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https://www.readbyqxmd.com/read/29228098/association-of-household-opioid-availability-and-prescription-opioid-initiation-among-household-members
#1
Marissa J Seamans, Timothy S Carey, Daniel J Westreich, Stephen R Cole, Stephanie B Wheeler, G Caleb Alexander, Virginia Pate, M Alan Brookhart
Importance: Increases in prescription opioid use in the United States have been attributed to changing prescribing guidelines and attitudes toward pain relief; however, the spread of opioid use within households through drug diversion may also be a contributing factor. Objective: To investigate whether individuals living in a household with a prescription opioid user are more likely to initiate prescription opioids themselves, compared with individuals in households with a prescription nonsteroidal anti-inflammatory drug (NSAID) user...
December 11, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29227869/reliability-of-oscillometric-central-blood-pressure-responses-to-lower-limb-resistance-exercise
#2
Simon Fryer, Keeron Stone, Tabitha Dickson, James Faulkner, Danielle Lambrick, Pablo Corres, Lauren Jerred, Lee Stoner
BACKGROUND AND AIMS: Although it is well known that resistance training (RT) is beneficial for patients suffering from a variety of cardiovascular diseases, it remains underutilized as a rehabilitation tool as there is no reliable way to monitor the additional stress placed on the central organs. The current study aimed to determine between-day reliability of central haemodynamic indices using oscillometric pulse wave analysis (PWA) during progressive sub-maximal RT. METHODS: Nineteen healthy young males were tested on 3 different mornings in a fasted state...
December 5, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29227839/medical-marijuana-laws-and-adolescent-use-of-marijuana-and-other-substances-alcohol-cigarettes-prescription-drugs-and-other-illicit-drugs
#3
Magdalena Cerdá, Aaron L Sarvet, Melanie Wall, Tianshu Feng, Katherine M Keyes, Sandro Galea, Deborah S Hasin
BACKGROUND: Historical shifts have taken place in the last twenty years in marijuana policy. The impact of medical marijuana laws (MML) on use of substances other than marijuana is not well understood. We examined the relationship between state MML and use of marijuana, cigarettes, illicit drugs, nonmedical use of prescription opioids, amphetamines, and tranquilizers, as well as binge drinking. METHODS: Pre-post MML difference-in-difference analyses were performed on a nationally representative sample of adolescents in 48 contiguous U...
December 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29225909/improved-treatment-satisfaction-and-medication-adherence-after-readjusting-oral-medication-regimens-with-the-cooperation-of-health-insurance-pharmacy-in-type-2-diabetic-patients-in-japan
#4
Naoko Ogawa, Mitsuyoshi Takahara, Toshihiko Shiraiwa, Mayumi Yamamoto, Kaoru Yamamoto, Masayuki Doi, Yoko Yoshida, Setsuko Gotou
Background: Treatment satisfaction and medication adherence can be improved if physicians carefully monitor the situations, check the level of difficulties patients experience when taking medications at specific times, and readjust medication regimens based on this information. However, physicians in Japan encounter difficulties in taking enough time to collect this information in clinical practice. The aim of the current study was to investigate improvements in satisfaction and adherence with the cooperation of a health insurance pharmacy in clinical practice...
2017: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/29216902/improved-drug-safety-through-intensive-pharmacovigilance-in-hospitalized-pediatric-patients
#5
Alan O Vázquez-Alvarez, Lorena Michele Brennan-Bourdon, Ana Rosa Rincón-Sánchez, María Cristina Islas-Carbajal, Selene G Huerta-Olvera
BACKGROUND: The aim of this study was to detect and analyze Adverse Drug Reactions (ADRs) through Intensive Pharmacovigilance (IPV) in hospitalized pediatric patients to improve drug safety. METHODS: A prospective 6-month cross-sectional study was performed in the pediatric service of a regional hospital in Mexico in order to assess hospitalized children from 1 day to 18 years old. The inclusion criteria were: both genders, all hospitalization causes, and at least one prescribed medication (indistinct drug group)...
December 8, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29214743/gc-ms-ms-detects-potential-pregabalin-abuse-in-susceptible-subjects-hair
#6
Federica Ianni, Kyriaki Aroni, Alessio Gili, Roccaldo Sardella, Mauro Bacci, Massimo Lancia, Benedetto Natalini, Cristiana Gambelunghe
Pregabalin, a GABA analogue, binds to the alpha 2 delta subunit of voltage-dependent calcium channels. It is recognized as efficacious in pathologies such as epilepsy, neuropathic pain and anxiety disorders. Since pregabalin prescriptions have increased worldwide, reports of its abuse have been accumulating, mainly in patients with opioid abuse disorders. The present study investigated potential pregabalin abuse by means of hair analysis, a matrix that provides valuable retrospective information. Half of the pool of 280 susceptible patients had been occasional drug users and were being monitored for driving licence renewals...
December 7, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/29209229/proposal-of-a-global-training-load-measure-predicting-match-performance-in-an-elite-team-sport
#7
Brendan H Lazarus, Andrew M Stewart, Kevin M White, Amber E Rowell, Alireza Esmaeili, William G Hopkins, Robert J Aughey
Aim: The use of external and internal load is an important aspect of monitoring systems in team sport. The aim of this study was to validate a novel measure of training load by quantifying the training-performance relationship of elite Australian footballers. Methods: The primary training measure of each of 36 players was weekly load derived from a weighted combination of Global Positioning System (GPS) data and perceived wellness over a 24-week season. Smoothed loads representing an exponentially weighted rolling average were derived with decay time constants of 1...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29206984/rational-urine-drug-monitoring-in-patients-receiving-opioids-for-chronic-pain-consensus-recommendations
#8
Charles E Argoff, Daniel P Alford, Jeffrey Fudin, Jeremy A Adler, Matthew J Bair, Richard C Dart, Roy Gandolfi, Bill H McCarberg, Steven P Stanos, Jeffrey A Gudin, Rosemary C Polomano, Lynn R Webster
Objective: To develop consensus recommendations on urine drug monitoring (UDM) in patients with chronic pain who are prescribed opioids. Methods: An interdisciplinary group of clinicians with expertise in pain, substance use disorders, and primary care conducted virtual meetings to review relevant literature and existing guidelines and share their clinical experience in UDM before reaching consensus recommendations. Results: Definitive (e...
December 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29206708/use-of-a-telehealth-system-to-enhance-a-home-exercise-program-for-a-person-with-parkinson-disease-a-case-report
#9
Charlotte A Chatto, Paul T York, Catherine P Slade, Scott M Hasson
BACKGROUND AND PURPOSE: This case addresses feasibility of a home-based telehealth system to enhance home exercise program (HEP) adherence for a patient with Parkinson disease (PD). We describe START-System for Technology-Augmented Rehabilitation and Training-and discuss outcomes after integrating START into the HEP component of an established therapy protocol, Lee Silverman Voice Technique BIG (LSVT BIG). CASE DESCRIPTION: The participant was a 67-year-old woman with PD at Hoehn and Yahr Stage II...
December 1, 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29205442/palliative-care-for-end-of-life-patients-in-a-basic-emergency-service
#10
REVIEW
Maria Eduarda Diniz Pereira, António Barbosa, Maria Dos Anjos Dixe
This research sought to describe the care provided by the nursing staff of the Western Department of the Basic Emergency Service for end-of-life patients. This was a retrospective, quantitative, exploratory and descriptive (level I) study, which sought to research the nursing records of 83 patients from admission to death. Patients who met the following inclusion criteria were considered eligible: adults; had an oncological or nononcological, advanced and irreversible chronic disease; and died in the Basic Emergency Service in the period from January 2011 to December 2012...
December 5, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/29202489/-physician-pharmacist-communication-about-potentially-severe-drug-interactions
#11
Alexandra Pulst, Isabel Justus, Guido Schmiemann
Introduction Potentially serious drug interactions are often detected by pharmacists. In such cases fast communication with the General Practitioner (GP) is required. However, contacting physicians by telephone is often difficult. In a previous project a fax template was developed allowing fast communication of serious drug interactions to the GP. Utilization of the template and interactions detected were assessed in this observational study. Methods All pharmacists and GP in the city of Bremen were informed about the template...
December 4, 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29200879/cost-consequence-analysis-of-sitagliptin-versus-sulfonylureas-as-add-on-therapy-for-the-treatment-of-diabetic-patients-in-italy
#12
Valentina Lorenzoni, Fabio Baccetti, Stefano Genovese, Enrico Torre, Giuseppe Turchetti
Objective: Diabetes mellitus is a chronic disease related to a significant impact in both epidemiologic and economic terms. In Italy, around 3.6 million people are affected by diabetes and this number is expected to increase significantly in the next few years. As recommended by current national and international guidelines, metformin (Met) is prescribed as first-line pharmacological treatment, and many pharmacological alternatives are available for patients uncontrolled with Met monotherapy...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29200714/simultaneous-determination-of-ten-constituents-in-chaiqin-qingning-capsule-by-high-performance-liquid-chromatography-coupled-with-triple-quadrupole-mass-spectrometry
#13
Ting Yu Li, Xiao Kui Huo, Lu Zheng, Chao Wang, Hai Jian Cong, Ting Xiang, Lin Zhang, Bao Jing Zhang, Shan Shan Huang, Bin Wu, Xin Yu Li
Background: Chaiqin Qingning Capsule (CQQNC) was a prescription of Traditional Chinese Medicine with the effects of clearing away heat and removing toxin, harmonizing the exterior and interior, it was widely used in Asian, for example, China and Japan, different batches of the raws materials and different processing time may be the vital factor which raised a challenge to control the quality of the CQQNC. Experimental Methods: In this experiment, a high-performance liquid chromatography-mass spectrometry/MS (HPLC-MS/MS) method was developed to simultaneously determine ten bioactive components for the quality control of CQQNC...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29199394/trends-in-florida-s-prescription-drug-monitoring-program-registration-and-utilization-implications-for-increasing-voluntary-use
#14
Chris Delcher, Yanning Wang, Henry W Young, Bruce A Goldberger, Siegfried Schmidt, Gary M Reisfield
OBJECTIVE: Effective use of state prescription drug monitoring programs (PDMPs) to track controlled substance prescribing and dispensing may help mitigate the current opioid crisis. Our objective was to examine trends in registration for and use of Florida's PDMP by physicians and pharmacists, from 2013 to 2016. We discuss implications for PDMP uptake and policy. DESIGN: Key measures, such as cumulative number of registrants per license type and monthly utilization intensity, are presented...
September 2017: Journal of Opioid Management
https://www.readbyqxmd.com/read/29198878/medication-adherence-among-patients-with-gout-a-systematic-review-and-meta-analysis
#15
REVIEW
Lieke E J M Scheepers, Marloes van Onna, Coen D A Stehouwer, Jasvinder A Singh, Ilja C W Arts, Annelies Boonen
OBJECTIVE: In the management of chronic gout, a large proportion of patients need long-term management with urate lowering therapy (ULT). This study reviews medication adherence to ULT and summarizes factors associated with adherence. METHODS: We performed a systematic literature search for studies on adherence to ULT among gout patients in PubMed, Embase, CINAHL, and PsycINFO. We conducted meta-analysis, with a random effect model, for the studies reporting the proportion of patients considered adherent to at least 80% of prescribed medication or time taken...
October 7, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29198287/a-cross-sectional-examination-of-the-prevalence-of-psychotropic-medications-for-people-living-with-dementia-in-australian-long-term-care-facilities-issues-of-concern
#16
Mitchell McMaster, Elaine Fielding, David Lim, Wendy Moyle, Elizabeth Beattie
BACKGROUND: Behavioral and psychological symptoms of dementia (BPSD) are a common problem in long-term care facilities (LTC). Clinical guidelines dictate that first-line treatments for BPSD are psychosocial and behavioral interventions; if these are unsuccessful, psychotropic medications may be trialed at low doses and their effects can be monitored. METHODS: There have previously been no studies with nationally representative samples to investigate psychotropic administration in LTCs in Australia...
December 4, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29197326/potentially-inappropriate-prescriptions-for-elderly-people-taking-antidepressant-comparative-tools
#17
Izabela Fulone, Luciane Cruz Lopes
BACKGROUND: The use of psychotropic drugs by elderly people is widely spread around the world, given that prevalence of inappropriate medication is frequent. Strictly speaking, in Brazil, the vulnerable population of elderly people is more likely to use Potentially Inappropriate Psychotropic (PIP) due to the impact of social-economic characteristics, to the Brazilian Public Health System, and to the lack of patient monitoring. However, neither the use pattern nor the prevalence rate of PIP have been studied in Brazil so far...
December 2, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29192448/-simultaneous-determination-of-six-triterpenoid-acids-from-guizhi-fuling-capsules-by-uplc-ms-ms
#18
Ying Ma, Jia-Chun Li, Wen-Zhe Huang, Zhen-Zhong Wang, Wei Xiao, Ya-Ling Song, Yong-Wen Zhang
To establish a UPLC-MS/MS method for simultaneous determination of six triterpenoid constituents (pachymic acid, dehydropachymic acid, dehydrotumulosic acid, polyporenic acid C, dehydroeburicoic acid and dehydrotra metenolic acid) in Guizhi Fuling capsules (GFC). Chromatographic analysis was conducted on Agilent Porosheell 120 SB-C₁₈ column (4.6 mm×150 mm, 2.7 μm), with 0.1% formic acid aqueous solution-methanol as the mobile phase for gradient elution at a flow rate of 0.4 mL•min-1. The column temperature was 30 ℃ and the sample size was 5 μL...
September 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29186758/simultaneous-determination-of-multiple-classes-of-hydrophilic-and-lipophilic-components-in-shuang-huang-lian-oral-liquid-formulations-by-uplc-triple-quadrupole-linear-ion-trap-mass-spectrometry
#19
(no author information available yet)
The Shuang-Huang-Lian (SHL) oral liquid is a combined herbal prescription used in the treatment of acute upper respiratory tract infection, acute bronchitis and pneumonia. Multiple constituents are considered to be responsible for the therapeutic effects of SHL. However, the quantitation of the multi-components from multiple classes is still unsatisfactory because of the high complexity of constituents in SHL. In this study, an accurate, rapid, and specific UPLC-MS/MS method was established for simultaneous quantification of 18 compounds from multiple classes in SHL oral liquid formulations...
November 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29183067/prescription-drug-monitoring-programs-and-opioid-death-rates-reply
#20
Anne Schuchat, Gery P Guy, Deborah Dowell
No abstract text is available yet for this article.
November 28, 2017: JAMA: the Journal of the American Medical Association
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