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Mediterranean diet and weight loss

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https://www.readbyqxmd.com/read/29580835/implications-of-the-mediterranean-diet-and-physical-exercise-on-the-lipid-profile-of-metabolically-healthy-obese-women-as-measured-by-nuclear-magnetic-resonance-spectroscopy-1-h-nmr
#1
Enrique Rodriguez-Garcia, Josefina Ruiz-Nava, Sonia Santamaria-Fernandez, Jose Carlos Fernandez-Garcia, Antonio Vargas Candela, Raquel Yahyaoui, Francisco J Tinahones, M Rosa Bernal-Lopez, Ricardo Gomez-Huelgas
OBJECTIVE: There is a lack of consensus when it comes to establishing the biochemical parameters that define metabolically healthy obese (MHO) subjects. Indeed, most studies do not include subjects' lipid profiles. Our objective was to characterize lipoprotein size, particle and subclass concentration using1 H NMR in MHO women after two years of weight loss with a hypocaloric Mediterranean diet and physical exercise. METHODS: 115 non-diabetic women (aged 35-55 years) with a body mass index (BMI) of 30-40 kg/m2 and ≤1 of the following criteria: blood pressure ≥135/85 mmHg, fasting plasma glucose ≥100 mg/dL, HDL cholesterol ≤50 mg/dL and triglycerides ≥150 mg/dL were included...
March 23, 2018: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/29576369/the-effect-of-long-term-weight-loss-intervention-strategies-on-the-dynamics-of-pancreatic-fat-and-morphology-an-mri-rct-study
#2
Lilac Tene, Ilan Shelef, Dan Schwarzfuchs, Yftach Gepner, Anat Yaskolka Meir, Gal Tsaban, Hila Zelicha, Avital Bilitzky, Oded Komy, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Yoash Chassidim, Benjamin Sarusy, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Meir J Stampfer, Assaf Rudich, Iris Shai
BACKGROUND & AIMS: The ability to mobilize pancreatic-fat and the meaning of decreased fat in the pancreas remain controversial. We followed the dynamics of pancreatic-fat and its morphology during various long weight-loss induced lifestyle-interventions. METHODS: In isolated workplace with monitored/provided lunch, we randomly assigned healthy persons with abdominal obesity or dyslipidemia for one of two 18-month equal-caloric diets: low-fat (LF) or Mediterranean/low-carbohydrate (Med/LC, with provided 1oz walnuts/day), with or without added moderate exercise (supervised gym membership)...
April 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29543648/heart-rate-variability-a-biomarker-to-study-the-influence-of-nutrition-on-physiological-and-psychological-health
#3
Hayley A Young, David Benton
As the influence of diet on health may take place over a period of decades, there is a need for biomarkers that help to identify those aspects of nutrition that have either a positive or a negative influence. The evidence is considered that heart-rate variability (HRV) (the time differences between one beat and the next) can be used to indicate the potential health benefits of food items. Reduced HRV is associated with the development of numerous conditions for example, diabetes, cardiovascular disease, inflammation, obesity and psychiatric disorders...
April 2018: Behavioural Pharmacology
https://www.readbyqxmd.com/read/29492309/low-maternal-adherence-to-a-mediterranean-diet-is-associated-with-increase-in-methylation-at-the-meg3-ig-differentially-methylated-region-in-female-infants
#4
Sarah Gonzalez-Nahm, Michelle Mendez, Whitney Robinson, Susan K Murphy, Cathrine Hoyo, Vijaya Hogan, Diane Rowley
Diet is dictated by the surrounding environment, as food access and availability may change depending on where one lives. Maternal diet during pregnancy is an important part of the in utero environment, and may affect the epigenome. Studies looking at overall diet pattern in relation to DNA methylation have been lacking. The Mediterranean diet is known for its health benefits, including decreased inflammation, weight loss, and management of chronic diseases. This study assesses the association between maternal adherence to a Mediterranean diet pattern during pregnancy and infant DNA methylation at birth...
May 2017: Environmental Epigenetics
https://www.readbyqxmd.com/read/29483087/dietary-patterns-to-reduce-weight-and-optimize-cardiovascular-health-persuasive-evidence-for-promoting-multiple-healthful-approaches
#5
Cheryl A M Anderson
Healthful dietary patterns have a major role in healthy lifestyles and are necessary for cardiovascular health promotion.1 Over the past decade, dietary patterns have been a focus of human nutrition research studies. This is largely because of the well-recognized fact that we do not eat nutrients, we eat foods, and that we do not eat foods in isolation, we eat them in patterns. As a result, evidence is mounting on the effectiveness of multiple dietary patterns in reducing body weight2-4 and improving cardiovascular risk...
February 26, 2018: Circulation
https://www.readbyqxmd.com/read/29438460/practical-dietary-recommendations-for-the-prevention-and-management-of-nonalcoholic-fatty-liver-disease-in-adults
#6
Elena S George, Adrienne Forsyth, Catherine Itsiopoulos, Amanda J Nicoll, Marno Ryan, Siddharth Sood, Stuart K Roberts, Audrey C Tierney
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. In the absence of effective pharmacotherapies, clinical guidelines focus primarily on weight loss to treat this condition. Established consensus, evidence-based, and clinical dietary recommendations for NAFLD are currently lacking. The aim of this paper is to provide evidence-based practical dietary recommendations for the prevention and management of NAFLD in adults. A literature review focusing on established principles for the development of clinical practice recommendations was employed using the following criteria: based on substantial evidence, ensures risk minimization, is flexible for an individual patient approach, and is open to further modification as evidence emerges...
January 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29373032/tissue-level-diet-and-sex-by-diet-interactions-reveal-unique-metabolite-and-clustering-profiles-using-untargeted-liquid-chromatography-mass-spectrometry-on-adipose-skeletal-muscle-and-liver-tissue-in-c57bl6-j-mice
#7
Ann Wells, William T Barrington, Stephen Dearth, Amanda May, David W Threadgill, Shawn R Campagna, Brynn H Voy
Dietary intervention is commonly used for weight loss or to improve health, as diet-induced obesity increases risk of developing type 2 diabetes, hypertension, cardiovascular disease, stroke, osteoarthritis, and certain cancers. Various dietary patterns are associated with effects on health, yet little is known about the effects of diet at the tissue level. Using untargeted metabolomics, this study aimed to identify changes in water-soluble metabolites in C57BL/6J males and females, fed one of five diets (Japanese, ketogenic, Mediterranean, American, and standard mouse chow) for seven months...
January 26, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29218417/intensive-dietary-intervention-promoting-the-mediterranean-diet-in-people-with-high-cardiometabolic-risk-a-non-randomized-study
#8
M Grimaldi, O Ciano, M Manzo, M Rispoli, M Guglielmi, A Limardi, P Calatola, M Lucibello, S Pardo, B Capaldo, G Riccardi
AIMS: Mediterranean diet (MD) is acknowledged to exert a number of beneficial health effects. We assessed the efficacy and the durability of a 3-month intensive dietary intervention aimed at implementing the MD on body weight and cardiometabolic risk factors in subjects at high risk. METHODS: One hundred and sixteen subjects participated in the study (71 assigned to the intensive intervention and 45 to the conventional intervention). The intensive intervention consisted of 12 weekly group educational meetings and a free-of-charge supply of meals prepared according to the MD model...
March 2018: Acta Diabetologica
https://www.readbyqxmd.com/read/29198435/modifications-of-serum-levels-of-omentin-1-and-other-cardiovascular-risk-factors-following-weight-loss-secondary-to-a-mediterranean-hypocaloric-diet
#9
Daniel Antonio de Luis, Olatz Izaola, David Primo, R Aller
BACKGROUND & AIMS: Omentin-1 might play a role on insulin resistance, dyslipidemia and obesity. The aim of this investigation was to evaluate the influence of weight loss on omentin-1 concentrations after a hypocaloric diet with Mediterranean pattern. METHODS: A Caucasian sample of 67 obese patients was analyzed before and after 3 months on a hypocaloric diet. Anthropometric parameters, blood pressure, fasting blood glucose, C-reactive protein (CRP), fasting insulin, insulin resistance (HOMA-IR), lipid concentrations and omentin-1 were measured...
November 21, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29190720/intramyocellular-triacylglycerol-accumulation-across-weight-loss-strategies-sub-study-of-the-central-trial
#10
RANDOMIZED CONTROLLED TRIAL
Yftach Gepner, Ilan Shelef, Dan Schwarzfuchs, Noa Cohen, Nitzan Bril, Michal Rein, Gal Tsaban, Hila Zelicha, Anat Yaskolka Meir, Lilac Tene, Benjamin Sarusy, Philip Rosen, Jay R Hoffman, Jeffrey R Stout, Joachim Thiery, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Meir J Stampfer, Iris Shai
BACKGROUND: Intramyocellular triacylglycerol (IMTG) is utilized as metabolic fuel during exercise and is linked to insulin resistance, but the long-term effect of weight loss strategies on IMTG among participants with abdominal fat, remain unclear. METHODS: In an 18-month trial, sedentary participants with abdominal fat/dyslipidemia were randomized to either a low-fat (LF) or Mediterranean/low-carbohydrate (MED/LC) diet (including 28g·day-1 of walnuts). After 6-months, the participants were re-randomized to moderate intense physical activity (PA+) or non-physical activity (PA-)...
2017: PloS One
https://www.readbyqxmd.com/read/29154912/role-of-rs1501299-variant-in-the-adiponectin-gene-on-total-adiponectin-levels-insulin-resistance-and-weight-loss-after-a-mediterranean-hypocaloric-diet
#11
Daniel Antonio de Luis, Olatz Izaola, David Primo, Rocio Aller
BACKGROUND/AIM: Several adiponectin gene (ADIPOQ) single nucleotide polymorphisms (SNPS) have been related with adiponectin levels and risk for obesity. Our aim was to analyze the effects of rs1501299 ADIPOQ gene polymorphism on total adiponectin levels, insulin resistance and weight loss after a Mediterranean hypocaloric diet in obese subjects. METHODS: A Caucasian population of 82 obese patients was analyzed, before and after 3 months on a Mediterranean hypocaloric diet...
November 14, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29142011/effect-of-distinct-lifestyle-interventions-on-mobilization-of-fat-storage-pools-the-central-mri-randomized-controlled-trial
#12
Yftach Gepner, Ilan Shelef, Dan Schwarzfuchs, Hila Zelicha, Lilac Tene, Anat Yaskolka Meir, Gal Tsaban, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Oded Komy, Arik Wolak, Yoash Chassidim, Rachel Golan, Hilla Avni-Hassid, Avital Bilitzky, Benjamin Sarusi, Eyal Goshen, Elad Shemesh, Yaakov Henkin, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Uta Ceglarek, Assaf Rudich, Meir J Stampfer, Iris Shai
Background -We aimed to assess whether distinct lifestyle strategies can differentially affect specific body adipose depots. Methods -We performed an eighteen-month randomized controlled trial among 278 sedentary adults with abdominal obesity (75%) or dyslipidemia in an isolated workplace with a monitored provided lunch. Participants were randomized to iso-caloric low-fat (LF) or Mediterranean/low-carbohydrate (MED/LC) diet+28g walnuts/day with/without added moderate physical activity (PA;80% aerobic; supervised/free gym membership)...
November 15, 2017: Circulation
https://www.readbyqxmd.com/read/29136612/biochemical-anthropometric-and-lifestyle-factors-related-with-weight-maintenance-after-weight-loss-secondary-to-a-hypocaloric-mediterranean-diet
#13
Daniel Antonio de Luis, Olatz Izaola, David Primo, Hilda F Ovalle, Juan Jose Lopez, Emilia Gomez, Ana Ortola, Rocio Aller
BACKGROUND/AIMS: The aim of our study was to evaluate the influence of lifestyle factors and molecular biomarkers on the maintenance of the weight lost after a hypocaloric Mediterranean diet. DESIGN: After 3 months on a diet, patients (n = 335) remained with no controlled diet during 3 years and they were revaluated. RESULTS: Using linear regression, in the group of responders, we detected that a positive weight loss at 3 months, serum levels of leptin at 3 months, and each 30 min per week of physical activity were associated with weight loss maintenance...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28937599/mediterranean-diet-and-multi-ingredient-based-interventions-for-the-management-of-non-alcoholic-fatty-liver-disease
#14
REVIEW
Manuel Suárez, Noemí Boqué, Josep M Del Bas, Jordi Mayneris-Perxachs, Lluís Arola, Antoni Caimari
Non-alcoholic fatty liver disease (NAFLD) comprises a wide spectrum of hepatic disorders, from simple steatosis to hepatic necro-inflammation leading to non-alcoholic steatohepatitis (NASH). Although the prevalence of these multifactorial pathologies is continuously increasing in the population, there is still not an established methodology for their treatment other than weight loss and a change in lifestyle habits, such as a hypocaloric diet and physical exercise. In this framework, there is increasing evidence that several food bioactives and dietary patterns are effective for reversing and preventing the onset of these pathologies...
September 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28933748/dietary-composition-independent-of-weight-loss-in-the-management-of-non-alcoholic-fatty-liver-disease
#15
REVIEW
Tannaz Eslamparast, Puneeta Tandon, Maitreyi Raman
Poor dietary composition is an important factor in the progression of non-alcoholic fatty liver disease (NAFLD). The majority of NAFLD patients follow diets with overconsumption of simple carbohydrates, total and saturated fat, with reduced intake of dietary fiber and omega-3 rich foods. Although lifestyle modifications including weight loss and exercise remain the keystone of NAFLD management, modifying dietary composition with or without a calorie-restricted diet may also be a feasible and sustainable strategy for NAFLD treatment...
July 26, 2017: Nutrients
https://www.readbyqxmd.com/read/28919065/metabolically-healthy-obesity-the-low-hanging-fruit-in-obesity-treatment
#16
REVIEW
Norbert Stefan, Hans-Ulrich Häring, Matthias B Schulze
Obesity increases the risk of several other chronic diseases and, because of its epidemic proportions, has become a major public health problem worldwide. Alarmingly, a lower proportion of adults have tried to lose weight during the past decade than during the mid-1980s to 1990s. The first-line treatment option for obesity is lifestyle intervention. Although this approach can decrease fat mass in the short term, these beneficial effects typically do not persist. If a large amount of weight loss is not an easily achievable goal, other goals that might motivate people with obesity to adopt a healthy lifestyle should be considered...
September 14, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28918168/adherence-to-a-mediterranean-diet-is-associated-with-lower-incidence-of-frailty-a-longitudinal-cohort-study
#17
Nicola Veronese, Brendon Stubbs, Marianna Noale, Marco Solmi, Renè Rizzoli, Alberto Vaona, Jacopo Demurtas, Gaetano Crepaldi, Stefania Maggi
BACKGROUND & AIMS: There is a paucity of data investigating the relationship between the Mediterranean diet and frailty, with no data among North American people. We aimed to investigate if adherence to a Mediterranean diet is associated with a lower incidence of frailty in a large cohort of North American people. METHODS: This study included subjects at higher risk or having knee osteoarthritis. Adherence to the Mediterranean diet was evaluated using a validated Mediterranean diet score (aMED) as proposed by Panagiotakos and classified into five categories...
September 4, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28874313/new-therapeutic-perspectives-in-non-alcoholic-steatohepatitis
#18
Javier Ampuero, Yolanda Sánchez-Torrijos, Virginia Aguilera, Francisco Bellido, Manuel Romero-Gómez
Management of non-alcoholic steatohepatitis is focused on restitution of metabolic derangement, weight loss and drugs able to improve steatosis, ballooning and fibrosis. Life-style interventions based on Mediterranean diet and increasing physical activity are the first line therapy. In patients with unsuccessful life-style intervention several drugs are under development: agonist PPAR, agonist GLP-1R and agonist FXR together with drugs focussing on inflammation, ballooning, apoptosis and fibrosis. Bariatric surgery or advanced endoscopy are reserved for morbid obese without response to life-style intervention and weighting loss drugs...
September 2, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28869073/association-of-the-rs10830963-polymorphism-in-melatonin-receptor-type-1b-mtnr1b-with-metabolic-response-after-weight-loss-secondary-to-a-hypocaloric-diet-based-in-mediterranean-style
#19
Daniel Antonio de Luis, Olatz Izaola, David Primo, R Aller
BACKGROUND & AIMS: Some genetic variants within MTNR1B were related with fasting glucose levels or the increased prevalence of diabetes mellitus and obesity. The aims of the present investigation were to determine the influence of rs10830963 MTNR1B variant in relation to body weight loss, insulin resistance and adipokine levels in response to a hypocaloric diet with Mediterranean pattern. METHODS: A Caucasian population of 80 obese patients was studied before and after 12 weeks on a hypocaloric diet...
August 23, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28814394/dynamics-of-intrapericardial-and-extrapericardial-fat-tissues-during-long-term-dietary-induced-moderate-weight-loss
#20
COMPARATIVE STUDY
Gal Tsaban, Arik Wolak, Hila Avni-Hassid, Yftach Gepner, Ilan Shelef, Yaakov Henkin, Dan Schwarzfuchs, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Lilac Tene, Hila Zelicha, Anat Yaskolka-Meir, Oded Komy, Avital Bilitzky, Yoash Chassidim, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Dror Dicker, Assaf Rudich, Meir J Stampfer, Iris Shai
Background: In view of evidence linking pericardial fat accumulation with increased cardiovascular disease risk, strategies to reduce its burden are needed. Data comparing the effects of specific long-term dietary interventions on pericardial fat tissue mobilization are sparse.Objective: We sought to evaluate intrapericardial-fat (IPF) and extrapericardial-fat (EPF) changes during weight-loss interventions by different dietary regimens.Design: During 18 mo of a randomized controlled trial, we compared a Mediterranean/low-carbohydrate (MED/LC) diet plus 28 g walnuts/d with a calorically equal low-fat (LF) diet among randomly assigned participants with moderate abdominal obesity...
October 2017: American Journal of Clinical Nutrition
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