keyword
https://read.qxmd.com/read/38537153/novel-proteomic-signatures-may-indicate-mri-assessed-intrahepatic-fat-state-and-changes-the-direct-plus-clinical-trial
#1
JOURNAL ARTICLE
Dana T Goldberg, Anat Yaskolka Meir, Gal Tsaban, Ehud Rinott, Alon Kaplan, Hila Zelicha, Nora Klöting, Uta Ceglarek, Berend Iserman, Ilan Shelef, Philip Rosen, Matthias Blüher, Michael Stumvoll, Ohad Etzion, Meir J Stampfer, Frank B Hu, Iris Shai
OBJECTIVE: We demonstrated in the randomized 18-month DIRECT PLUS trial (n=294) that a Mediterranean (MED) diet, supplemented with polyphenol-rich Mankai duckweed, green tea, and walnuts and restricted in red/processed meat, caused substantial intrahepatic fat (IHF%) loss compared with two other healthy diets, reducing NAFLD by half, regardless similar weight loss. Here, we investigated the baseline proteomic profile associated with IHF% and the changes in proteomics associated with IHF% changes induced by lifestyle intervention...
March 27, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38533958/associations-of-alcohol-consumption-with-left-atrial-morphology-and-function-in-a-population-at-high-cardiovascular-risk
#2
JOURNAL ARTICLE
Aniqa B Alam, Estefania Toledo-Atucha, Dora Romaguera, Angel M Alonso-Gómez, Miguel A Martínez-Gonzalez, Lucas Tojal-Sierra, Marta Noris Mora, Caterina Mas-Llado, Linzi Li, Ines Gonzalez-Casanova, Jordi Salas-Salvadó, Montserrat Fitó, Alvaro Alonso
BACKGROUND: Excessive alcohol consumption has been associated with increased risk of atrial fibrillation, although the underlying mechanisms remain unclear. An enlarged left atrium and impaired left atrial function may lead to atrial fibrillation. The association of alcohol consumption with structural and functional left atrial measures, however, has received limited attention. METHODS AND RESULTS: We studied 503 participants from the PREDIMED-Plus (Prevención con Dieta Mediterránea) trial, a randomized trial testing intensive weight loss intervention with an energy-reduced Mediterranean diet and physical activity promotion in preventing cardiovascular disease in adults with metabolic syndrome...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38522851/-dietary-management-of-obesity
#3
REVIEW
Sang Hoon Lee, San Ha Kim, Sung Chul Park
Obesity is defined as a condition characterized by the abnormal accumulation of fat cells, which results in increased body weight. Worldwide, obesity is progressively on the rise, leading to an increased prevalence of chronic conditions such as cardiovascular disease, type 2 diabetes, and hyperlipidemia. Obesity is a result of the interplay between genetic, metabolic, social, behavioral, and cultural factors, necessitating an interdisciplinary and multimodal management approach. Diet therapy, which includes dietary modifications and nutritional interventions, is a fundamental component of the multifaceted approach to managing obesity...
March 25, 2024: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://read.qxmd.com/read/38499938/dysbiosis-and-nutrition-in-steatotic-liver-disease-addressing-the-unrecognized-small-intestinal-bacterial-overgrowth-sibo-challenge
#4
REVIEW
Ewa Stachowska, Anna Gudan, Dorota Mańkowska-Wierzbicka, Roman Liebe, Marcin Krawczyk
Steatotic liver disease (SLD) is characterized by hepatic fat accumulation, potentially causing major consequences such as liver decompensation. Currently, we lack medications for the treatment of SLD. Therapeutic recommendations for patients include a hypocaloric diet, weight loss, and physical activity. In particular, the Mediterranean diet is frequently recommended. However, this diet might exacerbate intestinal problems in a subset of patients with coexisting small intestinal bacterial overgrowth (SIBO)...
March 18, 2024: Internal and Emergency Medicine
https://read.qxmd.com/read/38459161/mediterranean-style-dietary-interventions-in-adults-with-cancer-a-systematic-review-of-the-methodological-approaches-feasibility-and-preliminary-efficacy
#5
REVIEW
Aoife McHugh, Ellie O'Connell, Bridie Gurd, Paige Rae, Elena S George, Amber S Kleckner, Brenton J Baguley
BACKGROUND: Cancer and its treatments can lead to excess body fat, decreases in lean mass, cardiotoxicity, and other side effects. The Mediterranean diet (MED-diet) has the potential to improve clinical and supportive care outcomes. The aim of this systematic review was to evaluate the feasibility, safety, and efficacy of the MED-diet on health outcomes in adults with cancer. METHODS: Three databases were searched from inception to February 2023. Eligible studies included randomised controlled trials testing a MED-diet intervention among adults with cancer...
March 8, 2024: European Journal of Clinical Nutrition
https://read.qxmd.com/read/38428742/effect-of-1-year-lifestyle-intervention-with-energy-reduced-mediterranean-diet-and-physical-activity-promotion-on-the-gut-metabolome-and-microbiota-a-randomized-clinical-trial
#6
JOURNAL ARTICLE
Jesús F García-Gavilán, Alessandro Atzeni, Nancy Babio, Liming Liang, Clara Belzer, Jesús Vioque, Dolores Corella, Montserrat Fitó, Josep Vidal, Isabel Moreno-Indias, Laura Torres-Collado, Oscar Coltell, Estefanía Toledo, Clary Clish, Javier Hernando, Huan Yun, Adrián Hernández-Cacho, Sarah Jeanfavre, Courtney Dennis, Ana M Gómez-Pérez, Maria Angeles Martínez, Miguel Ruiz Canela, Francisco J Tinahones, Frank B Hu, Jordi Salas-Salvadó
BACKGROUND: The health benefits of the Mediterranean diet (MedDiet) have been linked to the presence of beneficial gut microbes and related metabolites. However, its impact on the fecal metabolome remains poorly understood. OBJECTIVE: Our goal was to investigate the weight loss effects of a 1-year lifestyle intervention based on an energy-reduced MedDiet coupled with physical activity (intervention group), compared to an ad libitum MedDiet (control group), on fecal metabolites, fecal microbiota, and their potential association with cardiovascular risk factors METHODS: A total of 400 participants (200 from each study group), aged 55-75 years, and at high cardiovascular risk, were included...
February 28, 2024: American Journal of Clinical Nutrition
https://read.qxmd.com/read/38411795/bariatric-nutritional-intervention-in-obese-patients-with-compensated-liver-cirrhosis-a-four-year-prospective-study
#7
JOURNAL ARTICLE
Zacharias E Kalaitzakis, Emmanuel Giahnakis, Ioannis E Koutroubakis, Ioannis A Mouzas, Evangelos Kalaitzakis
BACKGROUND: Obesity and liver cirrhosis represent significant health challenges, often leading to various complications. AIMS: This prospective study aimed to investigate the impact of a four-year bariatric intervention, focusing on adherence to the Mediterranean Diet, on anthropometric, hematologic, and biochemical parameters in obese patients with compensated liver cirrhosis. Additionally, the study evaluated the concurrent contribution of weight loss to these health indicators...
February 27, 2024: Digestive Diseases and Sciences
https://read.qxmd.com/read/38385102/practical-lifestyle-management-of-nonalcoholic-fatty-liver-disease-for-busy-clinicians
#8
JOURNAL ARTICLE
Shira Zelber-Sagi, J Bernadette Moore
Weight loss achieved through a combination of healthy eating patterns that encompass the principles of the Mediterranean diet and regular physical activity is the most evidence-based treatment for nonalcoholic fatty liver disease. Although other types of diets have demonstrated efficacy in liver fat reduction, the Mediterranean diet confers additional cardiometabolic benefits. Macronutrient composition, food choices, and timing of eating can be tailored to individual preferences, culture, and financial circumstances; however, recommended healthy eating patterns are characterized by minimally processed or unprocessed foods (vegetables, legumes, nuts and seeds, fruits, whole grains, and unprocessed meats and fish) that are low in sugar, refined carbohydrates, and saturated fat and high in fiber, polyphenols, vitamins, minerals, and healthy fats...
2024: Diabetes Spectrum: a Publication of the American Diabetes Association
https://read.qxmd.com/read/38370054/evaluation-of-the-effect-of-gluten-free-diet-and-mediterranean-diet-on-autoimmune-system-in-patients-with-hashimoto-s-thyroiditis
#9
JOURNAL ARTICLE
Mutlu Tuçe Ülker, Gözde Arıtıcı Çolak, Murat Baş, Mustafa Genco Erdem
Hashimoto's thyroiditis is an autoimmune disease in which thyroid cells are attacked through cell-and antibody-mediated immune processes. A gluten-free diet reduces antibody concentration and regulates thyroid autoimmunization. Mediterranean diet reduces oxidative stress. This study evaluates the short-term effects of Mediterranean, gluten-free, and Mediterranean gluten-free dietary patterns on thyroid function and autoantibody levels of patients. The 40 patients with Hashimoto's thyroiditis included in the study were randomly divided into four groups (defined as gluten-free, Mediterranean, Mediterranean gluten-free, and controls) for 12 weeks...
February 2024: Food Science & Nutrition
https://read.qxmd.com/read/38324396/nutritional-interventions-as-modulators-of-the-disease-activity-for-idiopathic-inflammatory-myopathies-a-scoping-review
#10
JOURNAL ARTICLE
Abril I Sánchez-Rosales, Juan G Posadas-Calleja, Aurora E Serralde-Zúñiga, Gabriela Quiroz-Olguín
Idiopathic inflammatory myopathies (IIMs) are chronic, autoimmune connective tissue diseases associated with significant morbidity and disability. Nutrients can activate the immune system and contribute to chronic low-grade inflammation (LGI). Chronic muscle inflammation leads to imbalanced pro-inflammatory and anti-inflammatory cytokines, causing inadequate nutrition, weight loss and muscle weakness during a negative cycle. Owing to its potential to modulate LGI in various diseases, the Mediterranean diet (Med Diet) has been extensively studied...
February 7, 2024: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://read.qxmd.com/read/38310558/dietary-effects-of-fasting-on-the-lipid-panel
#11
JOURNAL ARTICLE
Jason Hourizadeh, Rezwan Munshi, Roman Zeltser, Amgad Makaryus
INTRODUCTION: Dietary habits, such as the Mediterranean diet and the Dietary Approaches to Stop Hypertension (DASH), have been shown to improve cardiac health. METHOD: Another more recent popular form of dieting incorporates periods of fasting known as intermittent fasting. The two main forms are alternate-day fasting and time-restricted eating. RESULT: There have been studies that have shown that intermittent fasting does provide a benefit in cardiovascular health, weight loss, and hypertension...
January 9, 2024: Current Cardiology Reviews
https://read.qxmd.com/read/38279337/the-impact-of-the-mediterranean-diet-and-lifestyle-intervention-on-lipoprotein-subclass-profiles-among-metabolic-syndrome-patients-findings-of-a-randomized-controlled-trial
#12
JOURNAL ARTICLE
Beatriz Candás-Estébanez, Bárbara Fernández-Cidón, Emili Corbella, Cristian Tebé, Marta Fanlo-Maresma, Virginia Esteve-Luque, Jordi Salas-Salvadó, Montserrat Fitó, Antoni Riera-Mestre, Emilio Ros, Xavier Pintó
Metabolic syndrome (MetS) is associated with alterations of lipoprotein structure and function that can be characterized with advanced lipoprotein testing (ADLT). The effect of the Mediterranean diet (MedDiet) and weight loss on the lipoprotein subclass profile has been scarcely studied. Within the PREDIMED-Plus randomized controlled trial, a sub-study conducted at Bellvitge Hospital recruiting center evaluated the effects of a weight loss program based on an energy-reduced MedDiet (er-MedDiet) and physical activity (PA) promotion (intervention group) compared with energy-unrestricted MedDiet recommendations (control group) on ADLT-assessed lipoprotein subclasses...
January 22, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38278641/pairing-evidence-based-strategies-with-motivational-interviewing-to-support-optimal-nutrition-and-weight-gain-in-pregnancy
#13
JOURNAL ARTICLE
Cecilia M Jevitt, Kiley Ketchum
OBJECTIVE: Because eating, nutrition, and weight management patterns adopted during pregnancy may persist beyond the postpartum period, pregnancy provides an opportunity for health education that affects the future health of the pregnant person, the fetus, and the family. This systematic review aimed to find nutrition and weight management behaviors that could be used safely during pregnancy to optimize gestational weight gain. METHODS: PubMed, MEDLINE, and Web of Science were searched for research or systematic reviews published in English from 2018 to 2023 using terms including gestational weight gain maintenance, weight, management, pregnancy, behavior, strategy, and strategies...
January 2024: Journal of Perinatal & Neonatal Nursing
https://read.qxmd.com/read/38276922/aga-clinical-practice-update-on-diet-and-nutritional-therapies-in-patients-with-inflammatory-bowel-disease-expert-review
#14
Jana G Hashash, Jaclyn Elkins, James D Lewis, David G Binion
DESCRIPTION: Diet plays a critical role in human health, but especially for patients with inflammatory bowel disease (IBD). Guidance about diet for patients with IBD are often controversial and a source of uncertainty for many physicians and patients. The role of diet has been investigated as a risk factor for IBD etiopathogenesis and as a therapy for active disease. Dietary restrictions, along with the clinical complications of IBD, can result in malnutrition, an underrecognized condition among this patient population...
January 23, 2024: Gastroenterology
https://read.qxmd.com/read/38276803/evidence-based-eating-patterns-and-behavior-changes-to-limit-excessive-gestational-weight-gain-a-scoping-review
#15
REVIEW
Kiley Ketchum, Cecilia M Jevitt
BACKGROUND: International prenatal care guidelines set a standard for clinicians to discuss gestational weight gain with their patients along with the complications associated with prepregnancy obesity and excessive gestational weight gain. Clinicians often lack evidence-based eating, nutrition, and activity strategies to share with patients. METHODS: This systematic review aimed to find eating patterns and behaviors that could be used safely during pregnancy to limit excessive gestational weight gain...
December 21, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38275650/telomere-maintenance-is-associated-with-type-2-diabetes-remission-in-response-to-a-long-term-dietary-intervention-without-non-weight-loss-in-patients-with-coronary-heart-disease-from-the-cordioprev-randomized-controlled-trial
#16
JOURNAL ARTICLE
Ana Ojeda-Rodriguez, Juan F Alcala-Diaz, Oriol Alberto Rangel-Zuñiga, Antonio P Arenas-de Larriva, Francisco M Gutierrez-Mariscal, Jose D Torres-Peña, Marina Mora-Ortiz, Juan L Romero-Cabrera, Raul M Luque, Jose M Ordovas, Pablo Perez-Martinez, Javier Delgado-Lista, Elena M Yubero-Serrano, Jose Lopez-Miranda
In order to evaluate whether telomere maintenance is associated with type 2 diabetes remission, newly diagnosed type 2 diabetes patients without glucose-lowering treatment (183 out of 1002) from the CORDIOPREV study (NCT00924937) were randomized to consume a Mediterranean or low-fat diet. Patients were classified as Responders, those who reverted from type 2 diabetes during the 5 years of dietary intervention ( n = 69), and Non-Responders, who did not achieve diabetes remission by the end of the follow-up period ( n = 104)...
January 19, 2024: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/38267386/body-size-diet-quality-and-epigenetic-ageing-cross-sectional-and-longitudinal-analyses
#17
JOURNAL ARTICLE
Danmeng Lily Li, Allison M Hodge, Lachlan Cribb, Melissa C Southey, Graham G Giles, Roger L Milne, Pierre-Antoine Dugué
Epigenetic age is an emerging marker of health that is highly predictive of disease and mortality risk. There is a lack of evidence on whether lifestyle changes are associated with changes in epigenetic ageing. We used data from 1,041 participants in the Melbourne Collaborative Cohort Study with blood DNA methylation measures at baseline (1990-1994, mean age: 57.4 years) and follow-up (2003-2007, mean age: 68.8 years). The Alternative Healthy Eating Index-2010 (AHEI-2010), the Mediterranean Dietary Score and the Dietary Inflammatory Index were used as measures of diet quality, and weight, waist circumference and waist-to-hip ratio as measures of body size...
January 24, 2024: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://read.qxmd.com/read/38263989/mediterranean-diet-intervention-among-world-trade-center-responders-with-post-traumatic-stress-disorder-feasibility-and-outcomes-of-a-pilot-randomized-controlled-trial
#18
JOURNAL ARTICLE
Chrisa Arcan, Wei Hou, Kathryn Hoffman, Amanda Reichardt, Xiaohua Yang, Sean A P Clouston, Evelyn J Bromet, Benjamin Luft
OBJECTIVE: Responders of the World Trade Center (WTC) disaster suffer from co-morbidities. A Mediterranean Diet (MedDiet) nutrition intervention with physical activity was implemented among WTC responders with overweight/obesity and post-traumatic stress disorder (PTSD). METHODS: WTC Health Program members ( N  = 62), 45-65 years, males 87%, body mass index (BMI) 27-45 kg/m2 randomized to MedDiet ( n  = 31) or usual nutrition counseling ( n  = 31)...
February 2024: Obesity Science & Practice
https://read.qxmd.com/read/38262842/dietary-and-pharmacological-treatment-in-patients-with-metabolic-dysfunction-associated-steatotic-liver-disease
#19
REVIEW
Angelo Armandi, Elisabetta Bugianesi
Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD) is a disease spectrum encompassing liver injury with progressive severity, tightly connected to the metabolic syndrome. Management of MASLD mostly relies on lifestyle change aiming at improving metabolic homeostasis and insulin resistance. A Mediterranean-like dietary pattern and individualized lifestyle interventions are the cornerstone of MASLD treatment. A careful evaluation of alcohol intake and active treatment of all metabolic co-morbidities are recommended...
January 22, 2024: European Journal of Internal Medicine
https://read.qxmd.com/read/38261251/nutritional-aspects-to-cardiovascular-diseases-and-type-2-diabetes-mellitus
#20
REVIEW
Hayley E Billingsley, Emily M Heiston, Moriah P Bellissimo, Carl J Lavie, Salvatore Carbone
PURPOSE OF REVIEW: In this narrative review, we discuss the current evidence related to the role of dietary interventions to prevent and treat type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). We also propose alternative therapeutic strategies other than weight loss in this population, namely, improvements in cardiorespiratory fitness and its determinants. RECENT FINDINGS: While weight loss has been consistently associated with the prevention of T2DM and improvements in glycemic control in those with established diseases, its role in preventing and treating CVD is less clear...
January 23, 2024: Current Cardiology Reports
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