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https://www.readbyqxmd.com/read/28342714/higher-uric-acid-serum-levels-are-associated-with-better-muscle-function-in-the-oldest-old-results-from-the-mugello-study
#1
R Molino-Lova, F Sofi, G Pasquini, F Vannetti, S Del Ry, C Vassalle, M Clerici, S Sorbi, C Macchi
BACKGROUND: Sarcopenia is the progressive loss of muscle mass and strength that occurs with advancing age and plays a pivotal role in the causal pathway leading to frailty, disability and, eventually, to death among older persons. As oxidative damage of muscle proteins has been shown to be a relevant contributory factor, in this study we hypothesized that uric acid (UA), a powerful endogenous antioxidant, might exert a protective effect on muscle function in the oldest old and we tested our hypothesis in a group of nonagenarians who participated in the Mugello Study...
March 22, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28340152/sarcopenia-and-relationships-between-muscle-mass-measured-glomerular-filtration-rate-and-physical-function-in-patients-with-chronic-kidney-disease-stages-3-5
#2
Yunan Zhou, Matthias Hellberg, Philippa Svensson, Peter Höglund, Naomi Clyne
Background.: Sarcopenia and poor physical function are common in patients with chronic kidney disease (CKD). Our aim was to investigate the relationships between muscle mass and measured glomerular filtration rate (GFR) and between muscle mass and strength and balance, respectively, in patients with CKD stages 3-5. Methods.: This is a baseline data analysis of a randomized controlled clinical trial. A total of 148 adult patients with an estimated GFR <30 mL/min/1...
March 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28338837/associations-of-leukocyte-telomere-length-with-aerobic-and-muscular-fitness-in-young-adults
#3
Dylan M Williams, Jessica L Buxton, Marko T Kantomaa, Tuija H Tammelin, Alexandra I F Blakemore, Marjo-Riitta Järvelin
Decline in both telomere length and physical fitness over the life course may contribute to increased risk of several chronic diseases. The relationship between telomere length and aerobic and muscular fitness is not well characterized. We examined whether there are cross-sectional associations of mean relative leukocyte telomere length (LTL) with objective measures of aerobic fitness, muscle strength, and muscle endurance, using data on 31-year-old participants of the Northern Finland Birth Cohort 1966 (n = 4,952-5,205, varying by exposure-outcome analysis)...
March 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28338400/systematic-unintended-drifts-in-the-cyclic-force-produced-with-the-fingertips
#4
Satyajit Ambike, Daniela Mattos, Vladimir M Zatsiorsky, Mark Latash
Cyclic isometric finger-force patterns established using visual feedback show systematic drifts when the feedback is removed. Force changes at multiple time scales and opposite directions have been reported. For further characterization of these drifts, healthy subjects produced isometric, cyclic finger force with and without visual feedback at various initial amplitudes and frequencies. We hypothesized that on feedback removal, the amplitude will be attracted towards a preferred value that is frequency dependent...
March 24, 2017: Motor Control
https://www.readbyqxmd.com/read/28338369/dha-rich-fish-oil-increases-the-omega-3-index-and-lowers-the-oxygen-cost-of-physiologically-stressful-cycling-in-trained-individuals
#5
Lachlan Hingley, Michael J Macartney, Marc A Brown, Peter L McLennan, Gregory E Peoples
Dietary fish oil, providing docosahexaenoic acid (DHA) modulates oxygen consumption and fatigue in animal models. However, in humans predominately supplemented with high eicosapentaenoic acid (EPA), there is no evidence of endurance performance enhancement. Therefore, this study examined if DHA-rich fish oil could improve repeated bouts of physiologically stressful cycling and a subsequent time trial in a state of fatigue. Twenty-six trained males took part in a double-blind study and were supplemented with either 2x1g/day soy oil (Control) or DHA-rich tuna fish oil (Nu-Mega) (FO) (560mg DHA / 140mg eicosapentaenoic acid (EPA)) for eight weeks...
March 24, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28337597/the-functional-role-of-post-movement-beta-oscillations-in-motor-termination
#6
Elizabeth Heinrichs-Graham, Max J Kurz, James E Gehringer, Tony W Wilson
Shortly after movement termination, there is a strong increase or resynchronization of the beta rhythm (15-30 Hz) across the sensorimotor network of humans, known as the post-movement beta rebound (PMBR). This response has been associated with active inhibition of the motor network following the completion of a movement, sensory afferentation of the sensorimotor cortices, and other functions. However, studies that have directly probed the role of the PMBR in movement execution have reported mixed results, possibly due to differences in the amount of total motor output and/or movement complexity...
March 24, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28337027/obesity-induced-decreases-in-muscle-performance-are-not-reversed-by-weight-loss
#7
F Seebacher, J Tallis, K McShea, R S James
BACKGROUND/OBJECTIVES: Obesity can affect muscle phenotypes, and may thereby constrain movement and energy expenditure. Weight loss is a common and intuitive intervention for obesity, but it is not known whether the effects of obesity on muscle function are reversible by weight loss. Here we tested whether obesity-induced changes in muscle metabolic and contractile phenotypes are reversible by weight loss. SUBJECTS/METHODS: We used zebrafish (Danio rerio) in a factorial design to compare energy metabolism, locomotor capacity, muscle isometric force and work-loop power output, and myosin heavy chain composition between lean fish, diet-induced obese fish, and fish that were obese and then returned to lean body mass following diet restriction...
March 24, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28335033/lingual-alveolar-contact-pressure-during-speech-in-amyotrophic-lateral-sclerosis-preliminary-findings
#8
Jeff Searl, Stephanie Knollhoff, Richard J Barohn
Purpose: This preliminary study on lingual-alveolar contact pressures (LACP) in people with amyotrophic lateral sclerosis (ALS) had several aims: (a) to evaluate whether the protocol induced fatigue, (b) to compare LACP during speech (LACP-Sp) and during maximum isometric pressing (LACP-Max) in people with ALS (PALS) versus healthy controls, (c) to compare the percentage of LACP-Max utilized during speech (%Max) for PALS versus controls, and (d) to evaluate relationships between LACP-Sp and LACP-Max with word intelligibility...
March 23, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28332714/phosphate-increase-during-fatigue-affects-crossbridge-kinetics-in-intact-mouse-muscle-at-physiological-temperature
#9
M Nocella, G Cecchi, B Colombini
Actomyosin ATP hydrolysis during muscle contraction releases inorganic phosphate, increasing [Pi ] in the myoplasm. Experiments in skinned fibres at low temperature (10-12°C) have shown that [Pi ] increase depresses isometric force and alters the kinetics of actomyosin interaction. However, Pi effects decrease with temperature and this raises the question of Pi role under physiological conditions. The present experiments were made to investigate this point. Intact fibre bundles isolated from the flexor digitorum brevis of C57BL/6 mice were stimulated with a series of tetanic contractions at 1...
March 23, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28332029/brief-submaximal-isometric-exercise-improves-cold-pressor-pain-tolerance
#10
Emily Foxen-Craft, Lynnda M Dahlquist
Exercise-induced hypoalgesia (EIH), or the inhibition of pain following physical exercise, has been demonstrated in adults, but its mechanisms have remained unclear due to variations in methodology. This study aimed to address methodological imitations of past studies and contribute to the literature demonstrating the generalizability of EIH to brief submaximal isometric exercise and cold pressor pain. Young adults (n = 134) completed a baseline cold pressor trial, maximal voluntary contraction (hand grip strength) assessment, 10-min rest, and either a 2-min submaximal isometric handgrip exercise or a sham exercise in which no force was exerted, followed by a cold pressor posttest...
March 22, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28331306/is-cardiac-autonomic-modulation-during-upper-limb-isometric-contraction-and-valsalva-maneuver-impaired-in-copd-patients
#11
Cássia da Luz Goulart, Ramona Cabiddu, Paloma de Borba Schneiders, Elisabete Antunes San Martin, Renata Trimer, Audrey Borghi-Silva, Andréa Lúcia Gonçalves da Silva
PURPOSE: To evaluate the heart rate variability (HRV) indices and heart rate (HR) responses during isometric contraction (IC) and Valsalva maneuver (VM) in COPD patients. METHODS: Twenty-two stable moderate to severe COPD patients were evaluated. R-R intervals were recorded (monitor Polar(®) S810i) during dominant upper limb IC (2 minutes). Stable signals were analyzed by Kubios HRV(®) software. Indices of HRV were computed in the time domain (mean HR; square root of the mean squared differences of successive RR intervals [RMSSD] and HRV triangular index [RR tri index]) and in the frequency domain (high frequency [HF]; low frequency [LF] and LF/HF ratio)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28331221/relationship-between-joint-torque-and-muscle-fascicle-shortening-at-various-joint-angles-and-intensities-in-the-plantar-flexors
#12
Atsuki Fukutani, Jun Misaki, Tadao Isaka
Because it is difficult to measure tendon length changes directly in humans, tendon length changes during dynamic movement have been evaluated indirectly from changes in muscle fascicle length and joint angle. The purpose of this study was to examine the validity of the indirect method. Twitch contractions of the ankle plantar flexors were evoked isometrically in eight subjects. Twitch contractions evoked by singlet, doublet, and triplet stimulations were conducted at dorsiflexion 20° (DF20), plantar flexion 0° (PF0), and plantar flexion 20° (PF20)...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28330923/allometric-growth-in-reef-building-corals
#13
Maria Dornelas, Joshua S Madin, Andrew H Baird, Sean R Connolly
Predicting demographic rates is a critical part of forecasting the future of ecosystems under global change. Here, we test if growth rates can be predicted from morphological traits for a highly diverse group of colonial symbiotic organisms: scleractinian corals. We ask whether growth is isometric or allometric among corals, and whether most variation in coral growth rates occurs at the level of the species or morphological group. We estimate growth as change in planar area for 11 species, across five morphological groups and over 5 years...
March 29, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28330816/the-prospective-evaluation-of-changes-in-fatty-infiltration-and-shoulder-strength-in-nonsurgically-treated-rotator-cuff-tears
#14
Yoshihiro Nakamura, Shin Yokoya, Yohei Harada, Katsunori Shiraishi, Nobuo Adachi, Mitsuo Ochi
BACKGROUND: The purpose of this study was to evaluate the relationship of fatty infiltration in rotator cuff muscles and shoulder strength in rotator cuff tears and these changes during nonsurgical treatment. METHODS: Fifty-three shoulders from 47 patients (mean age: 69.9 years) diagnosed with rotator cuff tears by magnetic resonance imaging (MRI) were treated nonsurgically. The degrees of fatty infiltration in supraspinatus (SSP) and infraspinatus (ISP) muscles were graded by the modified Goutallier classification (grade 0-1, grade 2-3, or grade 4)...
March 19, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28326439/a-distinct-functional-distribution-of-%C3%AE-and-%C3%AE-motoneurons-in-the-rat-trigeminal-motor-nucleus
#15
Yukako Morita-Isogai, Hajime Sato, Mitsuru Saito, Eriko Kuramoto, Dong Xu Yin, Takeshi Kaneko, Takashi Yamashiro, Kenji Takada, Seog Bae Oh, Hiroki Toyoda, Youngnam Kang
Gamma-motoneurons (γMNs) play a crucial role in regulating isometric muscle contraction. The slow jaw-closing during mastication is one of the most functional isometric contractions, which is developed by the rank-order recruitment of alpha-motoneurons (αMNs) in a manner that reflects the size distribution of αMNs. In a mouse spinal motor nucleus, there are two populations of small and large MNs; the former was identified as a population of γMNs based on the positive expression of the transcription factor estrogen-related receptor 3 (Err3) and negative expression of the neuronal DNA-binding protein NeuN, and the latter as that of αMNs based on the opposite pattern of immunoreactivity...
March 22, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28325123/effect-of-stimulation-of-cold-receptors-with-menthol-on-emg-activity-of-quadriceps-muscle-during-low-load-contraction
#16
Tadayuki Tokunaga, Hitoshi Sugawara, Chigaya Tadano, Masuo Muro
PURPOSE: Facilitatory and inhibitory responses of spinal motor neurons are influenced by somatosensory input from the skin. The purpose of this study, employing electromyography, was to examine the neuromuscular changes that occur with menthol applied to the skin over the quadriceps muscle. METHODS: Forty-two healthy volunteers performed isometric knee extensions at 35% maximum voluntary contraction (MVC) in three groups (Adult Placebo, Adult Menthol, Older Adult Menthol)...
March 21, 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/28324992/age-related-neuromuscular-changes-in-semg-of-m-tibialis-anterior-using-higher-order-statistics-gaussianity-linearity-test
#17
Ariba Siddiqi, Sridhar P Arjunan, Dinesh K Kumar
Age-associated changes in the surface electromyogram (sEMG) of Tibialis Anterior (TA) muscle can be attributable to neuromuscular alterations that precede strength loss. We have used our sEMG model of the Tibialis Anterior to interpret the age-related changes and compared with the experimental sEMG. Eighteen young (20-30 years) and 18 older (60-85 years) performed isometric dorsiflexion at 6 different percentage levels of maximum voluntary contractions (MVC), and their sEMG from the TA muscle was recorded. Six different age-related changes in the neuromuscular system were simulated using the sEMG model at the same MVCs as the experiment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324821/muscular-activity-and-torque-of-the-foot-dorsiflexor-muscles-during-decremental-isometric-test-a-cross-sectional-study
#18
Maria Ruiz-Muñoz, Manuel González-Sánchez, Jaime Martín-Martín, Antonio I Cuesta-Vargas
PURPOSE: To analyse the torque variation level that could be explained by the muscle activation (EMG) amplitude of the three major foot dorsiflexor muscles (tibialis anterior (TA), extensor digitorum longus (EDL), extensor hallucis longus (EHL)) during isometric foot dorsiflexion at different intensities. METHODS: In a cross-sectional study, forty-one subjects performed foot dorsiflexion at 100%, 75%, 50% and 25% of maximal voluntary contractions (MVC) with the hip and knee flexed 90° and the ankle in neutral position (90° between leg and foot)...
November 30, 2016: Foot
https://www.readbyqxmd.com/read/28324754/effects-of-sit-to-stand-training-combined-with-transcutaneous-electrical-stimulation-on-spasticity-muscle-strength-and-balance-ability-in-patients-with-stroke-a-randomized-controlled-study
#19
Kyoung-Sim Jung, Tae-Sung In, Hwi-Young Cho
Sit-to-stand is a fundamental movement of human being for performing mobility and independent activity. However, Stroke people symptoms experience difficulty in conducting the sit-to-stand due to paralysis and especially ankle spasticity. Recently, transcutaneouselectrical- stimulation (TENS) is used to reduce pain but also to manage spasticity. The purpose of this study was to determine (1) whether TENS would lead to ankle spasticity reduction and (2) whether sit-to-stand training combined with TENS would improve spasticity, muscle strength and balance ability in stroke patients...
March 10, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28323584/evidence-for-gz-adaptation-observed-with-wearable-biosensors-during-high-performance-jet-flight
#20
G Merrill Rice, Dallas Snider, Jeffrey L Moore, J Timothy Lavan, Rich Folga, Thomas B VanBrunt
INTRODUCTION: Few studies have evaluated physiological responses to high acceleration forces during actual flight and to our knowledge no normative data has been acquired by technologies such as wearable biosensors during high performance jet aircraft operations. METHODS: In-flight physiological data from an FDA cleared portable triaxial accelerometer and bio-sensor were observed from five active duty F-18 pilots of the Naval Flight Demonstration Squadron (Blue Angels)...
December 1, 2016: Aerospace Medicine and Human Performance
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