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https://www.readbyqxmd.com/read/28653780/gait-training-for-chronic-ankle-instability-improves-neuromechanics-during-walking
#1
Mark A Feger, Joseph M Hart, Susan Saliba, Mark F Abel, Jay Hertel
A novel gait-training device has been shown to improve gait patterns while patients with chronic ankle instability (CAI) are using the device and our current objective was to analyze the effect of structured gait training with the device on plantar pressure and surface electromyography (sEMG) following repeated gait training sessions. Sixteen CAI patients participated. Plantar pressure and sEMG were collected simultaneously during walking pre- and post-gait training. Plantar pressure (pressure time integral, peak pressure, time to peak pressure, contact area, contact time and center of pressure trajectory) of the entire foot and 9 specific regions of the foot were recorded concurrently with sEMG root mean square amplitudes from the anterior tibialis, peroneus longus, medial gastrocnemius, and gluteus medius...
June 27, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28635907/-the-problem-of-obstructive-sleep-apnea-syndrome-in-asthmatic-patients
#2
E G Sheludko, D E Naumov, Yu M Perelman, V P Kolosov
Asthma and obstructive sleep apnea syndrome (OSAS) are one of the most common chronic respiratory diseases. These have common risk factors that include obesity, gastroesophageal reflux disease (GERD) and impaired nasal breathing (allergic rhinitis, sinusitis). At the same time, experimental evidence demonstrates common pathophysiological mechanisms of these diseases, such as involvement in the process of the respiratory tract, a systemic inflammatory response, and implementation of neuromechanical reflexes...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28616042/cerebral-mechanism-of-puncturing-at-he-mu-point-combination-for-functional-dyspepsia-study-protocol-for-a-randomized-controlled-parallel-trial
#3
Shuai Yin, Yuan Chen, Du Lei, Rui-Rui Sun, Ting-Ting Ma, Pei-Min Feng, Zhao-Xuan He, Xue-Ling Suo, Pei-Hong Ma, Yu-Zhu Qu, Ke Qiu, Miao-Miao Jing, Qi-Yong Gong, Fan-Rong Liang, Jiao Chen, Fang Zeng
Acupuncture is widely used to treat functional dyspepsia with satisfactory outcomes. Combination of the He and Mu acupoints is commonly used and has a synergistic effect on functional dyspepsia; however, its underlying mechanisms remain unclear. Therefore, a randomized controlled parallel clinical trial is currently underway at Chengdu University of Traditional Chinese Medicine, China. This trial is designed to explore the efficacy of and central responses to the He-Mu point combination in patients with functional dyspepsia using functional magnetic resonance imaging...
May 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28611619/hammering-does-not-fit-fitts-law
#4
Tadej Petrič, Cole S Simpson, Aleš Ude, Auke J Ijspeert
While movement is essential to human wellbeing, we are still unable to reproduce the deftness and robustness of human movement in automatons or completely restore function to individuals with many types of motor impairment. To better understand how the human nervous system plans and controls movements, neuromechanists employ simple tasks such as upper extremity reaches and isometric force tasks. However, these simple tasks rarely consider impacts and may not capture aspects of motor control that arise from real-world complexity...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28599118/sensory-metrics-of-neuromechanical-trust
#5
William Softky, Criscillia Benford
Today digital sources supply a historically unprecedented component of human sensorimotor data, the consumption of which is correlated with poorly understood maladies such as Internet addiction disorder and Internet gaming disorder. Because both natural and digital sensorimotor data share common mathematical descriptions, one can quantify our informational sensorimotor needs using the signal processing metrics of entropy, noise, dimensionality, continuity, latency, and bandwidth. Such metrics describe in neutral terms the informational diet human brains require to self-calibrate, allowing individuals to maintain trusting relationships...
June 9, 2017: Neural Computation
https://www.readbyqxmd.com/read/28598121/-regional-homogeneity-changes-in-patients-with-social-anxiety-disorders-after-cognitive-behavioral-therapy
#6
Min-Lan Yuan, Zheng-Jia Ren, Hong-Ru Zhu, Yan Zhang, Ya-Jing Meng, Wei Zhang
OBJECTIVES: To examine the altered spontaneous brain activity in patients with social anxiety disorders (SAD) before and after cognitive behavior therapy (CBT),and determine the neuromechanism of formation,treatment and recovery of SAD. METHODS: Fifteen SAD patients were treated with an eight-week group CBT.The patients underwent functional magnetic resonance imaging (fMRI) at resting state before and after the treatments.Eighteen healthy controls (HC) were recruited and underwent a baseline fMRI scan...
November 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28541901/changes-of-shoulder-elbow-and-wrist-stiffness-matrix-post-stroke
#7
Li-Qun Zhang, Jongsang Son, Hyung-Soon Park, Sang Hoon Kang, Yunju Lee, Yupeng Ren
Stroke affects multiple joints in the arm with stereotypical patterns of arm deformity involving the shoulder, elbow, wrist and hand and with disrupted coordination of multiple joints in active movements. However, there is a lack of systematic methods to evaluate multi-joints and multi-degree of freedoms (DOF) neuromechanical changes, especially for complex systems with three or more joints/DOFs involved. This study used a novel systematic method to characterize dynamics and control of the shoulder, elbow and wrist of the human arm individually and simultaneously, including the couplings across the multiple joints during controlled movements...
May 23, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28501420/manipulation-of-visual-information-affects-control-strategy-during-a-visuomotor-tracking-task
#8
Paulina J M Bank, Lucas R M Dobbe, Carel G M Meskers, Jurriaan H de Groot, Erwin de Vlugt
Proper understanding of motor control requires insight into the extent and manner in which task performance and control strategy are influenced by various aspects of visual information. We therefore systematically manipulated the visual presentation (i.e., scaling factor and optical flow density) of a visuomotor tracking task without changing the task itself, and investigated the effect on performance, effort, motor control strategy (i.e., anticipatory or corrective steering) and underlying neuromechanical parameters (i...
June 30, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28486092/evaluating-the-ergonomic-benefit-of-a-wrist-brace-on-wrist-posture-muscle-activity-rotational-stiffness-and-peak-shovel-ground-impact-force-during-a-simulated-tree-planting-task
#9
Peter J Sheahan, Joshua G A Cashaback, Steven L Fischer
Background Tree planters are at a high risk for wrist injury due to awkward postures and high wrist loads experienced during each planting cycle, specifically at shovel-ground impact. Wrist joint stiffness provides a measure that integrates postural and loading information. Objective The purpose of this study was to evaluate wrist joint stiffness requirements at the instant of shovel-ground impact during tree planting and determine if a wrist brace could alter muscular contributions to wrist joint stiffness...
May 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28450833/optimal-control-based-stiffness-identification-of-an-ankle-foot-orthosis-using-a-predictive-walking-model
#10
Manish Sreenivasa, Matthew Millard, Martin Felis, Katja Mombaur, Sebastian I Wolf
Predicting the movements, ground reaction forces and neuromuscular activity during gait can be a valuable asset to the clinical rehabilitation community, both to understand pathology, as well as to plan effective intervention. In this work we use an optimal control method to generate predictive simulations of pathological gait in the sagittal plane. We construct a patient-specific model corresponding to a 7-year old child with gait abnormalities and identify the optimal spring characteristics of an ankle-foot orthosis that minimizes muscle effort...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28444866/new-insights-into-neurogenic-cyclic-motor-activity-in-the-isolated-guinea-pig-colon
#11
M Costa, L Wiklendt, L Keightley, S J H Brookes, P G Dinning, N J Spencer
BACKGROUND: The contents of the guinea pig distal colon consist of multiple pellets that move anally in a coordinated manner. This row of pellets results in continued distention of the colon. In this study, we have investigated quantitatively the features of the neurally dependent colonic motor patterns that are evoked by constant distension of the full length of guinea-pig colon. METHODS: Constant distension was applied to the excised guinea-pig by high-resolution manometry catheters or by a series of hooks...
April 26, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28431748/a-benchtop-biorobotic-platform-for-in-vitro-observation-of-muscle-tendon-dynamics-with-parallel-mechanical-assistance-from-an-elastic-exoskeleton
#12
Benjamin D Robertson, Siddarth Vadakkeveedu, Gregory S Sawicki
We present a novel biorobotic framework comprised of a biological muscle-tendon unit (MTU) mechanically coupled to a feedback controlled robotic environment simulation that mimics in vivo inertial/gravitational loading and mechanical assistance from a parallel elastic exoskeleton. Using this system, we applied select combinations of biological muscle activation (modulated with rate-coded direct neural stimulation) and parallel elastic assistance (applied via closed-loop mechanical environment simulation) hypothesized to mimic human behavior based on previously published modeling studies...
March 21, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28427305/neuromechanical-adaptations-during-a-robotic-powered-exoskeleton-assisted-walking-session
#13
Arvind Ramanujam, Christopher M Cirnigliaro, Erica Garbarini, Pierre Asselin, Rakesh Pilkar, Gail F Forrest
OBJECTIVE: To evaluate gait parameters and neuromuscular profiles of exoskeleton-assisted walking under Max Assist condition during a single-session for; (i) able bodied (AB) individuals walking assisted with (EXO) and without (non-EXO) a powered exoskeleton, (ii) non-ambulatory SCI individuals walking assisted with a powered exoskeleton. DESIGN: Single-session. SETTING: Motion analysis laboratory. PARTICIPANTS: Four AB individuals and four individuals with SCI...
April 20, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28396411/mechanosensation-is-evolutionarily-tuned-to-locomotor-mechanics
#14
Brett R Aiello, Mark W Westneat, Melina E Hale
The biomechanics of animal limbs has evolved to meet the functional demands for movement associated with different behaviors and environments. Effective movement relies not only on limb mechanics but also on appropriate mechanosensory feedback. By comparing sensory ability and mechanics within a phylogenetic framework, we show that peripheral mechanosensation has evolved with limb biomechanics, evolutionarily tuning the neuromechanical system to its functional demands. We examined sensory physiology and mechanics of the pectoral fins, forelimb homologs, in the fish family Labridae...
April 25, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28381996/evaluation-of-a-neuromechanical-walking-control-model-using-disturbance-experiments
#15
Seungmoon Song, Hartmut Geyer
Neuromechanical simulations have been used to study the spinal control of human locomotion which involves complex mechanical dynamics. So far, most neuromechanical simulation studies have focused on demonstrating the capability of a proposed control model in generating normal walking. As many of these models with competing control hypotheses can generate human-like normal walking behaviors, a more in-depth evaluation is required. Here, we conduct the more in-depth evaluation on a spinal-reflex-based control model using five representative gait disturbances, ranging from electrical stimulation to mechanical perturbation at individual leg joints and at the whole body...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28351197/the-human-central-pattern-generator-for-locomotion
#16
Karen Minassian, Ursula S Hofstoetter, Florin Dzeladini, Pierre A Guertin, Auke Ijspeert
The ability of dedicated spinal circuits, referred to as central pattern generators (CPGs), to produce the basic rhythm and neural activation patterns underlying locomotion can be demonstrated under specific experimental conditions in reduced animal preparations. The existence of CPGs in humans is a matter of debate. Equally elusive is the contribution of CPGs to normal bipedal locomotion. To address these points, we focus on human studies that utilized spinal cord stimulation or pharmacological neuromodulation to generate rhythmic activity in individuals with spinal cord injury, and on neuromechanical modeling of human locomotion...
March 1, 2017: Neuroscientist: a Review Journal Bringing Neurobiology, Neurology and Psychiatry
https://www.readbyqxmd.com/read/28282755/the-acute-effects-of-an-intense-stretch-shortening-cycle-fatigue-protocol-on-the-neuromechanical-parameters-of-lower-limbs-in-men-and-prepubescent-boys
#17
Savvas Lazaridis, Dimitrios A Patikas, Eleni Bassa, Themistoklis Tsatalas, Konstantinos Hatzikotoulas, Christos Ftikas, Christos Kotzamanidis
The study examined the differences between boys and adults after an intense stretch-shortening cycle fatigue protocol on neuromechanical parameters of the lower limb. Thirteen boys (9-11 years old) and 13 adult men (22-28 years old) were tested for maximal isometric voluntary knee extension torque and drop jump (DJ) performance from 30 cm before and immediately after a fatigue protocol, consisted of 10 × 10 maximum effort vertical jumps. Three-dimensional kinematics, kinetics and electromyographic (EMG) parameters of the lower extremities muscles were recorded during DJs before and after the fatigue test...
February 8, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28280881/tryptophan-depletion-affects-compulsive-behaviour-in-rats-strain-dependent-effects-and-associated-neuromechanisms
#18
A Merchán, S V Navarro, A B Klein, S Aznar, L Campa, C Suñol, M Moreno, P Flores
RATIONALE: Compulsive behaviour, present in different psychiatric disorders, such as obsessive-compulsive disorder, schizophrenia and drug abuse, is associated with altered levels of monoamines, particularly serotonin (5-hydroxytryptamine) and its receptor system. OBJECTIVES: The present study investigated whether 5-HT manipulation, through a tryptophan (TRP) depletion by diet in Wistar and Lister Hooded rats, modulates compulsive drinking in schedule-induced polydipsia (SIP) and locomotor activity in the open-field test...
April 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28279574/activity-patterns-of-extrinsic-finger-flexors-and-extensors-during-movements-of-instructed-and-non-instructed-fingers
#19
Nathalie van Beek, Dick F Stegeman, Josien C van den Noort, DirkJan H E J Veeger, Huub Maas
The fingers of the human hand cannot be controlled fully independently. This phenomenon may have a neurological as well as a mechanical basis. Despite previous studies, the neuromechanics of finger movements are not fully understood. The aims of this study were (1) to assess the activation and coactivation patterns of finger specific flexor and extensor muscle regions during instructed single finger flexion and (2) to determine the relationship between enslaved finger movements and respective finger muscle activation...
February 21, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28269975/effects-of-detraining-on-neuromuscular-performance-in-a-selected-group-of-elite-women-pole-vaulters-a-case-study
#20
Irineu Loturco, Lucas A Pereira, Ronaldo Kobal, Henrique C Martins, Katia Kitamura, Cesar C Abad, Fabio Y Nakamura
The aim of this paper was to determine the effects of 28 days of inactivity on neuromuscular performance of elite women pole-vaulters. Four athletes undertook measurements of rate of force development (RFD), unloaded and loaded vertical jump tests, drop jumps and a 45 m sprint test before and after a transition period of planned inactivity. The RFD, the ability to accelerate over very short distances (5 m) and sprinting capacity improved after training cessation. Acceleration over longer distances (5-45 m) was impaired, while unloaded and loaded vertical jump tests suffered trivial to small changes...
April 2017: Journal of Sports Medicine and Physical Fitness
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