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Biomechanic

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https://www.readbyqxmd.com/read/28345593/microstructural-tissue-engineering-in-the-rachis-and-barbs-of-bird-feathers
#1
Theagarten Lingham-Soliar
Feathers do not have to be especially strong but they do need to be stiff and at the same time resilient and to have a high work of fracture. Syncitial barbule fibres are the highest size-class of continuous filaments in the cortex of the rachis of the feather. However, the rachis can be treated as a generalized cone of rapidly diminishing volume. This means that hundreds of syncitial barbule fibres of the rachis may have to be terminated before reaching the tip - creating potentially thousands of inherently fatal crack-like defects...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28345410/transplantation-of-chemically-processed-decellularized-meniscal-allografts
#2
Kolja Gelse, Ludwig Körber, Martin Schöne, Kay Raum, Peter Koch, Milena Pachowsky, Götz Welsch, Roman Breiter
Objective The aim of this study was to evaluate the chondroprotective effect of chemically decellularized meniscal allografts transplanted into the knee joints of adult merino sheep. Methods Lateral sheep meniscal allografts were chemically processed by a multistep method to yield acellular, sterile grafts. The grafts were transplanted into the knee joints of sheep that were treated by lateral meniscectomy. Joints treated by meniscectomy only and untreated joints served as controls. The joints were analyzed morphologically 6 and 26 weeks after surgery by the macroscopical and histological OARSI (Osteoarthritis Research Society International) score...
April 2017: Cartilage
https://www.readbyqxmd.com/read/28344561/fetal-growth-restriction-induces-heterogeneous-effects-on-vascular-biomechanical-and-functional-properties-in-guinea-pigs-cavia-porcellus
#3
Daniel Cañas, Emilio A Herrera, Claudio García-Herrera, Diego Celentano, Bernardo J Krause
Aim: Fetal growth restriction (FGR) is associated with a variety of cardiometabolic diseases in adulthood which could involve remodeling processes of the vascular walls that could start in the fetal period. However, there is no consensus whether this remodeling affects in a similar way the whole vascular system. We aimed to determine the effects of FGR on the vasoactive and biomechanical properties of umbilical and systemic vessels in fetal guinea pigs. Methods: FGR was induced by implanting ameroid occluders at mid-gestation in uterine arteries of pregnant guinea pigs, whilst the control group was exposed to simulated surgery...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28344464/the-biomechanics-of-standing-start-and-initial-acceleration-reliability-of-the-key-determining-kinematics
#4
Regan J Standing, Peter S Maulder
The reliability of the key determining kinematic variables associated with short sprint performance provide insight into how and why movement may vary between individual trials. Currently, literature surrounding these determinants is scarce when investigating the first three strides of a sprint. The purpose of this study was to investigate the reliability of sprint acceleration and the key kinematic determinants involved during the first three steps of the movement. The aim was to use a practical method of kinematic analysis to help explain why changes may occur in sprint performance via the use of correlative statistics and to provide reference values for intervention research to make conclusions about their change scores...
March 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28344451/retrospective-injury-epidemiology-and-risk-factors-for-injury-in-crossfit
#5
Alicia M Montalvo, Hilary Shaefer, Belinda Rodriguez, Tan Li, Katrina Epnere, Gregory D Myer
The objective of the study is to examine injury epidemiology and risk factors for injury in CrossFit athletes. A survey was administered to athletes at four owner-operated facilities in South Florida. Respondents reported number, location of injury, and training exposure from the preceding six months and answered questions regarding potential risk factors for injury. Fifty out of 191 athletes sustained 62 injuries during CrossFit participation in the preceding six months. The most frequently injured locations were the shoulder, knee, and lower back...
March 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28343925/influence-of-alveolar-bone-loss-and-cement-layer-thickness-on-the-biomechanical-behavior-of-endodontically-treated-maxillary-incisors-a-3-dimensional-finite-element-analysis
#6
Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Rodrigo Othávio de Assunção E Souza, Alexandre Luiz Souto Borges
INTRODUCTION: In order to understand the mechanical behavior of a weakened incisor, this study aimed to evaluate the stress distribution caused by different alveolar bone heights and cement layer thickness. METHODS: A finite element analysis was conducted for this investigation. An intact maxillary central incisor was initially modeled, and the bone of the models was modified in order to simulate 4 levels of bone height: BL0 (no bone loss), BL1 (1/3 bone loss), BL2 (1/2 bone loss), and BL3 (2/3 bone loss)...
March 23, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28343746/preliminary-development-of-an-advanced-modular-pressure-relief-cushion-testing-and-user-evaluation
#7
Tyler Freeto, Steven J Mitchell, Kath M Bogie
STUDY AIM: Effective pressure relief cushions are identified as a core assistive technology need by the World Health Organization Global Cooperation on Assistive Technology. High quality affordable wheelchair cushions could provide effective pressure relief for many individuals with limited access to advanced assistive technology. MATERIALS: Value driven engineering (VdE) principles were employed to develop a prototype modular cushion. Low cost dynamically responsive gel balls were arranged in a close packed array and seated in bilayer foam for containment and support...
March 20, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28342099/optimized-decellularization-protocol-including-%C3%AE-gal-epitope-reduction-for-fabrication-of-an-acellular-porcine-annulus-fibrosus-scaffold
#8
Lien-Chen Wu, Yi-Jie Kuo, Fu-Wen Sun, Chia-Hsien Chen, Chang-Jung Chiang, Pei-Wei Weng, Yang-Hwei Tsuang, Yi-You Huang
Recent advances in tissue engineering have led to potential new strategies, especially decellularization protocols from natural tissues, for the repair, replacement, and regeneration of intervertebral discs. This study aimed to validate our previously reported method for the decellularization of annulus fibrosus (AF) tissue and to quantify potentially antigenic α-Gal epitopes in the decellularized tissue. Porcine AF tissue was decellularized using different freeze-thaw temperatures, chemical detergents, and incubation times in order to determine the optimal method for cell removal...
March 24, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28341969/computed-tomographic-analysis-of-the-internal-structure-of-the-metacarpals-and-its-implications-for-hand-use-pathology-and-surgical-intervention
#9
Alison L Wong, Clifton G Meals, Christopher B Ruff
The variation of bone structure and biomechanics between the metacarpals is not well characterized. It was hypothesized that their structure would reflect their common patterns of use (i.e., patterns of hand grip), specifically that trabecular bone density would be greater on the volar aspect of all metacarpal bases, that this would be most pronounced in the thumb, and that the thumb diaphysis would have the greatest bending strength. Cross-sections at basal and mid-diaphyseal locations of 50 metacarpals from 10 human hands were obtained by peripheral quantitative computed tomography...
March 24, 2017: Anatomical Science International
https://www.readbyqxmd.com/read/28341831/the-relationship-between-retinal-nerve-fibre-layer-thickness-profiles-and-corvisst-tonometry-measured-biomechanical-properties-in-young-healthy-subjects
#10
Masato Matsuura, Hiroshi Murata, Shunsuke Nakakura, Yoshitaka Nakao, Takehiro Yamashita, Kazunori Hirasawa, Yuri Fujino, Yoshiaki Kiuchi, Ryo Asaoka
We previously reported that a shallow circumpapillary retinal nerve fiber layer (cpRNFL) peak angle as measured by optical coherence tomography (OCT) suggests the temporal retina is stretched around the optic disc from the papillo-macular bundle (Yamashita T et al. Investigative Ophthalmol Vis Sci 2013). The purpose of the current study was to investigate the relationship between CorvisST tonometry (CST) corneal measurements, axial length (AL) and the change in OCT-measured cpRNFL peak angle, in young healthy subjects...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28341826/poly-ethylmethacrylate-co-diethylaminoethyl-acrylate-coating-improves-endothelial-re-population-bio-mechanical-and-anti-thrombogenic-properties-of-decellularized-carotid-arteries-for-blood-vessel-replacement
#11
Elena López-Ruiz, Seshasailam Venkateswaran, Macarena Perán, Gema Jiménez, Salvatore Pernagallo, Juan J Díaz-Mochón, Olga Tura-Ceide, Francisco Arrebola, Juan Melchor, Juan Soto, Guillermo Rus, Pedro J Real, María Diaz-Ricart, Antonio Conde-González, Mark Bradley, Juan A Marchal
Decellularized vascular scaffolds are promising materials for vessel replacements. However, despite the natural origin of decellularized vessels, issues such as biomechanical incompatibility, immunogenicity risks and the hazards of thrombus formation, still need to be addressed. In this study, we coated decellularized vessels obtained from porcine carotid arteries with poly (ethylmethacrylate-co-diethylaminoethylacrylate) (8g7) with the purpose of improving endothelial coverage and minimizing platelet attachment while enhancing the mechanical properties of the decellularized vascular scaffolds...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28340656/advances-in-technology-for-functional-rhinoplasty-the-next-frontier
#12
REVIEW
Sachin S Pawar, Guilherme J M Garcia, John S Rhee
Advances in computer modeling and simulation technologies have the potential to provide facial plastic surgeons with information and tools that can aid in patient-specific surgical planning for rhinoplasty. Finite element modeling and computational fluid dynamics are modeling technologies that have been applied to the nose to study structural biomechanics and nasal airflow. Combining these technologies with patient-specific imaging data and symptom measures has the potential to alter the future landscape of nasal surgery...
May 2017: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/28343260/urethral-lumen-occlusion-by-artificial-sphincteric-devices-a-computational-biomechanics-approach
#13
Arturo Nicola Natali, Emanuele Luigi Carniel, Chiara Giulia Fontanella, Silvia Todros, Giulia Maria De Benedictis, Maria Angela Cerruto, Walter Artibani
The action induced by artificial sphincteric devices to provide urinary continence is related to the problem of evaluating the interaction between the occlusive cuff and the urethral duct. The intensity and distribution of the force induced within the region of application determine a different occlusion process and potential degradation of the urethral tissue, mostly at the borders of the cuff. This problem is generally considered in the light of clinical and surgical operational experience, while a valid cooperation is established with biomechanical competences by means of experimental and numerical investigation...
March 25, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28343086/modeling-the-influence-of-acute-changes-in-bladder-elasticity-on-pressure-and-wall-tension-during-filling
#14
Firdaweke G Habteyes, S Omid Komari, Anna S Nagle, Adam P Klausner, Rebecca L Heise, Paul H Ratz, John E Speich
Tension-sensitive nerves in the bladder wall are responsible for providing bladder sensation. Bladder wall tension, and therefore nerve output, is a function of bladder pressure, volume, geometry and material properties. The elastic modulus of the bladder is acutely adjustable, and this material property is responsible for adjustable preload tension exhibited in human and rabbit detrusor muscle strips and dynamic elasticity revealed during comparative-fill urodynamics in humans. A finite deformation model of the bladder was previously used to predict filling pressure and wall tension using uniaxial tension test data and the results showed that wall tension can increase significantly during filling with relatively little pressure change...
February 20, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28343085/guava-fruit-extract-and-its-triterpene-constituents-have-osteoanabolic-effect-stimulation-of-osteoblast-differentiation-by-activation-of-mitochondrial-respiration-via-the-wnt-%C3%AE-catenin-signaling
#15
Konica Porwal, Subhashis Pal, Kapil Dev, Shyamsundar Pal China, Yogesh Kumar, Chandan Singh, Tarun Barbhuyan, Neeraj Sinha, Sabyasachi Sanyal, Arun Kumar Trivedi, Rakesh Maurya, Naibedya Chattopadhyay
The aim of this study was to evaluate the skeletal effect of guava triterpene-enriched extract (GE) in rats and identify osteogenic compounds thereof, and determine their modes of action. In growing female rats, GE at 250 mg/kg dose increased parameters of peak bone mass including femur length, bone mineral density (BMD) and biomechanical strength, suggesting that GE promoted modeling-directed bone growth. GE also stimulated bone regeneration at the site of bone injury. In adult osteopenic rats (osteopenia induced by ovariectomy, OVX) GE completely restored the lost bones at both axial and appendicular sites, suggesting a strong osteoanabolic effect...
March 8, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28343047/the-odyssey-of-sagittal-pelvic-morphology-during-human-evolution-a-perspective-on-different-hominoidae
#16
Tom P C Schlösser, Michiel M A Janssen, Tom Hogervorst, Tomaž Vrtovec, John de Vos, F Cumhur Öner, René M Castelein
The importance of sagittal spino-pelvic alignment for posture and upright human spinal biomechanics, and its role in the etio-pathogenesis of different spinal pathologies is well recognized. In human evolution, morphological changes of the pelvis are believed to be a crucial step forward towards pertinent bipedalism. By comparison of sagittal pelvic morphology within the superfamily of Hominoidea, we have the perspective that in the course of human evolution, development of a lordosis between the ischium and ilium, and the consequent increase in pelvic incidence allowed for ambulation in a fully upright position while maintaining the lever arm of the ischial musculature...
March 22, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28342975/biomechanical-testing-of-a-peek-based-dynamic-instrumentation-device-in-a-lumbar-spine-model
#17
Christian Herren, Agnes Beckmann, Sabine Meyer, Miguel Pishnamaz, Marion Mundt, Rolf Sobottke, Andreas Prescher, Marcus Stoffel, Bernd Markert, Philipp Kobbe, Hans-Christoph Pape, Peer Eysel, Jan Siewe
BACKGROUND: The purpose of this study was to investigate the range-of-motion after posterior polyetheretherketone-based rod stabilisation combined with a dynamic silicone hinge in order to compare it with titanium rigid stabilisation. METHODS: Five human cadaveric lumbar spines with four vertebra each (L2 to L5) were tested in a temperature adjustable spine-testing set-up in four trials: (1) native measurement; (2) kinematics after rigid monosegmental titanium rod instrumentation with anterior intervertebral bracing of the segment L4/5; (3) kinematics after hybrid posterior polyetheretherketone rod instrumentation combined with a silicone hinge within the adjacent level (L3/4) and (4) kinematics after additional decompression with laminectomy of L4 and bilateral resection of the inferior articular processes (L3)...
March 18, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28342586/biomechanical-analysis-of-the-fixation-systems-for-anterior-column-and-posterior-hemi-transverse-acetabular-fractures
#18
Jianyin Lei, Pengfei Dong, Zhiqiang Li, Feng Zhu, Zhihua Wang, Xianhua Cai
OBJECTIVE: The aim of this study was to evaluate the biomechanical properties of common fixation systems for complex acetabular fractures. METHODS: A finite element (FE) pelvic model with anterior column and posterior hemi-transverse acetabular fractures was created. Three common fixation systems were used to fix the posterior wall acetabular fractures: 1. Anterior column plate combined with posterior column screws (group I), 2. Anterior column plate combined with quadrilateral area screws (group II) and 3...
March 22, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28342508/gender-smoking-body-size-and-aneurysm-geometry-influence-the-biomechanical-rupture-risk-of-abdominal-aortic-aneurysms-as-estimated-by-finite-element-analysis
#19
Moritz Lindquist Liljeqvist, Rebecka Hultgren, Antti Siika, T Christian Gasser, Joy Roy
OBJECTIVE: Finite element analysis (FEA) has been suggested to be superior to maximal diameter measurements in predicting rupture of abdominal aortic aneurysms (AAAs). Our objective was to investigate to what extent previously described rupture risk factors were associated with FEA-estimated rupture risk. METHODS: One hundred forty-six patients with an asymptomatic AAA of a 40- to 60-mm diameter were retrospectively identified and consecutively included. The patients' computed tomography angiograms were analyzed by FEA without (neutral) and with (specific) input of patient-specific mean arterial pressure (MAP), gender, family history, and age...
April 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28340249/orthodontic-strain-affects-the-hippo-pathway-effector-yap-concomitant-with-proliferation-in-human-periodontal-ligament-fibroblasts
#20
Diana Huelter-Hassler, Pascal Tomakidi, Thorsten Steinberg, Britta A Jung
Objectives: During orthodontic tooth movement (OTM), human periodontal ligament fibroblasts (hPDLFs) sense, and respond to mechanical forces. Since the molecular constituents involved in these processes are not fully elucidated, the objective of the present study was to identify further key molecules of the cellular strain response. Materials and Methods: Primary hPDLFs were strained with a static equiaxial strain of 2.5 per cent for 15 minutes, 1 hour, 6 hours, and 24 hours...
March 17, 2017: European Journal of Orthodontics
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