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https://www.readbyqxmd.com/read/28651422/-meta-analysis-on-the-diagnostic-value-of-laser-doppler-imaging-for-burn-depth
#1
Y Huang, L Qiu, A L Mei, J X Li
Objective: To evaluate the value of laser Doppler imaging (LDI) in diagnosing deep or superficial partial-thickness burn wound with meta-analysis. Methods: Databases including PubMed, Cochrane Library were searched using key words " burn, burns, burn depth, laser Doppler imaging, laser Doppler perfusion imaging, LDI, LDPI" , and Chinese Journals Full-text Database, Wanfang Database, VIP Database were searched using Chinese key words ",,,," to obtain the published trials of LDI in diagnosing deep or superficial partial-thickness burn wound from the establishment of each database to October 2015...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651128/local-up-regulation-of-interferon-%C3%AE-ifn-%C3%AE-following-disc-herniation-is-involved-in-the-inflammatory-response-underlying-acute-lumbar-radicular-pain
#2
Gunn-Helen Moen, Aurora Moen, Elina I Schistad, Johannes Gjerstad
Lumbar radicular pain after disc herniation may be associated with release of pro-inflammatory cytokines from nucleus pulposus (NP) tissue. In the present study we examined the role of interferon-γ (IFN-γ) and cluster of differentiation 68 (CD68) in the acute phase of this process. First, in an animal model mimicking the clinical situation after disc herniation, the role of IFN-γ close to the dorsal nerve roots was studied. Next, in patients with lumbar radicular pain due to disc herniation, we examined how two single nucleotide polymorphisms (SNPs; rs2069705 and rs2069718) are important for the IFN-γ expression influenced the pain behavior...
June 23, 2017: Cytokine
https://www.readbyqxmd.com/read/28650791/deproteinizing-agents-as-an-effective-enamel-bond-enhancer-an-in-vitro-study
#3
Pallavi Hasija, Vinod Sachdev, Shivani Mathur, Rishi Rath
OBJECTIVE: The aim of this study was to compare the effect of different deproteinizing agents on shear bond strength of composite to primary teeth enamel. STUDY DESIGN: Forty sound primary molars divided in 4 groups of 10 teeth each. In control group 1, enamel was etched for 60 seconds with 37% phosphoric acid and rinsed with water. Group 2: after acid etching deproteinizing agent 5 % sodium hypochlorite was applied for 60 seconds and rinsed. Group 3: after acid etching deproteinizing agent papain gel was applied for 60 seconds and rinsed...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28650706/commentary-on-comparison-of-adjacent-segment-degeneration-after-nonrigid-fixation-system-and-posterior-lumbar-inter-body-fusion-for-single-level-lumbar-disc-herniation-a-new-method-of-mri-analysis-of-lumbar-nucleuspulposus-volumen
#4
Máximo-Alberto Díez-Ulloa
No abstract text is available yet for this article.
June 26, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28650688/multidrug-resistant-enterobacteriaceae-in-lebanese-hospital-wastewater-implication-in-the-one-health-concept
#5
Ziad Daoud, Jina Farah, Elie S Salem, Khalil El Kfoury, Elias Dahdouh, Khalil Masri, Claude Afif, Roula M Abdel-Massih, Ghassan M Matar
Extended-spectrum beta-lactamases (ESBL) and carbapenemase-producing organisms pose severe problems for hospitalized patients. In the absence of efficient sanitation and sewage disposal, the risks for transmission of hospital organisms into the community are high. Our objectives were to study the occurrence and mechanisms of resistance of multidrug-resistant gram-negative bacilli in two Lebanese hospital sewage treatment plants. Wastewater samples were collected, filtered, and cultivated on MacConckey+cefotaxime agars...
June 26, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28648143/polymorphism-rs547984-on-human-chromosome-1q43-is-not-associated-with-primary-open-angle-glaucoma-in-a-saudi-cohort
#6
Taif A Azad, Nikhil B Edward, Altaf A Kondkar, Hatem Kalantan, Saleh Altuwaijri, Tahira Sultan, Faisal A Al-Mobarak, Saleh A Al-Obeidan, Khaled K Abu-Amero
BACKGROUND: To investigate the association between polymorphism rs547984, located in close proximity to the Zona Pellucida Glycoprotein 4 (ZP4) gene on human chromosome 1q43 and primary open angle glaucoma (POAG). METHOD: Polymorphism rs547984 was genotyped using Taq-Man® assay in 185 subjects comprising of 90 unrelated POAG cases and 95 controls of Saudi origin. RESULTS: Association analysis between cases and controls revealed no significant genotype distribution under additive (p = 0...
June 26, 2017: Journal of Negative Results in Biomedicine
https://www.readbyqxmd.com/read/28647468/influence-of-rabbit-notochordal-cells-on-symptomatic-intervertebral-disc-degeneration-anti-angiogenic-capacity-on-human-endothelial-cell-proliferation-under-hypoxia
#7
Woo-Keun Kwon, Hong Joo Moon, Taek-Hyun Kwon, Youn-Kwan Park, Joo Han Kim
OBJECTIVES: Symptomatic degenerative disc disease (DDD) is associated with neovascularization and nerve ingrowth into intervertebral discs (IVDs). Notochordal cells (NCs) are key cells that may lead to regeneration of IVDs. However, their activities under conditions of hypoxia, the real environment of IVD, are not well known. We hypothesized that NCs may inhibit neovascularization by interacting with endothelial cells (ECs) under hypoxia. DESIGN: Human IVDs were isolated and cultured to produce nucleus pulposus (NP) cell conditioned medium (NPCM)...
June 21, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28646704/location-and-characterization-of-lignin-in-tracheid-cell-walls-of-radiata-pine-pinus-radiata-d-don-compression-woods
#8
Miao Zhang, Catherine Lapierre, Noor Liyana Nouxman, Michel K Nieuwoudt, Bronwen G Smith, Ramesh R Chavan, Brian H McArdle, Philip J Harris
Tilted stems of softwoods form compression wood (CW) and opposite wood (OW) on their lower and upper sides, respectively. More is known about the most severe form of CW, severe CW (SCW), but mild CWs (MCWs) also occur widely. Two grades of MCWs, MCW1 and MCW2, as well as SCW and OW were identified in the stems of radiata pine (Pinus radiata) that had been slightly tilted. The four wood types were identified by the distribution of lignin in the tracheid walls determined by fluorescence microscopy. A solution of the fluorescent dye acridine orange (AO) (0...
June 15, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28646455/human-nucleus-pulposus-intervertebral-disc-cells-becoming-senescent-using-different-treatments-exhibit-a-similar-transcriptional-profile-of-catabolic-and-inflammatory-genes
#9
Sotiris-Spyros Vamvakas, Eleni Mavrogonatou, Dimitris Kletsas
PURPOSE: Chronic low back pain has been associated with intervertebral disc (IVD) degeneration, which is characterized by the accumulation of extracellular matrix (ECM)-degrading proteases and inflammatory molecules in the degenerate tissue. IVD degeneration could be the outcome of natural organismal ageing and/or of the exposure of the disc to cumulative stressful environmental stimuli and is accompanied by an increased population of senescent cells in the tissue. On the other hand, senescent cells are known to secrete proteolytic enzymes and inflammatory molecules, which can contribute to ECM catabolism...
June 23, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28646343/clinical-outcome-following-anterior-cervical-discectomy-and-fusion-with-and-without-anterior-cervical-plating-for-the-treatment-of-cervical-disc-herniation-a-25-year-follow-up-study
#10
Benedikt W Burkhardt, Moritz Brielmaier, Karsten Schwerdtfeger, Joachim M Oertel
Extreme long-term clinical outcome studies following anterior cervical discectomy and fusion (ACDF) with an autologous iliac crest with and without Caspar plating (ACDF + CP) for the treatment of radiculopathy caused by cervical disc herniation (CDH) are extremely rare. Hospital records of patients who underwent ACDF or ACDF + CP for the treatment of CDH at least 17 years ago were reviewed. Information about diagnosis, surgery, pre- and postoperative clinical process, and repeated procedure was analyzed...
June 23, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28646230/il-1%C3%AE-increases-asporin-expression-via-the-nf-%C3%AE%C2%BAb-p65-pathway-in-nucleus-pulposus-cells-during-intervertebral-disc-degeneration
#11
Shengjie Wang, Chao Liu, Zhongyi Sun, Peng Yan, He Liang, Kai Huang, Changwei Li, Jiwei Tian
Disc degeneration (DD) is a multifaceted chronic process that alters the structure and function of intervertebral discs. The pathophysiology of degeneration is not completely understood, but the consensus is that changes in genes encoding extracellular matrix (ECM) proteins in the disc are the leading factors contributing to DD. Asporin is an ECM protein that has been shown to be increased in degenerated intervertebral discs, but little is known about how asporin is regulated during DD. In exploring the intricate mechanism, we confirmed that asporin was abundantly increased in patients' degenerated nucleus pulposus...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28645675/anatomical-considerations-of-the-iliac-crest-on-percutaneous-endoscopic-discectomy-using-a-transforaminal-approach
#12
Fumitake Tezuka, Toshinori Sakai, Mitsunobu Abe, Kazuta Yamashita, Yoichiro Takata, Kosaku Higashino, Akihiro Nagamachi, Takashi Chikawa, Koichi Sairyo
BACKGROUND CONTEXT: Percutaneous endoscopic discectomy (PED) is a minimally invasive procedure for the surgical treatment of lumbar disc herniation (LDH). It can be performed under local anesthesia and requires a skin incision of only 8 mm, with minimal disruption of the spinal structures including ligaments and muscles. However, performing PED with a transforaminal approach (TF-PED) for the lower lumbar spine is associated with some anatomical problems such as interference from the iliac crest...
June 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28645515/adaptations-in-rod-outer-segment-disc-membranes-in-response-to-environmental-lighting-conditions
#13
Tatini Rakshit, Subhadip Senapati, Vipul M Parmar, Bhubanananda Sahu, Akiko Maeda, Paul S H Park
The light-sensing rod photoreceptor cell exhibits several adaptations in response to the lighting environment. While adaptations to short-term changes in lighting conditions have been examined in depth, adaptations to long-term changes in lighting conditions are less understood. Atomic force microscopy was used to characterize the structure of rod outer segment disc membranes, the site of photon absorption by the pigment rhodopsin, to better understand how photoreceptor cells respond to long-term lighting changes...
June 20, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28645289/degenerative-changes-of-the-canine-cervical-spine-after-discectomy-procedures-an-in-vivo-study
#14
Peter Grunert, Yu Moriguchi, Brian P Grossbard, Rodolfo J Ricart Arbona, Lawrence J Bonassar, Roger Härtl
BACKGROUND: Discectomies are a common surgical treatment for disc herniations in the canine spine. However, the effect of these procedures on intervertebral disc tissue is not fully understood. The objective of this study was to assess degenerative changes of cervical spinal segments undergoing discectomy procedures, in vivo. RESULTS: Discectomies led to a 60% drop in disc height and 24% drop in foraminal height. Segments did not fuse but showed osteophyte formation as well as endplate sclerosis...
June 23, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28645219/pullulan-microbeads-si-hpmc-hydrogel-injectable-system-for-the-sustained-delivery-of-gdf-5-and-tgf-%C3%AE-1-new-insight-into-intervertebral-disc-regenerative-medicine
#15
Nina Henry, Johann Clouet, Audrey Fragale, Louise Griveau, Claire Chédeville, Joëlle Véziers, Pierre Weiss, Jean Le Bideau, Jérôme Guicheux, Catherine Le Visage
Discogenic low back pain is considered a major health concern and no etiological treatments are today available to tackle this disease. To clinically address this issue at early stages, there is a rising interest in the stimulation of local cells by in situ injection of growth factors targeting intervertebral disc (IVD) degenerative process. Despite encouraging safety and tolerability results in clinic, growth factors efficacy may be further improved. To this end, the use of a delivery system allowing a sustained release, while protecting growth factors from degradation appears of particular interest...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28644852/comparisons-of-retinal-vessel-diameter-and-glaucomatous-parameters-between-both-eyes-of-subjects-with-clinically-unilateral-pseudoexfoliation-syndrome
#16
Yasuyuki Takai, Masaki Tanito, Tetsuro Omura, Ryo Kawasaki, Yumiko Kawasaki, Akihiro Ohira
PURPOSE: Pseudoexfoliation syndrome (PEX), the most common identifiable cause of open-angle glaucoma, might affect the retinal hemodynamics. To test this, we compared retinal vessel diameter and glaucoma-related parameters between eyes with pseudoexfoliation material (PE+) and fellow unaffected (PE-) eyes of patients with clinically unilateral PEX. METHODS: The medical records of 30 consecutive Japanese subjects were reviewed retrospectively. The retinal vessel diameters were measured and expressed as the central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) using standardized software...
2017: PloS One
https://www.readbyqxmd.com/read/28644561/the-redox-sensitive-module-of-cyclophilin-20-3-2-cysteine-peroxiredoxin-and-cysteine-synthase-integrates-sulfur-metabolism-and-oxylipin-signaling-in-the-high-light-acclimation-response
#17
Sara M Müller, Shanshan Wang, Wilena Telman, Michael Liebthal, Helena Schnitzer, Andrea Viehhauser, Carsten Sticht, Carolina Delatorre, Markus Wirtz, Rüdiger Hell, Karl-Josef Dietz
The integration of redox- and reactive oxygen species-dependent signaling and metabolic activities are fundamental to plant acclimation to biotic and abiotic stresses. Previous data suggest the existence of a dynamically interacting module in the chloroplast stroma consisting of cyclophilin 20-3 (Cyp20-3), O-acetylserine(thiol)lyase B (OASTL-B), 2-cysteine peroxiredoxins A/B (2-CysPrx) and serine acetyltransferase 2;1 (SERAT2;1). The functionality of this COPS module is influenced by redox stimuli and oxophytodienoic acid (OPDA) which is the precursor for jasmonic acid...
June 23, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28644413/clonal-diversity-of-esbl-producing-escherichia-coli-isolated-from-environmental-human-and-food-samples
#18
Elena Ojer-Usoz, David González, Ana Isabel Vitas
This study presents a comprehensive approach of a clonal diversity analysis of 448 Extended-spectrum β-lactamase (ESBL)-producing E. coli isolated from environmental, human and food samples in Spain. The phenotypic confirmation of ESBL production was performed by disc diffusion and microdilution methods, while Polymerase Chain Reaction (PCR) and sequencing were used for the molecular characterization of β-lactamase genes (blaCTX-M, blaSHV, blaTEM, blaOXA). Clonal relationship of isolates was determined by multi-locus sequence typing (MLST)...
June 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28643966/-what-is-the-role-of-surgery-in-low-back-pain-associated-with-modic-changes
#19
Pietro Aniello Laudato, Viktor Bartanusz
Benign low back pain is frequent in the lucratively active population. Degenerative changes are considered the most frequent causes. The identification of pain generators remain challenging. Bone marrow lesions, Modic changes, are frequently associated with benign low back pain, mostly type 1. The etiology of Modic changes is unknown, both infectious and autoimmune mechanisms have been suggested. Despite the strong association of Modic changes with low back pain it is not clear whether lumbar surgery (lumbar fusion, total disc replacement) has any role in the management of these patients...
June 21, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28643926/fluid-pressurization-and-tractional-forces-during-tmj-disc-loading-a-biphasic-finite-element-analysis
#20
Y Wu, S E Cisewski, F Wei, X She, T S Gonzales, L R Iwasaki, J C Nickel, H Yao
OBJECTIVES: To investigate the ploughing mechanism associated with tractional force formation on the temporomandibular joint (TMJ) disc surface. SETTING AND SAMPLE POPULATION: Ten left TMJ discs were harvested from 6- to 8-month-old male Yorkshire pigs. MATERIALS AND METHODS: Confined compression tests characterized mechanical TMJ disc properties, which were incorporated into a biphasic finite element model (FEM). The FEM was established to investigate load carriage within the extracellular matrix (ECM) and the ploughing mechanism during tractional force formation by simulating previous in vitro plough experiments...
June 2017: Orthodontics & Craniofacial Research
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