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Dementia care

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https://www.readbyqxmd.com/read/28323838/bupropion-for-the-treatment-of-apathy-in-huntington-s-disease-a-multicenter-randomised-double-blind-placebo-controlled-prospective-crossover-trial
#1
Harald Gelderblom, Torsten Wüstenberg, Tim McLean, Lisanne Mütze, Wilhelm Fischer, Carsten Saft, Rainer Hoffmann, Sigurd Süssmuth, Peter Schlattmann, Erik van Duijn, Bernhard Landwehrmeyer, Josef Priller
OBJECTIVE: To evaluate the efficacy and safety of bupropion in the treatment of apathy in Huntington's disease (HD). METHODS: In this phase 2b multicentre, double-blind, placebo-controlled crossover trial, individuals with HD and clinical signs of apathy according to the Structured Clinical Interview for Apathy-Dementia (SCIA-D), but not depression (n = 40) were randomized to receive either bupropion 150/300mg or placebo daily for 10 weeks. The primary outcome parameter was a significant change of the Apathy Evaluation Scale (AES) score after ten weeks of treatment as judged by an informant (AES-I) living in close proximity with the study participant...
2017: PloS One
https://www.readbyqxmd.com/read/28323819/development-of-an-adaptive-personalized-and-scalable-dementia-care-program-early-findings-from-the-care-ecosystem
#2
Katherine L Possin, Jennifer Merrilees, Stephen J Bonasera, Alissa Bernstein, Winston Chiong, Kirby Lee, Leslie Wilson, Sarah M Hooper, Sarah Dulaney, Tamara Braley, Sutep Laohavanich, Julie E Feuer, Amy M Clark, Michael W Schaffer, A Katrin Schenk, Julia Heunis, Paulina Ong, Kristen M Cook, Angela D Bowhay, Rosalie Gearhart, Anna Chodos, Georges Naasan, Andrew B Bindman, Daniel Dohan, Christine Ritchie, Bruce L Miller
Katherine Possin and colleagues report on the implementation, development, and early findings of the Care Ecosystem, an adaptive, personalized, and scalable dementia care program.
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28319312/exploratory-study-of-australian-aged-care-staff-knowledge-and-attitudes-of-later-life-sexuality
#3
Yung-Hui Chen, Cindy Jones, Debora Osborne
OBJECTIVE: To explore aged care staff knowledge and attitudes towards later life sexuality and attitudes about intimacy in people with dementia. METHODS: Fifty-two care staff working in two aged care facilities with secure dementia care units were recruited. Knowledge and attitudes on later life sexuality and attitudes towards later life sexuality in people with dementia were surveyed using the Aging Sexual Knowledge and Attitudes Scale and the selected eight items of the Staff Attitudes about Intimacy and Dementia, respectively...
March 20, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28317166/the-relationship-of-specific-items-on-the-neuropsychiatric-inventory-to-caregiver-burden-in-dementia-a-systematic-review
#4
REVIEW
Toril Marie Terum, John Roger Andersen, Arvid Rongve, Dag Aarsland, Ellen J Svendsboe, Ingelin Testad
OBJECTIVE: Neuropsychiatric symptoms (NPSs) are common in dementia, and they have been identified as important care-recipient variables in terms of their impact on caregiver burden. The aim of this review was to describe how individual NPSs in dementia, assessed using the Neuropsychiatric Inventory, are associated with caregiver burden. METHODS: We performed a systematic review of English language, peer-reviewed articles retrieved from MEDLINE, PSYCINFO, and EMBASE...
March 20, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28317009/development-of-an-instrument-to-assess-social-functioning-in-dementia-the-social-functioning-in-dementia-scale-sf-dem
#5
Andrew Sommerlad, David Singleton, Rebecca Jones, Sube Banerjee, Gill Livingston
INTRODUCTION: Social functioning is a core domain in the life of people with dementia, but there is no accepted instrument to measure it. We aimed to develop the Social Functioning in Dementia (SF-DEM) scale and test its psychometric properties for assessing social function in people with dementia. METHODS: We interviewed people with mild dementia and family caregivers to develop patient and caregiver-rated SF-DEM versions and refined them through interviews with health care professionals...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28315156/-evaluation-by-case-managers-dementia-an-explorative-practice-based-study-on-types-and-content
#6
Nicole A B M Ketelaar, Jan S Jukema, Marlies van Bemmel, Marian J M Adriaansen, Carolien H M Smits
BACKGROUND: This practice based explorative study aims to provide insight into the ways in which case managers shape and fill up the evaluation phase of their support of the informal care network of persons with dementia. METHOD: A combination of quantitative and qualitative research methods were used. A group of 57 case managers of persons with dementia in three different organisational networks took part in this study. RESULTS: Results from the quantitative and qualitative data are organized into four themes: (1) attitude towards evaluation, (2) forms of evaluation, (3) implementation of evaluation and (4) content of evaluation...
March 17, 2017: Tijdschrift Voor Gerontologie en Geriatrie
https://www.readbyqxmd.com/read/28315047/putting-dementia-awareness-into-general-practice-the-cadif-approach
#7
Michael Pentzek, Horst Christian Vollmar, Stefan Wilm, Verena Leve
BACKGROUND: International studies show that dementia is often recognized at later stages in general practice. Pure knowledge-sharing interventions could not change this in a sustainable manner. Concepts for changing attitudes of general practitioners (GPs) are required. OBJECTIVES: What barriers affect GPs' recognition of and diagnostic approach to dementia? What recommendations for a GP-specific diagnostic procedure can be derived from this? METHODS: Metasynthesis of qualitative studies with GPs on barriers to dementia recognition, explication of the "frailty" concept and the diagnostic approach described therein and the development of an approach in cases of suspected cognitive decline in a multiprofessional team...
March 17, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28306661/referring-patients-to-hospice-or-palliative-care
#8
Kathleen Broglio, Anne Walsh
NPs care for patients with chronic diseases such as heart failure, chronic obstructive pulmonary disease, cancer, and dementia. As the disease progresses or patients age, disease-related symptoms may become increasingly burdensome, and these patients may benefit from hospice or palliative care. NPs can guide individuals in this process to optimize care and support at the end of life.
April 16, 2017: Nurse Practitioner
https://www.readbyqxmd.com/read/28304297/information-and-communication-technologies-for-the-activities-of-daily-living-in-older-patients-with-dementia-a-systematic-review
#9
Grazia D'Onofrio, Daniele Sancarlo, Francesco Ricciardi, Francesco Panza, Davide Seripa, Filippo Cavallo, Francesco Giuliani, Antonio Greco
BACKGROUND: Significant innovations have been introduced in recent years in the application of information and communication technologies (ICTs) to support healthcare for patients with dementia. OBJECTIVE: In the present systematic review, our goal is to keep track of ICT concepts and approaches to support the range of activities of daily living for people with dementia and to provide a snapshot of the effect that technology is having on patients' self-reliance...
March 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28304285/what-drives-country-differences-in-cost-of-alzheimer-s-disease-an-explanation-from-resource-use-in-the-geras-study
#10
Catherine Reed, Michael Happich, Josep Maria Argimon, Josep Maria Haro, Anders Wimo, Giuseppe Bruno, Richard Dodel, Roy W Jones, Bruno Vellas, Mark Belger
BACKGROUND: Country differences in resource use and costs of Alzheimer's disease (AD) may be driven by differences in health care systems and resource availability. OBJECTIVE: To compare country resource utilization drivers of societal costs for AD dementia over 18 months. METHODS: GERAS is an observational study in France (n = 419), Germany (n = 550), and the UK (n = 526). Resource use of AD patients and caregivers contributing to >1% of total societal costs (year 2010) was assessed for country differences, adjusting for participant characteristics...
March 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28302633/systematic-review-of-systematic-reviews-of-non-pharmacological-interventions-to-treat-behavioural-disturbances-in-older-patients-with-dementia-the-senator-ontop-series
#11
Iosief Abraha, Joseph M Rimland, Fabiana Mirella Trotta, Giuseppina Dell'Aquila, Alfonso Cruz-Jentoft, Mirko Petrovic, Adalsteinn Gudmundsson, Roy Soiza, Denis O'Mahony, Antonio Guaita, Antonio Cherubini
OBJECTIVE: To provide an overview of non-pharmacological interventions for behavioural and psychological symptoms in dementia (BPSD). DESIGN: Systematic overview of reviews. DATA SOURCES: PubMed, EMBASE, Cochrane Database of Systematic Reviews, CINAHL and PsycINFO (2009-March 2015). ELIGIBILITY CRITERIA: Systematic reviews (SRs) that included at least one comparative study evaluating any non-pharmacological intervention, to treat BPSD...
March 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28298891/white-matter-deterioration-may-foreshadow-impairment-of-emotional-valence-determination-in-early-stage-dementia-of-the-alzheimer-type
#12
Ravi Rajmohan, Ronald C Anderson, Dan Fang, Austin G Meyer, Pavis Laengvejkal, Parunyou Julayanont, Greg Hannabas, Kitten Linton, John Culberson, Hafiz M R Khan, John De Toledo, P Hemachandra Reddy, Michael O'Boyle
In Alzheimer Disease (AD), non-verbal skills often remain intact for far longer than verbally mediated processes. Four (1 female, 3 males) participants with early-stage Clinically Diagnosed Dementia of the Alzheimer Type (CDDAT) and eight neurotypicals (NTs; 4 females, 4 males) completed the emotional valence determination test (EVDT) while undergoing BOLD functional magnetic resonance imaging (fMRI). We expected CDDAT participants to perform just as well as NTs on the EVDT, and to display increased activity within the bilateral amygdala and right anterior cingulate cortex (r-ACC)...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28296910/examining-the-construct-and-known-group-validity-of-a-composite-endpoint-for-the-older-persons-and-informal-caregivers-survey-minimum-data-set-topics-mds-a-large-scale-data-sharing-initiative
#13
Cynthia S Hofman, Jennifer E Lutomski, Han Boter, Bianca M Buurman, Anton J M de Craen, Rogier Donders, Marcel G M Olde Rikkert, Peter Makai, René J F Melis
BACKGROUND: Preference-weighted multi-faceted endpoints have the potential to facilitate comparative effectiveness research that incorporates patient preferences. The Older Persons and Informal Caregivers Survey-Composite endpoint (TOPICS-CEP) is potentially a valuable outcome measure for evaluating interventions in geriatric care as it combines multiple outcomes relevant to older persons in a single metric. The objective of this study was to validate TOPICS-CEP across different study settings (general population, primary care and hospital)...
2017: PloS One
https://www.readbyqxmd.com/read/28296176/mini-mental-state-examination-score-trajectories-and-incident-disabling-dementia-among-community-dwelling-older-japanese-adults
#14
Yu Taniguchi, Akihiko Kitamura, Hiroshi Murayama, Hidenori Amano, Tomohiro Shinozaki, Isao Yokota, Satoshi Seino, Yu Nofuji, Mariko Nishi, Yuri Yokoyama, Yutaka Matsuyama, Yoshinori Fujiwara, Shoji Shinkai
AIM: The present prospective study used repeated measures analysis to identify potential Mini-Mental State Examination (MMSE) score trajectories and determine whether MMSE trajectory was associated with incident disabling dementia among community-dwelling older Japanese adults. METHODS: A total of 1724 non-demented adults (mean age 71.4 years [SD 5.7]; 56.7% women) aged 65-90 years participated in annual geriatric health assessments during the period from June 2002 through July 2014...
March 14, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28295142/creation-of-an-interprofessional-teledementia-clinic-for-rural-veterans-preliminary-data
#15
Becky B Powers, Marcia C Homer, Natalia Morone, Natali Edmonds, Michelle I Rossi
The teledementia clinic is a new model of care that expands the reach of specialized geriatric and dementia care using clinical video telehealth (CVT) to rural veterans, who frequently lack access to specialty care. The clinic is a Veterans Affairs (VA) Geriatric Research, Education, and Clinical Center clinical demonstration project. It is located in the Pittsburgh VA Healthcare System tertiary referral hospital and serves veterans in affiliated rural community-based outpatient clinics (CBOCs). Rural CBOC primary care providers refer clinic patients, or referral is according to previous cognitive impairment diagnosis in a VAPHS geriatric clinic...
March 10, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28295138/frequency-and-risk-factors-for-live-discharge-from-hospice
#16
David Russell, Eli L Diamond, Bonnie Lauder, Ritchell R Dignam, Dawn W Dowding, Timothy R Peng, Holly G Prigerson, Kathryn H Bowles
OBJECTIVES: To report frequencies and associated risk factors for 4 distinct causes of live discharge from hospice. DESIGN: Retrospective cohort study using electronic medical records of hospice patients who received care from a large urban not-for-profit hospice agency in New York City during a 3-year period between 2013 and 2015 (n = 9,190). RESULTS: Roughly one in five hospice patients were discharged alive (21%; n = 1911). Acute hospitalization was the most frequent reason for live discharge (42% of all live discharges; n = 802)...
March 13, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28295134/impact-of-the-reach-ii-and-reach-va-dementia-caregiver-interventions-on-healthcare-costs
#17
Linda O Nichols, Jennifer Martindale-Adams, Carolyn W Zhu, Erin K Kaplan, Jeffrey K Zuber, Teresa M Waters
OBJECTIVE: Examine caregiver and care recipient healthcare costs associated with caregivers' participation in Resources for Enhancing Alzheimer's Caregivers Health (REACH II or REACH VA) behavioral interventions to improve coping skills and care recipient management. DESIGN: RCT (REACH II); propensity-score matched, retrospective cohort study (REACH VA). SETTING: Five community sites (REACH II); 24 VA facilities (REACH VA). PARTICIPANTS: Care recipients with Alzheimer's disease and related dementias (ADRD) and their caregivers who participated in REACH II study (analysis sample of 110 caregivers and 197 care recipients); care recipients whose caregivers participated in REACH VA and a propensity matched control group (analysis sample of 491)...
March 13, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28294929/-written-advance-euthanasia-directives-in-mentally-incompetent-patients-with-dementia-a-systematic-review-of-the-literature
#18
K de Nooijer, V E van de Wetering, E C T Geijteman, L Postma, J A C Rietjens, A van der Heide
OBJECTIVE: To present the knowledge, experiences and attitudes of the general population, patients, relatives and health care professionals concerning written advance euthanasia directives in patients who have become mentally incompetent. DESIGN: Systematic review of the literature. METHOD: We systematically searched Medline, Cochrane Library and Embase for articles published in the period 2002-2016. RESULTS: The search yielded 775 articles, of which 11 met the inclusion criteria...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28294010/no-place-for-ageism-in-health-care
#19
Nina Mitchell
Ageism was not something I thought about during my training, but I became aware of it on a clinical placement working with older people, some of whom had dementia.
March 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28293113/prevalence-of-dementia-in-egypt-a-systematic-review
#20
REVIEW
Mohamed H Elshahidi, Muhammad A Elhadidi, Ahmed A Sharaqi, Ahmed Mostafa, Mohamed A Elzhery
BACKGROUND: With the growing prevalence of dementia worldwide, two-third of the people with dementia are projected to be from the developing countries by 2050. AIM: This study reviews the literature regarding dementia prevalence in Egypt. METHODS: Six databases were systematically searched from their dates of inception till July 2016. Studies published in English and reporting dementia prevalence among nonhospitalized individuals after clinical examinations were considered eligible...
2017: Neuropsychiatric Disease and Treatment
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