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https://www.readbyqxmd.com/read/29727647/valorisation-of-blueberry-waste-and-use-of-compression-to-manufacture-sustainable-starch-films-with-enhanced-properties
#1
Cláudia Leites Luchese, Jone Uranga, Jordana Corralo Spada, Isabel Cristina Tessaro, Koro de la Caba
Blueberry waste from juice processing was valorised to develop starch films by compression moulding. The compression process resulted in hydrophobic films with water contact angles even higher than 100° for the films prepared with the highest blueberry waste content. Additionally, the film solubility was reduced by the incorporation of blueberry waste, regardless of the solution pH. These films also exhibited good barrier properties against UV light due to the aromatic compounds present in the blueberry waste...
May 1, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29722492/-koro-syndrome-when-culture-interacts-with-psychopathology
#2
F Elghazouani, M Barrimi
Koro syndrome is a psychiatric disorder specific to certain Asian cultures. It is characterized by acute and intense anxiety with fear of a retraction of the penis into the body and resultant death. We report the case of a 43-year-old Moroccan male presenting with persistent anxiety associated with avoidance behaviors and a chronic belief that his genitalia may shrink or disappear and lead to his death. This impacted his professional and family functioning. The diagnosis of culture-bound syndrome was considered although the presenting syndrome was chronic and sporadic...
2018: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/29668700/chronological-reassessment-of-the-middle-to-upper-paleolithic-transition-and-early-upper-paleolithic-cultures-in-cantabrian-spain
#3
Ana B Marín-Arroyo, Joseba Rios-Garaizar, Lawrence G Straus, Jennifer R Jones, Marco de la Rasilla, Manuel R González Morales, Michael Richards, Jesús Altuna, Koro Mariezkurrena, David Ocio
Methodological advances in dating the Middle to Upper Paleolithic transition provide a better understanding of the replacement of local Neanderthal populations by Anatomically Modern Humans. Today we know that this replacement was not a single, pan-European event, but rather it took place at different times in different regions. Thus, local conditions could have played a role. Iberia represents a significant macro-region to study this process. Northern Atlantic Spain contains evidence of both Mousterian and Early Upper Paleolithic occupations, although most of them are not properly dated, thus hindering the chances of an adequate interpretation...
2018: PloS One
https://www.readbyqxmd.com/read/29617212/physical-education-preservice-teachers-perceptions-about-preparation-for-comprehensive-school-physical-activity-programs
#4
Ja Youn Kwon, Pamela Hodges Kulinna, Hans van der Mars, Mirka Koro-Ljungberg, Audrey Amrein-Beardsley, Jason Norris
PURPOSE: Physical educators may be the responsible people for implementing comprehensive school physical activity programs (CSPAPs) in schools. However, it is unclear whether physical education teacher education (PETE) programs provide the relevant learning opportunities to preservice teachers for CSPAP implementation. The purpose of this study was to understand preservice teachers' perspectives and experiences of CSPAP preparation in their PETE programs. METHOD: Fourteen PETE students from 6 different universities participated and shared their experiences in PETE programs...
April 4, 2018: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29605688/hla-inferred-extended-haplotype-disparity-level-is-more-relevant-then-the-level-of-hla-mismatch-alone-for-the-patients-survival-and-gvhd-in-t-cell-replate-hematopoietic-stem-cell-transplantation-from-unrelated-donor
#5
Jacek Nowak, Klaudia Nestorowicz, Elżbieta Graczyk-Pol, Renata Mika-Witkowska, Marta Rogatko-Koros, Emilia Jaskula, Katarzyna Koscinska, Sylwia Madej, Agnieszka Tomaszewska, Barbara Nasilowska-Adamska, Andrzej Szczepinski, Kazimierz Halaburda, Jaroslaw Dybko, Kazimierz Kuliczkowski, Tomasz Czerw, Sebastian Giebel, Jerzy Holowiecki, Malgorzata Baranska, Anna Pieczonka, Jacek Wachowiak, Anna Czyz, Lidia Gil, Anna Lojko-Dankowska, Mieczyslaw Komarnicki, Maria Bieniaszewska, Agnieszka Kucharska, Andrzej Hellmann, Anna Gronkowska, Wieslaw W Jedrzejczak, Miroslaw Markiewicz, Anna Koclega, Slawomira Kyrcz-Krzemien, Monika Mielcarek, Krzysztof Kalwak, Jan Styczynski, Mariusz Wysocki, Katarzyna Drabko, Beata Wójcik, Jerzy Kowalczyk, Jolanta Gozdzik, Daria Pawliczak, Sławomir Gwozdowicz, Joanna Dziopa, Urszula Szlendak, Agnieszka Witkowska, Marta Zubala, Agnieszka Gawron, Krzysztof Warzocha, Andrzej Lange
Serious risks in unrelated hematopoietic stem cell transplantation (HSCT) including graft versus host disease (GvHD) and mortality are associated with HLA disparity between donor and recipient. The increased risks might be dependent on disparity in not-routinely-tested multiple polymorphisms in genetically dense MHC region, being organized in combinations of two extended MHC haplotypes (Ehp). We assessed the clinical role of donor-recipient Ehp disparity levels in N=889 patients by the population-based detection of HLA allele phase mismatch...
March 29, 2018: Human Immunology
https://www.readbyqxmd.com/read/29480223/phenotypic-characteristics-in-gba-associated-parkinson-s-disease-a-study-in-a-greek-population
#6
Athina Simitsi, Christos Koros, Marina Moraitou, Nikos Papagiannakis, Roubina Antonellou, Maria Bozi, Efthalia Angelopoulou, Maria Stamelou, Helen Michelakakis, Leonidas Stefanis
We compared phenotypic characteristics in 35 Greek patients with Parkinson's disease (PD), carriers of GBA1 mutations (GBA-PD), with 35 Genetically Unidentified PD patients (GU-PD). We found a previously reported higher prevalence of cognitive impairment and a little appreciated more frequent bilateral onset of the disease in GBA-PD vs GU-PD. As far as the exposure to environmental factors, linked to PD, is concerned, our study hints to the possibility that pesticide exposure may be more common in GBA-PD patients, and possibly act synergistically with the mutation carrier status to trigger the disease...
2018: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/29438043/selective-cognitive-impairment-and-hyposmia-in-p-a53t-snca-pd-vs-typical-pd
#7
Christos Koros, Maria Stamelou, Athina Simitsi, Ion Beratis, Dimitra Papadimitriou, Nikolaos Papagiannakis, Stella Fragkiadaki, Dionysia Kontaxopoulou, Sokratis G Papageorgiou, Leonidas Stefanis
OBJECTIVE: To evaluate nonmotor symptoms in early SNCA /p.A53T Parkinson disease (PD) (A53T PD) compared to typical PD (tPD). METHODS: The presence of hyposmia, neuropsychiatric, dysautonomic, and sleep disturbances was assessed by standardized questionnaires and validated scales in 18 patients with A53T PD and 18 patients with tPD, matched for age, sex, and disease duration. All patients were enrolled into the Parkinson's Progression Markers Initiative study. RESULTS: The levodopa equivalent daily dose was higher in the A53T PD ( p = 0...
March 6, 2018: Neurology
https://www.readbyqxmd.com/read/29434309/mixed-matrix-formulations-with-mof-molecular-sieving-for-key-energy-intensive-separations
#8
Gongping Liu, Valeriya Chernikova, Yang Liu, Kuang Zhang, Youssef Belmabkhout, Osama Shekhah, Chen Zhang, Shouliang Yi, Mohamed Eddaoudi, William J Koros
Membrane-based separations can improve energy efficiency and reduce the environmental impacts associated with traditional approaches. Nevertheless, many challenges must be overcome to design membranes that can replace conventional gas separation processes. Here, we report on the incorporation of engineered submicrometre-sized metal-organic framework (MOF) crystals into polymers to form hybrid materials that successfully translate the excellent molecular sieving properties of face-centred cubic (fcu)-MOFs into the resultant membranes...
March 2018: Nature Materials
https://www.readbyqxmd.com/read/29281793/aspects-of-the-belousov-zhabotinsky-reaction-inside-a-self-oscillating-polymer-brush
#9
Tsukuru Masuda, Aya Mizutani Akimoto, Mami Furusawa, Ryota Tamate, Kenichi Nagase, Teruo Okano, Ryo Yoshida
We have developed a novel polymer brush surface exhibiting autonomous swelling-deswelling changes driven by the Belousov-Zhabotinsky (BZ) reaction, that is, the self-oscillating polymer brush. In this system, the ruthenium tris(2,2'-bipyridine) [Ru(bpy)3 ] catalyst-conjugated polymer chains are densely packed on the solid substrate. It is expected that the BZ reaction in the polymer brush would be influenced by the immobilization effect of the catalyst. To clarify the effect of the immobilization of the catalyst on the self-oscillating polymer brush, the self-oscillating behavior of the polymer brush was investigated by comparing it with that of other self-oscillating polymer materials, the free polymer, and the gel particle under various initial substrate concentrations...
January 30, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29218595/quantitative-testing-of-prescriber-knowledge-regarding-the-risks-and-safe-use-of-albiglutide
#10
Carol Koro, Janet Pientka, Veronica Bainbridge, Natalie O'Donnell, Monika Stender, Annette Stemhagen
BACKGROUND: The risk of pancreatitis and potential risk of medullary thyroid carcinoma associated with glucagon-like peptide-1 receptor agonists prompted the US Food and Drug Administration to require a Risk Evaluation and Mitigation Strategy for albiglutide, including education for prescribers and subsequent assessment of their knowledge of the risks and safe use of albiglutide via a quantitative survey. OBJECTIVE: The objective of this study was to assess prescribers' knowledge of the risks related to medullary thyroid carcinoma, pancreatitis, and the appropriate patient population for albiglutide...
March 2018: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/29137437/dna-hypermethyation-and-silencing-of-pitx1-correlated-with-advanced-stage-and-poor-postoperative-prognosis-of-esophageal-squamous-cell-carcinoma
#11
Takeshi Otsubo, Kazuhiko Yamada, Teruki Hagiwara, Kenshiro Oshima, Kei Iida, Koro Nishikata, Tetsuro Toyoda, Toru Igari, Kyoko Nohara, Satoshi Yamashita, Masahira Hattori, Taeko Dohi, Yuki I Kawamura
Esophageal squamous cell carcinoma (ESCC) is associated with the accumulation of genetic and epigenetic changes in the background mucosa. Dysregulated DNA methylation is known to lead to the inactivation of tumor suppressor genes and the activation of oncogenes. To identify the genes whose expression is perturbed by abnormal DNA methylation in ESCC, integrative transcriptomics by serial analysis of gene expression (SAGE) and methylome sequencing by methyl-DNA immunoprecipitation (MeDIP) analysis were performed...
October 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/29129675/alpha-synuclein-dimerization-in-erythrocytes-of-patients-with-genetic-and-non-genetic-forms-of-parkinson-s-disease
#12
Nikolaos Papagiannakis, Christos Koros, Maria Stamelou, Athina-Maria Simitsi, Matina Maniati, Roubina Antonelou, Dimitra Papadimitriou, Georgia Dermentzaki, Marina Moraitou, Helen Michelakakis, Leonidas Stefanis
BACKGROUND: Variations of α-synuclein levels or species have been reported in Parkinson's Disease (PD). There has been little systematic examination of erythrocytes, a rich source of α-synuclein. METHODS: Erythrocyte membranes were obtained from PD patients (mutation carriers in the α-synuclein gene (A53T-PD) and glucocerebrosidase gene (GBA-PD) (n=18 each), and patients without known mutations (GU-PD, n=56)), and age-/sex-matched controls (n=56). Levels of monomeric and dimeric α-synuclein were assessed using Western immunoblotting...
November 9, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29073506/the-oughtness-of-care-fear-stress-and-caregiving-during-the-2000-2001-ebola-outbreak-in-gulu-uganda
#13
Sung-Joon Park, Grace Akello
In this article we introduce the term oughtness of care to show how caring for sick relatives was experienced in the context of the Ebola outbreak in Gulu, Uganda, in 2000-2001. We conducted fieldwork over a nine month period from July 2016 to March 2017 in the suburbs of Lacor, Bardege, Pece Lukung, Kasubi, Limu, and Kanyagoga Koro Layibi, Rwot Obilo, all of which were epicenters for Ebola. In addition, we conducted interviews in the districts of Amuru, Kitgum, and Lamwo, where some interlocutors had resettled following the end of the war that was affecting Gulu at the time of the Ebola outbreak...
October 23, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28867936/cultural-aspects-of-anxiety-disorders-in-india
#14
REVIEW
Maherra Khambaty, Rajesh M Parikh
Cultural factors have influenced the presentation, diagnoses, and treatment of anxiety disorders in India for several centuries. This review covers the antecedents, prevalence, phenomenology, and treatment modalities of anxiety disorders in the Indian cultural context. It covers the history of the depiction of anxiety in India and the concept of culture in the classification of anxiety disorders, and examines the cultural factors influencing anxiety disorders in India. We review the prevalence and phenomenology of various disorders, such as generalized anxiety disorder, panic disorder, social anxiety, and phobic disorder, as well as culture-specific syndromes such as dhat and koro in India...
June 2017: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/28809962/nonlinear-behavior-and-fluctuation-induced-dynamics-in-the-photosensitive-belousov-zhabotinsky-reaction
#15
Valérie Voorsluijs, Ioannis G Kevrekidis, Yannick De Decker
The photosensitive Belousov-Zhabotinsky (pBZ) reaction has been used extensively to study the properties of chemical oscillators. In particular, recent experiments revealed the existence of complex spatiotemporal dynamics for systems consisting of coupled micelles (V < 10-21 L) or droplets (V ≈ [10-8 -10-11 ] L) in which the pBZ reaction takes place. These results have been mostly understood in terms of reaction-diffusion models. However, in view of the small size of the droplets and micelles, large fluctuations of concentrations are to be expected...
August 23, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28801097/chicken-feathers-as-a-natural-source-of-sulphur-to-develop-sustainable-protein-films-with-enhanced-properties
#16
Tania Garrido, Itsaso Leceta, Koro de la Caba, Pedro Guerrero
In this work, the effect of hydrolyzed keratin on the properties of soy protein-based films was analyzed when different manufacture processes were employed. It is widely known that the processing method selected can affect the film properties as a function of the structure obtained during the film formation. Therefore, the assessment of hydrolyzed keratin/soy protein films processed by casting and compression moulding was carried out by means of the analysis of physicochemical, thermal, mechanical, optical and surface properties...
January 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28789885/ultra-thin-hydro-films-based-on-lactose-crosslinked-fish-gelatin-for-wound-healing-applications
#17
Alaitz Etxabide, Claudia Vairo, Edorta Santos-Vizcaino, Pedro Guerrero, Jose Luis Pedraz, Manoli Igartua, Koro de la Caba, Rosa Maria Hernandez
This study focuses on the development and characterization of an ultra thin hydro-film based on lactose-mediated crosslinking of fish gelatin by Maillard reaction. Lactose results in the only efficient crosslinker able to produce resistant to handling hydro-films when compared to conventional crosslinkers such as glutaraldehyde or genipin (tested at 25 and 37°C in phosphate buffer saline solution (PBS)).The disappearance of the peak related to the N-containing groups (XPS) and the images obtained by SEM and AFM demonstrate the highly ordered nano-scaled structure of lactose-crosslinked gelatin, confirming the crosslinking efficiency...
September 15, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28717164/glucagon-like-peptide-1-reduces-pancreatic-%C3%AE-cell-mass-through-hypothalamic-neural-pathways-in-high-fat-diet-induced-obese-rats
#18
Hisae Ando, Koro Gotoh, Kansuke Fujiwara, Manabu Anai, Seiichi Chiba, Takayuki Masaki, Tetsuya Kakuma, Hirotaka Shibata
We examined whether glucagon-like peptide-1 (GLP-1) affects β-cell mass and proliferation through neural pathways, from hepatic afferent nerves to pancreatic efferent nerves via the central nervous system, in high-fat diet (HFD)-induced obese rats. The effects of chronic administration of GLP-1 (7-36) and liraglutide, a GLP-1 receptor agonist, on pancreatic morphological alterations, c-fos expression and brain-derived neurotrophic factor (BDNF) content in the hypothalamus, and glucose metabolism were investigated in HFD-induced obese rats that underwent hepatic afferent vagotomy (VgX) and/or pancreatic efferent sympathectomy (SpX)...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28671716/ultraselective-carbon-molecular-sieve-membranes-with-tailored-synergistic-sorption-selective-properties
#19
Chen Zhang, William J Koros
Membrane-based separations can reduce the energy consumption and the CO2 footprint of large-scale fluid separations, which are traditionally practiced by energy-intensive thermally driven processes. Here, a new type of membrane structure based on nanoporous carbon is reported, which, according to this study, is best referred to as carbon/carbon mixed-matrix (CCMM) membranes. The CCMM membranes are formed by high-temperature (up to 900 °C) pyrolysis of polyimide precursor hollow-fiber membranes. Unprecedentedly high permselectivities are seen in CCMM membranes for CO2 /CH4 , N2 /CH4 , He/CH4 , and H2 /CH4 separations...
September 2017: Advanced Materials
https://www.readbyqxmd.com/read/28554408/genetics-of-parkinson-s-disease-genotype-phenotype-correlations
#20
Christos Koros, Athina Simitsi, Leonidas Stefanis
Since the first discovery of a specific genetic defect in the SNCA gene, encoding for α-synuclein, as a causative factor for Parkinson's disease 20 years ago, a multitude of other genes have been linked to this disease in rare cases with Mendelian inheritance. Furthermore, the genetic contribution to the much more common sporadic disease has been demonstrated through case control association studies and, more recently, genome-wide association studies. Interestingly, some of the genes with Mendelian inheritance, such as SNCA, are also relevant to the sporadic disease, suggesting common pathogenetic mechanisms...
2017: International Review of Neurobiology
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