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Biomechanic

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https://www.readbyqxmd.com/read/28538668/biomechanical-modeling-of-pterygium-radiation-surgery-a-retrospective-case-study
#1
Bojan Pajic, Daniel M Aebersold, Andreas Eggspuehler, Frederik R Theler, Harald P Studer
Pterygium is a vascularized, invasive transformation on the anterior corneal surface that can be treated by Strontium-/Yttrium90 beta irradiation. Finite element modeling was used to analyze the biomechanical effects governing the treatment, and to help understand clinically observed changes in corneal astigmatism. Results suggested that irradiation-induced pulling forces on the anterior corneal surface can cause astigmatism, as well as central corneal flattening. Finite element modeling of corneal biomechanics closely predicted the postoperative corneal surface (astigmatism error -0...
May 24, 2017: Sensors
https://www.readbyqxmd.com/read/28538320/the-effects-of-a-heel-wedge-on-hip-pelvis-and-trunk-biomechanics-during-squatting-in-resistance-trained-individuals
#2
Jesse M Charlton, Connor A Hammond, Christopher K Cochrane, Gillian L Hatfield, Michael A Hunt
Charlton, JM, Hammond, CA, Cochrane, CK, Hatfield, GL, and Hunt, MA. The effects of a heel wedge on hip, pelvis, and trunk biomechanics during squatting in resistance trained individuals. J Strength Cond Res 31(6): 1678-1687, 2017-Barbell back squats are a popular exercise for developing lower extremity strength and power. However, this exercise has potential injury risks, particularly to the lumbar spine, pelvis, and hip joint. Previous literature suggests heel wedges as a means of favorably adjusting trunk and pelvis kinematics with the intention of reducing such injury risks...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28538143/openrbc-a-fast-simulator-of-red-blood-cells-at%C3%A2-protein-resolution
#3
Yu-Hang Tang, Lu Lu, He Li, Constantinos Evangelinos, Leopold Grinberg, Vipin Sachdeva, George Em Karniadakis
We present OpenRBC, a coarse-grained molecular dynamics code, which is capable of performing an unprecedented in silico experiment-simulating an entire mammal red blood cell lipid bilayer and cytoskeleton as modeled by multiple millions of mesoscopic particles-using a single shared memory commodity workstation. To achieve this, we invented an adaptive spatial-searching algorithm to accelerate the computation of short-range pairwise interactions in an extremely sparse three-dimensional space. The algorithm is based on a Voronoi partitioning of the point cloud of coarse-grained particles, and is continuously updated over the course of the simulation...
May 23, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28535435/multi-segmental-thoracic-spine-kinematics-measured-dynamically-in-the-young-and-elderly-during-flexion
#4
Dominika Ignasiak, Andrea Rüeger, Stephen J Ferguson
In contrast to the cervical and lumbar region, the normal kinematics of the thoracic spine have not been thoroughly investigated. The aim of this study was to characterize normal multi-segmental continuous motion of the whole thoracolumbar spine, during a flexion maneuver, in young and elderly subjects. Forty-two healthy volunteers were analyzed: 21 young (age=27.00±3.96) and 21 elderly (age=70.1±3.85). Spinal motion was recorded with a motion-capture system and analyzed using a 3rd order polynomial function to approximate spinal curvature throughout the motion sequence...
May 20, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28535384/invertebrate-biomechanics
#5
S N Patek, A P Summers
Invertebrate biomechanics focuses on mechanical analyses of non-vertebrate animals, which at root is no different in aim and technique from vertebrate biomechanics, or for that matter the biomechanics of plants and fungi. But invertebrates are special - they are fabulously diverse in form, habitat, and ecology and manage this without the use of hard, internal skeletons. They are also numerous and, in many cases, tractable in an experimental and field setting. In this Primer, we will probe three axes of invertebrate diversity: worms (Phylum Annelida), spiders (Class Arachnida) and insects (Class Insecta); three habitats: subterranean, terrestrial and airborne; and three integrations with other fields: ecology, engineering and evolution...
May 22, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28535145/substrate-curvature-regulates-cell-migration
#6
Xiuxiu He, Yi Jiang
Cell migration is essential in many aspects of biology. Many basic migration processes, including adhesion, membrane protrusion and tension, cytoskeletal polymerization, and contraction, have to act in concert to regulate cell migration. At the same time, substrate topography modulates these processes. In this work, we study how substrate curvature at micrometer scale regulates cell motility. We have developed a 3D mechanical model of single cell migration and simulated migration on curved substrates with different curvatures...
May 23, 2017: Physical Biology
https://www.readbyqxmd.com/read/28534698/effect-of-parathyroid-hormone-on-healing-in-osteoporotic-fractures-via-a-phospholipase-c-independent-pathway
#7
Wei-Long Li, Xiao Yu, Zhi-Ping Huang, Qing-Jiang Pang
Objective This study was performed to investigate the effect of parathyroid hormone (PTH) on healing in osteoporotic fractures via a phospholipase C (PLC)-independent pathway and explore the mechanism of PTH-mediated bone formation. Methods Ninety-six 12-week-old C57BL/6J female mice underwent bilateral ovariectomy. One month later, the lower third of the femur was fractured and the mice were treated using saline, PTH(1-28), PTH(1-34), zoledronic acid (ZA), PTH(1-28)+ZA, and PTH(1-34)+ZA. The mice were killed at weeks 2 and 4 in each group...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28534073/surgical-treatment-of-intraforaminal-extraforaminal-lumbar-disc-herniations-many-approaches-for-few-surgical-routes
#8
REVIEW
Giorgio Lofrese, Lorenzo Mongardi, Francesco Cultrera, Giorgio Trapella, Pasquale De Bonis
BACKGROUND: Several disc disease nomenclatures and approaches for LDH exist. The traditional midline bone-destructive procedures together with approaches requiring extreme muscular retraction are being replaced by muscle sparing, targeted, stability-preserving surgical routes. The increasing speculation on LDHs and the innovative corridors described to treat them have lead to an extensive production of papers frequently treating the same topic but adopting different terminologies and reporting contradictory results...
May 22, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28533965/reappraisal-of-the-extinct-seal-phoca-vitulinoides-from-the-neogene-of-the-north-sea-basin-with-bearing-on-its-geological-age-phylogenetic-affinities-and-locomotion
#9
Leonard Dewaele, Eli Amson, Olivier Lambert, Stephen Louwye
BACKGROUND: Discovered on the southern margin of the North Sea Basin, "Phoca" vitulinoides represents one of the best-known extinct species of Phocidae. However, little attention has been given to the species ever since its original 19th century description. Newly discovered material, including the most complete specimen of fossil Phocidae from the North Sea Basin, prompted the redescription of the species. Also, the type material of "Phoca" vitulinoides is lost. METHODS: "Phoca" vitulinoides is redescribed...
2017: PeerJ
https://www.readbyqxmd.com/read/28533626/nonhealing-progressive-stress-fractures-of-the-foot-in-a-13-year-old-basketball-player-is-vitamin-k-deficiency-a-risk-factor
#10
Meral Bayramoğlu, Nuray Ünlütürk
[Purpose] To report an adolescent male basketball player with nonhealing stress fractures of the foot and discuss the probable factors. [Subject and Methods] A 13-year-old basketball player presented with right foot pain. He had been playing basketball for three years and practicing 5 days/week. He denied any increase in daily training intensity. Magnetic resonance imaging confirmed stress fractures of the cuboid and cuneiform, with mild edema of the soft tissues between the tarsal bones and tenosynovitis of the flexor hallucis and flexor digitorum longi...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28533609/gait-abnormalities-in-patients-with-chronic-ankle-instability-can-improve-following-a-non-invasive-biomechanical-therapy-a-retrospective-analysis
#11
Shay Tenenbaum, Ofir Chechik, Jason Bariteau, Nathan Bruck, Yiftah Beer, Mazen Falah, Ganit Segal, Amit Mor, Avi Elbaz
[Purpose] The purpose of this study was to evaluate the changes in gait patterns and clinical outcomes of patients with chronic ankle instability (CAI) following treatment with a home-based non-invasive biomechanical device. [Subjects and Methods] Thirty-three patients with CAI were compared with 43 healthy controls. Patients underwent a spatiotemporal gait assessment before and three months following treatment. Clinical evaluation was recorded with SF-36 Health Survey and the Foot and Ankle Outcome Score (FAOS)...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28533398/correction-for-pivkin-et-al-biomechanics-of-red-blood-cells-in-human-spleen-and-consequences-for-physiology-and-disease
#12
(no author information available yet)
No abstract text is available yet for this article.
May 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28532919/image-guided-lateral-mass-osteotomy-for-en-bloc-resection-of-cervical-ewing-s-sarcoma-a-technical-note
#13
Julian Li, Kevin Phan, Tommy Manh Tran, Ralph Mobbs, Ralph Stanford
BACKGROUND: En bloc resection of Ewing's sarcoma according to Enneking's principles is technically challenging in the cervical spine due to the proximity of important neurovascular structures, complex local anatomy and biomechanical instability of radical resection. The rarity of Ewing's sarcoma and variability of presentation justifies ongoing compilation of the surgical nuances and subtleties of en bloc resection in the cervical spine. CASE DESCRIPTION: We present a 34-year-old male with Ewing's sarcoma of the neck who underwent successful en bloc resection using a novel technique of splitting the laminae and osteomising the lateral masses using image guidance...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28532897/mast-cells-improve-functional-recovery-of-transected-peripheral-nerve-a-novel-preliminary-study
#14
Behrooz Ilkhanizadeh, Leila Zarei, Negin Farhad, Mehran Bahrami-Bukani, Rahim Mohammadi
BACKGROUND: Employment of regenerative properties of cells at the service of nerve repair has been initiated during recent decades. Effects of local transplantation of bone marrow-derived mast cells on peripheral nerve regeneration were studied using a rat sciatic nerve transection model. MATERIALS AND METHODS: A 10-mm sciatic nerve defect was bridged using a conduit chitosan-based hybrid conduit filled with BMMCs in BMMC group. In positive control group (Pos), the conduit was filled with phosphate-buffered saline alone...
May 11, 2017: Injury
https://www.readbyqxmd.com/read/28532164/statistical-factorial-analysis-approach-for-parameter-calibration-on-material-nonlinearity-of-intervertebral-disc-finite-element-model
#15
Masni-Azian, Masao Tanaka
In the biomechanics field, material parameters calibration is significant for finite element (FE) model to ensure a legit estimation of biomechanical response. Determining an appropriate combination of calibration factors is challenging as each constitutive component responds differently. This study proposes a statistical factorial analysis approach using L16(4(5)) orthogonal array to evaluate material nonlinearity and applicable calibration factor of the intervertebral disc FE model in pure moment. The calibrated model exhibits improved agreement to the experimental findings for all directions...
May 22, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28530471/structure-function-relationships-of-temporomandibular-retrodiscal-tissue
#16
M C Coombs, J M Petersen, G J Wright, S H Lu, B J Damon, H Yao
It is estimated that 2% to 4% of the US population will seek treatment for temporomandibular joint (TMJ) symptoms, typically occurring with anterior disc displacement. The temporomandibular retrodiscal tissue (RDT) has been postulated to restrict pathologic disc displacement. To elucidate RDT function, understanding regional RDT biomechanics and ultrastructure is required. No prior biomechanical analysis has determined regional variations in RDT properties or associated biomechanical outcomes with regional variations in collagen and elastin organization...
June 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28530449/a-new-elastic-slot-system-and-v-wire-mechanics
#17
Andrea Wichelhaus
OBJECTIVE: To biomechanically test a new elastic slot system and V-wire mechanics. MATERIALS AND METHODS: Conventional twin and self-ligating brackets and the new elastodynamic bracket were biomechanically tested. The conventional brackets had a rectangular 0.022'' slot and the new elastodynamic bracket had a V-slot, a new slot geometry. Torque measurements were performed with 0.018'' × 0.025'' and 0.019'' × 0.025'' stainless steel (ss) archwires. A nickel-titanium V wire was used for the biomechanical measurements on the elastodynamic bracket...
May 22, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28530131/a-novel-combination-of-a-polycaprolactone-fumarate-pclf-scaffold-with-polyethylene-terephthalate-pet-sutures-for-intra-articular-ligament-regeneration
#18
Joshua Parry, Eric R Wagner, Peter Kok, Mahrokh Dadsetan, Michael J Yaszemski, Andre J van Wijnen, Sanjeev Kakar
Intra-articular ligamentous injuries are typically unrepairable and have limited outcomes after graft reconstruction. A combination of porous polycaprolactone fumarate (PCLF) scaffolds with polyethylene terephthalate (PET) sutures was developed with the goal of regenerating intra-articular ligaments. Scaffolds were fabricated by injecting PCLF over 3D-printed molds containing two strands of PET suture down its central pore followed by crosslinking. Scaffolds were seeded with human mesenchymal stem cells (MSCs) from adipose tissue...
May 20, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28530074/-patellofemoral-instability-anatomy-clinical-evaluation-imaging-and-treatment
#19
REVIEW
Noam Shohat, Dror Lindner, Iftach Beer, Gabriel Agar
Patellofemoral instability is a complex anatomical phenomena that requires deep understanding. The cause for instability could be a result of an anatomical defect or a soft tissue pathology. A thorough patient history, physical examination and imaging are paramount for a correct diagnosis and for deciding on the correct treatment. The proper treatment is often debatable. Conservative treatment is suitable for acute dislocation but has a high failure rate in chronic instability, which usually necessitates surgical treatment...
November 2016: Harefuah
https://www.readbyqxmd.com/read/28530017/mechanical-stress-by-spasticity-accelerates-fracture-healing-after-spinal-cord-injury
#20
Naoyoshi Sakitani, Hiroyuki Iwasawa, Masato Nomura, Yasushi Miura, Hiroshi Kuroki, Junya Ozawa, Hideki Moriyama
Accelerated fracture healing in patients with spinal cord injuries (SCI) is often encountered in clinical practice. However, there is no distinct evidence in the accelerated fracture healing, and the mechanisms of accelerated fracture healing in SCI are poorly understood. We aimed to determine whether SCI accelerated fracture healing in morphology and strength, to characterize the healing process with SCI, and to clarify the factors responsible for accelerated fracture healing. In total, 39 male Wistar rats were randomly divided into healthy control without intervention, SCI only, fracture with SCI, botulinum toxin (BTX) A-treated fracture with SCI, and propranolol-treated fracture with SCI groups...
May 22, 2017: Calcified Tissue International
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