infections continue to pose diagnostic difficulties for clinicians. Delays in diagnosis can lead to potentially devastating morbidity.No single investigation, including joint aspiration, is sufficiently reliable to diagnose conclusively paediatric bone and joint infection. Diagnosis should be based on a combination of clinical signs, imaging and laboratory investigations. Algorithms should supplement, and not replace, clinical decision making in all cases...
January 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28607552/procalcitonin-guided-antibiotics-after-surgery-for-peritonitis-a-randomized-controlled-study
#14
Juliette C Slieker, Steve Aellen, Philippe Eggimann, Valentine Guarnero, Markus Schäfer, Nicolas Demartines
BACKGROUND: Serum procalcitonin (PCT) is a useful biomarker to tailor the duration of antibiotics in respiratory infections. The objective of this study was to determine whether PCT levels could tailor postoperative antibiotic therapy in patients operated for peritonitis. METHOD: Patients with peritonitis were randomized postoperatively. The control group received antibiotics for a defined duration according to institutional guidelines. In the study group, antibiotics were stopped based on serum PCT levels...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28604792/characteristics-clinical-course-and-outcomes-of-homeless-and-non-homeless-patients-admitted-to-icu-a-retrospective-cohort-study
#15
Orla M Smith, Clarence Chant, Karen E A Burns, Maninder Kaur, Said Ashraf, Claudia C DosSantos, Stephen W Hwang, Jan O Friedrich
BACKGROUND: Little is known about homeless patients in intensive care units (ICUs). OBJECTIVES: To compare clinical characteristics, treatments, and outcomes of homeless to non-homeless patients admitted to four ICUs in a large inner-city academic hospital. METHODS: 63 randomly-selected homeless compared to 63 age-, sex-, and admitting-ICU-matched non-homeless patients. RESULTS: Compared to matched non-homeless, homeless patients (average age 48±12 years, 90% male, 87% admitted by ambulance, 56% mechanically ventilated, average APACHE II 17) had similar comorbidities and illness severity except for increased alcohol (70% vs 17%,p<0...
2017: PloS One
https://www.readbyqxmd.com/read/28604514/early-antibiotic-exposure-in-low-resource-settings-is-associated-with-increased-weight-in-the-first-two-years-of-life
#16
Elizabeth T Rogawski, James A Platts-Mills, Jessica C Seidman, Sushil John, Mustafa Mahfuz, Manjeswori Ulak, Sanjaya Shrestha, Sajid Bashir Soofi, Pablo Penataro Yori, Estomih Mduma, Erling Svensen, Tahmeed Ahmed, Aldo A M Lima, Zulfiqar Bhutta, Margaret Kosek, Dennis Lang, Michael Gottlieb, Anita Zaidi, Gagandeep Kang, Pascal Bessong, Eric R Houpt, Richard L Guerrant
OBJECTIVES: The potential growth-promoting effects of antibiotics are not well understood among undernourished children in environments with high pathogen exposure. We aimed to assess whether early antibiotic exposure duration and class were associated with growth to two years of age across 8 low-resource sites in the MAL-ED birth cohort study. METHODS: We followed 1,954 children twice per week from birth to two years to record maternally-reported antibiotic exposures and measure anthropometry monthly...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28603723/biomarker-guided-antibiotic-therapy-strengths-and-limitations
#17
REVIEW
David Nora, Jorge Salluh, Ignacio Martin-Loeches, Pedro Póvoa
Biomarkers as C-reactive protein (CRP) and procalcitonin (PCT) emerged as tools to help clinicians to diagnose infection and to properly initiate and define the duration of antibiotic therapy. Several randomized controlled trials, including adult critically ill patients, showed that PCT-guided antibiotic stewardship was repeatedly associated with a decrease in the duration of antibiotic therapy with no apparent harm. There are however some relevant limitations in these trials namely the low rate of compliance of PCT-guided algorithms, the high rate of exclusion (without including common clinical situations and pathogens) and the long duration of antibiotic therapy in control groups...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28601485/surgical-treatment-of-shoulder-infections-a-comparison-between-arthroscopy-and-arthrotomy
#18
Christoph Böhler, Alexander Pock, Wenzel Waldstein, Kevin Staats, Stephan E Puchner, Johannes Holinka, Reinhard Windhager
BACKGROUND: Management of bacterial shoulder infections includes antibiotic therapy and surgical joint decompression. Arthroscopy and open arthrotomy are recommended treatment options. Whether 1 of the 2 surgical options is superior remains unclear. The present study aimed (1) to compare the reinfection rates after arthroscopy and open arthrotomy and (2) to identify risk factors of reinfection after surgical intervention. MATERIALS AND METHODS: The data of 59 consecutive patients were available for final analysis...
June 7, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28599969/prolonged-antibiotic-treatment-for-infected-low-flow-vascular-malformations
#19
Katy M Wagner, Zerina Lokmic, Anthony J Penington
BACKGROUND: Infection in low flow malformations is difficult to diagnose and treat. Initial presentation can be followed by cycles of recurrent infection lasting several years. The optimal duration of antibiotic therapy to prevent recurrence of infection has not been established. METHODS: All cases of infection in low flow malformations at the Royal Children's Hospital over a ten-year period were reviewed. Clinical markers of infection and duration of initial antibiotic treatment were correlated with the development of recurrent episodes of infection...
May 27, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28596927/necrotizing-pseudomonas-aeruginosa-community-acquired-pneumonia-a-case-report-and-review-of-the-literature
#20
Satish Maharaj, Carmen Isache, Karan Seegobin, Simone Chang, Grant Nelson
Lung cavities are not typically associated with community-acquired pneumonia (CAP). CAP due to P. aeruginosa is rare and even less commonly causes necrotizing pneumonia. We report a case of P. aeruginosa CAP that progressed to necrotizing pneumonia and was eventually fatal. Procalcitonin (PCT) has been well investigated in guiding antibiotic therapy (especially CAP) in adults. In this case, PCT at presentation and sequentially was negative. We discuss this caveat and present hypotheses as to the sensitivity and specificity of PCT and C-reactive protein (CRP) in these patients...
2017: Case Reports in Infectious Diseases
keyword
keyword
24438
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"