Zhitong Jiang, Can Huang, Erliang Guo, Xiangbin Zhu, Na Li, Yu Huang, Peihe Wang, Hui Shan, Yuxin Yin, Hong Wang, Lei Huang, Zhen Han, Kunfu Ouyang, Lu Sun
As people age, their ability to resist injury and repair damage decreases significantly. Platelet-rich plasma (PRP) has demonstrated diverse therapeutic effects on tissue repair. However, the inconsistency of patient outcomes poses a challenge to the practical application of PRP in clinical practice. Furthermore, a comprehensive understanding of the specific impact of aging on PRP requires a systematic investigation. We derived PRP from 6 young volunteers and 6 elderly volunteers, respectively. Subsequently, 95% of high-abundance proteins were removed, followed by mass spectrometry analysis...
April 15, 2024: Journal of Proteome Research