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Red yeast rice

Stephanie Maxine Ross
No abstract text is available yet for this article.
January 2017: Holistic Nursing Practice
Mariangela Rondanelli, Attilio Giacosa, Paolo Morazzoni, Davide Guido, Mario Grassi, Gabriella Morandi, Chiara Bologna, Antonella Riva, Pietro Allegrini, Simone Perna
Background. High HDL-cholesterol (HDL-C) values are negatively correlated with cardiovascular diseases. This review analyses the effect of the supplementation with various Mediterranean diet products (artichoke, bergamot, and olive oil) and Asian diet products (red yeast rice) on the HDL-C value in dyslipidemic subjects. Methods. A systematic review has been done involving all the English written studies published from the 1st of January 1958 to the 31st of March 2016. Results. The results of this systematic review indicate that the dietary supplementation with red yeast rice, bergamot, artichoke, and virgin olive oil has promising effects on the increase of HDL-C serum levels...
2016: BioMed Research International
Tina Heinz, Jan Philipp Schuchardt, Katharina Möller, Peyman Hadji, Andreas Hahn
Hypercholesterolemia and elevated homocysteine concentrations are associated with cardiovascular risk. Previous studies have demonstrated a cholesterol-lowering effect of red yeast rice (RYR) supplements which contained 5 to 10 mg of monacolin K. We hypothesized that the intake of a low monacolin K dose may likewise reduce low-density lipoprotein-cholesterol (LDL-C) and other plasma lipids. In secondary analyses, we tested the homocysteine lowering effect of folic acid, which was also included in the study preparation...
October 2016: Nutrition Research
Yogen Patel, Alex B Behar, Chirag D Shah, Ravi E Kasi
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Sangkyu Park, Min Ji Choi, Jong Yeol Lee, Jae Kwang Kim, Sun-Hwa Ha, Sun-Hyung Lim
Anthocyanins and proanthocyanidins, the major flavonoids in black and red rice grains, respectively, are mainly derived from 3',4'-dihydroxylated leucocyanidin. 3'-Hydroxylation of flavonoids in rice is catalyzed by flavonoid 3'-hydroxylase (F3'H: EC We isolated cDNA clones of the two rice F3'H genes (CYP75B3 and CYP75B4) from Korean varieties of white, black, and red rice. Sequence analysis revealed allelic variants of each gene containing one or two amino acid substitutions. Heterologous expression in yeast demonstrated that CYP75B3 preferred kaempferol to other substrates, and had a low preference for dihydrokaempferol...
2016: International Journal of Molecular Sciences
A F G Cicero, M Morbini, M Rosticci, S D'addato, E Grandi, C Borghi
OBJECTIVE: Red yeast rice is a well-known lipid-lowering nutraceutical. The aim of this double-blind, randomized, placebo-controlled, clinical trial was to investigate if the known benefits on lipid pattern of a 6-month treatment with 10 mg monacolins could be also associated to changes in endothelial function and arterial stiffness. DESIGN AND METHOD: This double blind, placebo-controlled, randomized clinical trial was carried out on 40 moderately hypercholesterolemic subjects, non smokers, pharmacologically untreated, in primary prevention for cardiovascular diseases (Clinicaltrial...
September 2016: Journal of Hypertension
L Z Wang, M L Zhou, J W Wang, D Wu, T Yan
Twenty castrated Boer crossbred goats were used in the present study with two treatments to examine the effect of dietary replacement of ordinary rice with red yeast rice on nutrient utilization, enteric methane emission and ruminal archaea structure and composition. Two treatment diets contained (DM basis) 70.0% of forage, 21.8% of concentrates and 8.2% of either ordinary rice (control) or red yeast rice (RYR). Nutrient utilization was measured and enteric methane emissions were determined in respiration chambers...
2016: PloS One
J R B J Brouwers, J E Roeters van Lennep, A H E M Maas
- In various non-medical publications, red yeast rice (red fermented rice, RYR) is recommended as a cholesterol-lowering substance. This supplement contains a naturally occurring statin, namely monacolin K.- Patients who wish to use RYR should be advised to only take products from reputable pharmaceutical companies. Pharmacists can provide advice on this.- Users of RYR should be alerted to the potential drug interactions and serious risks associated with its use during pregnancy.- RYR appears to be better tolerated than statins...
2016: Nederlands Tijdschrift Voor Geneeskunde
Arrigo Francesco Giuseppe Cicero, Alessandro Colletti, Federica Fogacci, Marilisa Bove, Martina Rosticci, Claudio Borghi
BACKGROUND: There is an increasing interest for combined nutraceuticals that can act on several points of lipid and glucose metabolism with preventive purposes. However, the simple assemblage of nutraceuticals with potentially additive mechanism of action need to be clinically tested. METHODS: To assess the effects of a combination of nutraceuticals based on artichoke, red yeast rice, banaba, and coenzyme Q10, we performed a double bind, cross-over designed trial versus placebo in 30 adults with LDL cholesterol suboptimal in primary prevention of cardiovascular disease...
June 23, 2016: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
Elaine Marley, Phyllis Brown, Dave Leeman, Carol Donnelly
The analysis of citrinin in various cereals (wheat, oats, maize, rice, and rye and multigrain breakfast cereal), red yeast rice (dietary supplement and traditional medicine), distillers dried grain with solubles, and barley (animal feed) was carried out using a citrinin immunoaffinity column (IAC) for sample cleanup before LC analysis with fluorescence detection (LC-fluorescence). To establish method performance characteristics, wheat was spiked with citrinin at levels of 10-200 μg/kg, whereas red yeast rice was spiked at levels of 100-3000 μg/kg...
July 2016: Journal of AOAC International
Richard Glickman-Simon, Craig Schneider
No abstract text is available yet for this article.
July 2016: Explore: the Journal of Science and Healing
Yue Xiao, Qiongsi Zhang, Yiquan Luo, Ying Zhang, Xi Luo, Yuchuan Wang, Weiguo Cao, Vito De Pinto, Qiuyun Liu, Gang Li
Cellulases that endure extreme conditions are essential in various industrial sectors. This study reports a mini-cellulase gene tox-1 from Neurospora crassa. The gene tox-1 was cloned in Escherichia coli after chimerization with the YebF gene and substitutions of certain isoleucine and valine with leucine residues. The yeast transformants could grow on rice straw-agar medium. The 44-amino acid peptide and its two mutant variants displayed potent cellulase activities in Congo Red assay and enzymatic assays. Conservative replacements with leucine have substantially increased the stabilities and half-lives of the peptides at alkaline pH and low and high temperatures and also the tolerance to organic solvents and surfactants, on the basis of activities toward cellose...
June 15, 2016: Journal of Agricultural and Food Chemistry
Sumitra Govindarajan, Kishore Vellingiri
INTRODUCTION: Dietary supplements provide a novel population based health approach for treating hyperlipidemias. Red yeast rice is known to have lipid lowering effects. Combination of red yeast rice with various oils is taken by different population around the world. AIM: In this present work, we aimed to compare the effects of red yeast rice with different oil (coconut, rice bran and sunflower oil) supplementations on lipid levels and oxidative stress in rats fed on hypercholesterolemic diet...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
Arrigo F G Cicero, Martino Morbini, Marilisa Bove, Sergio D'Addato, Federica Fogacci, Martina Rosticci, Claudio Borghi
OBJECTIVE: The aim of our study was to evaluate the tolerability and efficacy of alternative approaches to improve cholesterolemia control in patients with statin-related myalgia treated with ezetimibe. RESEARCH DESIGN AND METHODS: We retrospectively evaluated 3534 Clinical Report Forms (CRFs) filled in the period June 2012-June 2015 for first visits to the lipid clinic of the University of Bologna. For this study, we selected 252 CRFs based on the following criteria: statin-related myalgia, previous failed treatment with at least two low-dosed statins, well-tolerated treatment with ezetimibe...
May 13, 2016: Current Medical Research and Opinion
Matteo Pirro, Massimo Raffaele Mannarino, Vanessa Bianconi, Luis E Simental-Mendía, Francesco Bagaglia, Elmo Mannarino, Amirhossein Sahebkar
Dyslipidemia and hyperglycemia are associated with an increased risk of ischemic cardiovascular disease. Positive effects of a nutraceutical combination comprising red yeast rice, berberine, policosanol, astaxanthin, coenzyme Q10 and folic acid (NComb) on plasma lipid and glucose levels have been reported in some but not all clinical trials. To address this inconsistency, we tried to estimate the size of lipid- and glucose-lowering effects of NComb through a systematic review and meta-analysis of randomized controlled trials...
August 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Ravi R Kasliwal, Manish Bansal, Rajeev Gupta, Siddharth Shah, Sameer Dani, Abraham Oomman, Vikas Pai, Guru Mallapa Prasad, Sunil Singhvi, Jitendra Patel, Sakthivel Sivam, Naresh Trehan
OBJECTIVE: Evidence suggests prolonged exposure to lower levels of low-density lipoprotein cholesterol (LDL-C), starting at a younger age, substantially lowers cardiovascular (CV) risk. Accordingly, the CV pandemic affecting younger population in low- to low-middle-income countries, where statin usage is poor even in secondary prevention, may benefit from lipid-lowering nutritional products, as nutritional intervention is generally preferred in these cultures. However, the safety and efficacy of such preparations have not been systematically tested...
July 2016: Nutrition
Jesus Millán, Arrigo F G Cicero, Francisco Torres, Anna Anguera
BACKGROUND AND AIM: A nutraceutical combination containing berberine, policosanol, and red yeast rice, largely marketed in Europe (Armolipid Plus(®)) (AP), has been reported to induce significant improvements in plasma lipids, insulin resistance and other components of the metabolic syndrome. However, literature study designs and results were heterogeneous and it was thus necessary to systematically review and meta-analyse all relevant randomised clinical trials (RCTs) to explore and quantify the effects of the dietary supplement AP on lipid profile...
July 2016: Clínica e Investigación en Arteriosclerosis
Dawei Zheng, Yi Wang, Yu Han, Jin-Rong Xu, Chenfang Wang
Rice false smut caused by Ustilaginoidea virens is one of the most important diseases of rice worldwide. Although its genome has been sequenced, to date there is no report on targeted gene deletion in U. virens and no molecular studies on genetic mechanisms regulating the infection processes of this destructive pathogen. In this study, we attempted to generate knockout mutants of the ortholog of yeast HOG1 MAP kinase gene in U. virens. One Uvhog1 deletion mutant was identified after screening over 600 hygromycin-resistant transformants generated by Agrobacterium tumefaciens mediated transformation...
2016: Scientific Reports
Pierre-Yves Rodondi, Florence Degoumois, Pedro Marques-Vidal, Nicolas Rodondi
Patients often use dietary supplements for cardiovascular prevention. An US study showed that 75% of patients with cardiovascular disease used dietary supplements. Red yeast rice, phytosterols and fibers can significantly decrease LDL. The level of monacolin in red yeast rice can vary between products and toxins can sometimes be found. Prospective studies showed that fibers could decrease cardiovascular risk. Others substances, like guggul, soy and artichoke leaf extracts, did not show a clear benefit for cardiovascular prevention...
March 2, 2016: Revue Médicale Suisse
Arrigo F G Cicero, Martino Morbini, Martina Rosticci, Sergio D''Addato, Elisa Grandi, Claudio Borghi
AIM: The aim of our study was to investigate whether treatment with red yeast rice added with Coenzyme Q10 is associated with changes in endothelial function and arterial stiffness. METHODS: This double blind, placebo-controlled, randomized clinical trial was carried out on 40 non-smoker moderately hypercholesterolemic subjects ( ID NCT02492464). After 4 weeks of diet and physical activity, patients were allocated to treatment with placebo or with an active product containing 10 mg monacolins and 30 mg Coenzyme Q10, to be assumed for 6 months...
2016: Annals of Nutrition & Metabolism
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