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Mediterranean diet and weight loss

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https://www.readbyqxmd.com/read/29877711/impact-in-plasma-metabolome-as-effect-of-a-lifestyle-intervention-for-weight-loss-reveal-metabolic-benefits-in-metabolically-healthy-obese-women
#1
Enrique Almanza-Aguilera, Carl Brunius, M Rosa Bernal-Lopez, Mar Garcia-Aloy, Francisco Madrid-Gambin, Francisco J Tinahones, Ricardo Gómez-Huelgas, Rikard Landberg, Cristina Andres-Lacueva
Little is known regarding metabolic benefits of weight loss (WL) on the metabolically healthy obese (MHO) patients. We aimed to examine the impact of a lifestyle weight loss (LWL) treatment on the plasma metabolomic profile in MHO individuals. Plasma samples from 57 MHO women allocated to an intensive LWL treatment group (TG, hypocaloric Mediterranean diet and regular physical activity, n = 30) or to a control group (CG, general recommendations of a healthy diet and physical activity, n = 27) were analysed using an untargeted 1H-NMR metabolomics approach at baseline, after 3 months (intervention) and 12 months (follow-up)...
June 7, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29859275/role-of-rs670-variant-of-apoa1-gene-on-lipid-profile-insulin-resistance-and-adipokine-levels-in-obese-subjects-after-weight-loss-with-a-dietary-intervention
#2
Daniel Antonio de Luis, Olatz Izaola, David Primo, R Aller
OBJECTIVE: The aim of this study was to analyze the effects of rs670 APOA1 gene polymorphism on obesity parameters, lipid profile, glucose metabolism markers, blood pressure and adipokine levels after a hypocaloric diet with Mediterranean pattern. MATERIAL AND METHODS: A population of 82 obese patients was studied before and after 12 weeks on a hypocaloric diet (500 kcal per day) in an interventional study of one arm. GG and GA+AA subjects receiving the same diet...
May 30, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29729189/ad-libitum-mediterranean-and-low-fat-diets-both-significantly-reduce-hepatic-steatosis-a-randomized-controlled-trial
#3
Catherine Properzi, Therese A O'Sullivan, Jill L Sherriff, Helena L Ching, Garry P Jeffrey, Rachel F Buckley, Jonathan Tibballs, Gerry C MacQuillan, George Garas, Leon A Adams
Although diet induced weight loss is first-line treatment for patients with non-alcoholic fatty liver disease (NAFLD), long-term maintenance is difficult. The optimal diet for either improvement in NAFLD or associated cardio-metabolic risk factors regardless of weight loss, is unknown. We examined the effect of two ad libitum isocaloric diets [Mediterranean (MD) or Low Fat (LF)] on hepatic steatosis and cardio-metabolic risk factors. Subjects with NAFLD were randomized to a 12-week blinded dietary intervention (MD vs LF)...
May 5, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29722845/mediterranean-diet-and-risk-of-frailty-syndrome-among-women-with-type-2-diabetes
#4
Esther Lopez-Garcia, Kaitlin A Hagan, Teresa T Fung, Frank B Hu, Fernando Rodríguez-Artalejo
Background: Previous research indicates that patients with type 2 diabetes are at higher risk of becoming frail. Emerging evidence also indicates that the Mediterranean diet may prevent frailty in the older population. Objective: The aim of this study was to assess whether a Mediterranean-style diet pattern was associated with lower risk of frailty among older women with diabetes. Design: This was a prospective cohort study in 8970 women aged ≥60 y with type 2 diabetes from the Nurses' Health Study...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29710160/vegetarian-and-mediterranean-diets-effective-for-weight-loss
#5
Anita Slomski
No abstract text is available yet for this article.
April 24, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29580835/implications-of-the-mediterranean-diet-and-physical-exercise-on-the-lipid-profile-of-metabolically-healthy-obese-women-as-measured-by-nuclear-magnetic-resonance-spectroscopy-1-h-nmr
#6
Enrique Rodriguez-Garcia, Josefina Ruiz-Nava, Sonia Santamaria-Fernandez, Jose Carlos Fernandez-Garcia, Antonio Vargas-Candela, Raquel Yahyaoui, Francisco J Tinahones, M Rosa Bernal-Lopez, Ricardo Gomez-Huelgas
OBJECTIVE: There is a lack of consensus when it comes to establishing the biochemical parameters that define metabolically healthy obese (MHO) subjects. Indeed, most studies do not include subjects' lipid profiles. Our objective was to characterize lipoprotein size, particle and subclass concentration using 1 H NMR in MHO women after two years of weight loss with a hypocaloric Mediterranean diet and physical exercise. METHODS: 115 non-diabetic women (aged 35-55 years) with a body mass index (BMI) of 30-40 kg/m2 and ≤1 of the following criteria: blood pressure ≥135/85 mmHg, fasting plasma glucose ≥100 mg/dL, HDL cholesterol ≤50 mg/dL and triglycerides ≥150 mg/dL were included...
July 2018: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/29576369/the-effect-of-long-term-weight-loss-intervention-strategies-on-the-dynamics-of-pancreatic-fat-and-morphology-an-mri-rct-study
#7
Lilac Tene, Ilan Shelef, Dan Schwarzfuchs, Yftach Gepner, Anat Yaskolka Meir, Gal Tsaban, Hila Zelicha, Avital Bilitzky, Oded Komy, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Yoash Chassidim, Benjamin Sarusy, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Meir J Stampfer, Assaf Rudich, Iris Shai
BACKGROUND & AIMS: The ability to mobilize pancreatic-fat and the meaning of decreased fat in the pancreas remain controversial. We followed the dynamics of pancreatic-fat and its morphology during various long weight-loss induced lifestyle-interventions. METHODS: In isolated workplace with monitored/provided lunch, we randomly assigned healthy persons with abdominal obesity or dyslipidemia for one of two 18-month equal-caloric diets: low-fat (LF) or Mediterranean/low-carbohydrate (Med/LC, with provided 1oz walnuts/day), with or without added moderate exercise (supervised gym membership)...
April 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29543648/heart-rate-variability-a-biomarker-to-study-the-influence-of-nutrition-on-physiological-and-psychological-health
#8
Hayley A Young, David Benton
As the influence of diet on health may take place over a period of decades, there is a need for biomarkers that help to identify those aspects of nutrition that have either a positive or a negative influence. The evidence is considered that heart-rate variability (HRV) (the time differences between one beat and the next) can be used to indicate the potential health benefits of food items. Reduced HRV is associated with the development of numerous conditions for example, diabetes, cardiovascular disease, inflammation, obesity and psychiatric disorders...
April 2018: Behavioural Pharmacology
https://www.readbyqxmd.com/read/29492309/low-maternal-adherence-to-a-mediterranean-diet-is-associated-with-increase-in-methylation-at-the-meg3-ig-differentially-methylated-region-in-female-infants
#9
Sarah Gonzalez-Nahm, Michelle Mendez, Whitney Robinson, Susan K Murphy, Cathrine Hoyo, Vijaya Hogan, Diane Rowley
Diet is dictated by the surrounding environment, as food access and availability may change depending on where one lives. Maternal diet during pregnancy is an important part of the in utero environment, and may affect the epigenome. Studies looking at overall diet pattern in relation to DNA methylation have been lacking. The Mediterranean diet is known for its health benefits, including decreased inflammation, weight loss, and management of chronic diseases. This study assesses the association between maternal adherence to a Mediterranean diet pattern during pregnancy and infant DNA methylation at birth...
May 2017: Environmental Epigenetics
https://www.readbyqxmd.com/read/29483087/dietary-patterns-to-reduce-weight-and-optimize-cardiovascular-health-persuasive-evidence-for-promoting-multiple-healthful-approaches
#10
EDITORIAL
Cheryl A M Anderson
No abstract text is available yet for this article.
March 13, 2018: Circulation
https://www.readbyqxmd.com/read/29438460/practical-dietary-recommendations-for-the-prevention-and-management-of-nonalcoholic-fatty-liver-disease-in-adults
#11
Elena S George, Adrienne Forsyth, Catherine Itsiopoulos, Amanda J Nicoll, Marno Ryan, Siddharth Sood, Stuart K Roberts, Audrey C Tierney
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. In the absence of effective pharmacotherapies, clinical guidelines focus primarily on weight loss to treat this condition. Established consensus, evidence-based, and clinical dietary recommendations for NAFLD are currently lacking. The aim of this paper is to provide evidence-based practical dietary recommendations for the prevention and management of NAFLD in adults. A literature review focusing on established principles for the development of clinical practice recommendations was employed using the following criteria: based on substantial evidence, ensures risk minimization, is flexible for an individual patient approach, and is open to further modification as evidence emerges...
January 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29373032/tissue-level-diet-and-sex-by-diet-interactions-reveal-unique-metabolite-and-clustering-profiles-using-untargeted-liquid-chromatography-mass-spectrometry-on-adipose-skeletal-muscle-and-liver-tissue-in-c57bl6-j-mice
#12
Ann Wells, William T Barrington, Stephen Dearth, Amanda May, David W Threadgill, Shawn R Campagna, Brynn H Voy
Dietary intervention is commonly used for weight loss or to improve health, as diet-induced obesity increases the risk of developing type 2 diabetes, hypertension, cardiovascular disease, stroke, osteoarthritis, and certain cancers. Various dietary patterns are associated with effects on health, yet little is known about the effects of diet at the tissue level. Using untargeted metabolomics, this study aimed to identify changes in water-soluble metabolites in C57BL/6J males and females fed one of five diets (Japanese, ketogenic, Mediterranean, American, and standard mouse chow) for 7 months...
March 2, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29218417/intensive-dietary-intervention-promoting-the-mediterranean-diet-in-people-with-high-cardiometabolic-risk-a-non-randomized-study
#13
M Grimaldi, O Ciano, M Manzo, M Rispoli, M Guglielmi, A Limardi, P Calatola, M Lucibello, S Pardo, B Capaldo, G Riccardi
AIMS: Mediterranean diet (MD) is acknowledged to exert a number of beneficial health effects. We assessed the efficacy and the durability of a 3-month intensive dietary intervention aimed at implementing the MD on body weight and cardiometabolic risk factors in subjects at high risk. METHODS: One hundred and sixteen subjects participated in the study (71 assigned to the intensive intervention and 45 to the conventional intervention). The intensive intervention consisted of 12 weekly group educational meetings and a free-of-charge supply of meals prepared according to the MD model...
March 2018: Acta Diabetologica
https://www.readbyqxmd.com/read/29198435/modifications-of-serum-levels-of-omentin-1-and-other-cardiovascular-risk-factors-following-weight-loss-secondary-to-a-mediterranean-hypocaloric-diet
#14
Daniel Antonio de Luis, Olatz Izaola, David Primo, R Aller
BACKGROUND & AIMS: Omentin-1 might play a role on insulin resistance, dyslipidemia and obesity. The aim of this investigation was to evaluate the influence of weight loss on omentin-1 concentrations after a hypocaloric diet with Mediterranean pattern. METHODS: A Caucasian sample of 67 obese patients was analyzed before and after 3 months on a hypocaloric diet. Anthropometric parameters, blood pressure, fasting blood glucose, C-reactive protein (CRP), fasting insulin, insulin resistance (HOMA-IR), lipid concentrations and omentin-1 were measured...
November 21, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29190720/intramyocellular-triacylglycerol-accumulation-across-weight-loss-strategies-sub-study-of-the-central-trial
#15
RANDOMIZED CONTROLLED TRIAL
Yftach Gepner, Ilan Shelef, Dan Schwarzfuchs, Noa Cohen, Nitzan Bril, Michal Rein, Gal Tsaban, Hila Zelicha, Anat Yaskolka Meir, Lilac Tene, Benjamin Sarusy, Philip Rosen, Jay R Hoffman, Jeffrey R Stout, Joachim Thiery, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Meir J Stampfer, Iris Shai
BACKGROUND: Intramyocellular triacylglycerol (IMTG) is utilized as metabolic fuel during exercise and is linked to insulin resistance, but the long-term effect of weight loss strategies on IMTG among participants with abdominal fat, remain unclear. METHODS: In an 18-month trial, sedentary participants with abdominal fat/dyslipidemia were randomized to either a low-fat (LF) or Mediterranean/low-carbohydrate (MED/LC) diet (including 28g·day-1 of walnuts). After 6-months, the participants were re-randomized to moderate intense physical activity (PA+) or non-physical activity (PA-)...
2017: PloS One
https://www.readbyqxmd.com/read/29154912/role-of-rs1501299-variant-in-the-adiponectin-gene-on-total-adiponectin-levels-insulin-resistance-and-weight-loss-after-a-mediterranean-hypocaloric-diet
#16
Daniel Antonio de Luis, Olatz Izaola, David Primo, Rocio Aller
BACKGROUND/AIM: Several adiponectin gene (ADIPOQ) single nucleotide polymorphisms (SNPS) have been related with adiponectin levels and risk for obesity. Our aim was to analyze the effects of rs1501299 ADIPOQ gene polymorphism on total adiponectin levels, insulin resistance and weight loss after a Mediterranean hypocaloric diet in obese subjects. METHODS: A Caucasian population of 82 obese patients was analyzed, before and after 3 months on a Mediterranean hypocaloric diet...
November 14, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29142011/effect-of-distinct-lifestyle-interventions-on-mobilization-of-fat-storage-pools-central-magnetic-resonance-imaging-randomized-controlled-trial
#17
Yftach Gepner, Ilan Shelef, Dan Schwarzfuchs, Hila Zelicha, Lilac Tene, Anat Yaskolka Meir, Gal Tsaban, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Oded Komy, Arik Wolak, Yoash Chassidim, Rachel Golan, Hila Avni-Hassid, Avital Bilitzky, Benjamin Sarusi, Eyal Goshen, Elad Shemesh, Yaakov Henkin, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Uta Ceglarek, Assaf Rudich, Meir J Stampfer, Iris Shai
BACKGROUND: We aimed to assess whether distinct lifestyle strategies can differentially affect specific body adipose depots. METHODS: We performed an 18-month randomized controlled trial among 278 sedentary adults with abdominal obesity (75%) or dyslipidemia in an isolated workplace with a monitored provided lunch. Participants were randomized to isocaloric low-fat or Mediterranean/low-carbohydrate (MED/LC) diet+28 g walnuts/day with/without added moderate physical activity (PA; 80% aerobic; supervised/free gym membership)...
March 13, 2018: Circulation
https://www.readbyqxmd.com/read/29136612/biochemical-anthropometric-and-lifestyle-factors-related-with-weight-maintenance-after-weight-loss-secondary-to-a-hypocaloric-mediterranean-diet
#18
Daniel Antonio de Luis, Olatz Izaola, David Primo, Hilda F Ovalle, Juan Jose Lopez, Emilia Gomez, Ana Ortola, Rocio Aller
BACKGROUND/AIMS: The aim of our study was to evaluate the influence of lifestyle factors and molecular biomarkers on the maintenance of the weight lost after a hypocaloric Mediterranean diet. DESIGN: After 3 months on a diet, patients (n = 335) remained with no controlled diet during 3 years and they were revaluated. RESULTS: Using linear regression, in the group of responders, we detected that a positive weight loss at 3 months, serum levels of leptin at 3 months, and each 30 min per week of physical activity were associated with weight loss maintenance...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28937599/mediterranean-diet-and-multi-ingredient-based-interventions-for-the-management-of-non-alcoholic-fatty-liver-disease
#19
REVIEW
Manuel Suárez, Noemí Boqué, Josep M Del Bas, Jordi Mayneris-Perxachs, Lluís Arola, Antoni Caimari
Non-alcoholic fatty liver disease (NAFLD) comprises a wide spectrum of hepatic disorders, from simple steatosis to hepatic necro-inflammation leading to non-alcoholic steatohepatitis (NASH). Although the prevalence of these multifactorial pathologies is continuously increasing in the population, there is still not an established methodology for their treatment other than weight loss and a change in lifestyle habits, such as a hypocaloric diet and physical exercise. In this framework, there is increasing evidence that several food bioactives and dietary patterns are effective for reversing and preventing the onset of these pathologies...
September 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28933748/dietary-composition-independent-of-weight-loss-in-the-management-of-non-alcoholic-fatty-liver-disease
#20
REVIEW
Tannaz Eslamparast, Puneeta Tandon, Maitreyi Raman
Poor dietary composition is an important factor in the progression of non-alcoholic fatty liver disease (NAFLD). The majority of NAFLD patients follow diets with overconsumption of simple carbohydrates, total and saturated fat, with reduced intake of dietary fiber and omega-3 rich foods. Although lifestyle modifications including weight loss and exercise remain the keystone of NAFLD management, modifying dietary composition with or without a calorie-restricted diet may also be a feasible and sustainable strategy for NAFLD treatment...
July 26, 2017: Nutrients
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