Read by QxMD icon Read


Kanami Saito, Hisae Ando, Koro Goto, Tetsuya Kakuma, Yasushi Kawano, Hisashi Narahara, Yutaka Hatano, Sakuhei Fujiwara
No abstract text is available yet for this article.
October 2016: Annals of Dermatology
Gongping Liu, Nanwen Li, Stephen J Miller, Danny Kim, Shouliang Yi, Ying Labreche, William J Koros
New rigid polyimides with bulky CF3 groups were synthesized and engineered into high-performance hollow fiber membranes. The enhanced rotational barrier provided by properly positioned CF3 side groups prohibited fiber transition layer collapse during cross-linking, thereby greatly improving CO2 /CH4 separation performance compared to conventional materials for aggressive natural gas feeds.
October 24, 2016: Angewandte Chemie
Masahide Okamoto, Mitsuhiro Okamoto, Koro Gotoh, Takayuki Masaki, Yoshinori Ozeki, Hisae Ando, Manabu Anai, Asami Sato, Yuichi Yoshida, So Ueda, Tetsuya Kakuma, Hirotaka Shibata
Anti-programmed cell death-1 (PD-1) antibodies are regarded as a risk factor for insulin-dependent diabetes mellitus as a side effect. While a small number of cases have been reported, evidence remains limited. This is the first report of an Asian patient developing insulin-dependent diabetes during anti-PD-1 therapy. A 55-year-old euglycemic woman receiving nivolumab for malignant melanoma showed abrupt onset of ketonuria and elevated levels of plasma glucose (580 mg/dl) and hemoglobin (Hb)A1c (7.0%). Over the next 2 weeks, serum C-peptide levels fell below the limit of detection...
April 18, 2016: Journal of Diabetes Investigation
Ali A Rownaghi, Amit Kant, Xin Li, Harshul Thakkar, Amit Hajari, Yingxin He, Patrick J Brennan, Hooman Hosseini, William J Koros, Fateme Rezaei
In this work, the development of novel binary and ternary oxide/Torlon hollow fiber composites comprising zirconia, titania, and silica as amine supports was demonstrated. The resulting binary (Zr-Si/PAI-HF, Ti-Si/PAI-HF) and ternary (Zr-Ti-Si/PAI-HF) composites were then functionalized with monoamine-, diamine-, and triamine-substituted trialkoxysilanes and were evaluated in CO2 capture. Although the introduction of both Zr and Ti improved the CO2 adsorption capacity relative to that with Si/PAI-HF sorbents, zirconia was found to have a more favorable effect on the CO2 adsorption performance than titania, as previously demonstrated for amine sorbents in the powder form...
May 23, 2016: ChemSusChem
F Koro Koro, A F Ngatchou, J L Portal, C Gutierrez, F X Etoa, S I Eyangoh
Bovine tuberculosis is still prevalent and under-evaluated in cattle destined for human consumption in Cameroon. Potential reservoirs of the disease include livestock imported from countries endemic for bovine tuberculosis, such as Nigeria and Chad, and potential residual reservoirs in local livestock and wildlife. Few studies have been done in Cameroon to genotype the Mycobacterium tuberculosis complex (MTC) strains responsible for bovine tuberculosis. The aim of this work is to describe the population structure of MTC strains isolated from cattle, using spoligotyping as the genotyping method...
December 2015: Revue Scientifique et Technique
Dimitra Papadimitriou, Roubina Antonelou, Michael Miligkos, Matina Maniati, Nikolaos Papagiannakis, Sevasti Bostantjopoulou, Athannassios Leonardos, Christos Koros, Athina Simitsi, Sokratis G Papageorgiou, Elisabeth Kapaki, Roy N Alcalay, Alexandros Papadimitriou, Aglaia Athanassiadou, Maria Stamelou, Leonidas Stefanis
BACKGROUND: G209A SNCA mutation carriers represent an important group of genetic PD. We describe motor and nonmotor features of G209A SNCA mutation carriers. METHODS: Longitudinal clinical assessments over 2 years were collected in 22 symptomatic and 8 asymptomatic G209A SNCA mutation carriers. Motor and nonmotor rating scales were administered. Correlations were performed between clinical variables and disease duration or age. Penetrance was calculated using Kaplan-Meier survival curves...
August 2016: Movement Disorders: Official Journal of the Movement Disorder Society
Grace Chen, William J Koros, Christopher W Jones
Zeolite NaY and metal organic frameworks MIL-53(Al) and UiO-66(Zr) are spun with cellulose acetate (CA) polymer to create hybrid porous composite fibers for the selective adsorption of sulfur odorant compounds from pipeline natural gas. Odorant removal is desirable to limit corrosion associated with sulfur oxide production, thereby increasing lifetime in gas turbines used for electricity generation. In line with these goals, the performance of the hybrid fibers is evaluated on the basis of sulfur sorption capacity and selectivity, as well as fiber stability and regenerability, compared to their polymer-free sorbent counterparts...
April 20, 2016: ACS Applied Materials & Interfaces
Anna Kats, Maria Norgård, Zenebech Wondimu, Catalin Koro, Hernán Concha Quezada, Göran Andersson, Tülay Yucel-Lindberg
Periodontitis is characterized by chronic inflammation and osteoclast-mediated bone loss regulated by the receptor activator of nuclear factor-κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG). The aim of this study was to investigate the effect of aminothiazoles targeting prostaglandin E synthase-1 (mPGES-1) on RANKL- and lipopolysaccharide (LPS)-mediated osteoclastogenesis and prostaglandin E2 (PGE2 ) production in vitro using the osteoclast precursor RAW 264.7 cells. RAW 264.7 cells were treated with RANKL or LPS alone or in combination with the aminothiazoles 4-([4-(2-naphthyl)-1,3-thiazol-2-yl]amino)phenol (TH-848) or 4-(3-fluoro-4-methoxyphenyl)-N-(4-phenoxyphenyl)-1,3-thiazol-2-amine (TH-644)...
June 2016: Journal of Cellular and Molecular Medicine
Andrea A Kim, Irene Mukui, Lucy N'gan'ga, Abraham Katana, Dan Koros, Joyce Wamicwe, Kevin M De Cock
BACKGROUND: In 2014, the Joint United Nations Programme on HIV/AIDS (UNAIDS) called for 90% of persons living with HIV (PLHIV) to know their status, 90% of these to be on antiretroviral therapy (ART), and 90% of these to be virally suppressed by 2020 (90-90-90). It is not clear whether planned ART scale-up in countries whose eligibility criteria for ART initiation are based on recommendations from the 2013 World Health Organization treatment guidelines will be sufficient to meet UNAIDS' new global targets...
2016: PloS One
Catalin Koro, Annelie Hellvard, Nicolas Delaleu, Veronika Binder, Carsten Scavenius, Brith Bergum, Izabela Główczyk, Helen M Roberts, Iain L C Chapple, Melissa M Grant, Maria Rapala-Kozik, Kinga Klaga, Jan J Enghild, Jan Potempa, Piotr Mydel
Carbamylation of lysine residues and protein N-termini is an ubiquitous, non-enzymatic post-translational modification. Carbamylation at sites of inflammation is due to cyanate formation during the neutrophil oxidative burst and may target lysine residues within the antimicrobial peptide LL-37. The bactericidal and immunomodulatory properties of LL-37 depend on its secondary structure and cationic nature, which are conferred by arginine and lysine residues. Therefore, carbamylation may affect the biological functions of LL-37...
April 2016: Innate Immunity
Parveen K Garg, Alice M Arnold, Karen D Hinckley Stukovsky, Carol Koro, Nancy S Jenny, Kenneth J Mukamal, Michael H Criqui, Curt D Furberg, Anne B Newman, Mary Cushman
OBJECTIVE: Although prior studies report a relationship between elevated lipoprotein-associated phospholipase A2 (Lp-PLA2) and incident cardiovascular disease, the prospective association of Lp-PLA2 with incident peripheral arterial disease (PAD) has not been studied. We investigated the association between Lp-PLA2 mass and activity and the risk of developing clinical PAD and low ankle-brachial index (ABI). APPROACH AND RESULTS: Among Cardiovascular Health Study participants, a population-based cohort of 5888 adults aged ≥65 years enrolled in 1989 to 1990, Lp-PLA2 mass and activity were measured in 4537 individuals without baseline PAD...
April 2016: Arteriosclerosis, Thrombosis, and Vascular Biology
Regina Bussing, Dana Mason, Cynthia Wilson Garvan, Tina Gurnani, Mirka Koro-Ljungberg, Kenji Noguchi, Dolores Albarracin
Little is known about perceptions surrounding self-management for attention deficit hyperactivity disorder (ADHD), although such interventions appear commonly used and are considered essential components of the chronic care model. Our research is part of a mixed methods study that followed students at high and low risk for ADHD over 11 years. During the final study years, area-representative samples of 148 adolescents (54.8% participation; 97 ADHD high-risk group; 51 low-risk peers) and 161 parents (59.4% participation; 108 parents of high-risk adolescent; 53 parents of low-risk peer) completed a cross-sectional survey on community-identified self-management interventions for ADHD (activity outlets, sleep regulation, dietary restriction, homework help, family rules, and prayer)...
February 1, 2016: Journal of Child and Family Studies
Nikolaos Papagiannakis, Maria Xilouri, Christos Koros, Maria Stamelou, Roubina Antonelou, Matina Maniati, Dimitra Papadimitriou, Marina Moraitou, Helen Michelakakis, Leonidas Stefanis
BACKGROUND: Reduced expression of lysosomal-associated membrane protein 2a and heatshock-cognate 70 proteins, involved in chaperone-mediated autophagy and of glucocerebrosidase, is reported in PD brains. The aim of this study was to identify systemic alterations in lysosomal-associated membrane protein 2a, heatshock cognate-70, and glucocerebrosidase levels/activity in peripheral blood mononuclear cells from PD patients. METHODS: Protein/mRNA levels were assessed in PD patients from genetically undetermined background, alpha-synuclein (G209A/A53T), or glucocerebrosidase mutation carriers and age-/sex-matched controls...
November 2015: Movement Disorders: Official Journal of the Movement Disorder Society
Taishi Aosa, Seiichi Chiba, Hirokazu Kitamura, Keisuke Ina, Shuji Tatsukawa, Chinatsu Moriwaki, Huixing Wei, Koro Gotoh, Takayuki Masaki, Tetsuya Kakuma, Hirotaka Shibata, Yoshihisa Fujikura
Stress-induced inflammatory responses in the portal system are characterized by elevations in serum concentrations of interleukin-6 (IL-6) and endotoxins such as lipopolysaccharides (LPS). LPS translocation from the intestinal to the capillary lumen occurs via LPS endocytosis by the capillary endothelium. Because the capillary endothelium of the small intestinal submucosa is fenestrated, we determined the role of pore modifications within the fenestrated endothelium in relaying inflammatory stress responses in the portal vein...
July 2016: Histology and Histopathology
Chen Zhang, William J Koros
ZIFs are a unique class of porous solids topologically associated with zeolites, but dramatically different in components. Current research on ZIF-enabled membranes is highly imbalanced. Despite a large selection of available ZIF materials, seven out of ten published papers discuss ZIF-8-based membranes. This is partially due to insufficient knowledge on ZIFs' structure-transport property relationships as well as lack of capability to tailor their transport properties for particular separations. This Perspective will provide an account of recent progress in ZIF-enabled membranes and analyze the barriers that must be overcome to advance ZIF-enabled membranes beyond fundamental characterizations...
October 1, 2015: Journal of Physical Chemistry Letters
Anna Lundmark, Haleh Davanian, Tove Båge, Gunnar Johannsen, Catalin Koro, Joakim Lundeberg, Tülay Yucel-Lindberg
The multifactorial chronic inflammatory disease periodontitis, which is characterized by destruction of tooth-supporting tissues, has also been implicated as a risk factor for various systemic diseases. Although periodontitis has been studied extensively, neither disease-specific biomarkers nor therapeutic targets have been identified, nor its link with systemic diseases. Here, we analyzed the global transcriptome of periodontitis and compared its gene expression profile with those of other inflammatory conditions, including cardiovascular disease (CVD), rheumatoid arthritis (RA), and ulcerative colitis (UC)...
December 21, 2015: Scientific Reports
João Gama Marques
No abstract text is available yet for this article.
December 2015: Psychiatria Danubina
Juanjuan Zhuang, Xinsheng Lai
No abstract text is available yet for this article.
August 2015: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Christos Koros, Maria Stamelou
Progressive supranuclear palsy (PSP) an atypical parkinsonian with a common phenotype comprising early falls, the characteristic slowing of vertical saccades and a frontal syndrome with marked apathy (Richardson's syndrome). Currently, no effective symptomatic or neuroprotective treatment is available for PSP. Current medical have a limited role in PSP. Novel experimental treatments include davunetide or tideglusib, both inhibitors of glycogen synthase kinase-3 (GSK-3) that failed to improve the clinical outcome of PSP patients in two recent studies...
January 2016: Parkinsonism & related Disorders
Chen Zhang, William J Koros
Understanding how to control transport properties of zeolitic imidazolate frameworks (ZIFs) is critical to extend ZIF-based membranes and adsorbents to a wide spectrum of gas and vapor separations. In this work, we report a facile post-synthetic thermal modification (PSTM) technique to tailor ZIFs' transport properties by balancing diffusivity and diffusion selectivity. With controllable dissociation of framework methyl groups from a precursor ZIF (ZIF-8), we have prepared thermally modified ZIFs showing substantially increased n-butane diffusivity and attractive n/iso-butane diffusion selectivity...
October 28, 2015: ACS Applied Materials & Interfaces
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"